LOCUS       NM_001011713            7600 bp    mRNA    linear   PRI 19-SEP-2024
DEFINITION  Homo sapiens N-alpha-acetyltransferase 30, NatC catalytic subunit
            (NAA30), mRNA.
ACCESSION   NM_001011713 XM_058661
VERSION     NM_001011713.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 7600)
  AUTHORS   Varland,S., Silva,R.D., Kjosas,I., Faustino,A., Bogaert,A.,
            Billmann,M., Boukhatmi,H., Kellen,B., Costanzo,M., Drazic,A.,
            Osberg,C., Chan,K., Zhang,X., Tong,A.H.Y., Andreazza,S., Lee,J.J.,
            Nedyalkova,L., Usaj,M., Whitworth,A.J., Andrews,B.J., Moffat,J.,
            Myers,C.L., Gevaert,K., Boone,C., Martinho,R.G. and Arnesen,T.
  TITLE     N-terminal acetylation shields proteins from degradation and
            promotes age-dependent motility and longevity
  JOURNAL   Nat Commun 14 (1), 6774 (2023)
   PUBMED   37891180
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7600)
  AUTHORS   Huttlin,E.L., Bruckner,R.J., Navarrete-Perea,J., Cannon,J.R.,
            Baltier,K., Gebreab,F., Gygi,M.P., Thornock,A., Zarraga,G., Tam,S.,
            Szpyt,J., Gassaway,B.M., Panov,A., Parzen,H., Fu,S., Golbazi,A.,
            Maenpaa,E., Stricker,K., Guha Thakurta,S., Zhang,T., Rad,R.,
            Pan,J., Nusinow,D.P., Paulo,J.A., Schweppe,D.K., Vaites,L.P.,
            Harper,J.W. and Gygi,S.P.
  TITLE     Dual proteome-scale networks reveal cell-specific remodeling of the
            human interactome
  JOURNAL   Cell 184 (11), 3022-3040 (2021)
   PUBMED   33961781
REFERENCE   3  (bases 1 to 7600)
  AUTHORS   Varland,S., Myklebust,L.M., Goksoyr,S.O., Glomnes,N., Torsvik,J.,
            Varhaug,J.E. and Arnesen,T.
  TITLE     Identification of an alternatively spliced nuclear isoform of human
            N-terminal acetyltransferase Naa30
  JOURNAL   Gene 644, 27-37 (2018)
   PUBMED   29247799
  REMARK    GeneRIF: Overexpression of full-length Naa30 increased cell
            viability.
REFERENCE   4  (bases 1 to 7600)
  AUTHORS   Starheim,K.K., Kalvik,T.V., Bjorkoy,G. and Arnesen,T.
  TITLE     Depletion of the human N-terminal acetyltransferase hNaa30 disrupts
            Golgi integrity and ARFRP1 localization
  JOURNAL   Biosci Rep 37 (2) (2017)
   PUBMED   28356483
  REMARK    GeneRIF: ARFRP1 shifted from a predominantly cis-Golgi and
            endosome-to-trans-Golgi network localization to localizing both
            Golgi and non-Golgi vesicular structures in hNaa30-depleted cells.
            Publication Status: Online-Only
REFERENCE   5  (bases 1 to 7600)
  AUTHORS   Van Damme,P., Kalvik,T.V., Starheim,K.K., Jonckheere,V.,
            Myklebust,L.M., Menschaert,G., Varhaug,J.E., Gevaert,K. and
            Arnesen,T.
  TITLE     A Role for Human N-alpha Acetyltransferase 30 (Naa30) in
            Maintaining Mitochondrial Integrity
  JOURNAL   Mol Cell Proteomics 15 (11), 3361-3372 (2016)
   PUBMED   27694331
  REMARK    GeneRIF: Data show that the human NatC complex Nt-acetylates a
            broad range of cellular proteins, and that depletion of the
            catalytic subunit Naa30 affects mitochondrial morphology and
            function.
REFERENCE   6  (bases 1 to 7600)
  AUTHORS   Mughal,A.A., Grieg,Z., Skjellegrind,H., Fayzullin,A.,
            Lamkhannat,M., Joel,M., Ahmed,M.S., Murrell,W., Vik-Mo,E.O.,
            Langmoen,I.A. and Stangeland,B.
