LOCUS       NM_001385469            5423 bp    mRNA    linear   PRI 15-DEC-2024
DEFINITION  Homo sapiens NBPF member 11 (NBPF11), transcript variant 6, mRNA.
ACCESSION   NM_001385469
VERSION     NM_001385469.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 5423)
  AUTHORS   Tsuritani,K., Irie,T., Yamashita,R., Sakakibara,Y., Wakaguri,H.,
            Kanai,A., Mizushima-Sugano,J., Sugano,S., Nakai,K. and Suzuki,Y.
  TITLE     Distinct class of putative 'non-conserved' promoters in humans:
            comparative studies of alternative promoters of human and mouse
            genes
  JOURNAL   Genome Res 17 (7), 1005-1014 (2007)
   PUBMED   17567985
REFERENCE   2  (bases 1 to 5423)
  AUTHORS   Vandepoele,K., Van Roy,N., Staes,K., Speleman,F. and van Roy,F.
  TITLE     A novel gene family NBPF: intricate structure generated by gene
            duplications during primate evolution
  JOURNAL   Mol Biol Evol 22 (11), 2265-2274 (2005)
   PUBMED   16079250
REFERENCE   3  (bases 1 to 5423)
  AUTHORS   Laureys,G., Speleman,F., Versteeg,R., van der Drift,P., Chan,A.,
            Leroy,J., Francke,U., Opdenakker,G. and Van Roy,N.
  TITLE     Constitutional translocation t(1;17)(p36.31-p36.13;q11.2-q12.1) in
            a neuroblastoma patient. Establishment of somatic cell hybrids and
            identification of PND/A12M2 on chromosome 1 and NF1/SCYA7 on
            chromosome 17 as breakpoint flanking single copy markers
  JOURNAL   Oncogene 10 (6), 1087-1093 (1995)
   PUBMED   7700633
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC239803.3.
            
            On Jul 20, 2020 this sequence version replaced NM_001385469.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR14038196.514247.1,
                                           SRR14372080.848892.1 [ECO:0000332]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            CDS uses downstream in-frame AUG :: upstream AUG and CDS extension
                                                is not conserved
            MANE Ensembl match               :: ENST00000682118.1/
                                                ENSP00000507808.1
            RefSeq Select criteria           :: based on manual assertion,
                                                longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-532               AC239803.3         25390-25921
            533-804             AC239803.3         33985-34256
            805-903             AC239803.3         39862-39960
            904-1045            AC239803.3         41858-41999
            1046-1255           AC239803.3         50633-50842
            1256-1358           AC239803.3         52670-52772
            1359-1573           AC239803.3         53604-53818
            1574-1646           AC239803.3         54870-54942
            1647-1858           AC239803.3         55405-55616
            1859-2068           AC239803.3         56961-57170
            2069-2171           AC239803.3         58949-59051
            2172-2386           AC239803.3         59885-60099
            2387-2459           AC239803.3         61136-61208
            2460-2665           AC239803.3         61673-61878
            2666-2717           AC239803.3         63183-63234
            2718-2881           AC239803.3         67130-67293
            2882-2933           AC239803.3         68336-68387
            2934-3106           AC239803.3         69017-69189
            3107-3158           AC239803.3         69909-69960
