LOCUS       NM_001385012           11200 bp    mRNA    linear   PRI 01-JUN-2024
DEFINITION  Homo sapiens neurobeachin (NBEA), transcript variant 4, mRNA.
ACCESSION   NM_001385012 XM_005266347
VERSION     NM_001385012.1
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 11200)
  AUTHORS   Miura,S., Shimojo,T., Morikawa,T., Kamada,T., Uchiyama,Y.,
            Kurata,S., Fujioka,R. and Shibata,H.
  TITLE     Familial paroxysmal kinesigenic dyskinesia with a novel missense
            variant (Arg2866Trp) in NBEA
  JOURNAL   J Hum Genet 66 (8), 805-811 (2021)
   PUBMED   33692494
  REMARK    GeneRIF: Familial paroxysmal kinesigenic dyskinesia with a novel
            missense variant (Arg2866Trp) in NBEA.
REFERENCE   2  (bases 1 to 11200)
  AUTHORS   Lipunova,N., Wesselius,A., Cheng,K.K., van Schooten,F.J.,
            Bryan,R.T., Cazier,J.B., Galesloot,T.E., Kiemeney,L.A.L.M. and
            Zeegers,M.P.
  TITLE     Genome-wide Association Study for Tumour Stage, Grade, Size, and
            Age at Diagnosis of Non-muscle-invasive Bladder Cancer
  JOURNAL   Eur Urol Oncol 2 (4), 381-389 (2019)
   PUBMED   31277774
  REMARK    GeneRIF: Our study suggests that rs180940944 (NBEA) is associated
            with an increased Non-muscle-invasive Bladder Cancer tumour size at
            the time of diagnosis
REFERENCE   3  (bases 1 to 11200)
  AUTHORS   Mulhern,M.S., Stumpel,C., Stong,N., Brunner,H.G., Bier,L.,
            Lippa,N., Riviello,J., Rouhl,R.P.W., Kempers,M., Pfundt,R.,
            Stegmann,A.P.A., Kukolich,M.K., Telegrafi,A., Lehman,A.,
            Lopez-Rangel,E., Houcinat,N., Barth,M., den Hollander,N.,
            Hoffer,M.J.V., Weckhuysen,S., Roovers,J., Djemie,T., Barca,D.,
            Ceulemans,B., Craiu,D., Lemke,J.R., Korff,C., Mefford,H.C.,
            Meyers,C.T., Siegler,Z., Hiatt,S.M., Cooper,G.M., Bebin,E.M.,
            Snijders Blok,L., Veenstra-Knol,H.E., Baugh,E.H., Brilstra,E.H.,
            Volker-Touw,C.M.L., van Binsbergen,E., Revah-Politi,A., Pereira,E.,
            McBrian,D., Pacault,M., Isidor,B., Le Caignec,C.,
            Gilbert-Dussardier,B., Bilan,F., Heinzen,E.L., Goldstein,D.B.,
            Stevens,S.J.C. and Sands,T.T.
  CONSRTM   CAUSES study; EuroEPINOMICS-RES-MAE working group
  TITLE     NBEA: Developmental disease gene with early generalized epilepsy
            phenotypes
  JOURNAL   Ann Neurol 84 (5), 788-795 (2018)
   PUBMED   30269351
  REMARK    GeneRIF: We identified 24 de novo NBEA variants in patients with
            neurodevelopmental disease, establishing NBEA as an
            neurodevelopmental disease gene
REFERENCE   4  (bases 1 to 11200)
  AUTHORS   Jacobsen,K.K., Nievergelt,C.M., Zayats,T., Greenwood,T.A.,
            Anttila,V., Akiskal,H.S., Haavik,J., Bernt Fasmer,O., Kelsoe,J.R.,
            Johansson,S. and Oedegaard,K.J.
  CONSRTM   BiGS Consortium; IHG Consortium
  TITLE     Genome wide association study identifies variants in NBEA
            associated with migraine in bipolar disorder
  JOURNAL   J Affect Disord 172, 453-461 (2015)
   PUBMED   25451450
  REMARK    GeneRIF: NBEA encodes neurobeachin: we found no evidence of
            association in data from the GWAS migraine meta-analysis consortium
            (n=118,710 participants) suggesting that the association might be
            specific to migraine co-morbid with bipolar disorder.
REFERENCE   5  (bases 1 to 11200)
  AUTHORS   Anttila,V., Winsvold,B.S., Gormley,P., Kurth,T., Bettella,F.,
            McMahon,G., Kallela,M., Malik,R., de Vries,B., Terwindt,G.,
            Medland,S.E., Todt,U., McArdle,W.L., Quaye,L., Koiranen,M.,
            Ikram,M.A., Lehtimaki,T., Stam,A.H., Ligthart,L., Wedenoja,J.,
            Dunham,I., Neale,B.M., Palta,P., Hamalainen,E., Schurks,M.,
            Rose,L.M., Buring,J.E., Ridker,P.M., Steinberg,S., Stefansson,H.,
            Jakobsson,F., Lawlor,D.A., Evans,D.M., Ring,S.M., Farkkila,M.,
            Artto,V., Kaunisto,M.A., Freilinger,T., Schoenen,J., Frants,R.R.,
            Pelzer,N., Weller,C.M., Zielman,R., Heath,A.C., Madden,P.A.F.,
            Montgomery,G.W., Martin,N.G., Borck,G., Gobel,H., Heinze,A.,
            Heinze-Kuhn,K., Williams,F.M.K., Hartikainen,A.L., Pouta,A., van
            den Ende,J., Uitterlinden,A.G., Hofman,A., Amin,N., Hottenga,J.J.,
            Vink,J.M., Heikkila,K., Alexander,M., Muller-Myhsok,B.,
            Schreiber,S., Meitinger,T., Wichmann,H.E., Aromaa,A.,
            Eriksson,J.G., Traynor,B., Trabzuni,D., Rossin,E., Lage,K.,
            Jacobs,S.B.R., Gibbs,J.R., Birney,E., Kaprio,J., Penninx,B.W.,
            Boomsma,D.I., van Duijn,C., Raitakari,O., Jarvelin,M.R.,
            Zwart,J.A., Cherkas,L., Strachan,D.P., Kubisch,C., Ferrari,M.D.,
            van den Maagdenberg,A.M.J.M., Dichgans,M., Wessman,M., Smith,G.D.,
            Stefansson,K., Daly,M.J., Nyholt,D.R., Chasman,D. and Palotie,A.
  CONSRTM   North American Brain Expression Consortium; UK Brain Expression
            Consortium
  TITLE     Genome-wide meta-analysis identifies new susceptibility loci for
            migraine
  JOURNAL   Nat Genet 45 (8), 912-917 (2013)
   PUBMED   23793025
REFERENCE   6  (bases 1 to 11200)
  AUTHORS   Castermans,D., Wilquet,V., Parthoens,E., Huysmans,C., Steyaert,J.,
            Swinnen,L., Fryns,J.P., Van de Ven,W. and Devriendt,K.
