LOCUS       NM_001206654            8971 bp    mRNA    linear   PRI 11-DEC-2024
DEFINITION  Homo sapiens nuclear receptor corepressor 2 (NCOR2), transcript
            variant 3, mRNA.
ACCESSION   NM_001206654
VERSION     NM_001206654.2
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 8971)
  AUTHORS   Patton,A., Ilaslan,H., Armstrong,S.M., Bakhshwin,A., Cheng,Y.W.,
            Minhas,F. and Fritchie,K.J.
  TITLE     Keratin-Positive Giant Cell-Rich Tumor of Bone Harboring an
            HMGA2::NCOR2 Fusion: Two Cases, Including a Patient With Metastatic
            Disease, and Review of the Literature
  JOURNAL   Int J Surg Pathol 32 (3), 556-564 (2024)
   PUBMED   37461232
  REMARK    GeneRIF: Keratin-Positive Giant Cell-Rich Tumor of Bone Harboring
            an HMGA2::NCOR2 Fusion: Two Cases, Including a Patient With
            Metastatic Disease, and Review of the Literature.
            Review article
REFERENCE   2  (bases 1 to 8971)
  AUTHORS   Kliche,J., Garvanska,D.H., Simonetti,L., Badgujar,D.,
            Dobritzsch,D., Nilsson,J., Davey,N.E. and Ivarsson,Y.
  TITLE     Large-scale phosphomimetic screening identifies phospho-modulated
            motif-based protein interactions
  JOURNAL   Mol Syst Biol 19 (7), e11164 (2023)
   PUBMED   37219487
REFERENCE   3  (bases 1 to 8971)
  AUTHORS   Lee,R.D., Knutson,T.P., Munro,S.A., Miller,J.T.,
            Heltemes-Harris,L.M., Mullighan,C.G., Jepsen,K. and Farrar,M.A.
  TITLE     Nuclear corepressors NCOR1/NCOR2 regulate B cell development,
            maintain genomic integrity and prevent transformation
  JOURNAL   Nat Immunol 23 (12), 1763-1776 (2022)
   PUBMED   36316474
  REMARK    GeneRIF: Nuclear corepressors NCOR1/NCOR2 regulate B cell
            development, maintain genomic integrity and prevent transformation.
REFERENCE   4  (bases 1 to 8971)
  AUTHORS   Tsai,K.K., Huang,S.S., Northey,J.J., Liao,W.Y., Hsu,C.C.,
            Cheng,L.H., Werner,M.E., Chuu,C.P., Chatterjee,C., Lakins,J.N. and
            Weaver,V.M.
  TITLE     Screening of organoids derived from patients with breast cancer
            implicates the repressor NCOR2 in cytotoxic stress response and
            antitumor immunity
  JOURNAL   Nat Cancer 3 (6), 734-752 (2022)
   PUBMED   35618935
  REMARK    GeneRIF: Screening of organoids derived from patients with breast
            cancer implicates the repressor NCOR2 in cytotoxic stress response
            and antitumor immunity.
REFERENCE   5  (bases 1 to 8971)
  AUTHORS   Jiang,Q., Galiegue-Zouitina,S., Roumier,C., Hildebrand,M.P.,
            Thomas,S. and Coignet,L.J.
  TITLE     Genomic organization and refined mapping of the human nuclear
            corepressor 2 (NCOR2)/ silencing mediator of retinoid and thyroid
            hormone receptor (SMRT) gene on chromosome 12q24.3
  JOURNAL   Cytogenet Cell Genet 92 (3-4), 217-220 (2001)
   PUBMED   11435691
REFERENCE   6  (bases 1 to 8971)
  AUTHORS   Ordentlich,P., Downes,M., Xie,W., Genin,A., Spinner,N.B. and
            Evans,R.M.
  TITLE     Unique forms of human and mouse nuclear receptor corepressor SMRT
  JOURNAL   Proc Natl Acad Sci U S A 96 (6), 2639-2644 (1999)
   PUBMED   10077563
REFERENCE   7  (bases 1 to 8971)
  AUTHORS   Margolis,R.L., Abraham,M.R., Gatchell,S.B., Li,S.H., Kidwai,A.S.,
            Breschel,T.S., Stine,O.C., Callahan,C., McInnis,M.G. and Ross,C.A.
  TITLE     cDNAs with long CAG trinucleotide repeats from human brain
  JOURNAL   Hum Genet 100 (1), 114-122 (1997)
   PUBMED   9225980
REFERENCE   8  (bases 1 to 8971)
  AUTHORS   Sande,S. and Privalsky,M.L.
  TITLE     Identification of TRACs (T3 receptor-associating cofactors), a
            family of cofactors that associate with, and modulate the activity
            of, nuclear hormone receptors
  JOURNAL   Mol Endocrinol 10 (7), 813-825 (1996)
   PUBMED   8813722
REFERENCE   9  (bases 1 to 8971)
  AUTHORS   Chen,J.D. and Evans,R.M.
  TITLE     A transcriptional co-repressor that interacts with nuclear hormone
            receptors
  JOURNAL   Nature 377 (6548), 454-457 (1995)
   PUBMED   7566127
REFERENCE   10 (bases 1 to 8971)
  AUTHORS   Horlein,A.J., Naar,A.M., Heinzel,T., Torchia,J., Gloss,B.,
            Kurokawa,R., Ryan,A., Kamei,Y., Soderstrom,M., Glass,C.K. et al.
  TITLE     Ligand-independent repression by the thyroid hormone receptor
            mediated by a nuclear receptor co-repressor
  JOURNAL   Nature 377 (6548), 397-404 (1995)
   PUBMED   7566114
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from AC073592.11, AC069261.37 and
            AC073916.41.
            
            On Jan 8, 2019 this sequence version replaced NM_001206654.1.
            
            Summary: This gene encodes a nuclear receptor co-repressor that
            mediates transcriptional silencing of certain target genes. The
            encoded protein is a member of a family of thyroid hormone- and
            retinoic acid receptor-associated co-repressors. This protein acts
            as part of a multisubunit complex which includes histone
            deacetylases to modify chromatin structure that prevents basal
            transcriptional activity of target genes. Aberrant expression of
            this gene is associated with certain cancers. Alternate splicing
            results in multiple transcript variants encoding different
            isoforms.[provided by RefSeq, Apr 2011].
