LOCUS       NM_001164508           26191 bp    mRNA    linear   PRI 05-OCT-2024
DEFINITION  Homo sapiens nebulin (NEB), transcript variant 2, mRNA.
ACCESSION   NM_001164508
VERSION     NM_001164508.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 26191)
  AUTHORS   Karimi,E., Gohlke,J., van der Borgh,M., Lindqvist,J., Hourani,Z.,
            Kolb,J., Cossette,S., Lawlor,M.W., Ottenheijm,C. and Granzier,H.
  TITLE     Characterization of NEB pathogenic variants in patients reveals
            novel nemaline myopathy disease mechanisms and omecamtiv mecarbil
            force effects
  JOURNAL   Acta Neuropathol 147 (1), 72 (2024)
   PUBMED   38634969
  REMARK    GeneRIF: Characterization of NEB pathogenic variants in patients
            reveals novel nemaline myopathy disease mechanisms and omecamtiv
            mecarbil force effects.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26191)
  AUTHORS   Jackson,M., Thomas,M.A., Suchet,I., Mahallati,H., Kuret,V. and
            Lauzon,J.
  TITLE     Lethal multiple pterygium syndrome, large cystic hygroma, and cleft
            palate: Rare and severe fetal presentations of RYR1- and
            NEB-related congenital myopathies
  JOURNAL   Prenat Diagn 44 (4), 522-526 (2024)
   PUBMED   38520674
  REMARK    GeneRIF: Lethal multiple pterygium syndrome, large cystic hygroma,
            and cleft palate: Rare and severe fetal presentations of RYR1- and
            NEB-related congenital myopathies.
REFERENCE   3  (bases 1 to 26191)
  AUTHORS   Lehtokari,V.L., Pelin,K., Sandbacka,M., Ranta,S., Donner,K.,
            Muntoni,F., Sewry,C., Angelini,C., Bushby,K., Van den Bergh,P.,
            Iannaccone,S., Laing,N.G. and Wallgren-Pettersson,C.
  TITLE     Identification of 45 novel mutations in the nebulin gene associated
            with autosomal recessive nemaline myopathy
  JOURNAL   Hum Mutat 27 (9), 946-956 (2006)
   PUBMED   16917880
  REMARK    GeneRIF: 45 novel mutations within the nubulin gene are associated
            with nemaline myopathy.
REFERENCE   4  (bases 1 to 26191)
  AUTHORS   Donner,K., Sandbacka,M., Lehtokari,V.L., Wallgren-Pettersson,C. and
            Pelin,K.
  TITLE     Complete genomic structure of the human nebulin gene and
            identification of alternatively spliced transcripts
  JOURNAL   Eur J Hum Genet 12 (9), 744-751 (2004)
   PUBMED   15266303
REFERENCE   5  (bases 1 to 26191)
  AUTHORS   McElhinny,A.S., Kazmierski,S.T., Labeit,S. and Gregorio,C.C.
  TITLE     Nebulin: the nebulous, multifunctional giant of striated muscle
  JOURNAL   Trends Cardiovasc Med 13 (5), 195-201 (2003)
   PUBMED   12837582
  REMARK    Review article
REFERENCE   6  (bases 1 to 26191)
  AUTHORS   Labeit,S. and Kolmerer,B.
  TITLE     The complete primary structure of human nebulin and its correlation
            to muscle structure
  JOURNAL   J Mol Biol 248 (2), 308-315 (1995)
   PUBMED   7739042
REFERENCE   7  (bases 1 to 26191)
  AUTHORS   North,K.N. and Ryan,M.M.
  TITLE     Nemaline Myopathy - RETIRED CHAPTER, FOR HISTORICAL REFERENCE ONLY
  JOURNAL   (in) Adam MP, Feldman J, Mirzaa GM, Pagon RA, Wallace SE and
            Amemiya A (Eds.);
            GENEREVIEWS(R);
            (1993)
   PUBMED   20301465
REFERENCE   8  (bases 1 to 26191)
  AUTHORS   Jin,J.P. and Wang,K.
  TITLE     Cloning, expression, and protein interaction of human nebulin
            fragments composed of varying numbers of sequence modules
  JOURNAL   J Biol Chem 266 (31), 21215-21223 (1991)
   PUBMED   1682316
REFERENCE   9  (bases 1 to 26191)
  AUTHORS   Zeviani,M., Darras,B.T., Rizzuto,R., Salviati,G., Betto,R.,
            Bonilla,E., Miranda,A.F., Du,J., Samitt,C., Dickson,G. et al.
  TITLE     Cloning and expression of human nebulin cDNAs and assignment of the
            gene to chromosome 2q31-q32
  JOURNAL   Genomics 2 (3), 249-256 (1988)
   PUBMED   3397062
REFERENCE   10 (bases 1 to 26191)
  AUTHORS   Stedman,H., Browning,K., Oliver,N., Oronzi-Scott,M., Fischbeck,K.,
            Sarkar,S., Sylvester,J., Schmickel,R. and Wang,K.
  TITLE     Nebulin cDNAs detect a 25-kilobase transcript in skeletal muscle
            and localize to human chromosome 2
  JOURNAL   Genomics 2 (1), 1-7 (1988)
   PUBMED   2838409
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff in
            collaboration with Johan den Dunnen, Vilma-Lotta Lehtokari,
            Katarina Pelin, Tom Winder. The reference sequence was derived from
            AC107052.4, AC116650.4 and AC009497.3.
            
            On Aug 7, 2020 this sequence version replaced NM_001164508.1.
            
            Summary: This gene encodes nebulin, a giant protein component of
            the cytoskeletal matrix that coexists with the thick and thin
            filaments within the sarcomeres of skeletal muscle. In most
            vertebrates, nebulin accounts for 3 to 4% of the total myofibrillar
            protein. The encoded protein contains approximately 30-amino acid
            long modules that can be classified into 7 types and other repeated
            modules. Protein isoform sizes vary from 600 to 800 kD due to
            alternative splicing that is tissue-, species-,and developmental
            stage-specific. Of the 183 exons in the nebulin gene, at least 43
            are alternatively spliced, although exons 143 and 144 are not found
            in the same transcript. Of the several thousand transcript variants
            predicted for nebulin, the RefSeq Project has decided to create
            three representative RefSeq records. Mutations in this gene are
            associated with recessive nemaline myopathy. [provided by RefSeq,
            Sep 2009].
            
            Transcript Variant: This variant (2) represents a transcript with
            all known exons of the nebulin gene except for exon 143. The RefSeq
            Project created this record to better support clinical studies but
            the combination of exons and splice sites still needs to be
            experimentally confirmed. The predicted protein (isoform 2) is the
            same length as isoform 1 but has a different sequence due to the
            exchange of exon 143 for exon 144.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            RNAseq introns :: mixed sample support SAMEA1965299, SAMEA1966682
                              [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            inferred exon combination :: based on alignments, homology
            MANE Ensembl match        :: ENST00000397345.8/ ENSP00000380505.3
            RefSeq Select criteria    :: based on manual assertion, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-79                AC107052.4         127897-127975       c
            80-163              AC107052.4         127211-127294       c
            164-228             AC107052.4         126620-126684       c
            229-270             AC107052.4         123114-123155       c
            271-486             AC107052.4         121190-121405       c
            487-594             AC107052.4         118952-119059       c
            595-699             AC107052.4         118356-118460       c
            700-804             AC107052.4         117759-117863       c
            805-909             AC107052.4         116881-116985       c
            910-1014            AC107052.4         110915-111019       c
            1015-1119           AC107052.4         103933-104037       c
            1120-1227           AC107052.4         103155-103262       c
            1228-1344           AC107052.4         100380-100496       c
            1345-1449           AC107052.4         91043-91147         c
            1450-1557           AC107052.4         90849-90956         c
            1558-1662           AC107052.4         90647-90751         c
            1663-1761           AC107052.4         90136-90234         c
            1762-1866           AC107052.4         89077-89181         c
            1867-1974           AC107052.4         88021-88128         c
            1975-2088           AC107052.4         87822-87935         c
            2089-2190           AC107052.4         85760-85861         c
            2191-2298           AC107052.4         85558-85665         c
            2299-2403           AC107052.4         85363-85467         c
            2404-2502           AC107052.4         84226-84324         c
            2503-2607           AC107052.4         81791-81895         c
            2608-2715           AC107052.4         81125-81232         c
            2716-2829           AC107052.4         80918-81031         c
            2830-3027           AC107052.4         78277-78474         c
            3028-3135           AC107052.4         76161-76268         c
            3136-3234           AC107052.4         74229-74327         c
            3235-3339           AC107052.4         73417-73521         c
            3340-3447           AC107052.4         73220-73327         c
            3448-3759           AC107052.4         71375-71686         c
            3760-3966           AC107052.4         71064-71270         c
            3967-4071           AC107052.4         68786-68890         c
            4072-4179           AC107052.4         67976-68083         c
            4180-4491           AC107052.4         65868-66179         c
            4492-4698           AC107052.4         64522-64728         c
            4699-4803           AC107052.4         62526-62630         c
            4804-4911           AC107052.4         61303-61410         c
            4912-5223           AC107052.4         59589-59900         c
            5224-5430           AC107052.4         58832-59038         c
            5431-5535           AC107052.4         58258-58362         c
            5536-5643           AC107052.4         58000-58107         c
            5644-5955           AC107052.4         57047-57358         c
            5956-6162           AC107052.4         55634-55840         c
            6163-6267           AC107052.4         52564-52668         c
            6268-6375           AC107052.4         51482-51589         c
            6376-6687           AC107052.4         49652-49963         c
            6688-6894           AC107052.4         49316-49522         c
            6895-6999           AC107052.4         48769-48873         c
            7000-7107           AC107052.4         47491-47598         c
            7108-7419           AC107052.4         44073-44384         c
            7420-7623           AC107052.4         43675-43878         c
            7624-7728           AC107052.4         39629-39733         c
            7729-7836           AC107052.4         37967-38074         c
            7837-8148           AC107052.4         37317-37628         c
            8149-8352           AC107052.4         36649-36852         c
            8353-8457           AC107052.4         36264-36368         c
            8458-8565           AC107052.4         36073-36180         c
            8566-8877           AC107052.4         33854-34165         c
            8878-9081           AC107052.4         33356-33559         c
            9082-9186           AC107052.4         32779-32883         c
            9187-9294           AC107052.4         29726-29833         c
            9295-9606           AC107052.4         27153-27464         c
            9607-9810           AC107052.4         24642-24845         c
            9811-9915           AC107052.4         24214-24318         c
            9916-10023          AC107052.4         23038-23145         c
            10024-10335         AC107052.4         21022-21333         c
            10336-10539         AC107052.4         20501-20704         c
            10540-10644         AC107052.4         19033-19137         c
            10645-10752         AC107052.4         14418-14525         c
            10753-11064         AC107052.4         12950-13261         c
            11065-11268         AC107052.4         11774-11977         c
            11269-11373         AC107052.4         10863-10967         c
            11374-11481         AC107052.4         9501-9608           c
            11482-11793         AC107052.4         7775-8086           c
            11794-11997         AC107052.4         5685-5888           c