  TITLE     The neurobeachin gene is disrupted by a translocation in a patient
            with idiopathic autism
  JOURNAL   J Med Genet 40 (5), 352-356 (2003)
   PUBMED   12746398
  REMARK    GeneRIF: neurobeachin encoding gene is disrupted in a patient with
            a de novo translocation t(5;13) (q12.1;q13.2), idiopathic autism,
            and no family history of autism
REFERENCE   7  (bases 1 to 11200)
  AUTHORS   Jogl,G., Shen,Y., Gebauer,D., Li,J., Wiegmann,K., Kashkar,H.,
            Kronke,M. and Tong,L.
  TITLE     Crystal structure of the BEACH domain reveals an unusual fold and
            extensive association with a novel PH domain
  JOURNAL   EMBO J 21 (18), 4785-4795 (2002)
   PUBMED   12234919
  REMARK    GeneRIF: Structural analysis and biochemical studies show that the
            PH and BEACH domains have strong interactions, suggesting they may
            function as a single unit.
REFERENCE   8  (bases 1 to 11200)
  AUTHORS   Dyomin,V.G., Chaganti,S.R., Dyomina,K., Palanisamy,N., Murty,V.V.,
            Dalla-Favera,R. and Chaganti,R.S.
  TITLE     BCL8 is a novel, evolutionarily conserved human gene family
            encoding proteins with presumptive protein kinase A anchoring
            function
  JOURNAL   Genomics 80 (2), 158-165 (2002)
   PUBMED   12160729
REFERENCE   9  (bases 1 to 11200)
  AUTHORS   Wang,X., Herberg,F.W., Laue,M.M., Wullner,C., Hu,B.,
            Petrasch-Parwez,E. and Kilimann,M.W.
  TITLE     Neurobeachin: A protein kinase A-anchoring, beige/Chediak-higashi
            protein homolog implicated in neuronal membrane traffic
  JOURNAL   J Neurosci 20 (23), 8551-8565 (2000)
   PUBMED   11102458
REFERENCE   10 (bases 1 to 11200)
  AUTHORS   Gilbert,D.J., Engel,H., Wang,X., Grzeschik,K.H., Copeland,N.G.,
            Jenkins,N.A. and Kilimann,M.W.
  TITLE     The neurobeachin gene (Nbea) identifies a new region of homology
            between mouse central chromosome 3 and human chromosome 13q13
  JOURNAL   Mamm Genome 10 (10), 1030-1031 (1999)
   PUBMED   10501977
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from AL138690.19, AL161902.12,
            AL356430.19, AL357083.19, AL161718.14, AL390071.9 and AL139083.15.
            This sequence is a reference standard in the RefSeqGene project.
            
            On Jul 8, 2020 this sequence version replaced XM_005266347.4.
            
            Summary: This gene encodes a member of a large, diverse group of
            A-kinase anchor proteins that target the activity of protein kinase
            A to specific subcellular sites by binding to its type II
            regulatory subunits. Brain-specific expression and coat
            protein-like membrane recruitment of a highly similar protein in
            mouse suggest an involvement in neuronal post-Golgi membrane
            traffic. Mutations in this gene may be associated with a form of
            autism. This gene and its expression are frequently disrupted in
            patients with multiple myeloma. Alternative splicing results in
            multiple transcript variants encoding distinct isoforms. Additional
            transcript variants may exist, but their full-length nature has not
            been determined.[provided by RefSeq, Feb 2011].
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMEA1968540,
                              SAMEA1968968 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            inferred exon combination :: based on alignments, homology
            MANE Ensembl match        :: ENST00000379939.7/ ENSP00000369271.2
            RefSeq Select criteria    :: based on manual assertion,
                                         conservation, longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-845               AL138690.19        156912-157756
            846-1077            AL161902.12        69081-69312
            1078-1178           AL161902.12        73095-73195
            1179-1274           AL161902.12        73454-73549
            1275-1396           AL161902.12        76711-76832
            1397-1523           AL161902.12        78417-78543
            1524-1643           AL161902.12        84158-84277
            1644-1790           AL161902.12        86865-87011
            1791-1988           AL161902.12        98056-98253
            1989-2122           AL161902.12        98867-99000
            2123-2231           AL356430.19        21907-22015
            2232-2384           AL356430.19        32900-33052
            2385-2553           AL356430.19        34420-34588
            2554-2633           AL356430.19        41024-41103
            2634-2696           AL356430.19        41838-41900
            2697-2794           AL356430.19        41987-42084
            2795-2887           AL356430.19        47092-47184
            2888-2996           AL356430.19        65879-65987
            2997-3078           AL356430.19        79384-79465
            3079-3202           AL356430.19        79693-79816
            3203-3395           AL356430.19        80688-80880
            3396-4412           AL356430.19        82626-83642
            4413-4630           AL356430.19        85360-85577
            4631-4784           AL356430.19        87966-88119
            4785-4793           AL356430.19        92597-92605
            4794-4974           AL356430.19        94882-95062
            4975-5105           AL356430.19        97074-97204
