LOCUS       NM_024662               3973 bp    mRNA    linear   PRI 12-NOV-2024
DEFINITION  Homo sapiens N-acetyltransferase 10 (NAT10), transcript variant 1,
            mRNA.
ACCESSION   NM_024662
VERSION     NM_024662.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 3973)
  AUTHORS   Li,W.P., Mao,X.T., Xie,J.H., Li,J.Y., Liu,B.Q., Wu,L.X., Yang,B.,
            Li,Y.Y. and Jin,J.
  TITLE     N-acetyltransferase 10 is implicated in the pathogenesis of cycling
            T cell-mediated autoimmune and inflammatory disorders in mice
  JOURNAL   Nat Commun 15 (1), 9388 (2024)
   PUBMED   39477944
  REMARK    GeneRIF: N-acetyltransferase 10 is implicated in the pathogenesis
            of cycling T cell-mediated autoimmune and inflammatory disorders in
            mice.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3973)
  AUTHORS   Xing,P., Zhou,M., Sun,J., Wang,D., Huang,W. and An,P.
  TITLE     NAT10-mediated ac4C acetylation of TFRC promotes sepsis-induced
            pulmonary injury through regulating ferroptosis
  JOURNAL   Mol Med 30 (1), 140 (2024)
   PUBMED   39251905
  REMARK    GeneRIF: NAT10-mediated ac[4]C acetylation of TFRC promotes
            sepsis-induced pulmonary injury through regulating ferroptosis.
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 3973)
  AUTHORS   Song,S., Li,B., Jin,X., Li,H., Wang,H., Wang,F., He,Y. and Zhang,C.
  TITLE     NAT10 Overexpression Promotes Tumorigenesis and
            Epithelial-Mesenchymal Transition Through AKT Pathway in Gastric
            Cancer
  JOURNAL   Dig Dis Sci 69 (9), 3261-3275 (2024)
   PUBMED   38990269
  REMARK    GeneRIF: NAT10 Overexpression Promotes Tumorigenesis and
            Epithelial-Mesenchymal Transition Through AKT Pathway in Gastric
            Cancer.
REFERENCE   4  (bases 1 to 3973)
  AUTHORS   Li,K.J., Hong,Y., Yu,Y.Z., Xie,Z., Lv,D.J., Wang,C., Xie,T.,
            Chen,H., Chen,Z.S., Zeng,J. and Zhao,S.C.
  TITLE     NAT10 Promotes Prostate Cancer Growth and Metastasis by Acetylating
            mRNAs of HMGA1 and KRT8
  JOURNAL   Adv Sci (Weinh) 11 (32), e2310131 (2024)
   PUBMED   38922788
  REMARK    GeneRIF: NAT10 Promotes Prostate Cancer Growth and Metastasis by
            Acetylating mRNAs of HMGA1 and KRT8.
REFERENCE   5  (bases 1 to 3973)
  AUTHORS   Ding,M., Yu,Z., Lu,T., Hu,S., Zhou,X. and Wang,X.
  TITLE     N-acetyltransferase 10 facilitates tumorigenesis of diffuse large
            B-cell lymphoma by regulating AMPK/mTOR signalling through
            N4-acetylcytidine modification of SLC30A9
  JOURNAL   Clin Transl Med 14 (7), e1747 (2024)
   PUBMED   38961519
  REMARK    GeneRIF: N-acetyltransferase 10 facilitates tumorigenesis of
            diffuse large B-cell lymphoma by regulating AMPK/mTOR signalling
            through N4-acetylcytidine modification of SLC30A9.
REFERENCE   6  (bases 1 to 3973)
  AUTHORS   Guan,L.Z., Shen,Q., Sun,Y., Wang,J.C., Gong,Y.L., Hou,L. and
            Zhang,B.
  TITLE     [Nucleolar localization of human acetyltransferase-like protein and
            its expression in tumors]
  JOURNAL   Beijing Da Xue Xue Bao Yi Xue Ban 40 (4), 347-351 (2008)
   PUBMED   18677378
  REMARK    GeneRIF: hALP is a nucleolar protein, and the nucleolar
            localization is mediated by its carboxy terminal domain.
