LOCUS       NM_001080396            9264 bp    mRNA    linear   PRI 04-APR-2024
DEFINITION  Homo sapiens NALCN channel auxiliary factor 1 (NALF1), mRNA.
ACCESSION   NM_001080396 XM_001128712
VERSION     NM_001080396.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 9264)
  AUTHORS   Xie,J., Ke,M., Xu,L., Lin,S., Huang,J., Zhang,J., Yang,F., Wu,J.
            and Yan,Z.
  TITLE     Structure of the human sodium leak channel NALCN in complex with
            FAM155A
  JOURNAL   Nat Commun 11 (1), 5831 (2020)
   PUBMED   33203861
  REMARK    GeneRIF: Structure of the human sodium leak channel NALCN in
            complex with FAM155A.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9264)
  AUTHORS   Kschonsak,M., Chua,H.C., Noland,C.L., Weidling,C., Clairfeuille,T.,
            Bahlke,O.O., Ameen,A.O., Li,Z.R., Arthur,C.P., Ciferri,C.,
            Pless,S.A. and Payandeh,J.
  TITLE     Structure of the human sodium leak channel NALCN
  JOURNAL   Nature 587 (7833), 313-318 (2020)
   PUBMED   32698188
  REMARK    GeneRIF: Structure of the human sodium leak channel NALCN.
REFERENCE   3  (bases 1 to 9264)
  AUTHORS   Chua,H.C., Wulf,M., Weidling,C., Rasmussen,L.P. and Pless,S.A.
  TITLE     The NALCN channel complex is voltage sensitive and directly
            modulated by extracellular calcium
  JOURNAL   Sci Adv 6 (17), eaaz3154 (2020)
   PUBMED   32494638
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 9264)
  AUTHORS   Reichert,M.C., Kupcinskas,J., Schulz,A., Schramm,C., Weber,S.N.,
            Krawczyk,M., Jungst,C., Casper,M., Grunhage,F., Appenrodt,B.,
            Zimmer,V., Tamelis,A., Lukosiene,J.I., Pauziene,N., Kiudelis,G.,
            Jonaitis,L., Goeser,T., Malinowski,M., Glanemann,M., Kupcinskas,L.
            and Lammert,F.
  TITLE     Common variation in FAM155A is associated with diverticulitis but
            not diverticulosis
  JOURNAL   Sci Rep 10 (1), 1658 (2020)
   PUBMED   32015353
  REMARK    GeneRIF: Common variation in FAM155A is associated with
            diverticulitis but not diverticulosis.
            Publication Status: Online-Only
REFERENCE   5  (bases 1 to 9264)
  AUTHORS   Huang,G.H., Du,L., Li,N., Zhang,Y., Xiang,Y., Tang,J.H., Xia,S.,
            Zhang,E.E. and Lv,S.Q.
  TITLE     Methylation-mediated miR-155-FAM133A axis contributes to the
            attenuated invasion and migration of IDH mutant gliomas
  JOURNAL   Cancer Lett 432, 93-102 (2018)
   PUBMED   29885519
  REMARK    GeneRIF: Low FAM155A expression is associated with glioma.
REFERENCE   6  (bases 1 to 9264)
  AUTHORS   Comuzzie,A.G., Cole,S.A., Laston,S.L., Voruganti,V.S., Haack,K.,
            Gibbs,R.A. and Butte,N.F.
  TITLE     Novel genetic loci identified for the pathophysiology of childhood
            obesity in the Hispanic population
  JOURNAL   PLoS One 7 (12), e51954 (2012)
   PUBMED   23251661
REFERENCE   7  (bases 1 to 9264)
  AUTHORS   Wang,K., Zhang,H., Bloss,C.S., Duvvuri,V., Kaye,W., Schork,N.J.,
            Berrettini,W. and Hakonarson,H.
  CONSRTM   Price Foundation Collaborative Group
  TITLE     A genome-wide association study on common SNPs and rare CNVs in
            anorexia nervosa
  JOURNAL   Mol Psychiatry 16 (9), 949-959 (2011)
   PUBMED   21079607
REFERENCE   8  (bases 1 to 9264)
  AUTHORS   Terracciano,A., Tanaka,T., Sutin,A.R., Sanna,S., Deiana,B., Lai,S.,
            Uda,M., Schlessinger,D., Abecasis,G.R., Ferrucci,L. and Costa,P.T.
