LOCUS       NM_198571               2949 bp    mRNA    linear   PRI 03-OCT-2024
DEFINITION  Homo sapiens N-acetyltransferase 16 (putative) (NAT16), transcript
            variant 1, mRNA.
ACCESSION   NM_198571 XM_351735
VERSION     NM_198571.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 2949)
  AUTHORS   Yamada,S. and Arikawa,S.
  TITLE     An ectotherm homologue of human predicted gene NAT16 encodes
            histidine N-acetyltransferase responsible for
            Nalpha-acetylhistidine synthesis
  JOURNAL   Biochim Biophys Acta 1840 (1), 434-442 (2014)
   PUBMED   24121108
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC004876.2, AK096556.1, BC037583.1 and BU740913.1.
            
            On Nov 22, 2018 this sequence version replaced NM_198571.2.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic and transcript sequence to make the sequence consistent
            with the reference genome assembly. The genomic coordinates used
            for the transcript record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK096556.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA2145743,
                                           SAMEA2154405 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000300303.7/ ENSP00000300303.2
            RefSeq Select criteria :: based on conservation, longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-17                AC004876.2         76312-76328         c
            18-443              AK096556.1         1-426
            444-568             BC037583.1         366-490
            569-1456            AK096556.1         552-1439
            1457-1979           AC004876.2         67501-68023         c
            1980-2948           AK096556.1         1963-2931
            2949-2949           BU740913.1         22-22               c
FEATURES             Location/Qualifiers
     source          1..2949
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="7"
                     /map="7q22.1"
     gene            1..2949
                     /gene="NAT16"
                     /gene_synonym="C7orf52"
                     /note="N-acetyltransferase 16 (putative)"
                     /db_xref="GeneID:375607"
                     /db_xref="HGNC:HGNC:22030"
                     /db_xref="MIM:615783"
     exon            1..252
                     /gene="NAT16"
                     /gene_synonym="C7orf52"
                     /inference="alignment:Splign:2.1.0"
     exon            253..568
                     /gene="NAT16"
                     /gene_synonym="C7orf52"
                     /inference="alignment:Splign:2.1.0"
     CDS             257..1366
                     /gene="NAT16"
                     /gene_synonym="C7orf52"
                     /note="putative N-acetyltransferase C7orf52; putative
                     N-acetyltransferase 16; N-acetyltransferase 16
                     (GCN5-related, putative)"
                     /codon_start=1
                     /product="probable N-acetyltransferase 16"
                     /protein_id="NP_940973.2"
                     /db_xref="CCDS:CCDS5713.1"
                     /db_xref="GeneID:375607"
                     /db_xref="HGNC:HGNC:22030"
                     /db_xref="MIM:615783"
                     /translation="MKLEASCGTATSEVPKPEKKTARDAEPSSETRPQEVEAEPRSGS
                     GPEAEAEPLDFVVATEREFEEVLAISGGIYGGLDYLPSRYHSWLRDPDRTVVLAKRNG
                     GVIALESVNVIDAGETVLVEGLRVAPWERGKGVAGLLQRFCSQLVKRQHPGVKVARLT
                     RDDQLGPRELKKYRLITKQGILLVRFNASALLAGLGARLAALRTSGTFSPLPTEAVSE
                     AGGDVARLLLSPSVQRDVLPGGTIIQDWQPYRPSESNLRLLAAKGLEWRVDSRARPRV
                     LTLCTRPFPIPHGGDGTWRYLNIDAFGSDGAQVQSQLLWHLQRQAPRLVGLNVMCQLF
                     LEPQLWSQLADFCQVGLGLELVKGYTEQYLLEADI"
     exon            569..793
                     /gene="NAT16"
                     /gene_synonym="C7orf52"
                     /inference="alignment:Splign:2.1.0"
     exon            794..2949
                     /gene="NAT16"
                     /gene_synonym="C7orf52"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2928..2933
