LOCUS       NM_001304533           20374 bp    mRNA    linear   PRI 07-APR-2024
DEFINITION  Homo sapiens sodium/potassium transporting ATPase interacting 3
            (NKAIN3), transcript variant 1, mRNA.
ACCESSION   NM_001304533 XM_005251216
VERSION     NM_001304533.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 20374)
  AUTHORS   Zhang,X., Kiang,K.M., Zhang,G.P. and Leung,G.K.
  TITLE     Long Non-Coding RNAs Dysregulation and Function in Glioblastoma
            Stem Cells
  JOURNAL   Noncoding RNA 1 (1), 69-86 (2015)
   PUBMED   29861416
  REMARK    Review article
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20374)
  AUTHORS   Bunyavanich,S., Schadt,E.E., Himes,B.E., Lasky-Su,J., Qiu,W.,
            Lazarus,R., Ziniti,J.P., Cohain,A., Linderman,M., Torgerson,D.G.,
            Eng,C.S., Pino-Yanes,M., Padhukasahasram,B., Yang,J.J.,
            Mathias,R.A., Beaty,T.H., Li,X., Graves,P., Romieu,I., Navarro
            Bdel,R., Salam,M.T., Vora,H., Nicolae,D.L., Ober,C., Martinez,F.D.,
            Bleecker,E.R., Meyers,D.A., Gauderman,W.J., Gilliland,F.,
            Burchard,E.G., Barnes,K.C., Williams,L.K., London,S.J., Zhang,B.,
            Raby,B.A. and Weiss,S.T.
  TITLE     Integrated genome-wide association, coexpression network, and
            expression single nucleotide polymorphism analysis identifies novel
            pathway in allergic rhinitis
  JOURNAL   BMC Med Genomics 7, 48 (2014)
   PUBMED   25085501
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 20374)
  AUTHORS   Carvill,G.L., Weckhuysen,S., McMahon,J.M., Hartmann,C.,
            Moller,R.S., Hjalgrim,H., Cook,J., Geraghty,E., O'Roak,B.J.,
            Petrou,S., Clarke,A., Gill,D., Sadleir,L.G., Muhle,H., von
            Spiczak,S., Nikanorova,M., Hodgson,B.L., Gazina,E.V., Suls,A.,
            Shendure,J., Dibbens,L.M., De Jonghe,P., Helbig,I., Berkovic,S.F.,
            Scheffer,I.E. and Mefford,H.C.
  TITLE     GABRA1 and STXBP1: novel genetic causes of Dravet syndrome
  JOURNAL   Neurology 82 (14), 1245-1253 (2014)
   PUBMED   24623842
REFERENCE   4  (bases 1 to 20374)
  AUTHORS   Gorokhova,S., Bibert,S., Geering,K. and Heintz,N.
  TITLE     A novel family of transmembrane proteins interacting with beta
            subunits of the Na,K-ATPase
  JOURNAL   Hum Mol Genet 16 (20), 2394-2410 (2007)
   PUBMED   17606467
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC023095.8, AC018861.9, AC090577.4, AC087358.9, AC091554.5 and
            AC120042.3.
            
            On Jan 30, 2020 this sequence version replaced NM_001304533.2.
            
            Summary: NKAIN3 is a member of a family of mammalian proteins (see
            NKAIN1; MIM 612871) with similarity to Drosophila Nkain (Gorokhova
            et al., 2007 [PubMed 17606467]).[supplied by OMIM, Jun 2009].
            
            Transcript Variant: This variant (1) encodes the longer isoform
            (1).
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR14038193.414613.1,
                                           SRR14038194.4181423.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA2154665, SAMEA2157437
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000623646.3/ ENSP00000501908.1
            RefSeq Select criteria :: based on manual assertion, conservation,
                                      expression, longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-274               AC023095.8         37345-37618         c
            275-412             AC018861.9         177815-177952
            413-493             AC090577.4         107722-107802       c
            494-691             AC087358.9         132879-133076       c
            692-752             AC091554.5         26079-26139         c
            753-823             AC120042.3         16619-16689
            824-20374           AC120042.3         28071-47621
FEATURES             Location/Qualifiers
     source          1..20374
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="8"
                     /map="8q12.3"
     gene            1..20374
                     /gene="NKAIN3"
                     /gene_synonym="FAM77D; NKAIN3-IT1; UG0898H09"
