LOCUS       NM_022346               4587 bp    mRNA    linear   PRI 23-MAR-2024
DEFINITION  Homo sapiens non-SMC condensin I complex subunit G (NCAPG),
            transcript variant 1, mRNA.
ACCESSION   NM_022346
VERSION     NM_022346.5
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 4587)
  AUTHORS   Zhu,Q.H., Zhou,Y.L., Yang,M., Yang,B.B., Cao,W.T., Yuan,L.M. and
            Deng,D.Q.
  TITLE     Reduced miR-99a-3p levels in systemic lupus erythematosus may
            promote B cell proliferation via NCAPG and the PI3K/AKT signaling
            pathway
  JOURNAL   Lupus 33 (4), 365-374 (2024)
   PUBMED   38320572
  REMARK    GeneRIF: Reduced miR-99a-3p levels in systemic lupus erythematosus
            may promote B cell proliferation via NCAPG and the PI3K/AKT
            signaling pathway.
REFERENCE   2  (bases 1 to 4587)
  AUTHORS   Zheng,T., Qian,T., Zhou,H., Cheng,Z., Liu,G., Huang,C., Dou,R.,
            Liu,F. and You,X.
  TITLE     Galectin-1-mediated high NCAPG expression correlates with poor
            prognosis in gastric cancer
  JOURNAL   Aging (Albany NY) 15 (12), 5535-5549 (2023)
   PUBMED   37335105
  REMARK    GeneRIF: Galectin-1-mediated high NCAPG expression correlates with
            poor prognosis in gastric cancer.
REFERENCE   3  (bases 1 to 4587)
  AUTHORS   Lin,J., Li,G., Bai,Y. and Xie,Y.
  TITLE     NCAPG as a novel prognostic biomarker in numerous cancers: a
            meta-analysis and bioinformatics analysis
  JOURNAL   Aging (Albany NY) 15 (7), 2503-2524 (2023)
   PUBMED   36996493
  REMARK    GeneRIF: NCAPG as a novel prognostic biomarker in numerous cancers:
            a meta-analysis and bioinformatics analysis.
REFERENCE   4  (bases 1 to 4587)
  AUTHORS   Li,H., Jiang,Y., Hu,J., Xu,J., Chen,L., Zhang,G., Zhao,J., Zong,S.,
            Guo,Z., Li,X., Zhao,X. and Jing,Z.
  TITLE     The U2AF65/circNCAPG/RREB1 feedback loop promotes malignant
            phenotypes of glioma stem cells through activating the TGF-beta
            pathway
  JOURNAL   Cell Death Dis 14 (1), 23 (2023)
   PUBMED   36635261
  REMARK    GeneRIF: The U2AF65/circNCAPG/RREB1 feedback loop promotes
            malignant phenotypes of glioma stem cells through activating the
            TGF-beta pathway.
            Publication Status: Online-Only
REFERENCE   5  (bases 1 to 4587)
  AUTHORS   Zhang,L., Ma,T., Yan,Y., Chen,Y.Y., Zhu,X.H. and Ren,H.Z.
  TITLE     The Diagnostic and Therapeutic Value of NCAPG as a Proposed
            Biomarker Candidate in Acute Liver Failure
  JOURNAL   Comb Chem High Throughput Screen 26 (15), 2738-2748 (2023)
   PUBMED   37066775
  REMARK    GeneRIF: The Diagnostic and Therapeutic Value of NCAPG as a
            Proposed Biomarker Candidate in Acute Liver Failure.
REFERENCE   6  (bases 1 to 4587)
  AUTHORS   Xing,H., Wilkerson,D.C., Mayhew,C.N., Lubert,E.J., Skaggs,H.S.,
            Goodson,M.L., Hong,Y., Park-Sarge,O.K. and Sarge,K.D.
  TITLE     Mechanism of hsp70i gene bookmarking
  JOURNAL   Science 307 (5708), 421-423 (2005)
   PUBMED   15662014
REFERENCE   7  (bases 1 to 4587)
  AUTHORS   Geiman,T.M., Sankpal,U.T., Robertson,A.K., Chen,Y., Mazumdar,M.,
            Heale,J.T., Schmiesing,J.A., Kim,W., Yokomori,K., Zhao,Y. and
            Robertson,K.D.
