LOCUS       NM_000268               5950 bp    mRNA    linear   PRI 12-OCT-2024
DEFINITION  Homo sapiens NF2, moesin-ezrin-radixin like (MERLIN) tumor
            suppressor (NF2), transcript variant 1, mRNA.
ACCESSION   NM_000268
VERSION     NM_000268.4
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 5950)
  AUTHORS   Bian,Z., Xu,C., Wang,X., Zhang,B., Xiao,Y., Liu,L., Zhao,S.,
            Huang,N., Yang,F., Zhang,Y., Xue,S., Wang,X., Pan,Q. and Sun,F.
  TITLE     TRIM65/NF2/YAP1 Signaling Coordinately Orchestrates Metabolic and
            Immune Advantages in Hepatocellular Carcinoma
  JOURNAL   Adv Sci (Weinh) 11 (35), e2402578 (2024)
   PUBMED   39005234
  REMARK    GeneRIF: TRIM65/NF2/YAP1 Signaling Coordinately Orchestrates
            Metabolic and Immune Advantages in Hepatocellular Carcinoma.
REFERENCE   2  (bases 1 to 5950)
  AUTHORS   Vlashi,R., Sun,F., Zheng,C., Zhang,X., Liu,J. and Chen,G.
  TITLE     The molecular biology of NF2/Merlin on tumorigenesis and
            development
  JOURNAL   FASEB J 38 (13), e23809 (2024)
   PUBMED   38967126
  REMARK    GeneRIF: The molecular biology of NF2/Merlin on tumorigenesis and
            development.
            Review article
REFERENCE   3  (bases 1 to 5950)
  AUTHORS   Lei,Z., Niu,J., Cai,H., Kong,Z., Ding,X., Dong,Y., Zhang,D., Li,X.,
            Shao,J., Lin,A., Zhou,R., Yang,S. and Yan,Q.
  TITLE     NF2 regulates IP3R-mediated Ca2+ signal and apoptosis in
            meningiomas
  JOURNAL   FASEB J 38 (13), e23737 (2024)
   PUBMED   38953724
  REMARK    GeneRIF: NF2 regulates IP3R-mediated Ca[2+] signal and apoptosis in
            meningiomas.
REFERENCE   4  (bases 1 to 5950)
  AUTHORS   Chen,Y., Steiner,S., Hagedorn,C., Kollar,S., Pliego-Mendieta,A.,
            Haberecker,M., Plock,J., Britschgi,C., Planas-Paz,L. and Pauli,C.
  TITLE     Acquired NF2 mutation confers resistance to TRK inhibition in an ex
            vivo LMNA::NTRK1-rearranged soft-tissue sarcoma cell model
  JOURNAL   J Pathol 263 (2), 257-269 (2024)
   PUBMED   38613194
  REMARK    GeneRIF: Acquired NF2 mutation confers resistance to TRK inhibition
            in an ex vivo LMNA::NTRK1-rearranged soft-tissue sarcoma cell
            model.
REFERENCE   5  (bases 1 to 5950)
  AUTHORS   Ma,W., Zhang,J., Chen,W., Liu,N. and Wu,T.
  TITLE     The histone lysine acetyltransferase KAT2B inhibits
            cholangiocarcinoma growth: evidence for interaction with SP1 to
            regulate NF2-YAP signaling
  JOURNAL   J Exp Clin Cancer Res 43 (1), 117 (2024)
   PUBMED   38641672
  REMARK    GeneRIF: The histone lysine acetyltransferase KAT2B inhibits
            cholangiocarcinoma growth: evidence for interaction with SP1 to
            regulate NF2-YAP signaling.
            Publication Status: Online-Only
REFERENCE   6  (bases 1 to 5950)
  AUTHORS   den Bakker,M.A., Tascilar,M., Riegman,P.H., Hekman,A.C.,
            Boersma,W., Janssen,P.J., de Jong,T.A., Hendriks,W., van der
            Kwast,T.H. and Zwarthoff,E.C.
