LOCUS       NM_015341               6030 bp    mRNA    linear   PRI 19-AUG-2024
DEFINITION  Homo sapiens non-SMC condensin I complex subunit H (NCAPH),
            transcript variant 1, mRNA.
ACCESSION   NM_015341
VERSION     NM_015341.5
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 6030)
  AUTHORS   Huang,P., Zhao,H., Sun,R., Liu,C., Wu,L., Wang,Y., Gan,Z., Yang,X.
            and Du,J.
  TITLE     MiR-1976/NCAPH/P65 axis inhibits the malignant phenotypes of lung
            adenocarcinoma
  JOURNAL   Sci Rep 14 (1), 11211 (2024)
   PUBMED   38755247
  REMARK    GeneRIF: MiR-1976/NCAPH/P65 axis inhibits the malignant phenotypes
            of lung adenocarcinoma.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6030)
  AUTHORS   Chen,Z., Ruan,W., Guo,C., Chen,K., Li,L., Tian,J., Hu,Z., Peng,D.
            and Zeng,X.
  TITLE     Non-SMC condensin I complex subunit H participates in
            anti-programmed cell death-1 resistance of clear cell renal cell
            carcinomas
  JOURNAL   Cell Prolif 56 (7), e13400 (2023)
   PUBMED   36642844
  REMARK    GeneRIF: Non-SMC condensin I complex subunit H participates in
            anti-programmed cell death-1 resistance of clear cell renal cell
            carcinomas.
REFERENCE   3  (bases 1 to 6030)
  AUTHORS   Liu,Y., Ma,X., Feng,L., Lin,Z. and Zhou,X.
  TITLE     An integrative pan-cancer analysis reveals the carcinogenic effects
            of NCAPH in human cancer
  JOURNAL   Math Biosci Eng 20 (1), 76-92 (2023)
   PUBMED   36650758
  REMARK    GeneRIF: An integrative pan-cancer analysis reveals the
            carcinogenic effects of NCAPH in human cancer.
REFERENCE   4  (bases 1 to 6030)
  AUTHORS   Kim,J.H., Youn,Y. and Hwang,J.H.
  TITLE     NCAPH Stabilizes GEN1 in Chromatin to Resolve Ultra-Fine DNA
            Bridges and Maintain Chromosome Stability
  JOURNAL   Mol Cells 45 (11), 792-805 (2022)
   PUBMED   36380731
  REMARK    GeneRIF: NCAPH Stabilizes GEN1 in Chromatin to Resolve Ultra-Fine
            DNA Bridges and Maintain Chromosome Stability.
REFERENCE   5  (bases 1 to 6030)
  AUTHORS   Li,C., Meng,J. and Zhang,T.
  TITLE     NCAPH is a prognostic biomarker and associated with immune
            infiltrates in lung adenocarcinoma
  JOURNAL   Sci Rep 12 (1), 9578 (2022)
   PUBMED   35688915
  REMARK    GeneRIF: NCAPH is a prognostic biomarker and associated with immune
            infiltrates in lung adenocarcinoma.
            Publication Status: Online-Only
REFERENCE   6  (bases 1 to 6030)
  AUTHORS   Nousiainen,M., Sillje,H.H., Sauer,G., Nigg,E.A. and Korner,R.
  TITLE     Phosphoproteome analysis of the human mitotic spindle
  JOURNAL   Proc Natl Acad Sci U S A 103 (14), 5391-5396 (2006)
   PUBMED   16565220
REFERENCE   7  (bases 1 to 6030)
  AUTHORS   Heale,J.T., Ball,A.R. Jr., Schmiesing,J.A., Kim,J.S., Kong,X.,
            Zhou,S., Hudson,D.F., Earnshaw,W.C. and Yokomori,K.
  TITLE     Condensin I interacts with the PARP-1-XRCC1 complex and functions
            in DNA single-strand break repair
  JOURNAL   Mol Cell 21 (6), 837-848 (2006)
   PUBMED   16543152
  REMARK    GeneRIF: Our results identify a SSB-specific response of condensin
            I through PARP-1 and demonstrate a role for condensin in SSB.
            repair.
REFERENCE   8  (bases 1 to 6030)
  AUTHORS   Cabello,O.A., Eliseeva,E., He,W.G., Youssoufian,H., Plon,S.E.,
            Brinkley,B.R. and Belmont,J.W.
