LOCUS       NM_006311              10705 bp    mRNA    linear   PRI 11-SEP-2024
DEFINITION  Homo sapiens nuclear receptor corepressor 1 (NCOR1), transcript
            variant 1, mRNA.
ACCESSION   NM_006311 XM_001133522
VERSION     NM_006311.4
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 10705)
  AUTHORS   Lu,Y., Ma,W.B., Ren,G.M., Li,Y.T., Wang,T., Zhan,Y.Q., Xiang,S.S.,
            Chen,H., Gao,H.Y., Zhao,K., Yu,M., Li,C.Y., Yang,X.M. and Yin,R.H.
  TITLE     GPS2 promotes erythroid differentiation in K562 erythroleukemia
            cells primarily via NCOR1
  JOURNAL   Int J Hematol 120 (2), 157-166 (2024)
   PUBMED   38814500
  REMARK    GeneRIF: GPS2 promotes erythroid differentiation in K562
            erythroleukemia cells primarily via NCOR1.
REFERENCE   2  (bases 1 to 10705)
  AUTHORS   Teichmann,T., Malacarne,P., Zehr,S., Gunther,S., Pfluger-Muller,B.,
            Warwick,T. and Brandes,R.P.
  TITLE     NCoR1 limits angiogenic capacity by altering Notch signaling
  JOURNAL   J Mol Cell Cardiol 188, 65-78 (2024)
   PUBMED   38359551
  REMARK    GeneRIF: NCoR1 limits angiogenic capacity by altering Notch
            signaling.
REFERENCE   3  (bases 1 to 10705)
  AUTHORS   Mansoor,A., Akhter,A., Hamidi,M., Roshan,T.M., Shabani-Rad,M.T. and
            Stewart,D.
  TITLE     Exploring TBL1XR1 and NCOR1 Expression in B-cell Lymphoma Subtypes:
            Interaction With DNA Damage Repair Genes
  JOURNAL   Anticancer Res 43 (11), 4801-4807 (2023)
   PUBMED   37909960
  REMARK    GeneRIF: Exploring TBL1XR1 and NCOR1 Expression in B-cell Lymphoma
            Subtypes: Interaction With DNA Damage Repair Genes.
REFERENCE   4  (bases 1 to 10705)
  AUTHORS   Torres,H.M., Yeo,D. and Westendorf,J.J.
  TITLE     Pulling rank with RNA: RANKL promotes the association of
            PGC-1beta/RNA complexes with NCoR/HDAC3 to activate gene expression
            in osteoclasts
  JOURNAL   Mol Cell 83 (19), 3397-3399 (2023)
   PUBMED   37802020
  REMARK    GeneRIF: Pulling rank with RNA: RANKL promotes the association of
            PGC-1beta/RNA complexes with NCoR/HDAC3 to activate gene expression
            in osteoclasts.
REFERENCE   5  (bases 1 to 10705)
  AUTHORS   Nagaya,T., Chen,K.S., Fujieda,M., Ohmori,S., Richer,J.K.,
            Horwitz,K.B., Lupski,J.R. and Seo,H.
  TITLE     Localization of the human nuclear receptor corepressor (hN-CoR)
            gene between the CMT1A and the SMS critical regions of chromosome
            17p11.2
  JOURNAL   Genomics 59 (3), 339-341 (1999)
   PUBMED   10444336
REFERENCE   6  (bases 1 to 10705)
  AUTHORS   Wang,J., Hoshino,T., Redner,R.L., Kajigaya,S. and Liu,J.M.
  TITLE     ETO, fusion partner in t(8;21) acute myeloid leukemia, represses
            transcription by interaction with the human N-CoR/mSin3/HDAC1
            complex
  JOURNAL   Proc Natl Acad Sci U S A 95 (18), 10860-10865 (1998)
   PUBMED   9724795
  REMARK    GeneRIF: This paper describes the cloning of the full-length human
            NCOR1 cDNA.
REFERENCE   7  (bases 1 to 10705)
  AUTHORS   Zamir,I., Dawson,J., Lavinsky,R.M., Glass,C.K., Rosenfeld,M.G. and
            Lazar,M.A.
  TITLE     Cloning and characterization of a corepressor and potential
            component of the nuclear hormone receptor repression complex
  JOURNAL   Proc Natl Acad Sci U S A 94 (26), 14400-14405 (1997)
   PUBMED   9405624
REFERENCE   8  (bases 1 to 10705)
  AUTHORS   Harding,H.P., Atkins,G.B., Jaffe,A.B., Seo,W.J. and Lazar,M.A.
  TITLE     Transcriptional activation and repression by RORalpha, an orphan
            nuclear receptor required for cerebellar development
  JOURNAL   Mol Endocrinol 11 (11), 1737-1746 (1997)
   PUBMED   9328355
REFERENCE   9  (bases 1 to 10705)
  AUTHORS   Tagami,T., Madison,L.D., Nagaya,T. and Jameson,J.L.
  TITLE     Nuclear receptor corepressors activate rather than suppress basal
            transcription of genes that are negatively regulated by thyroid
            hormone
  JOURNAL   Mol Cell Biol 17 (5), 2642-2648 (1997)
   PUBMED   9111334
REFERENCE   10 (bases 1 to 10705)
  AUTHORS   Downes,M., Burke,L.J., Bailey,P.J. and Muscat,G.E.
  TITLE     Two receptor interaction domains in the corepressor, N-CoR/RIP13,
            are required for an efficient interaction with Rev-erbA alpha and
            RVR: physical association is dependent on the E region of the
            orphan receptors
  JOURNAL   Nucleic Acids Res 24 (22), 4379-4386 (1996)
   PUBMED   8948627
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from BJ995810.1, AF044209.1,
            AC002553.2 and AW015698.1.
            This sequence is a reference standard in the RefSeqGene project.
            
            On Nov 23, 2018 this sequence version replaced NM_006311.3.
