LOCUS       XM_017007085            4441 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens NIMA related kinase 4 (NEK4), transcript
            variant X1, mRNA.
ACCESSION   XM_017007085
VERSION     XM_017007085.2
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000003.12) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Apr 5, 2022 this sequence version replaced XM_017007085.1.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4441
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="3"
     gene            1..4441
                     /gene="NEK4"
                     /gene_synonym="NRK2; pp12301; STK2"
                     /note="NIMA related kinase 4; Derived by automated
                     computational analysis using gene prediction method:
                     Gnomon. Supporting evidence includes similarity to: 1
                     mRNA, 150 ESTs, 127 long SRA reads, 1 Protein, and 89%
                     coverage of the annotated genomic feature by RNAseq
                     alignments, including 9 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:6787"
                     /db_xref="HGNC:HGNC:11399"
                     /db_xref="MIM:601959"
     CDS             195..2807
                     /gene="NEK4"
                     /gene_synonym="NRK2; pp12301; STK2"
                     /codon_start=1
                     /product="serine/threonine-protein kinase Nek4 isoform X1"
                     /protein_id="XP_016862574.1"
                     /db_xref="GeneID:6787"
                     /db_xref="HGNC:HGNC:11399"
                     /db_xref="MIM:601959"
                     /translation="MPLAAYCYLRVVGKGSYGEVTLVKHRRDGKQYVIKKLNLRNASS
                     RERRAAEQEAQLLSQLKHPNIVTYKESWEGGDGLLYIVMGFCEGGDLYRKLKEQKGQL
                     LPENQVVEWFVQIAMALQYLHEKHILHRDLKTQNVFLTRTNIIKVGDLGIARVLENHC
                     DMASTLIGTPYYMSPELFSNKPYNYKSDVWALGCCVYEMATLKHAFNAKDMNSLVYRI
                     IEGKLPPMPRDYSPELAELIRTMLSKRPEERPSVRSILRQPYIKRQISFFLEATKIKT
                     SKNNIKNGDSQSKPFATVVSGEAESNHEVIHPQPLSSEGSQTYIMGEGKCLSQEKPRA
                     SGLLKSPASLKAHTCKQDLSNTTELATISSVNIDILPAKGRDSVSDGFVQENQPRYLD
                     ASNELGGICSISQVEEEMLQDNTKSSAQPENLIPMWSSDIVTGEKNEPVKPLQPLIKE
                     QKPKDQSLALSPKLECSGTILAHSNLRLLGSSDSPASASRVAGITGVCHHAQDQVAGE
                     CIIEKQGRIHPDLQPHNSGSEPSLSRQRRQKRREQTEHRGEKRQVRRDLFAFQESPPR
                     FLPSHPIVGKVDVTSTQKEAENQRRVVTGSVSSSRSSEMSSSKDRPLSARERRRLKQS
                     QEEMSSSGPSVRKASLSVAGPGKPQEEDQPLPARRLSSDCSVTQERKQIHCLSEDELS
                     SSTSSTDKSDGDYGEGKGQTNEINALVQLMTQTLKLDSKESCEDVPVANPVSEFKLHR
                     KYRDTLILHGKVAEEAEEIHFKELPSAIMPGSEKIRRLVEVLRTDVIRGLGVQLLEQV
                     YDLLEEEDEFDRELLPVFTPLMHSLPSGLFAIFTLQSPELSLCLQHGDNAQVRKTDSQ
                     KDQVPVVLLHHFPV"
     polyA_site      4441
                     /gene="NEK4"