  TITLE     Cell cycle-dependent expression and nucleolar localization of
            hCAP-H
  JOURNAL   Mol Biol Cell 12 (11), 3527-3537 (2001)
   PUBMED   11694586
REFERENCE   9  (bases 1 to 6030)
  AUTHORS   Kimura,K., Cuvier,O. and Hirano,T.
  TITLE     Chromosome condensation by a human condensin complex in Xenopus egg
            extracts
  JOURNAL   J Biol Chem 276 (8), 5417-5420 (2001)
   PUBMED   11136719
REFERENCE   10 (bases 1 to 6030)
  AUTHORS   Cabello,O.A., Baldini,A., Bhat,M., Bellen,H. and Belmont,J.W.
  TITLE     Localization of BRRN1, the human homologue of Drosophila barr, to
            2q11.2
  JOURNAL   Genomics 46 (2), 311-313 (1997)
   PUBMED   9417923
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from AC021188.6 and D38553.1.
            
            On Nov 23, 2018 this sequence version replaced NM_015341.4.
            
            Summary: This gene encodes a member of the barr gene family and a
            regulatory subunit of the condensin complex. This complex is
            required for the conversion of interphase chromatin into condensed
            chromosomes. The protein encoded by this gene is associated with
            mitotic chromosomes, except during the early phase of chromosome
            condensation. During interphase, the protein has a distinct
            punctate nucleolar localization. Alternatively spliced transcript
            variants encoding different proteins have been described. [provided
            by RefSeq, Jul 2013].
            
            Transcript Variant: This variant (1) represents the longest
            transcript and encodes the longest protein (isoform 1).
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR3476690.64332.1, BC024211.2
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1965299, SAMEA1966682
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000240423.9/ ENSP00000240423.4
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-45                AC021188.6         70186-70230
            46-2771             D38553.1           1-2726
            2772-6030           AC021188.6         108253-111511
FEATURES             Location/Qualifiers
     source          1..6030
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="2"
                     /map="2q11.2"
     gene            1..6030
                     /gene="NCAPH"
                     /gene_synonym="BRRN1; CAP-H; CAPH; MCPH23; NCAPH1"
                     /note="non-SMC condensin I complex subunit H"
                     /db_xref="GeneID:23397"
                     /db_xref="HGNC:HGNC:1112"
                     /db_xref="MIM:602332"
     exon            1..83
                     /gene="NCAPH"
                     /gene_synonym="BRRN1; CAP-H; CAPH; MCPH23; NCAPH1"
                     /inference="alignment:Splign:2.1.0"
     CDS             65..2290
                     /gene="NCAPH"
                     /gene_synonym="BRRN1; CAP-H; CAPH; MCPH23; NCAPH1"
                     /note="isoform 1 is encoded by transcript variant 1;
                     condensin complex subunit 2; chromosome-associated protein
                     H; barren homolog 1"
                     /codon_start=1
                     /product="condensin complex subunit 2 isoform 1"
                     /protein_id="NP_056156.2"
                     /db_xref="CCDS:CCDS2021.1"
                     /db_xref="GeneID:23397"