            5106-5213           AL356430.19        100606-100713
            5214-5382           AL356430.19        105970-106138
            5383-5478           AL356430.19        107586-107681
            5479-5917           AL356430.19        119474-119912
            5918-6072           AL356430.19        132310-132464
            6073-6199           AL356430.19        134663-134789
            6200-6327           AL356430.19        156102-156229
            6328-6389           AL357083.19        45114-45175
            6390-6454           AL357083.19        64253-64317
            6455-6563           AL357083.19        103833-103941
            6564-6730           AL357083.19        106882-107048
            6731-6855           AL161718.14        52938-53062
            6856-6999           AL390071.9         14325-14468
            7000-7136           AL390071.9         34633-34769
            7137-7254           AL390071.9         112710-112827
            7255-7357           AL390071.9         113163-113265
            7358-7473           AL390071.9         117220-117335
            7474-7586           AL390071.9         129138-129250
            7587-7727           AL390071.9         146131-146271
            7728-7847           AL390071.9         155561-155680
            7848-8000           AL390071.9         168659-168811
            8001-8168           AL139083.15        19322-19489
            8169-8231           AL139083.15        37110-37172
            8232-8321           AL139083.15        37500-37589
            8322-8514           AL139083.15        40896-41088
            8515-8586           AL139083.15        43046-43117
            8587-8742           AL139083.15        46096-46251
            8743-8913           AL139083.15        46820-46990
            8914-9015           AL139083.15        56326-56427
            9016-9212           AL139083.15        58615-58811
            9213-9364           AL139083.15        59609-59760
            9365-11200          AL139083.15        62142-63977
FEATURES             Location/Qualifiers
     source          1..11200
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="13"
                     /map="13q13.3"
     gene            1..11200
                     /gene="NBEA"
                     /gene_synonym="BCL8B; LYST2; NEDEGE"
                     /note="neurobeachin"
                     /db_xref="GeneID:26960"
                     /db_xref="HGNC:HGNC:7648"
                     /db_xref="MIM:604889"
     exon            1..845
                     /gene="NBEA"
                     /gene_synonym="BCL8B; LYST2; NEDEGE"
                     /inference="alignment:Splign:2.1.0"
     CDS             552..9455
                     /gene="NBEA"
                     /gene_synonym="BCL8B; LYST2; NEDEGE"
                     /note="isoform 4 is encoded by transcript variant 4;
                     lysosomal-trafficking regulator 2"
                     /codon_start=1
                     /product="neurobeachin isoform 4"
                     /protein_id="NP_001371941.1"
                     /db_xref="CCDS:CCDS91801.1"
                     /db_xref="GeneID:26960"
                     /db_xref="HGNC:HGNC:7648"
                     /db_xref="MIM:604889"
                     /translation="MASEKPGPGPGLEPQPVGLIAVGAAGGGGGGSGGGGTGGSGMGE
                     LRGASGSGSVMLPAGMINPSVPIRNIRMKFAVLIGLIQVGEVSNRDIVETVLNLLVGG
                     EFDLEMNFIIQDAESITCMTELLEHCDVTCQAEIWSMFTAILRKSVRNLQTSTEVGLI
                     EQVLLKMSAVDDMIADLLVDMLGVLASYSITVKELKLLFSMLRGESGIWPRHAVKLLS
                     VLNQMPQRHGPDTFFNFPGCSAAAIALPPIAKWPYQNGFTLNTWFRMDPLNNINVDKD
                     KPYLYCFRTSKGVGYSAHFVGNCLIVTSLKSKGKGFQHCVKYDFQPRKWYMISIVHIY
                     NRWRNSEIRCYVNGQLVSYGDMAWHVNTNDSYDKCFLGSSETADANRVFCGQLGAVYV
                     FSEALNPAQIFAIHQLGPGYKSTFKFKSESDIHLAEHHKQVLYDGKLASSIAFTYNAK
                     ATDAQLCLESSPKENASIFVHSPHALMLQDVKAIVTHSIHSAIHSIGGIQVLFPLFAQ
                     LDNRQLNDSQVETTVCATLLAFLVELLKSSVAMQEQMLGGKGFLVIGYLLEKSSRVHI
                     TRAVLEQFLSFAKYLDGLSHGAPLLKQLCDHILFNPAIWIHTPAKVQLSLYTYLSAEF
                     IGTATIYTTIRRVGTVLQLMHTLKYYYWVINPADSSGITPKGLDGPRPSQKEIISLRA
                     FMLLFLKQLILKDRGVKEDELQSILNYLLTMHEDENIHDVLQLLVALMSEHPASMIPA
                     FDQRNGIRVIYKLLASKSESIWVQALKVLGYFLKHLGHKRKVEIMHTHSLFTLLGERL
                     MLHTNTVTVTTYNTLYEILTEQVCTQVVHKPHPEPDSTVKIQNPMILKVVATLLKNST
                     PSAELMEVRRLFLSDMIKLFSNSRENRRCLLQCSVWQDWMFSLGYINPKNSEEQKITE
                     MVYNIFRILLYHAIKYEWGGWRVWVDTLSIAHSKVTYEAHKEYLAKMYEEYQRQEEEN
                     IKKGKKGNVSTISGLSSQTTGAKGGMEIREIEDLSQSQSPESETDYPVSTDTRDLLMS
                     TKVSDDILGNSDRPGSGVHVEVHDLLVDIKAEKVEATEVKLDDMDLSPETLVGGENGA
                     LVEVESLLDNVYSAAVEKLQNNVHGSVGIIKKNEEKDNGPLITLADEKEDLPNSSTSF
                     LFDKIPKQEEKLLPELSSNHIIPNIQDTQVHLGVSDDLGLLAHMTGSVDLTCTSSIIE
                     EKEFKIHTTSDGMSSISERDLASSTKGLEYAEMTATTLETESSSSKIVPNIDAGSIIS
                     DTERSDDGKESGKEIRKIQTTTTTQAVQGRSITQQDRDLRVDLGFRGMPMTEEQRRQF
                     SPGPRTTMFRIPEFKWSPMHQRLLTDLLFALETDVHVWRSHSTKSVMDFVNSNENIIF
                     VHNTIHLISQMVDNIIIACGGILPLLSAATSPTGSKTELENIEVTQGMSAETAVTFLS
                     RLMAMVDVLVFASSLNFSEIEAEKNMSSGGLMRQCLRLVCCVAVRNCLECRQRQRDRG
                     NKSSHGSSKPQEVPQSVTATAASKTPLENVPGNLSPIKDPDRLLQDVDINRLRAVVFR
                     DVDDSKQAQFLALAVVYFISVLMVSKYRDILEPQRETTRTGSQPGRNIRQEINSPTST