                     /note="sodium/potassium transporting ATPase interacting 3"
                     /db_xref="GeneID:286183"
                     /db_xref="HGNC:HGNC:26829"
                     /db_xref="MIM:612872"
     exon            1..274
                     /gene="NKAIN3"
                     /gene_synonym="FAM77D; NKAIN3-IT1; UG0898H09"
                     /inference="alignment:Splign:2.1.0"
     CDS             221..877
                     /gene="NKAIN3"
                     /gene_synonym="FAM77D; NKAIN3-IT1; UG0898H09"
                     /note="isoform 1 is encoded by transcript variant 1;
                     family with sequence similarity 77, member D;
                     sodium/potassium-transporting ATPase subunit
                     beta-1-interacting protein 3; NKAIN3 intronic transcript;
                     Na(+)/K(+)-transporting ATPase subunit beta-1-interacting
                     protein 3; Na+/K+ transporting ATPase interacting 3"
                     /codon_start=1
                     /product="sodium/potassium-transporting ATPase subunit
                     beta-1-interacting protein 3 isoform 1"
                     /protein_id="NP_001291462.1"
                     /db_xref="CCDS:CCDS94296.1"
                     /db_xref="GeneID:286183"
                     /db_xref="HGNC:HGNC:26829"
                     /db_xref="MIM:612872"
                     /translation="MGCCTGRCSLICLCALQLVSALERQIFDFLGFQWAPILGNFLHI
                     IVVILGLFGTIQYRPRYIMVYTVWTALWVTWNVFIICFYLEVGGLSKDTDLMTFNISV
                     HRSWWREHGPGCVRRVLPPSAHGMMDDYTYVSVTGCIVDFQYLEVIHSAVQILLSLVG
                     FVYACYVISISMEEEDTFDFIGGLDTHSYYQDHVELKPVKPVEISNDIEPEMRLLNLT
                     "
     exon            275..412
                     /gene="NKAIN3"
                     /gene_synonym="FAM77D; NKAIN3-IT1; UG0898H09"
                     /inference="alignment:Splign:2.1.0"
     exon            413..493
                     /gene="NKAIN3"
                     /gene_synonym="FAM77D; NKAIN3-IT1; UG0898H09"
                     /inference="alignment:Splign:2.1.0"
     exon            494..691
                     /gene="NKAIN3"
                     /gene_synonym="FAM77D; NKAIN3-IT1; UG0898H09"
                     /inference="alignment:Splign:2.1.0"
     exon            692..752
                     /gene="NKAIN3"
                     /gene_synonym="FAM77D; NKAIN3-IT1; UG0898H09"
                     /inference="alignment:Splign:2.1.0"
     exon            753..823
                     /gene="NKAIN3"
                     /gene_synonym="FAM77D; NKAIN3-IT1; UG0898H09"
                     /inference="alignment:Splign:2.1.0"
     exon            824..20374
                     /gene="NKAIN3"
                     /gene_synonym="FAM77D; NKAIN3-IT1; UG0898H09"
                     /inference="alignment:Splign:2.1.0"
     regulatory      20350..20355
                     /regulatory_class="polyA_signal_sequence"
                     /gene="NKAIN3"
                     /gene_synonym="FAM77D; NKAIN3-IT1; UG0898H09"
                     /note="hexamer: AATAAA"
     polyA_site      20374
                     /gene="NKAIN3"
                     /gene_synonym="FAM77D; NKAIN3-IT1; UG0898H09"
                     /note="major polyA site"
ORIGIN      
        1 gccagacgct cgggtcgtgc gcaccgcact gacctcggcc cgccccgccg ggaaactaac
       61 aaaggcgggc gcgagccccg agccctggag ccgcgagcgg cggccgcggg gccgaggagc
      121 ctgggccggg ccgggcgggg actactccgg agtcaggagg cagcagcggc ggaggacgag
      181 gatctctggc agtcagcgcc gctcggacgc cgccggcacc atgggctgct gcaccggacg
      241 ctgctcgctc atctgcctct gcgcgctgca gttggtctca gcattagaga ggcagatctt
      301 tgacttcctt ggtttccagt gggcgcctat tcttggaaat tttctacaca taatagttgt
      361 catattgggt ttgtttggga ccattcagta cagacctcga tacataatgg tgtatacagt
      421 gtggactgcc ctctgggtca cctggaatgt gttcattatc tgcttttatt tggaagtagg
      481 tggactctca aaggacaccg atctaatgac attcaatatc tctgtacatc ggtcatggtg
      541 gagagaacat gggcctggtt gtgtcagaag agtgctgcct ccctcagccc atggcatgat
      601 ggacgattac acgtacgtct ctgtcacagg ctgcatcgtt gacttccagt acctggaggt
