LOCUS       NM_013451               6860 bp    mRNA    linear   PRI 11-DEC-2024
DEFINITION  Homo sapiens myoferlin (MYOF), transcript variant 1, mRNA.
ACCESSION   NM_013451
VERSION     NM_013451.4
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 6860)
  AUTHORS   Xiao,J., Dong,Y., Jin,J., Yuan,Z., Wang,C., Xiang,R. and Guo,Y.
  TITLE     A missense variant in MYOF is associated with ARVC and sudden
            cardiac death
  JOURNAL   Gene 902, 148193 (2024)
   PUBMED   38253296
  REMARK    GeneRIF: A missense variant in MYOF is associated with ARVC and
            sudden cardiac death.
REFERENCE   2  (bases 1 to 6860)
  AUTHORS   Anania,S., Farnir,M., Peiffer,R., Boumahd,Y., Thiry,M., Agirman,F.,
            Maloujahmoum,N., Bellahcene,A. and Peulen,O.
  TITLE     Identification of myoferlin as a mitochondria-associated membranes
            component required for calcium signaling in PDAC cell lines
  JOURNAL   Cell Commun Signal 22 (1), 133 (2024)
   PUBMED   38368370
  REMARK    GeneRIF: Identification of myoferlin as a mitochondria-associated
            membranes component required for calcium signaling in PDAC cell
            lines.
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 6860)
  AUTHORS   Fontelonga,T., Hall,A.J., Brown,J.L., Jung,Y.L., Alexander,M.S.,
            Dominov,J.A., Mouly,V., Vieira,N., Zatz,M., Vainzof,M. and
            Gussoni,E.
  TITLE     Tetraspanin CD82 Associates with Trafficking Vesicle in Muscle
            Cells and Binds to Dysferlin and Myoferlin
  JOURNAL   Adv Biol (Weinh) 7 (12), e2300157 (2023)
   PUBMED   37434585
  REMARK    GeneRIF: Tetraspanin CD82 Associates with Trafficking Vesicle in
            Muscle Cells and Binds to Dysferlin and Myoferlin.
REFERENCE   4  (bases 1 to 6860)
  AUTHORS   Polakowski,N., Sarker,M.A.K., Hoang,K., Boateng,G., Rushing,A.W.,
            Kendle,W., Pique,C., Green,P.L., Panfil,A.R. and Lemasson,I.
  TITLE     HBZ upregulates myoferlin expression to facilitate HTLV-1 infection
  JOURNAL   PLoS Pathog 19 (2), e1011202 (2023)
   PUBMED   36827461
  REMARK    GeneRIF: HBZ upregulates myoferlin expression to facilitate HTLV-1
            infection.
            Publication Status: Online-Only
REFERENCE   5  (bases 1 to 6860)
  AUTHORS   Zhang,Y., Liu,W., Yuan,W., Cai,Z., Ye,G., Zheng,G., Xu,C., Wang,X.,
            Zeng,C., Mi,R., Feng,P., Chen,F., Wu,Y., Shen,H. and Wang,P.
  TITLE     Impairment of APPL1/Myoferlin facilitates adipogenic
            differentiation of mesenchymal stem cells by blocking autophagy
            flux in osteoporosis
  JOURNAL   Cell Mol Life Sci 79 (9), 488 (2022)
   PUBMED   35984564
  REMARK    GeneRIF: Impairment of APPL1/Myoferlin facilitates adipogenic
            differentiation of mesenchymal stem cells by blocking autophagy
            flux in osteoporosis.