            
            Summary: This gene encodes a protein that mediates
            ligand-independent transcription repression of thyroid-hormone and
            retinoic-acid receptors by promoting chromatin condensation and
            preventing access of the transcription machinery. It is part of a
            complex which also includes histone deacetylases and
            transcriptional regulators similar to the yeast protein Sin3p. This
            gene is located between the Charcot-Marie-Tooth and Smith-Magenis
            syndrome critical regions on chromosome 17. Alternate splicing
            results in multiple transcript variants. Pseudogenes of this gene
            are found on chromosomes 17 and 20.[provided by RefSeq, Jun 2010].
            
            Transcript Variant: This variant (1) represents the longest
            transcript and encodes the longest isoform (1).
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AF044209.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA1965299,
                                           SAMEA1966682 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000268712.8/ ENSP00000268712.2
            RefSeq Select criteria :: based on conservation
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-4                 BJ995810.1         27-30
            5-3282              AF044209.1         2-3279
            3283-3283           AC002553.2         82990-82990
            3284-3491           AF044209.1         3281-3488
            3492-3492           AC002553.2         88753-88753
            3493-4764           AF044209.1         3490-4761
            4765-4944           AC002553.2         101296-101475
            4945-6674           AF044209.1         4942-6671
            6675-6675           AC002553.2         120460-120460
            6676-7918           AF044209.1         6673-7915
            7919-9369           AC002553.2         137466-138916
            9370-9768           AW015698.1         16-414              c
            9769-10705          AC002553.2         139316-140252
FEATURES             Location/Qualifiers
     source          1..10705
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="17"
                     /map="17p12-p11.2"
     gene            1..10705
                     /gene="NCOR1"
                     /gene_synonym="hN-CoR; N-CoR; N-CoR1; PPP1R109; TRAC1"
                     /note="nuclear receptor corepressor 1"
                     /db_xref="GeneID:9611"
                     /db_xref="HGNC:HGNC:7672"
                     /db_xref="MIM:600849"
     exon            1..173
                     /gene="NCOR1"
                     /gene_synonym="hN-CoR; N-CoR; N-CoR1; PPP1R109; TRAC1"
                     /inference="alignment:Splign:2.1.0"
     exon            174..351
                     /gene="NCOR1"
                     /gene_synonym="hN-CoR; N-CoR; N-CoR1; PPP1R109; TRAC1"
                     /inference="alignment:Splign:2.1.0"
     CDS             244..7566
                     /gene="NCOR1"
                     /gene_synonym="hN-CoR; N-CoR; N-CoR1; PPP1R109; TRAC1"
                     /note="isoform 1 is encoded by transcript variant 1;
                     thyroid hormone- and retinoic acid receptor-associated
                     corepressor 1; protein phosphatase 1, regulatory subunit
                     109"
                     /codon_start=1
                     /product="nuclear receptor corepressor 1 isoform 1"
                     /protein_id="NP_006302.2"
                     /db_xref="CCDS:CCDS11175.1"
                     /db_xref="GeneID:9611"
                     /db_xref="HGNC:HGNC:7672"
                     /db_xref="MIM:600849"
                     /translation="MSSSGYPPNQGAFSTEQSRYPPHSVQYTFPNTRHQQEFAVPDYR
                     SSHLEVSQASQLLQQQQQQQLRRRPSLLSEFHPGSDRPQERRTSYEPFHPGPSPVDHD
                     SLESKRPRLEQVSDSHFQRVSAAVLPLVHPLPEGLRASADAKKDPAFGGKHEAPSSPI
                     SGQPCGDDQNASPSKLSKEELIQSMDRVDREIAKVEQQILKLKKKQQQLEEEAAKPPE
                     PEKPVSPPPVEQKHRSIVQIIYDENRKKAEEAHKIFEGLGPKVELPLYNQPSDTKVYH
                     ENIKTNQVMRKKLILFFKRRNHARKQREQKICQRYDQLMEAWEKKVDRIENNPRRKAK
                     ESKTREYYEKQFPEIRKQREQQERFQRVGQRGAGLSATIARSEHEISEIIDGLSEQEN
                     NEKQMRQLSVIPPMMFDAEQRRVKFINMNGLMEDPMKVYKDRQFMNVWTDHEKEIFKD
                     KFIQHPKNFGLIASYLERKSVPDCVLYYYLTKKNENYKALVRRNYGKRRGRNQQIARP
                     SQEEKVEEKEEDKAEKTEKKEEEKKDEEEKDEKEDSKENTKEKDKIDGTAEETEEREQ