            Jr.
  TITLE     Genome-wide association scan of trait depression
  JOURNAL   Biol Psychiatry 68 (9), 811-817 (2010)
   PUBMED   20800221
REFERENCE   9  (bases 1 to 9264)
  AUTHORS   Anney,R.J., Lasky-Su,J., O'Dushlaine,C., Kenny,E., Neale,B.M.,
            Mulligan,A., Franke,B., Zhou,K., Chen,W., Christiansen,H.,
            Arias-Vasquez,A., Banaschewski,T., Buitelaar,J., Ebstein,R.,
            Miranda,A., Mulas,F., Oades,R.D., Roeyers,H., Rothenberger,A.,
            Sergeant,J., Sonuga-Barke,E., Steinhausen,H., Asherson,P.,
            Faraone,S.V. and Gill,M.
  TITLE     Conduct disorder and ADHD: evaluation of conduct problems as a
            categorical and quantitative trait in the international multicentre
            ADHD genetics study
  JOURNAL   Am J Med Genet B Neuropsychiatr Genet 147B (8), 1369-1378 (2008)
   PUBMED   18951430
REFERENCE   10 (bases 1 to 9264)
  AUTHORS   Li,S.H., McInnis,M.G., Margolis,R.L., Antonarakis,S.E. and
            Ross,C.A.
  TITLE     Novel triplet repeat containing genes in human brain: cloning,
            expression, and length polymorphisms
  JOURNAL   Genomics 16 (3), 572-579 (1993)
   PUBMED   8325628
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL136964.8, DA779672.1, BC157855.1, AL445204.3, AW592075.1 and
            N69765.1.
            
            On May 17, 2019 this sequence version replaced NM_001080396.2.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1660809.12606.1,
                                           SRR1660805.143535.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1968968, SAMEA1970526
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000375915.4/ ENSP00000365080.1
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-384               AL136964.8         153794-154177       c
            385-824             DA779672.1         145-584
            825-2971            BC157855.1         42-2188
            2972-3841           AL445204.3         91866-92735         c
            3842-4234           AW592075.1         1-393               c
            4235-4243           N69765.1           1-9                 c
            4244-9264           AL445204.3         86443-91463         c
FEATURES             Location/Qualifiers
     source          1..9264
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="13"
                     /map="13q33.3"
     gene            1..9264
                     /gene="NALF1"
                     /gene_synonym="FAM155A; NLF-1; NLF1"
                     /note="NALCN channel auxiliary factor 1"
                     /db_xref="GeneID:728215"
                     /db_xref="HGNC:HGNC:33877"
                     /db_xref="MIM:619899"
     exon            1..1815
                     /gene="NALF1"
                     /gene_synonym="FAM155A; NLF-1; NLF1"
                     /inference="alignment:Splign:2.1.0"
     CDS             901..2277
                     /gene="NALF1"
                     /gene_synonym="FAM155A; NLF-1; NLF1"
                     /note="transmembrane protein FAM155A; family with sequence
                     similarity 155 member A"
                     /codon_start=1
                     /product="NALCN channel auxiliary factor 1"