  TITLE     Neurofibromatosis type 2 protein co-localizes with elements of the
            cytoskeleton
  JOURNAL   Am J Pathol 147 (5), 1339-1349 (1995)
   PUBMED   7485397
REFERENCE   7  (bases 1 to 5950)
  AUTHORS   Evans,D.G., Bourn,D., Wallace,A., Ramsden,R.T., Mitchell,J.D. and
            Strachan,T.
  TITLE     Diagnostic issues in a family with late onset type 2
            neurofibromatosis
  JOURNAL   J Med Genet 32 (6), 470-474 (1995)
   PUBMED   7666400
REFERENCE   8  (bases 1 to 5950)
  AUTHORS   Honda,M., Arai,E., Sawada,S., Ohta,A. and Niimura,M.
  TITLE     Neurofibromatosis 2 and neurilemmomatosis gene are identical
  JOURNAL   J Invest Dermatol 104 (1), 74-77 (1995)
   PUBMED   7798645
REFERENCE   9  (bases 1 to 5950)
  AUTHORS   Evans,D.G.
  TITLE     NF2-Related Schwannomatosis
  JOURNAL   (in) Adam MP, Feldman J, Mirzaa GM, Pagon RA, Wallace SE and
            Amemiya A (Eds.);
            GENEREVIEWS(R);
            (1993)
   PUBMED   20301380
REFERENCE   10 (bases 1 to 5950)
  AUTHORS   Arai,E., Ikeuchi,T., Karasawa,S., Tamura,A., Yamamoto,K., Kida,M.,
            Ichimura,K., Yuasa,Y. and Tonomura,A.
  TITLE     Constitutional translocation t(4;22) (q12;q12.2) associated with
            neurofibromatosis type 2
  JOURNAL   Am J Med Genet 44 (2), 163-167 (1992)
   PUBMED   1456285
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from AF369657.1 and AC004882.3.
            
            On Nov 13, 2019 this sequence version replaced NM_000268.3.
            
            Summary: This gene encodes a protein that is similar to some
            members of the ERM (ezrin, radixin, moesin) family of proteins that
            link cytoskeletal components with proteins in the cell membrane.
            The encoded protein is involved in regulation of contact-dependent
            inhibition of cell proliferation and functions in cell-cell
            adhesion and transmembrane signaling. The encoded protein has been
            shown to interact with cell-surface proteins, proteins involved in
            cytoskeletal dynamics, and proteins involved in regulating ion
            transport. Disruption of this protein's function has been
            implicated in tumorigenesis and metastasis. Mutations in this gene
            are associated with neurofibromatosis type II which is
            characterized by nervous system and skin tumors and ocular
            abnormalities. [provided by RefSeq, May 2022].
            
            Transcript Variant: This variant (1) encodes the longest isoform
            (1).
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AF369657.1, SRR18074967.1749160.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1965299, SAMEA1966682
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000338641.10/ ENSP00000344666.5
            RefSeq Select criteria :: based on manual assertion, conservation,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-2106              AF369657.1         60-2165
            2107-5950           AC004882.3         41361-45204
FEATURES             Location/Qualifiers
     source          1..5950
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="22"
                     /map="22q12.2"
     gene            1..5950