      661 catccacagt gctgtccaaa tactactctc tttggtgggt tttgtgtatg cctgttatgt
      721 gatcagtatt tccatggaag aagaagacac atttgatttc ataggtggac ttgatacaca
      781 ctcctactac caggatcatg ttgagttaaa gcctgttaaa ccagtcgaaa taagtaatga
      841 cattgaacca gaaatgcggc tgctgaactt gacttaggga gcaaaggacc attgactgcg
      901 cgcctcggtg gatccgaccc gcctgacatt ccttccagag gctagactgt gcttcctggc
      961 tttcccacga atcatggagc attttggtca cagcctttgt attattagca ttgttctcta
     1021 gatgagttct aggtgcttgg gtgggtattt ttttagtcgt tttcttctta tatgaacact
     1081 tgtaagttgt aaaaaaaaaa aaaaaagaaa aaacagaatt tggttttaaa tttttaacaa
     1141 tatttaatgt gaggcatgca aaatgaaaaa gcaaatctgt gaaaaccttc tacagtcaat
     1201 tctaagagaa atctcagtgt gtgctgtgga gatgttaagt cagcactgct gactgttgaa
     1261 gttattctag gcctgatgaa tttgttttag cagacattac ctgtggttat cagccaccaa
     1321 ggtagaccct gtgacagctg ataaataggt acaaataatg gatccagctt ttggattgaa
     1381 tatgggtcat tttttcaaca gcataaaaca aaacatggag tcctcctttg ttcctgactt
     1441 cttaaaaccc agaacgatat tatggcaatc taaattttca gattcgtgca tatcttgttt
     1501 ttcctgatat atatatatat gtaggcacat ggaagagtaa aaggattagt agaacccctt
     1561 tcccctttgg agggaatatg ggtgtctctg aggtccatat tttctactca ttattccatt
     1621 cctgacactg ctgtcagacc taaacataca gctcatgggc ttgtgggaca gaaatcacaa
     1681 acatagacct gcagtcagga acttttctct taggatattc aaaagaagcc tgaaaatgct
     1741 gtagcattct ctataaatac ttctaaagga gacattcacg tgtgagcaac atcagctttt
     1801 ctttctccta ccccttccca ataaccaaga aaatgatatg ggaagcaatt atctgtggaa
     1861 aaaaggactg tcttgaaaac gcatcacagt tgtatttttt taactggcat aaaacttaca
     1921 tatggtaaaa tgcacaaata ttaatggtac gatttgatta gttttgaaaa atgtacatac
     1981 ccatgtaacc aaggcctcaa tcaaaatgca gaacatttcc gtcactttaa aaaattccct
     2041 tatgccctct ttcaggcaat gcctacattc tcacagacaa ccactgtgct aattttcatc
     2101 atcactgata atttggtctg ttctcaatat aaaatatata cacttttcac atcacttttg
     2161 cccacacttc tcaatcacta ttttttatat gaaaataagt tttgctcact ttgtgtaacg
     2221 accacagtga agctccctat aggccagaaa gttgtgaata tgtggttatt aactcagccc
     2281 atgcatctct aagaagtccg tctattaacc acctaaaact gttacaaata tttgtatgtg
     2341 tgtgaaagtc ttttttcttc ttgttcttct ttcggagcct ataggtttca tgagactctg
     2401 ttaagaatca gagtttaatg tgacaaagtt tgccttcatt cctccaagct catcacaacc
     2461 acagtgagcc atttggagac ctaatttact cactagcctc cagattttac ccctttaatc
     2521 cattggtacc cacaaactcc cattactttt ttttctgctt aataaatcca aattcaaata
     2581 aagaaaagct ggcagggacc ttgaagatgg tggaatccaa gccactattc tgcagatgag
     2641 ggggctgaag cctaagggat ttggtgaact tgtccagagc ctgtatctgt acacaggggc
     2701 aagagccata gccagtggac agagaacatg ggagcaaaag ttggggtttg ggtcccatcc
     2761 accaccatgt tcttggacag tgtttgccat ctctgcacta cagttttcct catcaatgaa
     2821 gtggaactat gatccctacc tcccaaaggt gaggtgagaa tttaacgaaa aatgtaaaaa
     2881 aattctcagt acacagtgaa gcactccaca attaaaggag gtgattatta ttaataatgt
     2941 caaaacactc ctctgtaccc tgtctggagc tcttgctttc cactcaagcg ctatgaagag
     3001 cccacagaaa caacaaactc tgttttttaa aaagcagctg ggaaaacctt gcccaagttt
     3061 aaatgatttg aaataaacta aaaaatgctt taatttaaaa ataacattaa tattcaagtt
     3121 ccaaaactaa tgccaataat tattgttagt attgttacga ttattgaaaa agctgataaa
     3181 acatcaaaac tgtagagagt cagtaaaaaa ggataaaatg agtattgaca tattttaaac
     3241 tgtcacttaa ttacccccac acatacacat gcaaataaaa tgtggttaac atttcacaaa
     3301 atagaaccat actaaatttt gtttctattt tatcttcacg tgaatttgta catagttcta
     3361 gtaggcactg cagagtctga acttagtcta agtgcagata acagctttga ggaaaaaatc
     3421 cttaccttag tgatttgtct atgaatattc aatgtaggca actatttaat atggtgtata
     3481 tgttttcatt tttaatcttt cttcacttaa atatgaagtt ataactgttt caatctccaa
     3541 cctcagcaat ccataaagat tgtcctaaca ttctggatat ttgccactca tcagaaacaa
     3601 gttagattga tctgccacct cctcttctct cttttcttct ccctgccttt catcttcctg
     3661 gtttctcttt gagggctatg cttctgtaag acaaagggaa aaaaagaagt gcagagttgt
     3721 acagtaatac ttggcaatta cccgttaatc tgggtaattc caatgaagta ctgtcacagt
     3781 tactgttcca tggaaatgag catttgcagt tattgctttt gcctccagtc ttatagaatg
     3841 cactctgcat tgtgcgtatc cagtagggtt ttcagcaaag acatggtcac tacatgcact
     3901 gtatgttctt gccaaacctc agcttctcca tatgcaattg tgtgtctggt cagagtaagg
