LOCUS       NM_173165               6328 bp    mRNA    linear   PRI 01-JUL-2024
DEFINITION  Homo sapiens nuclear factor of activated T cells 3 (NFATC3),
            transcript variant 1, mRNA.
ACCESSION   NM_173165
VERSION     NM_173165.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 6328)
  AUTHORS   Wang,H., Shi,Y., Zhou,X., Zhang,L., Yang,A., Zhou,D. and Ma,T.
  TITLE     HNRNPA2B1 stabilizes NFATC3 levels to potentiate its combined
            actions with FOSL1 to mediate vasculogenic mimicry in GBM cells
  JOURNAL   Cell Biol Toxicol 40 (1), 44 (2024)
   PUBMED   38862832
  REMARK    GeneRIF: HNRNPA2B1 stabilizes NFATC3 levels to potentiate its
            combined actions with FOSL1 to mediate vasculogenic mimicry in GBM
            cells.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6328)
  AUTHORS   Yang,F., Ma,Q., Huang,B., Wang,X., Pan,X., Yu,T., Ran,L., Jiang,S.,
            Li,H., Chen,Y., Liu,Y., Liang,C., Ren,J., Zhang,Y., Wang,S., Li,W.
            and Xiao,B.
  TITLE     CircNFATC3 promotes the proliferation of gastric cancer through
            binding to IGF2BP3 and restricting its ubiquitination to enhance
            CCND1 mRNA stability
  JOURNAL   J Transl Med 21 (1), 402 (2023)
   PUBMED   37340423
  REMARK    GeneRIF: CircNFATC3 promotes the proliferation of gastric cancer
            through binding to IGF2BP3 and restricting its ubiquitination to
            enhance CCND1 mRNA stability.
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 6328)
  AUTHORS   Zhang,X., Duan,X.J., Li,L.R. and Chen,Y.P.
  TITLE     lncRNA NEAT1 promotes hypoxia-induced inflammation and fibrosis of
            alveolar epithelial cells via targeting miR-29a/NFATc3 axis
  JOURNAL   Kaohsiung J Med Sci 38 (8), 739-748 (2022)
   PUBMED   35708150
  REMARK    GeneRIF: lncRNA NEAT1 promotes hypoxia-induced inflammation and
            fibrosis of alveolar epithelial cells via targeting miR-29a/NFATc3
            axis.
REFERENCE   4  (bases 1 to 6328)
  AUTHORS   Tong,Y., Zhang,Z., Cheng,Y., Yang,J., Fan,C., Zhang,X., Yang,J.,
            Wang,L., Guo,D. and Yan,D.
  TITLE     Hypoxia-induced NFATc3 deSUMOylation enhances pancreatic carcinoma
            progression
  JOURNAL   Cell Death Dis 13 (4), 413 (2022)
   PUBMED   35484132
  REMARK    GeneRIF: Hypoxia-induced NFATc3 deSUMOylation enhances pancreatic
            carcinoma progression.
            Publication Status: Online-Only
REFERENCE   5  (bases 1 to 6328)
  AUTHORS   Liu,X., Guo,J.W., Lin,X.C., Tuo,Y.H., Peng,W.L., He,S.Y., Li,Z.Q.,
            Ye,Y.C., Yu,J., Zhang,F.R., Ma,M.M., Shang,J.Y., Lv,X.F.,
            Zhou,A.D., Ouyang,Y., Wang,C., Pang,R.P., Sun,J.X., Ou,J.S.,
            Zhou,J.G. and Liang,S.J.
  TITLE     Macrophage NFATc3 prevents foam cell formation and atherosclerosis:
            evidence and mechanisms
  JOURNAL   Eur Heart J 42 (47), 4847-4861 (2021)
   PUBMED   34570211
  REMARK    GeneRIF: Macrophage NFATc3 prevents foam cell formation and
            atherosclerosis: evidence and mechanisms.
REFERENCE   6  (bases 1 to 6328)
  AUTHORS   Masuda,E.S., Liu,J., Imamura,R., Imai,S.I., Arai,K.I. and Arai,N.
