LOCUS       XM_017027463            4092 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens NLR family pyrin domain containing 12
            (NLRP12), transcript variant X9, mRNA.
ACCESSION   XM_017027463
VERSION     XM_017027463.2
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq; includes ab initio.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000019.10) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Apr 5, 2022 this sequence version replaced XM_017027463.1.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
            
            ##RefSeq-Attributes-START##
            ab initio :: 15% of CDS bases
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..4092
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="19"
     gene            1..4092
                     /gene="NLRP12"
                     /gene_synonym="CLR19.3; FCAS2; NALP12; PAN6; PYPAF7; RNO;
                     RNO2"
                     /note="NLR family pyrin domain containing 12; Derived by
                     automated computational analysis using gene prediction
                     method: Gnomon. Supporting evidence includes similarity
                     to: 3 ESTs, 8 long SRA reads, and 85% coverage of the
                     annotated genomic feature by RNAseq alignments, including
                     1 sample with support for all annotated introns"
                     /db_xref="GeneID:91662"
                     /db_xref="HGNC:HGNC:22938"
                     /db_xref="MIM:609648"
     CDS             856..3627
                     /gene="NLRP12"
                     /gene_synonym="CLR19.3; FCAS2; NALP12; PAN6; PYPAF7; RNO;
                     RNO2"
                     /codon_start=1
                     /product="NACHT, LRR and PYD domains-containing protein 12
                     isoform X9"
                     /protein_id="XP_016882952.1"
                     /db_xref="GeneID:91662"
                     /db_xref="HGNC:HGNC:22938"
                     /db_xref="MIM:609648"
                     /translation="MEDRNARLGECVNLSHRYTRLLLVKEHSNPMQVQQQLLDTGRGH
                     ARTVGHQASPIKIETLFEPDEERPEPPRTVVMQGAAGIGKSMLAHKVMLDWADGKLFQ
                     GRFDYLFYINCREMNQSATECSMQDLIFSCWPEPSAPLQELIRVPERLLFIIDGFDEL
                     KPSFHDPQGPWCLCWEEKRPTELLLNSLIRKKLLPELSLLITTRPTALEKLHRLLEHP
                     RHVEILGFSEAERKEYFYKYFHNAEQAGQVFNYVRDNEPLFTMCFVPLVCWVVCTCLQ
                     QQLEGGGLLRQTSRTTTAVYMLYLLSLMQPKPGAPRLQPPPNQRGLCSLAADGLWNQK
                     ILFEEQDLRKHGLDGEDVSAFLNMNIFQKDINCERYYSFIHLSFQEFFAAMYYILDEG
                     EGGAGPDQDVTRLLTEYAFSERSFLALTSRFLFGLLNEETRSHLEKSLCWKVSPHIKM
                     DLLQWIQSKAQSDGSTLQQGSLEFFSCLYEIQEEEFIQQALSHFQVIVVSNIASKMEH
                     MVSSFCLKRCRSAQVLHLYGATYSADGEDRARCSAGAHTLLVQLRPERTVLLDAYSEH