                     /protein_id="NP_001073865.1"
                     /db_xref="CCDS:CCDS32006.1"
                     /db_xref="GeneID:728215"
                     /db_xref="HGNC:HGNC:33877"
                     /db_xref="MIM:619899"
                     /translation="MTRGAWMCRQYDDGLKIWLAAPRENEKPFIDSERAQKWRLSLAS
                     LLFFTVLLSDHLWFCAEAKLTRARDKEHQQQQRQQQQQQQQQRQRQQQQQQRRQQEPS
                     WPALLASMGESSPAAQAHRLLSASSSPTLPPSPGDGGGGGGKGNRGKDDRGKALFLGN
                     SAKPVWRLETCYPQGASSGQCFTVENADAVCARNWSRGAAGGDGQEVRSKHPTPLWNL
                     SDFYLSFCNSYTLWELFSGLSSPNTLNCSLDVVLKEGGEMTTCRQCVEAYQDYDHHAQ
                     EKYEEFESVLHKYLQSEEYSVKSCPEDCKIVYKAWLCSQYFEVTQFNCRKTIPCKQYC
                     LEVQTRCPFILPDNDEVIYGGLSSFICTGLYETFLTNDEPECCDVRREEKSNNPSKGT
                     VEKSGSCHRTSLTVSSATRLCNSRLKLCVLVLILLHTVLTASAAQNTAGLSFGGINTL
                     EENSTNEE"
     exon            1816..1987
                     /gene="NALF1"
                     /gene_synonym="FAM155A; NLF-1; NLF1"
                     /inference="alignment:Splign:2.1.0"
     exon            1988..9264
                     /gene="NALF1"
                     /gene_synonym="FAM155A; NLF-1; NLF1"
                     /inference="alignment:Splign:2.1.0"
     regulatory      4091..4096
                     /regulatory_class="polyA_signal_sequence"
                     /gene="NALF1"
                     /gene_synonym="FAM155A; NLF-1; NLF1"
                     /note="hexamer: AATAAA"
     polyA_site      4113
                     /gene="NALF1"
                     /gene_synonym="FAM155A; NLF-1; NLF1"
                     /note="major polyA site"
     regulatory      4212..4217
                     /regulatory_class="polyA_signal_sequence"
                     /gene="NALF1"
                     /gene_synonym="FAM155A; NLF-1; NLF1"
                     /note="hexamer: AATACA"
     regulatory      4224..4229
                     /regulatory_class="polyA_signal_sequence"
                     /gene="NALF1"
                     /gene_synonym="FAM155A; NLF-1; NLF1"
                     /note="hexamer: AAGAAA"
     polyA_site      4239
                     /gene="NALF1"
                     /gene_synonym="FAM155A; NLF-1; NLF1"
     polyA_site      4246
                     /gene="NALF1"
                     /gene_synonym="FAM155A; NLF-1; NLF1"
     regulatory      5786..5791
                     /regulatory_class="polyA_signal_sequence"
                     /gene="NALF1"
                     /gene_synonym="FAM155A; NLF-1; NLF1"
                     /note="hexamer: ATTAAA"
     polyA_site      5816
                     /gene="NALF1"
                     /gene_synonym="FAM155A; NLF-1; NLF1"
     regulatory      6258..6263
                     /regulatory_class="polyA_signal_sequence"
                     /gene="NALF1"
                     /gene_synonym="FAM155A; NLF-1; NLF1"
                     /note="hexamer: ATTAAA"
     polyA_site      6280
                     /gene="NALF1"
                     /gene_synonym="FAM155A; NLF-1; NLF1"
     regulatory      7189..7194
                     /regulatory_class="polyA_signal_sequence"
                     /gene="NALF1"
                     /gene_synonym="FAM155A; NLF-1; NLF1"