  TITLE     Control of NFATx1 nuclear translocation by a calcineurin-regulated
            inhibitory domain
  JOURNAL   Mol Cell Biol 17 (4), 2066-2075 (1997)
   PUBMED   9121455
REFERENCE   7  (bases 1 to 6328)
  AUTHORS   Rao,A., Luo,C. and Hogan,P.G.
  TITLE     Transcription factors of the NFAT family: regulation and function
  JOURNAL   Annu Rev Immunol 15, 707-747 (1997)
   PUBMED   9143705
  REMARK    Review article
REFERENCE   8  (bases 1 to 6328)
  AUTHORS   Hoey,T., Sun,Y.L., Williamson,K. and Xu,X.
  TITLE     Isolation of two new members of the NF-AT gene family and
            functional characterization of the NF-AT proteins
  JOURNAL   Immunity 2 (5), 461-472 (1995)
   PUBMED   7749981
REFERENCE   9  (bases 1 to 6328)
  AUTHORS   Masuda,E.S., Naito,Y., Tokumitsu,H., Campbell,D., Saito,F.,
            Hannum,C., Arai,K. and Arai,N.
  TITLE     NFATx, a novel member of the nuclear factor of activated T cells
            family that is expressed predominantly in the thymus
  JOURNAL   Mol Cell Biol 15 (5), 2697-2706 (1995)
   PUBMED   7739550
REFERENCE   10 (bases 1 to 6328)
  AUTHORS   Vacca,A., Farina,M., Maroder,M., Alesse,E., Screpanti,I., Frati,L.
            and Gulino,A.
  TITLE     Human immunodeficiency virus type-1 tat enhances interleukin-2
            promoter activity through synergism with phorbol ester and
            calcium-mediated activation of the NF-AT cis-regulatory motif
  JOURNAL   Biochem Biophys Res Commun 205 (1), 467-474 (1994)
   PUBMED   7999066
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from BU849493.1, BC001050.2,
            AC020978.10 and CA418693.1.
            This sequence is a reference standard in the RefSeqGene project.
            
            On Nov 22, 2018 this sequence version replaced NM_173165.2.
            
            Summary: The product of this gene is a member of the nuclear
            factors of activated T cells DNA-binding transcription complex.
            This complex consists of at least two components: a preexisting
            cytosolic component that translocates to the nucleus upon T cell
            receptor (TCR) stimulation and an inducible nuclear component.
            Other members of this family participate to form this complex also.
            The product of this gene plays a role in the regulation of gene
            expression in T cells and immature thymocytes. Several transcript
            variants encoding distinct isoforms have been identified for this
            gene. [provided by RefSeq, Nov 2010].
            
            Transcript Variant: This variant (1) encodes the longest isoform
            (1).
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1163655.672167.1,
                                           SRR1660807.4102.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1965299, SAMEA1966682
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000346183.8/ ENSP00000300659.5
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-278               BU849493.1         5-282
            279-3992            BC001050.2         1-3714
            3993-6310           AC020978.10        111815-114132       c
            6311-6328           CA418693.1         18-35               c
FEATURES             Location/Qualifiers