            
            Transcript Variant: This variant (3) has multiple difference in the
            coding region, but maintains the reading frame, compared to variant
            1. The resulting isoform (3) has the same N- and C-termini but is
            shorter than isoform 1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            CDS exon combination :: AF125672.1 [ECO:0000331]
            RNAseq introns       :: mixed sample support SAMEA1965299,
                                    SAMEA1966682 [ECO:0006172]
            ##Evidence-Data-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-305               AC073592.11        70074-70378         c
            306-352             AC073592.11        38331-38377         c
            353-574             AC069261.37        3871-4092
            575-702             AC073916.41        201700-201827       c
            703-880             AC073916.41        198855-199032       c
            881-1060            AC073916.41        188211-188390       c
            1061-1174           AC073916.41        181432-181545       c
            1175-1231           AC073916.41        172365-172421       c
            1232-1284           AC073916.41        165074-165126       c
            1285-1351           AC073916.41        153189-153255       c
            1352-1524           AC073916.41        145874-146046       c
            1525-1615           AC073916.41        144872-144962       c
            1616-1794           AC073916.41        141881-142059       c
            1795-1849           AC073916.41        137760-137814       c
            1850-1948           AC073916.41        135216-135314       c
            1949-2106           AC073916.41        117663-117820       c
            2107-2279           AC073916.41        115760-115932       c
            2280-2342           AC073916.41        113378-113440       c
            2343-2485           AC073916.41        101004-101146       c
            2486-2633           AC073916.41        93496-93643         c
            2634-3222           AC073916.41        87281-87869         c
            3223-3343           AC073916.41        78938-79058         c
            3344-3515           AC073916.41        77385-77556         c
            3516-3680           AC073916.41        71901-72065         c
            3681-3820           AC073916.41        70691-70830         c
            3821-3923           AC073916.41        70096-70198         c
            3924-4028           AC073916.41        69737-69841         c
            4029-4132           AC073916.41        69352-69455         c
            4133-4283           AC073916.41        65846-65996         c
            4284-4424           AC073916.41        63433-63573         c
            4425-4511           AC073916.41        63084-63170         c
            4512-4798           AC073916.41        61823-62109         c
            4799-5153           AC073916.41        59856-60210         c
            5154-5375           AC073916.41        58264-58485         c
            5376-5627           AC073916.41        57082-57333         c
            5628-5777           AC073916.41        55861-56010         c
            5778-5927           AC073916.41        55553-55702         c
            5928-6126           AC073916.41        55265-55463         c
            6127-6554           AC073916.41        52012-52439         c
            6555-6704           AC073916.41        50742-50891         c
            6705-6850           AC073916.41        50394-50539         c
            6851-7044           AC073916.41        49683-49876         c
            7045-7194           AC073916.41        48389-48538         c
            7195-7343           AC073916.41        47578-47726         c
            7344-7397           AC073916.41        46104-46157         c
            7398-7622           AC073916.41        42668-42892         c
            7623-7802           AC073916.41        41450-41629         c
            7803-8971           AC073916.41        39674-40842         c
FEATURES             Location/Qualifiers
     source          1..8971
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="12"
                     /map="12q24.31"
     gene            1..8971
                     /gene="NCOR2"
                     /gene_synonym="CTG26; N-CoR2; SMAP270; SMRT; SMRTE;
                     SMRTE-tau; TNRC14; TRAC; TRAC-1; TRAC1"
                     /note="nuclear receptor corepressor 2"
                     /db_xref="GeneID:9612"
                     /db_xref="HGNC:HGNC:7673"
                     /db_xref="MIM:600848"
     exon            1..305
                     /gene="NCOR2"
                     /gene_synonym="CTG26; N-CoR2; SMAP270; SMRT; SMRTE;