                     /gene="NF2"
                     /gene_synonym="ACN; BANF; merlin-1; SCH; SWNV"
                     /note="NF2, moesin-ezrin-radixin like (MERLIN) tumor
                     suppressor"
                     /db_xref="GeneID:4771"
                     /db_xref="HGNC:HGNC:7773"
                     /db_xref="MIM:607379"
     exon            1..480
                     /gene="NF2"
                     /gene_synonym="ACN; BANF; merlin-1; SCH; SWNV"
                     /inference="alignment:Splign:2.1.0"
     CDS             367..2154
                     /gene="NF2"
                     /gene_synonym="ACN; BANF; merlin-1; SCH; SWNV"
                     /note="isoform 1 is encoded by transcript variant 1;
                     moesin-ezrin-radixin like; neurofibromin 2 (bilateral
                     acoustic neuroma); schwannomin; moesin-ezrin-radizin-like
                     protein; schwannomerlin; merlin; moesin-ezrin-radixin-like
                     protein; neurofibromin-2; bilateral acoustic
                     neurofibromatosis"
                     /codon_start=1
                     /product="merlin isoform 1"
                     /protein_id="NP_000259.1"
                     /db_xref="CCDS:CCDS13861.1"
                     /db_xref="GeneID:4771"
                     /db_xref="HGNC:HGNC:7773"
                     /db_xref="MIM:607379"
                     /translation="MAGAIASRMSFSSLKRKQPKTFTVRIVTMDAEMEFNCEMKWKGK
                     DLFDLVCRTLGLRETWFFGLQYTIKDTVAWLKMDKKVLDHDVSKEEPVTFHFLAKFYP
                     ENAEEELVQEITQHLFFLQVKKQILDEKIYCPPEASVLLASYAVQAKYGDYDPSVHKR
                     GFLAQEELLPKRVINLYQMTPEMWEERITAWYAEHRGRARDEAEMEYLKIAQDLEMYG
                     VNYFAIRNKKGTELLLGVDALGLHIYDPENRLTPKISFPWNEIRNISYSDKEFTIKPL
                     DKKIDVFKFNSSKLRVNKLILQLCIGNHDLFMRRRKADSLEVQQMKAQAREEKARKQM
                     ERQRLAREKQMREEAERTRDELERRLLQMKEEATMANEALMRSEETADLLAEKAQITE
                     EEAKLLAQKAAEAEQEMQRIKATAIRTEEEKRLMEQKVLEAEVLALKMAEESERRAKE
                     ADQLKQDLQEAREAERRAKQKLLEIATKPTYPPMNPIPAPLPPDIPSFNLIGDSLSFD
                     FKDTDMKRLSMEIEKEKVEYMEKSKHLQEQLNELKTEIEALKLKERETALDILHNENS
                     DRGGSSKHNTIKKLTLQSAKSRVAFFEEL"
     exon            481..606
                     /gene="NF2"
                     /gene_synonym="ACN; BANF; merlin-1; SCH; SWNV"
                     /inference="alignment:Splign:2.1.0"
     exon            607..729
                     /gene="NF2"
                     /gene_synonym="ACN; BANF; merlin-1; SCH; SWNV"
                     /inference="alignment:Splign:2.1.0"
     exon            730..813
                     /gene="NF2"
                     /gene_synonym="ACN; BANF; merlin-1; SCH; SWNV"
                     /inference="alignment:Splign:2.1.0"
     exon            814..882
                     /gene="NF2"
                     /gene_synonym="ACN; BANF; merlin-1; SCH; SWNV"
                     /inference="alignment:Splign:2.1.0"
     exon            883..965
                     /gene="NF2"
                     /gene_synonym="ACN; BANF; merlin-1; SCH; SWNV"
                     /inference="alignment:Splign:2.1.0"
     exon            966..1041
                     /gene="NF2"