     3961 gaaaatgaat gcatccctta gcttgcattc attggtcaga atcttaacta tcttaagaga
     4021 tggtgcagct ctagattcaa tagctctcct cagaagtggc cctggcaaaa ctgaagatag
     4081 gacatccact gctctttagc ttctagtgct gactggaatg gtgaacattt aaagccagtg
     4141 tttttcctct tggagccacc ttagcactga gtcttgtaaa ccttggccag cccttcctca
     4201 ggccgtgcct tctatcttgt gtgaatgatg catcctttct taagcgtctt ctgctgacct
     4261 cgtgcagcac cgcaggaagc tgggatgctt tcgagcttac tttttcttta tttgagcttc
     4321 tggtcatgtt tcaaagccat caaaatctaa gcaagggagt tacagggagg gttagagaat
     4381 taccaaagga cacaaaatgt cttgggttgt ggaatagcac acatcagaga aatctcaaac
     4441 atctcttagg aaaatctcta aatgtgtata tccccaagta tcttagcctt ccacctacca
     4501 cataaagtga gggtatgtgt ccctcaaatg agaaaaatga aaacacactt tcttaccact
     4561 tcaaatctgg gaggtggttg gctcatttgt tttgaagata ctcgacactt tgccctagca
     4621 aaatattgac ttctttgatt tttccttcag aaaaataagc cctgttattc ctatagacct
     4681 aaataaggga ggcagccagt ttcaagaggc tggctctaac aaaatatacc aaggctgtca
     4741 tctgtctcac ttaatgaatg ggaaactcct gattgagaag aatttgtctt cattaaaact
     4801 agctaaaatg tacattgcaa atctgaagaa aacaatcatg actctgctaa tttgagaagc
     4861 aaaaaccaaa atttctcttt tcaatctttg caaattaaaa aggaatcttg ccaagaataa
     4921 acaaatcttc atttcatacc taattttaaa acgaattgtg tccccaaata tggtctattc
     4981 tggctaatca ttttttaagc aaatcctcac ttactttttc tgagtcactt tagtatgtaa
     5041 ctaggataaa tttcatagtt gatcagaatg caaatgttct aacttgacat ttttgcccaa
     5101 gatacgttct ttccaggtat agctgaatta agtaggaaaa atataaataa ttgctctttt
     5161 aaaactataa caacttgaat gcctgcggtt ttatttccat ctaatttaaa agttatctgt
     5221 aacctttgtt tgatagaagg tctgttgaag tgtctaagaa ccatgttgaa atatttgtga
     5281 taaataggcc acaacttaag gatattatgc ccaaaagtga actgacagag gaaagtactc
     5341 ttcatataac tgcacagtga acaatttaga aagggaacag atgaccagac acagtggctc
     5401 atgcctgtaa tcccaaagct ttgggaagtt gagatgaaag aatcacttga ggccaggagt
     5461 tcaagaccag cttgggcaaa atagtgagac cgtatctcta caaaaacaaa caaataaaca
     5521 aaaaatacct aaaaaaaaat ttaaattagc caagcatggt ggcatgtacc tatgacccca
     5581 gccacttgag ggactgaggg aagggaagat tacttgagcc caggaattag aggctgcagt
     5641 gagtgcacta ctgcactcca gcctaggcaa tacagcaaaa gcctgtctct aaaaagagag
     5701 agagataagt agatatgttt taattattag aagaaggtat ttatcaataa agaattctca
     5761 aaaaaatgga attatcaaaa aattcaaaag ttatgggtag catctctttt tcatctgaaa
     5821 aagcttagtt tcttattgaa gactaaaaag aaaaatgcca cttcttgaag gtggatacag
     5881 cttcttaaat attggtattt gtagaaaaat ttggtggcag gcaaaacttg aatcatcttt
     5941 cttgaacttg cattcaaata aagggtaaaa atcatgttaa atgctaaaca tttttaaaaa
     6001 ctgaaatatt taaagaatcc aaaatatgct ttagcttaaa cttgagagct aagttaagta
     6061 aaaagaagaa aagaatagaa ggtagaaagg aagggagagg aaaatggaga gaagatgagg
     6121 aagagaaaga gaaagaaagg gaatggacaa ggagacagga aggaagaatc caaagttgaa
     6181 agtcacctaa ttgggatttg aacagtcagt ttttaactca gaattttgtt cttgtttctt
     6241 tgattgacta aaaacattga atcattttcc atgtaaggca tgtttttcct ttcctcttca
     6301 gagttattta gaaacagttc aaagaaacca ataatctatc catttcttct catagaattt
     6361 gctttggcag acaacttagt ctatattagt taggattagg tttacctaca agtaacagaa
     6421 aaagaaaaat gacaatggat taaataacat agaggtctat ttctcttttt atttcgaaat
     6481 tctggagaca gtcagcaaag agccggatgt gatttcccta gagacaagga ccgagactcc
     6541 tctcattgct tcatcctctg tggccgccat ttttaagacc ataacatgac tcaaaatggc
     6601 tgctgaagct tcagccattg gttttgtatt ctggccttgg aggtggagaa ggaacaaaag
     6661 gaatgtttct ttcctttaag gatatgcctc agaaatacac acactacttc tgtttacatc
     6721 tcattagcca aaacttggtc cacccccaac tttgcagtga agaaacctgg gtattatagt
     6781 ctttattctt aatgacttta tgcttaacta aaaagtaaga gctttgctgg acatggtggc
     6841 ttatgcctgt aatttcagca atttggaagg ccaaggcgtg cagatcactt gagcttacga
     6901 gttcgagacc agcctgagca acatggcaaa accccatacc tacaaaaaat acaaaaacca
     6961 gctgtggcgg tgtgtgccta tagtcccagc tacttgggag gttgaagtag gagggttgtt
     7021 tgaacctggg agacggaggt tgcagttagc caagatcatg ccactgcact ccaacctggg
     7081 agatggagcc aaaccttgtc tcaaaaaaaa agcggggggg gcttcattta ttagtaagaa
     7141 ggaaaaatat ttataaaatc atacttagca gtttcaatca cacagttcaa actaattgac
     7201 atgatttctt ggaacagtgt tttcatttgt agtactttat aacacattct agaaaaaatg
