LOCUS       XM_024450749            4614 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens NBR1 autophagy cargo receptor (NBR1),
            transcript variant X2, mRNA.
ACCESSION   XM_024450749
VERSION     XM_024450749.2
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000017.11) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Apr 5, 2022 this sequence version replaced XM_024450749.1.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4614
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="17"
     gene            1..4614
                     /gene="NBR1"
                     /gene_synonym="1A1-3B; IAI3B; M17S2; MIG19"
                     /note="NBR1 autophagy cargo receptor; Derived by automated
                     computational analysis using gene prediction method:
                     Gnomon. Supporting evidence includes similarity to: 2
                     mRNAs, 100 ESTs, 1808 long SRA reads, 4 Proteins, and 100%
                     coverage of the annotated genomic feature by RNAseq
                     alignments, including 46 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:4077"
                     /db_xref="HGNC:HGNC:6746"
                     /db_xref="MIM:166945"
     CDS             100..3000
                     /gene="NBR1"
                     /gene_synonym="1A1-3B; IAI3B; M17S2; MIG19"
                     /codon_start=1
                     /product="next to BRCA1 gene 1 protein isoform X1"
                     /protein_id="XP_024306517.1"
                     /db_xref="GeneID:4077"
                     /db_xref="HGNC:HGNC:6746"
                     /db_xref="MIM:166945"
                     /translation="MEPQVTLNVTFKNEIQSFLVSDPENTTWADIEAMVKVSFDLNTI
                     QIKYLDEENEEVSINSQGEYEEALKMAVKQGNQLQMQVHEGHHVVDEAPPPVVGAKRL
                     AARAGKKPLAHYSSLVRVLGSDMKTPEDPAVQSFPLVPCDTDQPQDKPPDWFTSYLET
                     FREQVVNETVEKLEQKLHEKLVLQNPSLGSCPSEVSMPTSEETLFLPENQFSWHIACN
                     NCQRRIVGVRYQCSLCPSYNICEDCEAGPYGHDTNHVLLKLRRPVVGSSEPFCHSKYS
                     TPRLPAALEQVRLQKQVDKNFLKAEKQRLRAEKKQRKAEVKELKKQLKLHRKIHLWNS
                     IHGLQSPKSPLGRPESLLQSNTLMLPLQPCTSVMPMLSAAFVDENLPDGTHLQPGTKF
                     IKHWRMKNTGNVKWSADTKLKFMWGNLTLASTEKKDVLVPCLKAGHVGVVSVEFIAPA
                     LEGTYTSHWRLSHKGQQFGPRVWCSIIVDPFPSEESPDNIEKGMISSSKTDDLTCQQE
                     ETFLLAKEERQLGEVTEQTEGTAACIPQKAKNVASERELYIPSVDLLTAQDLLSFELL
                     DINIVQELERVPHNTPVDVTPCMSPLPHDSPLIEKPGLGQIEEENEGAGFKALPDSMV
                     SVKRKAENIASVEEAEEDLSGTQFVCETVIRSLTLDAAPDHNPPCRQKSLQMTFALPE
                     GPLGNEKEEIIHIAEEEAVMEEEEDEEDEEEEDELKDEVQSQSSASSEDYIIILPECF
                     DTSRPLGDSMYSSALSQPGLERGAEGKPGVEAGQEPAEAGERLPGGENQPQEHSISDI
                     LTTSQTLETVPLIPEVVELPPSLPRSSPCVHHHGSPGVDLPVTIPEVSSVPDQIRGEP
                     RGSSGLVNSRQKSYDHSRHHHGSSIAGGLVKGALSVAASAYKALFAGPPVTAQPIISE
