LOCUS       XM_047417589            5387 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens nephrocystin 4 (NPHP4), transcript variant
            X18, mRNA.
ACCESSION   XM_047417589
VERSION     XM_047417589.1
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000001.11) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5387
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="1"
     gene            1..5387
                     /gene="NPHP4"
                     /gene_synonym="POC10; SLSN4"
                     /note="nephrocystin 4; Derived by automated computational
                     analysis using gene prediction method: Gnomon. Supporting
                     evidence includes similarity to: 3 mRNAs, 42 ESTs, 222
                     long SRA reads, 5 Proteins, and 99% coverage of the
                     annotated genomic feature by RNAseq alignments, including
                     1 sample with support for all annotated introns"
                     /db_xref="GeneID:261734"
                     /db_xref="HGNC:HGNC:19104"
                     /db_xref="MIM:607215"
     CDS             1181..4933
                     /gene="NPHP4"
                     /gene_synonym="POC10; SLSN4"
                     /codon_start=1
                     /product="nephrocystin-4 isoform X10"
                     /protein_id="XP_047273545.1"
                     /db_xref="GeneID:261734"
                     /db_xref="HGNC:HGNC:19104"
                     /db_xref="MIM:607215"
                     /translation="MTLIENCSLQYTLKPHPALEPAFHLLPENLLVSGLQQIPGLLPA
                     HGESGDALRKPRLQKPITGHLDDLFFTLYPSLEKFEEELLELHVQDHFQEGCGPLDGG
                     ALEILERRLRVGVHNGLGFVQRPQVVVLVPEMDVALTRSASFSRKVVSSSKTSSGSQA
                     LVLRSRLRLPEMVGHPAFAVIFQLEYVFSSPAGVDGNAASVTSLSNLACMHMVRWAVW
                     NPLLEADSGRVTLPLQGGIQPNPSHCLVYKVPSASMSSEEVKQVESGTLRFQFSLGSE
                     EHLDAPTEPVSGPKVERRPSRKPPTSPSSPPAPVPRVLAAPQNSPVGPGLSISQLAAS
                     PRSPTQHCLARPTSQLPHGSQASPAQAQEFPLEAGISHLEADLSQTSLVLETSIAEQL
                     QELPFTPLHAPIVVGTQTRSSAGQPSRASMVLLQSSGFPEILDANKQPAEAVSATEPV
                     TFNPQKEESDCLQSNEMVLQFLAFSRVAQDCRGTSWPKTVYFTFQFYRFPPATTPRLQ
                     LVQLDEAGQPSSGALTHILVPVSRDGTFDAGSPGFQLRYMVGPGFLKPGERRCFARYL
                     AVQTLQIDVWDGDSLLLIGSAAVQMKHLLRQGRPAVQASHELEVVATEYEQDNMVVSG
                     DMLGFGRVKPIGVHSVVKGRLHLTLANVGHPCEQKVRGCSTLPPSRSRVISNDGASRF
                     SGGSLLTTGSSRRKHVVQAQKLADVDSELAAMLLTHARQGKGPQDVSRESDATRRRKL
                     ERMRSVRLQEAGGDLGRRGTSVLAQQSVRTQHLRDLQVIAAYRERTKAESIASLLSLA
                     ITTEHTLHATLGVAEFFEFVLKNPHNTQHTVTVEIDNPELSVIVDSQEWRDFKGAAGL
                     HTPVEEDMFHLRGSLAPQLYLRPHETAHVPFKFQSFSAGQLAMVQASPGLSNEKGMDA
                     VSPWKSSAVPTKHAKVLFRASGGKPIAVLCLTVELQPHVVDQVFRFYHPELSFLKKAI
                     RLPPWHTFPGAPVGMLGEDPPVHVRCSDPNVICETQNVGPGEPRDIFLKVASGPSPEI
                     KDFFVIIYSDRWLATPTQTWQVYLHSLQRVDVSCVAGQLTRLSLVLRGTQTVRKVRAF
                     TSHPQELKTDPKGVFVLPPRGVQDLHVGVRPLRAGSRFVHLNLVDVDCHQLVASWLVC
                     LCCRQPLISKAFEIMLAAGEGKGVNKRITYTNPYPSRRTFHLHSDHPELLRFREDSFQ
                     VGGGETYTIGLQFAPSQRVGEEEILIYINDHEDKNEEAFCVKVIYQ"
ORIGIN      
        1 ctggcctctc tgcagcccct cggctgaagg gagcgcggta ccgatgttct gggccttggc