                     /note="hexamer: AATAAA"
     polyA_site      7214
                     /gene="NALF1"
                     /gene_synonym="FAM155A; NLF-1; NLF1"
     regulatory      9106..9111
                     /regulatory_class="polyA_signal_sequence"
                     /gene="NALF1"
                     /gene_synonym="FAM155A; NLF-1; NLF1"
                     /note="hexamer: AATAAA"
     polyA_site      9129
                     /gene="NALF1"
                     /gene_synonym="FAM155A; NLF-1; NLF1"
     regulatory      9227..9232
                     /regulatory_class="polyA_signal_sequence"
                     /gene="NALF1"
                     /gene_synonym="FAM155A; NLF-1; NLF1"
                     /note="hexamer: AATACA"
     regulatory      9236..9241
                     /regulatory_class="polyA_signal_sequence"
                     /gene="NALF1"
                     /gene_synonym="FAM155A; NLF-1; NLF1"
                     /note="hexamer: ATTAAA"
     polyA_site      9245
                     /gene="NALF1"
                     /gene_synonym="FAM155A; NLF-1; NLF1"
     polyA_site      9264
                     /gene="NALF1"
                     /gene_synonym="FAM155A; NLF-1; NLF1"
ORIGIN      
        1 aaaaaagtgt ttctccagga cgaagatggc ggcaacttag cccgcggact gaagatgact
       61 gtggctctcg ggaggcccag cccaggcgat tcggcccgga gctccgcggg aggcggcgtc
      121 agcagtcgga gccccggcgg cggcgcccgc gggcggccct gcggcagcgg cggcggcggc
      181 ggcggcggcg gcagcactta gagcgcgggg tggggggtgg gggggaggga gcgccccgcc
      241 ggaggcagcc caggctccgg actctgggag agccagcgcg gagcaggagc gggaggcgga
      301 ggagaagaag aaggagaagg aaaggaagga ggaggaagag gaggagaaga agaggaggag
      361 gaggaggagg aggggaggcg ctccgggcgc cgtcagtggg cagcggaggc gcggcatgcc
      421 cctggcaggg gagagcgggc tgggctccgc ggggccatgg ggacccgcgc gctgacaatg
      481 cctgggtgac cggagccgcg ccagccaccc tgtcacctcc accatcgccc cctgcaccca
      541 gcctcgccgc cggccaccag caccagcctc ctccgtctct ctctctctct ctctctccat
      601 tattgtttcc cactctacag aggatggggt cggctgatga ttaggaagca agtcagacct
      661 tccttcaaag cctggtaata tttatgtagg caaaagagac agagagagat aaaagagagg
      721 gagagggaga gagagagaga ggagagaggg agaggggaag agagagaaag agagagagga
      781 gagagaagaa acgggaggag gggataagga aattaaaccc tttaagtcaa tgcatattgt
      841 ggtgacaccg gcacaggcgc cctcacggtg gagtcggcca gggctgtgcg ttcccaaaat
      901 atgaccaggg gtgcttggat gtgtcggcag tatgacgacg gcttaaaaat ctggttggca
      961 gcaccccgag agaacgagaa accgttcatc gattccgaga gggctcagaa atggcgactg
     1021 tctctggcat ctctcttgtt tttcacagtc ctgctctctg atcacttgtg gttctgcgcc
     1081 gaggccaagc tgacccgggc ccgggacaag gagcaccagc agcagcagcg gcagcagcag
     1141 cagcagcagc agcagcagag gcagcggcag cagcagcagc agcagcggcg gcagcaggag
     1201 ccctcctggc ccgcgctcct ggcgagcatg ggggagtcct cgcccgccgc ccaggcacac
     1261 agactcctct ccgcctcctc gtcccccacc ctgcccccct ccccgggaga cggcggcggc
     1321 ggcggcggca agggcaaccg aggcaaagac gaccggggca aggctctttt tctaggaaac
     1381 tctgccaagc ccgtgtggcg cctggagact tgttaccccc agggcgcgtc ctcgggccag
     1441 tgcttcacgg tggagaatgc ggacgcggtg tgcgccagga actggagtcg gggggcggcc
     1501 gggggggacg ggcaggaggt gaggagcaag catcccactc cgctctggaa cttgtcggat