     7261 tacatatatt cttcagtact gtgagagatt taatcatcaa gtatgtgaaa tgagaatttc
     7321 tgcctcatct tgtttcctta tcttgtcttt gtggttagaa agaaatgaaa ataaatcagt
     7381 agcactacat ccttctaggt ttcccataat tttgcagaca ggtttagctt ttcttctcta
     7441 gaattgagtt taaaattcta gagccaatct aacattttgc ttggtcctca ttgtgctgcc
     7501 acaataaatt aattcttcta tggtcataac acttggctat tttattttgg tagggccttc
     7561 tcttctgaat tgattggtag tgttgttatt ttcttgttat tcagtttaac aagtacataa
     7621 tcaacatcag tgcttgggaa gtcaggagta cgagagataa ataagaagta tatgatcttt
     7681 tctcttattt tctctcagta taagttggac ctgtttttcc cttcatctct ttttcttcaa
     7741 gaacataata tcggctgaag tggaatgagt attcaaattg tccaaaaaaa tatacaagtg
     7801 agggaattaa taaaattttt tgtaattata aatatgtata tattgggggg caaaatatga
     7861 ctttttattt ttatttttaa ccaccagatt gagtatgttg atacatcaaa tgccagtctt
     7921 ttatcttcct agtttttcaa atagaaaagt gatactaaca tcaataatta aacttcccaa
     7981 gatttttttg tctctctctg aatcaagttc gtcgtctatt tacgtgcttc tcagttgaca
     8041 tttgtgaagg cagattatac acatgagaca gtggtgaata aatccacccc aaaattcctt
     8101 tgcagatctt gagtatttgc caatattctc tatgatttat ttacattctt ttttcatata
     8161 tatactttaa gttctgggat acatgtgcag aatgtgcagg tttgttacat aggtatacat
     8221 gtgccatggt ggtttgctgc acccatcaat tcatcatcta cattaggtat atctcctaat
     8281 gttatccctc cccttgtccc ccactcccca acaggccctg gtgtgtgatg ttcccctccc
     8341 tgtgcccata tgttctcatt gttcaactcc cacttaagag taagaatatg cagtgtttgt
     8401 tttttgttcc tgtgttagtt tgctgagaat gatggtttcc agcttcatcc atgtccctgc
     8461 aaaggacatt aactcatttt ttatggctgc atagtattcc atggtgtata tgtgccacat
     8521 tttctttatc cgttctaaca ttgatgggca tttgggttgg ttccaagtct ttgctattgt
     8581 gaatagtgct gcaataaaca taggagtgca tgtgtcatta tagtagaatg atttataatc
     8641 ctttgggtat acacccagta ggggattgct ggatcaaatg gtatttctag ttctagatcc
     8701 ttgaggaatt gccacactgt catccacaat ggttgaagta aattacactc ccaccaacag
     8761 tgttaaaagc attcctattt ctccacatcc tctccagcct ctgttgtatc ctttttaatg
     8821 atcgccattc taactggtgt gaggtggtat ctcattgtcg ttttgatttg catttctcta
     8881 atgaccagtg atgatgagat ttttttttac gtttgttggc tgcataaatg tcttctttta
     8941 agaagtgtct attcatatcc ttaacccact ttttgatgga gttgtttttt ttcttgtaaa
     9001 tttgtttaag ttccttgtag attctggata ttagcccttt gtcagatgga taggttgcaa
     9061 aaattttctc ccattctgta ggttgcctgt tcactctgat aatagtttct tttgctgcac
     9121 agaagctcct tagtttaatt agatcccatt tgtcaatttt ggcttttgtt gacattgctt
     9181 ttggtgtttc agtcatgaag tctttgccca tgcctgtgtc ctgaatggta ttgcttaggt
     9241 tttcttctag ggttttaatg gctttgggtt ttacatttaa gtttttaagc catcttgagt
     9301 taatttttgt acaagatgta aggaaggggt ccagtttcag ttttctgcgt atggctagct
     9361 aattttccca gcaccattta ttaaatagga aatcctttcc ccattgcttg tttttatcag
     9421 gtttgtcaaa gatcagatgg ttgtagatgt gtggtgttat ttctgaggcc tctgttctgt
     9481 tgcattggtc tatatatctg ttttagtaaa agtaccatgt tgttttggtt actgtagcct
     9541 tgtagtatag tttgaagtta ggtagcatga tgcctccagc tttgttcttt ttgcttagga
     9601 ttgttttggc tatatgggct ctttttggtt ccctatgaaa tttaaagtag ttttttctaa
     9661 ttctgtgaag aaaatcaatg ttagtttgat gggaatagca ttgaatctat aaattacttt
     9721 gggcagtatg gccattttta caatattgat tcttcctatc catgagcatg gaatgttttt
     9781 ccatttgttt gtgtcctctc ttatttcctt gagcagtggt ttgtagttct tgaagaggtc
     9841 attcacatcc cttgtaagtt gcattcctag gtattttatt ctctttgtag caattgtgaa
     9901 tgggagtttg ttcatgattt ggctctctgt ttgtctatta ttggtgtata ggaatgcttg
     9961 tgatttttgc acattgattt tgtatcctgc aactttgctg aaattgctta tctctttaag
    10021 gagttttggg gttgagacaa tggggttttc taaatgtaca accatatcat ctgcaaacag
    10081 agataatttg actttctctc ttcctattcg aatacgcttt atttcattct cttgcctgtt
    10141 tgccctggcc agaacttcta atactgtgtt gaataggagt ggtgagacaa gccacccttg
    10201 tcttgcgcca gttttcaaag ggagtgcttc cagtttttgc ccattcagtg tgatattggc
    10261 tgtgggtttg tcataacagc tcttattatt ttgagatatg ttccatcaat acctagttta
    10321 ttgagtgttt ttagcatgaa ggagggttga attttgtcga aggccttttc cgcatctatt
    10381 gagataatca tgtggttttt gtcattggtt ctgtttatgt gatggattac attcattcat
    10441 ttgcatatgt tgaaacagcc ttgcatccca gggatgaagc tgacttgatc atggtgggta