                     VVVIPSIPHPSLNHGFLAKLIPEQSFGHSFYKETPAAFPDTIKEKETPTPGEDIQVES
                     SIPHTDSGIGEEQVASILNGAELETSTGPDAMSELLSTLSSEVKKSQESLTENPSETL
                     KPATSISSISQTKGINVKEILKSLVAAPVEIAECGPEPIPYPDPALKRETQAILPMQF
                     HSFDRSVVVPVKKPPPGSLAVTTVGATTAGSGLPTGSTSNIFAATGATPKSMINTTGA
                     VDSGSSSSSSSSSFVNGATSKNLPAVQTVAPMPEDSAENMSITAKLERALEKVAPLLR
                     EIFVDFAPFLSRTLLGSHGQELLIEGLVCMKSSTSVVELVMLLCSQEWQNSIQKNAGL
                     AFIELINEGRLLCHAMKDHIVRVANEAEFILNRQRAEDVHKHAEFESQCAQYAADRRE
                     EEKMCDHLISAAKHRDHVTANQLKQKILNILTNKHGAWGAVSHSQLHDFWRLDYWEDD
                     LRRRRRFVRNAFGSTHAEALLKAAIEYGTEEDVVKSKKTFRSQAIVNQNAETELMLEG
                     DDDAVSLLQEKEIDNLAGPVVLSTPAQLIAPVVVAKGTLSITTTEIYFEVDEDDSAFK
                     KIDTKVLAYTEGLHGKWMFSEIRAVFSRRYLLQNTALEVFMANRTSVMFNFPDQATVK
                     KVVYSLPRVGVGTSYGLPQARRISLATPRQLYKSSNMTQRWQRREISNFEYLMFLNTI
                     AGRTYNDLNQYPVFPWVLTNYESEELDLTLPGNFRDLSKPIGALNPKRAVFYAERYET
                     WEDDQSPPYHYNTHYSTATSTLSWLVRIEPFTTFFLNANDGKFDHPDRTFSSVARSWR
                     TSQRDTSDVKELIPEFYYLPEMFVNSNGYNLGVREDEVVVNDVDLPPWAKKPEDFVRI
                     NRMALESEFVSCQLHQWIDLIFGYKQRGPEAVRALNVFHYLTYEGSVNLDSITDPVLR
                     EIPEAYFIRDPHTFLLTKDFIKAMEAQIQNFGQTPSQLLIEPHPPRSSAMHLCFLPQS
                     PLMFKDQMQQDVIMVLKFPSNSPVTHVAANTLPHLTIPAVVTVTCSRLFAVNRWHNTV
                     GLRGAPGYSLDQAHHLPIEMDPLIANNSGVNKRQITDLVDQSIQINAHCFVVTADNRY
                     ILICGFWDKSFRVYSTETGKLTQIVFGHWDVVTCLARSESYIGGDCYIVSGSRDATLL
                     LWYWSGRHHIIGDNPNSSDYPAPRAVLTGHDHEVVCVSVCAELGLVISGAKEGPCLVH
                     TITGDLLRALEGPENCLFPRLISVSSEGHCIIYYERGRFSNFSINGKLLAQMEINDST
                     RAILLSSDGQNLVTGGDNGVVEVWQACDFKQLYIYPGCDAGIRAMDLSHDQRTLITGM
                     ASGSIVAFNIDFNRWHYEHQNRY"
     exon            846..1077
                     /gene="NBEA"
                     /gene_synonym="BCL8B; LYST2; NEDEGE"
                     /inference="alignment:Splign:2.1.0"
     exon            1078..1178
                     /gene="NBEA"
                     /gene_synonym="BCL8B; LYST2; NEDEGE"
                     /inference="alignment:Splign:2.1.0"
     exon            1179..1274
                     /gene="NBEA"
                     /gene_synonym="BCL8B; LYST2; NEDEGE"
                     /inference="alignment:Splign:2.1.0"
     exon            1275..1396
                     /gene="NBEA"
                     /gene_synonym="BCL8B; LYST2; NEDEGE"
                     /inference="alignment:Splign:2.1.0"
     exon            1397..1523
                     /gene="NBEA"
                     /gene_synonym="BCL8B; LYST2; NEDEGE"
                     /inference="alignment:Splign:2.1.0"
     exon            1524..1643
                     /gene="NBEA"
                     /gene_synonym="BCL8B; LYST2; NEDEGE"
                     /inference="alignment:Splign:2.1.0"
     exon            1644..1790
                     /gene="NBEA"
                     /gene_synonym="BCL8B; LYST2; NEDEGE"
                     /inference="alignment:Splign:2.1.0"
     exon            1791..1988
                     /gene="NBEA"
                     /gene_synonym="BCL8B; LYST2; NEDEGE"
                     /inference="alignment:Splign:2.1.0"
     exon            1989..2122
                     /gene="NBEA"
                     /gene_synonym="BCL8B; LYST2; NEDEGE"
                     /inference="alignment:Splign:2.1.0"
     exon            2123..2231
                     /gene="NBEA"
                     /gene_synonym="BCL8B; LYST2; NEDEGE"
                     /inference="alignment:Splign:2.1.0"
     exon            2232..2384
                     /gene="NBEA"
                     /gene_synonym="BCL8B; LYST2; NEDEGE"
                     /inference="alignment:Splign:2.1.0"
     exon            2385..2553
                     /gene="NBEA"
                     /gene_synonym="BCL8B; LYST2; NEDEGE"
                     /inference="alignment:Splign:2.1.0"
     exon            2554..2633
                     /gene="NBEA"
                     /gene_synonym="BCL8B; LYST2; NEDEGE"
                     /inference="alignment:Splign:2.1.0"
     exon            2634..2696
                     /gene="NBEA"
                     /gene_synonym="BCL8B; LYST2; NEDEGE"
                     /inference="alignment:Splign:2.1.0"
     exon            2697..2794
                     /gene="NBEA"
                     /gene_synonym="BCL8B; LYST2; NEDEGE"
                     /inference="alignment:Splign:2.1.0"
     exon            2795..2887
                     /gene="NBEA"
                     /gene_synonym="BCL8B; LYST2; NEDEGE"
                     /inference="alignment:Splign:2.1.0"
     exon            2888..2996
                     /gene="NBEA"
                     /gene_synonym="BCL8B; LYST2; NEDEGE"
                     /inference="alignment:Splign:2.1.0"
     exon            2997..3078
                     /gene="NBEA"
                     /gene_synonym="BCL8B; LYST2; NEDEGE"
                     /inference="alignment:Splign:2.1.0"
     exon            3079..3202
                     /gene="NBEA"
                     /gene_synonym="BCL8B; LYST2; NEDEGE"
                     /inference="alignment:Splign:2.1.0"
     exon            3203..3395
                     /gene="NBEA"
                     /gene_synonym="BCL8B; LYST2; NEDEGE"