            Publication Status: Online-Only
REFERENCE   6  (bases 1 to 6860)
  AUTHORS   Deloukas,P., Earthrowl,M.E., Grafham,D.V., Rubenfield,M.,
            French,L., Steward,C.A., Sims,S.K., Jones,M.C., Searle,S.,
            Scott,C., Howe,K., Hunt,S.E., Andrews,T.D., Gilbert,J.G.,
            Swarbreck,D., Ashurst,J.L., Taylor,A., Battles,J., Bird,C.P.,
            Ainscough,R., Almeida,J.P., Ashwell,R.I., Ambrose,K.D.,
            Babbage,A.K., Bagguley,C.L., Bailey,J., Banerjee,R., Bates,K.,
            Beasley,H., Bray-Allen,S., Brown,A.J., Brown,J.Y., Burford,D.C.,
            Burrill,W., Burton,J., Cahill,P., Camire,D., Carter,N.P.,
            Chapman,J.C., Clark,S.Y., Clarke,G., Clee,C.M., Clegg,S., Corby,N.,
            Coulson,A., Dhami,P., Dutta,I., Dunn,M., Faulkner,L., Frankish,A.,
            Frankland,J.A., Garner,P., Garnett,J., Gribble,S., Griffiths,C.,
            Grocock,R., Gustafson,E., Hammond,S., Harley,J.L., Hart,E.,
            Heath,P.D., Ho,T.P., Hopkins,B., Horne,J., Howden,P.J., Huckle,E.,
            Hynds,C., Johnson,C., Johnson,D., Kana,A., Kay,M., Kimberley,A.M.,
            Kershaw,J.K., Kokkinaki,M., Laird,G.K., Lawlor,S., Lee,H.M.,
            Leongamornlert,D.A., Laird,G., Lloyd,C., Lloyd,D.M., Loveland,J.,
            Lovell,J., McLaren,S., McLay,K.E., McMurray,A.,
            Mashreghi-Mohammadi,M., Matthews,L., Milne,S., Nickerson,T.,
            Nguyen,M., Overton-Larty,E., Palmer,S.A., Pearce,A.V., Peck,A.I.,
            Pelan,S., Phillimore,B., Porter,K., Rice,C.M., Rogosin,A.,
            Ross,M.T., Sarafidou,T., Sehra,H.K., Shownkeen,R., Skuce,C.D.,
            Smith,M., Standring,L., Sycamore,N., Tester,J., Thorpe,A.,
            Torcasso,W., Tracey,A., Tromans,A., Tsolas,J., Wall,M., Walsh,J.,
            Wang,H., Weinstock,K., West,A.P., Willey,D.L., Whitehead,S.L.,
            Wilming,L., Wray,P.W., Young,L., Chen,Y., Lovering,R.C.,
            Moschonas,N.K., Siebert,R., Fechtel,K., Bentley,D., Durbin,R.,
            Hubbard,T., Doucette-Stamm,L., Beck,S., Smith,D.R. and Rogers,J.
  TITLE     The DNA sequence and comparative analysis of human chromosome 10
  JOURNAL   Nature 429 (6990), 375-381 (2004)
   PUBMED   15164054
REFERENCE   7  (bases 1 to 6860)
  AUTHORS   Davis,D.B., Doherty,K.R., Delmonte,A.J. and McNally,E.M.
  TITLE     Calcium-sensitive phospholipid binding properties of normal and
            mutant ferlin C2 domains
  JOURNAL   J Biol Chem 277 (25), 22883-22888 (2002)
   PUBMED   11959863
REFERENCE   8  (bases 1 to 6860)
  AUTHORS   Andersen,J.S., Lyon,C.E., Fox,A.H., Leung,A.K., Lam,Y.W., Steen,H.,
            Mann,M. and Lamond,A.I.
  TITLE     Directed proteomic analysis of the human nucleolus
  JOURNAL   Curr Biol 12 (1), 1-11 (2002)
   PUBMED   11790298
REFERENCE   9  (bases 1 to 6860)
  AUTHORS   Britton,S., Freeman,T., Vafiadaki,E., Keers,S., Harrison,R.,
            Bushby,K. and Bashir,R.
  TITLE     The third human FER-1-like protein is highly similar to dysferlin
  JOURNAL   Genomics 68 (3), 313-321 (2000)
   PUBMED   10995573
REFERENCE   10 (bases 1 to 6860)
  AUTHORS   Davis,D.B., Delmonte,A.J., Ly,C.T. and McNally,E.M.
  TITLE     Myoferlin, a candidate gene and potential modifier of muscular
            dystrophy
  JOURNAL   Hum Mol Genet 9 (2), 217-226 (2000)
   PUBMED   10607832
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from AL360229.16 and AL365364.19.
            
            On Nov 23, 2018 this sequence version replaced NM_013451.3.
            
            Summary: Mutations in dysferlin, a protein associated with the
            plasma membrane, can cause muscle weakness that affects both
            proximal and distal muscles. The protein encoded by this gene is a
            type II membrane protein that is structurally similar to dysferlin.