REFERENCE   7  (bases 1 to 3973)
  AUTHORS   Fu,D. and Collins,K.
  TITLE     Purification of human telomerase complexes identifies factors
            involved in telomerase biogenesis and telomere length regulation
  JOURNAL   Mol Cell 28 (5), 773-785 (2007)
   PUBMED   18082603
REFERENCE   8  (bases 1 to 3973)
  AUTHORS   Chi,Y.H., Haller,K., Peloponese,J.M. Jr. and Jeang,K.T.
  TITLE     Histone acetyltransferase hALP and nuclear membrane protein hsSUN1
            function in de-condensation of mitotic chromosomes
  JOURNAL   J Biol Chem 282 (37), 27447-27458 (2007)
   PUBMED   17631499
  REMARK    GeneRIF: chromosome de-condensation needs the function of an inner
            nuclear membrane (INM) protein hsSUN1 and a membrane-associated
            histone acetyltransferase (HAT), hALP.
REFERENCE   9  (bases 1 to 3973)
  AUTHORS   Liu,H., Ling,Y., Gong,Y., Sun,Y., Hou,L. and Zhang,B.
  TITLE     DNA damage induces N-acetyltransferase NAT10 gene expression
            through transcriptional activation
  JOURNAL   Mol Cell Biochem 300 (1-2), 249-258 (2007)
   PUBMED   17180247
  REMARK    GeneRIF: The above results suggested that NAT10 could be involved
            in DNA damage response and increased cellular resistance to
            genotoxicity.
REFERENCE   10 (bases 1 to 3973)
  AUTHORS   Lv,J., Liu,H., Wang,Q., Tang,Z., Hou,L. and Zhang,B.
  TITLE     Molecular cloning of a novel human gene encoding histone
            acetyltransferase-like protein involved in transcriptional
            activation of hTERT
  JOURNAL   Biochem Biophys Res Commun 311 (2), 506-513 (2003)
   PUBMED   14592445
  REMARK    GeneRIF: The investigation suggested that hALP influences the
            activity of histone acetylation and could up-regulate telomerase
            activity through transactivation of hTERT promoter.
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from AC090469.9.
            This sequence is a reference standard in the RefSeqGene project.
            
            On Nov 23, 2018 this sequence version replaced NM_024662.2.
            
            Summary: The protein encoded by this gene is an RNA cytidine
            acetyltransferase involved in histone acetylation, tRNA
            acetylation, the biosynthesis of 18S rRNA, and the enhancement of
            nuclear architecture and chromatin organization. [provided by
            RefSeq, Oct 2016].
            
            Transcript Variant: This variant (1) represents the longer
            transcript and encodes the longer isoform (a).
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK022241.1, BC035558.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1965299, SAMEA1966682
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000257829.8/ ENSP00000257829.3
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-164               AC090469.9         130546-130709       c
            165-287             AC090469.9         128005-128127       c
            288-379             AC090469.9         127505-127596       c
            380-551             AC090469.9         124115-124286       c
            552-674             AC090469.9         122500-122622       c
            675-736             AC090469.9         120454-120515       c
            737-851             AC090469.9         118044-118158       c
            852-959             AC090469.9         117835-117942       c
            960-1093            AC090469.9         113746-113879       c
            1094-1187           AC090469.9         112483-112576       c
            1188-1286           AC090469.9         111938-112036       c