            3159-3331           AC239803.3         70557-70729
            3332-3383           AC239803.3         71439-71490
            3384-3552           AC239803.3         72143-72311
            3553-3661           AC239803.3         73026-73134
            3662-5423           AC239803.3         73759-75520
FEATURES             Location/Qualifiers
     source          1..5423
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="1"
                     /map="1q21.2"
     gene            1..5423
                     /gene="NBPF11"
                     /gene_synonym="NBPF24"
                     /note="NBPF member 11"
                     /db_xref="GeneID:200030"
                     /db_xref="HGNC:HGNC:31993"
                     /db_xref="MIM:614001"
     exon            1..532
                     /gene="NBPF11"
                     /gene_synonym="NBPF24"
                     /inference="alignment:Splign:2.1.0"
     exon            533..804
                     /gene="NBPF11"
                     /gene_synonym="NBPF24"
                     /inference="alignment:Splign:2.1.0"
     exon            805..903
                     /gene="NBPF11"
                     /gene_synonym="NBPF24"
                     /inference="alignment:Splign:2.1.0"
     exon            904..1045
                     /gene="NBPF11"
                     /gene_synonym="NBPF24"
                     /inference="alignment:Splign:2.1.0"
     exon            1046..1255
                     /gene="NBPF11"
                     /gene_synonym="NBPF24"
                     /inference="alignment:Splign:2.1.0"
     CDS             1081..3678
                     /gene="NBPF11"
                     /gene_synonym="NBPF24"
                     /note="isoform b is encoded by transcript variant 6;
                     neuroblastoma breakpoint family, member 24; neuroblastoma
                     breakpoint family member 11; NBPF family member NBPF11"
                     /codon_start=1
                     /product="NBPF family member NBPF11 isoform b"
                     /protein_id="NP_001372398.2"
                     /db_xref="CCDS:CCDS41381.2"
                     /db_xref="GeneID:200030"
                     /db_xref="HGNC:HGNC:31993"
                     /db_xref="MIM:614001"
                     /translation="MVVSAGPWSSEKAEMNILEINEKLRPQLAENKQQFRNLKERCFL
                     TQLAGFLANRQKKYKYEECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQ
                     ERELTQLREKLREGRDASRSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQ
                     KLSPENDEDEDEDVQVEEDEKVLESSAPREVQKAEESKVPEDSLEECAITCSNSHGPC
                     DSIQPHKNIKITFEEDKVNSSLVVDRESSHDGCQDALNILPVPGPTSSATNVSMVVSA
                     GPLSSEKAEMNILEINEKLCPQLAEKKQQFRSLKEKCFVTQVACFLAKQQNKYKYEEC
                     KDLIKSMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDASR
                     SLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVA
                     EKVQKSSSPREMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVD
                     STLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYS
                     TLSIPPERLASYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELL
                     DEKEPEVLQDSLDRCYSTPSVYLGLTDSCQPYRSAFYVLEQQRIGLAVDMDEIEKYQE
                     VEEDQDPSCPRLSRELLAEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYRSAVYSLEE
                     QYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDVIQLLPVVLNS
                     LTPASPTEVPFMHWRKNMLAFLLTWEKLKRRGRGRKEGEEDQRRKEEGEEKKGKKIKT
                     HHAPGSAAC"
     exon            1256..1358
                     /gene="NBPF11"
                     /gene_synonym="NBPF24"
                     /inference="alignment:Splign:2.1.0"
     exon            1359..1573
                     /gene="NBPF11"
                     /gene_synonym="NBPF24"
                     /inference="alignment:Splign:2.1.0"
     exon            1574..1646
                     /gene="NBPF11"
                     /gene_synonym="NBPF24"
                     /inference="alignment:Splign:2.1.0"
     exon            1647..1858
                     /gene="NBPF11"
                     /gene_synonym="NBPF24"
                     /inference="alignment:Splign:2.1.0"
     exon            1859..2068
                     /gene="NBPF11"
                     /gene_synonym="NBPF24"
                     /inference="alignment:Splign:2.1.0"
     exon            2069..2171
                     /gene="NBPF11"
                     /gene_synonym="NBPF24"
                     /inference="alignment:Splign:2.1.0"
     exon            2172..2386
                     /gene="NBPF11"
                     /gene_synonym="NBPF24"
                     /inference="alignment:Splign:2.1.0"
     exon            2387..2459
                     /gene="NBPF11"
                     /gene_synonym="NBPF24"
                     /inference="alignment:Splign:2.1.0"
     exon            2460..2665
                     /gene="NBPF11"
                     /gene_synonym="NBPF24"
                     /inference="alignment:Splign:2.1.0"
     exon            2666..2717
                     /gene="NBPF11"
                     /gene_synonym="NBPF24"
                     /inference="alignment:Splign:2.1.0"
     exon            2718..2881
                     /gene="NBPF11"
                     /gene_synonym="NBPF24"
                     /inference="alignment:Splign:2.1.0"
     exon            2882..2933
                     /gene="NBPF11"
                     /gene_synonym="NBPF24"
                     /inference="alignment:Splign:2.1.0"
     exon            2934..3106
                     /gene="NBPF11"
                     /gene_synonym="NBPF24"
                     /inference="alignment:Splign:2.1.0"
     exon            3107..3158
                     /gene="NBPF11"
                     /gene_synonym="NBPF24"
                     /inference="alignment:Splign:2.1.0"
     exon            3159..3331
                     /gene="NBPF11"
                     /gene_synonym="NBPF24"
                     /inference="alignment:Splign:2.1.0"
     exon            3332..3383
                     /gene="NBPF11"
                     /gene_synonym="NBPF24"
                     /inference="alignment:Splign:2.1.0"
     exon            3384..3552
                     /gene="NBPF11"
                     /gene_synonym="NBPF24"
                     /inference="alignment:Splign:2.1.0"
     exon            3553..3661
                     /gene="NBPF11"
                     /gene_synonym="NBPF24"
                     /inference="alignment:Splign:2.1.0"
     exon            3662..5423
                     /gene="NBPF11"
                     /gene_synonym="NBPF24"
                     /inference="alignment:Splign:2.1.0"
     regulatory      5403..5408
                     /regulatory_class="polyA_signal_sequence"
                     /gene="NBPF11"
                     /gene_synonym="NBPF24"
                     /note="hexamer: ATTAAA"