                     /inference="alignment:Splign:2.1.0"
     exon            3396..4412
                     /gene="NBEA"
                     /gene_synonym="BCL8B; LYST2; NEDEGE"
                     /inference="alignment:Splign:2.1.0"
     exon            4413..4630
                     /gene="NBEA"
                     /gene_synonym="BCL8B; LYST2; NEDEGE"
                     /inference="alignment:Splign:2.1.0"
     exon            4631..4784
                     /gene="NBEA"
                     /gene_synonym="BCL8B; LYST2; NEDEGE"
                     /inference="alignment:Splign:2.1.0"
     exon            4785..4793
                     /gene="NBEA"
                     /gene_synonym="BCL8B; LYST2; NEDEGE"
                     /inference="alignment:Splign:2.1.0"
     exon            4794..4974
                     /gene="NBEA"
                     /gene_synonym="BCL8B; LYST2; NEDEGE"
                     /inference="alignment:Splign:2.1.0"
     exon            4975..5105
                     /gene="NBEA"
                     /gene_synonym="BCL8B; LYST2; NEDEGE"
                     /inference="alignment:Splign:2.1.0"
     exon            5106..5213
                     /gene="NBEA"
                     /gene_synonym="BCL8B; LYST2; NEDEGE"
                     /inference="alignment:Splign:2.1.0"
     exon            5214..5382
                     /gene="NBEA"
                     /gene_synonym="BCL8B; LYST2; NEDEGE"
                     /inference="alignment:Splign:2.1.0"
     exon            5383..5478
                     /gene="NBEA"
                     /gene_synonym="BCL8B; LYST2; NEDEGE"
                     /inference="alignment:Splign:2.1.0"
     exon            5479..5917
                     /gene="NBEA"
                     /gene_synonym="BCL8B; LYST2; NEDEGE"
                     /inference="alignment:Splign:2.1.0"
     exon            5918..6072
                     /gene="NBEA"
                     /gene_synonym="BCL8B; LYST2; NEDEGE"
                     /inference="alignment:Splign:2.1.0"
     exon            6073..6199
                     /gene="NBEA"
                     /gene_synonym="BCL8B; LYST2; NEDEGE"
                     /inference="alignment:Splign:2.1.0"
     exon            6200..6327
                     /gene="NBEA"
                     /gene_synonym="BCL8B; LYST2; NEDEGE"
                     /inference="alignment:Splign:2.1.0"
     exon            6328..6389
                     /gene="NBEA"
                     /gene_synonym="BCL8B; LYST2; NEDEGE"
                     /inference="alignment:Splign:2.1.0"
     exon            6390..6454
                     /gene="NBEA"
                     /gene_synonym="BCL8B; LYST2; NEDEGE"
                     /inference="alignment:Splign:2.1.0"
     exon            6455..6563
                     /gene="NBEA"
                     /gene_synonym="BCL8B; LYST2; NEDEGE"
                     /inference="alignment:Splign:2.1.0"
     exon            6564..6730
                     /gene="NBEA"
                     /gene_synonym="BCL8B; LYST2; NEDEGE"
                     /inference="alignment:Splign:2.1.0"
     exon            6731..6855
                     /gene="NBEA"
                     /gene_synonym="BCL8B; LYST2; NEDEGE"
                     /inference="alignment:Splign:2.1.0"
     exon            6856..6999
                     /gene="NBEA"
                     /gene_synonym="BCL8B; LYST2; NEDEGE"
                     /inference="alignment:Splign:2.1.0"
     exon            7000..7136
                     /gene="NBEA"
                     /gene_synonym="BCL8B; LYST2; NEDEGE"
                     /inference="alignment:Splign:2.1.0"
     exon            7137..7254
                     /gene="NBEA"
                     /gene_synonym="BCL8B; LYST2; NEDEGE"
                     /inference="alignment:Splign:2.1.0"
     exon            7255..7357
                     /gene="NBEA"
                     /gene_synonym="BCL8B; LYST2; NEDEGE"
                     /inference="alignment:Splign:2.1.0"
     exon            7358..7473
                     /gene="NBEA"
                     /gene_synonym="BCL8B; LYST2; NEDEGE"
                     /inference="alignment:Splign:2.1.0"
     exon            7474..7586
                     /gene="NBEA"
                     /gene_synonym="BCL8B; LYST2; NEDEGE"
                     /inference="alignment:Splign:2.1.0"
     exon            7587..7727
                     /gene="NBEA"
                     /gene_synonym="BCL8B; LYST2; NEDEGE"
                     /inference="alignment:Splign:2.1.0"
     exon            7728..7847
                     /gene="NBEA"
                     /gene_synonym="BCL8B; LYST2; NEDEGE"
                     /inference="alignment:Splign:2.1.0"
     exon            7848..8000
                     /gene="NBEA"
                     /gene_synonym="BCL8B; LYST2; NEDEGE"
                     /inference="alignment:Splign:2.1.0"
     exon            8001..8168
                     /gene="NBEA"
                     /gene_synonym="BCL8B; LYST2; NEDEGE"
                     /inference="alignment:Splign:2.1.0"
     exon            8169..8231
                     /gene="NBEA"
                     /gene_synonym="BCL8B; LYST2; NEDEGE"
                     /inference="alignment:Splign:2.1.0"
     exon            8232..8321
                     /gene="NBEA"
                     /gene_synonym="BCL8B; LYST2; NEDEGE"
                     /inference="alignment:Splign:2.1.0"