                     SMRTE-tau; TNRC14; TRAC; TRAC-1; TRAC1"
                     /inference="alignment:Splign:2.1.0"
     exon            306..352
                     /gene="NCOR2"
                     /gene_synonym="CTG26; N-CoR2; SMAP270; SMRT; SMRTE;
                     SMRTE-tau; TNRC14; TRAC; TRAC-1; TRAC1"
                     /inference="alignment:Splign:2.1.0"
     exon            353..574
                     /gene="NCOR2"
                     /gene_synonym="CTG26; N-CoR2; SMAP270; SMRT; SMRTE;
                     SMRTE-tau; TNRC14; TRAC; TRAC-1; TRAC1"
                     /inference="alignment:Splign:2.1.0"
     CDS             470..7984
                     /gene="NCOR2"
                     /gene_synonym="CTG26; N-CoR2; SMAP270; SMRT; SMRTE;
                     SMRTE-tau; TNRC14; TRAC; TRAC-1; TRAC1"
                     /note="isoform 3 is encoded by transcript variant 3;
                     silencing mediator for retinoid and thyroid hormone
                     receptors; CTG repeat protein 26; T3 receptor-associating
                     factor; thyroid-, retinoic-acid-receptor-associated
                     corepressor"
                     /codon_start=1
                     /product="nuclear receptor corepressor 2 isoform 3"
                     /protein_id="NP_001193583.1"
                     /db_xref="CCDS:CCDS55892.1"
                     /db_xref="GeneID:9612"
                     /db_xref="HGNC:HGNC:7673"
                     /db_xref="MIM:600848"
                     /translation="MSGSTQPVAQTWRATEPRYPPHSLSYPVQIARTHTDVGLLEYQH
                     HSRDYASHLSPGSIIQPQRRRPSLLSEFQPGNERSQELHLRPESHSYLPELGKSEMEF
                     IESKRPRLELLPDPLLRPSPLLATGQPAGSEDLTKDRSLTGKLEPVSPPSPPHTDPEL
                     ELVPPRLSKEELIQNMDRVDREITMVEQQISKLKKKQQQLEEEAAKPPEPEKPVSPPP
                     IESKHRSLVQIIYDENRKKAEAAHRILEGLGPQVELPLYNQPSDTRQYHENIKINQAM
                     RKKLILYFKRRNHARKQWEQKFCQRYDQLMEAWEKKVERIENNPRRRAKESKVREYYE
                     KQFPEIRKQRELQERMQRVGQRGSGLSMSAARSEHEVSEIIDGLSEQENLEKQMRQLA
                     VIPPMLYDADQQRIKFINMNGLMADPMKVYKDRQVMNMWSEQEKETFREKFMQHPKNF
                     GLIASFLERKTVAECVLYYYLTKKNENYKSLVRRSYRRRGKSQQQQQQQQQQQQQQQQ
                     QPMPRSSQEEKDEKEKEKEAEKEEEKPEVENDKEDLLKEKTDDTSGEDNDEKEAVASK
                     GRKTANSQGRRKGRITRSMANEANSEEAITPQQSAELASMELNESSRWTEEEMETAKK
                     GLLEHGRNWSAIARMVGSKTVSQCKNFYFNYKKRQNLDEILQQHKLKMEKERNARRKK
                     KKAPAAASEEAAFPPVVEDEEMEASGVSGNEEEMVEEAEATVNNSSDTESIPSPHTEA
                     AKDTGQNGPKPPATLGADGPPPGPPTPPPEDIPAPTEPTPASEATGAPTPPPAPPSPS
                     APPPVVPKEEKEEETAAAPPVEEGEEQKPPAAEELAVDTGKAEEPVKSECTEEAEEGP
                     AKGKDAEAAEATAEGALKAEKKEGGSGRATTAKSSGAPQDSDSSATCSADEVDEAEGG
                     DKNRLLSPRPSLLTPTGDPRANASPQKPLDLKQLKQRAAAIPPIQVTKVHEPPREDAA
                     PTKPAPPAPPPPQNLQPESDAPQQPGSSPRGKSRSPAPPADKEAEKPVFFPAFAAEAQ
                     KLPGDPPCWTSGLPFPVPPREVIKASPHAPDPSAFSYAPPGHPLPLGLHDTARPVLPR
                     PPTISNPPPLISSAKHPSVLERQIGAISQGMSVQLHVPYSEHAKAPVGPVTMGLPLPM
                     DPKKLAPFSGVKQEQLSPRGQAGPPESLGVPTAQEASVLRGTALGSVPGGSITKGIPS
                     TRVPSDSAITYRGSITHGTPADVLYKGTITRIIGEDSPSRLDRGREDSLPKGHVIYEG
                     KKGHVLSYEGGMSVTQCSKEDGRSSSGPPHETAAPKRTYDMMEGRVGRAISSASIEGL
                     MGRAIPPERHSPHHLKEQHHIRGSITQGIPRSYVEAQEDYLRREAKLLKREGTPPPPP
                     PSRDLTEAYKTQALGPLKLKPAHEGLVATVKEAGRSIHEIPREELRHTPELPLAPRPL
                     KEGSITQGTPLKYDTGASTTGSKKHDVRSLIGSPGRTFPPVHPLDVMADARALERACY
                     EESLKSRPGTASSSGGSIARGAPVIVPELGKPRQSPLTYEDHGAPFAGHLPRGSPVTT
                     REPTPRLQEGSLSSSKASQDRKLTSTPREIAKSPHSTVPEHHPHPISPYEHLLRGVSG
                     VDLYRSHIPLAFDPTSIPRGIPLDAAAAYYLPRHLAPNPTYPHLYPPYLIRGYPDTAA
                     LENRQTIINDYITSQQMHHNAATAMAQRADMLRGLSPRESSLALNYAAGPRGIIDLSQ
                     VPHLPVLVPPTPGTPATAMDRLAYLPTAPQPFSSRHSSSPLSPGGPTHLTKPTTTSSS
                     ERERDRDRERDRDREREKSILTSTTTVEHAPIWRPGTEQSSGSSGGGGGSSSRPASHS
                     HAHQHSPISPRTQDALQQRPSVLHNTGMKGIITAVEPSTPTVLRSTSTSSPVRPAATF
                     PPATHCPLGGTLDGVYPTLMEPVLLPKEAPRVARPERPRADTGHAFLAKPPARSGLEP
                     ASSPSKGSEPRPLVPPVSGHATIARTPAKNLAPHHASPDPPAPPASASDPHREKTQSK
                     PFSIQELELRSLGYHGSSYSPEGVEPVSPVSSPSLTHDKGLPKHLEELDKSHLEGELR
                     PKQPGPVKLGGEAAHLPHLRPLPESQPSSSPLLQTAPGVKGHQRVVTLAQHISEVITQ
                     DYTRHHPQQLSAPLPAPLYSFPGASCPVLDLRRPPSDLYLPPPDHGAPARGSPHSEGG
                     KRSPEPNKTSVLGGGEDGIEPVSPPEGMTEPGHSRSAVYPLLYRDGEQTEPSRMGSKS
                     PGNTSQPPAFFSKLTESNSAMVKSKKQEINKKLNTHNRNEPEYNISQPGTEIFNMPAI