     source          1..6328
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="16"
                     /map="16q22.1"
     gene            1..6328
                     /gene="NFATC3"
                     /gene_synonym="n339260; NF-AT4c; NFAT4; NFATX"
                     /note="nuclear factor of activated T cells 3"
                     /db_xref="GeneID:4775"
                     /db_xref="HGNC:HGNC:7777"
                     /db_xref="MIM:602698"
     exon            1..415
                     /gene="NFATC3"
                     /gene_synonym="n339260; NF-AT4c; NFAT4; NFATX"
                     /inference="alignment:Splign:2.1.0"
     CDS             313..3540
                     /gene="NFATC3"
                     /gene_synonym="n339260; NF-AT4c; NFAT4; NFATX"
                     /note="isoform 1 is encoded by transcript variant 1; T
                     cell transcription factor NFAT4; NF-ATc3; nuclear factor
                     of activated T-cells, cytoplasmic, calcineurin-dependent
                     3"
                     /codon_start=1
                     /product="nuclear factor of activated T-cells, cytoplasmic
                     3 isoform 1"
                     /protein_id="NP_775188.1"
                     /db_xref="CCDS:CCDS10860.1"
                     /db_xref="GeneID:4775"
                     /db_xref="HGNC:HGNC:7777"
                     /db_xref="MIM:602698"
                     /translation="MTTANCGAHDELDFKLVFGEDGAPAPPPPGSRPADLEPDDCASI
                     YIFNVDPPPSTLTTPLCLPHHGLPSHSSVLSPSFQLQSHKNYEGTCEIPESKYSPLGG
                     PKPFECPSIQITSISPNCHQELDAHEDDLQINDPEREFLERPSRDHLYLPLEPSYRES
                     SLSPSPASSISSRSWFSDASSCESLSHIYDDVDSELNEAAARFTLGSPLTSPGGSPGG
                     CPGEETWHQQYGLGHSLSPRQSPCHSPRSSVTDENWLSPRPASGPSSRPTSPCGKRRH
                     SSAEVCYAGSLSPHHSPVPSPGHSPRGSVTEDTWLNASVHGGSGLGPAVFPFQYCVET
                     DIPLKTRKTSEDQAAILPGKLELCSDDQGSLSPARETSIDDGLGSQYPLKKDSCGDQF
                     LSVPSPFTWSKPKPGHTPIFRTSSLPPLDWPLPAHFGQCELKIEVQPKTHHRAHYETE
                     GSRGAVKASTGGHPVVKLLGYNEKPINLQMFIGTADDRYLRPHAFYQVHRITGKTVAT
                     ASQEIIIASTKVLEIPLLPENNMSASIDCAGILKLRNSDIELRKGETDIGRKNTRVRL
                     VFRVHIPQPSGKVLSLQIASIPVECSQRSAQELPHIEKYSINSCSVNGGHEMVVTGSN
                     FLPESKIIFLEKGQDGRPQWEVEGKIIREKCQGAHIVLEVPPYHNPAVTAAVQVHFYL
                     CNGKRKKSQSQRFTYTPVLMKQEHREEIDLSSVPSLPVPHPAQTQRPSSDSGCSHDSV
                     LSGQRSLICSIPQTYASMVTSSHLPQLQCRDESVSKEQHMIPSPIVHQPFQVTPTPPV
                     GSSYQPMQTNVVYNGPTCLPINAASSQEFDSVLFQQDATLSGLVNLGCQPLSSIPFHS
                     SNSGSTGHLLAHTPHSVHTLPHLQSMGYHCSNTGQRSLSSPVADQITGQPSSQLQPIT
                     YGPSHSGSATTASPAASHPLASSPLSGPPSPQLQPMPYQSPSSGTASSPSPATRMHSG
                     QHSTQAQSTGQGGLSAPSSLICHSLCDPASFPPDGATVSIKPEPEDREPNFATIGLQD
                     ITLDDVNEIIGRDMSQISVSQGAGVSRQAPLPSPESLDLGRSDGL"
     exon            416..1550
                     /gene="NFATC3"
                     /gene_synonym="n339260; NF-AT4c; NFAT4; NFATX"
                     /inference="alignment:Splign:2.1.0"
     exon            1551..1713
                     /gene="NFATC3"
                     /gene_synonym="n339260; NF-AT4c; NFAT4; NFATX"