     exon            8322..8514
                     /gene="NBEA"
                     /gene_synonym="BCL8B; LYST2; NEDEGE"
                     /inference="alignment:Splign:2.1.0"
     exon            8515..8586
                     /gene="NBEA"
                     /gene_synonym="BCL8B; LYST2; NEDEGE"
                     /inference="alignment:Splign:2.1.0"
     exon            8587..8742
                     /gene="NBEA"
                     /gene_synonym="BCL8B; LYST2; NEDEGE"
                     /inference="alignment:Splign:2.1.0"
     exon            8743..8913
                     /gene="NBEA"
                     /gene_synonym="BCL8B; LYST2; NEDEGE"
                     /inference="alignment:Splign:2.1.0"
     exon            8914..9015
                     /gene="NBEA"
                     /gene_synonym="BCL8B; LYST2; NEDEGE"
                     /inference="alignment:Splign:2.1.0"
     exon            9016..9212
                     /gene="NBEA"
                     /gene_synonym="BCL8B; LYST2; NEDEGE"
                     /inference="alignment:Splign:2.1.0"
     exon            9213..9364
                     /gene="NBEA"
                     /gene_synonym="BCL8B; LYST2; NEDEGE"
                     /inference="alignment:Splign:2.1.0"
     exon            9365..11200
                     /gene="NBEA"
                     /gene_synonym="BCL8B; LYST2; NEDEGE"
                     /inference="alignment:Splign:2.1.0"
     regulatory      11173..11178
                     /regulatory_class="polyA_signal_sequence"
                     /gene="NBEA"
                     /gene_synonym="BCL8B; LYST2; NEDEGE"
                     /note="hexamer: AAGAAA"
     regulatory      11179..11184
                     /regulatory_class="polyA_signal_sequence"
                     /gene="NBEA"
                     /gene_synonym="BCL8B; LYST2; NEDEGE"
                     /note="hexamer: AATAAA"
     polyA_site      11193
                     /gene="NBEA"
                     /gene_synonym="BCL8B; LYST2; NEDEGE"
     polyA_site      11200
                     /gene="NBEA"
                     /gene_synonym="BCL8B; LYST2; NEDEGE"
                     /note="major polyA site"
ORIGIN      
        1 gcagtggctg ctaccgcagg cagggggcgg caacatggcg gagtgagcgg cggcgtcggg
       61 gcttcacaac aacagtggtg gccgtagcag cggcggcagc agcgtcaata gcatcggcca
      121 cagcctgagc ttcagcaccg gccagcgtcg tggccagctg ctcgcgtcct cgggcttctc
      181 ggagcggctg cagcatctcc gcggggggcg ggccgggccg gacagaccgg gagagggaga
      241 gagcagaggc agcggcggcg gcagcggcag cggcagcggc acacctgctg ggcgggcaca
      301 gccgcttgcc cggcagcggt tagcggtacc gccaccgccg agaataagcc tgcggatccc
      361 ccgccgcctc cgcgggggag agcgccggag cgggccgggc tgaggcgcag gcggggagcg
      421 ggcccggcgc cgcggcgctg gtggatgctg gggctccgag gcgacggccg gggggcgggg
      481 gccgaggcag gtataacggt accggcggcg gcagcgccgc tgctcttccc ttctcctcag
      541 gaggggggcc aatggctagc gagaagccgg gcccgggccc ggggctcgag cctcagcccg
      601 tggggctcat tgccgtcggg gccgctggcg gaggcggcgg gggcagcggt ggtggcggca
      661 ccgggggcag cgggatgggg gagctaaggg gggcgtccgg ctccggctcg gtgatgctcc
      721 ccgcggggat gattaaccct tcggtgccga tccgcaacat ccggatgaaa ttcgcagtgt
      781 tgattggact catacaggtc ggagaggtca gcaacaggga catcgtggag acggtgctca
      841 acctgctggt tggtggagaa tttgacttgg agatgaactt tattatccag gatgctgaga
      901 gtataacatg tatgacagag cttttggagc actgtgatgt aacatgtcaa gcagaaatat
      961 ggagcatgtt tacagccatt ctacgaaaaa gtgttcggaa tttacagact agcacagaag
     1021 ttgggctaat tgaacaagta ttgctgaaaa tgagtgctgt agatgacatg atagcagatc
     1081 ttctagttga tatgttgggg gttcttgcca gctacagcat cactgtcaag gagttgaagc
     1141 ttttgttcag catgcttcga ggagaaagtg gaatctggcc aagacatgca gtaaaattat
     1201 tatcagttct taatcagatg ccacagagac acggtcctga tacttttttc aatttccctg
     1261 gttgtagcgc tgcggcaatt gccttgcctc ctattgcaaa gtggccttat cagaatggct
     1321 tcaccttaaa cacttggttt cgtatggatc cattaaataa tattaatgtt gataaggata
     1381 aaccttatct ttattgtttt cgtactagca aaggagttgg ttactctgct cattttgttg
     1441 gcaactgttt aatagtcaca tcattgaagt ccaaaggaaa aggttttcag cattgtgtga
     1501 aatatgattt tcaaccacgc aagtggtaca tgatcagcat tgtccacatt tacaatcgat
     1561 ggaggaacag tgaaattcgg tgttatgtta atggacaact ggtatcttat ggtgatatgg
     1621 cttggcatgt taacacaaat gatagctatg acaagtgctt tcttggatca tcagaaactg
     1681 ctgatgcaaa tagggtattc tgtggtcaac ttggtgccgt gtatgtgttc agtgaagcac
     1741 tcaacccagc acagatattt gcaattcatc agttaggacc tggatataag agtaccttca
     1801 agtttaaatc tgagagtgat attcatttgg cagaacatca taaacaggtg ttatatgatg
     1861 ggaaacttgc aagtagcatt gcctttacat ataatgctaa ggccactgat gctcagctct
     1921 gcctggaatc atcaccaaaa gagaatgcat caatttttgt gcattcccca catgctctaa
     1981 tgcttcagga tgtgaaagcg atagtaacac attcaattca tagtgcaatt cattcaattg
     2041 gagggattca agtgcttttt ccactttttg cccaattgga taataggcag ctcaatgaca
     2101 gtcaagtgga aacaactgtc tgtgctactc tgttggcatt cctggttgaa ctacttaaaa
     2161 gttcagtagc catgcaagaa cagatgctgg gtggaaaagg ctttttagtc attggctact
     2221 tacttgaaaa gtcatcaaga gttcatataa ctagagctgt cctggagcaa tttttatctt
     2281 ttgcaaaata ccttgatggt ttatctcatg gagcaccttt gctgaagcag ctttgtgatc
     2341 acattttatt taacccagcc atctggatac atacacctgc aaaggttcag ctttccctat
     2401 acacatattt gtctgctgaa tttattggaa ctgctaccat ctacaccacc atacgcagag
     2461 taggaacagt attacagcta atgcacacct taaaatatta ctactgggtt attaatcctg
     2521 ctgacagtag tggcattaca cctaaaggat tagatggtcc ccggccatca caaaaagaaa