            It is a member of the ferlin family and associates with both plasma
            and nuclear membranes. The protein contains C2 domains that play a
            role in calcium-mediated membrane fusion events, suggesting that it
            may be involved in membrane regeneration and repair. Two transcript
            variants encoding different isoforms have been found for this gene.
            Other possible variants have been detected, but their full-length
            nature has not been determined. [provided by RefSeq, Dec 2008].
            
            Transcript Variant: This variant (1) encodes the full-length
            isoform (a).
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AF182316.1, SRR1660807.17015.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA1965299,
                                           SAMEA1966682 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000359263.9/ ENSP00000352208.4
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-228               AL360229.16        63583-63810         c
            229-284             AL360229.16        38358-38413         c
            285-376             AL360229.16        33526-33617         c
            377-485             AL360229.16        12884-12992         c
            486-573             AL360229.16        7547-7634           c
            574-740             AL365364.19        162913-163079       c
            741-869             AL365364.19        162127-162255       c
            870-932             AL365364.19        157497-157559       c
            933-983             AL365364.19        157363-157413       c
            984-1014            AL365364.19        156200-156230       c
            1015-1130           AL365364.19        155572-155687       c
            1131-1257           AL365364.19        154758-154884       c
            1258-1361           AL365364.19        152732-152835       c
            1362-1430           AL365364.19        150728-150796       c
            1431-1474           AL365364.19        150587-150630       c
            1475-1557           AL365364.19        149482-149564       c
            1558-1596           AL365364.19        146257-146295       c
            1597-1721           AL365364.19        142370-142494       c
            1722-1838           AL365364.19        141137-141253       c
            1839-2016           AL365364.19        134559-134736       c
            2017-2141           AL365364.19        133203-133327       c
            2142-2248           AL365364.19        130663-130769       c
            2249-2441           AL365364.19        128103-128295       c
            2442-2597           AL365364.19        126270-126425       c
            2598-2729           AL365364.19        122985-123116       c
            2730-2893           AL365364.19        119732-119895       c
            2894-3008           AL365364.19        117301-117415       c
            3009-3114           AL365364.19        114792-114897       c
            3115-3260           AL365364.19        113173-113318       c
            3261-3434           AL365364.19        110015-110188       c
            3435-3543           AL365364.19        108968-109076       c
            3544-3621           AL365364.19        107151-107228       c
            3622-3803           AL365364.19        105005-105186       c
            3804-3962           AL365364.19        104753-104911       c
            3963-4061           AL365364.19        104537-104635       c
            4062-4223           AL365364.19        103148-103309       c
            4224-4389           AL365364.19        100957-101122       c
            4390-4466           AL365364.19        97196-97272         c
            4467-4478           AL365364.19        93493-93504         c
            4479-4577           AL365364.19        91155-91253         c
            4578-4703           AL365364.19        89261-89386         c
            4704-4859           AL365364.19        87098-87253         c