                     TGTGLMTYRSQAVQEHASTNMGLEAIIRKALMGKYDQWEESPPLSANAFNPLNASASL
                     PAAMPITAADGRSDHTLTSPGGGGKAKVSGRPSSRKAKSPAPGLASGDRPPSVSSVHS
                     EGDCNRRTPLTNRVWEDRPSSAGSTPFPYNPLIMRLQAGVMASPPPPGLPAGSGPLAG
                     PHHAWDEEPKPLLCSQYETLSDSE"
     exon            575..702
                     /gene="NCOR2"
                     /gene_synonym="CTG26; N-CoR2; SMAP270; SMRT; SMRTE;
                     SMRTE-tau; TNRC14; TRAC; TRAC-1; TRAC1"
                     /inference="alignment:Splign:2.1.0"
     exon            703..880
                     /gene="NCOR2"
                     /gene_synonym="CTG26; N-CoR2; SMAP270; SMRT; SMRTE;
                     SMRTE-tau; TNRC14; TRAC; TRAC-1; TRAC1"
                     /inference="alignment:Splign:2.1.0"
     exon            881..1060
                     /gene="NCOR2"
                     /gene_synonym="CTG26; N-CoR2; SMAP270; SMRT; SMRTE;
                     SMRTE-tau; TNRC14; TRAC; TRAC-1; TRAC1"
                     /inference="alignment:Splign:2.1.0"
     exon            1061..1174
                     /gene="NCOR2"
                     /gene_synonym="CTG26; N-CoR2; SMAP270; SMRT; SMRTE;
                     SMRTE-tau; TNRC14; TRAC; TRAC-1; TRAC1"
                     /inference="alignment:Splign:2.1.0"
     exon            1175..1231
                     /gene="NCOR2"
                     /gene_synonym="CTG26; N-CoR2; SMAP270; SMRT; SMRTE;
                     SMRTE-tau; TNRC14; TRAC; TRAC-1; TRAC1"
                     /inference="alignment:Splign:2.1.0"
     exon            1232..1284
                     /gene="NCOR2"
                     /gene_synonym="CTG26; N-CoR2; SMAP270; SMRT; SMRTE;
                     SMRTE-tau; TNRC14; TRAC; TRAC-1; TRAC1"
                     /inference="alignment:Splign:2.1.0"
     exon            1285..1351
                     /gene="NCOR2"
                     /gene_synonym="CTG26; N-CoR2; SMAP270; SMRT; SMRTE;
                     SMRTE-tau; TNRC14; TRAC; TRAC-1; TRAC1"
                     /inference="alignment:Splign:2.1.0"
     exon            1352..1524
                     /gene="NCOR2"
                     /gene_synonym="CTG26; N-CoR2; SMAP270; SMRT; SMRTE;
                     SMRTE-tau; TNRC14; TRAC; TRAC-1; TRAC1"
                     /inference="alignment:Splign:2.1.0"
     exon            1525..1615
                     /gene="NCOR2"
                     /gene_synonym="CTG26; N-CoR2; SMAP270; SMRT; SMRTE;
                     SMRTE-tau; TNRC14; TRAC; TRAC-1; TRAC1"
                     /inference="alignment:Splign:2.1.0"
     exon            1616..1794
                     /gene="NCOR2"
                     /gene_synonym="CTG26; N-CoR2; SMAP270; SMRT; SMRTE;
                     SMRTE-tau; TNRC14; TRAC; TRAC-1; TRAC1"
                     /inference="alignment:Splign:2.1.0"
     exon            1795..1849
                     /gene="NCOR2"
                     /gene_synonym="CTG26; N-CoR2; SMAP270; SMRT; SMRTE;
                     SMRTE-tau; TNRC14; TRAC; TRAC-1; TRAC1"
                     /inference="alignment:Splign:2.1.0"
     exon            1850..1948
                     /gene="NCOR2"
                     /gene_synonym="CTG26; N-CoR2; SMAP270; SMRT; SMRTE;
                     SMRTE-tau; TNRC14; TRAC; TRAC-1; TRAC1"
                     /inference="alignment:Splign:2.1.0"
     exon            1949..2106
                     /gene="NCOR2"
                     /gene_synonym="CTG26; N-CoR2; SMAP270; SMRT; SMRTE;
                     SMRTE-tau; TNRC14; TRAC; TRAC-1; TRAC1"
                     /inference="alignment:Splign:2.1.0"
     exon            2107..2279
                     /gene="NCOR2"
                     /gene_synonym="CTG26; N-CoR2; SMAP270; SMRT; SMRTE;
                     SMRTE-tau; TNRC14; TRAC; TRAC-1; TRAC1"
                     /inference="alignment:Splign:2.1.0"
     exon            2280..2342
                     /gene="NCOR2"
                     /gene_synonym="CTG26; N-CoR2; SMAP270; SMRT; SMRTE;
                     SMRTE-tau; TNRC14; TRAC; TRAC-1; TRAC1"
                     /inference="alignment:Splign:2.1.0"
     exon            2343..2485
                     /gene="NCOR2"
                     /gene_synonym="CTG26; N-CoR2; SMAP270; SMRT; SMRTE;
                     SMRTE-tau; TNRC14; TRAC; TRAC-1; TRAC1"
                     /inference="alignment:Splign:2.1.0"
     exon            2486..2633
                     /gene="NCOR2"
                     /gene_synonym="CTG26; N-CoR2; SMAP270; SMRT; SMRTE;
                     SMRTE-tau; TNRC14; TRAC; TRAC-1; TRAC1"
                     /inference="alignment:Splign:2.1.0"
     exon            2634..3222
                     /gene="NCOR2"
                     /gene_synonym="CTG26; N-CoR2; SMAP270; SMRT; SMRTE;