    10501 agctttttaa tgtactgctg catttctttt gccagtgttt cattggggat tttcacatag
    10561 atgttcatca gggatattgg cctgaaattt tcattttttg ttgtgtctct gcctgggatt
    10621 ggtatcagaa tgatgctggc ctcaaaatat gagttaggga ggagtctgtc ttttctactg
    10681 tttggaatag tttcagaagg aatggtacca gctcctcttt gtaactctgg tagagttcag
    10741 ctatgagtcc atctggtcct gggctttttt ttttagttgg tcagctatta attactgcct
    10801 caatttcaga acttgttatt ggtctattca gggattcaac ttcttcctgg gttagtcatg
    10861 gtagggtgaa tgtgtccagg aatttatcca tttcttctaa attttttagt ttatttggat
    10921 agagttgttt gtaatattct ctgacggtag tttgcatttc tgtgggatta gtggtgatct
    10981 ccactttatc actttttatt gtgtctattt gattcttccc tcttttcttc tttattagcc
    11041 tggctagcca tctaagtatt ttgttaatct tttcaaaaaa ccatctcctg tattcattga
    11101 ttttttgaag ggtttttcgt atctctttca gttctgttct gatcttagtt atttcttgtc
    11161 ttctgctagc ttttgaaata gtctgctctt gtttctttaa ttcttttaat tgtgatgtta
    11221 gcgtgttgat tgtagatgtt tagattttag atgtttagat gtttcccact ttctcctgtg
    11281 agcacttagg tctataaatt tccttctaag cactccctct aagctctatc ccagagattc
    11341 tggtacattg tgtctttgtt cttgttggtt tcaaagaact tatttatttc tgctgtgatc
    11401 tcattatttt cccaggagtc attcagaagc aggttgttca gtttccatgt agttgtgtgg
    11461 ttttgagtga gtttcttaat cctgagttct aacttgattg cactgtggtc tgagagactg
    11521 tttgttatgg ttttcattct tttgcatttg ctgatgagtg ttttacttcc agttatgtgg
    11581 tcgattttag gaaaatgtgc tatgtgatgc tgaggagaat gtatattctg ttgatttggg
    11641 gtggagagtt ctgtagatat ctattaggtc tgcttggtca agaggtgagt tcaagtcctg
    11701 aatatccttg ttaattttct atctcggtga tctgtctaat acacacaatg gagtgttaaa
    11761 gtctcccact attattgtgt ggtagtctaa gtctctttgt aggtctctaa gaacttgctt
    11821 tatgaatctg ggtgctccac tattaggtgc atacatattt aggatagtta gctcttcctg
    11881 ttgcattgat ccttttacta ttatgtaatg gccttctgtg tctgttttga tttttgttgg
    11941 cttaaagtct gttttaccag aggctaagat tgcaacccct gctttttttt gctttccatt
    12001 tgcctggtaa atatctctcc atccttttat tttgagccta tgtgtgtctt tgcacatgag
    12061 atgggtctcg aatacaacac accaatgggt tttgactctt tatccaattt gccagtctgt
    12121 gccttttaat tggggcattt agcccattta catttaaggt taatattgtt atgtgtgaat
    12181 ttgattctgt cattatgatg atagctggtt attttgccca ttagttgatg cagcttcttc
    12241 atagtgtcga tggtctttac attttggaat gtttttgcag tggctggtac tggttgttcc
    12301 tttccatatt tagtacttct ttcagaagct cttgtaaagg caggcttggt gtgacaaaat
    12361 tcctcagcat ttgcttgtct gtaaaggatt ttatttctcc ttcacttgtg aagctcagtt
    12421 tggctggata tgaaattctg ggttgaaaat tcttttcttt aagaatgttg aatattagcc
    12481 cccaatctct tgtggctttt agggtttctg cagagagatc tgctgttagt atgatgggct
    12541 tccctttgta ggtaacccaa cttttctctc tggctgccct taacattttt tctttcagtt
    12601 caaccttggt gaatctgacg attatgtgtc ttggggttgc tcttctcaaa gagtatcttt
    12661 gtggtgttct ctgtatttcc tgaatttgta ttctgtattt cctaagcctg ccttgcgagg
    12721 ttggggaagt tctcctggat tatatcctaa attgtgcttt ccaacttgat tccattctcc
    12781 ccatcacttt taggtacacc aatcaaacgt tggcttggtc ttttcacata gtcccatatt
    12841 tctgagaggt tctgttcatt ccttttccat ttttttcttc taatcttgtc ttcatgcttt
    12901 atttccttaa gttgatcttc agtctctgat atcctttctt ctgcttgatc gattcagcta
    12961 ttgatacttg tgtatgcttc atgaagttct cgtgctgtgt ttttcagctc catcaggtca
    13021 tttgtgttct tctctaaact ggttattctc taaactggtt attctagtta gcaattcctc
    13081 taacctttta tcaaggttct tagcttcctc gtattgggtt actatatgtt ccattcgctc
    13141 tgaggagttc gttattaccc atcttctgaa gcttacttct gtcaatttgt caaacacatt
    13201 ctccattcag tattgttccc ttgctggtaa ggagttgtga tcctttggag gagaagaggc
    13261 gttctggttt tgggaatttt cagccttatt ggactggttt ttcctcatct ttgtggcttt
    13321 atctaccttt ggtctttggc attggtgacc tttggaagga gtgtttacat ggtcatgctc
    13381 tttgttgatg ttgatgctat tgctttctgt ttgttaattt tctttctaac agtcaggccc
    13441 ttcttctgct ggtctgctgg agttttctgg gggtccactc cataccctgt ttgcatgggt
    13501 atcaccagca gaggctgcag aacagcaaag attgctgcct cctcctactt ctggaagctg
    13561 tgtcccagag gggcacctgc cagatgctag ccagagctct cctgtatgaa gtgtctgtcg
    13621 acccctgttg ggagatgtct ccccatcagg aggcatgggg gtcagggacc cacttgtgga
    13681 agcagtctgt cccttagcgg agctccagtg ctgtgctagg agatctgctg ctctcttcag
    13741 agctggcagg tgggaatgtt taagtctgct gaagctgcgc tcacagctgc cccttccccc