                     ATPRGRKTANSQGRRKGRITRSMTNEAAAASAAAAAATEEPPPPLPPPPEPISTEPVE
                     TSRWTEEEMEVAKKGLVEHGRNWAAIAKMVGTKSEAQCKNFYFNYKRRHNLDNLLQQH
                     KQKTSRKPREERDVSQCESVASTVSAQEDEDIEASNEEENPEDSEVEAVKPSEDSPEN
                     ATSRGNTEPAVELEPTTETAPSTSPSLAVPSTKPAEDESVETQVNDSISAETAEQMDV
                     DQQEHSAEEGSVCDPPPATKADSVDVEVRVPENHASKVEGDNTKERDLDRASEKVEPR
                     DEDLVVAQQINAQRPEPQSDNDSSATCSADEDVDGEPERQRMFPMDSKPSLLNPTGSI
                     LVSSPLKPNPLDLPQLQHRAAVIPPMVSCTPCNIPIGTPVSGYALYQRHIKAMHESAL
                     LEEQRQRQEQIDLECRSSTSPCGTSKSPNREWEVLQPAPHQVITNLPEGVRLPTTRPT
                     RPPPPLIPSSKTTVASEKPSFIMGGSISQGTPGTYLTSHNQASYTQETPKPSVGSISL
                     GLPRQQESAKSATLPYIKQEEFSPRSQNSQPEGLLVRAQHEGVVRGTAGAIQEGSITR
                     GTPTSKISVESIPSLRGSITQGTPALPQTGIPTEALVKGSISRMPIEDSSPEKGREEA
                     ASKGHVIYEGKSGHILSYDNIKNAREGTRSPRTAHEISLKRSYESVEGNIKQGMSMRE
                     SPVSAPLEGLICRALPRGSPHSDLKERTVLSGSIMQGTPRATTESFEDGLKYPKQIKR
                     ESPPIRAFEGAITKGKPYDGITTIKEMGRSIHEIPRQDILTQESRKTPEVVQSTRPII
                     EGSISQGTPIKFDNNSGQSAIKHNVKSLITGPSKLSRGMPPLEIVPENIKVVERGKYE
                     DVKAGETVRSRHTSVVSSGPSVLRSTLHEAPKAQLSPGIYDDTSARRTPVSYQNTMSR
                     GSPMMNRTSDVTISSNKSTNHERKSTLTPTQRESIPAKSPVPGVDPVVSHSPFDPHHR
                     GSTAGEVYRSHLPTHLDPAMPFHRALDPAAAAYLFQRQLSPTPGYPSQYQLYAMENTR
                     QTILNDYITSQQMQVNLRPDVARGLSPREQPLGLPYPATRGIIDLTNMPPTILVPHPG
                     GTSTPPMDRITYIPGTQITFPPRPYNSASMSPGHPTHLAAAASAEREREREREKERER
                     ERIAAASSDLYLRPGSEQPGRPGSHGYVRSPSPSVRTQETMLQQRPSVFQGTNGTSVI
                     TPLDPTAQLRIMPLPAGGPSISQGLPASRYNTAADALAALVDAAASAPQMDVSKTKES
                     KHEAARLEENLRSRSAAVSEQQQLEQKTLEVEKRSVQCLYTSSAFPSGKPQPHSSVVY
                     SEAGKDKGPPPKSRYEEELRTRGKTTITAANFIDVIITRQIASDKDARERGSQSSDSS
                     SSLSSHRYETPSDAIEVISPASSPAPPQEKLQTYQPEVVKANQAENDPTRQYEGPLHH
                     YRPQQESPSPQQQLPPSSQAEGMGQVPRTHRLITLADHICQIITQDFARNQVSSQTPQ
                     QPPTSTFQNSPSALVSTPVRTKTSNRYSPESQAQSVHHQRPGSRVSPENLVDKSRGSR
                     PGKSPERSHVSSEPYEPISPPQVPVVHEKQDSLLLLSQRGAEPAEQRNDARSPGSISY
                     LPSFFTKLENTSPMVKSKKQEIFRKLNSSGGGDSDMAAAQPGTEIFNLPAVTTSGSVS
                     SRGHSFADPASNLGLEDIIRKALMGSFDDKVEDHGVVMSQPMGVVPGTANTSVVTSGE
                     TRREEGDPSPHSGGVCKPKLISKSNSRKSKSPIPGQGYLGTERPSSVSSVHSEGDYHR
                     QTPGWAWEDRPSSTGSTQFPYNPLTMRMLSSTPPTPIACAPSAVNQAAPHQQNRIWER
                     EPAPLLSAQYETLSDSDD"
     exon            352..485
                     /gene="NCOR1"
                     /gene_synonym="hN-CoR; N-CoR; N-CoR1; PPP1R109; TRAC1"
                     /inference="alignment:Splign:2.1.0"
     exon            486..678
                     /gene="NCOR1"
                     /gene_synonym="hN-CoR; N-CoR; N-CoR1; PPP1R109; TRAC1"
                     /inference="alignment:Splign:2.1.0"
     exon            679..861
                     /gene="NCOR1"
                     /gene_synonym="hN-CoR; N-CoR; N-CoR1; PPP1R109; TRAC1"
                     /inference="alignment:Splign:2.1.0"
     exon            862..975
                     /gene="NCOR1"
                     /gene_synonym="hN-CoR; N-CoR; N-CoR1; PPP1R109; TRAC1"
                     /inference="alignment:Splign:2.1.0"
     exon            976..1032
                     /gene="NCOR1"
                     /gene_synonym="hN-CoR; N-CoR; N-CoR1; PPP1R109; TRAC1"
                     /inference="alignment:Splign:2.1.0"
     exon            1033..1085
                     /gene="NCOR1"
                     /gene_synonym="hN-CoR; N-CoR; N-CoR1; PPP1R109; TRAC1"
                     /inference="alignment:Splign:2.1.0"
     exon            1086..1152
                     /gene="NCOR1"
                     /gene_synonym="hN-CoR; N-CoR; N-CoR1; PPP1R109; TRAC1"
                     /inference="alignment:Splign:2.1.0"
     exon            1153..1325
                     /gene="NCOR1"
                     /gene_synonym="hN-CoR; N-CoR; N-CoR1; PPP1R109; TRAC1"
                     /inference="alignment:Splign:2.1.0"
     exon            1326..1416
                     /gene="NCOR1"
                     /gene_synonym="hN-CoR; N-CoR; N-CoR1; PPP1R109; TRAC1"
                     /inference="alignment:Splign:2.1.0"
     exon            1417..1595
                     /gene="NCOR1"