                     SMRTE-tau; TNRC14; TRAC; TRAC-1; TRAC1"
                     /inference="alignment:Splign:2.1.0"
     exon            3223..3343
                     /gene="NCOR2"
                     /gene_synonym="CTG26; N-CoR2; SMAP270; SMRT; SMRTE;
                     SMRTE-tau; TNRC14; TRAC; TRAC-1; TRAC1"
                     /inference="alignment:Splign:2.1.0"
     exon            3344..3515
                     /gene="NCOR2"
                     /gene_synonym="CTG26; N-CoR2; SMAP270; SMRT; SMRTE;
                     SMRTE-tau; TNRC14; TRAC; TRAC-1; TRAC1"
                     /inference="alignment:Splign:2.1.0"
     exon            3516..3680
                     /gene="NCOR2"
                     /gene_synonym="CTG26; N-CoR2; SMAP270; SMRT; SMRTE;
                     SMRTE-tau; TNRC14; TRAC; TRAC-1; TRAC1"
                     /inference="alignment:Splign:2.1.0"
     exon            3681..3820
                     /gene="NCOR2"
                     /gene_synonym="CTG26; N-CoR2; SMAP270; SMRT; SMRTE;
                     SMRTE-tau; TNRC14; TRAC; TRAC-1; TRAC1"
                     /inference="alignment:Splign:2.1.0"
     exon            3821..3923
                     /gene="NCOR2"
                     /gene_synonym="CTG26; N-CoR2; SMAP270; SMRT; SMRTE;
                     SMRTE-tau; TNRC14; TRAC; TRAC-1; TRAC1"
                     /inference="alignment:Splign:2.1.0"
     exon            3924..4028
                     /gene="NCOR2"
                     /gene_synonym="CTG26; N-CoR2; SMAP270; SMRT; SMRTE;
                     SMRTE-tau; TNRC14; TRAC; TRAC-1; TRAC1"
                     /inference="alignment:Splign:2.1.0"
     exon            4029..4132
                     /gene="NCOR2"
                     /gene_synonym="CTG26; N-CoR2; SMAP270; SMRT; SMRTE;
                     SMRTE-tau; TNRC14; TRAC; TRAC-1; TRAC1"
                     /inference="alignment:Splign:2.1.0"
     exon            4133..4283
                     /gene="NCOR2"
                     /gene_synonym="CTG26; N-CoR2; SMAP270; SMRT; SMRTE;
                     SMRTE-tau; TNRC14; TRAC; TRAC-1; TRAC1"
                     /inference="alignment:Splign:2.1.0"
     exon            4284..4424
                     /gene="NCOR2"
                     /gene_synonym="CTG26; N-CoR2; SMAP270; SMRT; SMRTE;
                     SMRTE-tau; TNRC14; TRAC; TRAC-1; TRAC1"
                     /inference="alignment:Splign:2.1.0"
     exon            4425..4511
                     /gene="NCOR2"
                     /gene_synonym="CTG26; N-CoR2; SMAP270; SMRT; SMRTE;
                     SMRTE-tau; TNRC14; TRAC; TRAC-1; TRAC1"
                     /inference="alignment:Splign:2.1.0"
     exon            4512..4798
                     /gene="NCOR2"
                     /gene_synonym="CTG26; N-CoR2; SMAP270; SMRT; SMRTE;
                     SMRTE-tau; TNRC14; TRAC; TRAC-1; TRAC1"
                     /inference="alignment:Splign:2.1.0"
     exon            4799..5153
                     /gene="NCOR2"
                     /gene_synonym="CTG26; N-CoR2; SMAP270; SMRT; SMRTE;
                     SMRTE-tau; TNRC14; TRAC; TRAC-1; TRAC1"
                     /inference="alignment:Splign:2.1.0"
     exon            5154..5375
                     /gene="NCOR2"
                     /gene_synonym="CTG26; N-CoR2; SMAP270; SMRT; SMRTE;
                     SMRTE-tau; TNRC14; TRAC; TRAC-1; TRAC1"
                     /inference="alignment:Splign:2.1.0"
     exon            5376..5627
                     /gene="NCOR2"
                     /gene_synonym="CTG26; N-CoR2; SMAP270; SMRT; SMRTE;
                     SMRTE-tau; TNRC14; TRAC; TRAC-1; TRAC1"
                     /inference="alignment:Splign:2.1.0"
     exon            5628..5777
                     /gene="NCOR2"
                     /gene_synonym="CTG26; N-CoR2; SMAP270; SMRT; SMRTE;
                     SMRTE-tau; TNRC14; TRAC; TRAC-1; TRAC1"
                     /inference="alignment:Splign:2.1.0"
     exon            5778..5927
                     /gene="NCOR2"
                     /gene_synonym="CTG26; N-CoR2; SMAP270; SMRT; SMRTE;
                     SMRTE-tau; TNRC14; TRAC; TRAC-1; TRAC1"
                     /inference="alignment:Splign:2.1.0"
     exon            5928..6126
                     /gene="NCOR2"
                     /gene_synonym="CTG26; N-CoR2; SMAP270; SMRT; SMRTE;
                     SMRTE-tau; TNRC14; TRAC; TRAC-1; TRAC1"
                     /inference="alignment:Splign:2.1.0"
     exon            6127..6554
                     /gene="NCOR2"
                     /gene_synonym="CTG26; N-CoR2; SMAP270; SMRT; SMRTE;
                     SMRTE-tau; TNRC14; TRAC; TRAC-1; TRAC1"
                     /inference="alignment:Splign:2.1.0"
