LOCUS       XM_047436061            5414 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens NBR1 autophagy cargo receptor (NBR1),
            transcript variant X3, mRNA.
ACCESSION   XM_047436061
VERSION     XM_047436061.1
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000017.11) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5414
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="17"
     gene            1..5414
                     /gene="NBR1"
                     /gene_synonym="1A1-3B; IAI3B; M17S2; MIG19"
                     /note="NBR1 autophagy cargo receptor; Derived by automated
                     computational analysis using gene prediction method:
                     Gnomon. Supporting evidence includes similarity to: 2
                     mRNAs, 99 ESTs, 1807 long SRA reads, 4 Proteins, and 100%
                     coverage of the annotated genomic feature by RNAseq
                     alignments, including 84 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:4077"
                     /db_xref="HGNC:HGNC:6746"
                     /db_xref="MIM:166945"
     CDS             900..3800
                     /gene="NBR1"
                     /gene_synonym="1A1-3B; IAI3B; M17S2; MIG19"
                     /codon_start=1
                     /product="next to BRCA1 gene 1 protein isoform X1"
                     /protein_id="XP_047292017.1"
                     /db_xref="GeneID:4077"
                     /db_xref="HGNC:HGNC:6746"
                     /db_xref="MIM:166945"
                     /translation="MEPQVTLNVTFKNEIQSFLVSDPENTTWADIEAMVKVSFDLNTI
                     QIKYLDEENEEVSINSQGEYEEALKMAVKQGNQLQMQVHEGHHVVDEAPPPVVGAKRL
                     AARAGKKPLAHYSSLVRVLGSDMKTPEDPAVQSFPLVPCDTDQPQDKPPDWFTSYLET
                     FREQVVNETVEKLEQKLHEKLVLQNPSLGSCPSEVSMPTSEETLFLPENQFSWHIACN
                     NCQRRIVGVRYQCSLCPSYNICEDCEAGPYGHDTNHVLLKLRRPVVGSSEPFCHSKYS
                     TPRLPAALEQVRLQKQVDKNFLKAEKQRLRAEKKQRKAEVKELKKQLKLHRKIHLWNS
                     IHGLQSPKSPLGRPESLLQSNTLMLPLQPCTSVMPMLSAAFVDENLPDGTHLQPGTKF
                     IKHWRMKNTGNVKWSADTKLKFMWGNLTLASTEKKDVLVPCLKAGHVGVVSVEFIAPA
                     LEGTYTSHWRLSHKGQQFGPRVWCSIIVDPFPSEESPDNIEKGMISSSKTDDLTCQQE
                     ETFLLAKEERQLGEVTEQTEGTAACIPQKAKNVASERELYIPSVDLLTAQDLLSFELL
                     DINIVQELERVPHNTPVDVTPCMSPLPHDSPLIEKPGLGQIEEENEGAGFKALPDSMV
                     SVKRKAENIASVEEAEEDLSGTQFVCETVIRSLTLDAAPDHNPPCRQKSLQMTFALPE
                     GPLGNEKEEIIHIAEEEAVMEEEEDEEDEEEEDELKDEVQSQSSASSEDYIIILPECF
                     DTSRPLGDSMYSSALSQPGLERGAEGKPGVEAGQEPAEAGERLPGGENQPQEHSISDI
                     LTTSQTLETVPLIPEVVELPPSLPRSSPCVHHHGSPGVDLPVTIPEVSSVPDQIRGEP
                     RGSSGLVNSRQKSYDHSRHHHGSSIAGGLVKGALSVAASAYKALFAGPPVTAQPIISE
                     DQTAALMAHLFEMGFCDRQLNLRLLKKHNYNILQVVTELLQLNNNDWYSQRY"
ORIGIN      
        1 agattcaccc cacagggata gcggcagagc cggtagcgga cggtccttgc attggcctcc
       61 ggcaggcgcc ccccgggggc gggaagctgg taaggaagca gctgcggtta cctaggggtg
      121 gggtcacgtc acgctaagag ggtttgggga agttcaaggg aggaatcctg caaagaagag
      181 gggcgacttt ttccgtgttt cgggacagct aatcttttta gtgacaggat gagagagccc
      241 ttcatgttca gagggaccga gttggcgaga agcgccggag agttggagag tctgtgggtc
