LOCUS       NM_024635               5813 bp    mRNA    linear   PRI 11-FEB-2025
DEFINITION  Homo sapiens N-alpha-acetyltransferase 35, NatC auxiliary subunit
            (NAA35), transcript variant 1, mRNA.
ACCESSION   NM_024635
VERSION     NM_024635.4
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 5813)
  AUTHORS   Varland,S., Silva,R.D., Kjosas,I., Faustino,A., Bogaert,A.,
            Billmann,M., Boukhatmi,H., Kellen,B., Costanzo,M., Drazic,A.,
            Osberg,C., Chan,K., Zhang,X., Tong,A.H.Y., Andreazza,S., Lee,J.J.,
            Nedyalkova,L., Usaj,M., Whitworth,A.J., Andrews,B.J., Moffat,J.,
            Myers,C.L., Gevaert,K., Boone,C., Martinho,R.G. and Arnesen,T.
  TITLE     N-terminal acetylation shields proteins from degradation and
            promotes age-dependent motility and longevity
  JOURNAL   Nat Commun 14 (1), 6774 (2023)
   PUBMED   37891180
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5813)
  AUTHORS   Huttlin,E.L., Bruckner,R.J., Navarrete-Perea,J., Cannon,J.R.,
            Baltier,K., Gebreab,F., Gygi,M.P., Thornock,A., Zarraga,G., Tam,S.,
            Szpyt,J., Gassaway,B.M., Panov,A., Parzen,H., Fu,S., Golbazi,A.,
            Maenpaa,E., Stricker,K., Guha Thakurta,S., Zhang,T., Rad,R.,
            Pan,J., Nusinow,D.P., Paulo,J.A., Schweppe,D.K., Vaites,L.P.,
            Harper,J.W. and Gygi,S.P.
  TITLE     Dual proteome-scale networks reveal cell-specific remodeling of the
            human interactome
  JOURNAL   Cell 184 (11), 3022-3040 (2021)
   PUBMED   33961781
REFERENCE   3  (bases 1 to 5813)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   4  (bases 1 to 5813)
  AUTHORS   Lin,Y., Dong,H., Deng,W., Lin,W., Li,K., Xiong,X., Guo,Y., Zhou,F.,
            Ma,C., Chen,Y., Ren,H., Yang,H., Dai,N., Ma,L., Meltzer,S.J.,
            Yeung,S.J. and Zhang,H.
  TITLE     Evaluation of Salivary Exosomal Chimeric GOLM1-NAA35 RNA as a
            Potential Biomarker in Esophageal Carcinoma
  JOURNAL   Clin Cancer Res 25 (10), 3035-3045 (2019)
   PUBMED   30745298
  REMARK    GeneRIF: salivary exosomal GOLM1-NAA35 chimeric RNA (seG-NchiRNA)
            constitutes an effective candidate noninvasive biomarker for the
            convenient, reliable assessment of therapeutic response,
            recurrence, and early detection.
REFERENCE   5  (bases 1 to 5813)
  AUTHORS   Li,Y., Oosting,M., Deelen,P., Ricano-Ponce,I., Smeekens,S.,
            Jaeger,M., Matzaraki,V., Swertz,M.A., Xavier,R.J., Franke,L.,
            Wijmenga,C., Joosten,L.A., Kumar,V. and Netea,M.G.
  TITLE     Inter-individual variability and genetic influences on cytokine
            responses to bacteria and fungi
  JOURNAL   Nat Med 22 (8), 952-960 (2016)
   PUBMED   27376574
  REMARK    GeneRIF: A cytokine QTL at the NAA35-GOLM1 locus markedly modulated
            interleukin (IL)-6 production in response to multiple pathogens and
            was associated with susceptibility to candidemia.
            Erratum:[Nat Med. 2016 Oct 6;22(10):1192. doi:
            10.1038/nm1016-1192b.. PMID: 27711068]
REFERENCE   6  (bases 1 to 5813)
  AUTHORS   Zhang,H., Lin,W., Kannan,K., Luo,L., Li,J., Chao,P.W., Wang,Y.,
            Chen,Y.P., Gu,J. and Yen,L.
  TITLE     Aberrant chimeric RNA GOLM1-MAK10 encoding a secreted fusion
            protein as a molecular signature for human esophageal squamous cell
            carcinoma
  JOURNAL   Oncotarget 4 (11), 2135-2143 (2013)
   PUBMED   24243830
  REMARK    GeneRIF: Data demonstrate that chimera GOLM1-MAK10 encodes a
            secreted fusion protein. Mechanistic studies reveal that
            GOLM1-MAK10 is likely derived from transcription
            read-through/splicing rather than being generated from a fusion
            gene.