     1561 ttttaccttt cgttttgtaa ttcctacaca ctttgggagt tgttctcggg gttgtccagt
     1621 cccaacactt tgaactgcag tctggatgtg gtgctcaagg aaggcggcga gatgaccact
     1681 tgcaggcagt gcgtcgaggc ttaccaggac tatgaccacc atgctcagga gaaatacgaa
     1741 gagtttgaaa gcgtgctcca caaatattta cagtcggagg agtactcggt gaaatcctgt
     1801 cctgaagact gtaagattgt ctacaaagcc tggctctgtt cccagtattt tgaagtcaca
     1861 cagtttaact gcagaaagac aattccttgc aagcaatact gtttggaggt tcagacgagg
     1921 tgtccattta tattgcccga caatgatgaa gtcatctacg gaggcctctc cagtttcatc
     1981 tgtacagggc tttatgaaac ctttctaacc aatgatgaac cagaatgctg tgacgtcagg
     2041 agagaagaaa aatcaaataa cccatccaaa gggaccgtag agaaaagtgg ctcctgtcac
     2101 aggacatcgc tcacagtgtc atcagcaaca agactgtgca acagcagact caagctgtgt
     2161 gttcttgtac tgattctctt acacacagtg ctcacagcct cggcagcaca gaacacagcc
     2221 ggactgagct ttggaggcat caacacgctg gaagaaaact caaccaatga ggagtaacgg
     2281 aaggacgagt gtcaccacag cagcagctgg cccgccgtga aaaatggcaa ctgctgtctc
     2341 atgtaacaga aactgggtgc ttttaccctc gaattactta ttgcaaggcc tttagggtaa
     2401 aatttaaaca gatgggcctg aatccaaaca aggacacaac cacagctttt tattgactaa
     2461 aaggctggaa agtgacttta aatttctcac accattttat acactgtgtt ttaatgtttg
     2521 gaggttttat ttgctttcgt tttggtttgg gtttatttgt ttgtttattt tttgcacttg
     2581 ttaatacagg atttattttg ggggatggtt tctcagaggt aaactaagtc ttttcactgt
     2641 ctctatctct ctatatattt ctagtcattg tgtgtgttca tcagatagtt ctgtctttat
     2701 gtcctgtcag cttctattag aggaatgatt gctatgacct catggtatag caaaaaacaa
     2761 caacaaaaaa agaataaaaa ataaaaaaga caaaaaaaag aaaacaacaa aaaaataaaa
     2821 ataaaaaaaa tccctaagtc tcccttctac ccacagaacc aacaacaccc ttcccggcct
     2881 ttcctttccc tcgccctctt ctcgtcccct aagcaaacaa catccgcttg cttctgtctg
     2941 tgtaaccaca gtgaatgggt gtgcacgctt ggtgggcctc tgagcccctg ttgcacaaac
     3001 cagaaacaga gcggagccaa gggggcctga caagagttcc tttttagctg aacaaacaag
     3061 tgctctccat aataggtgga atcagacagt taacacattt ttatgttgaa aacaaaataa
     3121 aaggaaaaaa ttaaaaaaaa ctatcatgaa ctgtattgct ccagttccca tccccaagtg
     3181 gcccagccct ttcttgctgg tccagttgga caggagcagc tatctagaat caggatgcgg
     3241 ggagtgagga agtttttctt ttgacaatga aggtgggctt tcattgtgat ttttgttctg
     3301 ttgcagtaat ataggagcac attttggcca ttgtaattac agggaacaaa caaagggatt
     3361 gcggacacat atctggactt cttttcctcc cttattgttg tggaagagac actagaaatg
     3421 ctcaaacacc tgcaatatac agaatataca caattttatt ccagtatttc cctaacatat
     3481 ggtttaaaat tattccaggt atacagtgta tgcaattctg cattatcaca gaggaacaac
     3541 ttctttttta aaaaataaat aggtcagcca tttttattaa cgtgcaaaaa ctttatcact
     3601 ctaacatgct ctaggtagtt gaggaaaaga ggtctgatca ctgtttgtat tttattttct
     3661 ttgtgggaac atttcacctg ctgagtgtac atgaatttgc tttctataaa aggcttttat
     3721 gagtttacag tagaatcagt ggaaggaaga gttaataagg gctgttttta aaaaaacaaa
     3781 caaacaaaca aaacaaataa ttaaaaaaaa aattttacat tccttcctat tctctaacta
     3841 cacttgggaa gtgcacttca gataagtttg cagtgtgact gagagatgaa ggaaatccat
     3901 agaaaaggtc ctcttagtga acaaaattta gttattaact ttatagctat gaaatttccc
     3961 cgggcatttg tttttgttca aacagacttt aacctctgca tcatacttaa ccctgcgaca
     4021 tgcgtacagt atgcatattt tgttttgaaa aaaaatgttt cgttccagtc tgttaagaat
     4081 attcaaaaat aataaaggta ttgcttaata aaattgctag aattgtttag cagtacatgc