                     /gene_synonym="NRK2; pp12301; STK2"
                     /experiment="COORDINATES: polyA evidence [ECO:0006239]"
ORIGIN      
        1 agaactgctc ccggcccgga tcgctatggc agcggcgtcg tcgcgggccg ggccccagca
       61 atcccgcccg ggcccggctg cctcaacagc cgcccccact gccccctctc gggcatgaac
      121 cgagcttctt gttgccgccc gctgccctac ccgccgctgc cgccgcatcc cgactctggg
      181 ccagcgctgg gaacatgccc ctggccgcct actgctacct gcgggtcgtg ggcaagggga
      241 gctatggaga ggtgacgctt gtgaagcacc ggcgggacgg caagcagtat gtcatcaaaa
      301 aactgaacct ccgaaatgcc tctagccgag agcggcgagc tgctgaacag gaagcccagc
      361 tcttgtctca gttgaagcat cccaacattg tcacctacaa ggagtcatgg gaaggaggag
      421 atggtctgct ctacattgtc atgggcttct gtgaaggagg tgatttgtac cgaaagctca
      481 aggagcagaa agggcagctt ctgcctgaga atcaggtggt agagtggttt gtacagatcg
      541 ccatggcttt gcagtattta catgaaaaac acatccttca tcgagatctg aaaactcaaa
      601 atgtcttcct aacaagaaca aacatcatca aagtagggga cctaggaatt gcccgagtgt
      661 tagagaacca ctgtgacatg gctagcaccc tcattggcac accctactac atgagccctg
      721 aattgttctc aaacaaaccc tacaactata agtctgatgt ttgggctcta ggatgctgtg
      781 tctatgaaat ggccaccttg aagcatgctt tcaatgcaaa agatatgaat tctttagttt
      841 atcggattat tgaaggaaag ctgccaccaa tgccaagaga ttacagccca gagctggcag
      901 aactgataag aacaatgctg agcaaaaggc ctgaagaaag gccgtctgtg aggagcatcc
      961 tgaggcagcc ttatataaag cggcaaatct ccttcttttt ggaggccaca aagataaaaa
     1021 cctccaaaaa taacattaaa aatggtgact ctcaatccaa gccttttgct acagtggttt
     1081 ctggagaggc agaatcaaat catgaagtaa tccaccccca accactctct tctgagggct
     1141 cccagacata tataatgggt gaaggcaaat gtttgtccca ggagaaaccc agggcctctg
     1201 gtctcttgaa gtcacctgcc agtctgaaag cccatacctg caaacaggac ttgagcaata
     1261 ccacagaact agccacaatc agtagcgtaa atattgacat cttacctgca aaagggaggg
     1321 attcagtgag tgatggcttt gttcaggaga atcagccaag atatttggat gcctctaatg
     1381 agttaggagg tatatgcagt atttctcaag tggaagagga gatgctgcag gacaacacta
     1441 aatccagtgc ccagcctgaa aacctgattc ccatgtggtc ctctgacatt gtcactgggg
     1501 aaaagaatga accagtgaag cctctgcagc ccctaatcaa agaacaaaag ccaaaggacc
     1561 agagtcttgc cctgtcgccc aagctggagt gcagtggcac aatcttggct cacagcaacc
     1621 tccgcctcct gggttcaagt gattctccag cctcagcctc ccgagtagct gggattacag
     1681 gcgtgtgcca ccacgcccag gatcaagttg ctggtgaatg tattatagaa aaacagggca
     1741 gaatccaccc agatttacag ccacacaact ctgggtctga accttccctg tctcgacagc
     1801 gacggcaaaa gaggagagaa cagactgagc acagagggga aaagagacag gtccgcagag
     1861 atctctttgc tttccaagag tcgcctcctc gatttttgcc ttctcatccc attgttggga
     1921 aagtggatgt cacatcaaca caaaaagagg ctgaaaacca acgtagagtg gtcactgggt
     1981 ctgtgagcag ttcaaggagc agtgagatgt catcatcaaa ggatcgacca ttatcagcca
     2041 gagagaggag gcgactaaag cagtcacagg aagaaatgtc ctcttcaggc ccttcagtga
     2101 ggaaagcgtc tctgagtgta gcagggccag gaaaacccca ggaagaagac cagcccttgc