      301 agaacatccg gcttctactg atggaaggcc acgactcccc agtggaatga gggcctaggc
      361 aaagaaaatg agagagccct cggggtagtg acactgtctt gggaacatgg agtgctagga
      421 aacgaaaact ggaagactag gatgaactct gcaagtaaaa aaatgacact acttacacat
      481 ccttctcatc ccatcctcgt tttttcgaga ccttaaagag atctccttgg ttagggacct
      541 tcggttttgg aaaggcactg tttttccttt ttgtcaaaca ctcagctttc aggccacact
      601 tttttgagac agagtcttgc tttctcaaag accaacccag gctgggcttg aactgctgag
      661 ctcaagcgat cctcgtgcct tggcctccca aagtgctggg attacaggta taagccaccg
      721 ctcccggcct caggtcacac attttaaagc ctggataact tggcttgtaa aggcctctgg
      781 tggagacagt aatcaaagct caggttgcca ggtctgtttc attaaaggga ttttgttgag
      841 gctgaaaaaa aaatcgacgt ggaggaaaag ctaacttgtg ccaagcaaag cctcacagca
      901 tggaaccaca ggttactcta aatgtgactt ttaaaaatga aattcaaagc tttctggttt
      961 ctgatccaga aaatacaact tgggctgata tcgaagctat ggtaaaagtt tcatttgatc
     1021 tgaatactat tcaaataaaa tacctggatg aggaaaatga agaggtatcc atcaacagtc
     1081 aaggagaata tgaagaagcg cttaagatgg cagttaaaca gggaaaccaa ctgcagatgc
     1141 aagtccacga agggcaccat gtcgttgatg aagccccacc cccagttgta ggagcaaaac
     1201 gactagctgc cagggcaggg aagaagccac ttgcacatta ctcttcactg gtgagagtct
     1261 tgggatcaga catgaagacc ccagaggatc ctgcagtgca gtcgtttcca cttgttccat
     1321 gtgacacaga ccagcctcaa gacaagcccc cagactggtt cacaagctac ctggagacgt
     1381 tcagagaaca agtggttaac gaaacggttg agaagcttga acagaaatta catgaaaagc
     1441 ttgtcctcca gaacccatcc ttgggttctt gtccctcaga agtctcaatg cctacttcag
     1501 aagaaacatt gtttttgcca gaaaaccagt tcagctggca tattgcttgc aacaactgcc
     1561 aaagaaggat tgttggtgtc cgctaccagt gtagcctatg cccatcctac aatatctgtg
     1621 aagattgtga agcagggcca tatggccatg acactaacca cgtcctgctg aagttgcgga
     1681 gacctgttgt gggctcctct gaaccgttct gtcactcaaa gtactctact cctcgtcttc
     1741 ctgctgctct ggaacaagtc aggctccaga aacaggttga taagaacttt cttaaagcag
     1801 aaaagcaaag gttgcgagct gagaagaaac aacgtaaagc agaggtcaag gaacttaaaa
     1861 agcagcttaa actccatagg aaaattcacc tgtggaattc aatccatgga ctccagagcc
     1921 ccaagtctcc tttaggccga cctgagagct tgctccagtc taataccctg atgctccctt
     1981 tgcagccctg tacctccgtt atgccaatgc tcagtgcagc atttgtggat gagaatttgc
     2041 ctgatgggac tcaccttcag ccaggaacca agtttatcaa acactggagg atgaaaaata
     2101 caggaaatgt aaagtggagt gcagacacaa agctcaagtt catgtgggga aacctgactt
     2161 tggcttccac agaaaagaag gatgttttgg ttccctgcct caaggccggc catgtgggag
     2221 ttgtatctgt ggagttcatt gccccagcct tggagggaac gtatacttcc cattggcgtc
     2281 tttctcacaa aggccagcaa tttgggcctc gggtctggtg cagtatcata gtagatcctt
     2341 tcccctccga agagagccct gataacattg aaaagggcat gatcagctca agcaaaactg
     2401 atgatctcac ctgccagcaa gaggaaactt ttcttctggc taaagaagaa agacagcttg
     2461 gtgaagtgac tgagcagaca gaagggacag cagcctgcat cccacagaag gcaaaaaatg
     2521 ttgccagtga gagggagctc tacatcccat ctgtggatct tctgactgcc caggacctgc
     2581 tgtcctttga gctgttggat ataaacattg ttcaagagtt ggagagagtg ccccacaaca
     2641 cccctgtgga tgtgactccc tgcatgtctc ctctgccaca tgacagtcct ttaatagaga
     2701 agccaggctt ggggcagata gaggaagaga atgaaggggc aggatttaaa gcacttcctg
     2761 attctatggt gtcagtaaag aggaaggctg agaacattgc ttctgtggag gaagcagaag
     2821 aagacctgag tgggacccag tttgtgtgtg agacagtaat ccgatccctt accttggatg