            11998-12102         AC107052.4         4261-4365           c
            12103-12210         AC107052.4         4015-4122           c
            12211-12522         AC107052.4         3308-3619           c
            12523-12726         AC107052.4         1972-2175           c
            12727-12831         AC107052.4         1003-1107           c
            12832-12939         AC107052.4         105-212             c
            12940-13251         AC116650.4         1837-2148           c
            13252-13455         AC116650.4         846-1049            c
            13456-13560         AC009497.3         180970-181074       c
            13561-13668         AC009497.3         180284-180391       c
            13669-13980         AC009497.3         178825-179136       c
            13981-14184         AC009497.3         176310-176513       c
            14185-14289         AC009497.3         175341-175445       c
            14290-14397         AC009497.3         174443-174550       c
            14398-14709         AC009497.3         172390-172701       c
            14710-14913         AC009497.3         171399-171602       c
            14914-15018         AC009497.3         170417-170521       c
            15019-15126         AC009497.3         169731-169838       c
            15127-15438         AC009497.3         168272-168583       c
            15439-15642         AC009497.3         165757-165960       c
            15643-15747         AC009497.3         164788-164892       c
            15748-15855         AC009497.3         163890-163997       c
            15856-16167         AC009497.3         161838-162149       c
            16168-16371         AC009497.3         160847-161050       c
            16372-16476         AC009497.3         159866-159970       c
            16477-16584         AC009497.3         159180-159287       c
            16585-16896         AC009497.3         157721-158032       c
            16897-17100         AC009497.3         154534-154737       c
            17101-17205         AC009497.3         154078-154182       c
            17206-17310         AC009497.3         148880-148984       c
            17311-17622         AC009497.3         148464-148775       c
            17623-17727         AC009497.3         147651-147755       c
            17728-17826         AC009497.3         147001-147099       c
            17827-17928         AC009497.3         146699-146800       c
            17929-18036         AC009497.3         146454-146561       c
            18037-18348         AC009497.3         145551-145862       c
            18349-18453         AC009497.3         144099-144203       c
            18454-18558         AC009497.3         143884-143988       c
            18559-18663         AC009497.3         143427-143531       c
            18664-18771         AC009497.3         142206-142313       c
            18772-18885         AC009497.3         141989-142102       c
            18886-19083         AC009497.3         140994-141191       c
            19084-19188         AC009497.3         140493-140597       c
            19189-19293         AC009497.3         139591-139695       c
            19294-19398         AC009497.3         139387-139491       c
            19399-19506         AC009497.3         138975-139082       c
            19507-19620         AC009497.3         133314-133427       c
            19621-19818         AC009497.3         132211-132408       c
            19819-19923         AC009497.3         131781-131885       c
            19924-20028         AC009497.3         131055-131159       c
            20029-20136         AC009497.3         130121-130228       c
            20137-20241         AC009497.3         128019-128123       c
            20242-20349         AC009497.3         126691-126798       c
            20350-20454         AC009497.3         126017-126121       c
            20455-20559         AC009497.3         125812-125916       c
            20560-20658         AC009497.3         124728-124826       c
            20659-20769         AC009497.3         124271-124381       c
            20770-20874         AC009497.3         119830-119934       c
            20875-20979         AC009497.3         119080-119184       c
            20980-21084         AC009497.3         118727-118831       c
            21085-21189         AC009497.3         116523-116627       c
            21190-21294         AC009497.3         116255-116359       c
            21295-21399         AC009497.3         115515-115619       c
            21400-21504         AC009497.3         114074-114178       c
            21505-21609         AC009497.3         111825-111929       c
            21610-21714         AC009497.3         110175-110279       c
            21715-21822         AC009497.3         109377-109484       c
            21823-21927         AC009497.3         107593-107697       c
            21928-22032         AC009497.3         105864-105968       c
            22033-22137         AC009497.3         105301-105405       c
            22138-22242         AC009497.3         104541-104645       c
            22243-22353         AC009497.3         104341-104451       c
            22354-22464         AC009497.3         103546-103656       c
            22465-22566         AC009497.3         102898-102999       c
            22567-22671         AC009497.3         102694-102798       c
            22672-22782         AC009497.3         98041-98151         c
            22783-22887         AC009497.3         97348-97452         c
            22888-22992         AC009497.3         96701-96805         c
            22993-23097         AC009497.3         94842-94946         c
            23098-23208         AC009497.3         93201-93311         c
            23209-23319         AC009497.3         92701-92811         c
            23320-23433         AC009497.3         91963-92076         c
            23434-23538         AC009497.3         91116-91220         c
            23539-23643         AC009497.3         86388-86492         c
            23644-23748         AC009497.3         85292-85396         c
            23749-23841         AC009497.3         84549-84641         c
            23842-23934         AC009497.3         83861-83953         c
            23935-24027         AC009497.3         81732-81824         c
            24028-24120         AC009497.3         81176-81268         c
            24121-24213         AC009497.3         79774-79866         c
            24214-24306         AC009497.3         77681-77773         c
            24307-24399         AC009497.3         76643-76735         c
            24400-24492         AC009497.3         76009-76101         c
            24493-24585         AC009497.3         75324-75416         c
            24586-24678         AC009497.3         74659-74751         c
            24679-24771         AC009497.3         72544-72636         c
            24772-24864         AC009497.3         72158-72250         c
            24865-24957         AC009497.3         71736-71828         c
            24958-25065         AC009497.3         70770-70877         c
            25066-25249         AC009497.3         70481-70664         c
            25250-25342         AC009497.3         70066-70158         c
            25343-25489         AC009497.3         68755-68901         c
            25490-25596         AC009497.3         68354-68460         c
            25597-26191         AC009497.3         63722-64316         c
FEATURES             Location/Qualifiers
     source          1..26191
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="2"
                     /map="2q23.3"
     gene            1..26191
                     /gene="NEB"
                     /gene_synonym="AMC6; NEB177D; NEM2"
                     /note="nebulin"
                     /db_xref="GeneID:4703"
                     /db_xref="HGNC:HGNC:7720"
                     /db_xref="MIM:161650"
     exon            1..79
                     /gene="NEB"
                     /gene_synonym="AMC6; NEB177D; NEM2"
                     /inference="alignment:Splign:2.1.0"
     exon            80..163
                     /gene="NEB"
                     /gene_synonym="AMC6; NEB177D; NEM2"
                     /inference="alignment:Splign:2.1.0"
     exon            164..228
                     /gene="NEB"
                     /gene_synonym="AMC6; NEB177D; NEM2"
                     /inference="alignment:Splign:2.1.0"
     CDS             193..25770
                     /gene="NEB"
                     /gene_synonym="AMC6; NEB177D; NEM2"
                     /note="isoform 2 is encoded by transcript variant 2;
                     nemaline myopathy type 2"
                     /codon_start=1
                     /product="nebulin isoform 2"
                     /protein_id="NP_001157980.2"
                     /db_xref="CCDS:CCDS54407.1"
                     /db_xref="GeneID:4703"
                     /db_xref="HGNC:HGNC:7720"
                     /db_xref="MIM:161650"
                     /translation="MADDEDYEEVVEYYTEEVVYEEVPGETITKIYETTTTRTSDYEQ
                     SETSKPALAQPALAQPASAKPVERRKVIRKKVDPSKFMTPYIAHSQKMQDLFSPNKYK
                     EKFEKTKGQPYASTTDTPELRRIKKVQDQLSEVKYRMDGDVAKTICHVDEKAKDIEHA
                     KKVSQQVSKVLYKQNWEDTKDKYLLPPDAPELVQAVKNTAMFSKKLYTEDWEADKSLF
                     YPYNDSPELRRVAQAQKALSDVAYKKGLAEQQAQFTPLADPPDIEFAKKVTNQVSKQK
                     YKEDYENKIKGKWSETPCFEVANARMNADNISTRKYQEDFENMKDQIYFMQTETPEYK
                     MNKKAGVAASKVKYKEDYEKNKGKADYNVLPASENPQLRQLKAAGDALSDKLYKENYE
                     KTKAKSINYCETPKFKLDTVLQNFSSDKKYKDSYLKDILGHYVGSFEDPYHSHCMKVT
                     AQNSDKNYKAEYEEDRGKGFFPQTITQEYEAIKKLDQCKDHTYKVHPDKTKFTQVTDS
                     PVLLQAQVNSKQLSDLNYKAKHESEKFKCHIPPDTPAFIQHKVNAYNLSDNLYKQDWE
                     KSKAKKFDIKVDAIPLLAAKANTKNTSDVMYKKDYEKNKGKMIGVLSINDDPKMLHSL
                     KVAKNQSDRLYKENYEKTKAKSMNYCETPKYQLDTQLKNFSEARYKDLYVKDVLGHYV
                     GSMEDPYHTHCMKVAAQNSDKSYKAEYEEDKGKCYFPQTITQEYEAIKKLDQCKDHTY
                     KVHPDKTKFTAVTDSPVLLQAQLNTKQLSDLNYKAKHEGEKFKCHIPADAPQFIQHRV
                     NAYNLSDNVYKQDWEKSKAKKFDIKVDAIPLLAAKANTKNTSDVMYKKDYEKSKGKMI
                     GALSINDDPKMLHSLKTAKNQSDREYRKDYEKSKTIYTAPLDMLQVTQAKKSQAIASD
                     VDYKHILHSYSYPPDSINVDLAKKAYALQSDVEYKADYNSWMKGCGWVPFGSLEMEKA
                     KRASDILNEKKYRQHPDTLKFTSIEDAPITVQSKINQAQRSDIAYKAKGEEIIHKYNL
                     PPDLPQFIQAKVNAYNISENMYKADLKDLSKKGYDLRTDAIPIRAAKAARQAASDVQY
                     KKDYEKAKGKMVGFQSLQDDPKLVHYMNVAKIQSDREYKKDYEKTKSKYNTPHDMFNV
                     VAAKKAQDVVSNVNYKHSLHHYTYLPDAMDLELSKNMMQIQSDNVYKEDYNNWMKGIG
                     WIPIGSLDVEKVKKAGDALNEKKYRQHPDTLKFTSIVDSPVMVQAKQNTKQVSDILYK
                     AKGEDVKHKYTMSPDLPQFLQAKCNAYNISDVCYKRDWYDLIAKGNNVLGDAIPITAA
                     KASRNIASDYKYKEAYEKSKGKHVGFRSLQDDPKLVHYMNVAKLQSDREYKKNYENTK
                     TSYHTPGDMVSITAAKMAQDVATNVNYKQPLHHYTYLPDAMSLEHTRNVNQIQSDNVY
                     KDEYNSFLKGIGWIPIGSLEVEKVKKAGDALNERKYRQHPDTVKFTSVPDSMGMVLAQ
                     HNTKQLSDLNYKVEGEKLKHKYTIDPELPQFIQAKVNALNMSDAHYKADWKKTIAKGY
                     DLRPDAIPIVAAKSSRNIASDCKYKEAYEKAKGKQVGFLSLQDDPKLVHYMNVAKIQS
                     DREYKKGYEASKTKYHTPLDMVSVTAAKKSQEVATNANYRQSYHHYTLLPDALNVEHS
                     RNAMQIQSDNLYKSDFTNWMKGIGWVPIESLEVEKAKKAGEILSEKKYRQHPEKLKFT
                     YAMDTMEQALNKSNKLNMDKRLYTEKWNKDKTTIHVMPDTPDILLSRVNQITMSDKLY
                     KAGWEEEKKKGYDLRPDAIAIKAARASRDIASDYKYKKAYEQAKGKHIGFRSLEDDPK
                     LVHFMQVAKMQSDREYKKGYEKSKTSFHTPVDMLSVVAAKKSQEVATNANYRNVIHTY
                     NMLPDAMSFELAKNMMQIQSDNQYKADYADFMKGIGWLPLGSLEAEKNKKAMEIISEK
                     KYRQHPDTLKYSTLMDSMNMVLAQNNAKIMNEHLYKQAWEADKTKVHIMPDIPQIILA
                     KANAINMSDKLYKLSLEESKKKGYDLRPDAIPIKAAKASRDIASDYKYKYNYEKGKGK
                     MVGFRSLEDDPKLVHSMQVAKMQSDREYKKNYENTKTSYHTPADMLSVTAAKDAQANI
                     TNTNYKHLIHKYILLPDAMNIELTRNMNRIQSDNEYKQDYNEWYKGLGWSPAGSLEVE
                     KAKKATEYASDQKYRQHPSNFQFKKLTDSMDMVLAKQNAHTMNKHLYTIDWNKDKTKI
                     HVMPDTPDILQAKQNQTLYSQKLYKLGWEEALKKGYDLPVDAISVQLAKASRDIASDY
                     KYKQGYRKQLGHHVGFRSLQDDPKLVLSMNVAKMQSEREYKKDFEKWKTKFSSPVDML