  TITLE     Isolation and characterization of a novel DNA methyltransferase
            complex linking DNMT3B with components of the mitotic chromosome
            condensation machinery
  JOURNAL   Nucleic Acids Res 32 (9), 2716-2729 (2004)
   PUBMED   15148359
  REMARK    Publication Status: Online-Only
REFERENCE   8  (bases 1 to 4587)
  AUTHORS   Ball,A.R. Jr., Schmiesing,J.A., Zhou,C., Gregson,H.C., Okada,Y.,
            Doi,T. and Yokomori,K.
  TITLE     Identification of a chromosome-targeting domain in the human
            condensin subunit CNAP1/hCAP-D2/Eg7
  JOURNAL   Mol Cell Biol 22 (16), 5769-5781 (2002)
   PUBMED   12138188
REFERENCE   9  (bases 1 to 4587)
  AUTHORS   Kimura,K., Cuvier,O. and Hirano,T.
  TITLE     Chromosome condensation by a human condensin complex in Xenopus egg
            extracts
  JOURNAL   J Biol Chem 276 (8), 5417-5420 (2001)
   PUBMED   11136719
REFERENCE   10 (bases 1 to 4587)
  AUTHORS   Jager,D., Stockert,E., Jager,E., Gure,A.O., Scanlan,M.J., Knuth,A.,
            Old,L.J. and Chen,Y.T.
  TITLE     Serological cloning of a melanocyte rab guanosine
            5'-triphosphate-binding protein and a chromosome condensation
            protein from a melanoma complementary DNA library
  JOURNAL   Cancer Res 60 (13), 3584-3591 (2000)
   PUBMED   10910072
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from DB451361.1, AC005768.17,
            AF331796.1 and BG398543.1.
            
            On Nov 23, 2018 this sequence version replaced NM_022346.4.
            
            Summary: This gene encodes a subunit of the condensin complex,
            which is responsible for the condensation and stabilization of
            chromosomes during mitosis and meiosis. Phosphorylation of the
            encoded protein activates the condensin complex. There are
            pseudogenes for this gene on chromosomes 8 and 15. Alternative
            splicing results in multiple transcript variants. [provided by
            RefSeq, Aug 2012].
            
            Transcript Variant: This variant (1) represents the longer
            transcript and encodes the protein.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1163658.448405.1, AB013299.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1965299, SAMEA1966682
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000251496.7/ ENSP00000251496.2
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-13                DB451361.1         167-179
            14-14               AC005768.17        76723-76723         c
            15-3231             AF331796.1         92-3308
            3232-4332           AC005768.17        43105-44205         c
            4333-4587           BG398543.1         133-387
FEATURES             Location/Qualifiers
     source          1..4587
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="4"
                     /map="4p15.31"
     gene            1..4587
                     /gene="NCAPG"
                     /gene_synonym="CAPG; CHCG; NY-MEL-3; YCG1"
                     /note="non-SMC condensin I complex subunit G"
                     /db_xref="GeneID:64151"
                     /db_xref="HGNC:HGNC:24304"
                     /db_xref="MIM:606280"
     exon            1..210
                     /gene="NCAPG"