     2881 ctgccccaga ccacaaccct ccttgcagac agaagtcctt gcagatgaca tttgccttgc
     2941 ctgaaggacc acttggaaat gagaaggagg agattatcca tatcgctgag gaagaagctg
     3001 tcatggagga ggaggaggat gaggaggatg aggaggagga ggatgagctc aaagatgaag
     3061 ttcaaagtca gtcctctgct tcctcagagg attacatcat catcctgcct gagtgctttg
     3121 ataccagccg ccccctgggg gattctatgt acagctctgc gctctcacag ccaggcctgg
     3181 agcgaggtgc tgaaggcaag cctggggttg aggctgggca ggaaccagct gaggctgggg
     3241 aaagactccc tggaggggag aaccagccac aggagcacag cataagtgac atcctcacga
     3301 cctcacagac tctggaaaca gtgcccctaa tcccagaggt agtggagctt ccaccgtcac
     3361 tgcccaggag ctctccttgt gtacatcatc atggttcccc aggagtggat ttaccagtta
     3421 ccataccaga agtttcttca gtccctgatc agatcagagg agagcccaga ggctcatcag
     3481 gacttgtaaa cagcagacag aagagctatg accactcaag gcaccatcat gggagcagca
     3541 ttgctggagg actggtgaag ggggctttgt ctgttgctgc ctctgcatac aaggccctgt
     3601 ttgctgggcc accagtcact gcacagccaa taatttctga agatcagaca gcagccctga
     3661 tggcccatct ctttgaaatg ggattctgtg acaggcagct gaacctacgg ctgctgaaga
     3721 aacacaatta caatatcctg caggttgtga cagaacttct tcagttaaac aacaacgact
     3781 ggtacagcca acgctattga ggagtgacct tgtattaaat aactgcctgc tgctcagaga
     3841 tgatctttat tctgtcattg gggtatggga tagaagccct tgcttatttt taatctgatg
     3901 aatctgtata gagcccatcg ttgagttacc aagacaatac ctgctacagt attttgggga
     3961 gcaaactaaa gaccagaact taaattttca ctttagacat tggatgaata gtatgaagac
     4021 agtttttcag ttgatttgga taaaactatt ttagtgcatt gacaagtgta acttcaactt
     4081 catatagaac catttttctt tctgctttta ttgaaactga gtatttttct ttggctaatg
     4141 tggatttttt atggggatat ctgttaattt tcaggttttg aaagacatta acctcggaag
     4201 ttgtttttaa gaattattct cataattctt attctcataa tttctgtaat ccacctcaag
     4261 cttcatagtt atttggcatt gaaataacac ccagagcatg atagaaatgt tgttactctt
     4321 cctctctcaa ggagaaagta attttcctgc aatacttaat aattggcacc gttgctttct
     4381 aaagactcca tggtgcattc aagagtatcc aacttcaagg gaatctccgc atttcaatga
     4441 aaggaggaag agtgtgctga taaacctacc agcacctatt gagcaatgtc tattatagta
     4501 attttgcata catttttatt taagggaaaa aatataggta ttgtgaaata ttttgctaat
     4561 cttatagaaa aggaaaaaat cccgttattt aaagggaaaa gtaaatttaa cagttgcctt
     4621 ttttcttaat gtcagggcag atcttatttt acagtacagt gggggaaata gaaacatgtg
     4681 aaaggcaaaa ggcaggctcc taaattaatg tcagtgaagt tcagggtggg caaatgagtg
     4741 tgtgtgaggt ataggaaatg ctgatgactt ctttaatgct tgaagtccgt tcacaggtat
     4801 ctagccctag aatgcctaga acaggaagag gcagctggtg ttctgcaaaa cttggacagg
     4861 ggcaaagttg ctgaaaaagt tttggtttaa cccgaagata agtggaaaag agcttgtcca
     4921 tgaacccagg ttctcactct gtttacagaa gtgtgttgag tacagttggt gaaggaagag
     4981 gtaacaaaaa atgctaaata ttttatccat gaaaatgact tccagaaaag gaagaatatg
     5041 aaccccagac cgaaggggaa aagatagtta atagtattat ctaacctggt tggtatttgt
     5101 aatgaatggt gattttaatt agtcattagc cataatgatg tttatttaca gtataactcc
     5161 tgaatgctac ttaaataaac caggattcaa actgcaagcc agccaggccg ttcattattt
     5221 aaaacgtttt aatcggggct tccgggtaga aggtggagcg gcagggtgta attgggttga
     5281 tgggtgggac ctgtcttgac catcggagtt ttataatcga gggccaggag ggcccgggtt
     5341 gctctcctgg ttatgtatgt acttgtacat aaccacctaa agaatggtga aataaatgtt
     5401 cttggaaatt ccta
//