                     GVVLAKKCQELVSDVDYKNYLHQWTCLPDQNDVVQAKKVYELQSENLYKSDLEWLRGI
                     GWSPLGSLEAEKNKRASEIISEKKYRQPPDRNKFTSIPDAMDIVLAKTNAKNRSDRLY
                     REAWDKDKTQIHIMPDTPDIVLAKANLINTSDKLYRMGYEELKRKGYDLPVDAIPIKA
                     AKASREIASEYKYKEGFRKQLGHHIGARNIEDDPKMMWSMHVAKIQSDREYKKDFEKW
                     KTKFSSPVDMLGVVLAKKCQTLVSDVDYKNYLHQWTCLPDQSDVIHARQAYDLQSDNL
                     YKSDLQWLKGIGWMTSGSLEDEKNKRATQILSDHVYRQHPDQFKFSSLMDSIPMVLAK
                     NNAITMNHRLYTEAWDKDKTTVHIMPDTPEVLLAKQNKVNYSEKLYKLGLEEAKRKGY
                     DMRVDAIPIKAAKASRDIASEFKYKEGYRKQLGHHIGARAIRDDPKMMWSMHVAKIQS
                     DREYKKDFEKWKTKFSSPVDMLGVVLAKKCQTLVSDVDYKNYLHQWTCLPDQSDVIHA
                     RQAYDLQSDNMYKSDLQWMRGIGWVSIGSLDVEKCKRATEILSDKIYRQPPDRFKFTS
                     VTDSLEQVLAKNNAITMNKRLYTEAWDKDKTQIHIMPDTPEIMLARMNKINYSESLYK
                     LANEEAKKKGYDLRSDAIPIVAAKASRDIISDYKYKDGYCKQLGHHIGARNIEDDPKM
                     MWSMHVAKIQSDREYKKDFEKWKTKFSSPVDMLGVVLAKKCQTLVSDVDYKNYLHEWT
                     CLPDQSDVIHARQAYDLQSDNIYKSDLQWLRGIGWVPIGSMDVVKCKRATEILSDNIY
                     RQPPDKLKFTSVTDSLEQVLAKNNALNMNKRLYTEAWDKDKTQIHIMPDTPEIMLARQ
                     NKINYSETLYKLANEEAKKKGYDLRSDAIPIVAAKASRDVISDYKYKDGYRKQLGHHI
                     GARNIEDDPKMMWSMHVAKIQSDREYKKDFEKWKTKFSSPVDMLGVVLAKKCQTLVSD
                     VDYKNYLHEWTCLPDQNDVIHARQAYDLQSDNIYKSDLQWLRGIGWVPIGSMDVVKCK
                     RAAEILSDNIYRQPPDKLKFTSVTDSLEQVLAKNNALNMNKRLYTEAWDKDKTQVHIM
                     PDTPEIMLARQNKINYSESLYRQAMEEAKKEGYDLRSDAIPIVAAKASRDIASDYKYK
                     EAYRKQLGHHIGARAVHDDPKIMWSLHIAKVQSDREYKKDFEKYKTRYSSPVDMLGIV
                     LAKKCQTLVSDVDYKHPLHEWICLPDQNDIIHARKAYDLQSDNLYKSDLEWMKGIGWV
                     PIDSLEVVRAKRAGELLSDTIYRQRPETLKFTSITDTPEQVLAKNNALNMNKRLYTEA
                     WDNDKKTIHVMPDTPEIMLAKLNRINYSDKLYKLALEESKKEGYDLRLDAIPIQAAKA
                     SRDIASDYKYKEGYRKQLGHHIGARNIKDDPKMMWSIHVAKIQSDREYKKEFEKWKTK
                     FSSPVDMLGVVLAKKCQILVSDIDYKHPLHEWTCLPDQNDVIQARKAYDLQSDAIYKS
                     DLEWLRGIGWVPIGSVEVEKVKRAGEILSDRKYRQPADQLKFTCITDTPEIVLAKNNA
                     LTMSKHLYTEAWDADKTSIHVMPDTPDILLAKSNSANISQKLYTKGWDESKMKDYDLR
                     ADAISIKSAKASRDIASDYKYKEAYEKQKGHHIGAQSIEDDPKIMCAIHAGKIQSERE
                     YKKEFQKWKTKFSSPVDMLSILLAKKCQTLVTDIDYRNYLHEWTCMPDQNDIIQAKKA
                     YDLQSDSVYKADLEWLRGIGWMPEGSVEMNRVKVAQDLVNERLYRTRPEALSFTSIVD
                     TPEVVLAKANSLQISEKLYQEAWNKDKSNITIPSDTPEMLQAHINALQISNKLYQKDW
                     NDAKQKGYDIRADAIEIKHAKASREIASEYKYKEGYRKQLGHHMGFRTLQDDPKSVWA
                     IHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLVSDIDYRNYLHQWTCLP
                     DQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWLPEGSVEVMRVKNAQNLLNERLYRIK
                     PEALKFTSIVDTPEVIQAKINAVQISEPLYRDAWEKEKANVNVPADTPLMLQSKINAL
                     QISNKRYQQAWEDVKMTGYDLRADAIGIQHAKASRDIASDYLYKTAYEKQKGHYIGCR
                     SAKEDPKLVWAANVLKMQNDRLYKKAYNDHKAKISIPVDMVSISAAKEGQALASDVDY
                     RHYLHHWSCFPDQNDVIQARKAYDLQSDSVYKADLEWLRGIGWMPEGSVEMNRVKVAQ
                     DLVNERLYRTRPEALSFTSIVDTPEVVLAKANSLQISEKLYQEAWNKDKSNITIPSDT
                     PEMLQAHINALQISNKLYQKDWNDTKQKGYDIRADAIEIKHAKASREIASEYKYKEGY
                     RKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAK
                     KCQVLVSDIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWLPEG
                     SVEVMRVKNAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEPLYRNAWEK
                     EKANVNVPADTPLMLQSKINALQISNKRYQQAWEDVKMTGYDLRADAIGIQHAKASRD
                     IASDYLYKTAYEKQKGHYIGCRSAKEDPKLVWAANVLKMQNDRLYKKAYNDHKAKISI
                     PVDMVSISAAKEGQALASDVDYRHYLHHWSCFPDQNDVIQARKAYDLQSDSVYKADLE
                     WLRGIGWMPEGSVEMNRVKVAQDLVNERLYRTRPEALSFTSIVDTPEVVLAKANSLQI
                     SEKLYQEAWNKDKSNITIPSDTPEMLQAHINALQISNKLYQKDWNDTKQKGYDIRADA
                     IEIKHAKASREIASEYKYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKK
                     AYEKSKGIHNTPLDMMSIVQAKKCQVLVSDIDYRNYLHQWTCLPDQNDVIQAKKAYDL
                     QSDNLYKSDLEWLKGIGWLPEGSVEVMRVKNAQNLLNERLYRIKPEALKFTSIVDTPE
                     VIQAKINAVQISEPLYRDAWEKEKANVNVPADTPLMLQSKINALQISNKRYQQAWEDV
                     KMTGYDLRADAIGIQHAKASRDIASDYLYKTAYEKQKGHYIGCRSAKEDPKLVWAANV
                     LKMQNDRLYKKAYNDHKAKISIPVDMVSISAAKEGQALASDVDYRHYLHRWSCFPDQN
                     DVIQARKAYDLQSDALYKADLEWLRGIGWMPQGSPEVLRVKNAQNIFCDSVYRTPVVN
                     LKYTSIVDTPEVVLAKSNAENISIPKYREVWDKDKTSIHIMPDTPEINLARANALNVS
                     NKLYREGWDEMKAGCDVRLDAIPIQAAKASREIASDYKYKLDHEKQKGHYVGTLTARD
                     DNKIRWALIADKLQNEREYRLDWAKWKAKIQSPVDMLSILHSKNSQALVSDMDYRNYL
                     HQWTCMPDQNDVIQAKKAYELQSDNVYKADLEWLRGIGWMPNDSVSVNHAKHAADIFS
                     EKKYRTKIETLNFTPVDDRVDYVTAKQSGEILDDIKYRKDWNATKSKYTLTETPLLHT
                     AQEAARILDQYLYKEGWERQKATGYILPPDAVPFVHAHHCNDVQSELKYKAEHVKQKG
                     HYVGVPTMRDDPKLVWFEHAGQIQNERLYKEDYHKTKAKINIPADMVSVLAAKQGQTL
                     VSDIDYRNYLHQWMCHPDQNDVIQARKAYDLQSDNVYRADLEWLRGIGWIPLDSVDHV
                     RVTKNQEMMSQIKYKKNALENYPNFRSVVDPPEIVLAKINSVNQSDVKYKETFNKAKG
                     KYTFSPDTPHISHSKDMGKLYSTILYKGAWEGTKAYGYTLDERYIPIVGAKHADLVNS
                     ELKYKETYEKQKGHYLAGKVIGEFPGVVHCLDFQKMRSALNYRKHYEDTKANVHIPND
                     MMNHVLAKRCQYILSDLEYRHYFHQWTSLLEEPNVIRVRNAQEILSDNVYKDDLNWLK
                     GIGCYVWDTPQILHAKKSYDLQSQLQYTAAGKENLQNYNLVTDTPLYVTAVQSGINAS
                     EVKYKENYHQIKDKYTTVLETVDYDRTRNLKNLYSSNLYKEAWDRVKATSYILPSSTL
                     SLTHAKNQKHLASHIKYREEYEKFKALYTLPRSVDDDPNTARCLRVGKLNIDRLYRSV
                     YEKNKMKIHIVPDMVEMVTAKDSQKKVSEIDYRLRLHEWICHPDLQVNDHVRKVTDQI
                     SDIVYKDDLNWLKGIGCYVWDTPEILHAKHAYDLRDDIKYKAHMLKTRNDYKLVTDTP
                     VYVQAVKSGKQLSDAVYHYDYVHSVRGKVAPTTKTVDLDRALHAYKLQSSNLYKTSLR
                     TLPTGYRLPGDTPHFKHIKDTRYMSSYFKYKEAYEHTKAYGYTLGPKDVPFVHVRRVN
                     NVTSERLYRELYHKLKDKIHTTPDTPEIRQVKKTQEAVSELIYKSDFFKMQGHMISLP
                     YTPQVIHCRYVGDITSDIKYKEDLQVLKGFGCFLYDTPDMVRSRHLRKLWSNYLYTDK
                     ARKMRDKYKVVLDTPEYRKVQELKTHLSELVYRAAGKKQKSIFTSVPDTPDLLRAKRG
                     QKLQSQYLYVELATKERPHHHAGNQTTALKHAKDVKDMVSEKKYKIQYEKMKDKYTPV
                     PDTPILIRAKRAYWNASDLRYKETFQKTKGKYHTVKDALDIVYHRKVTDDISKIKYKE
                     NYMSQLGIWRSIPDRPEHFHHRAVTDTVSDVKYKEDLTWLKGIGCYAYDTPDFTLAEK
                     NKTLYSKYKYKEVFERTKSDFKYVADSPINRHFKYATQLMNERKYKSSAKMFLQHGCN
                     EILRPDMLTALYNSHMWSQIKYRKNYEKSKDKFTSIVDTPEHLRTTKVNKQISDILYK
                     LEYNKAKPRGYTTIHDTPMLLHVRKVKDEVSDLKYKEVYQRNKSNCTIEPDAVHIKAA
                     KDAYKVNTNLDYKKQYEANKAHWKWTPDRPDFLQAAKSSLQQSDFEYKLDREFLKGCK
                     LSVTDDKNTVLALRNTLIESDLKYKEKHVKERGTCHAVPDTPQILLAKTVSNLVSENK
                     YKDHVKKHLAQGSYTTLPETRDTVHVKEVTKHVSDTNYKKKFVKEKGKSNYSIMLEPP
                     EVKHAMEVAKKQSDVAYRKDAKENLHYTTVADRPDIKKATQAAKQASEVEYRAKHRKE
                     GSHGLSMLGRPDIEMAKKAAKLSSQVKYRENFDKEKGKTPKYNPKDSQLYKVMKDANN
                     LASEVKYKADLKKLHKPVTDMKESLIMNHVLNTSQLASSYQYKKKYEKSKGHYHTIPD
                     NLEQLHLKEATELQSIVKYKEKYEKERGKPMLDFETPTYITAKESQQMQSGKEYRKDY
                     EESIKGRNLTGLEVTPALLHVKYATKIASEKEYRKDLEESIRGKGLTEMEDTPDMLRA
                     KNATQILNEKEYKRDLELEVKGRGLNAMANETPDFMRARNATDIASQIKYKQSAEMEK
                     ANFTSVVDTPEIIHAQQVKNLSSQKKYKEDAEKSMSYYETVLDTPEIQRVRENQKNFS
                     LLQYQCDLKNSKGKITVVQDTPEILRVKENQKNFSSVLYKEDVSPGTAIGKTPEMMRV
                     KQTQDHISSVKYKEAIGQGTPIPDLPEVKRVKETQKHISSVMYKENLGTGIPTTVTPE
                     IERVKRNQENFSSVLYKENLGKGIPTPITPEMERVKRNQENFSSILYKENLSKGTPLP
                     VTPEMERVKLNQENFSSVLYKENVGKGIPIPITPEMERVKHNQENFSSVLYKENLGTG
                     IPIPITPEMQRVKHNQENLSSVLYKENMGKGTPLPVTPEMERVKHNQENISSVLYKEN
                     MGKGTPLPVTPEMERVKHNQENISSVLYKENMGKGTPLAVTPEMERVKHNQENISSVL
                     YKENVGKATATPVTPEMQRVKRNQENISSVLYKENLGKATPTPFTPEMERVKRNQENF
                     SSVLYKENMRKATPTPVTPEMERAKRNQENISSVLYSDSFRKQIQGKAAYVLDTPEMR
                     RVRETQRHISTVKYHEDFEKHKGCFTPVVTDPITERVKKNMQDFSDINYRGIQRKVVE
                     MEQKRNDQDQETITGLRVWRTNPGSVFDYDPAEDNIQSRSLHMINVQAQRRSREQSRS
                     ASALSISGGEEKSEHSEAPDHHLSTYSDGGVFAVSTAYKHAKTTELPQQRSSSVATQQ
                     TTVSSIPSHPSTAGKIFRAMYDYMAADADEVSFKDGDAIINVQAIDEGWMYGTVQRTG
                     RTGMLPANYVEAI"
     exon            229..270
                     /gene="NEB"
                     /gene_synonym="AMC6; NEB177D; NEM2"
                     /inference="alignment:Splign:2.1.0"
     exon            271..486
                     /gene="NEB"
                     /gene_synonym="AMC6; NEB177D; NEM2"
                     /inference="alignment:Splign:2.1.0"
     exon            487..594
                     /gene="NEB"
                     /gene_synonym="AMC6; NEB177D; NEM2"
                     /inference="alignment:Splign:2.1.0"
     exon            595..699
                     /gene="NEB"
                     /gene_synonym="AMC6; NEB177D; NEM2"
                     /inference="alignment:Splign:2.1.0"
     exon            700..804
                     /gene="NEB"
                     /gene_synonym="AMC6; NEB177D; NEM2"
                     /inference="alignment:Splign:2.1.0"
     exon            805..909
                     /gene="NEB"
                     /gene_synonym="AMC6; NEB177D; NEM2"
                     /inference="alignment:Splign:2.1.0"
     exon            910..1014
                     /gene="NEB"
                     /gene_synonym="AMC6; NEB177D; NEM2"
                     /inference="alignment:Splign:2.1.0"
     exon            1015..1119
                     /gene="NEB"
                     /gene_synonym="AMC6; NEB177D; NEM2"
                     /inference="alignment:Splign:2.1.0"
     exon            1120..1227
                     /gene="NEB"
                     /gene_synonym="AMC6; NEB177D; NEM2"
                     /inference="alignment:Splign:2.1.0"
     exon            1228..1344
                     /gene="NEB"
                     /gene_synonym="AMC6; NEB177D; NEM2"
                     /inference="alignment:Splign:2.1.0"
     exon            1345..1449
                     /gene="NEB"
                     /gene_synonym="AMC6; NEB177D; NEM2"
                     /inference="alignment:Splign:2.1.0"
     exon            1450..1557
                     /gene="NEB"
                     /gene_synonym="AMC6; NEB177D; NEM2"
                     /inference="alignment:Splign:2.1.0"
     exon            1558..1662
                     /gene="NEB"
                     /gene_synonym="AMC6; NEB177D; NEM2"
                     /inference="alignment:Splign:2.1.0"
     exon            1663..1761
                     /gene="NEB"
                     /gene_synonym="AMC6; NEB177D; NEM2"
                     /inference="alignment:Splign:2.1.0"
     exon            1762..1866
                     /gene="NEB"
                     /gene_synonym="AMC6; NEB177D; NEM2"
                     /inference="alignment:Splign:2.1.0"
     exon            1867..1974
                     /gene="NEB"
                     /gene_synonym="AMC6; NEB177D; NEM2"
                     /inference="alignment:Splign:2.1.0"
     exon            1975..2088
                     /gene="NEB"
                     /gene_synonym="AMC6; NEB177D; NEM2"
                     /inference="alignment:Splign:2.1.0"
     exon            2089..2190
                     /gene="NEB"
                     /gene_synonym="AMC6; NEB177D; NEM2"
                     /inference="alignment:Splign:2.1.0"
     exon            2191..2298
                     /gene="NEB"
                     /gene_synonym="AMC6; NEB177D; NEM2"
                     /inference="alignment:Splign:2.1.0"
     exon            2299..2403
                     /gene="NEB"
                     /gene_synonym="AMC6; NEB177D; NEM2"
                     /inference="alignment:Splign:2.1.0"
     exon            2404..2502
                     /gene="NEB"
                     /gene_synonym="AMC6; NEB177D; NEM2"
                     /inference="alignment:Splign:2.1.0"
     exon            2503..2607
                     /gene="NEB"
