LOCUS       NM_001010980            3980 bp    mRNA    linear   PRI 04-APR-2024
DEFINITION  Homo sapiens non-compact myelin associated protein (NCMAP), mRNA.
ACCESSION   NM_001010980 XM_375700
VERSION     NM_001010980.5
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 3980)
  AUTHORS   Ryu,E.J., Yang,M., Gustin,J.A., Chang,L.W., Freimuth,R.R.,
            Nagarajan,R. and Milbrandt,J.
  TITLE     Analysis of peripheral nerve expression profiles identifies a novel
            myelin glycoprotein, MP11
  JOURNAL   J Neurosci 28 (30), 7563-7573 (2008)
   PUBMED   18650334
  REMARK    GeneRIF: This study identified an evolutionarily conserved novel
            component of myelin called Mp11. The Mp11 genomic locus contains
            multiple conserved Egr binding sites, and Mp11 induction is
            regulated by the expression of Egr2 and expression in peripheral
            nerve.
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CB961010.1, BC147014.1 and AL445686.14.
            
            On Nov 23, 2018 this sequence version replaced NM_001010980.4.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK124519.1, DA093459.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1968832, SAMEA1970526
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000374392.3/ ENSP00000363513.2
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-85                CB961010.1         40-124
            86-1039             BC147014.1         18-971
            1040-3980           AL445686.14        59824-62764
FEATURES             Location/Qualifiers
     source          1..3980
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="1"
                     /map="1p36.11"
     gene            1..3980
                     /gene="NCMAP"
                     /gene_synonym="C1orf130; MP11"
                     /note="non-compact myelin associated protein"
                     /db_xref="GeneID:400746"
                     /db_xref="HGNC:HGNC:29332"
     exon            1..83
                     /gene="NCMAP"
                     /gene_synonym="C1orf130; MP11"
                     /inference="alignment:Splign:2.1.0"
     exon            84..172
                     /gene="NCMAP"
                     /gene_synonym="C1orf130; MP11"
                     /inference="alignment:Splign:2.1.0"
     CDS             91..399
                     /gene="NCMAP"
                     /gene_synonym="C1orf130; MP11"
                     /note="myelin protein of 11 kDa"
                     /codon_start=1
                     /product="noncompact myelin-associated protein"
                     /protein_id="NP_001010980.1"
                     /db_xref="CCDS:CCDS30632.1"
                     /db_xref="GeneID:400746"
                     /db_xref="HGNC:HGNC:29332"
                     /translation="MTTATPLGDTTFFSLNMTTRGEDFLYKSSGAIVAAVVVVVIIIF
                     TVVLILLKMYNRKMRTRRELEPKGPKPTAPSAVGPNSNGSQHPATVTFSPVDVQVETR
                     "
     exon            173..257
                     /gene="NCMAP"
                     /gene_synonym="C1orf130; MP11"
                     /inference="alignment:Splign:2.1.0"
     exon            258..3980
                     /gene="NCMAP"
                     /gene_synonym="C1orf130; MP11"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3960..3965
                     /regulatory_class="polyA_signal_sequence"
                     /gene="NCMAP"
                     /gene_synonym="C1orf130; MP11"
                     /note="hexamer: AATAAA"
     polyA_site      3980
                     /gene="NCMAP"
                     /gene_synonym="C1orf130; MP11"
                     /note="major polyA site"
ORIGIN      
        1 gtggcagcgc cgggcggcgg cggggaccct ggctgggagc gcggcggtgc cggcgggagg
       61 ccgagcgggg ctcgacagag caggatcgag atgaccacag ccacccctct gggggatacc
      121 accttcttct cactgaacat gaccaccagg ggagaagact tcctgtataa gagttctgga
      181 gccattgttg ctgccgttgt ggtggttgtc atcatcatct tcaccgtggt tctgatcctg
      241 ctgaagatgt acaacaggaa aatgaggacg aggcgggaac tagagcccaa gggccccaag
      301 ccaaccgccc cttctgccgt gggcccaaac agcaacggca gccaacaccc agcaactgtg
      361 accttcagtc ctgttgacgt ccaggtggag acgcgatgac ctctaccctg gcgctatctc
      421 caccactgtc caaagagcct ctccagagtc aagacccaga ggcacactct ctggcagctt
      481 cacaatgagc ttcttctggt caggtcgaca gagacatctt tgacgcaatc tctgatgctt