                     /db_xref="HGNC:HGNC:1112"
                     /db_xref="MIM:602332"
                     /translation="MGPPGPALPATMNNSSSETRGHPHSASSPSERVFPMPLPRKAPL
                     NIPGTPVLEDFPQNDDEKERLQRRRSRVFDLQFSTDSPRLLASPSSRSIDISATIPKF
                     TNTQITEHYSTCIKLSTENKITTKNAFGLHLIDFMSEILKQKDTEPTNFKVAAGTLDA
                     STKIYAVRVDAVHADVYRVLGGLGKDAPSLEEVEGHVADGSATEMGTTKKAVKPKKKH
                     LHRTIEQNINNLNVSEADRKCEIDPMFQKTAASFDECSTAGVFLSTLHCQDYRSELLF
                     PSDVQTLSTGEPLELPELGCVEMTDLKAPLQQCAEDRQICPSLAGFQFTQWDSETHNE
                     SVSALVDKFKKNDQVFDINAEVDESDCGDFPDGSLGDDFDANDEPDHTAVGDHEEFRS
                     WKEPCQVQSCQEEMISLGDGDIRTMCPLLSMKPGEYSYFSPRTMSMWAGPDHWRFRPR
                     RKQDAPSQSENKKKSTKKDFEIDFEDDIDFDVYFRKTKAATILTKSTLENQNWRATTL
                     PTDFNYNVDTLVQLHLKPGTRLLKMAQGHRVETEHYEEIEDYDYNNPNDTSNFCPGLQ
                     AADSDDEDLDDLFVGPVGNSDLSPYPCHPPKTAQQNGDTPEAQGLDITTYGESNLVAE
                     PQKVNKIEIHYAKTAKKMDMKKLKQSMWSLLTALSGKEADAEANHREAGKEAALAEVA
                     DEKMLSGLTKDLQRSLPPVMAQNLSIPLAFACLLHLANEKNLKLEGTEDLSDVLVRQG
                     D"
     exon            84..336
                     /gene="NCAPH"
                     /gene_synonym="BRRN1; CAP-H; CAPH; MCPH23; NCAPH1"
                     /inference="alignment:Splign:2.1.0"
     exon            337..427
                     /gene="NCAPH"
                     /gene_synonym="BRRN1; CAP-H; CAPH; MCPH23; NCAPH1"
                     /inference="alignment:Splign:2.1.0"
     exon            428..520
                     /gene="NCAPH"
                     /gene_synonym="BRRN1; CAP-H; CAPH; MCPH23; NCAPH1"
                     /inference="alignment:Splign:2.1.0"
     exon            521..659
                     /gene="NCAPH"
                     /gene_synonym="BRRN1; CAP-H; CAPH; MCPH23; NCAPH1"
                     /inference="alignment:Splign:2.1.0"
     exon            660..784
                     /gene="NCAPH"
                     /gene_synonym="BRRN1; CAP-H; CAPH; MCPH23; NCAPH1"
                     /inference="alignment:Splign:2.1.0"
     exon            785..974
                     /gene="NCAPH"
                     /gene_synonym="BRRN1; CAP-H; CAPH; MCPH23; NCAPH1"
                     /inference="alignment:Splign:2.1.0"
     exon            975..1066
                     /gene="NCAPH"
                     /gene_synonym="BRRN1; CAP-H; CAPH; MCPH23; NCAPH1"
                     /inference="alignment:Splign:2.1.0"
     exon            1067..1272
                     /gene="NCAPH"
                     /gene_synonym="BRRN1; CAP-H; CAPH; MCPH23; NCAPH1"
                     /inference="alignment:Splign:2.1.0"
     exon            1273..1421
                     /gene="NCAPH"
                     /gene_synonym="BRRN1; CAP-H; CAPH; MCPH23; NCAPH1"
                     /inference="alignment:Splign:2.1.0"
     exon            1422..1528
                     /gene="NCAPH"
                     /gene_synonym="BRRN1; CAP-H; CAPH; MCPH23; NCAPH1"
                     /inference="alignment:Splign:2.1.0"
     exon            1529..1651
                     /gene="NCAPH"
                     /gene_synonym="BRRN1; CAP-H; CAPH; MCPH23; NCAPH1"
                     /inference="alignment:Splign:2.1.0"
     exon            1652..1762
                     /gene="NCAPH"
                     /gene_synonym="BRRN1; CAP-H; CAPH; MCPH23; NCAPH1"