  TITLE     Knockdown of NAT12/NAA30 reduces tumorigenic features of
            glioblastoma-initiating cells
  JOURNAL   Mol Cancer 14, 160 (2015)
   PUBMED   26292663
  REMARK    GeneRIF: NAT12/NAA30 plays an important role in growth and survival
            of GICs possibly by regulating hypoxia response (HIF1a), levels of
            p-MTOR (Ser2448) and the p53 pathway.
            Publication Status: Online-Only
REFERENCE   7  (bases 1 to 7600)
  AUTHORS   Aksnes,H., Van Damme,P., Goris,M., Starheim,K.K., Marie,M.,
            Stove,S.I., Hoel,C., Kalvik,T.V., Hole,K., Glomnes,N., Furnes,C.,
            Ljostveit,S., Ziegler,M., Niere,M., Gevaert,K. and Arnesen,T.
  TITLE     An organellar nalpha-acetyltransferase, naa60, acetylates cytosolic
            N termini of transmembrane proteins and maintains Golgi integrity
  JOURNAL   Cell Rep 10 (8), 1362-1374 (2015)
   PUBMED   25732826
REFERENCE   8  (bases 1 to 7600)
  AUTHORS   Polevoda,B., Arnesen,T. and Sherman,F.
  TITLE     A synopsis of eukaryotic Nalpha-terminal acetyltransferases:
            nomenclature, subunits and substrates
  JOURNAL   BMC Proc 3 Suppl 6 (Suppl 6), S2 (2009)
   PUBMED   19660095
  REMARK    Publication Status: Online-Only
REFERENCE   9  (bases 1 to 7600)
  AUTHORS   Starheim,K.K., Gromyko,D., Evjenth,R., Ryningen,A., Varhaug,J.E.,
            Lillehaug,J.R. and Arnesen,T.
  TITLE     Knockdown of human N alpha-terminal acetyltransferase complex C
            leads to p53-dependent apoptosis and aberrant human Arl8b
            localization
  JOURNAL   Mol Cell Biol 29 (13), 3569-3581 (2009)
   PUBMED   19398576
  REMARK    GeneRIF: Human Naa30 (MAK3) is the catalytic subunit of the human
            NatC N-terminal acetyltransferase complex. NatC acetylates
            hydrophobic Met-starting N-termini, and NatC knockdown induces
            p53-dependent apoptosis.
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK092674.1, BC118589.1, BC048983.1 and AL355834.4.
            
            On Nov 22, 2018 this sequence version replaced NM_001011713.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1660805.151325.1,
                                           SRR1660805.250676.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1968540, SAMEA1970526
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000556492.6/ ENSP00000452521.1
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-437               AK092674.1         34-470
            438-1240            BC118589.1         426-1228
            1241-1731           AK092674.1         1274-1764
            1732-1817           BC118589.1         1720-1805
            1818-2168           AK092674.1         1851-2201
            2169-4442           BC048983.1         971-3244
            4443-7600           AL355834.4         142094-145251
FEATURES             Location/Qualifiers
     source          1..7600
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="14"
                     /map="14q22.3"
     gene            1..7600
                     /gene="NAA30"
                     /gene_synonym="C14orf35; MAK3; Mak3p; NAT12; NAT12P"
                     /note="N-alpha-acetyltransferase 30, NatC catalytic
                     subunit"
                     /db_xref="GeneID:122830"
                     /db_xref="HGNC:HGNC:19844"
                     /db_xref="MIM:617989"
     exon            1..120