      541 ccagcaatcc tcaaccttgt ctgccctgcc ctaccccaac tgtgtccaca tccctgccgc
      601 caccccacca aaaagctgca gaacattctt ttgtcatctg atgaggtaga gctatgttgg
      661 gaatccacca atgtgggctt ggctttcccc cacactgtag ttagacagat agacagatag
      721 cccaggagcc aggtgtcagg gagcactgct gagagtatca caataggatc tgtcacgggg
      781 ttcatatcag atgaagcgcc gtatccactg cttcacagag caaaacattc aatcccataa
      841 ccaggcacag gggaactaac ttggactaac taaccagaaa accttgttaa cgtataactt
      901 gttccagtac tacatctctg cctgctggct catgacaatt gctcagcaca ttttcccctc
      961 ttgaagaaag gttgcaagaa gaactaaatt atcctcaaaa gatttctgct tcattagtaa
     1021 agagtcagtg atggaatagg gtgactctgc agaatagtgg cctctagggt aggagcttgt
     1081 tgtgttgtcc gtgggcctgg aatgatcctg gtggctgatc agggtccttc tcccactctg
     1141 ggctgtatca accctgacgg tcttggtctt tggctcccct ttatctggat tctgagcacg
     1201 ctgactgtcc tgttaatgcc ttccctccaa ggaccagtat ttggagatta attagattac
     1261 aactctatct atgttacctt tgtccttcct ggtcaccttg cagattcaag acatgttcaa
     1321 agcaacacat tcacaaccca tttctattct atagcaacct cgtctgtgac tccttagcct
     1381 ggagaacaat ctaccaagaa gagaaagtat ctggaattaa gaagtcctac catccaagcc
     1441 ctacttcctg gttgtgtggc cttggaaaag tgactcaacc tctttatatt cagtttccta
     1501 accatgaagt ggaaatgata acacctgcct cattggggca ctataacaag tgaaggactt
     1561 aggaaaacat ctggagtata gcgcctggca cccaggagat gcttaataaa tgggaaccag
     1621 gattcttttt cttttctttt ttcttttctt tttttttttt ttttgagaca gagcctcaat
     1681 ctgtcacctg ggctggagtg cagtggcacg ctcacagctc gctgcagcct tgaactcctg
     1741 ggctcaaggg atgctccctc ctcagcctcc agagtagctg ggactacagg tatgtgtcac
     1801 ctcaccaggc taattttttt attttttatt tttgtagaga tggggtctcg ctgtgttgcc
     1861 caggctggtc ttgaacccct ggcctcaagt gatccttctg ctttggcctc ccaaagtgct
     1921 gggattacag gcatggacta tggtgcccag cctaggagcc aacattatta ttattatagg
     1981 cttttttttc aattgcaaga tagacatttc ttcacatttt aatgattctg aaatcagaac
     2041 atatcttgca attgatgggt tcattaatat aattgtagtt ctttacttcc tctcaaaaac
     2101 ttgtgatctt ataattgatg gcatcttgga aacaaggtaa taaatctcta ttctgttaaa
     2161 gaaagtgaca cactttgaca tttaacctca aattttagga gtctctccct cttggggtca
     2221 gaaatccctt ctgaggccag gtgtcgtggc tcatgcctgt aatcccagca ctttgggagg
     2281 ctgaggcagg cgggtcactt gaggtcagga gtttgagacc agcctggcca acatggcaaa
     2341 accctgtctc tactaataat acaaaattta gctgggcatg gtggcatgca cctgtaatcc
     2401 cactactagg gaggctgtgg catgagaatc acttgaacct ggaaggcaga ggttgcagtg
     2461 agccaagatc gtgccactgc actccagcct gggcaacaga gtgaaactgc atctcaaaaa
     2521 aagaaaaatc cattatgagg ggaaatcaag agtcagggag gtaagaggtc ttacccaggg
     2581 tcacacagct catgatatcc cactgtaaaa atactctgtg gaatagctct ggagaaatac
     2641 tggcacattc ttcctctctg gtcattattt cttcctactg tgtttaaata tccaccaagt
     2701 gtcaaggact ttgtaagatg ctttcacata aattatctca taggattaaa ttttcccaaa
     2761 aacctgggga ggaattattt tttccaaaac agatgataat ttctgattca aagagaaaga
     2821 aaacaaagta cttttccaaa gtcacacagc tagtaagtca caaagacaag actcaaaacc
     2881 aggtctcttg actccaaagt ctgtcttttt tgtgaagtca cactcctctg ctggcccagc
     2941 tcaaagcagc acagattctt tatgggctga acaaggggag tacgggtttg tccatgtgtt
     3001 tgagtagaga tcagggttct ggcttccagg ctgaaggtga gggaaaagcc acttctaact
     3061 cctttgggca tccatgctca cggccaaaag agccccttct caacacatcc aagtgctaag
     3121 gattcctgct tcattcaagc tactacttag gcccaaggag caaggggtag aatggcatct
     3181 aaccagagca aagccatttc tttgagggct caagccataa acaaatatgc tcccctaaac
     3241 atattcggct tgaaaaagtt gttttggggc agctgtggtg gtgcacccct gtaatcccag
     3301 ccctttggga gtcagaggca gtcagtcact tgagcccagg agttcaagac tagcctgggc
     3361 aacacggcga aacctcgtct ctacaaaaaa tacaaaaatt aaccaagcgt ggtagtgcac
     3421 gcctgtattc ccagctactt gggaggctga ggtaggagga tggcttgagc ctgggaggca
     3481 gaggttgcag tgagctgaga tcgcgccact gcactccagc cggggtgaca gagccagacc
     3541 ctgtctcaaa gcatatttca accctaaaac tagactcttc tgcccacagt gcagtcttct
     3601 aagggttacc ctctggtata tgttcttttg ctaaatgaag gcttggagtt ggagggaaga
     3661 aggggagatg gagtggtgag ggcgagtcaa ataaaaggat ttgagtgtct cgtttttgac
     3721 taatgaagat gattcaataa acatcctgta agaagggttc ctatgtgcaa gttgaggtgc
     3781 tactaagtac attaagacac aattgctgct ctcaaggagt tagcagctgg tctcatgcag
     3841 ggatctcacc acgtggttat gtattttgtt tctgatgagg tgcctttctt agcagatgct
     3901 gccttatttg gccactgaaa caatcaaagc taataaatgc ttaaagaaaa atatctgaca
     3961 ataaaaaggt ttaaatcaaa
//