                     /gene_synonym="AMC6; NEB177D; NEM2"
                     /inference="alignment:Splign:2.1.0"
     exon            2608..2715
                     /gene="NEB"
                     /gene_synonym="AMC6; NEB177D; NEM2"
                     /inference="alignment:Splign:2.1.0"
     exon            2716..2829
                     /gene="NEB"
                     /gene_synonym="AMC6; NEB177D; NEM2"
                     /inference="alignment:Splign:2.1.0"
     exon            2830..3027
                     /gene="NEB"
                     /gene_synonym="AMC6; NEB177D; NEM2"
                     /inference="alignment:Splign:2.1.0"
     exon            3028..3135
                     /gene="NEB"
                     /gene_synonym="AMC6; NEB177D; NEM2"
                     /inference="alignment:Splign:2.1.0"
     exon            3136..3234
                     /gene="NEB"
                     /gene_synonym="AMC6; NEB177D; NEM2"
                     /inference="alignment:Splign:2.1.0"
     exon            3235..3339
                     /gene="NEB"
                     /gene_synonym="AMC6; NEB177D; NEM2"
                     /inference="alignment:Splign:2.1.0"
     exon            3340..3447
                     /gene="NEB"
                     /gene_synonym="AMC6; NEB177D; NEM2"
                     /inference="alignment:Splign:2.1.0"
     exon            3448..3759
                     /gene="NEB"
                     /gene_synonym="AMC6; NEB177D; NEM2"
                     /inference="alignment:Splign:2.1.0"
     exon            3760..3966
                     /gene="NEB"
                     /gene_synonym="AMC6; NEB177D; NEM2"
                     /inference="alignment:Splign:2.1.0"
     exon            3967..4071
                     /gene="NEB"
                     /gene_synonym="AMC6; NEB177D; NEM2"
                     /inference="alignment:Splign:2.1.0"
     exon            4072..4179
                     /gene="NEB"
                     /gene_synonym="AMC6; NEB177D; NEM2"
                     /inference="alignment:Splign:2.1.0"
     exon            4180..4491
                     /gene="NEB"
                     /gene_synonym="AMC6; NEB177D; NEM2"
                     /inference="alignment:Splign:2.1.0"
     exon            4492..4698
                     /gene="NEB"
                     /gene_synonym="AMC6; NEB177D; NEM2"
                     /inference="alignment:Splign:2.1.0"
     exon            4699..4803
                     /gene="NEB"
                     /gene_synonym="AMC6; NEB177D; NEM2"
                     /inference="alignment:Splign:2.1.0"
     exon            4804..4911
                     /gene="NEB"
                     /gene_synonym="AMC6; NEB177D; NEM2"
                     /inference="alignment:Splign:2.1.0"
     exon            4912..5223
                     /gene="NEB"
                     /gene_synonym="AMC6; NEB177D; NEM2"
                     /inference="alignment:Splign:2.1.0"
     exon            5224..5430
                     /gene="NEB"
                     /gene_synonym="AMC6; NEB177D; NEM2"
                     /inference="alignment:Splign:2.1.0"
     exon            5431..5535
                     /gene="NEB"
                     /gene_synonym="AMC6; NEB177D; NEM2"
                     /inference="alignment:Splign:2.1.0"
     exon            5536..5643
                     /gene="NEB"
                     /gene_synonym="AMC6; NEB177D; NEM2"
                     /inference="alignment:Splign:2.1.0"
     exon            5644..5955
                     /gene="NEB"
                     /gene_synonym="AMC6; NEB177D; NEM2"
                     /inference="alignment:Splign:2.1.0"
     exon            5956..6162
                     /gene="NEB"
                     /gene_synonym="AMC6; NEB177D; NEM2"
                     /inference="alignment:Splign:2.1.0"
     exon            6163..6267
                     /gene="NEB"
                     /gene_synonym="AMC6; NEB177D; NEM2"
                     /inference="alignment:Splign:2.1.0"
     exon            6268..6375
                     /gene="NEB"
                     /gene_synonym="AMC6; NEB177D; NEM2"
                     /inference="alignment:Splign:2.1.0"
     exon            6376..6687
                     /gene="NEB"
                     /gene_synonym="AMC6; NEB177D; NEM2"
                     /inference="alignment:Splign:2.1.0"
     exon            6688..6894
                     /gene="NEB"
                     /gene_synonym="AMC6; NEB177D; NEM2"
                     /inference="alignment:Splign:2.1.0"
     exon            6895..6999
                     /gene="NEB"
                     /gene_synonym="AMC6; NEB177D; NEM2"
                     /inference="alignment:Splign:2.1.0"
     exon            7000..7107
                     /gene="NEB"
                     /gene_synonym="AMC6; NEB177D; NEM2"
                     /inference="alignment:Splign:2.1.0"
     exon            7108..7419
                     /gene="NEB"
                     /gene_synonym="AMC6; NEB177D; NEM2"
                     /inference="alignment:Splign:2.1.0"
     exon            7420..7623
                     /gene="NEB"
                     /gene_synonym="AMC6; NEB177D; NEM2"
                     /inference="alignment:Splign:2.1.0"
     exon            7624..7728
                     /gene="NEB"
                     /gene_synonym="AMC6; NEB177D; NEM2"
                     /inference="alignment:Splign:2.1.0"
     exon            7729..7836
                     /gene="NEB"
                     /gene_synonym="AMC6; NEB177D; NEM2"
                     /inference="alignment:Splign:2.1.0"
     exon            7837..8148
                     /gene="NEB"
                     /gene_synonym="AMC6; NEB177D; NEM2"
                     /inference="alignment:Splign:2.1.0"
     exon            8149..8352
                     /gene="NEB"
                     /gene_synonym="AMC6; NEB177D; NEM2"
                     /inference="alignment:Splign:2.1.0"
     exon            8353..8457
                     /gene="NEB"
                     /gene_synonym="AMC6; NEB177D; NEM2"
                     /inference="alignment:Splign:2.1.0"
     exon            8458..8565
                     /gene="NEB"
                     /gene_synonym="AMC6; NEB177D; NEM2"
                     /inference="alignment:Splign:2.1.0"
     exon            8566..8877
                     /gene="NEB"
                     /gene_synonym="AMC6; NEB177D; NEM2"
                     /inference="alignment:Splign:2.1.0"
     exon            8878..9081
                     /gene="NEB"
                     /gene_synonym="AMC6; NEB177D; NEM2"
                     /inference="alignment:Splign:2.1.0"
     exon            9082..9186
                     /gene="NEB"
                     /gene_synonym="AMC6; NEB177D; NEM2"
                     /inference="alignment:Splign:2.1.0"
     exon            9187..9294
                     /gene="NEB"
                     /gene_synonym="AMC6; NEB177D; NEM2"
                     /inference="alignment:Splign:2.1.0"
     exon            9295..9606
                     /gene="NEB"
                     /gene_synonym="AMC6; NEB177D; NEM2"
                     /inference="alignment:Splign:2.1.0"
     exon            9607..9810
                     /gene="NEB"
                     /gene_synonym="AMC6; NEB177D; NEM2"
                     /inference="alignment:Splign:2.1.0"
     exon            9811..9915
                     /gene="NEB"
                     /gene_synonym="AMC6; NEB177D; NEM2"
                     /inference="alignment:Splign:2.1.0"
     exon            9916..10023
                     /gene="NEB"
                     /gene_synonym="AMC6; NEB177D; NEM2"
                     /inference="alignment:Splign:2.1.0"
     exon            10024..10335
                     /gene="NEB"
                     /gene_synonym="AMC6; NEB177D; NEM2"
                     /inference="alignment:Splign:2.1.0"
     exon            10336..10539
                     /gene="NEB"
                     /gene_synonym="AMC6; NEB177D; NEM2"
                     /inference="alignment:Splign:2.1.0"
     exon            10540..10644
                     /gene="NEB"
                     /gene_synonym="AMC6; NEB177D; NEM2"
                     /inference="alignment:Splign:2.1.0"
     exon            10645..10752
                     /gene="NEB"
                     /gene_synonym="AMC6; NEB177D; NEM2"
                     /inference="alignment:Splign:2.1.0"
     exon            10753..11064
                     /gene="NEB"
                     /gene_synonym="AMC6; NEB177D; NEM2"
                     /inference="alignment:Splign:2.1.0"
     exon            11065..11268
                     /gene="NEB"
                     /gene_synonym="AMC6; NEB177D; NEM2"
                     /inference="alignment:Splign:2.1.0"
     exon            11269..11373
                     /gene="NEB"
                     /gene_synonym="AMC6; NEB177D; NEM2"
                     /inference="alignment:Splign:2.1.0"
     exon            11374..11481
                     /gene="NEB"
                     /gene_synonym="AMC6; NEB177D; NEM2"
                     /inference="alignment:Splign:2.1.0"
     exon            11482..11793
                     /gene="NEB"
                     /gene_synonym="AMC6; NEB177D; NEM2"
                     /inference="alignment:Splign:2.1.0"
     exon            11794..11997
                     /gene="NEB"
                     /gene_synonym="AMC6; NEB177D; NEM2"
                     /inference="alignment:Splign:2.1.0"
     exon            11998..12102
                     /gene="NEB"
                     /gene_synonym="AMC6; NEB177D; NEM2"
                     /inference="alignment:Splign:2.1.0"
     exon            12103..12210
                     /gene="NEB"
                     /gene_synonym="AMC6; NEB177D; NEM2"
                     /inference="alignment:Splign:2.1.0"
     exon            12211..12522
                     /gene="NEB"
                     /gene_synonym="AMC6; NEB177D; NEM2"
                     /inference="alignment:Splign:2.1.0"
     exon            12523..12726
                     /gene="NEB"
                     /gene_synonym="AMC6; NEB177D; NEM2"
                     /inference="alignment:Splign:2.1.0"
     exon            12727..12831
                     /gene="NEB"
                     /gene_synonym="AMC6; NEB177D; NEM2"
                     /inference="alignment:Splign:2.1.0"
     exon            12832..12939
                     /gene="NEB"
                     /gene_synonym="AMC6; NEB177D; NEM2"
                     /inference="alignment:Splign:2.1.0"
     exon            12940..13251
                     /gene="NEB"
                     /gene_synonym="AMC6; NEB177D; NEM2"
                     /inference="alignment:Splign:2.1.0"
     exon            13252..13455
                     /gene="NEB"
                     /gene_synonym="AMC6; NEB177D; NEM2"
                     /inference="alignment:Splign:2.1.0"
     exon            13456..13560
                     /gene="NEB"
                     /gene_synonym="AMC6; NEB177D; NEM2"
                     /inference="alignment:Splign:2.1.0"
     exon            13561..13668
                     /gene="NEB"
                     /gene_synonym="AMC6; NEB177D; NEM2"
                     /inference="alignment:Splign:2.1.0"
     exon            13669..13980
                     /gene="NEB"
                     /gene_synonym="AMC6; NEB177D; NEM2"
                     /inference="alignment:Splign:2.1.0"
     exon            13981..14184
                     /gene="NEB"
                     /gene_synonym="AMC6; NEB177D; NEM2"
                     /inference="alignment:Splign:2.1.0"
     exon            14185..14289
                     /gene="NEB"
                     /gene_synonym="AMC6; NEB177D; NEM2"
                     /inference="alignment:Splign:2.1.0"
     exon            14290..14397
                     /gene="NEB"
                     /gene_synonym="AMC6; NEB177D; NEM2"
                     /inference="alignment:Splign:2.1.0"
     exon            14398..14709
                     /gene="NEB"
                     /gene_synonym="AMC6; NEB177D; NEM2"
                     /inference="alignment:Splign:2.1.0"
     exon            14710..14913
                     /gene="NEB"