                     /inference="alignment:Splign:2.1.0"
     exon            1714..1913
                     /gene="NFATC3"
                     /gene_synonym="n339260; NF-AT4c; NFAT4; NFATX"
                     /inference="alignment:Splign:2.1.0"
     exon            1914..2086
                     /gene="NFATC3"
                     /gene_synonym="n339260; NF-AT4c; NFAT4; NFATX"
                     /inference="alignment:Splign:2.1.0"
     exon            2087..2227
                     /gene="NFATC3"
                     /gene_synonym="n339260; NF-AT4c; NFAT4; NFATX"
                     /inference="alignment:Splign:2.1.0"
     exon            2228..2283
                     /gene="NFATC3"
                     /gene_synonym="n339260; NF-AT4c; NFAT4; NFATX"
                     /inference="alignment:Splign:2.1.0"
     exon            2284..2410
                     /gene="NFATC3"
                     /gene_synonym="n339260; NF-AT4c; NFAT4; NFATX"
                     /inference="alignment:Splign:2.1.0"
     exon            2411..3418
                     /gene="NFATC3"
                     /gene_synonym="n339260; NF-AT4c; NFAT4; NFATX"
                     /inference="alignment:Splign:2.1.0"
     exon            3419..6328
                     /gene="NFATC3"
                     /gene_synonym="n339260; NF-AT4c; NFAT4; NFATX"
                     /inference="alignment:Splign:2.1.0"
     regulatory      6304..6309
                     /regulatory_class="polyA_signal_sequence"
                     /gene="NFATC3"
                     /gene_synonym="n339260; NF-AT4c; NFAT4; NFATX"
                     /note="hexamer: AATAAA"
     polyA_site      6328
                     /gene="NFATC3"
                     /gene_synonym="n339260; NF-AT4c; NFAT4; NFATX"
                     /note="major polyA site"
ORIGIN      
        1 agggcgcgag agcgcacccg cggcggcggt ggcggcgact gtgggggggc ggcggggaac
       61 attggctaag ccgacagtgg aggcttaggc accggtggcg ggcggctgcg gttcctggtg
      121 ctgctcggcg cgcggccagc tttcggaacg gaacgctcgg cgtcgcgggc cccgcccgga
      181 aagtttgccg tggagtcgcg acctcttggc ccgcgcggcc cggcatgaag cggcgttgag
      241 gagctgctgc cgccgcttgc cgctgccgcc gccgccgcct gaggaggagc tgcagcaccc
      301 tgggccacgc cgatgactac tgcaaactgt ggcgcccacg acgagctcga cttcaaactc
      361 gtctttggcg aggacggggc gccggcgccg ccgcccccgg gctcgcggcc tgcagatctt
      421 gagccagatg attgtgcatc catttacatc tttaatgtag atccacctcc atctacttta
      481 accacaccac tttgcttacc acatcatgga ttaccgtctc actcttctgt tttgtcacca
      541 tcgtttcagc tccaaagtca caaaaactat gaaggaactt gtgagattcc tgaatctaaa
      601 tatagcccat taggtggtcc caaacccttt gagtgcccaa gtattcaaat tacatctatc
      661 tctcctaact gtcatcaaga attagatgca catgaagatg acctacagat aaatgaccca
      721 gaacgggaat ttttggaaag gccttctaga gatcatctct atcttcctct tgagccatcc
      781 taccgggagt cttctcttag tcctagtcct gccagcagca tctcttctag gagttggttc
      841 tctgatgcat cttcttgtga atcgctttca catatttatg atgatgtgga ctcagagttg
      901 aatgaagctg cagcccgatt tacccttgga tcccctctga cttctcctgg tggctctcca
      961 gggggctgcc ctggagaaga aacttggcat caacagtatg gacttggaca ctcattatca
     1021 cccaggcaat ctccttgcca ctctcctaga tccagtgtca ctgatgagaa ttggctgagc
     1081 cccaggccag cctcaggacc ctcatcaagg cccacatccc cctgtgggaa acggaggcac