     4141 acaatatttt actagattct ttgttttaat agtgttttgt tgagactgaa aatcttaaaa
     4201 tggtctgcgc aaatacaaaa aaaaagaaaa caccaaaaat gcaaaattct cccgtttttg
     4261 ttcctttttt aaaatttttt tttctgcaaa tgcaaataca ttcacatgtg gacagataca
     4321 tacacatagg catcatattt tagtgtatgg aaacatggtg cttttctggg gacacaagct
     4381 gaggaagtga atggctcggg ggagacacat taattgcatg gaattgttga ctgtgaaaca
     4441 cttgtagaaa tgagcacttt ggtatcccaa ccaatggtgg aatacagatt tcaatggcgc
     4501 tggggggacg agaagcagag gaattgaggc tgcaagtgat tcctgaggaa gagctcacag
     4561 ggtgatttta ttcagatgac ctctaaggga atggctagga aggagtctgt tctgaccttt
     4621 atctacctct gctgtggtaa ggccactcca tgtgccatct caccatctct tcagcgttcc
     4681 tcatgctgct tctccccgtg ccataggcgt ttccattctt gcaggaaaat gacaatgcaa
     4741 gtgcaaattc cactcacttt tattggtatg acaataaatt attctttcta aacacttagc
     4801 aaaatgacga aaagcagtat tccttaaaat ataggttttc attttctcaa tatattttga
     4861 actgactaaa gttctttaca aagacaagag gatcagaagg ttccacttac ccgtgtttta
     4921 gcgtttgttt ggagataatg ccaaccaaaa ggtggaaaac taaaaccacc attgctttac
     4981 ataagaggta cacactgccc cccacccccc aaaaaaaaac acagctttga aagttgggag
     5041 aaacactgca gtcttcattg taaatataaa gtgataattt aggtgaggaa ggaacggtaa
     5101 ggagggaagg ggaatgagtc ctttctcccc atcaagtcag ccagcattgg aatagtctct
     5161 aattctggcg gaatattttc tttgtcatgt tcatctattc ttattacagg agaatgattt
     5221 cagtgcctag tatttattag tgtaagtgtg taaccacttt cccgcaatat ttccactgga
     5281 catgttgaag caaagcagct tcttctgggg tcaggcagag gatccaaata ggcaacgact
     5341 cctttcccaa gctcagaaac aatcactgat gatgcagatt tcactacatc cgttgattct
     5401 ttgtagtagt tttcctggca cacacttgag catgcttaag gttgtgcata tgttcatttt
     5461 gaacaaataa gttcagcccc tgctcctttg taatcatcat cttgtttagt ttttcctgta
     5521 gaggatgtct accgtatact ggctaatgaa ctacaatatt aaaataatta tttctgcaag
     5581 caagttgaaa accaagaaaa caatatttgt ttcataaatg tatggcatag atttccctgt
     5641 ttattattct ttttatctgc aatagagaaa tttcagtttc tggaatatgt tggtactgct
     5701 aagctaaatg gcaaataaca tagagttcaa tgtcattctt tattgcattt acatttggtg
     5761 atacgttata ttgaactttt cttgcattaa aaagatagta tttttcccct ctctcacaag
     5821 gcagtaagtg aaagttgttc ttttaaatgg catcattaca aaaagtaatt tggtttctta
     5881 ccaataaatt ggtaccttag gtactagaac ctgtagtcat taaaacaaaa gaaaataggc
     5941 agatagcaga aacaaaagaa tgacaggaaa gaaggaagga aagaggggag tgagggaggg
     6001 agggaagaag ggagggatag agtcggggaa tgagggggaa aggaggtttc atatgaatga
     6061 ataagtacat acttttttcc gggggaaaaa aacataaatg aaataagcaa ttggatgcca
     6121 gacccatgtg ccaaatacct gaattggcat atggtatttg atatctgaac aacatcaaaa
     6181 acgttaacca gtctgaagca tgatttacat tctttctcag taacaaagac atttacaatt
     6241 ttcctgctac tcaaagcatt aaatcaacac agaactgaaa gctgcatttt gttttattta
     6301 tttagaactg cagtcaggta tttaatttct tttctgtgtg tttgtttgtt ttttgagatg
     6361 gcatcttgct ctgttgctca agctggaatg cagcggcaag atctctgctc actgcaacct
     6421 ccacttcctg ggttcaagcg attctcctgc ctcaagcctc tcgagtagct gggactacag
     6481 gcttgtgcca ccacgcctgg ctaatttgtg tatttttagt agagacgtgg tgtcgccatg
     6541 ttggccaggc tagtcttgaa ctcctgacct tgggagatcc gccgattagg cctcccaaag
     6601 tgttgggatt acaggcgtga gataccacac ccagccaggt atttaatttc ataagtgtgc
     6661 atatgcatat atgaggcgtt agggttatat actatggcat atctttagag agatataaag