                     /gene_synonym="AMC6; NEB177D; NEM2"
                     /inference="alignment:Splign:2.1.0"
     exon            14914..15018
                     /gene="NEB"
                     /gene_synonym="AMC6; NEB177D; NEM2"
                     /inference="alignment:Splign:2.1.0"
     exon            15019..15126
                     /gene="NEB"
                     /gene_synonym="AMC6; NEB177D; NEM2"
                     /inference="alignment:Splign:2.1.0"
     exon            15127..15438
                     /gene="NEB"
                     /gene_synonym="AMC6; NEB177D; NEM2"
                     /inference="alignment:Splign:2.1.0"
     exon            15439..15642
                     /gene="NEB"
                     /gene_synonym="AMC6; NEB177D; NEM2"
                     /inference="alignment:Splign:2.1.0"
     exon            15643..15747
                     /gene="NEB"
                     /gene_synonym="AMC6; NEB177D; NEM2"
                     /inference="alignment:Splign:2.1.0"
     exon            15748..15855
                     /gene="NEB"
                     /gene_synonym="AMC6; NEB177D; NEM2"
                     /inference="alignment:Splign:2.1.0"
     exon            15856..16167
                     /gene="NEB"
                     /gene_synonym="AMC6; NEB177D; NEM2"
                     /inference="alignment:Splign:2.1.0"
     exon            16168..16371
                     /gene="NEB"
                     /gene_synonym="AMC6; NEB177D; NEM2"
                     /inference="alignment:Splign:2.1.0"
     exon            16372..16476
                     /gene="NEB"
                     /gene_synonym="AMC6; NEB177D; NEM2"
                     /inference="alignment:Splign:2.1.0"
     exon            16477..16584
                     /gene="NEB"
                     /gene_synonym="AMC6; NEB177D; NEM2"
                     /inference="alignment:Splign:2.1.0"
     exon            16585..16896
                     /gene="NEB"
                     /gene_synonym="AMC6; NEB177D; NEM2"
                     /inference="alignment:Splign:2.1.0"
     exon            16897..17100
                     /gene="NEB"
                     /gene_synonym="AMC6; NEB177D; NEM2"
                     /inference="alignment:Splign:2.1.0"
     exon            17101..17205
                     /gene="NEB"
                     /gene_synonym="AMC6; NEB177D; NEM2"
                     /inference="alignment:Splign:2.1.0"
     exon            17206..17310
                     /gene="NEB"
                     /gene_synonym="AMC6; NEB177D; NEM2"
                     /inference="alignment:Splign:2.1.0"
     exon            17311..17622
                     /gene="NEB"
                     /gene_synonym="AMC6; NEB177D; NEM2"
                     /inference="alignment:Splign:2.1.0"
     exon            17623..17727
                     /gene="NEB"
                     /gene_synonym="AMC6; NEB177D; NEM2"
                     /inference="alignment:Splign:2.1.0"
     exon            17728..17826
                     /gene="NEB"
                     /gene_synonym="AMC6; NEB177D; NEM2"
                     /inference="alignment:Splign:2.1.0"
     exon            17827..17928
                     /gene="NEB"
                     /gene_synonym="AMC6; NEB177D; NEM2"
                     /inference="alignment:Splign:2.1.0"
     exon            17929..18036
                     /gene="NEB"
                     /gene_synonym="AMC6; NEB177D; NEM2"
                     /inference="alignment:Splign:2.1.0"
     exon            18037..18348
                     /gene="NEB"
                     /gene_synonym="AMC6; NEB177D; NEM2"
                     /inference="alignment:Splign:2.1.0"
     exon            18349..18453
                     /gene="NEB"
                     /gene_synonym="AMC6; NEB177D; NEM2"
                     /inference="alignment:Splign:2.1.0"
     exon            18454..18558
                     /gene="NEB"
                     /gene_synonym="AMC6; NEB177D; NEM2"
                     /inference="alignment:Splign:2.1.0"
     exon            18559..18663
                     /gene="NEB"
                     /gene_synonym="AMC6; NEB177D; NEM2"
                     /inference="alignment:Splign:2.1.0"
     exon            18664..18771
                     /gene="NEB"
                     /gene_synonym="AMC6; NEB177D; NEM2"
                     /inference="alignment:Splign:2.1.0"
     exon            18772..18885
                     /gene="NEB"
                     /gene_synonym="AMC6; NEB177D; NEM2"
                     /inference="alignment:Splign:2.1.0"
     exon            18886..19083
                     /gene="NEB"
                     /gene_synonym="AMC6; NEB177D; NEM2"
                     /inference="alignment:Splign:2.1.0"
     exon            19084..19188
                     /gene="NEB"
                     /gene_synonym="AMC6; NEB177D; NEM2"
                     /inference="alignment:Splign:2.1.0"
     exon            19189..19293
                     /gene="NEB"
                     /gene_synonym="AMC6; NEB177D; NEM2"
                     /inference="alignment:Splign:2.1.0"
     exon            19294..19398
                     /gene="NEB"
                     /gene_synonym="AMC6; NEB177D; NEM2"
                     /inference="alignment:Splign:2.1.0"
     exon            19399..19506
                     /gene="NEB"
                     /gene_synonym="AMC6; NEB177D; NEM2"
                     /inference="alignment:Splign:2.1.0"
     exon            19507..19620
                     /gene="NEB"
                     /gene_synonym="AMC6; NEB177D; NEM2"
                     /inference="alignment:Splign:2.1.0"
     exon            19621..19818
                     /gene="NEB"
                     /gene_synonym="AMC6; NEB177D; NEM2"
                     /inference="alignment:Splign:2.1.0"
     exon            19819..19923
                     /gene="NEB"
                     /gene_synonym="AMC6; NEB177D; NEM2"
                     /inference="alignment:Splign:2.1.0"
     exon            19924..20028
                     /gene="NEB"
                     /gene_synonym="AMC6; NEB177D; NEM2"
                     /inference="alignment:Splign:2.1.0"
     exon            20029..20136
                     /gene="NEB"
                     /gene_synonym="AMC6; NEB177D; NEM2"
                     /inference="alignment:Splign:2.1.0"
     exon            20137..20241
                     /gene="NEB"
                     /gene_synonym="AMC6; NEB177D; NEM2"
                     /inference="alignment:Splign:2.1.0"
     exon            20242..20349
                     /gene="NEB"
                     /gene_synonym="AMC6; NEB177D; NEM2"
                     /inference="alignment:Splign:2.1.0"
     exon            20350..20454
                     /gene="NEB"
                     /gene_synonym="AMC6; NEB177D; NEM2"
                     /inference="alignment:Splign:2.1.0"
     exon            20455..20559
                     /gene="NEB"
                     /gene_synonym="AMC6; NEB177D; NEM2"
                     /inference="alignment:Splign:2.1.0"
     exon            20560..20658
                     /gene="NEB"
                     /gene_synonym="AMC6; NEB177D; NEM2"
                     /inference="alignment:Splign:2.1.0"
     exon            20659..20769
                     /gene="NEB"
                     /gene_synonym="AMC6; NEB177D; NEM2"
                     /inference="alignment:Splign:2.1.0"
     exon            20770..20874
                     /gene="NEB"
                     /gene_synonym="AMC6; NEB177D; NEM2"
                     /inference="alignment:Splign:2.1.0"
     exon            20875..20979
                     /gene="NEB"
                     /gene_synonym="AMC6; NEB177D; NEM2"
                     /inference="alignment:Splign:2.1.0"
     exon            20980..21084
                     /gene="NEB"
                     /gene_synonym="AMC6; NEB177D; NEM2"
                     /inference="alignment:Splign:2.1.0"
     exon            21085..21189
                     /gene="NEB"
                     /gene_synonym="AMC6; NEB177D; NEM2"
                     /inference="alignment:Splign:2.1.0"
     exon            21190..21294
                     /gene="NEB"
                     /gene_synonym="AMC6; NEB177D; NEM2"
                     /inference="alignment:Splign:2.1.0"
     exon            21295..21399
                     /gene="NEB"
                     /gene_synonym="AMC6; NEB177D; NEM2"
                     /inference="alignment:Splign:2.1.0"
     exon            21400..21504
                     /gene="NEB"
                     /gene_synonym="AMC6; NEB177D; NEM2"
                     /inference="alignment:Splign:2.1.0"
     exon            21505..21609
                     /gene="NEB"
                     /gene_synonym="AMC6; NEB177D; NEM2"
                     /inference="alignment:Splign:2.1.0"
     exon            21610..21714
                     /gene="NEB"
                     /gene_synonym="AMC6; NEB177D; NEM2"
                     /inference="alignment:Splign:2.1.0"
     exon            21715..21822
                     /gene="NEB"
                     /gene_synonym="AMC6; NEB177D; NEM2"
                     /inference="alignment:Splign:2.1.0"
     exon            21823..21927
                     /gene="NEB"
                     /gene_synonym="AMC6; NEB177D; NEM2"
                     /inference="alignment:Splign:2.1.0"
     exon            21928..22032
                     /gene="NEB"
                     /gene_synonym="AMC6; NEB177D; NEM2"
                     /inference="alignment:Splign:2.1.0"
     exon            22033..22137
                     /gene="NEB"
                     /gene_synonym="AMC6; NEB177D; NEM2"
                     /inference="alignment:Splign:2.1.0"
     exon            22138..22242
                     /gene="NEB"
                     /gene_synonym="AMC6; NEB177D; NEM2"
                     /inference="alignment:Splign:2.1.0"
     exon            22243..22353
                     /gene="NEB"
                     /gene_synonym="AMC6; NEB177D; NEM2"
                     /inference="alignment:Splign:2.1.0"
     exon            22354..22464
                     /gene="NEB"
                     /gene_synonym="AMC6; NEB177D; NEM2"
                     /inference="alignment:Splign:2.1.0"
     exon            22465..22566
                     /gene="NEB"
                     /gene_synonym="AMC6; NEB177D; NEM2"
                     /inference="alignment:Splign:2.1.0"
     exon            22567..22671
                     /gene="NEB"
                     /gene_synonym="AMC6; NEB177D; NEM2"
                     /inference="alignment:Splign:2.1.0"
     exon            22672..22782
                     /gene="NEB"
                     /gene_synonym="AMC6; NEB177D; NEM2"
                     /inference="alignment:Splign:2.1.0"
     exon            22783..22887
                     /gene="NEB"
                     /gene_synonym="AMC6; NEB177D; NEM2"
                     /inference="alignment:Splign:2.1.0"
     exon            22888..22992
                     /gene="NEB"
                     /gene_synonym="AMC6; NEB177D; NEM2"
                     /inference="alignment:Splign:2.1.0"
     exon            22993..23097
                     /gene="NEB"
                     /gene_synonym="AMC6; NEB177D; NEM2"
                     /inference="alignment:Splign:2.1.0"
     exon            23098..23208
                     /gene="NEB"
                     /gene_synonym="AMC6; NEB177D; NEM2"
                     /inference="alignment:Splign:2.1.0"
     exon            23209..23319
                     /gene="NEB"
                     /gene_synonym="AMC6; NEB177D; NEM2"
                     /inference="alignment:Splign:2.1.0"
     exon            23320..23433
                     /gene="NEB"
                     /gene_synonym="AMC6; NEB177D; NEM2"
                     /inference="alignment:Splign:2.1.0"
     exon            23434..23538
                     /gene="NEB"
                     /gene_synonym="AMC6; NEB177D; NEM2"
                     /inference="alignment:Splign:2.1.0"
     exon            23539..23643
                     /gene="NEB"
                     /gene_synonym="AMC6; NEB177D; NEM2"
                     /inference="alignment:Splign:2.1.0"