                     /gene_synonym="ACN; BANF; merlin-1; SCH; SWNV"
                     /inference="alignment:Splign:2.1.0"
     exon            1042..1176
                     /gene="NF2"
                     /gene_synonym="ACN; BANF; merlin-1; SCH; SWNV"
                     /inference="alignment:Splign:2.1.0"
     exon            1177..1251
                     /gene="NF2"
                     /gene_synonym="ACN; BANF; merlin-1; SCH; SWNV"
                     /inference="alignment:Splign:2.1.0"
     exon            1252..1365
                     /gene="NF2"
                     /gene_synonym="ACN; BANF; merlin-1; SCH; SWNV"
                     /inference="alignment:Splign:2.1.0"
     exon            1366..1488
                     /gene="NF2"
                     /gene_synonym="ACN; BANF; merlin-1; SCH; SWNV"
                     /inference="alignment:Splign:2.1.0"
     exon            1489..1706
                     /gene="NF2"
                     /gene_synonym="ACN; BANF; merlin-1; SCH; SWNV"
                     /inference="alignment:Splign:2.1.0"
     exon            1707..1812
                     /gene="NF2"
                     /gene_synonym="ACN; BANF; merlin-1; SCH; SWNV"
                     /inference="alignment:Splign:2.1.0"
     exon            1813..1940
                     /gene="NF2"
                     /gene_synonym="ACN; BANF; merlin-1; SCH; SWNV"
                     /inference="alignment:Splign:2.1.0"
     exon            1941..2103
                     /gene="NF2"
                     /gene_synonym="ACN; BANF; merlin-1; SCH; SWNV"
                     /inference="alignment:Splign:2.1.0"
     exon            2104..5950
                     /gene="NF2"
                     /gene_synonym="ACN; BANF; merlin-1; SCH; SWNV"
                     /inference="alignment:Splign:2.1.0"
     regulatory      5928..5933
                     /regulatory_class="polyA_signal_sequence"
                     /gene="NF2"
                     /gene_synonym="ACN; BANF; merlin-1; SCH; SWNV"
                     /note="hexamer: AATAAA"
     polyA_site      5950
                     /gene="NF2"
                     /gene_synonym="ACN; BANF; merlin-1; SCH; SWNV"
                     /note="major polyA site"
ORIGIN      
        1 gtgaccctag tcggccgctg agaggcgcgc ggagtctggg ccgctgccgt ctaggggtcc
       61 cgtcccgagg cgtccccggc atctccggcc cgaatcccgg agtgccgggt cgcgcctgca
      121 ccgaaggtcc cggctcctgt gccctccctg cagccgtcag ggcccgtccc ccaactcccc
      181 tttccgctca ggcagggtcc tcgcggccca tgctggccgc tggggacccg cgcagcccag
      241 accgttcccg ggccgggcag ccggccacca tggtggccct gaggcctgtg cagcaactcc
      301 aggggggcta aagggctcag agtgcaggcc gtggggcgcg agggtcccgg gcctgagccc
      361 cgcgccatgg ccggggccat cgcttcccgc atgagcttca gctctctcaa gaggaagcaa
      421 cccaagacgt tcaccgtgag gatcgtcacc atggacgccg agatggagtt caattgcgag
      481 atgaagtgga aagggaagga cctctttgat ttggtgtgcc ggactctggg gctccgagaa
      541 acctggttct ttggactgca gtacacaatc aaggacacag tggcctggct caaaatggac
      601 aagaaggtac tggatcatga tgtttcaaag gaagaaccag tcacctttca cttcttggcc
      661 aaattttatc ctgagaatgc tgaagaggag ctggttcagg agatcacaca acatttattc
      721 ttcttacagg taaagaagca gattttagat gaaaagatct actgccctcc tgaggcttct