                     /gene_synonym="CAPG; CHCG; NY-MEL-3; YCG1"
                     /inference="alignment:Splign:2.1.0"
     CDS             100..3147
                     /gene="NCAPG"
                     /gene_synonym="CAPG; CHCG; NY-MEL-3; YCG1"
                     /note="chromosome condensation protein G; XCAP-G homolog;
                     condensin subunit CAP-G; melanoma antigen NY-MEL-3;
                     chromosome-associated protein G"
                     /codon_start=1
                     /product="condensin complex subunit 3"
                     /protein_id="NP_071741.2"
                     /db_xref="CCDS:CCDS3424.1"
                     /db_xref="GeneID:64151"
                     /db_xref="HGNC:HGNC:24304"
                     /db_xref="MIM:606280"
                     /translation="MGAERRLLSIKEAFRLAQQPHQNQAKLVVALSRTYRTMDDKTVF
                     HEEFIHYLKYVMVVYKREPAVERVIEFAAKFVTSFHQSDMEDDEEEEDGGLLNYLFTF
                     LLKSHEANSNAVRFRVCLLINKLLGSMPENAQIDDDVFDKINKAMLIRLKDKIPNVRI
                     QAVLALSRLQDPKDDECPVVNAYATLIENDSNPEVRRAVLSCIAPSAKTLPKIVGRTK
                     DVKEAVRKLAYQVLAEKVHMRAMSIAQRVMLLQQGLNDRSDAVKQAMQKHLLQGWLRF
                     SEGNILELLHRLDVENSSEVAVSVLNALFSITPLSELVGLCKNNDGRKLIPVETLTPE
                     IALYWCALCEYLKSKGDEGEEFLEQILPEPVVYADYLLSYIQSIPVVNEEHRGDFSYI
                     GNLMTKEFIGQQLILIIKSLDTSEEGGRKKLLAVLQEILILPTIPISLVSFLVERLLH
                     IIIDDNKRTQIVTEIISEIRAPIVTVGVNNDPADVRKKELKMAEIKVKLIEAKEALEN
                     CITLQDFNRASELKEEIKALEDARINLLKETEQLEIKEVHIEKNDAETLQKCLILCYE
                     LLKQMSISTGLSATMNGIIESLILPGIISIHPVVRNLAVLCLGCCGLQNQDFARKHFV
                     LLLQVLQIDDVTIKISALKAIFDQLMTFGIEPFKTKKIKTLHCEGTEINSDDEQESKE
                     VEETATAKNVLKLLSDFLDSEVSELRTGAAEGLAKLMFSGLLVSSRILSRLILLWYNP
                     VTEEDVQLRHCLGVFFPVFAYASRTNQECFEEAFLPTLQTLANAPASSPLAEIDITNV
                     AELLVDLTRPSGLNPQAKTSQDYQALTVHDNLAMKICNEILTSPCSPEIRVYTKALSS
                     LELSSHLAKDLLVLLNEILEQVKDRTCLRALEKIKIQLEKGNKEFGDQAEAAQDATLT
                     TTTFQNEDEKNKEVYMTPLRGVKATQASKSTQLKTNRGQRKVTVSARTNRRCQTAEAD
                     SESDHEVPEPESEMKMRLPRRAKTAALEKSKLNLAQFLNEDLS"
     exon            211..414
                     /gene="NCAPG"
                     /gene_synonym="CAPG; CHCG; NY-MEL-3; YCG1"
                     /inference="alignment:Splign:2.1.0"
     exon            415..643
                     /gene="NCAPG"
                     /gene_synonym="CAPG; CHCG; NY-MEL-3; YCG1"
                     /inference="alignment:Splign:2.1.0"
     exon            644..789
                     /gene="NCAPG"
                     /gene_synonym="CAPG; CHCG; NY-MEL-3; YCG1"
                     /inference="alignment:Splign:2.1.0"
     exon            790..874
                     /gene="NCAPG"
                     /gene_synonym="CAPG; CHCG; NY-MEL-3; YCG1"
                     /inference="alignment:Splign:2.1.0"
     exon            875..1067
                     /gene="NCAPG"
                     /gene_synonym="CAPG; CHCG; NY-MEL-3; YCG1"
                     /inference="alignment:Splign:2.1.0"
     exon            1068..1217
                     /gene="NCAPG"
                     /gene_synonym="CAPG; CHCG; NY-MEL-3; YCG1"
                     /inference="alignment:Splign:2.1.0"