            1287-1423           AC090469.9         108739-108875       c
            1424-1548           AC090469.9         105401-105525       c
            1549-1699           AC090469.9         104807-104957       c
            1700-1796           AC090469.9         104117-104213       c
            1797-1913           AC090469.9         103196-103312       c
            1914-2015           AC090469.9         101918-102019       c
            2016-2090           AC090469.9         101752-101826       c
            2091-2207           AC090469.9         101047-101163       c
            2208-2341           AC090469.9         99563-99696         c
            2342-2390           AC090469.9         99312-99360         c
            2391-2487           AC090469.9         97051-97147         c
            2488-2598           AC090469.9         96843-96953         c
            2599-2771           AC090469.9         95766-95938         c
            2772-2891           AC090469.9         95130-95249         c
            2892-2990           AC090469.9         94521-94619         c
            2991-3064           AC090469.9         93990-94063         c
            3065-3148           AC090469.9         92810-92893         c
            3149-3973           AC090469.9         89430-90254         c
FEATURES             Location/Qualifiers
     source          1..3973
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="11"
                     /map="11p13"
     gene            1..3973
                     /gene="NAT10"
                     /gene_synonym="ALP; Kre33; NET43"
                     /note="N-acetyltransferase 10"
                     /db_xref="GeneID:55226"
                     /db_xref="HGNC:HGNC:29830"
                     /db_xref="MIM:609221"
     exon            1..164
                     /gene="NAT10"
                     /gene_synonym="ALP; Kre33; NET43"
                     /inference="alignment:Splign:2.1.0"
     exon            165..287
                     /gene="NAT10"
                     /gene_synonym="ALP; Kre33; NET43"
                     /inference="alignment:Splign:2.1.0"
     CDS             180..3257
                     /gene="NAT10"
                     /gene_synonym="ALP; Kre33; NET43"
                     /EC_number="2.3.1.-"
                     /note="isoform a is encoded by transcript variant 1;
                     N-acetyltransferase-like protein; 18S rRNA cytosine
                     acetyltransferase; RNA cytidine acetyltransferase;
                     N-acetyltransferase 10 (GCN5-related)"
                     /codon_start=1
                     /product="RNA cytidine acetyltransferase isoform a"
                     /protein_id="NP_078938.3"
                     /db_xref="CCDS:CCDS7889.1"
                     /db_xref="GeneID:55226"
                     /db_xref="HGNC:HGNC:29830"
                     /db_xref="MIM:609221"
                     /translation="MHRKKVDNRIRILIENGVAERQRSLFVVVGDRGKDQVVILHHML
                     SKATVKARPSVLWCYKKELGFSSHRKKRMRQLQKKIKNGTLNIKQDDPFELFIAATNI
                     RYCYYNETHKILGNTFGMCVLQDFEALTPNLLARTVETVEGGGLVVILLRTMNSLKQL
                     YTVTMDVHSRYRTEAHQDVVGRFNERFILSLASCKKCLVIDDQLNILPISSHVATMEA
                     LPPQTPDESLGPSDLELRELKESLQDTQPVGVLVDCCKTLDQAKAVLKFIEGISEKTL
                     RSTVALTAARGRGKSAALGLAIAGAVAFGYSNIFVTSPSPDNLHTLFEFVFKGFDALQ
                     YQEHLDYEIIQSLNPEFNKAVIRVNVFREHRQTIQYIHPADAVKLGQAELVVIDEAAA
                     IPLPLVKSLLGPYLVFMASTINGYEGTGRSLSLKLIQQLRQQSAQSQVSTTAENKTTT
                     TARLASARTLYEVSLQESIRYAPGDAVEKWLNDLLCLDCLNITRIVSGCPLPEACELY