      781 gtgctcctgg cttcttacgc cgtccaggcc aagtatggtg actacgaccc cagtgttcac
      841 aagcggggat ttttggccca agaggaattg cttccaaaaa gggtaataaa tctgtatcag
      901 atgactccgg aaatgtggga ggagagaatt actgcttggt acgcagagca ccgaggccga
      961 gccagggatg aagctgaaat ggaatatctg aagatagctc aggacctgga gatgtacggt
     1021 gtgaactact ttgcaatccg gaataaaaag ggcacagagc tgctgcttgg agtggatgcc
     1081 ctggggcttc acatttatga ccctgagaac agactgaccc ccaagatctc cttcccgtgg
     1141 aatgaaatcc gaaacatctc gtacagtgac aaggagttta ctattaaacc actggataag
     1201 aaaattgatg tcttcaagtt taactcctca aagcttcgtg ttaataagct gattctccag
     1261 ctatgtatcg ggaaccatga tctatttatg aggagaagga aagccgattc tttggaagtt
     1321 cagcagatga aagcccaggc cagggaggag aaggctagaa agcagatgga gcggcagcgc
     1381 ctcgctcgag agaagcagat gagggaggag gctgaacgca cgagggatga gttggagagg
     1441 aggctgctgc agatgaaaga agaagcaaca atggccaacg aagcactgat gcggtctgag
     1501 gagacagctg acctgttggc tgaaaaggcc cagatcaccg aggaggaggc aaaacttctg
     1561 gcccagaagg ccgcagaggc tgagcaggaa atgcagcgca tcaaggccac agcgattcgc
     1621 acggaggagg agaagcgcct gatggagcag aaggtgctgg aagccgaggt gctggcactg
     1681 aagatggctg aggagtcaga gaggagggcc aaagaggcag atcagctgaa gcaggacctg
     1741 caggaagcac gcgaggcgga gcgaagagcc aagcagaagc tcctggagat tgccaccaag
     1801 cccacgtacc cgcccatgaa cccaattcca gcaccgttgc ctcctgacat accaagcttc
     1861 aacctcattg gtgacagcct gtctttcgac ttcaaagata ctgacatgaa gcggctttcc
     1921 atggagatag agaaagaaaa agtggaatac atggaaaaga gcaagcatct gcaggagcag
     1981 ctcaatgaac tcaagacaga aatcgaggcc ttgaaactga aagagaggga gacagctctg
     2041 gatattctgc acaatgagaa ctccgacagg ggtggcagca gcaagcacaa taccattaaa
     2101 aagctcacct tgcagagcgc caagtcccga gtggccttct ttgaagagct ctagcaggtg
     2161 acccagccac cccaggacct gccacttctc ctgctaccgg gaccgcggga tggaccagat
     2221 atcaagagag ccatccatag ggagctggct gggggtttcc gtgggagctc cagaactttc
     2281 cccagctgag tgaagagccc agcccctctt atgtgcaatt gccttgaact acgaccctgt
     2341 agagatttct ctcatggcgt tctagttctc tgacctgagt ctttgtttta agaagtattt
     2401 gtcttccttt gtctaatgtg ggattcctga ctcccttcgt ccaaggcacc ggtgtgtgtg
     2461 tgtcttgcac tccagagctg acctccaccg cccagcctgg gaagtcattg tagggagtga
     2521 gacactgaag ccctgagaag ccagtgccat catccccacc ccgcccaggg ttccggaaca
     2581 ttcattcccc caccggtgag gacctggcat gcagcgaagc agcccagccc ggcggatccc
     2641 aggccagcac gcctgccggc ttctcatcgt cagggagccc gcccagagct cgtgacgagc
     2701 aagtgctggg tccccgccag gcaccccgag gcggcgctct ggctggcagc tggtggggaa
     2761 taggcagggc agctgtggct ggggagagac tttaggcaga agctgtgatg caggctgact
     2821 gccagccgag gggctgggta gtgccgtgcg ggagctgatg gtacagggca ctcgctgtcc
     2881 ccctccggcc accctagacc agggtccgag aggcaggcag gagccactca tgtcttcccc
     2941 attgcccgac gcccatagac gctccttcct gtgtggggct ggggtactcc ctggtcgtac
     3001 tgcagtcagc acccgtaacc cggctatgac cagggatctg taagccctgt ggctccacag
     3061 gtgctgcttc tcactggccc agactctgag ctccaccggc ccagtctgca cggcccatct
     3121 gcttcacctt ccctcccagc cacgtgccag tggccacagc ccacttccca acccactgtt
     3181 gtacccaggc ctcactttgc tgttgccctt gtccctcttc gggccctgaa ttttctgttc
     3241 cctgggggcc agccagggcc ctttgtgccc ctcccagcac aggcctgatg caggtgtcca
     3301 ctcacaggtg gcgctcacct aggctgtcac aggacccacc tccatgccag gcaacagagg