     exon            1218..1358
                     /gene="NCAPG"
                     /gene_synonym="CAPG; CHCG; NY-MEL-3; YCG1"
                     /inference="alignment:Splign:2.1.0"
     exon            1359..1482
                     /gene="NCAPG"
                     /gene_synonym="CAPG; CHCG; NY-MEL-3; YCG1"
                     /inference="alignment:Splign:2.1.0"
     exon            1483..1572
                     /gene="NCAPG"
                     /gene_synonym="CAPG; CHCG; NY-MEL-3; YCG1"
                     /inference="alignment:Splign:2.1.0"
     exon            1573..1752
                     /gene="NCAPG"
                     /gene_synonym="CAPG; CHCG; NY-MEL-3; YCG1"
                     /inference="alignment:Splign:2.1.0"
     exon            1753..1863
                     /gene="NCAPG"
                     /gene_synonym="CAPG; CHCG; NY-MEL-3; YCG1"
                     /inference="alignment:Splign:2.1.0"
     exon            1864..1983
                     /gene="NCAPG"
                     /gene_synonym="CAPG; CHCG; NY-MEL-3; YCG1"
                     /inference="alignment:Splign:2.1.0"
     exon            1984..2208
                     /gene="NCAPG"
                     /gene_synonym="CAPG; CHCG; NY-MEL-3; YCG1"
                     /inference="alignment:Splign:2.1.0"
     exon            2209..2390
                     /gene="NCAPG"
                     /gene_synonym="CAPG; CHCG; NY-MEL-3; YCG1"
                     /inference="alignment:Splign:2.1.0"
     exon            2391..2565
                     /gene="NCAPG"
                     /gene_synonym="CAPG; CHCG; NY-MEL-3; YCG1"
                     /inference="alignment:Splign:2.1.0"
     exon            2566..2727
                     /gene="NCAPG"
                     /gene_synonym="CAPG; CHCG; NY-MEL-3; YCG1"
                     /inference="alignment:Splign:2.1.0"
     exon            2728..2866
                     /gene="NCAPG"
                     /gene_synonym="CAPG; CHCG; NY-MEL-3; YCG1"
                     /inference="alignment:Splign:2.1.0"
     exon            2867..2953
                     /gene="NCAPG"
                     /gene_synonym="CAPG; CHCG; NY-MEL-3; YCG1"
                     /inference="alignment:Splign:2.1.0"
     exon            2954..3023
                     /gene="NCAPG"
                     /gene_synonym="CAPG; CHCG; NY-MEL-3; YCG1"
                     /inference="alignment:Splign:2.1.0"
     exon            3024..4587
                     /gene="NCAPG"
                     /gene_synonym="CAPG; CHCG; NY-MEL-3; YCG1"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3199..3204
                     /regulatory_class="polyA_signal_sequence"
                     /gene="NCAPG"
                     /gene_synonym="CAPG; CHCG; NY-MEL-3; YCG1"
                     /note="hexamer: AATAAA"
     polyA_site      3236
                     /gene="NCAPG"
                     /gene_synonym="CAPG; CHCG; NY-MEL-3; YCG1"
                     /note="major polyA site"
     regulatory      3798..3803
                     /regulatory_class="polyA_signal_sequence"
                     /gene="NCAPG"
                     /gene_synonym="CAPG; CHCG; NY-MEL-3; YCG1"
                     /note="hexamer: CATAAA"
     polyA_site      3821
                     /gene="NCAPG"