     exon            6555..6704
                     /gene="NCOR2"
                     /gene_synonym="CTG26; N-CoR2; SMAP270; SMRT; SMRTE;
                     SMRTE-tau; TNRC14; TRAC; TRAC-1; TRAC1"
                     /inference="alignment:Splign:2.1.0"
     exon            6705..6850
                     /gene="NCOR2"
                     /gene_synonym="CTG26; N-CoR2; SMAP270; SMRT; SMRTE;
                     SMRTE-tau; TNRC14; TRAC; TRAC-1; TRAC1"
                     /inference="alignment:Splign:2.1.0"
     exon            6851..7044
                     /gene="NCOR2"
                     /gene_synonym="CTG26; N-CoR2; SMAP270; SMRT; SMRTE;
                     SMRTE-tau; TNRC14; TRAC; TRAC-1; TRAC1"
                     /inference="alignment:Splign:2.1.0"
     exon            7045..7194
                     /gene="NCOR2"
                     /gene_synonym="CTG26; N-CoR2; SMAP270; SMRT; SMRTE;
                     SMRTE-tau; TNRC14; TRAC; TRAC-1; TRAC1"
                     /inference="alignment:Splign:2.1.0"
     exon            7195..7343
                     /gene="NCOR2"
                     /gene_synonym="CTG26; N-CoR2; SMAP270; SMRT; SMRTE;
                     SMRTE-tau; TNRC14; TRAC; TRAC-1; TRAC1"
                     /inference="alignment:Splign:2.1.0"
     exon            7344..7397
                     /gene="NCOR2"
                     /gene_synonym="CTG26; N-CoR2; SMAP270; SMRT; SMRTE;
                     SMRTE-tau; TNRC14; TRAC; TRAC-1; TRAC1"
                     /inference="alignment:Splign:2.1.0"
     exon            7398..7622
                     /gene="NCOR2"
                     /gene_synonym="CTG26; N-CoR2; SMAP270; SMRT; SMRTE;
                     SMRTE-tau; TNRC14; TRAC; TRAC-1; TRAC1"
                     /inference="alignment:Splign:2.1.0"
     exon            7623..7802
                     /gene="NCOR2"
                     /gene_synonym="CTG26; N-CoR2; SMAP270; SMRT; SMRTE;
                     SMRTE-tau; TNRC14; TRAC; TRAC-1; TRAC1"
                     /inference="alignment:Splign:2.1.0"
     exon            7803..8971
                     /gene="NCOR2"
                     /gene_synonym="CTG26; N-CoR2; SMAP270; SMRT; SMRTE;
                     SMRTE-tau; TNRC14; TRAC; TRAC-1; TRAC1"
                     /inference="alignment:Splign:2.1.0"
     regulatory      8949..8954
                     /regulatory_class="polyA_signal_sequence"
                     /gene="NCOR2"
                     /gene_synonym="CTG26; N-CoR2; SMAP270; SMRT; SMRTE;
                     SMRTE-tau; TNRC14; TRAC; TRAC-1; TRAC1"
                     /note="hexamer: ATTAAA"
     polyA_site      8971
                     /gene="NCOR2"
                     /gene_synonym="CTG26; N-CoR2; SMAP270; SMRT; SMRTE;
                     SMRTE-tau; TNRC14; TRAC; TRAC-1; TRAC1"
                     /note="major polyA site"
ORIGIN      
        1 gccaccgccg ccgcggccgc cggggagcgc ggagccgcgg gcaggccggg ccgcaccgga
       61 gccccgcgtc cgccggcgcc ccgcccgagc cctgcgcccg cgccctgcgc tccgcgatgc
      121 gcgccaactt gcgggccggg gacccagggc cggcgcccta ggaggcggcg gcgggaggat
      181 cgcgtcccga cccgaggccg ggcctgctgc gcgcccccag cccgatcggc accgccactt
      241 gcctgagcgc cccggcggcc cgagcgcgcc ccaagcccgg gcgccaccgc tgccacctcc
      301 gcgaggtctc cctgagtctt tgaggacaca gcctcgctgg aggcagtttc tggtgccagt
      361 gacggggtgg cccgtgagct gatgacgagg actggctttt aatccttggt ggtgattaag
      421 agaaagctta ttggggcctg ggagcagctc cccgccgacc cccaccacca tgtcgggatc
      481 cacacagcct gtggcacaga cgtggagggc cactgagccc cgctacccgc cccacagcct
      541 ttcctaccca gtgcagatcg cccggacgca cacggacgtc gggctcctgg agtaccagca
      601 ccactcccgc gactatgcct cccacctgtc gcccggctcc atcatccagc cccagcggcg
      661 gaggccctcc ctgctgtctg agttccagcc cgggaatgaa cggtcccagg agctccacct
      721 gcggccagag tcccactcat acctgcccga gctggggaag tcagagatgg agttcattga
      781 aagcaagcgc cctcggctag agctgctgcc tgaccccctg ctgcgaccgt cacccctgct
      841 ggccacgggc cagcctgcgg gatctgaaga cctcaccaag gaccgtagcc tgacgggcaa
      901 gctggaaccg gtgtctcccc ccagcccccc gcacactgac cctgagctgg agctggtgcc
      961 gccacggctg tccaaggagg agctgatcca gaacatggac cgcgtggacc gagagatcac
     1021 catggtagag cagcagatct ctaagctgaa gaagaagcag caacagctgg aggaggaggc
     1081 tgccaagccg cccgagcctg agaagcccgt gtcaccgccg cccatcgagt cgaagcaccg
     1141 cagcctggtg cagatcatct acgacgagaa ccggaagaag gctgaagctg cacatcggat
     1201 tctggaaggc ctggggcccc aggtggagct gccgctgtac aaccagccct ccgacacccg
     1261 gcagtatcat gagaacatca aaataaacca ggcgatgcgg aagaagctaa tcttgtactt
     1321 caagaggagg aatcacgctc ggaaacaatg ggagcagaag ttctgccagc gctatgacca
     1381 gctcatggag gcctgggaga agaaggtgga gcgcatcgag aacaaccccc ggcggcgggc