            4860-4951           AL365364.19        86561-86652         c
            4952-5122           AL365364.19        83004-83174         c
            5123-5271           AL365364.19        82103-82251         c
            5272-5411           AL365364.19        79166-79305         c
            5412-5500           AL365364.19        76610-76698         c
            5501-5596           AL365364.19        76418-76513         c
            5597-5738           AL365364.19        73212-73353         c
            5739-5838           AL365364.19        70054-70153         c
            5839-6029           AL365364.19        66360-66550         c
            6030-6139           AL365364.19        63874-63983         c
            6140-6287           AL365364.19        63360-63507         c
            6288-6860           AL365364.19        59769-60341         c
FEATURES             Location/Qualifiers
     source          1..6860
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="10"
                     /map="10q23.33"
     gene            1..6860
                     /gene="MYOF"
                     /gene_synonym="FER1L3; HAE7"
                     /note="myoferlin"
                     /db_xref="GeneID:26509"
                     /db_xref="HGNC:HGNC:3656"
                     /db_xref="MIM:604603"
     exon            1..228
                     /gene="MYOF"
                     /gene_synonym="FER1L3; HAE7"
                     /inference="alignment:Splign:2.1.0"
     CDS             141..6326
                     /gene="MYOF"
                     /gene_synonym="FER1L3; HAE7"
                     /note="isoform a is encoded by transcript variant 1;
                     fer-1-like protein 3; fer-1-like 3, myoferlin; fer-1-like
                     family member 3"
                     /codon_start=1
                     /product="myoferlin isoform a"
                     /protein_id="NP_038479.1"
                     /db_xref="CCDS:CCDS41551.1"
                     /db_xref="GeneID:26509"
                     /db_xref="HGNC:HGNC:3656"
                     /db_xref="MIM:604603"
                     /translation="MLRVIVESASNIPKTKFGKPDPIVSVIFKDEKKKTKKVDNELNP
                     VWNEILEFDLRGIPLDFSSSLGIIVKDFETIGQNKLIGTATVALKDLTGDQSRSLPYK
                     LISLLNEKGQDTGATIDLVIGYDPPSAPHPNDLSGPSVPGMGGDGEEDEGDEDRLDNA
                     VRGPGPKGPVGTVSEAQLARRLTKVKNSRRMLSNKPQDFQIRVRVIEGRQLSGNNIRP
                     VVKVHVCGQTHRTRIKRGNNPFFDELFFYNVNMTPSELMDEIISIRVYNSHSLRADCL
                     MGEFKIDVGFVYDEPGHAVMRKWLLLNDPEDTSSGSKGYMKVSMFVLGTGDEPPPERR
                     DRDNDSDDVESNLLLPAGIALRWVTFLLKIYRAEDIPQMDDAFSQTVKEIFGGNADKK
                     NLVDPFVEVSFAGKKVCTNIIEKNANPEWNQVVNLQIKFPSVCEKIKLTIYDWDRLTK
                     NDVVGTTYLHLSKIAASGGEVEDFSSSGTGAASYTVNTGETEVGFVPTFGPCYLNLYG
                     SPREYTGFPDPYDELNTGKGEGVAYRGRILVELATFLEKTPPDKKLEPISNDDLLVVE
                     KYQRRRKYSLSAVFHSATMLQDVGEAIQFEVSIGNYGNKFDTTCKPLASTTQYSRAVF
                     DGNYYYYLPWAHTKPVVTLTSYWEDISHRLDAVNTLLAMAERLQTNIEALKSGIQGKI
                     PANQLAELWLKLIDEVIEDTRYTLPLTEGKANVTVLDTQIRKLRSRSLSQIHEAAVRM
                     RSEATDVKSTLAEIEDWLDKLMQLTEEPQNSMPDIIIWMIRGEKRLAYARIPAHQVLY
                     STSGENASGKYCGKTQTIFLKYPQEKNNGPKVPVELRVNIWLGLSAVEKKFNSFAEGT
                     FTVFAEMYENQALMFGKWGTSGLVGRHKFSDVTGKIKLKREFFLPPKGWEWEGEWIVD
                     PERSLLTEADAGHTEFTDEVYQNESRYPGGDWKPAEDTYTDANGDKAASPSELTCPPG
                     WEWEDDAWSYDINRAVDEKGWEYGITIPPDHKPKSWVAAEKMYHTHRRRRLVRKRKKD
                     LTQTASSTARAMEELQDQEGWEYASLIGWKFHWKQRSSDTFRRRRWRRKMAPSETHGA
                     AAIFKLEGALGADTTEDGDEKSLEKQKHSATTVFGANTPIVSCNFDRVYIYHLRCYVY
                     QARNLLALDKDSFSDPYAHICFLHRSKTTEIIHSTLNPTWDQTIIFDEVEIYGEPQTV
                     LQNPPKVIMELFDNDQVGKDEFLGRSIFSPVVKLNSEMDITPKLLWHPVMNGDKACGD
                     VLVTAELILRGKDGSNLPILPPQRAPNLYMVPQGIRPVVQLTAIEILAWGLRNMKNFQ
                     MASITSPSLVVECGGERVESVVIKNLKKTPNFPSSVLFMKVFLPKEELYMPPLVIKVI