                     /gene_synonym="hN-CoR; N-CoR; N-CoR1; PPP1R109; TRAC1"
                     /inference="alignment:Splign:2.1.0"
     exon            1596..1650
                     /gene="NCOR1"
                     /gene_synonym="hN-CoR; N-CoR; N-CoR1; PPP1R109; TRAC1"
                     /inference="alignment:Splign:2.1.0"
     exon            1651..1752
                     /gene="NCOR1"
                     /gene_synonym="hN-CoR; N-CoR; N-CoR1; PPP1R109; TRAC1"
                     /inference="alignment:Splign:2.1.0"
     exon            1753..1877
                     /gene="NCOR1"
                     /gene_synonym="hN-CoR; N-CoR; N-CoR1; PPP1R109; TRAC1"
                     /inference="alignment:Splign:2.1.0"
     exon            1878..2095
                     /gene="NCOR1"
                     /gene_synonym="hN-CoR; N-CoR; N-CoR1; PPP1R109; TRAC1"
                     /inference="alignment:Splign:2.1.0"
     exon            2096..2158
                     /gene="NCOR1"
                     /gene_synonym="hN-CoR; N-CoR; N-CoR1; PPP1R109; TRAC1"
                     /inference="alignment:Splign:2.1.0"
     exon            2159..2298
                     /gene="NCOR1"
                     /gene_synonym="hN-CoR; N-CoR; N-CoR1; PPP1R109; TRAC1"
                     /inference="alignment:Splign:2.1.0"
     exon            2299..2425
                     /gene="NCOR1"
                     /gene_synonym="hN-CoR; N-CoR; N-CoR1; PPP1R109; TRAC1"
                     /inference="alignment:Splign:2.1.0"
     exon            2426..2933
                     /gene="NCOR1"
                     /gene_synonym="hN-CoR; N-CoR; N-CoR1; PPP1R109; TRAC1"
                     /inference="alignment:Splign:2.1.0"
     exon            2934..3063
                     /gene="NCOR1"
                     /gene_synonym="hN-CoR; N-CoR; N-CoR1; PPP1R109; TRAC1"
                     /inference="alignment:Splign:2.1.0"
     exon            3064..3259
                     /gene="NCOR1"
                     /gene_synonym="hN-CoR; N-CoR; N-CoR1; PPP1R109; TRAC1"
                     /inference="alignment:Splign:2.1.0"
     exon            3260..3420
                     /gene="NCOR1"
                     /gene_synonym="hN-CoR; N-CoR; N-CoR1; PPP1R109; TRAC1"
                     /inference="alignment:Splign:2.1.0"
     exon            3421..3541
                     /gene="NCOR1"
                     /gene_synonym="hN-CoR; N-CoR; N-CoR1; PPP1R109; TRAC1"
                     /inference="alignment:Splign:2.1.0"
     exon            3542..3643
                     /gene="NCOR1"
                     /gene_synonym="hN-CoR; N-CoR; N-CoR1; PPP1R109; TRAC1"
                     /inference="alignment:Splign:2.1.0"
     exon            3644..3744
                     /gene="NCOR1"
                     /gene_synonym="hN-CoR; N-CoR; N-CoR1; PPP1R109; TRAC1"
                     /inference="alignment:Splign:2.1.0"
     exon            3745..3913
                     /gene="NCOR1"
                     /gene_synonym="hN-CoR; N-CoR; N-CoR1; PPP1R109; TRAC1"
                     /inference="alignment:Splign:2.1.0"
     exon            3914..4054
                     /gene="NCOR1"
                     /gene_synonym="hN-CoR; N-CoR; N-CoR1; PPP1R109; TRAC1"
                     /inference="alignment:Splign:2.1.0"
     exon            4055..4138
                     /gene="NCOR1"
                     /gene_synonym="hN-CoR; N-CoR; N-CoR1; PPP1R109; TRAC1"
                     /inference="alignment:Splign:2.1.0"
     exon            4139..4395
                     /gene="NCOR1"
                     /gene_synonym="hN-CoR; N-CoR; N-CoR1; PPP1R109; TRAC1"
                     /inference="alignment:Splign:2.1.0"
     exon            4396..4756
                     /gene="NCOR1"
                     /gene_synonym="hN-CoR; N-CoR; N-CoR1; PPP1R109; TRAC1"
                     /inference="alignment:Splign:2.1.0"
     exon            4757..4984
                     /gene="NCOR1"
                     /gene_synonym="hN-CoR; N-CoR; N-CoR1; PPP1R109; TRAC1"
                     /inference="alignment:Splign:2.1.0"
     exon            4985..5194
                     /gene="NCOR1"
                     /gene_synonym="hN-CoR; N-CoR; N-CoR1; PPP1R109; TRAC1"
                     /inference="alignment:Splign:2.1.0"
     exon            5195..5344
                     /gene="NCOR1"
                     /gene_synonym="hN-CoR; N-CoR; N-CoR1; PPP1R109; TRAC1"
                     /inference="alignment:Splign:2.1.0"