     exon            23644..23748
                     /gene="NEB"
                     /gene_synonym="AMC6; NEB177D; NEM2"
                     /inference="alignment:Splign:2.1.0"
     exon            23749..23841
                     /gene="NEB"
                     /gene_synonym="AMC6; NEB177D; NEM2"
                     /inference="alignment:Splign:2.1.0"
     exon            23842..23934
                     /gene="NEB"
                     /gene_synonym="AMC6; NEB177D; NEM2"
                     /inference="alignment:Splign:2.1.0"
     exon            23935..24027
                     /gene="NEB"
                     /gene_synonym="AMC6; NEB177D; NEM2"
                     /inference="alignment:Splign:2.1.0"
     exon            24028..24120
                     /gene="NEB"
                     /gene_synonym="AMC6; NEB177D; NEM2"
                     /inference="alignment:Splign:2.1.0"
     exon            24121..24213
                     /gene="NEB"
                     /gene_synonym="AMC6; NEB177D; NEM2"
                     /inference="alignment:Splign:2.1.0"
     exon            24214..24306
                     /gene="NEB"
                     /gene_synonym="AMC6; NEB177D; NEM2"
                     /inference="alignment:Splign:2.1.0"
     exon            24307..24399
                     /gene="NEB"
                     /gene_synonym="AMC6; NEB177D; NEM2"
                     /inference="alignment:Splign:2.1.0"
     exon            24400..24492
                     /gene="NEB"
                     /gene_synonym="AMC6; NEB177D; NEM2"
                     /inference="alignment:Splign:2.1.0"
     exon            24493..24585
                     /gene="NEB"
                     /gene_synonym="AMC6; NEB177D; NEM2"
                     /inference="alignment:Splign:2.1.0"
     exon            24586..24678
                     /gene="NEB"
                     /gene_synonym="AMC6; NEB177D; NEM2"
                     /inference="alignment:Splign:2.1.0"
     exon            24679..24771
                     /gene="NEB"
                     /gene_synonym="AMC6; NEB177D; NEM2"
                     /inference="alignment:Splign:2.1.0"
     exon            24772..24864
                     /gene="NEB"
                     /gene_synonym="AMC6; NEB177D; NEM2"
                     /inference="alignment:Splign:2.1.0"
     exon            24865..24957
                     /gene="NEB"
                     /gene_synonym="AMC6; NEB177D; NEM2"
                     /inference="alignment:Splign:2.1.0"
     exon            24958..25065
                     /gene="NEB"
                     /gene_synonym="AMC6; NEB177D; NEM2"
                     /inference="alignment:Splign:2.1.0"
     exon            25066..25249
                     /gene="NEB"
                     /gene_synonym="AMC6; NEB177D; NEM2"
                     /inference="alignment:Splign:2.1.0"
     exon            25250..25342
                     /gene="NEB"
                     /gene_synonym="AMC6; NEB177D; NEM2"
                     /inference="alignment:Splign:2.1.0"
     exon            25343..25489
                     /gene="NEB"
                     /gene_synonym="AMC6; NEB177D; NEM2"
                     /inference="alignment:Splign:2.1.0"
     exon            25490..25596
                     /gene="NEB"
                     /gene_synonym="AMC6; NEB177D; NEM2"
                     /inference="alignment:Splign:2.1.0"
     exon            25597..26191
                     /gene="NEB"
                     /gene_synonym="AMC6; NEB177D; NEM2"
                     /inference="alignment:Splign:2.1.0"
     regulatory      26170..26175
                     /regulatory_class="polyA_signal_sequence"
                     /gene="NEB"
                     /gene_synonym="AMC6; NEB177D; NEM2"
                     /note="hexamer: AATAAA"
     polyA_site      26191
                     /gene="NEB"
                     /gene_synonym="AMC6; NEB177D; NEM2"
                     /note="major polyA site"
ORIGIN      
        1 tggcttttgc ctggggttct caggagggga gagttgggag aggctttgct gctgaggaaa
       61 tttatttggt agattgaagg tttgaacgag agctacagaa acgaaagaaa aagtctgtat
      121 aagccaatgg tgttcgggaa gaaaataacc ccattgcctt gagtttgtag gtgccactac
      181 tactctggaa aaatggcaga tgacgaagac tatgaggagg tggtggagta ctacacagaa
      241 gaagtggttt acgaagaggt gccgggagag acaataacaa aaatttatga gactacgaca
      301 acaaggacat ctgactatga gcaatcagaa acttccaaac cagctctggc acagccagca
      361 ctggcacagc cagcatcagc aaagccggtg gagaggagga aggtcatccg gaagaaagtg
      421 gatccttcaa agttcatgac cccctacatt gcacacagtc agaaaatgca ggatcttttt
      481 agcccaaata aatacaagga gaagtttgag aaaacaaaag gacagccata cgccagcaca
      541 acagatactc cagaacttcg cagaatcaaa aaagtacaag atcaactcag tgaggttaag
      601 tatcgaatgg atggtgatgt tgctaagact atatgtcacg tagatgaaaa agcaaaggat
      661 attgaacatg caaagaaagt gtcgcagcaa gtcagtaagg ttttatacaa gcagaactgg
      721 gaagacacca aggataagta cctgcttcct cctgatgccc ctgaacttgt ccaggccgtt
      781 aagaacaccg ccatgttcag caagaaactg tacactgaag actgggaagc agacaaaagt
      841 ttgttttacc cctataatga tagcccggaa ctgaggagag ttgcccaggc ccagaaagct
      901 ctcagtgatg ttgcctacaa aaaaggtctc gctgaacagc aagctcaatt cacgcctctg
      961 gctgatcctc cagatataga atttgccaag aaagtaacca atcaagtgag caagcaaaaa
     1021 tacaaagaag actatgaaaa taaaatcaaa ggcaaatgga gtgagacacc ttgctttgaa
     1081 gttgcaaatg ccagaatgaa tgctgataac attagcacaa ggaaatacca ggaagatttt
     1141 gaaaacatga aagaccagat ctacttcatg cagaccgaaa caccagagta taaaatgaat
     1201 aaaaaagctg gtgtggcagc tagcaaggta aaatacaaag aagactatga aaagaataaa
     1261 ggaaaagcag attataatgt gcttcctgct tcagagaacc cacagcttag gcagctgaag
     1321 gcagcaggag atgccctaag tgacaaacta tacaaggaaa actatgaaaa gacaaaagca
     1381 aagagcataa attactgcga gacccccaaa ttcaagctcg atactgttct gcagaacttc
     1441 agtagtgata aaaaatataa agattcctac ttaaaagata ttttgggaca ttatgtaggc
     1501 agcttcgagg atccatacca ttcacactgc atgaaagtca cagctcaaaa cagtgataaa
     1561 aactacaaag cagaatacga agaagacaga ggcaaaggct tcttccctca gaccataact
     1621 caagaatatg aagcaattaa gaaactagat cagtgtaaag accacaccta caaagtccat
     1681 ccagataaga caaaattcac ccaagttaca gactctcctg ttctgctaca agcccaagtc
     1741 aattccaaac aactgagtga cttaaattac aaagcaaaac atgaaagtga aaagttcaag
     1801 tgccatatcc cccctgatac tcctgctttt atccagcaca aagtcaatgc ctataacttg
     1861 agtgataatc tttataagca agactgggag aagagcaaag ccaaaaagtt tgacattaaa
     1921 gtggatgcca ttcccctgct ggcagccaaa gccaacacca agaacaccag cgatgtgatg
     1981 tacaagaaag actatgaaaa aaacaaaggg aaaatgattg gagtcctcag cattaatgac
     2041 gatcccaaga tgctgcactc cttgaaggtg gccaaaaacc agagtgatag attatacaag
     2101 gaaaactatg agaagacaaa ggcaaagagt atgaattact gtgagacccc aaaatatcaa
     2161 cttgatactc agctgaagaa cttcagtgag gctagatata aagacttata tgtaaaggat
     2221 gttttgggac attatgtagg cagcatggag gacccatatc acacacactg catgaaagtt
     2281 gcagctcaaa acagtgataa aagttacaaa gcagaatatg aagaagataa aggaaaatgc
     2341 tatttccctc agacaataac acaagaatat gaagcaatca agaagctgga ccagtgtaaa
     2401 gatcatacct acaaagttca tccagataag accaaattca cggcagtcac tgattctcct
     2461 gtactgttgc aagcccagct caacacgaaa cagcttagtg atctgaatta caaagcaaaa
     2521 catgaaggtg agaagttcaa gtgccatata ccagcagatg ctccacagtt tatccaacac
     2581 agagtcaatg cctataatct gagtgataat gtttataagc aagactggga gaagagcaaa
     2641 gccaagaagt ttgacattaa agtggacgcc attcccctgt tggcagccaa agccaacacc
     2701 aagaacacca gcgatgtgat gtacaagaaa gactatgaaa agagcaaagg gaaaatgatt
     2761 ggagccctca gcattaatga cgatccaaag atgctgcact ccttgaagac agccaaaaac
     2821 cagagtgatc gcgaatatcg aaaagattat gaaaagtcaa aaactatcta cacggcacct
     2881 cttgatatgc tccaagtcac tcaagctaag aaatctcagg caattgccag cgacgttgat
     2941 tataagcaca tcttacacag ttacagctac ccccctgata gcatcaatgt ggaccttgcc
     3001 aagaaggcat atgcgctgca gagcgatgtt gaatacaaag ctgactacaa tagctggatg
     3061 aaaggttgtg gctgggtgcc ttttgggtcc ttagaaatgg aaaaggcaaa gcgagcttca
     3121 gacatcctca atgagaaaaa atatcgccaa catccagaca ccctcaagtt tacctcgatt
     3181 gaagatgctc caattacagt acagtctaaa attaaccagg cccagaggag tgatatcgct
     3241 tacaaagcca aaggagagga aattattcac aaatacaacc tgccaccaga cctgccccag
     3301 ttcatccagg ctaaagttaa tgcctacaat atcagtgaga atatgtacaa agcagacttg
     3361 aaagacttga gcaagaaggg atatgacctg agaactgatg cgattcccat cagagctgcc
     3421 aaagctgcca ggcaggcggc gagtgacgtt cagtacaaaa aagactatga aaaggctaaa
     3481 gggaaaatgg ttggcttcca aagtcttcaa gatgacccta aactggttca ttatatgaac
     3541 gtggccaaga tacaatcaga tcgggagtat aaaaaagact atgagaagac aaagtccaaa
     3601 tacaacacgc cccatgatat gttcaatgtc gtggcggcta agaaagccca ggatgtggtc
     3661 agcaatgtca actataagca ttctctccat cattacacct acttgcctga cgccatggac
     3721 ctggagctgt ctaagaacat gatgcagata cagagtgata acgtctacaa ggaagactac
     3781 aacaactgga tgaaaggcat tggctggatt cctattggca gtctcgacgt cgaaaaagtt
     3841 aaaaaggccg gtgatgctct gaatgaaaag aagtacaggc aacatccaga caccctcaaa
     3901 tttaccagca ttgtggactc cccagttatg gtccaggcaa aacagaacac gaagcaagtc
     3961 agtgatatct tatacaaggc taaaggagaa gatgtgaaac ataaatacac catgagtcct
     4021 gatcttcctc agtttctcca ggccaagtgc aatgcttaca atataagtga cgtctgttat
     4081 aaacgggatt ggtatgactt aatagccaag ggcaacaatg tgctgggcga tgctattccc
     4141 atcactgcag ccaaggcatc gagaaacatt gccagtgatt ataaatacaa ggaagcttat
     4201 gagaagtcaa agggaaagca tgtgggtttc agaagcctcc aggatgatcc caagctggtc
     4261 cactatatga atgtggcaaa gctgcagtct gatcgtgaat acaagaagaa ctatgagaac
     4321 accaaaacca gctaccatac ccctggggac atggttagca tcacagctgc aaagatggcc
     4381 caggatgtcg ctaccaatgt caactacaaa cagccattgc atcattacac atacctacct
     4441 gacgccatga gtcttgagca tacgaggaat gtcaatcaaa ttcagagtga taatgtgtat
     4501 aaagacgagt ataacagctt cttgaagggc atcggatgga tccctattgg ttccctggag
     4561 gtggagaagg tcaagaaagc aggcgatgca ttaaatgaga ggaagtatcg acagcaccca
     4621 gataccgtca agttcacaag tgtgcctgat tccatgggca tggtgttggc tcagcataac
     4681 acaaagcagc taagtgattt gaactacaag gtagagggag agaaactgaa gcacaagtat
     4741 actattgacc ctgaattgcc tcagtttatt caagccaaag tcaacgccct caacatgagt
     4801 gatgctcatt ataaagcaga ttggaagaaa accattgcca agggctatga tttgagacca
     4861 gatgccatcc caattgttgc tgcaaaaagt tcaaggaata ttgctagtga ttgcaaatat
     4921 aaggaggcct acgagaaagc caaaggcaag caagttggat ttctcagtct tcaggatgat
     4981 cctaaactgg ttcactacat gaatgtggcc aaaatccagt ctgatcgtga gtacaaaaag
     5041 ggctatgaag ccagcaagac caagtaccac acacctctgg atatggtcag tgtgacagct
     5101 gcaaagaaat ctcaggaggt tgccaccaac gccaactaca gacagtcata ccaccactac
     5161 actctcctgc ccgatgcctt gaatgtggag cactccagga atgccatgca gattcagagt
     5221 gataatctgt acaaatctga cttcaccaat tggatgaaag ggatcggctg ggtgcccata
     5281 gagtccctgg aggtggagaa ggcaaagaaa gcaggagaga ttcttagtga gaagaagtat
     5341 cgccagcacc ccgagaagct gaagttcact tacgccatgg acacaatgga acaggcactt
     5401 aacaagagta acaaactgaa catggacaag aggctctaca ctgaaaaatg gaacaaggac
     5461 aagaccacca ttcatgtcat gcctgacaca ccggatattt tactctccag agtaaaccaa
     5521 atcaccatga gtgataaact gtacaaagct ggctgggaag aggaaaagaa gaaaggatat
     5581 gacctgaggc ctgatgccat tgcaataaag gctgcaagag cctctagaga cattgccagt
     5641 gattacaaat acaagaaagc ctatgaacaa gccaaaggga aacacattgg cttccggagc
     5701 ctggaagatg accccaagct ggtgcacttc atgcaagtgg ccaagatgca gtcagaccgg
     5761 gaatacaaga agggatatga gaaatccaag acctccttcc acaccccggt ggacatgctc
     5821 agtgtggtgg cagccaagaa gtctcaggaa gtggccacca atgccaacta caggaacgtg
     5881 atccatacct acaacatgct tcctgatgcc atgagctttg aattggccaa aaatatgatg
     5941 cagattcaaa gtgataatca gtacaaggct gactatgctg acttcatgaa gggcattgga
     6001 tggctccctc tgggctccct ggaagcagag aaaaacaaga aagccatgga gattattagt
     6061 gaaaagaagt accgccagca cccagacact ttgaagtatt ccacactcat ggactcgatg
     6121 aacatggttt tggcccagaa taatgcaaaa attatgaacg aacatctcta caaacaagca
     6181 tgggaggctg acaaaaccaa agtccacatc atgcctgata tcccccagat tattttggca
     6241 aaggcaaatg caattaatat gagtgataaa ctctacaaac tttccttgga agagtctaaa
     6301 aagaaaggct atgatctcag acctgatgca attcctatca aagctgccaa ggcttccaga
     6361 gatattgcaa gtgattataa atacaagtac aattatgaaa aagggaaggg gaaaatggtt
     6421 ggtttccgca gtctcgagga tgatcccaaa ttagtccatt ccatgcaagt ggctaagatg
     6481 caatctgatc gggagtacaa gaaaaactat gagaacacaa agaccagcta ccacacccct
     6541 gccgacatgc tcagtgtcac ggctgcaaag gatgcccaag ccaacatcac caacactaac