     1441 caaggagagc aaggtgcgcg agtactacga gaagcagttc cctgagatcc gcaagcagcg
     1501 cgagctgcag gagcgcatgc agagggtggg ccagcggggc agtgggctgt ccatgtcggc
     1561 cgcccgcagc gagcacgagg tgtcagagat catcgatggc ctctcagagc aggagaacct
     1621 ggagaagcag atgcgccagc tggccgtgat cccgcccatg ctgtacgacg ctgaccagca
     1681 gcgcatcaag ttcatcaaca tgaacgggct tatggccgac cccatgaagg tgtacaaaga
     1741 ccgccaggtc atgaacatgt ggagtgagca ggagaaggag accttccggg agaagttcat
     1801 gcagcatccc aagaactttg gcctgatcgc atcattcctg gagaggaaga cagtggctga
     1861 gtgcgtcctc tattactacc tgactaagaa gaatgagaac tataagagcc tggtgagacg
     1921 gagctatcgg cgccgcggca agagccagca gcagcaacaa cagcagcagc agcagcagca
     1981 gcagcagcag cagcagccca tgccccgcag cagccaggag gagaaagatg agaaggagaa
     2041 ggaaaaggag gcggagaagg aggaggagaa gccggaggtg gagaacgaca aggaagacct
     2101 cctcaaggag aagacagacg acacctcagg ggaggacaac gacgagaagg aggctgtggc
     2161 ctccaaaggc cgcaaaactg ccaacagcca gggaagacgc aaaggccgca tcacccgctc
     2221 aatggctaat gaggccaaca gcgaggaggc catcaccccc cagcagagcg ccgagctggc
     2281 ctccatggag ctgaatgaga gttctcgctg gacagaagaa gaaatggaaa cagccaagaa
     2341 aggtctcctg gaacacggcc gcaactggtc ggccatcgcc cggatggtgg gctccaagac
     2401 tgtgtcgcag tgtaagaact tctacttcaa ctacaagaag aggcagaacc tcgatgagat
     2461 cttgcagcag cacaagctga agatggagaa ggagaggaac gcgcggagga agaagaagaa
     2521 agcgccggcg gcggccagcg aggaggctgc attcccgccc gtggtggagg atgaggagat
     2581 ggaggcgtcg ggcgtgagcg gaaatgagga ggagatggtg gaggaggctg aagccactgt
     2641 caacaacagc tcagacaccg agagcatccc ctctcctcac actgaggccg ccaaggacac
     2701 agggcagaat gggcccaagc ccccagccac cctgggcgcc gacgggccac ccccagggcc
     2761 acccacccca ccaccggagg acatcccggc ccccactgag cccaccccgg cctctgaagc
     2821 caccggagcc cctacgcccc caccagcacc cccatcgccc tctgcacctc ctcctgtggt
     2881 ccccaaggag gagaaggagg aggagaccgc agcagcgccc ccagtggagg agggggagga
     2941 gcagaagccc cccgcggctg aggagctggc agtggacaca gggaaggccg aggagcccgt
     3001 caagagcgag tgcacggagg aagccgagga ggggccggcc aagggcaagg acgcggaggc
     3061 cgctgaggcc acggccgagg gggcgctcaa ggcagagaag aaggagggcg ggagcggcag
     3121 ggccaccaca gccaagagct cgggcgcccc ccaggacagc gactccagtg ctacctgcag
     3181 tgcagacgag gtggatgagg ccgagggcgg cgacaagaac cggctgctgt ccccaaggcc
     3241 cagcctcctc accccgactg gcgacccccg ggccaatgcc tcaccccaga agccactgga
     3301 cctgaagcag ctgaagcagc gagcggctgc catccccccc atccaggtca ccaaagtcca
     3361 tgagcccccc cgggaggacg cagctcccac caagccagct cccccagccc caccgccacc
     3421 gcaaaacctg cagccggaga gcgacgcccc tcagcagcct ggcagcagcc cccggggcaa
     3481 gagcaggagc ccggcacccc ccgccgacaa ggaggcagag aagcctgtgt tcttcccagc
     3541 cttcgcagcc gaggcccaga agctgcctgg ggacccccct tgctggactt ccggcctgcc
     3601 cttccccgtg cccccccgtg aggtgatcaa ggcctccccg catgccccgg acccctcagc
     3661 cttctcctac gctccacctg gtcacccact gcccctgggc ctccatgaca ctgcccggcc
     3721 cgtcctgccg cgcccaccca ccatctccaa cccgcctccc ctcatctcct ctgccaagca
     3781 ccccagcgtc ctcgagaggc aaataggtgc catctcccaa ggaatgtcgg tccagctcca
     3841 cgtcccgtac tcagagcatg ccaaggcccc ggtgggccct gtcaccatgg ggctgcccct
     3901 gcccatggac cccaaaaagc tggcaccctt cagcggagtg aagcaggagc agctgtcccc
     3961 acggggccag gctgggccac cggagagcct gggggtgccc acagcccagg aggcgtccgt
     4021 gctgagaggg acagctctgg gctcagttcc gggcggaagc atcaccaaag gcattcccag
     4081 cacacgggtg ccctcggaca gcgccatcac ataccgcggc tccatcaccc acggcacgcc
     4141 agctgacgtc ctgtacaagg gcaccatcac caggatcatc ggcgaggaca gcccgagtcg
     4201 cttggaccgc ggccgggagg acagcctgcc caagggccac gtcatctacg aaggcaagaa
     4261 gggccacgtc ttgtcctatg agggtggcat gtctgtgacc cagtgctcca aggaggacgg
     4321 cagaagcagc tcaggacccc cccatgagac ggccgccccc aagcgcacct atgacatgat
     4381 ggagggccgc gtgggcagag ccatctcctc agccagcatc gaaggtctca tgggccgtgc
     4441 catcccgccg gagcgacaca gcccccacca cctcaaagag cagcaccaca tccgcgggtc
     4501 catcacacaa gggatccctc ggtcctacgt ggaggcacag gaggactacc tgcgtcggga
     4561 ggccaagctc ctaaagcggg agggcacgcc tccgccccca ccgccctcac gggacctgac
     4621 cgaggcctac aagacgcagg ccctgggccc cctgaagctg aagccggccc atgagggcct
     4681 ggtggccacg gtgaaggagg cgggccgctc catccatgag atcccgcgcg aggagctgcg
     4741 gcacacgccc gagctgcccc tggccccgcg gccgctcaag gagggctcca tcacgcaggg
     4801 caccccgctc aagtacgaca ccggcgcgtc caccactggc tccaaaaagc acgacgtacg
     4861 ctccctcatc ggcagccccg gccggacgtt cccacccgtg cacccgctgg atgtgatggc
     4921 cgacgcccgg gcactggaac gtgcctgcta cgaggagagc ctgaagagcc ggccagggac
     4981 cgccagcagc tcggggggct ccattgcgcg cggcgccccg gtcattgtgc ctgagctggg
     5041 taagccgcgg cagagccccc tgacctatga ggaccacggg gcaccctttg ccggccacct
     5101 cccacgaggt tcgcccgtga ccacgcggga gcccacgccg cgcctgcagg agggcagcct
     5161 ttcgtccagc aaggcatccc aggaccgaaa gctgacgtcg acgcctcgtg agatcgccaa