     exon            5345..5464
                     /gene="NCOR1"
                     /gene_synonym="hN-CoR; N-CoR; N-CoR1; PPP1R109; TRAC1"
                     /inference="alignment:Splign:2.1.0"
     exon            5465..5630
                     /gene="NCOR1"
                     /gene_synonym="hN-CoR; N-CoR; N-CoR1; PPP1R109; TRAC1"
                     /inference="alignment:Splign:2.1.0"
     exon            5631..6124
                     /gene="NCOR1"
                     /gene_synonym="hN-CoR; N-CoR; N-CoR1; PPP1R109; TRAC1"
                     /inference="alignment:Splign:2.1.0"
     exon            6125..6253
                     /gene="NCOR1"
                     /gene_synonym="hN-CoR; N-CoR; N-CoR1; PPP1R109; TRAC1"
                     /inference="alignment:Splign:2.1.0"
     exon            6254..6411
                     /gene="NCOR1"
                     /gene_synonym="hN-CoR; N-CoR; N-CoR1; PPP1R109; TRAC1"
                     /inference="alignment:Splign:2.1.0"
     exon            6412..6635
                     /gene="NCOR1"
                     /gene_synonym="hN-CoR; N-CoR; N-CoR1; PPP1R109; TRAC1"
                     /inference="alignment:Splign:2.1.0"
     exon            6636..6779
                     /gene="NCOR1"
                     /gene_synonym="hN-CoR; N-CoR; N-CoR1; PPP1R109; TRAC1"
                     /inference="alignment:Splign:2.1.0"
     exon            6780..6922
                     /gene="NCOR1"
                     /gene_synonym="hN-CoR; N-CoR; N-CoR1; PPP1R109; TRAC1"
                     /inference="alignment:Splign:2.1.0"
     exon            6923..6976
                     /gene="NCOR1"
                     /gene_synonym="hN-CoR; N-CoR; N-CoR1; PPP1R109; TRAC1"
                     /inference="alignment:Splign:2.1.0"
     exon            6977..7198
                     /gene="NCOR1"
                     /gene_synonym="hN-CoR; N-CoR; N-CoR1; PPP1R109; TRAC1"
                     /inference="alignment:Splign:2.1.0"
     exon            7199..7378
                     /gene="NCOR1"
                     /gene_synonym="hN-CoR; N-CoR; N-CoR1; PPP1R109; TRAC1"
                     /inference="alignment:Splign:2.1.0"
     exon            7379..10705
                     /gene="NCOR1"
                     /gene_synonym="hN-CoR; N-CoR; N-CoR1; PPP1R109; TRAC1"
                     /inference="alignment:Splign:2.1.0"
     regulatory      8434..8439
                     /regulatory_class="polyA_signal_sequence"
                     /gene="NCOR1"
                     /gene_synonym="hN-CoR; N-CoR; N-CoR1; PPP1R109; TRAC1"
                     /note="hexamer: AATAAA"
     polyA_site      8458
                     /gene="NCOR1"
                     /gene_synonym="hN-CoR; N-CoR; N-CoR1; PPP1R109; TRAC1"
                     /note="major polyA site"
     regulatory      9732..9737
                     /regulatory_class="polyA_signal_sequence"
                     /gene="NCOR1"
                     /gene_synonym="hN-CoR; N-CoR; N-CoR1; PPP1R109; TRAC1"
                     /note="hexamer: AATACA"
     regulatory      9744..9749
                     /regulatory_class="polyA_signal_sequence"
                     /gene="NCOR1"
                     /gene_synonym="hN-CoR; N-CoR; N-CoR1; PPP1R109; TRAC1"
                     /note="hexamer: AATACA"
     polyA_site      9758
                     /gene="NCOR1"
                     /gene_synonym="hN-CoR; N-CoR; N-CoR1; PPP1R109; TRAC1"
     polyA_site      9768
                     /gene="NCOR1"
                     /gene_synonym="hN-CoR; N-CoR; N-CoR1; PPP1R109; TRAC1"
     regulatory      10109..10114
                     /regulatory_class="polyA_signal_sequence"
                     /gene="NCOR1"
                     /gene_synonym="hN-CoR; N-CoR; N-CoR1; PPP1R109; TRAC1"
                     /note="hexamer: AATGAA"
     polyA_site      10129
                     /gene="NCOR1"
                     /gene_synonym="hN-CoR; N-CoR; N-CoR1; PPP1R109; TRAC1"
     regulatory      10685..10690
                     /regulatory_class="polyA_signal_sequence"
                     /gene="NCOR1"
                     /gene_synonym="hN-CoR; N-CoR; N-CoR1; PPP1R109; TRAC1"
                     /note="hexamer: AATAAA"
     polyA_site      10705
                     /gene="NCOR1"
                     /gene_synonym="hN-CoR; N-CoR; N-CoR1; PPP1R109; TRAC1"
ORIGIN      
        1 gagtcaagat ggcggccaag gtggcgaagc agcagccgcg gcggcggcgg cggctggagt