     1141 tccagtgctg aagtttgtta tgctgggtcc ctttcacccc atcactcacc tgttccttca
     1201 cctggtcact cccccagggg aagtgtgaca gaagatacgt ggctcaatgc ttctgtccat
     1261 ggtgggtcag gccttggccc tgcagttttt ccatttcagt actgtgtaga gactgacatc
     1321 cctctcaaaa caaggaaaac ttctgaagat caagctgcca tactaccagg aaaattagag
     1381 ctgtgttcag atgaccaagg gagtttatca ccagcccggg agacttcaat agatgatggc
     1441 cttggatctc agtatccttt aaagaaagat tcatgtggtg atcagtttct ttcagttcct
     1501 tcacccttta cctggagcaa accaaagcct ggccacaccc ctatatttcg cacatcttca
     1561 ttacctccac tagactggcc tttaccagct cattttggac aatgtgaact gaaaatagaa
     1621 gtgcaaccta aaactcatca tcgagcccat tatgaaactg aaggtagccg aggggcagta
     1681 aaagcatcta ctgggggaca tcctgttgtg aagctcctgg gctataacga aaagccaata
     1741 aatctacaaa tgtttattgg gacagcagat gatcgatatt tacgacctca tgcattttac
     1801 caggtgcatc gaatcactgg gaagacagtc gctactgcaa gccaagagat aataattgcc
     1861 agtacaaaag ttctggaaat tccacttctt cctgaaaata atatgtcagc cagtattgat
     1921 tgtgcaggta ttttgaaact ccgcaattca gatatagaac ttcgaaaagg agaaactgat
     1981 attggcagaa agaatactag agtacgactt gtgtttcgtg tacacatccc acagcccagt
     2041 ggaaaagtcc tttctctgca gatagcctct atacccgttg agtgctccca gcggtctgct
     2101 caagaacttc ctcatattga gaagtacagt atcaacagtt gttctgtaaa tggaggtcat
     2161 gaaatggttg tgactggatc taattttctt ccagaatcca aaatcatttt tcttgaaaaa
     2221 ggacaagatg gacgacctca gtgggaggta gaagggaaga taatcaggga aaaatgtcaa
     2281 ggggctcaca ttgtccttga agttcctcca tatcataacc cagcagttac agctgcagtg
     2341 caggtgcact tttatctttg caatggcaag aggaaaaaaa gccagtctca acgttttact
     2401 tatacaccag ttttgatgaa gcaagaacac agagaagaga ttgatttgtc ttcagttcca
     2461 tctttgcctg tgcctcatcc tgctcagacc cagaggcctt cctctgattc agggtgttca
     2521 catgacagtg tactgtcagg acagagaagt ttgatttgct ccatcccaca aacatatgca
     2581 tccatggtga cctcatccca tctgccacag ttgcagtgta gagatgagag tgttagtaaa
     2641 gaacagcata tgattccttc tccaattgta caccagcctt ttcaagtcac accaacacct
     2701 cctgtggggt cttcctatca gcctatgcaa actaatgttg tgtacaatgg accaacttgt
     2761 cttcctatta atgctgcctc tagtcaagaa tttgattcag ttttgtttca gcaggatgca
     2821 actctttctg gtttagtgaa tcttggctgt caaccactgt catccatacc atttcattct
     2881 tcaaattcag gctcaacagg acatctctta gcccatacac ctcattctgt gcataccctg
     2941 cctcatctgc aatcaatggg atatcattgt tcaaatacag gacaaagatc tctttcttct
     3001 ccagtggctg accagattac aggtcagcct tcgtctcagt tacaacctat tacatatggt
     3061 ccttcacatt cagggtctgc tacaacagct tccccagcag cttctcatcc cttggctagt
     3121 tcaccgcttt ctgggccacc atctcctcag cttcagccta tgccttacca atctcctagc
     3181 tcaggaactg cctcatcacc gtctccagcc accagaatgc attctggaca gcactcaact
     3241 caagcacaaa gtacgggcca ggggggtctt tctgcacctt catccttaat atgtcacagt
     3301 ttgtgtgatc cagcgtcatt tccacctgat ggggcaactg tgagcattaa acctgaacca
     3361 gaagatcgag agcctaactt tgcaaccatt ggtctgcagg acatcacttt agatgatgtg
     3421 aacgagataa ttgggagaga catgtcccag atttctgttt cccaaggagc aggggtgagc
     3481 aggcaggctc ccctcccgag tcctgagtcc ctggatttag gaagatctga tgggctctaa
     3541 cagtgcttac tgcagccttg tgtccaccac caacttctca gcatgtttct ctccttggac
     3601 cttgggtttc caactctgca gccttcaggt ctggggccag gagtgggacc caccatttgt
     3661 ggggaaagta gcattcctcc acctcaggcc ttgggtagat ttggcaaaag aacaggagca