       61 tccccgcgcc ctagtccgcg cgcatccttc ccaggccgga gtccgcggac cccgcctggc
      121 cgcgcccctc cgcccctcct ccccgccccc cggctccagc tccggctccg gctgtcagtt
      181 ccccgcggtg gctctgcggc cttcgggcgt ccctgcgagg ctttgtaccc ggcgccgtcc
      241 cggccttctg cgcccctttc ctgccttgga acctcccggc cgacccggcc cggaaggcgc
      301 cacccgctcc cgcgtgccct tccccacgcg tgcaggctgc tcccgcccgc ccccgggctt
      361 gcaggcacct cgctgcccga gattcctcgt gtctaacttc ttaggagacc gctgctttct
      421 gcctccgtgt gtcgcgatgt gtggctttgg tggacgtctg tgaaggaaat ccagcctctc
      481 gcgtgtgtag ttggcaaaag gaggagtatt tctgttgatg gtgggcagcg cctcccggtc
      541 ctaacccagg gctccgttcg ttgcacctcc tctgtgcagt ttccatgctt gaagacagca
      601 catttgacag ccttcttatg cactggaaca caagtgctcg ggaaatagtt gctgaataga
      661 tcagcagaag cagagatctc aaggagattt cacagctctc attttggaga gagcgcgcca
      721 gccttggaag gaatccacgg cattccagtg tgtcctcaag tggctggacg gaccggtaat
      781 taggcagggc gtgctggagg tactgtcaga ggttgaatgc catctgcgag tgtctttctt
      841 tgatgtcacc taccggcact tctttgggag gacgtggaaa accacagtga agccgacgaa
      901 gagaccgccg tccaggatcg tctttaatga gcccttgtat tttcacacat ccctaaacca
      961 ccctcatatc gtggctgtgg tggaagtggt cgctgagggc aagaaacggg atgggagcct
     1021 ccagacattg tcctgtgggt ttggaattct tcggatcttc agcaaccagc cggactctcc
     1081 tatctctgct tcccaggaca aaaggttgcg gctgtaccat ggcaccccca gagccctcct
     1141 gcacccgctt ctccaggacc ccgcagagca aaacagacac atgaccctca ttgagaactg
     1201 cagcctgcag tacacgctga agccacaccc ggccctggag cctgcgttcc accttcttcc
     1261 tgagaacctt ctggtgtctg gtctgcagca gatacctggc ctgcttccag ctcatggaga
     1321 atccggcgac gctctccgaa agcctcgcct ccagaagccc atcacggggc acttggatga
     1381 cttattcttc accctgtacc cctccctgga gaagtttgag gaagagctgc tggagctcca
     1441 cgtccaggac cacttccagg agggatgtgg cccactggac ggtggtgccc tggagatcct
     1501 ggagcggcgc ctgcgtgtgg gcgtgcacaa tggtctgggc ttcgtgcaga ggccgcaggt
     1561 cgttgtactg gtgcctgaga tggatgtggc cttgacgcgc tcagctagct tcagcaggaa
     1621 agtggtctcc tcttccaaga ccagctccgg gagccaagct ctggttttga gaagccgcct
     1681 ccgcctccca gagatggtcg gccaccctgc atttgcggtc atcttccagc tggagtacgt
     1741 gttcagcagc cctgcaggag tggacggcaa tgcagcttcg gtcacctctc tgtccaacct
     1801 ggcatgcatg cacatggtcc gctgggctgt ttggaacccc ttgctggaag ctgattctgg
     1861 aagggtgacc ctgcctctgc agggtgggat ccagcccaac ccctcgcact gtctggtcta
     1921 caaggtaccc tcagccagca tgagctctga agaggtgaag caggtggagt cgggtacact
     1981 ccggttccag ttctcgctgg gctcagaaga acacctggat gcacccacgg agcctgtcag
     2041 tggccccaaa gtggagcggc ggccttccag gaaaccaccc acgtcccctt cgagcccgcc
     2101 agcgccagta cctcgagttc tcgctgcccc gcagaactca cctgtgggac cagggttgtc
     2161 aatttcccag ctggcggcct ccccgcggtc cccgactcag cactgcttgg ccaggcctac
     2221 ttcacagcta ccccatggct ctcaggcctc cccggcccag gcacaggagt tcccgttgga
     2281 ggccggtatc tcccacctgg aagccgacct gagccagacc tccctggtcc tggaaacatc
     2341 cattgccgaa cagttacagg agctgccgtt cacgcctttg catgccccta ttgttgtggg
     2401 aacccagacc aggagctctg cagggcagcc ctcgagagcc tccatggtgc tcctgcagtc
     2461 ctccggcttt cccgagattc tggatgccaa taaacagcca gccgaggctg tcagcgctac
     2521 agaacctgtg acgtttaacc ctcagaagga agaatcagat tgtctacaaa gcaacgagat
     2581 ggtgctacag tttcttgcct ttagcagagt ggcccaggac tgccgaggaa catcatggcc
     2641 aaagactgtg tatttcacct tccagttcta ccgcttccca cccgcaacga cgccacgact
     2701 gcagctggtc cagctggatg aggccggcca gcccagctct ggcgccctga cccacatcct