     polyA_site      5423
                     /gene="NBPF11"
                     /gene_synonym="NBPF24"
                     /note="major polyA site"
ORIGIN      
        1 gcagtcctaa acgcggggta gctccgggct tccgaggggg tgtgtctccc gcctctttaa
       61 cctggcaggg gcggttcaag tggccgggga aatcagcgaa ttgcagggtc aagggctggt
      121 gctttgaaag agaggcggag gggagagagg gattttcccg tccccgctgc gctctgtcct
      181 ccattactcc ttttctcggc ccgcggcccg aacccgctgt gcggtagagg cagccgggtc
      241 cctttaaggc ccagctgcgc ctgtgccttg ggctctcctg acacggccca tccggaccct
      301 gaggagccag cgggccgcaa gcaagttgct gggcggcggt ggagatagcg gcggtgctgg
      361 gaggggtagg tgagggtcgc gaggctgcct gagcttctga gtgagcctgg tgattttggg
      421 aacgcgggac gggcgacctg cggcgccagg agcggggccg aggtacggcg gcacggctgc
      481 agcctggatg ggaagttcaa gtttactgcg aagtccaccc agcgttccgg aggcattctg
      541 aaggcaaatc ctgtttagac ccaggcaaag gttcctggtg acccaggctc tcatgagcag
      601 attgtccctt atcattctcc tgaggatgtc tggagcttca gtgctgtgtg ctcttggcct
      661 ccacactggg ggtgccacca actcccactg tccagggctt ctggtggact ctccgaggca
      721 ccgatgtaga aacttaccca ttcagtgcac caagagcagc ttcacatggt gtgggccgac
      781 atgaagagct gccagatcca acagaaatgt gattgataac agtaaagcca cactcctcaa
      841 gtgcctgaaa tacccctcat tgtcttcttc aggtggcaag ggctctggaa cagccacata
      901 aagcccttga agataaggat ggtcaaacaa aataatatca tacctggaga aactcagatc
      961 ttgctaagat ttactggttg ggaatccaaa gttaatgcca agaagcagct gccagttggg
     1021 atcaaatgtg agcctatgga tcaagtccct gactccacct cttctgccac aaacgtcagc
     1081 atggtggtat cagccggccc ttggtccagc gagaaggcag agatgaacat tctagaaatc
     1141 aacgagaaat tgcgccccca gttggcagag aacaaacagc agttcagaaa cctcaaagag
     1201 agatgttttc taactcaact ggccggcttc ctggccaacc gacagaagaa atacaagtat
     1261 gaagagtgta aagacctcat aaaatttatg ctgaggaatg agcgacagtt caaggaggag
     1321 aagcttgcag agcagctcaa gcaagctgag gagctcaggc aatataaagt cctggttcac
     1381 tctcaggaac gagagctgac ccagttaagg gagaagttac gggaagggag agatgcctcc
     1441 cgctcattga atgagcatct ccaggccctc ctcactccgg atgagccgga caagtcccag
     1501 gggcaggacc tccaagaaca gctggctgag gggtgtagac tggcacagca ccttgtccaa
     1561 aagctcagcc cagaaaatga cgaagatgag gatgaagatg ttcaagttga ggaggatgag
     1621 aaagtactgg aatcatctgc ccccagggag gtgcagaagg ctgaagagag caaagtccct
     1681 gaggactcac tggaggaatg tgccatcact tgttcaaata gccacggccc ttgtgactcc
     1741 atccagcctc acaagaacat caaaatcaca tttgaggaag acaaagtcaa ctcatctctg
     1801 gttgtagaca gagaatcctc tcatgatgga tgtcaggatg ctctaaacat tctcccagtc
     1861 cctggcccca cctcttctgc cacaaacgtc agcatggtgg tatcagccgg ccctttgtcc
     1921 agcgagaagg cagagatgaa cattctagaa atcaatgaga aattgtgccc ccagctggca
     1981 gagaagaaac agcagttcag aagcctcaaa gagaaatgtt ttgtaactca agtggcctgc
     2041 ttcctggcca agcagcagaa caaatacaaa tatgaagagt gcaaagacct cataaaatct
     2101 atgctgagga atgagcgaca gttcaaggag gagaagcttg cagagcagct gaagcaagct
     2161 gaggagctca ggcaatataa agtcctggtt cactctcagg aacgagagct gacccagtta
     2221 agggagaagt tacgggaagg gagagatgcc tcccgctcat tgaatgagca tctccaggcc
     2281 ctcctcactc cggatgagcc ggacaagtcc caggggcagg acctccaaga acagctggct
     2341 gaggggtgta gactggcaca gcaccttgtc caaaagctca gcccagaaaa tgataacgat
     2401 gacgatgaag atgttcaagt tgaggtggct gagaaagtgc agaaatcgtc ttcccccagg
     2461 gagatgcaga aggctgaaga aaaggaagtc cctgaggact cactggagga gtgtgccatc
     2521 acttgttcaa atagccatgg cccttatgac tccaaccagc cacatagaaa aaccaaaatc
     2581 acatttgagg aagacaaagt cgactcaact ctcattggct catcctctca tgttgaatgg