                     /inference="alignment:Splign:2.1.0"
     exon            1763..1945
                     /gene="NCAPH"
                     /gene_synonym="BRRN1; CAP-H; CAPH; MCPH23; NCAPH1"
                     /inference="alignment:Splign:2.1.0"
     exon            1946..2062
                     /gene="NCAPH"
                     /gene_synonym="BRRN1; CAP-H; CAPH; MCPH23; NCAPH1"
                     /inference="alignment:Splign:2.1.0"
     exon            2063..2154
                     /gene="NCAPH"
                     /gene_synonym="BRRN1; CAP-H; CAPH; MCPH23; NCAPH1"
                     /inference="alignment:Splign:2.1.0"
     exon            2155..2230
                     /gene="NCAPH"
                     /gene_synonym="BRRN1; CAP-H; CAPH; MCPH23; NCAPH1"
                     /inference="alignment:Splign:2.1.0"
     exon            2231..6030
                     /gene="NCAPH"
                     /gene_synonym="BRRN1; CAP-H; CAPH; MCPH23; NCAPH1"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2752..2757
                     /regulatory_class="polyA_signal_sequence"
                     /gene="NCAPH"
                     /gene_synonym="BRRN1; CAP-H; CAPH; MCPH23; NCAPH1"
                     /note="hexamer: AATAAA"
     regulatory      2764..2769
                     /regulatory_class="polyA_signal_sequence"
                     /gene="NCAPH"
                     /gene_synonym="BRRN1; CAP-H; CAPH; MCPH23; NCAPH1"
                     /note="hexamer: AATAAT"
     polyA_site      2770
                     /gene="NCAPH"
                     /gene_synonym="BRRN1; CAP-H; CAPH; MCPH23; NCAPH1"
     polyA_site      2782
                     /gene="NCAPH"
                     /gene_synonym="BRRN1; CAP-H; CAPH; MCPH23; NCAPH1"
                     /note="major polyA site"
     regulatory      4535..4540
                     /regulatory_class="polyA_signal_sequence"
                     /gene="NCAPH"
                     /gene_synonym="BRRN1; CAP-H; CAPH; MCPH23; NCAPH1"
                     /note="hexamer: AATAAA"
     polyA_site      4559
                     /gene="NCAPH"
                     /gene_synonym="BRRN1; CAP-H; CAPH; MCPH23; NCAPH1"
     regulatory      6009..6014
                     /regulatory_class="polyA_signal_sequence"
                     /gene="NCAPH"
                     /gene_synonym="BRRN1; CAP-H; CAPH; MCPH23; NCAPH1"
                     /note="hexamer: AATAAA"
     polyA_site      6030
                     /gene="NCAPH"
                     /gene_synonym="BRRN1; CAP-H; CAPH; MCPH23; NCAPH1"
ORIGIN      
        1 gttacggcgc tcaggcgtct cgacgcgcgc gatttaaaac cagctcagga gacgccaagg
       61 aaagatggga cctcccggcc cagcactgcc agccacaatg aataactctt cttcagagac
      121 gcgaggacac ccccacagtg cctcctctcc ttcagagcgt gtgttcccga tgcccctgcc
      181 caggaaggcg cctctcaata ttcctggcac cccagtcctc gaagactttc ctcagaatga
      241 cgatgagaag gagcggctgc agcggaggcg ctcgagggtc tttgatctgc agttcagcac
      301 tgactcacct cgcttattgg cctccccctc cagcaggagt attgacattt cagctactat
      361 ccccaagttt acaaacacgc agattacgga acattactcc acctgtatca aactgtccac
      421 tgaaaataaa atcactacca agaatgcttt tggtttgcac ttgattgatt ttatgtcaga
      481 gattcttaaa cagaaagaca ccgaaccaac caactttaaa gtggctgcgg gtactctgga
      541 tgccagcacc aagatctatg ctgtgcgcgt ggatgccgtc catgccgatg tatacagagt
      601 ccttgggggg ctgggcaaag atgcaccgtc tttggaagaa gtagaaggcc atgttgctga