                     /gene="NAA30"
                     /gene_synonym="C14orf35; MAK3; Mak3p; NAT12; NAT12P"
                     /inference="alignment:Splign:2.1.0"
     exon            121..892
                     /gene="NAA30"
                     /gene_synonym="C14orf35; MAK3; Mak3p; NAT12; NAT12P"
                     /inference="alignment:Splign:2.1.0"
     CDS             122..1210
                     /gene="NAA30"
                     /gene_synonym="C14orf35; MAK3; Mak3p; NAT12; NAT12P"
                     /EC_number="2.3.1.256"
                     /note="N-acetyltransferase 12 (GCN5-related, putative);
                     N-acetyltransferase MAK3 homolog; putative
                     N-acetyltransferase; natC catalytic subunit"
                     /codon_start=1
                     /product="N-alpha-acetyltransferase 30"
                     /protein_id="NP_001011713.2"
                     /db_xref="CCDS:CCDS32088.1"
                     /db_xref="GeneID:122830"
                     /db_xref="HGNC:HGNC:19844"
                     /db_xref="MIM:617989"
                     /translation="MAEVPPGPSSLLPPPAPPAPAAVEPRCPFPAGAALACCSEDEED
                     DEEHEGGGSRSPAGGESATVAAKGHPCLRCPQPPQEQQQLNGLISPELRHLRAAASLK
                     SKVLSVAEVAATTATPDGGPRATATKGAGVHSGERPPHSLSSNARTAVPSPVEAAAAS
                     DPAAARNGLAEGTEQEEEEEDEQVRLLSSSLTADCSLRSPSGREVEPGEDRTIRYVRY
                     ESELQMPDIMRLITKDLSEPYSIYTYRYFIHNWPQLCFLAMVGEECVGAIVCKLDMHK
                     KMFRRGYIAMLAVDSKYRRNGIGTNLVKKAIYAMVEGDCDEVVLETEITNKSALKLYE
                     NLGFVRDKRLFRYYLNGVDALRLKLWLR"
     exon            893..1016
                     /gene="NAA30"
                     /gene_synonym="C14orf35; MAK3; Mak3p; NAT12; NAT12P"
                     /inference="alignment:Splign:2.1.0"
     exon            1017..1072
                     /gene="NAA30"
                     /gene_synonym="C14orf35; MAK3; Mak3p; NAT12; NAT12P"
                     /inference="alignment:Splign:2.1.0"
     exon            1073..7600
                     /gene="NAA30"
                     /gene_synonym="C14orf35; MAK3; Mak3p; NAT12; NAT12P"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1389..1394
                     /regulatory_class="polyA_signal_sequence"
                     /gene="NAA30"
                     /gene_synonym="C14orf35; MAK3; Mak3p; NAT12; NAT12P"
                     /note="hexamer: ATTAAA"
     polyA_site      1412
                     /gene="NAA30"
                     /gene_synonym="C14orf35; MAK3; Mak3p; NAT12; NAT12P"
                     /note="major polyA site"
     regulatory      2280..2285
                     /regulatory_class="polyA_signal_sequence"
                     /gene="NAA30"
                     /gene_synonym="C14orf35; MAK3; Mak3p; NAT12; NAT12P"
                     /note="hexamer: AATAAA"
     polyA_site      2302
                     /gene="NAA30"
                     /gene_synonym="C14orf35; MAK3; Mak3p; NAT12; NAT12P"
                     /note="major polyA site"
     regulatory      4421..4426
                     /regulatory_class="polyA_signal_sequence"
                     /gene="NAA30"
                     /gene_synonym="C14orf35; MAK3; Mak3p; NAT12; NAT12P"
                     /note="hexamer: AATAAA"
     polyA_site      4440
                     /gene="NAA30"
