LOCUS       NM_001145465             907 bp    mRNA    linear   PRI 01-JUN-2024
DEFINITION  Homo sapiens NANOG neighbor homeobox (NANOGNB), mRNA.
ACCESSION   NM_001145465 XR_040558 XR_040559 XR_040560
VERSION     NM_001145465.1
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 907)
  AUTHORS   Lovering,R.C., Gaudet,P., Acencio,M.L., Ignatchenko,A., Jolma,A.,
            Fornes,O., Kuiper,M., Kulakovskiy,I.V., Laegreid,A., Martin,M.J.
            and Logie,C.
  TITLE     A GO catalogue of human DNA-binding transcription factors
  JOURNAL   Biochim Biophys Acta Gene Regul Mech 1864 (11-12), 194765 (2021)
   PUBMED   34673265
REFERENCE   2  (bases 1 to 907)
  AUTHORS   Dunwell,T.L. and Holland,P.W.H.
  TITLE     A sister of NANOG regulates genes expressed in pre-implantation
            human development
  JOURNAL   Open Biol 7 (4) (2017)
   PUBMED   28446706
REFERENCE   3  (bases 1 to 907)
  AUTHORS   Zhong,Y.F. and Holland,P.W.
  TITLE     The dynamics of vertebrate homeobox gene evolution: gain and loss
            of genes in mouse and human lineages
  JOURNAL   BMC Evol Biol 11, 169 (2011)
   PUBMED   21679462
  REMARK    Erratum:[BMC Evol Biol. 2011;11:204]
            Publication Status: Online-Only
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AY151139.1.
            
            On or before Mar 1, 2009 this sequence version replaced
            XR_040559.1, XR_040560.1, XR_040558.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AY151139.1, BI464932.1 [ECO:0000332]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000382119.1/ ENSP00000371553.1
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-907               AY151139.1         1-907
FEATURES             Location/Qualifiers
     source          1..907
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="12"
                     /map="12p13.31"
     gene            1..907
                     /gene="NANOGNB"
                     /note="NANOG neighbor homeobox"
                     /db_xref="GeneID:360030"
                     /db_xref="HGNC:HGNC:24958"
                     /db_xref="MIM:620692"
     exon            1..172
                     /gene="NANOGNB"
                     /inference="alignment:Splign:2.1.0"
     CDS             71..637
                     /gene="NANOGNB"
                     /note="homeobox protein C14; homeobox C14"
                     /codon_start=1
                     /product="NANOG neighbor homeobox"
                     /protein_id="NP_001138937.1"
                     /db_xref="CCDS:CCDS44826.1"
                     /db_xref="GeneID:360030"
                     /db_xref="HGNC:HGNC:24958"
                     /db_xref="MIM:620692"
                     /translation="MHRARWLTPVIPALWEAEAGRSRGQEIETILANKKQSAMPWDQD
                     PEQSTGNYSEDEQNGKQKWREEGEAGRKREREKEEKNEKELQDEQENKRKRENEKQKQ
                     YPEKRLVSKSLMHTLWAKFKLNRCPTIQESLSLSFEFDMTHKQISQWFCKTRKKYNKE
                     MSKRKHKKKHMRWRSLCCQGWSRTPALK"
     exon            173..505
                     /gene="NANOGNB"
                     /inference="alignment:Splign:2.1.0"
     exon            506..585
                     /gene="NANOGNB"
                     /inference="alignment:Splign:2.1.0"
     exon            586..907
                     /gene="NANOGNB"
                     /inference="alignment:Splign:2.1.0"
     regulatory      726..731
                     /regulatory_class="polyA_signal_sequence"
                     /gene="NANOGNB"
                     /note="hexamer: AATAAA"
     polyA_site      754
                     /gene="NANOGNB"
                     /note="major polyA site"
ORIGIN      
        1 atctacctta tctggtcggt catctctgta acctccctac caaggactaa ttggtcttta
       61 aaactcctca atgcaccggg cgcggtggct cacgcctgta atcccagcac tttgggaggc
      121 cgaggcgggc agatcacgag gtcaggaaat cgagaccatc ttggctaaca agaaacaatc
      181 agctatgcct tgggatcaag atccagaaca atcaactgga aattacagtg aagatgaaca
      241 aaatggaaag cagaaatgga gagaagaagg agaagcaggc agaaagagag aacgagaaaa
      301 agaagaaaaa aacgaaaagg agctgcaaga tgaacaggaa aacaaaagga aaagggaaaa
      361 tgagaaacag aaacagtatc ccgagaaaag attagtcagc aaatccctca tgcatactct
      421 ctgggcaaag tttaagttaa acaggtgccc cactatacaa gagagtctat cactgtcatt
      481 tgaatttgac atgacacata aacagataag tcaatggttt tgtaaaacga ggaagaaata
      541 taataaagaa atgtccaaga gaaagcataa gaaaaaacat atgagatgga gatctctgtg
      601 ttgccaaggc tggtctcgaa ctcctgccct caagtgatct tcctattttg gcctccagaa
      661 atgctgtgat tacaagcatg agccatcgca ctggctaaga cattttacat gacaccattc
      721 tcaccaataa atggagttct gaaaggataa acaagaaaac attaacagtc gttgattccg
      781 tggagtagaa ctaaatgagg ggtatgcaaa ggagttttta tgtgttttat ttttacccta
      841 ctgtagattt aaagttttta taatggatgt taattgattt tatttaagaa aaaaaatcga
      901 gtcaagg
//