     2761 cgtgcctgtg agcagagatg gcacctttga tgctgggtct cctggcttcc agctgaggta
     2821 catggtgggc cctgggttcc tgaagccagg tgagcggcgc tgctttgccc gctacctggc
     2881 cgtgcagacc ctgcagattg acgtctggga cggagactcc ctgctgctca tcggatctgc
     2941 tgccgtccag atgaagcatc tcctccgcca aggccggccg gctgtgcagg cctcccacga
     3001 gcttgaggtc gtggcaactg aatacgagca ggacaacatg gtggtgagtg gagacatgct
     3061 ggggtttggc cgcgtcaagc ccatcggcgt ccactcggtg gtgaagggcc ggctgcacct
     3121 gactttggcc aacgtgggtc acccgtgtga acagaaagtg agaggttgta gcacattgcc
     3181 accgtccaga tctcgggtca tctcaaacga tggagccagc cgcttctctg gaggcagcct
     3241 cctcacgact ggaagctcaa ggcgaaaaca cgtggtgcaa gcacagaagc tggcggacgt
     3301 ggacagtgag ctggctgcca tgctactgac ccatgcccgg cagggcaagg ggccccagga
     3361 cgtcagccgc gagtcggatg ccacccgcag gcgtaagctg gagcggatga ggtctgtgcg
     3421 cctgcaggag gccgggggag acttgggccg gcgcgggacg agcgtgttgg cgcagcagag
     3481 cgtccgcaca cagcacttgc gggacctaca ggtcatcgcc gcctaccggg aacgcacgaa
     3541 ggccgagagc atcgccagcc tgctgagcct ggccatcacc acggagcaca cgctccacgc
     3601 cacgctgggg gtcgccgagt tctttgagtt tgtgcttaag aacccccaca acacacagca
     3661 cacggtgact gtggagatcg acaaccccga gctcagcgtc atcgtggaca gtcaggagtg
     3721 gagggacttc aagggtgctg ctggcctgca cacaccggtg gaggaggaca tgttccacct
     3781 gcgtggcagc ctggcccccc agctctacct gcgcccccac gagaccgccc acgtcccctt
     3841 caagttccag agcttctctg cagggcagct ggccatggtg caggcctctc ctgggttgag
     3901 caacgagaag ggcatggacg ccgtgtcacc ttggaagtcc agcgcagtgc ccactaaaca
     3961 cgccaaggtc ttgttccgag cgagtggtgg caagcccatc gccgtgctct gcctgactgt
     4021 ggagctgcag ccccacgtgg tggaccaggt cttccgcttc tatcacccgg agctctcctt
     4081 cctgaagaag gccatccgcc tgccgccctg gcacacattt ccaggtgctc cggtgggaat
     4141 gcttggtgag gaccccccag tccatgttcg ctgcagcgac ccgaacgtca tctgtgagac
     4201 ccagaatgtg ggccccgggg aaccacggga catatttctg aaggtggcca gtggtccaag
     4261 cccggagatc aaagacttct ttgtcatcat ttactcggat cgctggctgg cgacacccac
     4321 acagacgtgg caggtctacc tccactccct gcagcgcgtg gatgtctcct gcgtcgcagg
     4381 ccagctgacc cgcctgtccc ttgtccttcg ggggacacag acagtgagga aagtgagagc
     4441 tttcacctct catccccagg agctgaagac agaccccaaa ggtgtcttcg tgctgccgcc
     4501 tcgtggggtg caggacctgc atgttggcgt gaggcccctt agggccggca gccgctttgt
     4561 ccatctcaac ctggtggacg tggattgcca ccagctggtg gcctcctggc tcgtgtgcct
     4621 ctgctgccgc cagccgctca tctccaaggc ctttgagatc atgttggctg cgggcgaagg
     4681 gaagggtgtc aacaagagga tcacctacac caacccctac ccctcccgga ggacattcca
     4741 cctgcacagc gaccacccgg agctgctgcg gttcagagag gactccttcc aggtcggggg
     4801 tggagagacc tacaccatcg gcttgcagtt tgcgcctagt cagagagtgg gtgaggagga
     4861 gatcctgatc tacatcaatg accatgagga caaaaacgaa gaggcatttt gcgtgaaggt
     4921 catctaccag tgagggcttg agggtgacgt ccttcctgcg gcacccagct ggggcctgtc
     4981 tgtgcccctc ctgccctgca ggctgtcctc cccgcctctc tgcagccttt cacttcagtg
     5041 cccacctggc tgacctgtgc acttggctga ggaagcagag accgagcgct ggtcattttg
     5101 tagtacctgc atccagctta gctgctgctg acacccagca ggcctgggtt ccgtgagcgc
     5161 gaactccgtg gtggtgggtc tggctctggt gctgccatct acgcatgtgg gaccctcgtt
     5221 atcgctgttg ctcaaaatgt attttatgaa tcatcctaaa tgagaaaatt atgtttttct
     5281 tactggattt tgtacaaaca taatctatta tttgctatgc aatattttat gctggtatta
     5341 tatctgtttt ttaaattgtt gaacaaaata ctaaactttt acacgtc
//