                     YVNRDTLFCYHKASEVFLQRLMALYVASHYKNSPNDLQMLSDAPAHHLFCLLPPVPPT
                     QNALPEVLAVIQVCLEGEISRQSILNSLSRGKKASGDLIPWTVSEQFQDPDFGGLSGG
                     RVVRIAVHPDYQGMGYGSRALQLLQMYYEGRFPCLEEKVLETPQEIHTVSSEAVSLLE
                     EVITPRKDLPPLLLKLNERPAERLDYLGVSYGLTPRLLKFWKRAGFVPVYLRQTPNDL
                     TGEHSCIMLKTLTDEDEADQGGWLAAFWKDFRRRFLALLSYQFSTFSPSLALNIIQNR
                     NMGKPAQPALSREELEALFLPYDLKRLEMYSRNMVDYHLIMDMIPAISRIYFLNQLGD
                     LALSAAQSALLLGIGLQHKSVDQLEKEIELPSGQLMGLFNRIIRKVVKLFNEVQEKAI
                     EEQMVAAKDVVMEPTMKTLSDDLDEAAKEFQEKHKKEVGKLKSMDLSEYIIRGDDEEW
                     NEVLNKAGPNASIISLKSDKKRKLEAKQEPKQSKKLKNRETKNKKDMKLKRKK"
     exon            288..379
                     /gene="NAT10"
                     /gene_synonym="ALP; Kre33; NET43"
                     /inference="alignment:Splign:2.1.0"
     exon            380..551
                     /gene="NAT10"
                     /gene_synonym="ALP; Kre33; NET43"
                     /inference="alignment:Splign:2.1.0"
     exon            552..674
                     /gene="NAT10"
                     /gene_synonym="ALP; Kre33; NET43"
                     /inference="alignment:Splign:2.1.0"
     exon            675..736
                     /gene="NAT10"
                     /gene_synonym="ALP; Kre33; NET43"
                     /inference="alignment:Splign:2.1.0"
     exon            737..851
                     /gene="NAT10"
                     /gene_synonym="ALP; Kre33; NET43"
                     /inference="alignment:Splign:2.1.0"
     exon            852..959
                     /gene="NAT10"
                     /gene_synonym="ALP; Kre33; NET43"
                     /inference="alignment:Splign:2.1.0"
     exon            960..1093
                     /gene="NAT10"
                     /gene_synonym="ALP; Kre33; NET43"
                     /inference="alignment:Splign:2.1.0"
     exon            1094..1187
                     /gene="NAT10"
                     /gene_synonym="ALP; Kre33; NET43"
                     /inference="alignment:Splign:2.1.0"
     exon            1188..1286
                     /gene="NAT10"
                     /gene_synonym="ALP; Kre33; NET43"
                     /inference="alignment:Splign:2.1.0"
     exon            1287..1423
                     /gene="NAT10"
                     /gene_synonym="ALP; Kre33; NET43"
                     /inference="alignment:Splign:2.1.0"
     exon            1424..1548
                     /gene="NAT10"
                     /gene_synonym="ALP; Kre33; NET43"
                     /inference="alignment:Splign:2.1.0"
     exon            1549..1699
                     /gene="NAT10"
                     /gene_synonym="ALP; Kre33; NET43"
                     /inference="alignment:Splign:2.1.0"
     exon            1700..1796
                     /gene="NAT10"
                     /gene_synonym="ALP; Kre33; NET43"
                     /inference="alignment:Splign:2.1.0"
     exon            1797..1913
                     /gene="NAT10"
                     /gene_synonym="ALP; Kre33; NET43"
                     /inference="alignment:Splign:2.1.0"
     exon            1914..2015
                     /gene="NAT10"
                     /gene_synonym="ALP; Kre33; NET43"
                     /inference="alignment:Splign:2.1.0"
     exon            2016..2090
                     /gene="NAT10"
                     /gene_synonym="ALP; Kre33; NET43"
                     /inference="alignment:Splign:2.1.0"
     exon            2091..2207
                     /gene="NAT10"
                     /gene_synonym="ALP; Kre33; NET43"