                     LAAALCTNPNLIELSLYRNALGSRGVKLLCQGLRHPNCKLQNLRLKRCRISSSACEDL
                     SAALIANKNLTRMDLSGNGVGFPGMMLLCEGLRHPQCRLQMIQLRKCQLESGACQEMA
                     SVLGTNPHLVELDLTGNALEDLGLRLLCQGLRHPVCRLRTLWLKICRLTAAACDELAS
                     TLSVNQSLRELDLSLNELGDLGVLLLCEGLRHPTCKLQTLRLGICRLGSAACEGLSVV
                     LQANHNLRELDLSFNDLGDWGLWLLAEGLQHPACRLQKLWLDSCGLTAKACENLYFTL
                     GINQTLTDLYLTNNALGDTGVRLLCKRLSHPGCKLRVLWLFGMDLNKMTHSRLAALRV
                     TKPYLDIGC"
ORIGIN      
        1 agaacagcca ttggtgagtg gggcagggca ggagggaact gaagagtgag aaagcattat
       61 ttcagcaaaa ggtctttcct cccttgctct ctcctccaac cactggctca gcctctccgc
      121 ccgctgcctg tgaatgatgc aatggaaggt gtgctggggt cgccctgtgt cccgtgcata
      181 ggagcatctc agcctccagg tcctctcctt tggggctcac ggcaccccca tgctacgaac
      241 cgcaggcagg gacggcctct gtcgcctgtc cacctacttg gaagaactcg aggctgtgga
      301 actgaagaag ttcaagttat acctggggac cgcgacagag ctgggagaag gcaagatccc
      361 ctggggaagc atggagaagg ccggtcccct ggaaatggcc cagctgctca tcacccactt
      421 cgggccagag gaggcctgga ggttggctct cagcaccttt gagcggataa acaggaagga
      481 cctgtgggag agaggacaga gagaggacct ggtgagggca ttgacaatgc ataaccattt
      541 gccgagcgtt cttccccgga ctgcatccgt ttagtctact gagaggcagc tcagcgttcc
      601 caaggagaca gatgtctagc tttgctcttt ctgtctgtgt gatgctggag aatcgatatg
      661 cccctgggcc tccatctcca tctgtaaaac aagggcatca ggcaagatcg gcagttctca
      721 tgttactata ccccacctgg tggcccgtcc tcacttggga accagtcaac atgccttctg
      781 gaagtctctc ttgtcactcc aagaaaagat ccccaggaaa cctacaggga ctatgtccgc
      841 aggaaattcc ggctcatgga agaccgcaat gcgcgcctag gggaatgtgt caacctcagc
      901 caccggtaca cccggctcct gctggtgaag gagcactcaa accccatgca ggtccagcag
      961 cagcttctgg acacaggccg gggacacgcg aggaccgtgg gacaccaggc tagccccatc
     1021 aagatagaga ccctctttga gccagacgag gagcgccccg agccaccgcg caccgtggtc
     1081 atgcaaggcg cggcagggat aggcaagtcc atgctggcac acaaggtgat gctggactgg
     1141 gcggacggga agctcttcca aggcagattt gattatctct tctacatcaa ctgcagggag
     1201 atgaaccaga gtgccacgga atgcagcatg caagacctca tcttcagctg ctggcctgag
     1261 cccagcgcgc ctctccagga gctcatccga gttcccgagc gcctcctttt catcatcgac
     1321 ggcttcgatg agctcaagcc ttctttccac gatcctcagg gaccctggtg cctctgctgg
     1381 gaggagaaac ggcccacgga gctgcttctt aacagcttaa ttcggaagaa gctgctccct
     1441 gagctatctt tgctcatcac cacacggccc acggctttgg agaagctcca ccgtctgctg
     1501 gagcacccca ggcatgtgga gatcctgggc ttctctgagg cagaaaggaa ggaatacttc
     1561 tacaagtatt tccacaatgc agagcaggcg ggccaagtct tcaattacgt gagggacaac
     1621 gagcctctct tcaccatgtg cttcgtcccc ctggtgtgct gggtggtgtg tacctgcctc
     1681 cagcagcagc tggagggtgg ggggctgttg agacagacgt ccaggaccac cactgcagtg
     1741 tacatgctct acctgctgag tctgatgcaa cccaagccgg gggccccgcg cctccagccc
     1801 ccacccaacc agagagggtt gtgctccttg gcggcagatg ggctctggaa tcagaaaatc