     2161 ctgcccgacg gctctcctct gactgcagcg tcactcagga aaggaaacag attcattgtc
     2221 tgtctgagga tgagttaagt tcttctacaa gttcaactga taagtcagat ggggattacg
     2281 gggaagggaa aggtcagaca aatgaaatta atgccttggt acaattgatg actcagaccc
     2341 tgaaactgga ttctaaagag agctgtgaag atgtcccggt agcaaaccca gtgtcagaat
     2401 tcaaacttca tcggaaatat cgggacacac tgatacttca tgggaaggtt gcagaagagg
     2461 cagaggaaat ccattttaaa gagctacctt cagctattat gccaggttct gaaaagatca
     2521 ggagactagt tgaagtcttg agaactgatg taattcgtgg cctgggagtt cagcttttag
     2581 agcaggtgta tgatcttttg gaggaggagg atgaatttga tagagagctt ctccctgtgt
     2641 tcacaccttt gatgcattcc ctgccatctg gattgtttgc tatcttcacc ctgcagagtc
     2701 cagagctctc gctttgtctc caacatggag ataatgctca ggtcaggaag acagattccc
     2761 agaaagacca ggttcctgta gttctcctac atcacttccc tgtataaagc cctctgtgca
     2821 gggtccagtt atttccactc ctcctgagag aattctgtag ccacatccat gaatgtcaag
     2881 tgacgctgag taagagtctt tcctgattcc ttttctttcc gcttctttct cttctgggct
     2941 tcttcatcac acagcctgac tcataagaaa tcaatctgtg gccgggtgtg gtggctcacg
     3001 cctgtaatcc caacaccttg ggaggccgag atgggcggat catgaggtca ggagattgag
     3061 accatcctga cttaacacgg tgaaaccccg tctctactaa aaatacaaaa aaattagccg
     3121 ggcgcagtgg cgggcatctg tagtcccaac tacttgggag gctgaggcag gagaatggca
     3181 tgaacccagg aggcggagct tgcagtgagc caagatcgcg ccactgcact cagcctgggc
     3241 aactgagaga gactgtgtct caaaaagaaa aaaaaagaaa tcaatctgtg aggctgggcg
     3301 ctgggtggct catgcctgta atcccagcat gtgttagtct gttctcacac tgctaataaa
     3361 gacatacttg agattgggta gtttataaag aaaagaggat taattgactc atggttccat
     3421 atggctgggg aggccttaac aatcatagca gatggtgaag gggaagcaag acacgtctta
     3481 cgtggcagca ggcaagagag tgtgtgcagg gggactgccc ttcataaaac cgtcagatct
     3541 cgtgagactt actcactatc atgagaaccg catgggaaaa cccgtcccca tgattcactt
     3601 acctcccgcc gggtccctcc cacgacacgt ggggattatg ggagatacaa ttcaagatga
     3661 gatttgggtg gagacacagc taaaccatac tttcggagga cgaggtgggc agattgcctg
     3721 aactcagaag tttgagacgg gcctgggcaa catggcaaga ctcctgtgtg tgctgcggca
     3781 tgaccttcac tccacgtgat ccacttccag gtctcattgg acacattttg agttaattct
     3841 tgcgtatggc atgatgaagt aaagctccaa cttcattatg tatgtggctc tcctgttgtc
     3901 ccgtcaccat gtgttgcaaa gactattttc tcaccttgtt aaaaatcagt tgactagaga
     3961 cacatgggct tatttctgga ctctcatttc tattccgctg atctatatat ctatccttat
     4021 gccactacca cactttgctt actgttactt tggagtaagg tttgaaatca ggaaggatga
     4081 gtcctccact attattcttt ctcaagattg ttttggttat tctgggtccc ttgcaattac
     4141 atatgaattt tagaatttgt ttgtcaattt ccacaaagaa gccagctgtc ttaaagaaat
     4201 tgagagaaga aagaaaagta tgtttgtaaa ttttgttgtt gtaactctat catttctgga
     4261 tctctttatt tgttcctttg gattcaactt tccatgtgga gtcatttccg tagcctaata
     4321 cagctttgct cccacttacc tcctttgttt tgttattggc aaatatatta catttctata
     4381 tgttataggc tcaacaatat atacattttt ttaaattgta ataaaatgga gataaaatat
     4441 a
//