                     /inference="alignment:Splign:2.1.0"
     exon            2208..2341
                     /gene="NAT10"
                     /gene_synonym="ALP; Kre33; NET43"
                     /inference="alignment:Splign:2.1.0"
     exon            2342..2390
                     /gene="NAT10"
                     /gene_synonym="ALP; Kre33; NET43"
                     /inference="alignment:Splign:2.1.0"
     exon            2391..2487
                     /gene="NAT10"
                     /gene_synonym="ALP; Kre33; NET43"
                     /inference="alignment:Splign:2.1.0"
     exon            2488..2598
                     /gene="NAT10"
                     /gene_synonym="ALP; Kre33; NET43"
                     /inference="alignment:Splign:2.1.0"
     exon            2599..2771
                     /gene="NAT10"
                     /gene_synonym="ALP; Kre33; NET43"
                     /inference="alignment:Splign:2.1.0"
     exon            2772..2891
                     /gene="NAT10"
                     /gene_synonym="ALP; Kre33; NET43"
                     /inference="alignment:Splign:2.1.0"
     exon            2892..2990
                     /gene="NAT10"
                     /gene_synonym="ALP; Kre33; NET43"
                     /inference="alignment:Splign:2.1.0"
     exon            2991..3064
                     /gene="NAT10"
                     /gene_synonym="ALP; Kre33; NET43"
                     /inference="alignment:Splign:2.1.0"
     exon            3065..3148
                     /gene="NAT10"
                     /gene_synonym="ALP; Kre33; NET43"
                     /inference="alignment:Splign:2.1.0"
     exon            3149..3973
                     /gene="NAT10"
                     /gene_synonym="ALP; Kre33; NET43"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3952..3957
                     /regulatory_class="polyA_signal_sequence"
                     /gene="NAT10"
                     /gene_synonym="ALP; Kre33; NET43"
                     /note="hexamer: AATAAA"
     polyA_site      3973
                     /gene="NAT10"
                     /gene_synonym="ALP; Kre33; NET43"
                     /note="major polyA site"
ORIGIN      
        1 agttcctgag agggacgcgt gccgcggagc caggcttact acgtgacccg gacaccaggc
       61 atacgctagg ggcagtcagc tgtgccttct ctttcggagt tgttccgtgc tcccacgtgc
      121 ttccccttct ccactggctg ggatcccccg ggctcggggc gcagtaataa tttttcacca
      181 tgcatcggaa aaaggtggat aaccgaatcc ggattctcat tgagaatgga gtagctgagc
      241 ggcaaagatc tctctttgtt gtagttgggg atcgaggaaa agatcaggtg gtaatacttc
      301 atcacatgtt atccaaagca actgtgaagg ctcggccttc agtgctgtgg tgttataaga
      361 aagagctggg gtttagcagt caccggaaga aaagaatgcg acagctgcag aagaaaataa
      421 agaatggaac actgaacata aagcaggacg acccctttga actcttcata gcagccacaa
      481 acattcgcta ctgctactac aacgagaccc acaagatcct gggcaatacc ttcggcatgt
      541 gtgtgctgca ggattttgaa gccttaactc caaacttgct ggccaggact gtagaaacag
      601 tggaaggtgg tgggctagtg gtcatcctcc tacggaccat gaactcactc aagcaattgt
      661 acacagtgac tatggatgtg cattccaggt acagaactga ggcccatcag gatgtggtgg
      721 gaagatttaa tgaaaggttt attctgtctc tggcctcttg taagaagtgt ctcgtcattg
      781 atgaccagct caacatcctg cccatctcct cccacgttgc caccatggag gccctgcctc
      841 cccagactcc ggatgagagt cttggtcctt ctgatctgga gctgagggag ttgaaggaga
      901 gcttgcagga cacccagcct gtgggtgtgt tggtggactg ctgtaagact ctagaccagg
      961 ccaaagctgt cttgaaattt atcgagggca tctctgaaaa gaccctgagg agtactgttg
     1021 cactcacagc tgctcgagga cggggaaaat ctgcagccct gggattggcg attgctgggg
