LOCUS       XM_047448774            2737 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens NIMA related kinase 4 (NEK4), transcript
            variant X6, mRNA.
ACCESSION   XM_047448774
VERSION     XM_047448774.1
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000003.12) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2737
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="3"
     gene            1..2737
                     /gene="NEK4"
                     /gene_synonym="NRK2; pp12301; STK2"
                     /note="NIMA related kinase 4; Derived by automated
                     computational analysis using gene prediction method:
                     Gnomon. Supporting evidence includes similarity to: 1
                     mRNA, 141 ESTs, 136 long SRA reads, 1 Protein, and 94%
                     coverage of the annotated genomic feature by RNAseq
                     alignments, including 13 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:6787"
                     /db_xref="HGNC:HGNC:11399"
                     /db_xref="MIM:601959"
     CDS             195..2072
                     /gene="NEK4"
                     /gene_synonym="NRK2; pp12301; STK2"
                     /codon_start=1
                     /product="serine/threonine-protein kinase Nek4 isoform X6"
                     /protein_id="XP_047304730.1"
                     /db_xref="GeneID:6787"
                     /db_xref="HGNC:HGNC:11399"
                     /db_xref="MIM:601959"
                     /translation="MPLAAYCYLRVVGKGSYGEVTLVKHRRDGKQYVIKKLNLRNASS
                     RERRAAEQEAQLLSQLKHPNIVTYKESWEGGDGLLYIVMGFCEGGDLYRKLKEQKGQL
                     LPENQVVEWFVQIAMALQYLHEKHILHRDLKTQNVFLTRTNIIKVGDLGIARVLENHC
                     DMASTLIGTPYYMSPELFSNKPYNYKSDVWALGCCVYEMATLKHAFNAKDMNSLVYRI
                     IEGKLPPMPRDYSPELAELIRTMLSKRPEERPSVRSILRQPYIKRQISFFLEATKIKT
                     SKNNIKNGDSQSKPFATVVSGEAESNHEVIHPQPLSSEGSQTYIMGEGKCLSQEKPRA
                     SGLLKSPASLKAHTCKQDLSNTTELATISSVNIDILPAKGRDSVSDGFVQENQPRYLD
                     ASNELGGICSISQVEEEMLQDNTKSSAQPENLIPMWSSDIVTGEKNEPVKPLQPLIKE
                     QKPKDQDQVAGECIIEKQGRIHPDLQPHNSGSEPSLSRQRRQKRREQTEHRGEKRQVR
                     RDLFAFQESPPRFLPSHPIVGKVDVTSTQKEAENQRRVVTGSVSSSRSSEMSSSKDRP
                     LSARERRRLKQSQEEMSSSGPSVRKASLSVAGPGKPQEEDQPLPARRLSSDCSVTQVI
                     L"
     polyA_site      2737
                     /gene="NEK4"
                     /gene_synonym="NRK2; pp12301; STK2"
                     /experiment="COORDINATES: polyA evidence [ECO:0006239]"
ORIGIN      
        1 agaactgctc ccggcccgga tcgctatggc agcggcgtcg tcgcgggccg ggccccagca
       61 atcccgcccg ggcccggctg cctcaacagc cgcccccact gccccctctc gggcatgaac
      121 cgagcttctt gttgccgccc gctgccctac ccgccgctgc cgccgcatcc cgactctggg
      181 ccagcgctgg gaacatgccc ctggccgcct actgctacct gcgggtcgtg ggcaagggga
      241 gctatggaga ggtgacgctt gtgaagcacc ggcgggacgg caagcagtat gtcatcaaaa
      301 aactgaacct ccgaaatgcc tctagccgag agcggcgagc tgctgaacag gaagcccagc