     5221 gtccccgcac agcaccgtgc ccgagcacca cccacacccc atctcgccct atgagcacct
     5281 gcttcggggc gtgagtggcg tggacctgta tcgcagccac atccccctgg ccttcgaccc
     5341 cacctccata ccccgcggca tccctctgga cgcagccgct gcctactacc tgccccgaca
     5401 cctggccccc aaccccacct acccgcacct gtacccaccc tacctcatcc gcggctaccc
     5461 cgacacggcg gcgctggaga accggcagac catcatcaat gactacatca cctcgcagca
     5521 gatgcaccac aacgcggcca ccgccatggc ccagcgagct gatatgctga ggggcctctc
     5581 gccccgcgag tcctcgctgg cactcaacta cgctgcgggt ccccgaggca tcatcgacct
     5641 gtcccaagtg ccacacctgc ctgtgctcgt gcccccgaca ccaggcaccc cagccaccgc
     5701 catggaccgc cttgcctacc tccccaccgc gccccagccc ttcagcagcc gccacagcag
     5761 ctccccactc tccccaggag gtccaacaca cttgacaaaa ccaaccacca cgtcctcgtc
     5821 cgagcgggag cgagaccggg atcgagagcg ggaccgggat cgggagcggg aaaagtccat
     5881 cctcacgtcc accacgacgg tggagcacgc acccatctgg agacctggta cagagcagag
     5941 cagcggcagc agcggcgggg gtgggggcag cagcagccgc cccgcctccc actcccatgc
     6001 ccaccagcac tcgcccatct cccctcggac ccaggatgcc ctccagcaga gacccagtgt
     6061 gcttcacaac acaggcatga agggtatcat caccgctgtg gagcccagca cgcccacggt
     6121 cctgaggtcc acctccacct cctcacccgt tcgcccggct gccacattcc cacctgccac
     6181 ccactgccca ctgggcggca ccctcgatgg ggtctaccct accctcatgg agcccgtctt
     6241 gctgcccaag gaggcccccc gggtcgcccg gccagagcgg ccccgagcag acaccggcca
     6301 tgccttcctc gccaagcccc cagcccgctc cgggctggag cccgcctcct cccccagcaa
     6361 gggctcggag ccccggcccc tagtgcctcc tgtctctggc cacgccacca tcgcccgcac
     6421 ccctgcgaag aacctcgcac ctcaccacgc cagcccggac ccgccggcgc cacctgcctc
     6481 ggcctcggac ccgcaccggg aaaagactca aagtaaaccc ttttccatcc aggaactgga
     6541 actccgttct ctgggttacc acggcagcag ctacagcccc gaaggggtgg agcccgtcag
     6601 ccctgtgagc tcacccagtc tgacccacga caaggggctc cccaagcacc tggaagagct
     6661 cgacaagagc cacctggagg gggagctgcg gcccaagcag ccaggccccg tgaagcttgg
     6721 cggggaggcc gcccacctcc cacacctgcg gccgctgcct gagagccagc cctcgtccag
     6781 cccgctgctc cagaccgccc caggggtcaa aggtcaccag cgggtggtca ccctggccca
     6841 gcacatcagt gaggtcatca cacaggacta cacccggcac cacccacagc agctcagcgc
     6901 acccctgccc gcccccctct actccttccc tggggccagc tgccccgtcc tggacctccg
     6961 ccgcccaccc agtgacctct acctcccgcc cccggaccat ggtgccccgg cccgtggctc
     7021 cccccacagc gaagggggca agaggtctcc agagccaaac aagacgtcgg tcttgggtgg
     7081 tggtgaggac ggtattgaac ctgtgtcccc accggagggc atgacggagc cagggcactc
     7141 ccggagtgct gtgtacccgc tgctgtaccg ggatggggaa cagacggagc ccagcaggat
     7201 gggctccaag tctccaggca acaccagcca gccgccagcc ttcttcagca agctgaccga
     7261 gagcaactcc gccatggtca agtccaagaa gcaagagatc aacaagaagc tgaacaccca
     7321 caaccggaat gagcctgaat acaatatcag ccagcctggg acggagatct tcaatatgcc
     7381 cgccatcacc ggaacaggcc ttatgaccta tagaagccag gcggtgcagg aacatgccag
     7441 caccaacatg gggctggagg ccataattag aaaggcactc atgggtaaat atgaccagtg
     7501 ggaagagtcc ccgccgctca gcgccaatgc ttttaaccct ctgaatgcca gtgccagcct
     7561 gcccgctgct atgcccataa ccgctgctga cggacggagt gaccacacac tcacctcgcc
     7621 aggtggcggc gggaaggcca aggtctctgg cagacccagc agccgaaaag ccaagtcccc
     7681 ggccccgggc ctggcatctg gggaccggcc accctctgtc tcctcagtgc actcggaggg
     7741 agactgcaac cgccggacgc cgctcaccaa ccgcgtgtgg gaggacaggc cctcgtccgc
     7801 aggttccacg ccattcccct acaaccccct gatcatgcgg ctgcaggcgg gtgtcatggc
     7861 ttccccaccc ccaccgggcc tccccgcggg cagcgggccc ctcgctggcc cccaccacgc
     7921 ctgggacgag gagcccaagc cactgctctg ctcgcagtac gagacactct ccgacagcga
     7981 gtgactcaga acagggcggg ggggggggcg gtgtcaggtc ccagcgagcc acaggaacgg
     8041 ccctgcagga gcagggcggc tgccgactcc cccaaccaag gaaggagccc ctgagtccgc
     8101 ctgcgcctcc atccatctgt ccgtccagag ccggcatcct tgcctgtcta aagccttaac
     8161 taagactccc gccccgggct ggccctgtgc agaccttact caggggatgt ttacctggtg
     8221 ctcgggaagg gaggggaagg ggccggggag ggggcacggc aggcgtgtgg cagccacacg
     8281 caggcggcca gggcggccag ggacccaaag caggatgacc acgcacctcc acgccactgc
     8341 ctcccccgaa tgcatttgga accaaagtct aaactgagct cgcagccccc gcgccctccc
     8401 tccgcctccc atcccgctta gcgctctgga cagatggacg caggccctgt ccagccccca
     8461 gtgcgctcgt tccggtcccc acagactgcc ccagccaacg agattgctgg aaaccaagtc
     8521 aggccaggtg ggcggacaaa agggccaggt gcggcctggg gggaacggat gctccgagga
     8581 ctggactgtt tttttcacac atcgttgccg cagcggtggg aaggaaaggc agatgtaaat
     8641 gatgtgttgg tttacagggt atatttttga taccttcaat gaattaattc agatgtttta
     8701 cgcaaggaag gacttaccca gtattactgc tgctgtgctt ttgatctctg cttaccgttc
     8761 aagaggcgtg tgcaggccga cagtcggtga ccccatcact cgcaggacca agggggcggg
     8821 gactgctggc tcacgccccg ctgtgtcctc cctccctccc ttccttgggc agaatgaatt
     8881 cgatgcgtat tctgtggccg ccatctgcgc agggtggtgg tattctgtca tttacacacg
     8941 tcgttctaat taaaaagcga attatactcc a
//