                     /regulatory_class="polyA_signal_sequence"
                     /gene="NAT16"
                     /gene_synonym="C7orf52"
                     /note="hexamer: AATAAA"
     polyA_site      2949
                     /gene="NAT16"
                     /gene_synonym="C7orf52"
                     /note="major polyA site"
ORIGIN      
        1 gtgccacccg aacccctgaa ccgatgggcg ccccggcccg cgtcgccaac ggagctgcgg
       61 cgctgcccca gcgctgaccg acgttagagt cgggctccga cagcgcggcc gagtccccgc
      121 gcgtcatcct cctttgactc ttgggggctc caaagggacc tctctcttgg caccgggggt
      181 gtctgcgccc gccgcccgcc ccgcttggct ttgcggcatc tcggccctgg ctccagctcc
      241 ggctccggcg agggtcatga agctggaagc cagctgtggc acagccacct cagaggtccc
      301 taagccggaa aagaagactg cccgagatgc agagccaagc tctgaaaccc ggccacagga
      361 ggtggaggcc gagcccaggt cgggatcggg gcctgaggct gaggccgagc cattggactt
      421 cgtggtggcc acggaacggg agtttgagga agtgctggcc atctcggggg gcatctacgg
      481 cggcctggac taccttccta gccgctacca cagctggctc cgggaccccg accgcacggt
      541 ggtgctggcc aagcgcaacg gaggcgtgat cgcgctggag tcggtgaacg tgatcgacgc
      601 cggggagacg gtgctggtgg aggggctgcg cgtggcgccc tgggagcgcg ggaagggcgt
      661 ggccgggctg ctgcagcgct tctgctcgca gctggtcaag agacagcacc cgggggtcaa
      721 ggtggcacgg ctcacccggg acgaccagct gggcccccgg gagctgaaga aataccgcct
      781 aatcaccaag cagggcatcc ttttggtccg attcaacgcg tccgcgctgc tggccgggct
      841 gggcgcgcgg ctggcggcgc tgcggacctc tggcaccttc tcgccgctgc ccaccgaggc
      901 cgtgtccgag gcaggcggcg acgtggcacg cctcctgctg tcaccctccg tgcagcgcga
      961 cgtgcttcca ggcgggacca tcatccagga ctggcagccc taccggccta gcgaaagcaa
     1021 cctgcgcctg ctggcggcca agggcctgga gtggcgcgtg gacagccgcg cgcgcccgcg
     1081 cgtgctcacg ctgtgcacgc gccccttccc catcccgcac ggaggggacg gcacttggcg
     1141 ctatctcaac atcgacgcct tcggtagcga cggcgcgcag gtgcagagcc agctgctgtg
     1201 gcacctgcag cgccaggccc cgcgcctcgt tggcctcaac gtcatgtgcc agctcttcct
     1261 ggagccccag ctgtggtcac agctggctga cttctgccag gtcgggctgg gactggagct
     1321 ggtgaagggt tatactgaac agtacctgct ggaggccgac atctgaggcc tctcctctgg
     1381 cggggagggg gaaaaagacc cgcccccttc cgcagtttcc ccagccagcc tctttcctgc
     1441 catttccgac gctgcgtctc ctgggaagtc ccctctgact cctgccctcc tgcccttacc
     1501 ggcgcaggtc cccccactct gtcccttttg cccttactat cttgcctcta gctcccccaa
     1561 acaccattgc ccactccctg acctgaactt gcggactatt aggtgggggc tgggggtggg
     1621 ggccttgagc tgctgttatc caccctctgt ttttccaaag aactggtccc cgcacaggct
     1681 tcagagtcct tccttccctc tccatcacct cacccggggc gtgaactccc cctttcctgg
     1741 cttctccctt ctgccccctc gtgggtggaa gaactcagga gtgtgtggga tgcccagcct
     1801 cgttcccgag cgcagccgcc caatccgcgt ttcttttctt ccttctgccc tttctaaagc
     1861 cctaaaaact ggtcctgcat tgccctccac accccaatcc cctccccctg ctcaagcttc
     1921 tggtgccaga gatcagtgcc ctctccccac ttctctctag cccctcatcc tcatcctcgc
     1981 tggatctcta cgacgcttaa caccgcagtg cccatttttc tgtccctgtt ttccttccca
     2041 tcaccagccc agtgtgcaat ccagagagag agagagtgat actgtaaaat gaaatgtatt
     2101 tagaatgctc ccccatttgg gtccttgttc atctggtgat gcactttctg agcctgcctc
     2161 tctcactggg gtttcctcct gctttgcaca actttgctat ttcgcaggct cccccgtgcc
     2221 ccagctcacc cgagccgggc ggggtggtgg tggtggtggt ggtgtgtgtg tggtgtggtt
     2281 ctagctgaag agtttggtac agtggagggc gggtccctca gcctggcata ggggctgtct
     2341 cctggttcca accaggccgc cttctagtgc aactggaatt cccacctcct ggtatttctg
     2401 gacaccactc cctttctctg gatcatttat gcttttagaa ctttgagagt cttctattta
     2461 attgcaagta gtaacagctg catctgcaca gcgctgtctc caatactggt tccccacatc
     2521 aaaggcagag ggagaaaaca gaaggctggg aaagatcaaa gtgacttcta agtcattcaa
     2581 agtagctagg agcctcccag cgaatagaac ccgggtgtcc caagcctaga gcatgaccta
     2641 gaacttcact ctgtgggatg atgttagctt gaacttcttg ttgggcaatg cgtaggtgct
     2701 aggagaatgt tgacagtgag tttggggttc gctgggatgg gatccgagat gtgggcagag
     2761 gtggacacca gcaggtggaa gaatgtggac aaggtggggg gtaggggcag ccgccgcttc
     2821 gccactttcc gcagctctgg ttttgctact gtgctgctct ccttgggtgc atcctgtgcc
     2881 tggccacgct gccaccctcc ttgtcacggt gaccacgatt gtatgacaat aaaatggacc
     2941 ttttggcca
//