REFERENCE   7  (bases 1 to 5813)
  AUTHORS   Polevoda,B., Arnesen,T. and Sherman,F.
  TITLE     A synopsis of eukaryotic Nalpha-terminal acetyltransferases:
            nomenclature, subunits and substrates
  JOURNAL   BMC Proc 3 Suppl 6 (Suppl 6), S2 (2009)
   PUBMED   19660095
  REMARK    Publication Status: Online-Only
REFERENCE   8  (bases 1 to 5813)
  AUTHORS   Starheim,K.K., Gromyko,D., Evjenth,R., Ryningen,A., Varhaug,J.E.,
            Lillehaug,J.R. and Arnesen,T.
  TITLE     Knockdown of human N alpha-terminal acetyltransferase complex C
            leads to p53-dependent apoptosis and aberrant human Arl8b
            localization
  JOURNAL   Mol Cell Biol 29 (13), 3569-3581 (2009)
   PUBMED   19398576
  REMARK    GeneRIF: Human Naa35 (MAK10) is an auxiliary subunit of the human
            NatC N-terminal acetyltransferase complex. NatC acetylates
            hydrophobic Met-starting N-termini, and NatC knockdown induces
            p53-dependent apoptosis.
REFERENCE   9  (bases 1 to 5813)
  AUTHORS   Yi,X.J., Li,X.F. and Yu,F.S.
  TITLE     A novel epithelial wound-related gene is abundantly expressed in
            developing rat cornea and skin
  JOURNAL   Curr Eye Res 20 (5), 430-440 (2000)
   PUBMED   10855038
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            DB023442.1, BC117427.1, CA945233.1 and AL161447.20.
            
            On May 17, 2019 this sequence version replaced NM_024635.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1660803.48610.1,
                                           SRR1660805.148328.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1965299, SAMEA1966682
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000361671.10/ ENSP00000354972.5
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-75                DB023442.1         5-79
            76-2404             BC117427.1         1-2329
            2405-2653           CA945233.1         5-253               c
            2654-5813           AL161447.20        43540-46699
FEATURES             Location/Qualifiers
     source          1..5813
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="9"
                     /map="9q21.33"
     gene            1..5813
                     /gene="NAA35"
                     /gene_synonym="bA379P1.1; EGAP; MAK10; MAK10P"
                     /note="N-alpha-acetyltransferase 35, NatC auxiliary
                     subunit"
                     /db_xref="GeneID:60560"
                     /db_xref="HGNC:HGNC:24340"
                     /db_xref="MIM:619438"
     exon            1..128
                     /gene="NAA35"
                     /gene_synonym="bA379P1.1; EGAP; MAK10; MAK10P"
                     /inference="alignment:Splign:2.1.0"
     exon            129..257
                     /gene="NAA35"
                     /gene_synonym="bA379P1.1; EGAP; MAK10; MAK10P"
                     /inference="alignment:Splign:2.1.0"
     CDS             134..2311
                     /gene="NAA35"
                     /gene_synonym="bA379P1.1; EGAP; MAK10; MAK10P"
                     /note="corneal wound healing-related protein; protein
                     MAK10 homolog; embryonic growth-associated protein
                     homolog; MAK10 homolog, amino-acid N-acetyltransferase
                     subunit"
                     /codon_start=1
                     /product="N-alpha-acetyltransferase 35, NatC auxiliary
                     subunit"
                     /protein_id="NP_078911.3"
                     /db_xref="CCDS:CCDS6673.1"