     1081 cggtggcatt tgggtactcc aatatctttg ttacctcccc aagccctgat aacctccata
     1141 ctctgtttga atttgtattt aaaggatttg atgctctgca atatcaggaa catctggatt
     1201 atgagattat ccagtctcta aatcctgaat ttaacaaagc agtgatcaga gtgaatgtat
     1261 ttcgagaaca caggcagact attcagtata tacatcctgc agatgctgtg aagctgggcc
     1321 aggctgaact agttgtgatt gatgaagctg ccgccatccc cctccccttg gtgaagagcc
     1381 tacttggccc ctaccttgtt ttcatggcat ccaccatcaa tggctatgag ggcactggcc
     1441 ggtcactgtc cctcaagcta attcagcagc tccgtcaaca gagcgcccag agccaggtca
     1501 gcaccactgc tgagaataag accacgacga cagccagatt ggcatcagcg cggacactgt
     1561 atgaggtttc cctccaggag tcaatccgat acgcccctgg ggatgcagtg gagaagtggc
     1621 tgaatgactt gctgtgcctg gattgcctca acatcactcg gatagtctca ggctgcccct
     1681 tgcctgaagc ttgtgaactg tactatgtta atagagatac cctcttttgc taccacaagg
     1741 cctctgaagt tttcctccaa cggcttatgg ccctctacgt ggcttctcac tacaagaact
     1801 ctcccaatga tctccagatg ctctccgatg cacctgctca ccatctcttc tgccttctgc
     1861 ctcccgtgcc ccccacccag aatgcccttc cagaagtgct tgctgttatc caggtgtgcc
     1921 ttgaagggga gatttctcgc cagtccatct tgaacagtct gtctcgaggc aagaaggctt
     1981 caggggacct gattccatgg acagtgtcag aacagttcca agatccagac tttggtggtc
     2041 tgtctggtgg aagggtcgtt cgcattgctg ttcacccaga ttatcaaggg atgggctatg
     2101 gcagccgtgc tctgcagctg ctgcagatgt actatgaagg caggtttcct tgtctggagg
     2161 aaaaggtcct tgagacacca caggaaattc acaccgtaag cagcgaggct gtcagcttgt
     2221 tggaagaggt catcactccc cggaaggacc tgcctccttt actcctcaaa ttgaatgaga
     2281 ggcctgccga acgcctggat tacctgggtg tttcctatgg cttgaccccc aggctcctca
     2341 agttctggaa acgagctgga tttgttcctg tttatctgag acagaccccg aatgacctga
     2401 ccggagagca ctcgtgcatc atgctgaaga cgctcactga tgaggatgag gctgaccagg
     2461 gaggctggct tgcagccttc tggaaagatt tccgacggcg gttcctagcc ttgctctcct
     2521 accagttcag taccttctct ccttccctgg ctctgaacat cattcagaac aggaacatgg
     2581 ggaagccagc ccagcctgcc ctgagccggg aggagctgga agcactcttc ctcccctatg
     2641 acctgaagcg gctggagatg tattcacgga atatggtgga ctatcacctc atcatggaca
     2701 tgatcccggc catctctcgc atctatttcc tgaaccagct gggggacctg gccctgtctg
     2761 cggctcagtc ggctcttctc ttggggattg gcctgcagca taagtctgtg gaccagctgg
     2821 aaaaggagat tgagctgccc tcgggccagt tgatgggact tttcaaccgg atcatccgca
     2881 aagttgtgaa gctatttaat gaagttcagg aaaaggccat tgaggagcag atggtggcag
     2941 cgaaggatgt ggtcatggag cccacgatga agaccctcag tgacgaccta gatgaagcag
     3001 caaaggaatt tcaggagaaa cacaagaagg aagtagggaa gctgaagagc atggacctct
     3061 ctgaatacat aatccgtggg gacgatgaag agtggaatga agttttgaac aaagctgggc
     3121 cgaacgcctc gatcatcagc ctgaaaagtg acaagaaaag gaagttagag gccaaacaag
     3181 aacccaaaca gagcaagaag ttgaagaaca gagagacaaa gaacaaaaaa gatatgaaac
     3241 tgaagcggaa gaaatagtga agagaaactc gggcatctgt gtttgatcat gggaagatac
     3301 tctcactaac tgaaccctct ctggctggac tgttaaaagc aacgagaggc cccggcacac
     3361 ctggaagctg gccgcgaatt cggcctctgg gcctgtgtgt ctgtgagctc aacctggcta
     3421 aaggcagagt cactcccaaa tgggtctctt tagaacttga tggctgggca ctgccatctc
     3481 tagaattgcc acgagtctct ctcttcctgc ccagtccagg gccctccttt cctataagtt
     3541 catattttgc tttgagccag ctttttagtc tcattcccac acatgtggaa gccacgttgc
     3601 ctctcgaccg cctgaggccc ttaagtacat cgctttctgg tggtgcccag gaggctgctg
     3661 ctgggccgct gggtctctct ttgtggactt gtacctggag caggaggaac tccagtccgt
     3721 cccggcatcc atggcagccc gcggttaggt gcgccagggt ttgctgatgt tgtcttgtgc
     3781 tgttccactc ttggctccag cagacccact gtcccagaaa agcctgatcc tgtagtttat
     3841 gtagaatgcc acatctgcgt cctcaagacc tgtttcatcc atttgggaaa agatgttggg
     3901 aaaggccact ttgctcgcag gggtgagggg aaggatagag aatctatttt taataaataa
     3961 cattctagaa aga
//