     6601 tacaagcacc tgattcacaa gtacatcctc cttccagatg caatgaacat tgagctgacc
     6661 aggaatatga atcgcataca gagtgataat gaatataagc aagattacaa tgaatggtac
     6721 aaagggcttg gctggagtcc agcaggttct ctggaagtgg agaaggccaa gaaagcaact
     6781 gaatatgcca gtgatcagaa ataccgccag cacccgagca acttccagtt taagaagctg
     6841 actgattcca tggacatggt gcttgccaag cagaatgcac ataccatgaa caagcattta
     6901 tacaccattg attggaataa agataagacc aagattcatg tgatgcctga tacaccagat
     6961 attttacaag ccaagcagaa tcaaacactg tatagtcaga aactctataa acttggatgg
     7021 gaagaagctt tgaagaaagg ctatgatctc ccagttgatg caatttctgt acagctagct
     7081 aaagcttcaa gagacattgc tagtgattat aaatacaaac aaggctaccg aaagcaactt
     7141 ggccaccatg ttggattccg gagtctgcaa gatgacccaa aacttgtgtt gtccatgaat
     7201 gtagccaaaa tgcagagtga aagagaatac aagaaggact ttgagaagtg gaaaactaag
     7261 ttctccagcc cagtggacat gttgggagtg gtactggcca agaagtgtca ggagttggtt
     7321 agtgacgtgg actacaagaa ctacctgcat cagtggacat gtctgcctga tcagaacgat
     7381 gttgtgcaag ctaagaaagt ttatgaactg caaagtgaga atctatataa atctgacctt
     7441 gagtggctga gaggcatagg atggagtccc ttgggttctt tagaggcaga aaagaacaag
     7501 cgggcttcgg aaatcatcag tgagaagaaa tatcgtcagc ctccagacag aaacaagttc
     7561 accagcattc ctgatgccat ggatatagtt ctggcaaaga caaatgccaa aaataggagt
     7621 gatagacttt atagagaagc ttgggacaaa gacaagactc agatccacat catgcctgat
     7681 acacctgaca ttgttctggc taaagcaaac ttaatcaaca caagtgataa actctaccga
     7741 atgggttatg aggagctgaa gagaaaaggt tacgatcttc ctgttgatgc cataccaatc
     7801 aaagcagcaa aagcctcccg ggaaattgcc agtgaataca agtacaagga aggctttcgc
     7861 aagcagctcg gccaccacat tggtgcccgg aacattgaag atgaccccaa gatgatgtgg
     7921 tccatgcatg tggccaagat ccagagtgac agggagtaca agaaggactt tgagaagtgg
     7981 aagaccaagt tcagcagccc agtggacatg ctgggggtgg tgttggccaa gaagtgccag
     8041 accttagtca gcgacgtgga ctacaagaac tacctgcacc agtggacatg cctgcccgac
     8101 cagagcgatg tcatccatgc tcggcaggcc tatgacctcc agagcgataa tttgtacaag
     8161 tcagaccttc agtggctaaa aggcattggc tggatgacta gtggttctct cgaggatgag
     8221 aaaaataaac gagccaccca gattttgagt gaccatgttt accgtcagca cccagatcaa
     8281 tttaagtttt ccagccttat ggattccata ccaatggttt tggcaaaaaa caatgctatt
     8341 accatgaatc atcgcctcta tacagaagct tgggataaag ataaaaccac tgtccacatt
     8401 atgccagata cccctgaagt tttattagct aaacaaaaca aagtaaatta cagtgagaaa
     8461 ttgtataagc ttggcctaga agaagccaag aggaaaggtt atgacatgcg ggtagatgcc
     8521 attcctatca aggcagccaa ggcctccaga gatattgcaa gtgaattcaa gtacaaagaa
     8581 ggctatcgta agcagctcgg ccaccacatt ggtgcccgag ctatacgtga tgaccccaag
     8641 atgatgtggt ccatgcacgt ggccaagatc cagagtgaca gggagtacaa gaaggacttt
     8701 gagaagtgga agaccaagtt cagcagccca gtggacatgc tgggggtggt gctggccaag
     8761 aagtgccaga ccttagtcag cgatgtggac tacaagaact acctgcacca gtggacatgc
     8821 ctgcccgacc agagcgacgt catccatgct cggcaggcct atgacctcca gagcgataat
     8881 atgtacaagt ctgatctcca gtggatgaga ggcattggct gggtgtccat tggctctttg
     8941 gatgtggaaa aatgcaaaag ggcaactgaa attttgagtg ataaaatcta tcgccagcct
     9001 ccagacagat tcaaatttac cagtgtgact gactctctgg aacaagtgtt ggccaaaaat
     9061 aatgccatca ctatgaacaa gcgtttatac acagaagcct gggacaaaga caagactcag
     9121 atccacataa tgccagacac accagaaatt atgttggcaa gaatgaacaa aatcaactac
     9181 agtgagagtc tgtacaaact tgctaatgaa gaagcaaaga agaaaggcta tgacttgcga
     9241 agcgacgcca tccccatcgt ggcggccaag gcctccaggg acatcatcag tgactacaaa
     9301 tataaagatg gttactgcaa gcaacttggc caccatattg gagcccggaa cattgaagat
     9361 gaccccaaga tgatgtggtc catgcacgta gccaagatcc agagtgacag ggagtacaaa
     9421 aaggactttg agaagtggaa gaccaagttc agcagcccag tggacatgct gggggtggtg
     9481 ctggccaaga agtgccagac cttagtcagt gacgtggact ataagaacta cctgcacgag
     9541 tggacatgcc tgcctgacca gagcgatgtc atccatgctc ggcaggccta tgacctccag
     9601 agtgacaata tttacaagtc agatctccag tggctgagag gcattggctg ggtccccatt
     9661 gggtctatgg atgtggtcaa gtgcaagaga gctaccgaaa tactgagtga taacatctac
     9721 cgccagcctc cggacaagct gaaatttacc agtgtgactg attctctaga gcaggtgctg
     9781 gccaagaaca atgctctcaa catgaataag cgtttataca cagaggcctg ggacaaagac
     9841 aagactcaaa ttcacataat gcctgataca ccagagatta tgttggcaag gcagaacaaa
     9901 atcaactaca gtgagactct atacaaactt gccaatgaag aagcaaaaaa gaaaggctac
     9961 gacttgcgaa gtgacgccat ccccatcgtg gctgccaagg cctccaggga cgttatcagt
    10021 gattacaaat acaaagatgg ttaccgcaag cagctcggcc accacattgg agcccggaac
    10081 attgaagatg accccaagat gatgtggtcc atgcatgtgg ccaagatcca gagtgacagg
    10141 gagtataaga aggactttga gaagtggaag accaagttca gcagcccagt ggacatgctg
    10201 ggagtggtgt tagccaagaa gtgccagacc ttagtcagcg atgtggacta caagaactac
    10261 ctgcacgagt ggacgtgcct gcccgaccag aatgatgtca tccatgctcg gcaggcctat
    10321 gacctccaga gcgataacat ttacaaatct gatctccagt ggctgagagg cattggctgg
    10381 gtccccattg ggtctatgga tgtggtcaag tgcaagagag ctgctgaaat actgagtgat
    10441 aacatctacc gccagcctcc ggacaagctg aaatttacca gtgtgactga ctctctagag
    10501 caggtgctgg ccaagaacaa tgctctcaat atgaacaagc gcttatacac agaagcctgg
    10561 gacaaagaca agacccaagt ccatattatg cctgatacac ctgaaatcat gttggcaaga
    10621 caaaataaaa taaattatag tgagagcctc tatcgtcagg ccatggaaga agccaagaaa
    10681 gaaggctatg acttgagaag tgatgccatt cccattgtgg ctgccaaggc ctctcgggat
    10741 attgccagtg attacaaata caaagaagca tatcgtaaac agttgggtca ccacattggc
    10801 gcccgagcag tacacgatga ccccaagata atgtggtccc tccacattgc caaagtgcag
    10861 agtgaccgtg agtacaagaa agattttgag aaatacaaga caaggtacag cagcccagtg
    10921 gacatgcttg gtatcgtttt ggccaagaag tgtcagacct tggtcagcga tgtggactat
    10981 aaacatcctc tgcatgaatg gatctgcctg cccgaccaga atgacatcat tcatgcacgg
    11041 aaagcctatg acctccagag tgacaatttg tataagtcag accttgaatg gatgaaaggc
    11101 attggctggg ttccgattga ttccttggaa gttgttaggg ccaagagagc tggagaatta
    11161 cttagtgata ctatctaccg tcagcgtcca gaaacgctga aatttaccag tataacggac
    11221 actccggagc aggtgctggc aaaaaacaat gctttaaaca tgaataagcg cttatatact
    11281 gaagcctggg acaatgacaa gaaaactatt catgtcatgc ctgatacacc agaaatcatg
    11341 ttagccaaac tcaaccgaat aaactacagt gataaactct ataaacttgc tttggaagag
    11401 tccaagaagg aaggctatga cttgcgtctg gatgccattc caatccaagc agccaaggct
    11461 tcaagagata ttgctagtga ttacaagtac aaggaaggct accgcaaaca gcttggccac
    11521 catattgggg cccggaacat taaggatgac ccgaagatga tgtggtccat ccatgtggcc
    11581 aagatccaga gtgacaggga gtacaagaag gagtttgaga agtggaagac caagttcagc
    11641 agcccagtgg acatgctggg ggtggtgctg gccaagaagt gtcagatcct tgtaagcgac
    11701 atagactaca agcatcccct gcatgaatgg acctgcctgc ctgatcagaa tgacgtcatt
    11761 caggctcgga aggcctatga cctgcagagt gatgctattt acaaatctga tcttgagtgg
    11821 ctgagaggca taggatgggt tcccattggc tctgtagagg tcgagaaagt gaagagagct
    11881 ggagaaatcc tgagtgacag gaagtatcgc cagcctgcag accagctcaa attcacatgc
    11941 attaccgaca ctccggaaat tgtcctagca aagaataatg ccctgacaat gagcaagcat
    12001 ttatacacag aagcttggga tgctgacaaa acctccatcc acgtgatgcc agacacccca
    12061 gatatcctgc tggccaagag taattctgcc aatatcagcc aaaaacttta caccaaggga
    12121 tgggatgaat caaagatgaa ggactatgat ctgagagcag atgctatttc catcaaaagt
    12181 gccaaggcct ccagggacat cgccagtgac tacaaataca aggaagccta tgagaaacag
    12241 aaaggccacc acattggagc ccagagcatt gaagatgatc ccaagattat gtgtgccata
    12301 catgcaggaa aaattcaaag tgaaagggag tacaagaagg aattccaaaa gtggaaaacc
    12361 aagttctcta gcccagtgga catgttaagc atcttgctgg ccaagaaatg tcagactttg
    12421 gtcactgaca ttgattatcg caattacctg catgaatgga catgcatgcc ggatcaaaac
    12481 gacattatcc aagcaaaaaa ggcctatgac ctgcagagtg atagtgtgta taaggcagac
    12541 ctggagtggc tgcgtggcat cggctggatg ccagaaggct cagtggaaat gaacagagtg
    12601 aaggttgctc aagacctcgt gaatgaaaga ctctatagga cacgtccaga agctttgtca
    12661 ttcaccagca ttgtcgacac tccagaagtt gtcttggcaa aagccaattc tctgcaaata
    12721 agtgagaaac tgtatcagga agcctggaat aaagataaaa gcaacatcac cattccttct
    12781 gatactccgg agatgctgca ggcccacatc aatgccttgc aaatcagcaa taaactctac
    12841 caaaaagact ggaatgacgc caagcagaaa ggctatgaca taagggcaga tgccattgaa
    12901 atcaagcacg ccaaggcctc cagagaaatt gccagtgagt acaaatacaa agaaggttac
    12961 cgtaagcaac tgggccacca catgggtttc cgcaccctac aagatgaccc caagtcagta
    13021 tgggctatac atgctgccaa gatccagagt gacagagaat ataagaaagc ttatgagaag
    13081 tctaaaggaa ttcacaacac accgttggac atgatgtcaa ttgttcaagc caagaaatgc
    13141 caggtcctgg ttagcgacat tgattatcgc aattatctgc accagtggac gtgtctgcca
    13201 gatcagaacg atgtgatcca ggccaagaaa gcctacgacc tgcagagcga taacttgtac
    13261 aagtcagacc tggaatggct gaagggtatt ggatggctgc cagagggttc tgtggaagtg
    13321 atgagagtga agaatgccca gaatctcttg aatgaaaggc tgtatcgtat aaagcctgag
    13381 gccctcaaat tcaccagcat tgttgacacc ccggaagtaa tccaggcaaa gatcaatgct
    13441 gtacagatca gtgagccatt gtatcgcgat gcctgggaga aagagaaggc taatgtgaac
    13501 gtgccagctg acactcccct gatgctgcaa tccaaaatca atgccctgca gatcagcaat
    13561 aaacgctatc agcaagcttg ggaagatgtc aagatgactg gttatgacct gcgagcagat
    13621 gccattggga tccagcatgc caaggcttcc agggatattg ccagtgacta tctgtacaaa
    13681 actgcttatg agaaacagaa aggccattac attggctgtc gcagcgccaa ggaagaccct
    13741 aaactggttt gggcagcaaa tgtgttgaag atgcagaatg acaggctgta caaaaaggcc
    13801 tacaacgacc acaaagccaa gatctccatc cctgtggaca tggtgtccat cagcgctgcc
    13861 aaagaaggtc aggcactggc aagtgatgtg gactatcgcc attacctgca ccactggtct
    13921 tgctttcccg accagaatga tgtgatccaa gccaggaaag cctacgacct acagagcgac
    13981 agtgtgtata aggcagacct ggagtggctg cgtggcatcg gctggatgcc agaaggctca
    14041 gtggaaatga acagagtgaa ggttgctcaa gacctcgtga atgaaagact ctataggaca
    14101 cgtccagaag ctttgtcatt caccagcatt gtcgacactc cagaagttgt cttggcaaaa
    14161 gccaattctc tgcaaataag tgagaaactg tatcaggaag cctggaataa agataaaagc
    14221 aacatcacca ttccttctga tactccggag atgctgcagg cccacatcaa tgccttgcaa
    14281 atcagcaata aactctacca aaaagactgg aatgacacca agcagaaagg ctatgacata
    14341 agggcagatg ccattgaaat caagcacgcc aaggcctcca gagaaattgc cagtgagtac
    14401 aaatacaaag aaggttaccg taagcaactg ggccaccaca tgggtttccg caccctacaa
    14461 gatgacccca agtcagtatg ggctatacat gctgccaaga tccagagtga cagagaatat
    14521 aagaaagctt atgagaagtc taaaggaatt cacaacacac cgttggacat gatgtcaatt
    14581 gttcaagcca agaaatgcca ggtcctggtt agcgacattg attatcgcaa ttatctgcac
    14641 cagtggacgt gtctgccaga tcagaacgat gtgatccagg ccaagaaagc ctacgacctg
    14701 cagagcgata acttgtacaa gtcagacctg gaatggctga agggtattgg atggttgcca
    14761 gagggttctg tggaagtgat gagagtgaag aatgcccaga atctcttgaa tgaaaggctg
    14821 tatcgtataa agcctgaggc cctcaaattc accagcattg ttgacacccc ggaagtaatc
    14881 caggcaaaga tcaatgctgt acagatcagt gagccattgt atcgcaatgc ctgggagaaa
    14941 gagaaggcta atgtgaacgt gccagctgac actcccctga tgctgcaatc caaaatcaat
    15001 gctctgcaga tcagcaataa acgctatcag caagcttggg aagatgtcaa gatgactggt
    15061 tatgacctgc gagcagatgc cattgggatc cagcatgcca aggcttccag ggatattgcc
    15121 agtgattatc tgtacaaaac tgcttatgag aaacagaaag gccattacat tggctgtcgc
    15181 agcgccaagg aagaccctaa actggtttgg gcagcaaatg tgttgaagat gcagaatgac
    15241 aggctgtaca aaaaggccta caacgaccac aaagccaaga tctccatccc tgtggacatg
    15301 gtgtccatca gcgctgccaa agaaggtcag gcactggcaa gtgatgtgga ctatcgccat
    15361 tacctgcacc actggtcttg ctttcccgac cagaatgatg tgatccaagc caggaaagcc
    15421 tacgacctac agagcgacag tgtgtataag gcagacctgg agtggctgcg tggcatcggc
    15481 tggatgccag aaggctcagt ggaaatgaac agagtgaagg ttgctcaaga cctcgtgaat
    15541 gaaagactct ataggacacg tccagaagct ttgtcattca ccagcattgt cgacactcca
    15601 gaagttgtct tggcaaaagc caattctctg caaataagtg agaaactgta tcaggaagcc
    15661 tggaataaag ataaaagcaa catcaccatt ccttctgata ctccggagat gctgcaggcc
    15721 cacatcaatg ccttgcaaat cagcaataaa ctctaccaaa aagactggaa tgacaccaag
    15781 cagaaaggct atgacataag ggcagatgcc attgaaatca agcacgccaa ggcctccaga
    15841 gaaattgcca gtgagtacaa atacaaagaa ggttaccgta agcaactggg ccaccacatg
    15901 ggtttccgca ccctacaaga tgaccccaag tcagtatggg ctatacatgc tgccaagatc
    15961 cagagtgaca gagaatataa gaaagcttat gagaagtcta aaggaattca caacacaccg
    16021 ttggacatga tgtcaattgt tcaagccaag aaatgccagg tcctggttag cgacattgat
    16081 tatcgcaatt atctgcacca gtggacgtgt ctgccagatc agaacgatgt gatccaggcc
    16141 aagaaagcct acgacctgca gagcgataac ttgtacaagt cagacctgga atggctgaag
    16201 ggtattggat ggttgccaga gggttctgtg gaagtgatga gagtgaagaa tgcccagaat
    16261 ctcttgaatg aaaggctgta tcgtataaag cctgaggccc tcaaattcac cagcattgtt
    16321 gacaccccgg aagtaatcca ggcaaagatc aatgctgtac agatcagtga gccattgtat