                     /gene_synonym="C14orf35; MAK3; Mak3p; NAT12; NAT12P"
                     /note="major polyA site"
     regulatory      7577..7582
                     /regulatory_class="polyA_signal_sequence"
                     /gene="NAA30"
                     /gene_synonym="C14orf35; MAK3; Mak3p; NAT12; NAT12P"
                     /note="hexamer: AATAAA"
     polyA_site      7600
                     /gene="NAA30"
                     /gene_synonym="C14orf35; MAK3; Mak3p; NAT12; NAT12P"
                     /note="major polyA site"
ORIGIN      
        1 acggcgacgg cggctgagtg agaaccttgg cggctgtgga ggctgccgcg gctgcgaagg
       61 aggcggcggc ggtggcggag gaagaggagt ggcggcagcg gcggcgggga cccgtgcggg
      121 gatggcggag gtaccgcctg ggcctagcag cctcctccca ccaccagcac ctccggcccc
      181 ggcggcggtc gagccccgct gtcccttccc ggcgggggcc gccctcgcct gctgcagcga
      241 ggacgaggag gacgacgaag agcacgaagg cggcggcagc aggagcccgg cgggcggaga
      301 gtcggcgacg gtggcggcca aggggcatcc gtgcctccgc tgccctcagc cgccgcagga
      361 gcagcagcag ctcaacggat tgattagccc cgaactgcgg cacctccggg cggccgcctc
      421 cctcaagagc aaggtcctga gcgtagcaga ggtggccgcg accacagcca cccctgacgg
      481 aggccccaga gcgactgcaa caaaaggagc cggggtacac tcgggcgaga ggccccctca
      541 ctccctctct agtaatgcaa gaactgcggt ccccagcccg gtggaggcag cggcggcgag
      601 cgatcccgcg gcggcccgca atggactggc cgagggcacc gagcaggagg aggaggagga
      661 agacgagcag gtgcggctgc tgtcttcgtc cctgaccgcc gactgcagct taagaagccc
      721 ttcgggcagg gaggttgagc ctggggagga tcggacgata cgatatgtcc gatatgaatc
      781 cgagctacaa atgcccgata tcatgagact gatcaccaaa gatctgtccg aaccctactc
      841 catttatacc tatagatatt ttatccacaa ctggccacag ctgtgcttct tggccatggt
      901 aggggaggag tgtgtaggtg ccatcgtttg caagttggat atgcacaaaa agatgttccg
      961 cagaggttat atagccatgt tagccgtgga ttccaaatac aggagaaatg gcattggtac
     1021 taacttggtt aagaaagcta tatatgccat ggttgaggga gactgtgatg aggttgtttt
     1081 ggaaaccgaa ataacaaata agtccgcttt gaaactttat gaaaatcttg gttttgttcg
     1141 agataagagg ctgttcagat actatttaaa tggagttgat gcactgcgac ttaaactgtg
     1201 gctgcgttga gaaactgaca tcaaggaaca actatcatcc gcacagaatc gacctttgca
     1261 tgcaatgcaa tttgtacaga attgctttgc aggtggattt agtaatttcc atgcagctct
     1321 tacctgtcag tgtctcattg agtgtcgcac aatatttgtt gcactttggc atggcacatt
     1381 tgttctgaat taaaagattg ttttaaactt caggagttct tttggtacca acaagatgtg
     1441 ccagttgata gccaagattt atgtgttcat ttgcaaagtc tgctgacaat gttatttaca
     1501 cagtgatcat tttatcacag aaccagtaag tggaacataa tttttgttcc ttaaaaaagc
     1561 caatgtggat tgtaaaagtc tttaagtata ctaacatttc acacaaaacc tgccctagtt
     1621 ttctgaagtg ggtgagggag acgcttcagt tttaggtttt attttttcaa tattaaattt
     1681 tccattcttg aatattggta cctcagtgat tagtgaatga aaaaaatgta gggtgggtat
     1741 gtcttacaat gagtaaaggt aacaattaaa ttttgtctgc cagtgcctgt gtagataagt
     1801 atatttgtct tcatctctag tttttgaatg catgctatct tttccttttc tttaaggcct
     1861 ttgcaagcaa acttttgttt ttatttaaat tctaaatttg ataaattatt tcagattttt
     1921 ataatttgga tacttttttc aggtgaatga aagaatggtt tactttagaa gtcccttttt
     1981 ccttacagta acaagttgaa tctacttgga aaattgagaa atggctcaaa agagataaga
     2041 aaagttgatg gagccgggaa ttgctggggt ttagatgcac tttttctttt gagagtaagg
     2101 gaagttttgg aaaagaatag aaaattagtg taagttgata tgattttatt taatcaaaat
     2161 tactgctacg ctgcgaagaa cagcttttac aaagtagctg aatttgtttt tcccacttga
     2221 tttggattca cattgctttc atttcttaaa atgcttcact tcaggttctt ggtcttggaa