                     /gene_synonym="CAPG; CHCG; NY-MEL-3; YCG1"
     regulatory      4308..4313
                     /regulatory_class="polyA_signal_sequence"
                     /gene="NCAPG"
                     /gene_synonym="CAPG; CHCG; NY-MEL-3; YCG1"
                     /note="hexamer: AATAGA"
     polyA_site      4326
                     /gene="NCAPG"
                     /gene_synonym="CAPG; CHCG; NY-MEL-3; YCG1"
     regulatory      4569..4574
                     /regulatory_class="polyA_signal_sequence"
                     /gene="NCAPG"
                     /gene_synonym="CAPG; CHCG; NY-MEL-3; YCG1"
                     /note="hexamer: AATAAA"
     polyA_site      4587
                     /gene="NCAPG"
                     /gene_synonym="CAPG; CHCG; NY-MEL-3; YCG1"
ORIGIN      
        1 gtcatagaag actactcgga gagcgctgcc tctgggttgg cgggctggca ggctgtagcc
       61 gagcgcgggc aggactcgtc ccggcagggt tccagagcca tgggagcgga aaggaggctg
      121 ctgtcgatta aggaggcctt tcggctggcg cagcagccgc accagaacca ggcgaagctg
      181 gtggtggcgc tgagccgcac ctaccgcacg atggatgata agacagtttt tcatgaggag
      241 ttcattcatt accttaaata tgttatggtg gtctataaac gtgaaccagc tgtggagagg
      301 gtaatagaat ttgcagcaaa gtttgttacc tcatttcacc aatcagatat ggaagatgat
      361 gaggaagagg aagatggtgg ccttttaaat tatttgttta cttttctctt aaagtctcat
      421 gaagcaaaca gcaatgcagt gagatttaga gtgtgcctgc tcataaacaa gcttttggga
      481 agtatgccag aaaatgctca gattgatgat gatgtgtttg ataaaattaa taaagccatg
      541 cttattagat tgaaagataa gattccaaat gtgagaatac aggcagttct ggcgctttca
      601 cgacttcagg atcccaagga tgatgaatgc ccagtggtta atgcatatgc tactttgatt
      661 gaaaatgatt caaatccaga agttagacgg gcagtgttat catgtattgc accatcagca
      721 aagactttgc caaaaattgt agggcgcacc aaggatgtga aagaggctgt cagaaagctg
      781 gcttatcagg ttttagctga aaaggttcat atgagagcta tgtccattgc tcagagagta
      841 atgctccttc aacaaggtct taatgacaga tcagatgctg tgaaacaagc tatgcagaag
      901 catcttcttc aaggctggtt acggttctct gaaggaaata tcttagagtt gctccatcgg
      961 ttggatgtag aaaattcttc tgaagtggca gtctctgttc tcaatgcctt gttttcaata
     1021 actcctctca gtgaactggt gggactctgt aaaaacaatg atggcaggaa attgattcca
     1081 gtggaaacat taactcctga aattgctttg tattggtgtg ccctttgtga atatttgaaa
     1141 tcaaaaggag atgaaggtga agaattttta gagcagattt tgccagagcc tgtagtatat
     1201 gcagactatt tattgagtta catccagagc attccagttg ttaatgaaga acacagaggt
     1261 gatttttcct atattggaaa tttgatgaca aaagaattca taggtcaaca attgattcta
     1321 attattaagt ctttggatac cagtgaagaa ggaggaagaa aaaaactgct ggctgtttta
     1381 caggagattc ttattttacc cacaatccca atatccctgg tttcttttct tgttgaaaga
     1441 ctactccaca tcattataga tgataataag agaacacaaa ttgttacaga aattatctca
     1501 gagattcggg cgcccattgt tactgttggt gttaataacg atccagctga tgtaagaaag
     1561 aaagaactca agatggctga aataaaagtt aagcttatcg aagccaaaga agctttggaa
     1621 aattgcatta ccttacagga ttttaatcgg gcatcagaat taaaagaaga aataaaagca
     1681 ttagaagatg ccagaataaa ccttttgaaa gagacagagc aacttgaaat taaagaagtc
     1741 cacatagaga agaatgatgc tgaaacattg cagaaatgtc ttattttatg ctatgaactg
     1801 ttgaagcaga tgtccatttc aacaggctta agtgcaacca tgaatggaat catcgaatct
     1861 ttgattcttc ctggaataat aagtattcat cctgttgtaa gaaacctggc tgttttatgc
     1921 ttgggatgct gtggactaca gaatcaggat tttgcaagga aacacttcgt attactattg