                     DQTAALMAHLFEMGFCDRQLNLRLLKKHNYNILQVVTELLQLNNNDWYSQRY"
ORIGIN      
        1 attctacctg agttcgccgt aaagcgcccg ccctctcgcc tctacgcttc cagttgcggc
       61 ttattacgtc acagtaattg ctgtaccaag cctcacagca tggaaccaca ggttactcta
      121 aatgtgactt ttaaaaatga aattcaaagc tttctggttt ctgatccaga aaatacaact
      181 tgggctgata tcgaagctat ggtaaaagtt tcatttgatc tgaatactat tcaaataaaa
      241 tacctggatg aggaaaatga agaggtatcc atcaacagtc aaggagaata tgaagaagcg
      301 cttaagatgg cagttaaaca gggaaaccaa ctgcagatgc aagtccacga agggcaccat
      361 gtcgttgatg aagccccacc cccagttgta ggagcaaaac gactagctgc cagggcaggg
      421 aagaagccac ttgcacatta ctcttcactg gtgagagtct tgggatcaga catgaagacc
      481 ccagaggatc ctgcagtgca gtcgtttcca cttgttccat gtgacacaga ccagcctcaa
      541 gacaagcccc cagactggtt cacaagctac ctggagacgt tcagagaaca agtggttaac
      601 gaaacggttg agaagcttga acagaaatta catgaaaagc ttgtcctcca gaacccatcc
      661 ttgggttctt gtccctcaga agtctcaatg cctacttcag aagaaacatt gtttttgcca
      721 gaaaaccagt tcagctggca tattgcttgc aacaactgcc aaagaaggat tgttggtgtc
      781 cgctaccagt gtagcctatg cccatcctac aatatctgtg aagattgtga agcagggcca
      841 tatggccatg acactaacca cgtcctgctg aagttgcgga gacctgttgt gggctcctct
      901 gaaccgttct gtcactcaaa gtactctact cctcgtcttc ctgctgctct ggaacaagtc
      961 aggctccaga aacaggttga taagaacttt cttaaagcag aaaagcaaag gttgcgagct
     1021 gagaagaaac aacgtaaagc agaggtcaag gaacttaaaa agcagcttaa actccatagg
     1081 aaaattcacc tgtggaattc aatccatgga ctccagagcc ccaagtctcc tttaggccga
     1141 cctgagagct tgctccagtc taataccctg atgctccctt tgcagccctg tacctccgtt
     1201 atgccaatgc tcagtgcagc atttgtggat gagaatttgc ctgatgggac tcaccttcag
     1261 ccaggaacca agtttatcaa acactggagg atgaaaaata caggaaatgt aaagtggagt
     1321 gcagacacaa agctcaagtt catgtgggga aacctgactt tggcttccac agaaaagaag
     1381 gatgttttgg ttccctgcct caaggccggc catgtgggag ttgtatctgt ggagttcatt
     1441 gccccagcct tggagggaac gtatacttcc cattggcgtc tttctcacaa aggccagcaa
     1501 tttgggcctc gggtctggtg cagtatcata gtagatcctt tcccctccga agagagccct
     1561 gataacattg aaaagggcat gatcagctca agcaaaactg atgatctcac ctgccagcaa
     1621 gaggaaactt ttcttctggc taaagaagaa agacagcttg gtgaagtgac tgagcagaca
     1681 gaagggacag cagcctgcat cccacagaag gcaaaaaatg ttgccagtga gagggagctc
     1741 tacatcccat ctgtggatct tctgactgcc caggacctgc tgtcctttga gctgttggat
     1801 ataaacattg ttcaagagtt ggagagagtg ccccacaaca cccctgtgga tgtgactccc
     1861 tgcatgtctc ctctgccaca tgacagtcct ttaatagaga agccaggctt ggggcagata
     1921 gaggaagaga atgaaggggc aggatttaaa gcacttcctg attctatggt gtcagtaaag
     1981 aggaaggctg agaacattgc ttctgtggag gaagcagaag aagacctgag tgggacccag
     2041 tttgtgtgtg agacagtaat ccgatccctt accttggatg ctgccccaga ccacaaccct
     2101 ccttgcagac agaagtcctt gcagatgaca tttgccttgc ctgaaggacc acttggaaat
     2161 gagaaggagg agattatcca tatcgctgag gaagaagctg tcatggagga ggaggaggat
     2221 gaggaggatg aggaggagga ggatgagctc aaagatgaag ttcaaagtca gtcctctgct