     2581 ttatatcact gagggcattt atgctacttt ttctgaaaca gctgatacta aaggatcgag
     2641 gggtcaagga agatgaactt cagagtatat taaattacct acttacgatg catgaggatg
     2701 aaaatattca tgatgtgcta cagttactgg tggctttaat gtcggaacac ccagcctcaa
     2761 tgataccagc atttgatcaa agaaatggaa taagggtgat ctacaaatta ttggcttcta
     2821 aaagtgaaag tatttgggtt caagctttga aggttctggg atactttctg aagcatttag
     2881 gtcacaagag aaaagttgaa attatgcaca cccatagtct tttcactctt cttggagaaa
     2941 ggctgatgtt gcatacaaac actgtgactg tcaccacata caacacactt tatgagatct
     3001 tgacagaaca agtatgtact caggtcgtac acaaaccaca tccagagcca gattctacag
     3061 tgaaaattca gaatccaatg attcttaaag tggtggcaac tttgttaaaa aactctacac
     3121 caagtgcaga gctgatggaa gttcgtcgtt tatttttatc tgatatgata aaacttttca
     3181 gtaacagccg tgaaaataga agatgcttat tgcagtgttc agtgtggcag gattggatgt
     3241 tttctcttgg ctatatcaat cctaaaaatt ctgaggaaca gaagattacc gaaatggtct
     3301 acaatatctt ccggattctt ttgtatcatg caataaaata tgaatgggga ggctggagag
     3361 tctgggtgga taccctctca atagcccatt ccaaggtcac ttatgaagct cataaggaat
     3421 acctagccaa aatgtatgag gaatatcaaa gacaagagga ggaaaacatt aaaaagggaa
     3481 agaaagggaa tgtgagcacc atctctggtc tttcatcaca gacaacagga gcaaaaggtg
     3541 gaatggaaat tcgagagata gaagatcttt cacaaagcca gagcccagaa agtgagaccg
     3601 attaccctgt cagcacagat actcgagact tactcatgtc aacaaaagtg tcagatgata
     3661 ttcttggaaa ttcagataga ccaggaagtg gtgtacatgt ggaagtacat gatcttttag
     3721 tagatataaa agcagagaaa gtggaagcaa cagaagtaaa gctcgatgat atggatttat
     3781 caccggagac tttagtaggt ggagagaatg gtgcccttgt ggaggttgaa tctctgttgg
     3841 ataatgtata tagtgctgct gttgagaaac tccagaacaa tgtacatgga agtgttggta
     3901 tcattaaaaa aaatgaagaa aaggataatg gtccattgat aacattagca gatgagaaag
     3961 aagaccttcc caatagtagt acatcatttc tctttgataa aatacccaaa caggaggaaa
     4021 aactacttcc tgaactttct agcaatcaca ttattccaaa tattcaggac acacaagtac
     4081 atcttggtgt tagtgatgat cttggattgc ttgctcacat gaccggtagc gtagacttaa
     4141 cttgtacatc cagtataata gaagaaaaag aattcaaaat ccatacaact tcagatggaa
     4201 tgagcagtat ttctgaaaga gacttagcgt catcaactaa ggggctggag tatgctgaaa
     4261 tgactgctac aactctggaa actgagtctt ctagtagcaa aattgtacca aatattgatg
     4321 caggaagtat aatttcagat actgaaaggt ctgacgatgg caaagaatca ggaaaagaaa
     4381 tccgaaaaat ccaaacaact actacgacac aagctgtgca gggtcggtct atcacccaac
     4441 aagaccgaga tctccgagtt gatttaggat ttcgaggaat gccaatgact gaggaacagc
     4501 gacgccagtt tagcccaggt ccacggacta caatgtttcg tattcctgag tttaaatggt
     4561 ctccaatgca ccagcggctt ctcactgatt tactatttgc attagaaact gatgtacatg
     4621 tttggaggag ccattctaca aagtctgtaa tggattttgt caatagcaat gaaaatatta
     4681 tttttgtaca taacacaatt cacctcattt cccaaatggt agacaacatc atcattgctt
     4741 gtggaggaat tttacctttg ctctctgctg ctacatcacc aactggttct aagacggaat
     4801 tggaaaatat tgaagtgaca caaggcatgt cagctgagac agcagtaact ttcctcagcc
     4861 ggctgatggc tatggttgat gtacttgtgt ttgcaagctc tctaaatttt agtgagattg
     4921 aagctgagaa aaacatgtct tctggaggtt taatgcgaca gtgcctaaga ttagtttgtt
     4981 gtgttgctgt gagaaactgt ttagaatgtc ggcaaagaca gagagacagg ggaaataaat
     5041 cttcccatgg aagcagtaaa cctcaggaag ttcctcaaag tgtgactgct acagcagctt
     5101 cgaagactcc attggaaaat gttccaggta acctttctcc tattaaggat ccggatagac
     5161 ttcttcagga tgttgatatc aatcgccttc gtgctgttgt ctttcgggat gtggatgata
     5221 gcaaacaagc acagttctta gctctggctg ttgtttactt catttcggtt ctgatggttt
     5281 ccaagtatcg tgacatatta gaaccccaga gagagactac aagaactgga agccaaccag
     5341 gtagaaacat caggcaagaa ataaattcac caacaagtac agttgtggtc ataccatcta
     5401 tccctcatcc aagtttgaac catggattcc ttgccaagtt aattcctgag cagagctttg
     5461 gccactcatt ttacaaagaa acacctgctg catttccaga caccataaaa gaaaaagaaa
     5521 caccaactcc tggtgaagat attcaggtag aaagttcaat tccccataca gattcaggaa
     5581 ttggagagga gcaagtggct agcatcctga atggggcaga attagaaaca agtacaggcc
     5641 ctgatgccat gagtgaactc ttatccactt tgtcatccga agtgaagaaa tcacaagaga
     5701 gcttaactga aaatcctagt gaaacgttga agcctgcaac atccatatct agcattagtc
     5761 aaaccaaagg catcaatgtg aaggaaatac tgaaaagtct tgtggctgct ccagttgaaa
     5821 tagcagaatg tggccctgaa cctatcccat acccagatcc agcattgaag agagaaacac
     5881 aagctattct tcctatgcag tttcattcct ttgacaggag tgttgtggtg cctgtaaaga
     5941 aaccacctcc aggtagttta gctgtaacca ctgtgggagc cactactgct ggaagtgggc
     6001 tgccaacagg cagtacctct aatatatttg ctgctactgg agctacacca aaaagtatga
     6061 ttaatacaac aggtgccgtg gattcagggt cctcctcctc ttcctcctct tctagttttg
     6121 tgaatggtgc tactagcaaa aaccttccag ctgtacaaac tgttgctcca atgccagaag
     6181 attcagctga aaatatgagc atcactgcaa aacttgaaag agcgttagaa aaagttgctc
     6241 ctcttcttcg tgaaattttt gtagactttg ccccattcct atctcgtaca cttcttggca
     6301 gtcatggaca agagctattg atagaaggcc ttgtttgtat gaagtccagc acatctgtgg
     6361 ttgagcttgt tatgctgctt tgttctcagg aatggcaaaa ctctattcag aagaatgcag
     6421 gacttgcatt tattgagctc atcaatgaag gaagattact gtgccatgct atgaaggacc
     6481 atatagtccg tgttgcaaat gaagctgagt ttattttgaa cagacaaaga gccgaggatg
     6541 tacataaaca tgcagagttt gagtcacagt gtgcccaata tgctgctgat agaagagagg
     6601 aagaaaagat gtgtgaccat cttatcagtg ctgctaaaca tcgagatcat gtaacagcaa
     6661 atcagctgaa acagaagatt ctcaatattc tcacaaataa acatggtgct tggggagcag
     6721 tttctcatag ccaattgcat gatttctggc gtttggatta ctgggaagat gatcttcgtc
     6781 gaaggagacg atttgttcgc aatgcatttg gctccactca tgctgaagca ttgctgaaag
     6841 ctgcaataga atatggcacg gaagaagatg tagtaaagtc aaagaaaaca ttcagaagtc