     1981 caggttttgc aaattgatga tgtcacaata aaaataagtg ctttaaaggc aatctttgac
     2041 caactgatga cgttcgggat tgaaccattt aaaactaaaa aaatcaaaac acttcattgt
     2101 gaaggtacag aaataaacag tgatgatgag caagaatcaa aagaagttga agagactgct
     2161 acagctaaga atgttctgaa actcctttct gatttcttag atagtgaggt atctgaactt
     2221 aggactggag ctgcagaagg actagccaag ctgatgttct ctgggctttt ggtcagcagc
     2281 aggattcttt ctcgtcttat tttgttatgg tacaatcctg tgactgaaga ggatgttcaa
     2341 cttcgacatt gcctaggcgt gttcttcccc gtgtttgctt atgcaagcag gactaatcag
     2401 gaatgctttg aagaagcttt tcttccaacc ctgcaaacac tggccaatgc ccctgcatct
     2461 tctcctttag ctgaaattga tatcacaaat gttgctgagt tacttgtaga tttgacaaga
     2521 ccaagtggat taaatcctca ggccaagact tcccaagatt atcaggcctt aacagtacat
     2581 gacaatttgg ctatgaaaat ttgcaatgag atcttaacaa gtccgtgctc gccagaaatt
     2641 cgagtctata caaaagcctt gagttcttta gaactcagta gccatcttgc aaaagatctt
     2701 ctggttctat tgaatgagat tctggagcaa gtaaaagata ggacatgtct gagagctttg
     2761 gagaaaatca agattcagtt agaaaaagga aataaagaat ttggtgacca agctgaagca
     2821 gcacaggatg ccaccttgac tacaactact ttccaaaatg aagatgaaaa gaataaagaa
     2881 gtatatatga ctccactcag gggtgtaaaa gcaacccaag catcaaagtc tactcagcta
     2941 aagactaaca gaggacagag aaaagtgaca gtttcagcta ggacgaacag gaggtgtcag
     3001 actgctgaag ccgactctga aagtgatcat gaagttccag aaccagaatc agaaatgaag
     3061 atgagactac caagacgagc caaaaccgca gcactagaaa aaagtaaact taaccttgcc
     3121 caatttctca atgaagatct aagttaggaa agacgatgga ggtggaatcc tttaagatta
     3181 tgtccagtta tttgctttaa taaagaagaa gttacccttg tcaaaatcag aacaaacctg
     3241 atgtctttct gaagattttc tgctgtgcgc ttccacgtta ctttggcctg tattaaagca
     3301 gtagagcagc atcagttatt atagtccaga aaaagtgtgc atcagtcagt cacacagatt
     3361 tatcacaatc tgaggtgggc ctaggaatct catttttaaa tagtctctcc aagtgattct
     3421 tatgaactct ttatgtttaa aatcatgtca ttatggaaaa cttacaagtg taactagcta
     3481 gtagcttgca tttgagaagc ttatgactta gatgggcaga atcaacaaag atgaaaccgc
     3541 ctgaggacac atttaacaag taacatttct agggaaaatg aaggaagtac cacaaactgg
     3601 ctagaaagga gcttatcaat caccagtgag gaagaccagt ataacgttca acaacagtta
     3661 ttttgacaaa aacttatttt gtgattccta cagtgaaaac atttttggtg atatctgcct
     3721 gggaaatctc tcttcctaaa gtatttgtat atgggagtcc ttgtttgtga atgtttcctg
     3781 gattagggag gtgtcaacat aaatgtatta ttaaccatga agctgctcgc tatatttttg
     3841 gcataacaaa ataatattta tttactgtgg ataataattc tagtgggaat ataatgtgac
     3901 aggaacttct ctttatatac gctaccaatt tatgagcact attcactgtc aatttcattt
     3961 cttgtctttt gaaattgaca cttggcctga cttacgaaac ttgtactata tgaaattggt
     4021 cctcttttct gcaataccca acgaaacacc ttttctcttt attattcaga aatgtcctaa
     4081 catggatctg tttgttttaa taattgtgct ttttttaggc ttatcatcta ctagaggcca
     4141 tttacttaag gtgaaatttt aagatggagc taaagtaaga tcactggttt ttagaaccaa
     4201 attgctatac atatgtgcct catagaactt ataaaaggag tcaaagtttc aaagcaagat
     4261 agttattaag caaaaggaaa aatggtaatg atagaaagtc agttaaaaat agatgattgt
     4321 tcttcattct gtttgttggc tctgtgttct cctgtgcttc agattcctta tgtgttgttg
     4381 ttttaaagac aatttgcagg gggttgggag aaggactgaa aaggtacatt aagtgtgctg
     4441 taaggaaaag tcttagaaac ataataagct aaaatcccat tcacacatgg ccaggctatc
     4501 caaaaagaaa ggagccatgt tctcatgtgg tttaccatac caaagcttgc tttctctggc
     4561 atgggaaaaa taaatttaag caccaaa
//