                     /db_xref="GeneID:60560"
                     /db_xref="HGNC:HGNC:24340"
                     /db_xref="MIM:619438"
                     /translation="MVMKASVDDDDSGWELSMPEKMEKSNTNWVDITQDFEEACRELK
                     LGELLHDKLFGLFEAMSAIEMMDPKMDAGMIGNQVNRKVLNFEQAIKDGTIKIKDLTL
                     PELIGIMDTCFCCLITWLEGHSLAQTVFTCLYIHNPDFIEDPAMKAFALGILKICDIA
                     REKVNKAAVFEEEDFQSMTYGFKMANSVTDLRVTGMLKDVEDDMQRRVKSTRSRQGEE
                     RDPEVELEHQQCLAVFSRVKFTRVLLTVLIAFTKKETSAVAEAQKLMVQAADLLSAIH
                     NSLHHGIQAQNDTTKGDHPIMMGFEPLVNQRLLPPTFPRYAKIIKREEMVNYFARLID
                     RIKTVCEVVNLTNLHCILDFFCEFSEQSPCVLSRSLLQTTFLVDNKKVFGTHLMQDMV
                     KDALRSFVSPPVLSPKCYLYNNHQAKDCIDSFVTHCVRPFCSLIQIHGHNRARQRDKL
                     GHILEEFATLQDEAEKVDAALHTMLLKQEPQRQHLACLGTWVLYHNLRIMIQYLLSGF
                     ELELYSMHEYYYIYWYLSEFLYAWLMSTLSRADGSQMAEERIMEEQQKGRSSKKTKKK
                     KKVRPLSREITMSQAYQNMCAGMFKTMVAFDMDGKVRKPKFELDSEQVRYEHRFAPFN
                     SVMTPPPVHYLQFKEMSDLNKYSPPPQSPELYVAASKHFQQAKMILENIPNPDHEVNR
                     ILKVAKPNFVVMKLLAGGHKKESKVPPEFDFSAHKYFPVVKLV"
     exon            258..291
                     /gene="NAA35"
                     /gene_synonym="bA379P1.1; EGAP; MAK10; MAK10P"
                     /inference="alignment:Splign:2.1.0"
     exon            292..406
                     /gene="NAA35"
                     /gene_synonym="bA379P1.1; EGAP; MAK10; MAK10P"
                     /inference="alignment:Splign:2.1.0"
     exon            407..481
                     /gene="NAA35"
                     /gene_synonym="bA379P1.1; EGAP; MAK10; MAK10P"
                     /inference="alignment:Splign:2.1.0"
     exon            482..649
                     /gene="NAA35"
                     /gene_synonym="bA379P1.1; EGAP; MAK10; MAK10P"
                     /inference="alignment:Splign:2.1.0"
     exon            650..716
                     /gene="NAA35"
                     /gene_synonym="bA379P1.1; EGAP; MAK10; MAK10P"
                     /inference="alignment:Splign:2.1.0"
     exon            717..760
                     /gene="NAA35"
                     /gene_synonym="bA379P1.1; EGAP; MAK10; MAK10P"
                     /inference="alignment:Splign:2.1.0"
     exon            761..811
                     /gene="NAA35"
                     /gene_synonym="bA379P1.1; EGAP; MAK10; MAK10P"
                     /inference="alignment:Splign:2.1.0"
     exon            812..895
                     /gene="NAA35"
                     /gene_synonym="bA379P1.1; EGAP; MAK10; MAK10P"
                     /inference="alignment:Splign:2.1.0"
     exon            896..1010
                     /gene="NAA35"
                     /gene_synonym="bA379P1.1; EGAP; MAK10; MAK10P"
                     /inference="alignment:Splign:2.1.0"
     exon            1011..1189
                     /gene="NAA35"
                     /gene_synonym="bA379P1.1; EGAP; MAK10; MAK10P"
                     /inference="alignment:Splign:2.1.0"
     exon            1190..1249
                     /gene="NAA35"
                     /gene_synonym="bA379P1.1; EGAP; MAK10; MAK10P"
                     /inference="alignment:Splign:2.1.0"
     exon            1250..1356
                     /gene="NAA35"
                     /gene_synonym="bA379P1.1; EGAP; MAK10; MAK10P"
                     /inference="alignment:Splign:2.1.0"
     exon            1357..1423
                     /gene="NAA35"