    16381 cgcgatgcct gggagaaaga gaaggctaat gtgaacgtgc cagctgacac tcccctgatg
    16441 ctgcaatcca aaatcaatgc cctgcagatc agcaataaac gctatcagca agcttgggaa
    16501 gatgtcaaga tgactggtta tgacctgcga gcagatgcca ttgggatcca gcatgccaag
    16561 gcttccaggg atattgccag tgactatctg tacaaaactg cttatgagaa acagaaaggc
    16621 cattacattg gctgtcgcag cgccaaggaa gaccctaaac tggtttgggc agcaaatgtg
    16681 ttgaagatgc agaatgacag gctgtacaaa aaggcctaca acgaccacaa agccaagatc
    16741 tccatccctg tggacatggt gtccatcagc gctgccaaag aaggtcaggc actggcaagt
    16801 gatgtggact atcgccatta cctgcaccgc tggtcttgct ttcccgacca gaatgatgtg
    16861 atccaagcca ggaaagccta cgacctacag agcgacgccc tctacaaggc tgacttggag
    16921 tggttgcgtg gcattggctg gatgccccaa gggtctcctg aagtgttgag agtcaaaaac
    16981 gcccagaata tcttttgtga cagtgtctat cggacgcctg tggtgaacct taagtacaca
    17041 agcattgttg acacacctga agtggtcctt gctaaatcaa atgctgaaaa tattagtatt
    17101 ccaaagtaca gagaggtttg ggacaaggat aaaacttcaa tacacataat gccagatact
    17161 ccagaaatta atctcgctag agcaaatgct cttaatgtga gcaataaact ttaccgtgag
    17221 ggctgggatg aaatgaaggc gggctgtgat gtccggctgg atgccatccc catccaggct
    17281 gccaaggcct ccagggagat tgccagtgac tataaatata agcttgacca tgagaagcag
    17341 aagggacact acgtgggcac cctcacagcc agggatgaca acaagatccg ctgggccctc
    17401 atagctgaca agctccagaa tgaacgagag taccggctgg actgggccaa atggaaggcc
    17461 aagatccaga gccctgtgga catgctttcc atcctgcact ctaaaaattc ccaggctctg
    17521 gtcagtgaca tggattaccg caattacctg caccagtgga cctgcatgcc cgaccagaac
    17581 gatgtgattc aggccaagaa ggcctacgaa ctgcagagcg ataatgttta caaggctgac
    17641 ttggaatggt tgcgtggaat tgggtggatg ccaaatgact ccgtgtccgt caatcatgcc
    17701 aaacatgccg cggacatctt cagtgagaaa aaatatcgca caaaaataga aactctcaac
    17761 tttacgcctg tggatgacag agttgattat gtgacagcga aacaaagtgg cgagatcctc
    17821 gatgatatta aataccggaa agactggaat gccaccaaat caaagtacac cctcacagaa
    17881 acccccctgc tgcacactgc ccaggaggct gctaggatac tggaccagta tctctacaag
    17941 gaaggctggg agagacaaaa agccacaggt tacattttgc ctccagatgc tgtgccattt
    18001 gttcatgccc atcactgcaa tgacgttcag agtgagctga aatacaaagc tgaacatgtg
    18061 aagcaaaaag gtcattatgt tggtgtcccg acgatgagag atgatcctaa gctggtttgg
    18121 tttgagcatg caggccagat tcagaatgag agactataca aagaggacta tcacaaaaca
    18181 aaggccaaaa tcaatatacc tgctgatatg gtgtcagtct tggccgccaa gcaggggcag
    18241 acccttgtca gtgatattga ttatcgtaat tacttgcacc aatggatgtg tcatcctgac
    18301 cagaacgatg ttattcaggc aagaaaggcc tatgacctac agagtgataa tgtctacaga
    18361 gctgacctgg agtggctccg aggcattggc tggatcccac tggattctgt ggaccatgta
    18421 agggttacta agaaccagga aatgatgagt cagatcaaat ataagaaaaa tgcccttgaa
    18481 aactatccta actttagaag tgtggtggat cctccagaga ttgttttagc caagattaat
    18541 tctgtcaatc aaagtgatgt aaaatataaa gaaacattta ataaagcaaa gggcaaatat
    18601 acgttttcac cagatacacc acatatctcc cactccaaag acatgggaaa actctacagt
    18661 actatactgt ataaaggggc gtgggagggc accaaggcct atggctacac cctggatgag
    18721 cgctacattc ccattgttgg agccaagcat gctgatctgg tgaacagtga gcttaaatac
    18781 aaagagacat atgagaagca gaaaggtcac tacctggctg gaaaagtgat cggtgaattc
    18841 cctggtgtgg ttcactgtct ggatttccaa aagatgagga gtgcgttgaa ctacagaaaa
    18901 cattatgagg ataccaaagc aaatgttcat atccccaatg acatgatgaa tcacgtgctg
    18961 gctaaaaggt gccagtacat cctcagtgac ctggagtatc gacactattt ccaccagtgg
    19021 acgtctcttc tggaagaacc caatgttata cgcgtccgaa acgcccagga gatcttgagt
    19081 gataatgtgt ataaagatga cctgaattgg ttgaaaggca ttggttgcta cgtttgggat
    19141 acaccccaaa tcctccatgc caagaaatca tacgaccttc agagtcagct acaatataca
    19201 gcagcaggta aagaaaatct acaaaactat aatctggtca cagacacgcc cctctatgtg
    19261 actgctgttc agagtggcat taatgccagt gaggtaaaat ataaagaaaa ttatcatcag
    19321 attaaggaca aatacacaac agttctagaa acagtggatt atgacagaac cagaaacctg
    19381 aagaatcttt acagcagtaa cctgtacaag gaggcctggg atagagtgaa agccaccagc
    19441 tacatcctgc cttccagcac cttgtccctg acacacgcca agaaccagaa gcatctggcc
    19501 agccatatca aatatcggga agaatatgaa aagttcaaag ctctttatac gttaccaaga
    19561 agtgttgacg atgatccgaa cacagcacgg tgcctccgag ttggcaagct taacatcgat
    19621 cgcctgtaca gatcagttta tgaaaagaac aagatgaaaa tccacatcgt gcccgacatg
    19681 gtagagatgg ttactgccaa ggattcccag aagaaagtca gtgagattga ttaccgcctg
    19741 cgcctccacg aatggatttg ccaccccgac ttgcaagtca atgatcacgt caggaaagtc
    19801 acagatcaga tcagcgatat tgtatacaag gatgacctca actggctgaa aggcattggt
    19861 tgctacgtct gggacactcc tgaaatcctc catgccaagc atgcttatga tctacgtgat
    19921 gatatcaagt ataaagctca catgttgaaa acaaggaatg actacaagct tgtcacagat
    19981 acaccagtct acgtgcaggc tgtcaaaagt gggaaacagc taagtgacgc tgtctaccac
    20041 tatgactatg tgcacagtgt cagaggcaaa gtggctccaa ctaccaaaac cgtggatctg
    20101 gaccgggccc ttcatgcata caagctccag agttcgaatc tatacaaaac cagcctgcgc
    20161 accctgccca ctggatatag acttccaggt gacactcctc acttcaaaca catcaaggac
    20221 acccgttaca tgagcagtta tttcaagtac aaagaagcct atgaacacac caaggcatat
    20281 gggtatacac ttggccccaa agatgttcca tttgtccacg tccggagagt caacaatgtt
    20341 accagcgaga gactgtatcg ggaattgtac cacaaactga aagacaagat ccatacaact
    20401 cccgataccc ctgagatccg ccaagtcaag aagacacaag aggctgtcag tgagttgatc
    20461 tacaaatcag acttcttcaa gatgcagggc cacatgatct ctctgccata cacaccccaa
    20521 gtgatccatt gccgctatgt gggagacatc accagtgata ttaaatacaa agaggacttg
    20581 caggtcctga agggatttgg ctgcttcctg tatgacactc ctgacatggt ccgctcccgg
    20641 cacctgcgga agctctggtc taattaccta tacactgata aggcaaggaa gatgcgagac
    20701 aaatacaaag tggtgcttga cactccagaa tacagaaaag tgcaagaact gaagacacat
    20761 ctgagtgagc tggtctacag agctgcaggc aagaagcaga agtcaatctt tacttcagtt
    20821 cctgatactc ctgatctttt aagagccaag cgagggcaga agcttcagag tcagtatctg
    20881 tatgttgaac ttgccaccaa agagagaccc catcatcacg ctggaaacca gaccacagcc
    20941 ttgaagcatg ctaaagacgt gaaggacatg gtcagtgaga aaaagtacaa gattcaatat
    21001 gaaaagatga aagacaagta cactccggtt ccagatacgc caatcctcat cagagccaag
    21061 agggcttact ggaatgccag tgatctacgc tacaaagaaa catttcaaaa gaccaaaggg
    21121 aaataccaca cggtgaaaga tgccctagac attgtctatc atcgcaaagt cacagatgac
    21181 atcagtaaaa taaaatacaa ggagaactac atgagccagt tgggtatctg gaggtccatt
    21241 cctgatcgtc cagagcattt ccaccaccga gcagtcactg acacagtcag tgatgtaaaa
    21301 tataaagaag acttgacttg gcttaaaggc attggttgct atgcctatga tacccctgat
    21361 ttcactctgg ctgaaaagaa caagactctc tacagcaagt ataagtataa agaagtattt
    21421 gaaaggacaa agtcagattt caagtatgtt gccgactctc cgatcaatag gcatttcaag
    21481 tatgcaactc aattgatgaa tgagagaaaa tataaatcta gtgccaagat gtttctgcaa
    21541 catggatgta atgaaattct gcgtccagat atgttgactg ctctctacaa ttcgcatatg
    21601 tggagccaga tcaaatacag gaaaaactat gaaaaatcaa aggacaaatt tacctcaatt
    21661 gtggatactc cagaacacct gcgtactaca aaagtcaaca aacaaatcag cgatatcctt
    21721 tataaattgg aatacaacaa ggccaaaccc agaggctaca ccacaatcca cgacacaccc
    21781 atgttgctgc atgtccgcaa ggttaaagat gaagtcagtg atctgaaata caaagaagta
    21841 taccaaagaa ataaatccaa ctgcaccatt gagccagatg ctgttcatat caaagcagcc
    21901 aaggacgcct acaaagtcaa caccaatctg gactataaga aacagtacga agccaacaaa
    21961 gcccactgga agtggactcc tgaccgaccg gacttcctcc aggctgccaa gtcatccctg
    22021 cagcaaagcg attttgaata taagctggac cgggagttcc tcaagggttg caagctttct
    22081 gtcactgatg acaaaaacac ggtgctcgcc ctcaggaata ctttaataga aagtgatctg
    22141 aaatacaaag agaaacatgt caaggaaaga ggaacctgcc atgccgtacc tgacacgcct
    22201 cagatcctgc tggcgaagac tgtcagcaac ctggtgtctg agaacaagta caaggaccat
    22261 gtcaagaagc acttggcaca gggctcatac acaacactac cagagacccg ggacactgtt
    22321 cacgtcaagg aagtgaccaa gcatgtcagt gatacaaatt acaaaaagaa gtttgtcaag
    22381 gagaaaggaa aatccaacta ctccatcatg ctggagccac cagaggtgaa acatgctatg
    22441 gaagtggcca agaagcaaag tgatgtcgct tacagaaaag atgccaaaga gaacctgcat
    22501 tacaccacag tggctgatcg accagacatc aagaaggcca cacaggcagc caaacaggcc
    22561 agtgaggtgg agtacagagc caagcaccgc aaggaaggca gccatggctt aagcatgctc
    22621 ggtcgcccag acatagaaat ggccaagaag gcagccaagc tgagcagcca ggttaaatac
    22681 cgagaaaatt tcgataaaga aaagggcaag acaccaaaat acaatccaaa agacagccag
    22741 ctctacaaag tcatgaaaga tgctaataat cttgcaagtg aggttaaata caaggctgac
    22801 ctgaagaaac ttcacaaacc cgtgactgac atgaaggagt ctctgatcat gaatcatgtc
    22861 ctgaatacaa gccaacttgc cagttcttac cagtacaaga agaagtatga gaagagtaaa
    22921 ggccactacc acaccatacc cgataatctg gagcagcttc acctaaaaga ggccacagaa
    22981 ttacagagta tagtgaaata caaagaaaag tatgaaaagg aacgaggaaa acccatgctg
    23041 gactttgaaa caccaacgta catcactgcc aaagagtctc agcagatgca gagtgggaaa
    23101 gaatatagga aagattatga agagtccatt aaaggcagaa acctgactgg cctggaggtc
    23161 acgccagctt tgttacatgt caaatatgca actaaaatag caagcgagaa agagtacagg
    23221 aaagatctag aggaaagcat ccgtgggaag ggcctcactg aaatggaaga tacacctgac
    23281 atgctaagag caaagaatgc cactcaaatc ctcaatgaga aagaatataa gcgagacctg
    23341 gaactggaag tcaaaggaag aggcctgaat gccatggcca atgaaactcc ggattttatg
    23401 agggccagga atgctactga tattgccagt cagattaagt ataagcaatc agcagaaatg
    23461 gagaaagcca atttcacttc tgtggttgat actccagaga tcattcatgc ccaacaagtc
    23521 aagaatcttt caagccagaa aaagtacaag gaagatgctg agaagtccat gtcgtattat
    23581 gagactgttt tggacacccc agagatacag agagtccggg agaaccaaaa gaacttcagc
    23641 cttctccaat accagtgtga ccttaaaaac agtaaaggaa aaattacagt tgttcaagac
    23701 acgccagaaa tactgcgtgt aaaagaaaat cagaagaatt tcagctcggt tttatataaa
    23761 gaggatgtct caccaggaac ggctatcgga aagacacctg agatgatgag agtgaaacaa
    23821 acacaggacc acattagctc ggtgaagtat aaggaagcaa taggacaagg aactccaatc
    23881 cctgacctgc ctgaagtgaa acgtgtgaag gagacgcaga agcacattag ctcggttatg
    23941 tacaaagaaa acttgggaac aggcattcca accactgtga ctccagagat tgagagagtc
    24001 aaacgcaatc aagagaactt tagctcggtt ttgtacaaag aaaatttggg gaaaggaatc
    24061 ccaacaccta tcactccaga gatggagaga gtcaaacgca atcaagagaa ctttagctcg
    24121 atattgtaca aagagaactt gagcaagggg actcccctac ctgtcactcc tgagatggag
    24181 cgagtcaaac tcaatcaaga aaactttagc tcggtgttgt ataaagaaaa cgttggaaaa
    24241 gggattccaa tccccatcac tccagagatg gagagagtca aacacaatca agaaaacttt
    24301 agttcggtgc tatacaaaga aaacctgggg acaggaattc caatccccat cactcctgag
    24361 atgcagagag tcaaacacaa tcaagaaaac cttagctcgg tgttatacaa agaaaacatg
    24421 ggcaagggaa cccctttacc tgtcactccc gagatggaaa gagtcaaaca caatcaagaa
    24481 aatattagct cggtgttata caaagaaaac atgggcaagg gaacccctct acctgtcact
    24541 cctgagatgg agagagtcaa acacaatcaa gaaaatatta gctcggtgtt atacaaagaa
    24601 aacatgggca agggaactcc tttagctgtc actcccgaga tggagcgagt caaacacaat
    24661 caagaaaata ttagctcggt tttgtacaaa gaaaatgtgg ggaaagccac cgcaacccct
    24721 gtcactcctg agatgcagag agtcaaacgc aatcaagaaa acattagctc ggtgttatac
    24781 aaagagaacc tggggaaagc aacccccaca ccctttactc ctgagatgga aagagtgaaa
    24841 cgcaatcaag aaaactttag ctcggtattg tacaaagaga acatgagaaa agcaactccg
    24901 acacctgtta ctccagagat ggagagagct aagcgcaacc aagaaaacat tagctcggtt
    24961 ctttattctg atagtttccg gaaacaaata caaggcaaag ctgcctatgt attggatacc
    25021 cccgagatga gacgggtgag ggagacccaa cggcacatct caacggtgaa atatcatgaa
    25081 gactttgaga aacacaaggg ttgcttcaca ccagtggtga cagatcctat cactgaacga
    25141 gtaaagaaga acatgcagga cttcagtgac attaactacc gaggtattca gaggaaagtg
    25201 gtagaaatgg aacaaaaacg gaatgaccaa gatcaggaga ctattacagg tttacgtgtc
    25261 tggcgtacta atcctggttc ggtttttgac tatgatccag cagaagacaa catccagtcc
    25321 cgaagcttac acatgattaa tgtccaagct cagcgccgga gccgggagca gtcacgatct
    25381 gccagtgcac taagcatcag tgggggtgag gagaagtctg agcattcaga agcaccagac
    25441 caccaccttt cgacttacag cgacgggggt gtctttgcag tctcaacagc ttacaaacat
    25501 gcaaaaacca cagagctccc acaacaacga tcatcttcag ttgctaccca acagacaacg
    25561 gtatcttcca tcccatctca tccatctact gctggaaaaa tcttccgtgc catgtatgac
    25621 tatatggctg ctgatgcaga tgaggtgtcc ttcaaggatg gagatgccat cataaatgtt
    25681 caagcaattg atgaaggctg gatgtatggc actgtgcaga ggactggcag gaccggaatg
    25741 ctcccagcca actacgttga agctatttag gcatttcaaa gcatcacact tgtctgcagg
    25801 acttacagat cctgcagtca atgtttcggt ttagactctc cactgttacc taagttctca
    25861 agctgcctat ggtttttctg tgtcaatgtg atttatggta gtaccatcct ttctcctttg
    25921 ggttttaaaa taagttgcag aacagacact ttaaaagctt ctgcaatatt atttctgtgc
    25981 ctagagtctt tctccattat aaacatgttt taacattatt tcttttctaa aacagggatt
    26041 ttgaatatgc caaacacatt aaaggaaaaa tagcagagat gttcaccttt tccttgctga
    26101 ttgctaatgc ttattatttc taattcagtt ctgaagttat aaacttataa tcaatacaaa
    26161 ccagcaacta ataaaacctc taattctgca a
//