       61 gagcgtccga ctcgccgcgc cgaacgaggt cccggtgtag ggccgcgcgc cgtggccgcg
      121 tcccactcct caggccgggg cgcacgtcgg ctcccacgct tagccagctc ccggtggttt
      181 cctagaaaca tgattgttta ttggcattga tctcacagtc tggtgaggac ttctttactg
      241 ataatgtcaa gttcaggtta tcctcccaac caaggagcat tcagcacaga acaaagtcgt
      301 tatcctcctc actctgtcca gtatacattt cccaacaccc gccaccagca ggagttcgca
      361 gtccctgatt atcgttcctc tcatcttgaa gtgagtcagg catcacagct tttgcagcaa
      421 cagcagcagc aacagcttcg aaggcgacct tccttgcttt cagaatttca cccaggttct
      481 gacaggcctc aagaaaggag aactagttat gaaccgtttc atccaggccc atccccagtg
      541 gatcatgatt cactggaatc gaagcgacca cgtctggaac aggtttctga ttctcatttt
      601 cagcgtgtca gtgctgcggt tttgccttta gtgcacccgc tgccagaagg gctgagggct
      661 tctgcagatg ctaagaagga tccagcattc ggaggcaaac atgaagctcc atcctctcca
      721 atttcggggc aaccatgtgg agatgatcaa aatgcttcac cttcaaaact ctcaaaggaa
      781 gagttaatac agagtatgga tcgtgtagat cgagaaattg caaaagtaga acagcagatc
      841 cttaaactga aaaagaaaca acaacagctt gaagaagagg cagctaaacc tcctgagcct
      901 gagaagcccg tgtcccctcc tcctgtggag cagaaacacc gcagtattgt ccaaattatt
      961 tatgatgaga atcggaaaaa agcagaagaa gctcataaaa tttttgaagg tcttggccca
     1021 aaagttgaac tgccactgta taaccagcca tcagatacca aggtgtacca tgagaacatc
     1081 aagacaaacc aggtgatgag gaaaaaactc attttatttt ttaaaagaag aaatcatgca
     1141 agaaaacaaa gggaacaaaa aatctgccag cgttatgatc agctcatgga ggcatgggag
     1201 aaaaaagtgg acagaataga aaataatcct cggaggaaag ctaaagaaag caaaacaagg
     1261 gaatactatg aaaagcagtt tccagaaatt cgaaaacaaa gagaacagca agaaagattt
     1321 cagcgagttg ggcagagggg agctggtctt tcagccacca ttgctaggag tgagcatgag
     1381 atttctgaaa ttattgatgg gctctctgag caggagaata atgagaaaca aatgcggcag
     1441 ctctctgtga ttccacctat gatgtttgat gcagaacaaa gacgagtcaa gttcattaac
     1501 atgaatgggc ttatggagga ccctatgaaa gtgtataaag ataggcagtt tatgaatgtt
     1561 tggactgacc atgaaaagga gatctttaag gacaagttta tccagcatcc aaaaaacttt
     1621 ggactaattg catcatactt ggagaggaag agtgttcctg attgtgtttt gtattactat
     1681 ttaaccaaga aaaatgagaa ttataaagcc ctcgtcagaa ggaattatgg gaaacgcaga
     1741 ggcagaaacc agcaaattgc tcgaccctcg caagaagaaa aagtagaaga aaaagaagag
     1801 gataaagcag aaaaaacaga aaaaaaagaa gaagaaaaga aagatgaaga ggaaaaagat
     1861 gaaaaagaag actccaaaga aaataccaag gaaaaggaca agatagatgg tacagcagaa
     1921 gaaactgagg aaagagagca agccacaccc cgggggcgaa agactgccaa cagtcagggc
     1981 cgccgtaagg gccggatcac caggtccatg acaaacgaag ctgcagctgc cagtgctgca
     2041 gccgcagcgg ctactgaaga gcccccacca cctctgccac cgccaccaga acccatttct
     2101 acagagcctg tggagacctc tcgatggaca gaagaagaaa tggaagttgc taaaaaaggt
     2161 ctagtagaac atggtcgtaa ctgggcagca attgctaaaa tggtgggaac gaaaagtgaa
     2221 gctcaatgta aaaacttcta ttttaactat aaaaggcgac acaatcttga caacctctta
     2281 cagcagcata aacagaaaac ttcacgaaaa cctcgtgaag agcgagatgt gtctcaatgt
     2341 gaaagtgtcg cttccactgt ttctgctcag gaggatgaag atattgaagc ctccaatgaa
     2401 gaagaaaatc cagaagacag cgaagttgaa gctgtcaagc ccagcgagga cagtcctgaa
     2461 aatgctactt ctcgaggaaa cacagaacct gcggttgagc ttgagcccac cacggaaact
     2521 gcacccagta catctccctc cttagcagtt ccaagtacaa aaccagctga agatgaaagt
     2581 gtggagaccc aggtgaatga cagcatcagt gctgagacag cagagcagat ggatgtagat
     2641 cagcaggagc acagtgctga agagggttct gtttgtgatc ccccacccgc taccaaagct
     2701 gactctgtgg acgttgaagt gagggtgcca gaaaaccatg catctaaagt tgaaggtgat
     2761 aataccaaag aaagagactt ggatagagcc agtgagaagg tggaacctag agatgaagat
     2821 ttggtggtag ctcagcaaat aaatgcccaa aggcccgagc cccagtcaga caatgattcc
     2881 agtgccacgt gcagcgctga tgaggatgtg gatggagagc cagagaggca gagaatgttt
     2941 cctatggact caaagccttc actgttaaac cccactggat ctatactcgt ctcatctccg
     3001 ttaaaaccaa atccactgga tctgccacag cttcagcatc gagctgctgt tatcccacca
     3061 atggtatcct gcaccccatg taacatacca attggaaccc cagtgagcgg ctatgctctc
     3121 taccagcgac acattaaagc aatgcatgag tcagcactcc tggaggagca gcggcagaga
     3181 caagaacaga tagatttgga atgtagaagt tctacaagtc catgtggcac atccaagagt
     3241 ccaaacagag agtgggaagt ccttcagcct gctccacatc aagtgataac taatctccct
     3301 gaaggcgttc ggcttccgac aactcgacca accaggccac cgccccctct catcccgtca
     3361 tccaaaacca cagtggcttc agaaaaacca tcttttataa tgggaggctc catctcacag
     3421 ggaacaccag gcacttattt gacttctcat aatcaggctt cctacactca agaaacaccc
     3481 aagccgtcag tgggatctat ctctcttgga ctgccacggc aacaggaatc tgccaaatca
     3541 gctactttgc cctacatcaa gcaggaagaa ttttctcccc gaagccaaaa ctcacaacct