     2281 ataaatttca aggtgcattg tatccatttt aagctgcttt attttatttt cacttgtatg
     2341 agcaaattct tgggggagct ttgcttttct tctgccagaa aaacaaaagg gggaaatgaa
     2401 aatctttttt ggaatgagtt ctgtgggttt tcttaacagc caccatgttt attagttaca
     2461 ttgtgttttg gccaatcagt gcaatgtaac aaattttaca gttaattgct ttcaattgag
     2521 tcagtaaacc tgtgatagat aatttattta actggaaaac ctaggtaccc ataagaaaaa
     2581 agattcattc tctgtgaaaa ctgtaggaat ctgttgttgt tttcatttga atatgctcta
     2641 cttctgctct agtatttggt ttggaatata ttttgtggct ctaattactg tatttttaaa
     2701 aaccctacct ccattaacag ttggtaaagg ccccttttca ggaaagtttg ttgctttttt
     2761 ttttttttta aaggaaagct gctctttgct cagtatagtg ttttgaaagt gaacatagta
     2821 acaaatactt taaaaataaa gatacacaat ttatatttga aaataaaaac tttctgctgg
     2881 tgggattatt tatagttctt tatttttaaa gaaaatgttt tcctttttat attgctcttg
     2941 aaagtttaat gagcagaata caatactggt tataataaaa atatggtaac cacacagtac
     3001 tcagcctttc aatatgtttt tggtcaaact tcatttaggc actagcattt agaagaatac
     3061 caatcacagt gatgcttttg ttatttaata tgaaggaaat ggaactaaaa catttatgtc
     3121 atcaaatttt atttcacttc tttatatttg acttgctggt tgatacataa tggttgatga
     3181 acatatattt gcttaaatca ctaataggga tggttgtaaa gtagatagat cattggttca
     3241 accattttag tgtttttgcc agattgtcaa tgaaaccatc atactgacct tttcctccaa
     3301 aattgccaaa ttgactgaac tggttgggtg tttgtaaaga tgacgttaac tgtgtgacta
     3361 aaaagtcaga tggttgccat attgtttgga atatgttgaa tgtcagtgta tgccttatgt
     3421 ctttaattgg gtatgcaaaa aaatttttac ttaagtagat taaaatttta acctctagca
     3481 tgaaaaccca gcaccaacac tgaaagactc cattcaggtt gaagtagcct caaacagtaa
     3541 tttacttttt gataataggc tgttgttttt cttaaataag cttaaaacaa ttctatctga
     3601 aattggtagc atgggttcac ttggctacaa ctgagcaaaa tagatgcaac tttcttttaa
     3661 tggggtgctg cctctttagg actgactgta ctatccactg acactggttt ggcagttggt
     3721 actgctgaac atttttatac atgctaccat gaagctatat atgttagtat tgaagaagct
     3781 aacgggtata ctatcatttt tgatgtgtgg gctgattata atttcctgta tttcctgtac
     3841 attgggatga aactacttta gcaaagtcca cagatcagaa accagacggt agtttttgaa
     3901 gttgaaacca gcaaaataag aaaaaataaa aaatcgattt taatattttc tgcctctttc
     3961 ccaaattacc cttcccactt gctcgacaaa tctatgtaaa gcagtttgtt ttttcatgtt
     4021 ttaactttac cttgccctgt gttatggtac tggctgacat gtctaagact ggatgtgtat
     4081 atttattatg gtgtctaaaa atcatgaagt tcatcacttt tcaggagtat agataaaatc
     4141 aaattggtag tacatcagag ttacttttca gtgcaccatg acatcactaa aatgagtgct
     4201 gtaatgttac agggctttca ggtttgtaaa aacataacca taaattatat tgacgtcaga
     4261 tatgagttga gtatctataa aatatcacgt gtatctcaaa atattggact gctgtttgac
     4321 tggatattgc tgcataattt tcttctattg tcccatatcc ttttggagag agatttaatg
     4381 ggatttgaaa tgtgcaagct gtctaaataa gatgcagtca aataaagtat ggttaagttg
     4441 tgtttgcatt tttcttttag atacagctgt gtgcatttta tgattgggtt gttttgcttt
     4501 tacctactaa gtaaaacagc aacaaacaat atattgtttc ccgcttcctg cctttcatct
     4561 aagagttacg gggaagaagt attacataat tgtcatcact gttgtgtgtt ctgacaaagt
     4621 aaatttgaaa ataacatgaa cttgattttt ctaaaagtac tcagtcaact catatgtcag
     4681 ttatcggtac attttccatg tgttcagtca aaagtttatc tttttagtct gtttcatagc
     4741 agtttatttc taagacagtt tttattttaa tttacttttt tgtctgtaca ctgccactct
     4801 gtaatgttcc ccccacccca tcccaccctt ggtaagacac caaagtaaaa tagagcaata
     4861 tccaaagagc tttttgcccc tgtcttgtga ggagctttaa atagctgtga atacttctgt