     3361 gccacagaac cacccccacg gctcactcct tggtctgggg ccaccttctt gccctttctt
     3421 tttttttttt tttttttttt tccgagatgg agtctctctc tgtcacccag gtgggagtgt
     3481 ggtggcacaa tctcggctca ctgcaacctc cacctcctga gttcaagcaa ttctcctgcc
     3541 tcagcctccc aagtagctgg gactacaggc atgcaccacc acacttggcc aatgttctgt
     3601 atttttaata gggacggggt tttgccatgt tagctaggct ggtctcaaac tcacacctgg
     3661 gattacaggc atgagccact gcacccagcc ccttcttgcc ctttcttttc tccatggctg
     3721 atgctgctgt ggccagccag ggcccttgag atccttccag tttggctgtt atgcaaagca
     3781 ggtgatttgt cttaatcaga taaaagatag aggctatggg ggcctcaaga tttttggaga
     3841 gcagaggtgg tctctggcaa ttccatctgg ttttgagaaa cttagcagct cacagagcac
     3901 agagatcctg ccttcttcct actatcaggc tgacctaatg gggttgggct gctcggcaac
     3961 tgcttgggtc accttgcccc aaggaaacca gccctgggtg ccacccagcc acttagggtc
     4021 tacagggtgg gactccagac ctagagcgta agtatggatg ttgtggccct gtgtcttcct
     4081 agtgtgaccc agccaggagc ggaagcttca ggcgtttgta aagtgaggtc tggctctgcc
     4141 tcctccgttt tttttttttt tctgtttctg tttctgtttt ttttttgaga tggagtctcg
     4201 ctctgtcgcc caggctggag tgcagtgtca cgatctcagc tcactgcaac ctccgcctcc
     4261 caggtacaag agattctcct gcctcagcct cccgagtagc tgggactaca ggcgtgtgcc
     4321 accatgcctg gctaattttt gtatttttag tagagatggg gtttcgccat gttagccaga
     4381 ctggtctcga actcctgacc tcaggtgatc ctcccacccc ggcttcccaa agttctggga
     4441 ttataggcgt gagccaccat gcccggtctc ttctcagtct tgaagcccat ccctggattt
     4501 ccaccaggag ttactttcct cctgacctgt aaatttgttc tttaacaatg gctgcaggtg
     4561 ggagcatatg gtggtttata aaaacgctgt cgggctttgt ttccttcttt agctgccgtg
     4621 tctacttctg aagtctggga agtgccaagc cacgcggcct caagggagct ggctggtgtt
     4681 tgagctgtgg cagaagcacc tggggctcca gggagcaggc tgggaactgc aggaccttgc
     4741 tcagccagga gcacttcccc ctccttgagg caggaatact gaggtgcctc cccacagatg
     4801 gagaaggtgg agaggaggat gggcctcagg agcatctcaa gccccagtag caggagaaag
     4861 aaagaaagag atgcctggtt ttcacagact ggttcctgtg gctgggatga ctgcatcctt
     4921 tttttttttt ttttgagacg gagtttttgc ctttgtcgcc caggctggag tgcaatggcg
     4981 tgatctcggc tcaccgcaac ctccgcctcc cggattcaag caattctcct gcctcagcct
     5041 cccgagtagc tgggattaca ggcacgcacc tccacgtccg gctaattttg tatttttagt
     5101 ggagacgggg tttctccatg tcggtcaggc tggtctcgaa ctcccgacct caggtgatct
     5161 gcccacctcg gcctcccaaa gtgctgggat tacaggcatg agccaccgcg cttggccaga
     5221 ctgcgtcctt tttaagcgaa cattttaggg cctgggagtt tgtcaagtaa ggaagtctca
     5281 agcccaaaga gcagcgtcct gaccatggtg gtttcattac gagcccttct gctggctctc
     5341 aggcagaagc cccacagcac cgggaccatt catgaggtca ctgcccagct catgatgtcc
     5401 gtgaggctgt ccttttggcc agtagccgtg tgcagctgtg tggcacagat ggcttcgttc
     5461 atcctgatca aggccccacc tcagccacag cagtcccccc aacctgtgtt gtccacccta
     5521 ttattcatgt acctgccagg ccctgctaga tagcaccccg tggcattaca taacacttca
     5581 tgagtggctg tgtcttgtaa ttttggggac aggtttctct ctttccctct cttttttttg
     5641 tcaaaagccc agagactgac aaccagctgc agtgtctaag tgttcctcac tgacagggtg
     5701 gggcctcacc acccctggag ggagcagcgt tggcagggag acagcctggc ccagtgaccc
     5761 tgggcccaag ccagcccctc cagggctttc agggaagcgc catccatttt caaagatgtc
     5821 aaacgtcact tcttcctgta gggcccgagt cctgcctcct atcagggcca gatcatagaa
     5881 ggctattttc tattctgggg aacgattata acttaaatga ttgttttaat aaaaattcta
     5941 agctggaaaa
//