      661 tggaagtgct actgaaatgg gaacaaccaa aaaggctgta aagccaaaga agaagcactt
      721 acacagaact attgagcaga acataaacaa cctcaatgtc tccgaagcag atcggaagtg
      781 tgagattgat cccatgtttc agaagacagc agcctcattt gatgagtgca gcacagcagg
      841 ggtgtttctg tccactctcc actgccagga ctacagaagt gaactgctgt ttccctctga
      901 tgtccagact ctctccacgg gagaacctct cgagttgcca gagttaggtt gtgtagaaat
      961 gacagattta aaagcgccct tgcagcagtg tgcagaagat cgccagatct gcccttccct
     1021 ggccgggttc cagtttacac agtgggacag tgaaacacat aatgagtctg tgtcggccct
     1081 ggtagacaag tttaagaaga atgaccaggt atttgacatc aatgctgaag ttgacgagag
     1141 tgactgtgga gacttccccg atgggtccct gggggatgac tttgatgcca acgatgaacc
     1201 tgaccacacc gcagttgggg atcatgaaga gttcaggagc tggaaggagc cctgccaggt
     1261 tcagagctgc caggaagaaa tgatttccct tggggatgga gacatcagga ccatgtgccc
     1321 ccttctgtct atgaaacctg gagaatattc ttatttcagt cctcggacca tgtcgatgtg
     1381 ggctggcccg gatcactggc gctttaggcc tcgacgcaaa caagatgctc cttcccaatc
     1441 agaaaacaaa aagaagagta caaaaaaaga ttttgaaatt gactttgaag atgatattga
     1501 ctttgatgta tattttagaa aaacaaaggc tgctactatt ctgaccaagt ccactttgga
     1561 gaaccagaat tggagagcta ccacccttcc tacagatttc aactacaatg ttgacactct
     1621 ggtccagctt cacctcaaac caggcaccag gttacttaag atggcccagg gccatagggt
     1681 agagactgag cattatgaag aaattgaaga ctatgattac aacaacccta acgacacctc
     1741 caacttttgc cctggattac aggctgctga cagtgatgat gaagatttgg atgacttatt
     1801 tgtgggacct gttgggaact ctgacctctc accttatcct tgccatccac ctaagacagc
     1861 acaacagaat ggtgacactc cagaagccca aggattagac atcacaacat atggggagtc
     1921 aaacttggta gctgagcctc agaaggtaaa taaaattgaa attcactatg ccaagactgc
     1981 caaaaagatg gacatgaaga aactgaagca gagcatgtgg agtctgctga cagcgctctc
     2041 cggaaaggag gcagatgcag aggcaaacca cagggaagct ggaaaagaag cggccctggc
     2101 agaagtggct gacgagaaga tgcttagcgg gctcacgaag gacctgcaga ggagcctgcc
     2161 ccctgtcatg gctcagaacc tctccatacc tctggctttt gcctgtctcc tacatttagc
     2221 caatgaaaag aatctaaaac tggaaggaac agaggacctc tctgatgttc ttgtgaggca
     2281 aggagattga gttcactatg gagaagtcag cagcaggagg cccatccctt actcagttgc
     2341 cgggacatcc ccagtctcgg gggaagaaga tgccatgggc ttatacccag gctgtagcca
     2401 actaccaacg tgcctgtttg tttgttgctc tttccttctc tccatcatag tctgggtgcc
     2461 agcgccctga agctccgtgc tcaactgatt aaactttact gccctatggt gaccatctag
     2521 gagaggggag ggcagagggg gtgagggtac tattctggat tgagaaaacc tatatccatt
     2581 ctttatatca atgtatagtt ttagtctcct aaattgatct gttattttcc aaactattct
     2641 cttgtagaaa attttccagt gggcacttaa tggtgccctt gaagaacttc ctaatccatg
     2701 tacataaaat acatcatatg tacacttata aatgtatata gaatgctcaa aaataaaatt
     2761 cttaataata gaactggcaa aatatttgag tgtccactag atgagtatca gacctagtcc
     2821 ttacccttag ggggatgcag tcctggttgt tatccaggat acacacctgt cagtataagg
     2881 cagaagatgc ctaagggcca agatggtttg cctcggagga gaatggaaga gagagattgc
     2941 tgactggaca ttcagatgca agactgggtc ctgcttaaat cccaggattc tgctggaggg
     3001 agctgatagt gatacttgtc ccttctgtac attgcttcat gtagccttct cagcatccct
     3061 aggagaaact tactattgtg actctcatgt tggaggagga aacggacacc caaggtagag
     3121 gaacttgcaa aagggcagcc ggcaaactgt caggggtggc ctgagcctgg caatctgcct
     3181 ccagagtctg ctctcggcca ttgtgctatg tgctacctgg ataggtcata caggctcagc
     3241 agtgggtgga gagcagtgct cagatttgtc catctccaca gaatgcagca cacacacaaa
     3301 tgtacaagtt cttcccctaa cctcagagga ataggggaat taactttgct tgcaatttgg