     2281 tcctcagagg attacatcat catcctgcct gagtgctttg ataccagccg ccccctgggg
     2341 gattctatgt acagctctgc gctctcacag ccaggcctgg agcgaggtgc tgaaggcaag
     2401 cctggggttg aggctgggca ggaaccagct gaggctgggg aaagactccc tggaggggag
     2461 aaccagccac aggagcacag cataagtgac atcctcacga cctcacagac tctggaaaca
     2521 gtgcccctaa tcccagaggt agtggagctt ccaccgtcac tgcccaggag ctctccttgt
     2581 gtacatcatc atggttcccc aggagtggat ttaccagtta ccataccaga agtttcttca
     2641 gtccctgatc agatcagagg agagcccaga ggctcatcag gacttgtaaa cagcagacag
     2701 aagagctatg accactcaag gcaccatcat gggagcagca ttgctggagg actggtgaag
     2761 ggggctttgt ctgttgctgc ctctgcatac aaggccctgt ttgctgggcc accagtcact
     2821 gcacagccaa taatttctga agatcagaca gcagccctga tggcccatct ctttgaaatg
     2881 ggattctgtg acaggcagct gaacctacgg ctgctgaaga aacacaatta caatatcctg
     2941 caggttgtga cagaacttct tcagttaaac aacaacgact ggtacagcca acgctattga
     3001 ggagtgacct tgtattaaat aactgcctgc tgctcagaga tgatctttat tctgtcattg
     3061 gggtatggga tagaagccct tgcttatttt taatctgatg aatctgtata gagcccatcg
     3121 ttgagttacc aagacaatac ctgctacagt attttgggga gcaaactaaa gaccagaact
     3181 taaattttca ctttagacat tggatgaata gtatgaagac agtttttcag ttgatttgga
     3241 taaaactatt ttagtgcatt gacaagtgta acttcaactt catatagaac catttttctt
     3301 tctgctttta ttgaaactga gtatttttct ttggctaatg tggatttttt atggggatat
     3361 ctgttaattt tcaggttttg aaagacatta acctcggaag ttgtttttaa gaattattct
     3421 cataattctt attctcataa tttctgtaat ccacctcaag cttcatagtt atttggcatt
     3481 gaaataacac ccagagcatg atagaaatgt tgttactctt cctctctcaa ggagaaagta
     3541 attttcctgc aatacttaat aattggcacc gttgctttct aaagactcca tggtgcattc
     3601 aagagtatcc aacttcaagg gaatctccgc atttcaatga aaggaggaag agtgtgctga
     3661 taaacctacc agcacctatt gagcaatgtc tattatagta attttgcata catttttatt
     3721 taagggaaaa aatataggta ttgtgaaata ttttgctaat cttatagaaa aggaaaaaat
     3781 cccgttattt aaagggaaaa gtaaatttaa cagttgcctt ttttcttaat gtcagggcag
     3841 atcttatttt acagtacagt gggggaaata gaaacatgtg aaaggcaaaa ggcaggctcc
     3901 taaattaatg tcagtgaagt tcagggtggg caaatgagtg tgtgtgaggt ataggaaatg
     3961 ctgatgactt ctttaatgct tgaagtccgt tcacaggtat ctagccctag aatgcctaga
     4021 acaggaagag gcagctggtg ttctgcaaaa cttggacagg ggcaaagttg ctgaaaaagt
     4081 tttggtttaa cccgaagata agtggaaaag agcttgtcca tgaacccagg ttctcactct
     4141 gtttacagaa gtgtgttgag tacagttggt gaaggaagag gtaacaaaaa atgctaaata
     4201 ttttatccat gaaaatgact tccagaaaag gaagaatatg aaccccagac cgaaggggaa
     4261 aagatagtta atagtattat ctaacctggt tggtatttgt aatgaatggt gattttaatt
     4321 agtcattagc cataatgatg tttatttaca gtataactcc tgaatgctac ttaaataaac
     4381 caggattcaa actgcaagcc agccaggccg ttcattattt aaaacgtttt aatcggggct
     4441 tccgggtaga aggtggagcg gcagggtgta attgggttga tgggtgggac ctgtcttgac
     4501 catcggagtt ttataatcga gggccaggag ggcccgggtt gctctcctgg ttatgtatgt
     4561 acttgtacat aaccacctaa agaatggtga aataaatgtt cttggaaatt ccta
//