                     /gene_synonym="bA379P1.1; EGAP; MAK10; MAK10P"
                     /inference="alignment:Splign:2.1.0"
     exon            1424..1522
                     /gene="NAA35"
                     /gene_synonym="bA379P1.1; EGAP; MAK10; MAK10P"
                     /inference="alignment:Splign:2.1.0"
     exon            1523..1701
                     /gene="NAA35"
                     /gene_synonym="bA379P1.1; EGAP; MAK10; MAK10P"
                     /inference="alignment:Splign:2.1.0"
     exon            1702..1838
                     /gene="NAA35"
                     /gene_synonym="bA379P1.1; EGAP; MAK10; MAK10P"
                     /inference="alignment:Splign:2.1.0"
     exon            1839..1906
                     /gene="NAA35"
                     /gene_synonym="bA379P1.1; EGAP; MAK10; MAK10P"
                     /inference="alignment:Splign:2.1.0"
     exon            1907..2047
                     /gene="NAA35"
                     /gene_synonym="bA379P1.1; EGAP; MAK10; MAK10P"
                     /inference="alignment:Splign:2.1.0"
     exon            2048..2170
                     /gene="NAA35"
                     /gene_synonym="bA379P1.1; EGAP; MAK10; MAK10P"
                     /inference="alignment:Splign:2.1.0"
     exon            2171..2251
                     /gene="NAA35"
                     /gene_synonym="bA379P1.1; EGAP; MAK10; MAK10P"
                     /inference="alignment:Splign:2.1.0"
     exon            2252..5813
                     /gene="NAA35"
                     /gene_synonym="bA379P1.1; EGAP; MAK10; MAK10P"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2995..3000
                     /regulatory_class="polyA_signal_sequence"
                     /gene="NAA35"
                     /gene_synonym="bA379P1.1; EGAP; MAK10; MAK10P"
                     /note="hexamer: ATTAAA"
     polyA_site      3019
                     /gene="NAA35"
                     /gene_synonym="bA379P1.1; EGAP; MAK10; MAK10P"
                     /note="major polyA site"
     regulatory      3772..3777
                     /regulatory_class="polyA_signal_sequence"
                     /gene="NAA35"
                     /gene_synonym="bA379P1.1; EGAP; MAK10; MAK10P"
                     /note="hexamer: AACAAA"
     polyA_site      3777
                     /gene="NAA35"
                     /gene_synonym="bA379P1.1; EGAP; MAK10; MAK10P"
     regulatory      3785..3790
                     /regulatory_class="polyA_signal_sequence"
                     /gene="NAA35"
                     /gene_synonym="bA379P1.1; EGAP; MAK10; MAK10P"
                     /note="hexamer: AAGAAA"
     polyA_site      3797
                     /gene="NAA35"
                     /gene_synonym="bA379P1.1; EGAP; MAK10; MAK10P"
     polyA_site      3805
                     /gene="NAA35"
                     /gene_synonym="bA379P1.1; EGAP; MAK10; MAK10P"
     regulatory      5448..5453
                     /regulatory_class="polyA_signal_sequence"
                     /gene="NAA35"
                     /gene_synonym="bA379P1.1; EGAP; MAK10; MAK10P"
                     /note="hexamer: AATAAA"
     polyA_site      5475
                     /gene="NAA35"
                     /gene_synonym="bA379P1.1; EGAP; MAK10; MAK10P"
ORIGIN      
        1 atacgcatgc gtgcacgctg ccggtcgggc tgggctgaga ggggaggggg cggcggcggc
       61 cgaggcggcg tcgttatttc cgtggtccgg acagtgcgtg gcggcgcggg tgaccacggg
      121 agaagtaggc ataatggtta tgaaagcttc tgtagatgat gacgattcag gatgggagct