    13801 aggtgctctg tccccaggag atgggagttt tatctataag cccctgacta gggctactgg
    13861 ctttctttca gagatgccct gcccagagag gaggaatcta gagaggcagt ctggcttcag
    13921 tggctttgca gcgctgcagt gggctccact cagactgaac ttcctggcag ctttgtttac
    13981 actgtgaggg gaaaactgcc tactcaagcc tcagtaatgg cagatacctc tcccccaacc
    14041 aagcttgagc atcccaggtc tacttcagac tgctgtgctg gaagtaagaa tttcaatcca
    14101 gtggatctta gctttctggg ctccatgggg gtgggatcta ctgatcaaga ccacttggct
    14161 ccctggtttc agcccccttt ccaggggagt gaatggttct gtctctctgg cattccagac
    14221 aactctgggg tacgaaaaaa actcctacag ctagctcagt gtctgcccaa atggccactc
    14281 agttttgtgc ttgaaatcca gggcccttgt ggtgtaggca cccaagggat ctccttgtct
    14341 gtggattgcg aagaccatgg gaaaagcgta gtatctggac cggagtgcac ccccactcac
    14401 ggcatggtcc ctcatggctt cccttggcta ggggagggag ttccccaacc ccttgcactt
    14461 cccaggtgag gcaatgcccc accctgcttc tgcttgccct ccgtgggctg cacccactgt
    14521 ctaaccagtc ccagtgagat gaaccgagta cctcagttgg aaatgcagaa atcacccact
    14581 ttctgtgttg gtcttgctgg gagctgcaga cagctgttcc tattcggcca tcttgcctgg
    14641 gaatctgtaa ttatatttta ttgcatattc ttcctaggct gggtgtgtgt gtgtgaaaga
    14701 gagagagaaa cagaaacaga gacaaggaga cagagacagt gaaacagaaa cagagtcatc
    14761 ttccaggttc tacttattaa gcaatatccc atgaagtagc tgaaaagtgt tatattctcc
    14821 taatacctag tgtttgcaaa tctggcagct gtcactgatg atttaaacaa gattgggtga
    14881 cttatttatg tacacacaca tccacaatca aacttcaaca gtcgagtgta cccttttcta
    14941 aataatcacg ttgctaaaat gtgccacatg gcccatttct ttaaacaata aatggtaaat
    15001 tattattttg gggagtgaaa gctaaaagaa ataatatgtc taatacgatg tggcattttc
    15061 tctatacagt acagttttag cattgaaaag gacctcagca attccatttg ccccgttttc
    15121 agatgaggag attgaggctg gtagttacag tggttttgct tcatgtccca tcccactggg
    15181 gctgctatgc aagctctcag tctagtcttc tttcctctgc acttggtggc catcagctgt
    15241 aacaagtcct gactagacaa gggctttgtt gttgactaca attcaatgcc ttttttgcct
    15301 gcgtttgttt ggaccctgct aatcaaggct acagggcagc tgcagaaaga cacctgctat
    15361 tggcttacct gctcctcgcc ttccctctgc ttgggtctga gcatcagaaa gccaccttcc
    15421 agtgggtctt tgcctagctt ttgtcttgtc tttgcttttt attcatcttt gcttttgtct
    15481 tctcagggca aataggaaat cctagacctc agatcactgt tctttgcttc ccaaaagaca
    15541 gaacagctca gtcctggctg ccaccttctt tctttactct tggtttaaat gtaatcccac
    15601 atgccctaga caagcctcct gatgattttt catcaaacat gaaaatagct tacttttaac
    15661 tgctgggtgt cagtctcttc taaaaatttt gttcctaagg aattgatttt gcaaatcagt
    15721 gctaaagtca ctttttaact gcctcacata ctatcatttc tttgacaatt ctttttaaag
    15781 gggattgctc ttttctcctt ctggtttctc aaatctactt ttaacttcaa atagcaggca
    15841 tgcaatgtag ttttataaga taatatacta ggaccatcta tcagatatga aaccaagcat
    15901 aatcattgca attatttcta ctgtattcag ataatgataa tacaaataag agtacgacat
    15961 acgtaaatgt tgattagctt tctggttcct tcatcaaaac ttgcgttgtg ttgtgcagcc
    16021 ttttctttgc attgtccagg ggttttgtta ttacaaacca taatatttaa cccatttctt
    16081 ctactaatat cttttaatat ttatgctatt atatagcttt ttatttttga catgtatcta
    16141 aaccagaaaa aaatattcct tgtacatgat atttttaggc aaaacataat gtctggagca
    16201 ccaagtgaaa taactgtgga gaatggaatg ttggacaatt tgtgtggcat gcttagctta
    16261 atttgtttct atggcacaag caaagctcat taattccatt tattatttta agccacttgt
    16321 ttggtgttat ggattttaag aatcagttgg tgttagaatt tttaataaca cagagaaagc
    16381 cattgaatat ggaactcaaa ttatctaagg tttacccaga agtcaaaatc acctggccct
    16441 ctgtaaattt ctctttgtgt tcctaggccc acaaagtctt tggtctgaag actcagagct
    16501 taaattgcat tggtcctgtt aatctttgtc aaaaaggaag tttgggcggc agtttcaggg
    16561 tagtgttgag aagataactc ctggtcccat tttattcttt cctcatttgt tcagtgctca
    16621 tggccatcta caaccttcct tgattctatt ctgcctaagc ctcttatttc cacatctata
    16681 agtatagtgc tacataataa ttacaacctt taagaaaatg gagagttttc attaaagggc
    16741 ccctgcaaat ctatgatgct agatgacaga ttctaccaga aggccagagt attaatagca
    16801 cccgtgataa ctgtaataag aatatgtctc gttttctttt aaagacatag atattccatt
    16861 ttaatcctgt ataactcaaa gaaaatttgg gtgttaacac tttgaaatac ctttacctcc
    16921 tttgggggaa atccaaactg aaaggaatta atatccacat cagttcctaa agcaaaatgc
    16981 ctgacacaga ctaacaaagc tctttctcat cctgtggtag gaacttagga gtgataactc
    17041 acattgagaa cttgtgatct gaaagcacta aggaatttct gccattgcag gtaggaaaaa