     4921 atgtcaagat tttcggattt tagtggaagg atgaaatgat ctgttttaat catttaactg
     4981 ctaaattact tttatcatgc atgccaaatc tttacattat tctttagagt aatactgtaa
     5041 aagtatctga gtttgtttta tttgggcctt atgtggaact cgaaatactt cataaattca
     5101 ctctaaggtc taaataagaa ccagaaggtt gataccattt tttcacacca gtaaacacag
     5161 atcagtatta acctgtagcc cagaggtgtt agatttattt tttgagacag agtctcactc
     5221 tgttgcccag gctggagtgc ggtggcacaa tcttggctca ctgcaacctc tgccccctgg
     5281 gttcaagcaa ttcttgtgcc ttagcctcct gagtagctgg gactacaggt gcatgccacc
     5341 acgcccagcc aatttcttgt attcttagta tgagacaggg tttcaccatg ttggccaggc
     5401 tggtctcaaa ctcctgacct caagtgatct gcccgcctcg gcctcccaaa gtgttggaat
     5461 tacaggcgtg agccaccacg cccagcctat gatattcttt ttataagcaa cttttaaaaa
     5521 gttttttaaa agatctcata agcatatagc actgctacac tttagatcac tactgtccag
     5581 tcacacttta tataaggata gatgtgtcct tttcactccc cagtatggta gttactagtc
     5641 acatgtgtag ctactgagcc cctgaagtgt gggtgggatg attgagctga atttgtaatt
     5701 ttaatcaaag ttagccacat gtggcttgtg gctactgtat tggacagcag agctttagat
     5761 aagcagtaat aacaggaagg gagtgtttgt ataggttgaa agataaaatg gaaggatcac
     5821 aattaggcca gatgtggtgg ctcacgccta ttatcccagc gttttgggag gctgagatgg
     5881 tagtttgcaa ccagccagga cagcatagca agactgtttc tgaaaaatct tttaaaataa
     5941 cacaactaaa aattacctct gagcaagagt atagctgaac tgtttatact gacaatatat
     6001 ttcattaata cagtgtttga ccactttcca ccccaccaac cactgccctt gttatgtagc
     6061 ctttctgaga aaagcagccc tttcagattt tattgttgga agttccttgg gttgcagaga
     6121 tgcagattca agtgccaaaa gttgtttctg atgagactta cctttttagc cttaaaatat
     6181 ttgtatagtt ggctctaata atttctcatt tttgatgaat ttgaaatcat ttcacttcta
     6241 aatgagattg gtcatctcat gagtggtcaa gttggaacat ggaggtctat catgttttta
     6301 acctccaaga tccacttatg gggatgaggc caaaggccaa tgttacttct agaagaacca
     6361 gattaatttt tctgccttcc atcaccgcag tgtattacct ttgaccctcg ctggtcatct
     6421 ggtaagtgta gttcatcaaa agagcagaaa taggcatagt aaacacctgg acacaaagac
     6481 agtgccaggc ttggtacaac ctgttaacac tgttgaggaa agagctcaaa acatgcatta
     6541 ctttggggat taagtcagtg tttaatctca atatgaaaca gacctagaaa taacaaagac
     6601 cactgaagtg ccaaatttat cttctaatac tactatttaa actatgcaat atgggggtta
     6661 taatgaaata gttttagtct atgtaaggtt tttataatgc taagaaataa gcttattttt
     6721 agatatggat tttttatgac tacctctttg ctgtatgaat atcttaattt tctaatacct
     6781 cagtttcatg agaactgtat gtacattttt gtaaataaaa taatttacca tatactagga
     6841 gaaggacctg cttttaaaga aattgtgtaa agacatttgt tattggatgt gttacatagt
     6901 aaatcaattt gaaatttctt aaaaacgttt ataagacttt tctggtctcc ttgaccgagg
     6961 gattttagta taagtattta gtgagatttg tattctagga agtgtgtgcc gtcacttgtt
     7021 catttacaac tgcaaagatt gtatgtctcc tatgttttcc tttcatgcca aagaaactca
     7081 ccctttttaa aagccagcag gttgcacaaa ccaaaaacaa aatattttgc cccttaaata
     7141 ggcattttaa gaagttttat ttcctggtac ttaaatattg tgtagaggga aagctagttg
     7201 taataatttg taaaaatgcg tgtattttta ggaatgcgct atttccagta agggaagtat
     7261 tgacattttt aaggaactgt gctgcattaa aatccacagt tgcatgaaac ttttaaaagt
     7321 ttaagatata aagtaattgc taaaatttgt gaactactca gaggactcaa tgccctaaca
     7381 tgtaggggat tgatcattgc gatgtttagg ccaggatttc tcatgattgt atatggttat
     7441 tgatcatttt taaggggctg aacctgctgc ctttatactt ttgacacctc cctccctccc
     7501 tccctccaaa ctgtggctgt aaacagtgac tctgcatagt cagcgttata cttgatttct
     7561 ttgtgaatgc aaataaaata aaatttgtaa gtccaccaaa
//