     3721 gcataggctg tttgagcttt ggggaaatga actttgcttt ttatatttaa ctaggatact
     3781 tttatatgat gggtgctttg agtgtgaatg cagcaggctc tcttgtttcc gaggtgctgc
     3841 ttttgcaggt gacctggtta cttagctagg attggtgatt tgtactgctt tatggtcatt
     3901 tgaagggccc tttagttttt atgataattt ttaaaatagg aacttttgat aagaccttct
     3961 agaagcaaaa aaaaaaaaaa aaaaaaaaaa aagaaaaaaa aagaaaagaa aaaaagaaaa
     4021 agaaaaaaat atcccaagcc cacacctatg cctcagaaag tcagcatgtg tcctgaagac
     4081 gttcatagat ttataggaaa taaagccaaa tgtagctcat acctctttat aaaactaaac
     4141 tgttgttaga taaaatgaga agagaccatt ccatcattga agtgttggaa tataaaaaga
     4201 cattccagag catagccttt tggtaacttt ctaggtaatc ttgcaatctc tccatactgg
     4261 ctccatgttg aaattgcttt ttccctcagg accctgggta agatggctac atttaaggtg
     4321 actctgaatg gtggggttct agcttggtca ctttcatttc ttgccatcat aaaaactagt
     4381 aggctgtgga gtgcgcttcc tgtttgtgtc atctggtcgt agaacctttt ccaaacagaa
     4441 gcatctgcct ttggctgttc tgtgaccttt gaagccagtc tcagtggttt aggcagcttt
     4501 gcagttctaa ctctagctag aggccaggct gtgtgcagag ctaaagcaca aatgagcagt
     4561 acatcagcat gggcagagaa aatacaggac tccagatggg aaggttttaa gagtcacact
     4621 ggcatggaag gcttatctgc cattctattt atagcctgaa atgattctgg cctaccctgt
     4681 cctgtctgta tgatctaaaa accagccttt tccccagaag gctctgagca catccagaag
     4741 tgataacctg accctccaca ccaaagacac cctggtgctg ctgctggtga gactggtgtc
     4801 caaggcaggg cccagcagaa actgcagcct gctgtctacc aaaggaggta cccgagttgg
     4861 gtactttaaa aaaaaaaaaa acctgccctt acccctctcc ctaatgggat tttttttacc
     4921 tgttcctggg cccattacag agcctctgaa gtttgcagta tgctttcaaa tgaaataata
     4981 tacttccatt gattcaggaa gcagattttt tgagtgccta tatgtgagac agtgtgctgg
     5041 ttgaaggcct gatgctgtta ttccaggaga ctgcaggccc ttgatgccag gactctctct
     5101 actaaggcca gttcaggtct gggaaaggga gctggcctat tgcccaccac ctgttgtcag
     5161 taggttagga gctgttgact caggatgagg aagtatggtc tttaaaaaaa acaaaatata
     5221 ttttagattt ctcccctaaa gttagttaga gaaaaaggtc tattcttcag cagatcactg
     5281 tggcccctct tggagctggg tgttttcaaa ttttcttgaa aagtgagttg tgtcacagaa
     5341 tgtggatagt gagatttgct tctgggcctg tggttggacg cccacagctt cctttggagg
     5401 ggcaagaagt tggcctctcg gttgacattc cagagaaatg gccagacttg cccctaccct
     5461 tttgcccctg gtgtagctgc ctcacatgag gttattgcaa gagttcccct tgcaataccc
     5521 tttgtgccct caagaattaa aagcctctat gatccagagt tgctatgcac caaattttga
     5581 tgccttctaa ataccttgat gcctgtagca ctagaaatgc tttcctattt aaaataaaca
     5641 ttaaatttta aaatagagct ttgtatacta tgtaagcagt tttatatcag ctttgtaaaa
     5701 gctttggtgt taagagtcaa tattttttgg ctttgtagat aaagacttaa atttttgtgc
     5761 aacatagtgg tgttaaagca cacatccatt ggactatgca aatcaatttc tactagcagc
     5821 actgagcaac tgggcacgtg ctagtacgca ccccctccta ctctaactgt gctagctctt
     5881 gggttgagga atggaatggg tagccttctg cttactggag atgcacagag aaacatggct
     5941 gaaaacagct ttaaaaagaa catgtctttg ggttcatgtg tggtgctgct gcccgggtgt
     6001 aaactatccc cacccagggc cagccattat caccagacct cttctgggcc tggctgtgaa
     6061 gccctgtttt tggtattcag aatggatctt taaggctcag atgggctcaa attgaaacct
     6121 tgtgttttat aaaatggatg tttagtaaag gaactggttc tcagttatgt ttacagcact
     6181 tggaattgtg tgttcttgta cattttgtat tttaaaacct tttatgggag tgcagtgctc
     6241 cttacacaaa tacaaaggga agaagagcca gcagttgagg ctcctcagtt ttagtgctga
     6301 aataataaac agtgacaggt caacagta
//