     6901 aagcaatagt gaaccaaaat gcagagacag aacttatgct ggaaggagac gatgatgcag
     6961 tcagtctgct acaggagaaa gaaattgaca accttgcagg cccagtggtt ctcagcaccc
     7021 ctgcccagct catcgctccc gtggtggtgg ccaaggggac tctctccatc accacgacag
     7081 aaatctactt cgaggtagat gaggatgatt ctgccttcaa gaagatcgac acgaaagttc
     7141 ttgcatacac tgagggactt cacggaaaat ggatgttcag cgagatacga gctgtatttt
     7201 caagacgtta ccttctacaa aacactgctt tggaagtatt tatggcaaac cgaacctcag
     7261 ttatgtttaa tttccctgat caagcaacag taaaaaaagt tgtctatagc ttgcctcggg
     7321 ttggagtagg gaccagctat ggtctgccac aagccaggag gatatcattg gccactcctc
     7381 gacagcttta taaatcttcc aatatgactc agcgctggca aagaagggaa atttcaaact
     7441 tcgaatattt gatgttcctt aatactattg caggacggac atataatgat ctgaaccaat
     7501 atccagtgtt tccgtgggtg ttaaccaact atgaatcaga agagttggac ctgactcttc
     7561 caggaaactt cagggatcta tcaaagccaa ttggtgcttt gaaccccaag agagctgtgt
     7621 tttatgcaga gcgttatgag acatgggaag atgatcaaag cccaccctac cattataata
     7681 cccattattc aacagcaaca tctactttat cctggcttgt tcgaattgaa cctttcacaa
     7741 ccttcttcct caatgcaaat gatggaaaat ttgatcatcc agatcgaacc ttctcatccg
     7801 ttgcaaggtc ttggagaact agtcagagag atacttctga tgtaaaggaa ctaattccag
     7861 agttctacta cctaccagag atgtttgtca acagtaatgg atataatctt ggagtcagag
     7921 aagatgaagt agtggtaaat gatgttgatc ttcccccttg ggcaaaaaaa cctgaagact
     7981 ttgtgcggat caacaggatg gccctagaaa gtgaatttgt ttcttgccaa cttcatcagt
     8041 ggatcgacct tatatttggc tataagcagc gaggaccaga agcagttcgt gctctgaatg
     8101 tttttcacta cttgacttat gaaggctctg tgaacctgga tagtatcact gatcctgtgc
     8161 tcagggagat tccagaagct tatttcatta gagaccccca cactttcctt cttacaaagg
     8221 actttattaa ggccatggag gcacagatac agaactttgg acagacgcca tctcagttgc
     8281 ttattgagcc acatccgcct cggagctctg ccatgcacct gtgtttcctt ccacagagtc
     8341 cgctcatgtt taaagatcag atgcaacagg atgtgataat ggtgctgaag tttccttcaa
     8401 attctccagt aacccatgtg gcagccaaca ctctgcccca cttgaccatc cccgcagtgg
     8461 tgacagtgac ttgcagccga ctctttgcag tgaatagatg gcacaacaca gtaggcctca
     8521 gaggagctcc aggatactcc ttggatcaag cccaccatct tcccattgaa atggatccat
     8581 taatagccaa taattcaggt gtaaacaaac ggcagatcac agacctcgtt gaccagagta
     8641 tacaaatcaa tgcacattgt tttgtggtaa cagcagataa tcgctatatt cttatctgtg
     8701 gattctggga taagagcttc agagtttatt ctacagaaac agggaaattg actcagattg
     8761 tatttggcca ttgggatgtg gtcacttgct tggccaggtc cgagtcatac attggtgggg
     8821 actgctacat cgtgtccgga tctcgagatg ccaccctgct gctctggtac tggagtgggc
     8881 ggcaccatat cataggagac aaccctaaca gcagtgacta tccggcacca agagccgtcc
     8941 tcacaggcca tgaccatgaa gttgtctgtg tttctgtctg tgcagaactt gggcttgtta
     9001 tcagtggtgc taaagagggc ccttgccttg tccacaccat cactggagat ttgctgagag
     9061 cccttgaagg accagaaaac tgcttattcc cacgcttgat atctgtctcc agcgaaggcc
     9121 actgtatcat atactatgaa cgagggcgat tcagtaattt cagcattaat gggaaacttt
     9181 tggctcaaat ggagatcaat gattcaacac gggccattct cctgagcagt gacggccaga
     9241 acctggtcac cggaggggac aatggggtag tagaggtctg gcaggcctgt gacttcaagc
     9301 aactgtacat ttaccctgga tgtgatgctg gcattagagc aatggacttg tcccatgacc
     9361 agaggactct gatcactggc atggcttctg gtagcattgt agcttttaat atagatttta
     9421 atcggtggca ttatgagcat cagaacagat actgaagata aaggaagaac caaaagccaa
     9481 gttaaagctg agagcacaag tgctgcatgg aaaggcaata tctctggtgg aaaaaactcg
     9541 tctacatcga cctccgtttg tacattccat cacacccagc aatagctgta cattgtagtc
     9601 agcaaccatt ttactttgtg tgttttttca cgactgaaca ccagctgcta tcaagcaagc
     9661 ttatatcatg taaattatat gaattaggag atgttttggt aattatttca tatattgttg
     9721 tttattgaga aaaggttgta ggatgtgtca caagagactt ttgacaattc tgaggaacct
     9781 tgtgtccagt tgttacaaag tttaagcttt gaacctaacc tgcatcccat ttccagcctc
     9841 ttttcaagct gagaaaaaaa aaaaaaaaca cgtttgatac tttgtacatc agatgcatct
     9901 tatttaaaag ggatactttt gtaaaagtaa aaccttgtat aaagaacaaa atgtttctta
     9961 attttattgt ggagttacaa cttgcatgtt ccttactcct gttggcttga tggaacaggt
    10021 gcattcacac tatgaaacag aaagatctgt ccaaggacac agcttgtatg aaagggttga
    10081 atttgggctc catcagtaat ttttgacatt ttcaccaaaa tatagtttgc actttttaat
    10141 ctaaagtcat cccttctgag tgaaatttgc tcataaagca tttggatact aagccattat
    10201 ttgccatttt gggtacttta tacaaagaaa attcagccct accctgcata atttgaagac
    10261 acagcagaaa gggggcttag ggatgaggtc ctggtttttc ttgtataaat aggagtcatg
    10321 ggcgttagtt ctgtagtaat aacttcccag cacctggaca tctcttccag agttatccca
    10381 ctggcttggt gtgtatacat taggggagga taatctgatg ctaacttttt ttttctcttt
    10441 ggttcttgaa tagcttagtt tctttaataa caagtcaaac tttattacaa caataactga
    10501 agttattctt ttaggttctc gtgaaattct cactgaaagc cacattctta gcctaaggca
    10561 tttcatcttt tatgatataa aatgatggct atcaaatgat tttccataca ttgtactgat
    10621 caagttatac acccaggggt atatacactt tcttcatgtt tcttctttgt atatttggtg
    10681 actgtatcgt catagatgta catattgtgt cggtagggct atgaggcatg ttacaggaat
    10741 gtaattttct cagaatttac actcactcgc agtcatttat ttaaaaagat aaaacaagat
    10801 aatgggttct ttgtattggc actttgcacc agaaacatat cattatttat tgatgtgatt
    10861 acttatttgt tatccacctt gtactagtaa gttttagcac tgaattcctt cttcactgtt
    10921 gtttgtattt atgaaattct gaaattatgg ggaatcagcg taatgattaa gttattcatc
    10981 accaggctgt aagcaatatc ttgagtttgt agcttagaat tgggaggata cttaacatct
    11041 ggaagacaag ttcatttcat cttgagatca tggtgaaata ttttggatat ataaattcct
    11101 taagctattg taaccatgtt ttattgcaaa gatgtaaaat atgccagatg tgtgtgagtt
    11161 ggaaatcaaa aaaagaaaaa taaaatatgc aaagaattca
//