     3361 aacaatatta tagatgttga tccaagtagt tctgttactg gctggtcctg gatctctgcc
     3421 agaacacccg tcatcattga ctggctaaat agagatcttg gatataggcc agaagcagtg
     3481 aagtatataa ttggaaattg ctcctgataa taacttcctt cttagccaaa aaccacacaa
     3541 aacaaaaata atcccctccc cacaggaata tgctttccaa attgtgtcca aaacattacc
     3601 tgctctgtta tattgagaag gttagagact tcagagcatg cttagaaaaa gcagtggtgc
     3661 cacaggtgag actccacact ctgtcttgct ggggctgaag cctccatcac tttcccaggc
     3721 caggttagtg ctgggcttct tgctttcctt ctattcctga gagtagaact ggctaagccc
     3781 attccttccc tcagtcagcc ccacttctct atagtgggtt ctgggggtgg ggggctgaat
     3841 taccagtaaa actagaaaga ttgggaccaa gtgcagtggc ccacacctgt aaatcctagc
     3901 gctttgaaag gaagaggcag gaggattgct tgaagtcagg agttcaagac cagcctgggc
     3961 aaaatagaac cccatcttta aaaaaaaagt ttaaaaatta gccaggtacg gaggtgtgtg
     4021 cctgtaatcc cagctactca gaaggctgag gtgggataat cacttgagcc caggagtttg
     4081 aggctgcagt gagctgtgat cacactactg cattccagcc aggacaacag agtgagatcc
     4141 tatctcttaa acaaaaaaaa aaactggcga gttcaatacc aacttctaca atgaaatccc
     4201 cttcccccca caaccctgct tctcctaagt ttccctcatt acatggttgc tgtgggctat
     4261 gtgtgctgtg gtctgaatgt ttgtgtctaa aattcacatg ttggtattaa gagatagggc
     4321 ctttgggagg tgattaggtt atgagggcag atccctcgtg aatgggatta gtgctcttat
     4381 aaaagaggcc tgaggaagct tgttcgttcc tcttgccctt ctgccatgta aggatgcaat
     4441 gagaaggcac catctgtgag caaggagccc ctcaccagac agcaaatctg ccggcgtctt
     4501 gatcttggac ttctcagcct ctagaactgt gaacaataaa tctattgttt ataaattaag
     4561 cagtctaagt cattttgtta tagcagacaa attgactaag acagtgggta tgcaagataa
     4621 gtttatttta tataaaatac tttgggaagt aggtgttcta ggactggtgt gacagttcca
     4681 tgaaattatg agagaccggg gatccttcca gctcatcctt ctgtttcagt gtggctgctg
     4741 gaatccagcc atcacatcca tagtctaagc agcaggacga aggactgggg gaaaagagaa
     4801 ctgctgctcc ctgttaaatc agtttcctgg gggtcgatat gaatatttgc cacctcaggg
     4861 tgccacaaag gtccccacca gcaagaaggc tcccaccaga tatggactca acctgggact
     4921 tttcagcctc cataactgta ataaattcct ttgtcagtta cccagtttca ggtattctgt
     4981 tataggtaac agaaaacaaa ctaatacaag tggtaatgtg tccagctaaa aatttgggtt
     5041 ctgttaaggt taaaagaaaa tttgaggtag ccagcagtat ctgcctcaga tgctgagaag
     5101 cctcctgaga taagagcgta taccatgtcc ataactgaag ttttaacatt ctctgccaaa
     5161 cagaaccaga atttaagggc aggagaattt gcaagataga atttgcaatt tgcaagaggg
     5221 aattgcaatt tgcaagagag gggcaatttg caatttgcaa gagagggcaa tttgcaagag
     5281 agaattgtgg ggccctgaga gagaatacat ccaaaggaag agggaaccag gcattacaaa
     5341 ttgaattgaa caaggacaga tatctgaagg gggtttgtag ttcccagtaa agtatggtac
     5401 agctaggtgc acttccctgg ccagaccacc ctacagtgta tgatccccct ggggagcaaa
     5461 aggctgcagg taacactttg gtgccctaga aattctgctg tggtgcaact atagtggatc
     5521 acaggcagag tggggcattg ttccccttct tagcacagga tactgggtca tttcaacacc
     5581 acaaggattt gcagcatctg cggcaacgag tttggtgtcc tggagcaagg aaaggaaccg
     5641 ttcatggtgg ctgaagccaa gctgctcagc actgaggcag caagccatga tctaggtctt
     5701 cgagtagaat tctcagtttt ggttcattta aaaatgtttt ttgggggaat tggggatcat
     5761 ttatgggtac caaaagaaaa aaaaatgaat aagatctact atttgatagc acaatagggt
     5821 gactatagtc aataataaca attgtatatt ttaaaataaa gaatgtaatt gaaaagagta
     5881 aatgcctgag gggatggata ccccattctc tgtgatgtgc ttatttcaca ttgcatgcct
     5941 gtatcaaaat atctcatgta ccccataaat atatgcacct actatgtacc cacaactatt
     6001 taaaaaataa taaaatttta aaaaattgtc
//