    17101 aaaagacaaa aatggtattc tcaggtgagc ttacctttca aatttttctg agacttccta
    17161 aatgtgacaa gaactctgct gtgtggcaac cttatgtatc cacaacagaa ctaaggaccg
    17221 aaaaaaaaaa aaaaaagatc tctatcccaa tagattttat aaaatccata ctctaaaact
    17281 cctgagtttt acatgtaccc taaaacttaa agtatagtaa aaaaaagaaa agaaagaaaa
    17341 actctttaac cctttgttta aatcctatta actcttaacg atacacagtt cgaattatct
    17401 aaatgaaata attttcaagc acataacaga ttagaaacag agaatgagaa aggtatagta
    17461 gatattatgt aaataagcag aaataatggc aataattaaa cacactatct ctacctaaaa
    17521 gaacagagat agaaaactca tataaaaatc taaactacag ttttatgggg atagttaagg
    17581 taagagcctg caggcagcac tgtattgctt tacaaaacag catttcattt gtattatgat
    17641 gatttcagac tatcaattta aaaattcatt agtataaatt aagaacaggt accattttct
    17701 ccagatactt ccccttcatc tgtcctgaaa ttattaatta ttgacttcta cttaaataag
    17761 atcttatttt catctgctgg aaaacttttt ctgataacca tacatatctt caatgtctac
    17821 aatttgaatg gagagccctt tcaatgtggc gtttctgttt cttccataac ctcacaacga
    17881 tatgtggtgg ccccgcagtc attatggtct tgttaaataa ttagatttgt gtaaactata
    17941 ttttagagtc ttccaaaacg cctctccttc caaaatggct aaaagggcaa agcgtcagta
    18001 attctgtaga catgcttcat gcatgttctg aataggagct atggtataat gagatgctat
    18061 ctctggaaaa aaatgaatag attttcaaga ttgtgagtcc tgacatgagt tctctagaat
    18121 tttccccttt gataaatttt cctttaccta gctgttgcca aattgtctct tctagaagaa
    18181 tgcccagatt ttttttcagt tccaaagtta tcaaaatccc aggaatattt cacagaaaag
    18241 agaagcattt atagcaagca tgggtgtggc atgctttctc tgtgggaagt tgtcatcctc
    18301 cacaagatct tgcccacact caaaacaaac ttgcttccca tcacattctt ggtttgtcag
    18361 cactctgtaa aaggaaatct catctcctgt ctgttgatag tagagcttat atcaaactgg
    18421 gacatgtttc ttcttcattc atgaataagt ctaattttct ctccggtgtg taaaactgac
    18481 aatacccaca agatactact gacttggaag tttcactgca ggtagctacc ataccagcat
    18541 ttggtaaact agctccctag gtgagacagc attagatgac ctccttcgtg ccacactact
    18601 tgccagtatc cactgggaga caaattatga ttgttgcgtc cttctttgaa aacacccctg
    18661 ctgagtacct actgtatgtg agtcactgtg caggcactag aaatataaag caaaaaaaac
    18721 agattctacc caccgggagc tcctagtcca gtggtgaaga ggtgtattaa ccctcaaggc
    18781 cctaagaaaa tccccaatag ggctctgcac aagccgggct ctgataggag gtgccagtgc
    18841 ttttcttctt ccagtttcag agccccagcg atcccaggat gaaggagagc ccatttgcaa
    18901 ccctcttctg tctccctaag cattcaacaa acacttagtg accatctgtc ttgtgcaaaa
    18961 agcttgggga gtgataaaaa caaatcaaat tcacatttta atttagggag tttaggagat
    19021 acatcctagt gtggatttca catggtcaat gatttgcttt ccttgaattt gccctctgca
    19081 accaacacct gttcgtgcta tgagactgaa gtcctcctag accgccccat tcatctgagt
    19141 agttagggct ctggatgaag gagcaaatgg acaaaataag ccccctcttg ctcaggacct
    19201 gactaacatt tcagaactgc ggtcacccat tttatacaaa ccaaagcact tctgacagac
    19261 ctctgaattt gcattaaaaa gagcacgtct acagctccta acaatcaaaa acaactatga
    19321 acactgcttg cttcagtgat acaaacagac attttcttgt tacatgtgtg gtgatctgag
    19381 aatggtgact ttggacccag tttgactggt tagcgtttaa ataaaactta acagactagg
    19441 caactaaagg aactcagtaa aagatcaaaa gcaatgctca aagggagtgc ctgggtaacc
    19501 atgatgtaat tgcagattga cacatctttg ggtttttcat tattgtttct aaaaactaga
    19561 tattattgct ttattattat gttgatgatg attattgaaa gcacgatagc aatgtttaag
    19621 tggtgagaat gactctaagc ctctttttgt tgctgtgact gacagaacta aagggagttt
    19681 gctctcacat tcacaatacc aactctgcca tcttatggaa aatattggaa gtacctaggg
    19741 catttcatta tatttcaaag gcacaggttg ctggtaagag ggacagaaag acaagaacat
    19801 agtaccttct atttctacta catgttttta atctttaaca tttttaccag cagaaatcat
    19861 ttttttttta aatctctcaa tcttcaaata attcttagat tgcttgccag caaagatgtc
    19921 tcttgatctt gacactggaa ttcaatgtaa aaatcttgaa tgatattttg tactgatatg
    19981 aatttctact gtcccataac actgtgtagt gacttcactg tatattaact tcttttctac
    20041 agatgtttga cttatgagat gaattaattg aaaaagtcaa agcctatcag gagctatctt
    20101 atatgatgtt ggtagcctgt gaaaaaataa atgtcttttt tcttatacaa actgataaca
    20161 agacttgctt tcacaattac tatttacatt tttgtgcata taatgcctgt atattatact
    20221 catatttgaa agtgatcaga aagtgttatt taacagaaac tacatacatt ttttatgtct
    20281 ctctggaccc tttgattcta agtaaattta cagtaagtta gcagtaatag actattcttt
    20341 tcaactatga ataaaaatgt acactgaagt acaa
//