     3601 gagggtctgt tggtcagggc ccaacatgaa ggtgtagtca gaggtaccgc aggagccata
     3661 caagaaggaa gtataactcg gggaactcca accagcaaaa tttcagtgga gagcattcca
     3721 tccctacggg gctctatcac tcagggcacc ccggctctgc cccagactgg cataccaaca
     3781 gaggctttgg tgaaggggtc catttcgaga atgcccattg aagacagcag tcctgagaaa
     3841 ggcagagagg aagctgcatc caaaggccat gttatttatg aaggcaaaag tggacatatc
     3901 ttgtcatatg ataatattaa gaatgcccga gaagggacta ggagtccaag aacagctcat
     3961 gaaatcagtt taaagagaag ctatgaatca gtggaaggaa atataaagca agggatgtca
     4021 atgagggagt ctcctgtatc agcaccgtta gaggggctga tatgccgagc attacccagg
     4081 gggagtcctc attctgacct caaagaaagg actgtattgt ctggctccat aatgcagggg
     4141 acaccaagag caacaactga aagctttgaa gatggcctta aatatcccaa acaaattaaa
     4201 agggaaagtc ctcccatacg agcatttgaa ggtgccatta ccaaaggaaa accatatgat
     4261 ggcatcacca ccatcaaaga aatggggcgt tccattcatg agattccaag gcaagatatt
     4321 ttaactcagg aaagtcggaa aactccagaa gtggtccaga gcacacggcc gataattgag
     4381 ggttccattt cccagggcac accaataaag tttgacaaca actcaggtca atctgccatc
     4441 aaacacaatg tcaaatcctt aatcacgggg cctagcaaac tatcccgtgg aatgcctccg
     4501 ctggaaattg tgccagagaa cataaaagtg gtagaacggg gaaaatatga ggatgtgaaa
     4561 gcaggcgaga ccgtgcgttc ccggcacacg tcagtggtaa gctctggccc ctccgttctt
     4621 aggtccacac tgcatgaagc tcccaaagca caactgagcc ctgggattta tgatgacacc
     4681 agtgcacgga ggacccctgt gagttatcaa aacaccatgt ccagaggctc acccatgatg
     4741 aacagaactt ctgatgttac aatttcttct aacaagtcta ccaatcatga aaggaaatcg
     4801 acactgaccc ctacccagag ggaaagtatc ccagcgaagt ctccagtgcc tggggtggac
     4861 cctgtcgtga gccacagtcc gtttgatccc catcacagag gcagcactgc aggcgaggtt
     4921 tatcggagcc acctgcccac gcacttggat ccagccatgc cttttcacag ggctttggat
     4981 cctgcagcgg ctgcttacct gtttcagaga cagctttcac caactccagg ttacccaagt
     5041 cagtatcagc tttacgcaat ggagaacaca agacagacaa tcttaaatga ttacattacc
     5101 tcacaacaga tgcaagtgaa cttgcgtcca gatgtggcca gaggactctc cccaagagag
     5161 cagccactgg gtctcccata cccagcaacg agaggaatca ttgacctgac caatatgcct
     5221 ccaacaattt tagtgcctca tccaggggga acaagcactc ctcccatgga cagaatcact
     5281 tatattcctg gtacacagat tactttccct cccaggccgt acaactctgc ttccatgtct
     5341 ccaggacacc caacacacct tgcagctgct gcaagtgctg agagggaacg ggaacgggag
     5401 cgggagaagg agcgggagcg ggaacggatt gctgcagctt cctccgacct ctacctgcgg
     5461 ccaggctcag aacagcctgg ccgacctggc agtcatggat atgttcgctc cccttcccct
     5521 tcagtaagaa ctcaggagac catgttgcaa cagagaccca gtgttttcca aggaaccaat
     5581 ggaaccagtg taatcacacc tttggatcca actgctcagc tacgaatcat gccactgcct
     5641 gctgggggcc cttcaataag ccaaggcctg ccagcctccc gttacaacac tgctgcggat
     5701 gccctggctg ctcttgtgga tgctgcagct tctgcacccc agatggatgt gtccaaaaca
     5761 aaagagagta agcatgaagc tgccaggtta gaagaaaatt tgagaagcag gtcagcagca
     5821 gttagtgaac agcagcagct agagcagaaa accctggagg tggagaagag atctgttcag
     5881 tgtttataca cttcttcagc ctttccaagt ggcaagcccc agcctcattc ttcagtagtt
     5941 tattctgagg ctgggaaaga taaagggcct cctccaaaat ccagatatga ggaagagcta
     6001 aggaccagag ggaagactac cattactgca gctaacttca tagacgtgat catcacccgg
     6061 caaattgcct cggacaagga tgcgagggaa cgtggctctc aaagttcaga ctcttctagt
     6121 agcttatctt ctcacaggta tgaaacacct agcgatgcta ttgaggtgat aagtcctgcc
     6181 agctcacctg cgccacccca ggagaaactg cagacctatc agccagaggt tgttaaggca
     6241 aatcaagcgg aaaatgatcc taccagacaa tatgaaggac cattacatca ctatcgacca
     6301 cagcaggaat caccatctcc ccaacaacag ctgccccctt cttcacaggc agagggaatg
     6361 gggcaagtgc ccaggaccca tcggctgatc acacttgctg atcacatctg tcaaattatc
     6421 acacaagatt ttgctagaaa tcaagtttcc tcgcagactc cccagcagcc tcctacttct
     6481 acattccaga actcaccttc tgctttggta tctacacctg tgaggactaa aacatcaaac
     6541 cgttacagcc cagaatccca ggctcagtct gtccatcatc aaagaccagg ttcaagggtc
     6601 tctccagaaa atcttgtgga caaatccagg ggaagtaggc ctggaaaatc cccagagagg
     6661 agtcacgtct cttcggagcc ctacgagccc atctccccac cccaggttcc ggttgtgcat
     6721 gagaaacagg acagcttgct gctcttgtct cagaggggcg cagagcctgc agagcagagg
     6781 aatgatgccc gctcaccagg gagtataagc tacttgcctt cattcttcac caagcttgaa
     6841 aatacatcac ccatggttaa atcaaagaag caggagattt ttcgtaagtt gaactcctct
     6901 ggtggaggtg actctgatat ggcagctgct cagccaggaa ctgagatctt taatctgcca
     6961 gcagttacta cgtcaggctc agttagctct agaggccatt cttttgctga tcctgccagt
     7021 aatcttgggc tggaagacat tatcaggaag gctctcatgg gaagctttga tgacaaagtt
     7081 gaggatcatg gagttgtcat gtcccagcct atgggagtag tgcctggtac tgccaacacc
