LOCUS       NP_056284                247 aa            linear   PRI 27-APR-2025
DEFINITION  protein NipSnap homolog 3A isoform 1 [Homo sapiens].
ACCESSION   NP_056284
VERSION     NP_056284.1
DBSOURCE    REFSEQ: accession NM_015469.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (residues 1 to 247)
  AUTHORS   Morgenstern,M., Peikert,C.D., Lubbert,P., Suppanz,I., Klemm,C.,
            Alka,O., Steiert,C., Naumenko,N., Schendzielorz,A., Melchionda,L.,
            Muhlhauser,W.W.D., Knapp,B., Busch,J.D., Stiller,S.B.,
            Dannenmaier,S., Lindau,C., Licheva,M., Eickhorst,C., Galbusera,R.,
            Zerbes,R.M., Ryan,M.T., Kraft,C., Kozjak-Pavlovic,V., Drepper,F.,
            Dennerlein,S., Oeljeklaus,S., Pfanner,N., Wiedemann,N. and
            Warscheid,B.
  TITLE     Quantitative high-confidence human mitochondrial proteome and its
            dynamics in cellular context
  JOURNAL   Cell Metab 33 (12), 2464-2483 (2021)
   PUBMED   34800366
REFERENCE   2  (residues 1 to 247)
  AUTHORS   Buechler,C., Bodzioch,M., Bared,S.M., Sigruener,A., Boettcher,A.,
            Lapicka-Bodzioch,K., Aslanidis,C., Duong,C.Q., Grandl,M.,
            Langmann,T., Dembinska-Kiec,A. and Schmitz,G.
  TITLE     Expression pattern and raft association of NIPSNAP3 and NIPSNAP4,
            highly homologous proteins encoded by genes in close proximity to
            the ATP-binding cassette transporter A1
  JOURNAL   Genomics 83 (6), 1116-1124 (2004)
   PUBMED   15177564
REFERENCE   3  (residues 1 to 247)
  AUTHORS   Lee,A.H., Zareei,M.P. and Daefler,S.
  TITLE     Identification of a NIPSNAP homologue as host cell target for
            Salmonella virulence protein SpiC
  JOURNAL   Cell Microbiol 4 (11), 739-750 (2002)
   PUBMED   12427096
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            HY046409.1 and BC005935.1.
            
            Summary: NIPSNAP3A belongs to a family of proteins with putative
            roles in vesicular transport (Buechler et al., 2004 [PubMed
            15177564]).[supplied by OMIM, Mar 2008].
            
            Transcript Variant: This variant (1) represents the longer
            transcript and encodes the longer isoform (1).
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR3476690.934110.1,
                                           SRR3476690.542599.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1965299, SAMEA1966682
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000374767.5/ ENSP00000363899.4
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..247
                     /organism="Homo sapiens"
                     /db_xref="taxon:9606"
                     /chromosome="9"
                     /map="9q31.1"
     Protein         1..247
                     /product="protein NipSnap homolog 3A isoform 1"
                     /note="protein NipSnap homolog 3A; protein NipSnap homolog
                     4; target for Salmonella secreted protein C"
                     /calculated_mol_wt=28336
     Region          37..136
                     /region_name="NIPSNAP"
                     /note="pfam07978"
                     /db_xref="CDD:429767"
     Site            48
                     /site_type="acetylation"
                     /note="N6-acetyllysine.
                     /evidence=ECO:0007744|PubMed:19608861; propagated from
                     UniProtKB/Swiss-Prot (Q9UFN0.2)"
     Region          146..245
                     /region_name="NIPSNAP"
                     /note="pfam07978"
                     /db_xref="CDD:429767"
     Site            166
                     /site_type="acetylation"
                     /note="N6-acetyllysine.
                     /evidence=ECO:0007744|PubMed:19608861; propagated from
                     UniProtKB/Swiss-Prot (Q9UFN0.2)"
     CDS             1..247
                     /gene="NIPSNAP3A"
                     /gene_synonym="HSPC299; NIPSNAP4; TASSC"
                     /coded_by="NM_015469.3:111..854"
                     /note="isoform 1 is encoded by transcript variant 1"
                     /db_xref="CCDS:CCDS6760.1"
                     /db_xref="GeneID:25934"
                     /db_xref="HGNC:HGNC:23619"
                     /db_xref="MIM:608871"
ORIGIN      
        1 mlvlrsaltr alasrtlapq mcssfatgpr qydgifyefr syylkpskmn eflenfekna
       61 hlrtahselv gywsvefggr mntvfhiwky dnfahrtevr kalakdkewq eqflipnlal
      121 idkqeseity lvpwcklekp pkegvyelat fqmkpggpal wgdafkravh ahvnlgytkl
      181 vgvfhteyga lnrvhvlwwn esadsraagr hkshedprvv aavresvnyl vsqqnmllip
      241 tsfsplk
//