      181 cagtatgcca gaaaaaatgg agaaaagcaa tacaaactgg gtggacatta cccaagattt
      241 tgaagaagct tgtcgagaat taaagttggg agaactactt catgataagc tatttggtct
      301 ttttgaagcc atgtctgcta ttgaaatgat ggatcccaag atggatgctg gcatgattgg
      361 aaaccaagtt aatcgaaaag ttctcaattt tgaacaagct atcaaggatg gcactattaa
      421 aattaaagat ctcaccttgc ctgaactgat agggattatg gatacatgtt tttgctgttt
      481 gataacgtgg ttagaaggcc attcactggc acagacagta tttacgtgcc tttacattca
      541 taatccagac tttatagaag atcctgctat gaaggctttt gctctgggaa tcttgaaaat
      601 ctgtgacatt gcaagggaaa aagtaaataa agctgctgtt tttgaagagg aagattttca
      661 gtcaatgact tatggattta aaatggctaa cagtgtgaca gatcttcgag ttacaggcat
      721 gctaaaagat gtggaggatg acatgcaaag aagagtaaag agtactcgaa gtcgacaagg
      781 agaagaaaga gatccagaag ttgaactaga acaccaacaa tgtttagcag tattcagcag
      841 agtgaaattt actcgtgtgt tactgacagt gcttatagcc tttactaaga aagagaccag
      901 tgctgttgca gaagctcaaa aattgatggt tcaagcagca gatcttcttt ctgccattca
      961 taattcattg catcatggca tccaggccca gaatgatact acaaaaggag atcatccaat
     1021 tatgatgggt tttgaacccc ttgtgaacca gaggctactt ccacctacct tccctcgata
     1081 tgcaaaaata attaaaaggg aagaaatggt gaactatttt gcaagattaa tagatagaat
     1141 aaaaactgtc tgtgaggttg tgaatttaac aaatttacat tgtatcctgg attttttctg
     1201 tgaatttagt gaacagtcac catgtgttct ttcaagatct ctgttacaaa ccactttcct
     1261 ggtggataac aaaaaggtct ttggaactca tctcatgcaa gacatggtga aagatgcact
     1321 tcggtctttt gtcagtcctc cggtgctttc ccccaagtgc tacctatata ataatcacca
     1381 ggctaaggac tgtatcgact cctttgttac tcactgtgtt cggccattct gtagtcttat
     1441 tcagatccat ggacataaca gggctcgaca gagagataag cttggtcata ttcttgagga
     1501 atttgccacc ttgcaggatg aggcagagaa ggttgatgca gcgcttcaca ccatgctgtt
     1561 gaaacaggaa ccccaaaggc aacatttggc ctgtttaggt acctgggtcc tttaccataa
     1621 ccttcgcatt atgatacagt accttctaag tggctttgaa ttggaactct acagtatgca
     1681 cgagtactat tacatatatt ggtatctctc tgaattcctt tacgcatggt tgatgtcaac
     1741 attgagtcgt gccgatggct ctcaaatggc agaggaaagg ataatggaag agcagcagaa
     1801 aggccgtagt agtaaaaaaa caaagaaaaa aaagaaagtt cgcccattga gccgagagat
     1861 cacaatgagc caagcatatc agaacatgtg tgctggaatg tttaaaacca tggtagcatt
     1921 tgacatggac ggcaaagtac gtaaaccgaa gtttgagctt gatagtgaac aagttcggta
     1981 tgaacacagg tttgctccat tcaacagtgt gatgaccccg ccgccagtgc actacttaca
     2041 gttcaaggaa atgtctgacc tcaataaata tagccctcct cctcagtctc ctgaactgta
     2101 tgtggcagct agtaagcact ttcaacaggc aaaaatgata ttggaaaata ttcctaaccc
     2161 ggaccatgag gttaatagaa ttttaaaggt tgccaaaccc aactttgtgg ttatgaagtt
     2221 attggcagga ggacacaaaa aggaatctaa agttcctcct gaatttgatt tctctgctca
     2281 taaatatttt cctgttgtga aacttgtttg agagagactg gggaggtggc cataaagggg
     2341 cagagtcttc tttcagaccc aactcttaga gggcacatca ccaggctcca catcacggga
     2401 agtgagatgg atttcttggg taacaactca ttataaggaa tacttttagt ttgacagcct
     2461 tatatgacat gaatgaaaac tgctgtttta aagtggttta ttatgttcca tggaagaaac
     2521 tggtcttatt gaatgcattg atgaacgtta tatggtttta ttacagattt aatcacaaat
     2581 cattttttat gaatgattga gtgaaaatag tgtttataaa ggttaataaa tttcttgaca
     2641 aaaaaaaaat gcactgctgg agatgaaaaa cagtaggtct ttgtccatgt taagaactga
     2701 agaaggtgta tgctctttaa catttgagta gttccaaaaa cgttatccaa aagaagtttc
     2761 aaatcaaggg attaattaaa cacttgtatg agattttggt aaaatacatt tagaagggat
     2821 ttttgggagg gcctctaaat tacatgaaaa ttgtgatttt tatgtgtcat gacatcacaa
     2881 attatatatc tgtaagaata cagatgtgta aaaaaaatcc ttttagcact tttaaaagat
     2941 tatacattgt ttgctggtga catgcaaaaa ggaggcagat agaaatgtat atagattaaa