     1861 ctatttgagg agcaggacct ccggaagcac ggcctagacg gggaagacgt ctctgccttc
     1921 ctcaacatga acatcttcca gaaggacatc aactgtgaga ggtactacag cttcatccac
     1981 ttgagtttcc aggaattctt tgcagctatg tactatatcc tggacgaggg ggagggcggg
     2041 gcaggcccag accaggacgt gaccaggctg ttgaccgagt acgcgttttc tgaaaggagc
     2101 ttcctggcac tcaccagccg cttcctgttt ggactcctga acgaggagac caggagccac
     2161 ctggagaaga gtctctgctg gaaggtctcg ccgcacatca agatggacct gttgcagtgg
     2221 atccaaagca aagctcagag cgacggctcc accctgcagc agggctcctt ggagttcttc
     2281 agctgcttgt acgagatcca ggaggaggag tttatccagc aggccctgag ccacttccag
     2341 gtgatcgtgg tcagcaacat tgcctccaag atggagcaca tggtctcctc gttctgtctg
     2401 aagcgctgca ggagcgccca ggtgctgcac ttgtatggcg ccacctacag cgcggacggg
     2461 gaagaccgcg cgaggtgctc cgcaggagcg cacacgctgt tggtgcagct cagaccagag
     2521 aggaccgttc tgctggacgc ctacagtgaa catctggcag cggccctgtg caccaatcca
     2581 aacctgatag agctgtctct gtaccgaaat gccctgggca gccggggggt gaagctgctc
     2641 tgtcaaggac tcagacaccc caactgcaaa cttcagaacc tgaggctgaa gaggtgccgc
     2701 atctccagct cagcctgcga ggacctctct gcagctctca tagccaataa gaatttgaca
     2761 aggatggatc tcagtggcaa cggcgttgga ttcccaggca tgatgctgct ttgcgagggc
     2821 ctgcggcatc cccagtgcag gctgcagatg attcagttga ggaagtgtca gctggagtcc
     2881 ggggcttgtc aggagatggc ttctgtgctc ggcaccaacc cacatctggt tgagttggac
     2941 ctgacaggaa atgcactgga ggatttgggc ctgaggttac tatgccaggg actgaggcac
     3001 ccagtctgca gactacggac tttgtggctg aagatctgcc gcctcactgc tgctgcctgt
     3061 gacgagctgg cctcaactct cagtgtgaac cagagcctga gagagctgga cctgagcctg
     3121 aatgagctgg gggacctcgg ggtgctgctg ctgtgtgagg gcctcaggca tcccacgtgc
     3181 aagctccaga ccctgcggtt gggcatctgc cggctgggct ctgccgcctg tgagggtctt
     3241 tctgtggtgc tccaggccaa ccacaacctc cgggagctgg acttgagttt caacgacctg
     3301 ggagactggg gcctgtggtt gctggctgag gggctgcaac atcccgcctg cagactccag
     3361 aaactgtggc tggatagctg tggcctcaca gccaaggctt gtgagaatct ttacttcacc
     3421 ctggggatca accagacctt gaccgacctt tacctgacca acaacgccct aggggacaca
     3481 ggtgtccgac tgctttgcaa gcggctgagc catcctggct gcaaactccg agtcctctgg
     3541 ttatttggga tggacctgaa taaaatgacc cacagtaggt tggcagcgct tcgagtaaca
     3601 aaaccttatt tggacattgg ctgctgaatg gtcctatctg ctggctctcc cctgagatct
     3661 ggacagagga agatgggagg gtgctcatca cccccccagc ataatgatca gcctccttcc
     3721 tagagacaga ctcatgcaga ttgagatcaa aagtccctct gcttgggatc aaattaatgt
     3781 ttgacagagc tggccaggcg tggtggctca tgtatgtaat cctagcactt cgagaggccg
     3841 aggcaggtgg atcacgaggt caggagtttg agattagcct ggccaagatg gtgaaaccct
     3901 gtctctacta aaaataaaaa aaaattagcc aggcatggtg gcgggcacct gtagtcccag
     3961 ctactcagga ggctgaggca ggagaatcgc ttgaacccgg gaggtggagg ttgcagtgag
     4021 ccgagatcgc gccactgcac tccagcctgg gcgacagagt gggactccat ctcaaaaaaa
     4081 aaaaaaaaaa aa
//