     6721 atatatatac atacacacac acacacacac acacacacac acacacatcg cttgcaaata
     6781 aaacttcaac caaaacatta tgtagtccat aacagcacat gtataccata atgatgaatg
     6841 atcctacttg tttgtcaaag ttagagcagc atggtcattt aaaaaccata tctactttga
     6901 caagggaaac agactctcaa aatatctcca ttaatgaata aatcacaatt ttgaaacagg
     6961 cagaatctcc atcttccaag ctttaacaat gtttataaaa aacctaatat agcaggtagg
     7021 tattgggtga caatgaataa aaagactttc agtggggggg aaggaaaata actaagtata
     7081 gttttcaagc aatgtcttca tgacatttat aagaactatc aaacagctac aaattctaga
     7141 aattctccaa ataatgagaa aatgtataga taatcttctt agccttggaa taaaacttaa
     7201 ggcatgaaac aaaatatgaa ctatggtttt tattcttgag atactgtact tcagggctat
     7261 gtttaccaca gacaagacat tcagattaaa ctcagaagaa aatcacctgg ttattttgtc
     7321 ctgggtcaca caggtaggta atgcaaatga tggaactcaa gcatcttctg attacaaatt
     7381 acacaagctg gctccgaggc acagtgggat ccctaggtct cagacacact tgaagagttg
     7441 aatggatttt cttcatactc caagatattt gtagaatcac tcaatcttaa atgaaaaaat
     7501 caaaatgatc aggaagatct agcgaatgtc tcagagttcg tttgtcatgt tacattttgt
     7561 tccatgactt tgctgtgtta ttcaatattt tggaggtaaa ggagaagagg gtctatggga
     7621 atattttaat aaaatataga tttttaattt ttatttttaa tgtggagaaa aggcacagga
     7681 tcttagggca aagccatggt ttagggatga gctttggctc caggtgacac agggaggtca
     7741 atgatgtatt tgtacgtgac acctcatgca agaagaatac ttcgtggcaa cattggaggc
     7801 ttaaaagaga taagtaatat aaatgtgcct ggacaaaaca ggtgctcagt agtagttagt
     7861 tatcatgact attcattcac aaagtgaaac tggattggct tgctcatagg gactgctcct
     7921 ggaagttgtt cagagtttct gaatttcttt ggcttatctc ttaattacat ttttttttta
     7981 acaacacctc acatccttaa gctagcagac tgaccatcaa tagattttca atacagtttg
     8041 aaagtcttaa catatattac agaactaaag tgagctctga tgacttttaa tataaacagc
     8101 attggctatt ttcgatttcc actcccaaaa ggctactact gacaagcaaa agttaaaggc
     8161 atctacacaa attgaagtgg ttctacaagc aagtgtaaat tgatcaacag tggtagtaga
     8221 aataatgatg caacttcaaa gtggttgttt aaggcactca tagatcaaaa aatatatata
     8281 aatatttgat gcctctgaat tccttaaaaa aactatagta attttaaaca tgaaaatgtt
     8341 taaattggaa catttattat gaaaattaat taaactgaat taatatatat tttaattaac
     8401 actataatta ttatagaatg aaataacagt gaaaaagtta gaaaacctgt tcagtttttg
     8461 ataaagtata tggaaataga ttaagcaggg ctcttgagta aattatttca ttgatttgta
     8521 tctatttagg taggtgagag ttgcatagaa tcagtggcga gaaggatcag tgaaataaat
     8581 ttacaacttc agtgaagacc aggtaatgag cattgatcta tgaatacaga ctttcttcag
     8641 tgactatttc ccctaaaact cccagctcac cgcagcactg ctgcttcaag attccagtta
     8701 ttggcgtgct agccaagtag aaggtcattt ttaccgaaac gcaaatttca acttatggcc
     8761 attttctact gaccatttca ctgcaaaatg gataaaacaa taggaaatat aaactacagc
     8821 aaaagttaaa gctctatatg gacgttaaaa gaaaacctct tgctttcttt ttcttccttt
     8881 ttctcttgtt ttctttttct acctttttct gcatatggca tttattttca tatcatgata
     8941 agcattctca tgtttgcact taattttcct tatttctatt tttcttagat ttgttgatgt
     9001 tgtgtggcat attaaaagta ggaaggactg tataaactca tgtattattt ttaaattgtt
     9061 tttctgaatg tactcaagta cttttttatg tgaatatgaa cacggaataa aagtactaaa
     9121 accagttaat tatgagagac taagaatgtg gaaaggaaca ttccggagta tattagtagc
     9181 taaagaaatg ccttggatct taaatttcaa cttctaaaat tattaaaata caaatattaa
     9241 aaagatatag aggccactgc taaa
//