     3001 atttaggact aggtttaaat gtggtgtact ttttgtttac ttcatattca gtttaaccca
     3061 tgaaacattt tcaaatgggt gtctgttcag tatcctctgg ctttgaaaaa ctgactacat
     3121 ccccctgtgc ttgcaagtgc ctgctgccag aggccctccc cttcctttcc tgcttgtcct
     3181 gtgtctgctc tgatgtttgc ggtggcagct ttctaggcct cttgggcctt cctttttgtc
     3241 ctctgtagca ggcaatactc ttagcaaaat gagttactct gtggtgtaaa ttggctttgg
     3301 tggcttagcc taagactagt gacagtttta tatttggtct gtggttaaaa gggttctcag
     3361 cttcaaatat cttaactctg atttggtacc tttcataaaa acatgatagt atagtgaaac
     3421 ttttctggca gtactttaaa gcagctaacc tgactgaact tgctaagggt gttcctgttg
     3481 cccctctttg cagctaatga gccctcttgg ctctcctttc caagagcggt aatacttgtg
     3541 ttattcaaga acagccatta ggtgtcctga aatttcagaa ccgaaaaatc ttaaaaaaaa
     3601 ttatttttta agtagcctgt acaatagaaa cttcaattat ggagagacaa agagtatacc
     3661 tgttactgat gtagttactt tgttgagaat gaaaactgtt tctggctggt aattactgaa
     3721 tgctttaaac aaaaaaaggc aaaggaatgg taggaaatag gcaagacaag aaacaaagaa
     3781 tcaaaagaaa aagcaaagag gaaaacagaa tgagcatgga catttggcaa acaaccaaga
     3841 agagagcctg aagcaagtta gaaagctgag aaattattat tctttcccag tggccaagat
     3901 acaaagtata aaaaatatgt cccccttaaa agcaaaaaaa ggaatgtaga ttaatgcaac
     3961 aagggccctg ctagatgatg ggatcacttt taattaagag ggtgtgctgg cattttttag
     4021 ctactatgtc tgattgggtc tgctggtata gacgagcatc taggttattt tgaagtaggt
     4081 cttcctaagt aaaagttttc ctattaaccc attatcaact aaaaaagatt gattagtgtt
     4141 agatttatca gtgtatgtta ctgacagaat catgtggttt cctttaagta gctttaattt
     4201 ttggttttta gtttgtttag agaggaggtt tcactatgtt gcccaaactg acccaaactt
     4261 gtgggctcaa gcagtcctcc tgcctcagcc cccagagtag ctgggattat aggcaaatgc
     4321 ctgcttggct agtttttgtt tttaaacagc aggtttctaa ttataaaaac aaatttgcca
     4381 ttttataatt tttaaagtaa tctgccattc aaggtactta ctgaaaaaaa caataggaga
     4441 aataagacag tctcctgtca tagagctttt atcatcttac gacaaataca gaaaagcaac
     4501 aggtattgaa aatgcagtga agaatatgct gtatgctggg taggagaact gccccacgtg
     4561 aaactttagg tgacaaatcc ccatcgcatc tattcaggag gcactgctgg gaaaagggtc
     4621 ccagacagaa tgtgcacagg cttggagggg agagggtagc agcctggccg aagtatagag
     4681 caggaaaagg atggcggaga tgagaggcaa ggagaagccg atacccaaaa ccctgggagg
     4741 ccacaggtta aagattttgg actttattct gatattggta gattctactg aaggcttgta
     4801 tgcagggaca tgatgggatc aagtcaaatc tgcttgcctg agaatggttg aaaagggagg
     4861 cagggaagcc agtcacgtga gagaaaatgt tggtcttaac aaaggtagtg gcagagcagg
     4921 tggaagaaag tggatgaaat caaatgtttt cagaggtaca gctaatggga catggtgaat
     4981 gagagtttct gccaaaatca aggatgattt ttcagaaatt tttttggctt tggcaactag
     5041 acgatggtgg tgccacttgt gtagatatct aggcaaggta ggagaccagg tttgggataa
     5101 agattgcttt agacattgag atatctttgg gacatcctgg tgaagatggc aggtagtttg
     5161 gtctcaaact gggaggtgcc atctggggtg gagatgaact gaggactcag taactatagt
     5221 cactgtaatt ttctgggggt tgccattgct cagggagctc ctagagtaag ggactgagat
     5281 aggtcccaag gaatagactt gggagggcca gggaatgggg aggccactga ggtggtggga
     5341 caggctgcag ggaagaatac ctcaaaatca tacgaggcca ctctttgaca agtgtgcctg
     5401 tttcaccgtt ttgtttgcac aagactctaa gacagtatac tgccttaaat aaagtgcacc
     5461 ctgtttggaa aagttcagga gaggtgggtg ttttccttgt tcctctttgg ctatgctctg
     5521 ggcactggaa aaagcctgca aaggagactt atcaggaaaa taagcagaat gagggccata
     5581 tgccgctcag aggccattaa gagaaggact gaaaagagcc cattgaactt ggcaagtaaa
     5641 gattgctggc gactggggcg agctctttct tgaaggggtg gggcagaagc tggaaagtca
     5701 gttgaggtgt agaccatgca gtgaggaaag agcgactcaa ctgggcttga agaactgact
     5761 tccccatatt catacttgcc ccactctatt tgtggagtgg ctggtatgat ctt
//