     7141 tcagttgtga ccagtggtga gacacgaaga gaggaagggg acccatcacc tcattcagga
     7201 ggagtttgca aaccaaagct gatcagcaag tcaaacagca ggaaatctaa gtctcctata
     7261 cctgggcaag gctacttagg aacggaacgg ccctcttcag tctcctctgt acattcagaa
     7321 ggggattacc ataggcagac gccagggtgg gcctgggaag acaggccctc ttcaacaggc
     7381 tcaactcagt ttccttataa ccctctgact atgcggatgc tcagcagtac tccaccaaca
     7441 ccgattgcat gtgctccctc tgcggtgaac caagcagctc ctcaccaaca gaacaggatc
     7501 tgggagcgag agcctgcccc actgctctca gcacagtacg agaccctgtc ggatagtgat
     7561 gactgaactg cacaaagtga ggggaacagg gtgcaggaga gggatctcta gtttttgtgg
     7621 tttaattttt agtagcaggt caaaaacctg ccctcctgtg acttattccc tgagactttt
     7681 caggagagcc agcccacaga tgatgaagaa atgatggaag ttcatttgga gagtcaaatg
     7741 ggaaaaaaac aaacaaaaaa ctgcctttga tacaggcaat tcagtggact ataataatag
     7801 tggagggttg agatgtagag tttttaaaaa gtgaacagtt gctgttctta catctgtaaa
     7861 gaaaaccata atgtctttaa atcactcttc tgtaaataga tgaccttttt gcagtgtata
     7921 tccccttgct gtagtatctg gtgtacttat gttcaaatca gcgcatcaac tttgggggtg
     7981 atttttaaaa atctttttgt ctatctatct ttttaaccct agccttctaa acaacctcat
     8041 acagcccagt tacataatgt tggctgtcac gggcattgta cttttatctg atattgtttc
     8101 ctctaaattc agctttccag tgatgtttaa aatcttgtga aaatgtttag atttttaaca
     8161 cagaccctgt cataaaatct gtacattagg gtcaaaaggt aaaagtaaca aattctgcca
     8221 tattgtaaat ttccagtgca ggctttaatt tttttttttc attagtagca ctgaaaaaat
     8281 attactgcat gggtatgttc tagttcagtt tataaagttt taaaggctta tttgaggcat
     8341 acctcactgt tacgcacact ggtaatttaa ccatgcccct aagtattcct tttctcctgc
     8401 atttgatgca gcccaacaaa gcttttgttt tgaaataaat ttgactaccc tgtccatagc
     8461 tacagtagat tatttgtggt ttaaggctcc tggtgtctca ggttccaaag gaaaagctta
     8521 catatttttc ccttagtttg aatatatgat tggttgggtt aaaagataat gatctgtgta
     8581 gtatttagat aagctttatg ctgcatcctg aaaaactcat ggtgaacaca gtcctttttc
     8641 cccatcacta tggaccagca tttactctca ctttgctccc ttgggacaag agtttactgt
     8701 taaatgtttt catttcacag agtctcaagg tgcaaataat ttaaaagact gaattctaaa
     8761 ctaattatgg tactagaggg ccagttttat ctttcattaa gaattgcttg ctgaatttta
     8821 aagttttttt catacaattt atcatagcat ttaagtatct ttctataaca tagatactaa
     8881 cagttttggg agaatgccac tggtaactgg aaaggggaga aacagatctc tcaggatgat
     8941 aaaaattagc actttacaga ctttcaagta gacctaaact tttaaacaaa agtactcaag
     9001 gcttttaagg aagcagctct gtgattagct actgaccaag accctcctat cactggtgtc
     9061 taatccctat gttacagatg aagacacagg tttagtactt tgcccatata gttaaattag
     9121 tgacagagat aggccataag cccacatttg tcttcagtca aagctttcac tcctgtccct
     9181 gttccactcc tgtatacctg aggtccccaa cataaacttt agatcaggct tagtggtcag
     9241 cattcctagt acttggaaag ttggtatttt ttacaacaga tatatgtaaa catataaaaa
     9301 tttcaaaatg aatgaaaaac agtgactaaa tgttccactt cacagttttc tgctgaattt
     9361 ttttttttca ggtactggta atattttaga gtttgttaat aatttatatt gccaacctac
     9421 cataaaagag attatgatgg tatttttcta tgaccctgag ggtcttaagc tattctgagt
     9481 cagaatacag ttgacccttg aacaacacgg gtttgaactg tgtgggtcca cttatacatg
     9541 gattttcttc cacctctgcc acccaagata gcaagaccaa ccccttctca tcctcagcct
     9601 attcaacatg aagatgacaa ggatgaagac cttcatgatg atccacttcc acttaatgaa
     9661 tagtaaatat attttctctt ccttataatc ttaacaaaca ttttctcttc tctagcttac
     9721 tttattgtaa gaatacagta tataatacat atacaaaata tgtgtcaatc gactatgtta
     9781 tccgtaagac ttctggtcag cagtaggcca tgagtagtta agttttggag gagtcaaagt
     9841 tagatgtgga tttttgacta cttagggggt ctatgcccct aactcctgca ttatttgaag
     9901 gtcaaccgta tagtttctga gaacatgtca gatcagagcc taacttctta ctcttgcagt
     9961 tctacctgag gacccgaagg tgaggtgctg tgaaccactc cctccatcct catcataatg
    10021 catgtgcgta ttactttatt taccatcacc tggagaagaa atctcagaat gagagttaaa
    10081 atccaataat agttcttggt tcaaaataaa tgaaaggaca gaattctcac atggtttacc
    10141 tatggaggtt caccttatca tgatttaagt ggtaagcaca gagcagcact gacaacttac
    10201 tgtggttcac tgcaaaccaa aacatgatat tctttgtaga cttagatttc agtgttctga
    10261 cactatatcc ttacacgtga tttttttagc acccagaact aaattaaggt cttcctaata
    10321 ctcttcataa aagtattctg acagccagtt ttccactgca tgtttatgac tgcaaatttc
    10381 ataatgcttt taattttggt acactgagtg attctatttt aaaaatattt atgcccagaa
    10441 aactccagtg accattggac agttaaaaaa ttttaatgac acgattttaa ccaattcact
    10501 tttgaattta gaccaatcag taaaggagat cagtcctcct tttgcttcag taccttattt
    10561 tacaacagtg taaatgaact gtaatgaaaa cacccacatg aagagactgt cctgaaaact
    10621 cctagtgttt ccaacaacga gaccatgagc tgagtcactg tggatgattt aaaattaata
    10681 aataaataaa acttggaatg aaaaa
//