     2641 gaggatgctg tacacattat cccagaaaat gaaagtgatg atgaggaaga ggaagaaaaa
     2701 gggccagtgt ctcccaggaa tctgcaggag tctgaagagg aggaagtccc ccaggagtcc
     2761 tgggatgaag gttattcgac tctctcaatt cctcctgaaa ggttggcctc gtaccagtct
     2821 tacagcagca catttcactc attagaggaa cagcaagtct gcatggctgt tgacataggc
     2881 agacatcggt gggatcaagt gaaaaaggag gaccaagagg caacaggtcc caggctcagc
     2941 agggagctgc tggatgagaa agagcctgaa gtcttgcagg actcactgga tagatgttat
     3001 tcaactcctt cagtttatct tggactgact gactcatgcc agccctacag aagtgccttt
     3061 tacgtattgg agcaacagcg tattggcttg gctgttgaca tggatgaaat tgaaaagtac
     3121 caagaagtgg aagaagacca agacccatca tgccccaggc tcagcaggga gctgctggct
     3181 gagaaagagc ctgaagtctt gcaggactca ctggatagat gttattcgac tccttcaggt
     3241 tatcttgaac tgcctgactt aggccagccc tacagaagtg ctgtttactc attggaggaa
     3301 cagtaccttg gcttggctct tgacgtggac agaattaaaa aggaccaaga agaggaagaa
     3361 gaccaaggcc caccgtgccc caggctcagc agggagctgc tggaggtagt agagcctgaa
     3421 gtcttgcagg actcactgga tgttattcaa ctccttccag ttgtcttgaa cagcctgact
     3481 cctgccagcc ctacggaagt tccttttatg cattggagga aaaacatgtt ggcttttctc
     3541 ttgacgtggg agaaattgaa aagaagggga aggggaagaa aagaagggga agaagatcaa
     3601 agaagaaaag aagaagggga agaaaagaag gggaagaaga tcaaaaccca ccatgcccca
     3661 ggctcagcag cgtgctgatg gaagtggaag tgcctgaagt cttacaggac tcactggata
     3721 gatattattc gactccatca atgtactttg aactacctga ctcattccag cactacagaa
     3781 gtgtgtttta ctcatttgag gaacagcaca tcagctttgc ccttgacatg gacaataggt
     3841 tttttacttt gacggtgaga agtctccacc tggtcttcca gatgggagtc atattcccac
     3901 aataagcagc ccttactaag ccgagaggtg tcattcctgc aggcaggacc tataggcacc
     3961 tgaagatttg aatgaaacta tagttccatt tggaagccca gacataggat gggtcagtgg
     4021 gcatggctct attcctattc tcagagcatg ccagtggcaa cctgtgctca gtctgaagac
     4081 aatggaccca cgttaggtgt gacacgttca cataactgtg cagcacatgc cgggagtgat
     4141 cagtcggaca ttttaatttg aaccacgtat ctctgggtag ctacaaaatt cctcagggat
     4201 ttcattttgc aggcatgtct ctgagcttct atacctgctc aaggtcagtg tcatctttgt
     4261 gtttagctca tccaaaggtg ttaccctggt ttcaatgaac ctaacctcat tctttgtgtc
     4321 ttcagtgttg gcttgtttta gctgatccat ctgtaacaca ggagggatcc ttggctgagg
     4381 attgtatttc agaaccacca actgctcttg acaattgtta acccgctagg ctcctttggt
     4441 tagagaagcc acagtccttc agcctccaat tggtgtcagt acttaggaag accacagcta
     4501 gatggacaaa cagcattggg aggccttagc cctgctcctc tcaattccat cctgtagaga
     4561 acaggagtca ggagccgctg gcaggagaca gcatgtcacc caggactctg ccggtgcaga
     4621 atatgagcaa tgccatgttc ttgcagaaaa cgcttagcct gagtttcata ggaggtaatc
     4681 accagacaac tgcagaatgt agaacactga gcaggacaac tgacctgtct ccttcacata
     4741 gtccatatca ccacaaatca cacaacaaaa aggagaagag atattttggg ttgaaaaaaa
     4801 gtaaaaagat aatgtagctg catttcttta gttattttga accccaaata tttcctcatc
     4861 tttttgttgt tgtcatggat ggtggtgaca tggacttgtt tatagaggac aggtcagctg
     4921 tctggctcaa tgatctacat tctgaagttg tctgaaaatg tcttcataat taaattcagc
     4981 ctaaactttt tgacgggaac actgcagaga caatgctgtg agtttccaac ctcagcccat
     5041 ctgcgggcag agaaggtcta gtttgtccaa caccattatg atatcaggac tggttacttg
     5101 gttaaggagg ggtctaggag atctgtccct tttagagaca ccttacttat aatgaagtac
     5161 ttgggaaagt ggttttcaag agtataaata tcctgtattc taatgatcat cctctaaaca
     5221 ttttatcatt tattaatcct ccctgcctgt gtctattatt atattcatat ctctacgctg
     5281 caaattttgg gtctcaattt ttactgtgcc tttgttttta ctagtgtctg ctgttgcaaa
     5341 aagaagaaaa cattctttgc ctgagtttta atttttgtcc aaagttaatt ttaatctata
     5401 caattaaaac cttttgccta tca
//