      361 tcttgtctca gttgaagcat cccaacattg tcacctacaa ggagtcatgg gaaggaggag
      421 atggtctgct ctacattgtc atgggcttct gtgaaggagg tgatttgtac cgaaagctca
      481 aggagcagaa agggcagctt ctgcctgaga atcaggtggt agagtggttt gtacagatcg
      541 ccatggcttt gcagtattta catgaaaaac acatccttca tcgagatctg aaaactcaaa
      601 atgtcttcct aacaagaaca aacatcatca aagtagggga cctaggaatt gcccgagtgt
      661 tagagaacca ctgtgacatg gctagcaccc tcattggcac accctactac atgagccctg
      721 aattgttctc aaacaaaccc tacaactata agtctgatgt ttgggctcta ggatgctgtg
      781 tctatgaaat ggccaccttg aagcatgctt tcaatgcaaa agatatgaat tctttagttt
      841 atcggattat tgaaggaaag ctgccaccaa tgccaagaga ttacagccca gagctggcag
      901 aactgataag aacaatgctg agcaaaaggc ctgaagaaag gccgtctgtg aggagcatcc
      961 tgaggcagcc ttatataaag cggcaaatct ccttcttttt ggaggccaca aagataaaaa
     1021 cctccaaaaa taacattaaa aatggtgact ctcaatccaa gccttttgct acagtggttt
     1081 ctggagaggc agaatcaaat catgaagtaa tccaccccca accactctct tctgagggct
     1141 cccagacata tataatgggt gaaggcaaat gtttgtccca ggagaaaccc agggcctctg
     1201 gtctcttgaa gtcacctgcc agtctgaaag cccatacctg caaacaggac ttgagcaata
     1261 ccacagaact agccacaatc agtagcgtaa atattgacat cttacctgca aaagggaggg
     1321 attcagtgag tgatggcttt gttcaggaga atcagccaag atatttggat gcctctaatg
     1381 agttaggagg tatatgcagt atttctcaag tggaagagga gatgctgcag gacaacacta
     1441 aatccagtgc ccagcctgaa aacctgattc ccatgtggtc ctctgacatt gtcactgggg
     1501 aaaagaatga accagtgaag cctctgcagc ccctaatcaa agaacaaaag ccaaaggacc
     1561 aggatcaagt tgctggtgaa tgtattatag aaaaacaggg cagaatccac ccagatttac
     1621 agccacacaa ctctgggtct gaaccttccc tgtctcgaca gcgacggcaa aagaggagag
     1681 aacagactga gcacagaggg gaaaagagac aggtccgcag agatctcttt gctttccaag
     1741 agtcgcctcc tcgatttttg ccttctcatc ccattgttgg gaaagtggat gtcacatcaa
     1801 cacaaaaaga ggctgaaaac caacgtagag tggtcactgg gtctgtgagc agttcaagga
     1861 gcagtgagat gtcatcatca aaggatcgac cattatcagc cagagagagg aggcgactaa
     1921 agcagtcaca ggaagaaatg tcctcttcag gcccttcagt gaggaaagcg tctctgagtg
     1981 tagcagggcc aggaaaaccc caggaagaag accagccctt gcctgcccga cggctctcct
     2041 ctgactgcag cgtcactcag gtgatccttt aaagcacttt aacagtctca cattaagagc
     2101 aagctgaagc tgggcatggt ggcttgtggg tgttatctca gctacttggg aggccaagga
     2161 aggaggattg cttgagccca ggagtttgtg gccagcctgg acaacatagt gacacccctg
     2221 tatccaaaaa aaagaaaaaa aaaaagacaa gctgagtttg cctaggtaat ttaaaatgcc
     2281 aacattccta tagaacaagc cttctgctta ggagttgata aaccagaact agccatccac
     2341 tgtcctctgg aaatttcttc acagctgaga ctctccagga cctttgtaaa acttcacctt
     2401 gggcaggcgc ggtagctcat gcctgtaatc ccggcacttt gggaggctga ggcaggcgga
     2461 tcatgaggtc aagagttgga gaccagcctg gccaacatgg tgaaaccctg tctctactaa
     2521 aaatacaaaa attagctggg cgttgcggca cgtgcctgta atcccagcta ctcgggaggc
     2581 tgaggcagga aaatcacttg aaccagagag tcggaagttg ctgtgagccg agatcgtgcc
     2641 actgcactct agcctggcga cagagcaaga ctctgtctca aaaaaacaca aaaatcaaaa
     2701 caaaaaaaaa acaaacaaaa taaaaaactt catctga
//