                     DHRQFGRKPVVGQCTIERLDRFRCDPYAGKEDIVPQLKASLLSAPPCRDIVIEMEDTK
                     PLLASKLTEKEEEIVDWWSKFYASSGEHEKCGQYIQKGYSKLKIYNCELENVAEFEGL
                     TDFSDTFKLYRGKSDENEDPSVVGEFKGSFRIYPLPDDPSVPAPPRQFRELPDSVPQE
                     CTVRIYIVRGLELQPQDNNGLCDPYIKITLGKKVIEDRDHYIPNTLNPVFGRMYELSC
                     YLPQEKDLKISVYDYDTFTRDEKVGETIIDLENRFLSRFGSHCGIPEEYCVSGVNTWR
                     DQLRPTQLLQNVARFKGFPQPILSEDGSRIRYGGRDYSLDEFEANKILHQHLGAPEER
                     LALHILRTQGLVPEHVETRTLHSTFQPNISQGKLQMWVDVFPKSLGPPGPPFNITPRK
                     AKKYYLRVIIWNTKDVILDEKSITGEEMSDIYVKGWIPGNEENKQKTDVHYRSLDGEG
                     NFNWRFVFPFDYLPAEQLCIVAKKEHFWSIDQTEFRIPPRLIIQIWDNDKFSLDDYLG
                     FLELDLRHTIIPAKSPEKCRLDMIPDLKAMNPLKAKTASLFEQKSMKGWWPCYAEKDG
                     ARVMAGKVEMTLEILNEKEADERPAGKGRDEPNMNPKLDLPNRPETSFLWFTNPCKTM
                     KFIVWRRFKWVIIGLLFLLILLLFVAVLLYSLPNYLSMKIVKPNV"
     exon            229..284
                     /gene="MYOF"
                     /gene_synonym="FER1L3; HAE7"
                     /inference="alignment:Splign:2.1.0"
     exon            285..376
                     /gene="MYOF"
                     /gene_synonym="FER1L3; HAE7"
                     /inference="alignment:Splign:2.1.0"
     exon            377..485
                     /gene="MYOF"
                     /gene_synonym="FER1L3; HAE7"
                     /inference="alignment:Splign:2.1.0"
     exon            486..573
                     /gene="MYOF"
                     /gene_synonym="FER1L3; HAE7"
                     /inference="alignment:Splign:2.1.0"
     exon            574..740
                     /gene="MYOF"
                     /gene_synonym="FER1L3; HAE7"
                     /inference="alignment:Splign:2.1.0"
     exon            741..869
                     /gene="MYOF"
                     /gene_synonym="FER1L3; HAE7"
                     /inference="alignment:Splign:2.1.0"
     exon            870..932
                     /gene="MYOF"
                     /gene_synonym="FER1L3; HAE7"
                     /inference="alignment:Splign:2.1.0"
     exon            933..983
                     /gene="MYOF"
                     /gene_synonym="FER1L3; HAE7"
                     /inference="alignment:Splign:2.1.0"
     exon            984..1014
                     /gene="MYOF"
                     /gene_synonym="FER1L3; HAE7"
                     /inference="alignment:Splign:2.1.0"
     exon            1015..1130
                     /gene="MYOF"
                     /gene_synonym="FER1L3; HAE7"
                     /inference="alignment:Splign:2.1.0"
     exon            1131..1257
                     /gene="MYOF"
                     /gene_synonym="FER1L3; HAE7"
                     /inference="alignment:Splign:2.1.0"
     exon            1258..1361
                     /gene="MYOF"
                     /gene_synonym="FER1L3; HAE7"
                     /inference="alignment:Splign:2.1.0"
     exon            1362..1430
                     /gene="MYOF"
                     /gene_synonym="FER1L3; HAE7"
                     /inference="alignment:Splign:2.1.0"
     exon            1431..1474
                     /gene="MYOF"
                     /gene_synonym="FER1L3; HAE7"
                     /inference="alignment:Splign:2.1.0"
     exon            1475..1557
                     /gene="MYOF"
                     /gene_synonym="FER1L3; HAE7"
                     /inference="alignment:Splign:2.1.0"
     exon            1558..1596
                     /gene="MYOF"
                     /gene_synonym="FER1L3; HAE7"
                     /inference="alignment:Splign:2.1.0"
     exon            1597..1721
                     /gene="MYOF"
                     /gene_synonym="FER1L3; HAE7"
                     /inference="alignment:Splign:2.1.0"
     exon            1722..1838
                     /gene="MYOF"
                     /gene_synonym="FER1L3; HAE7"
                     /inference="alignment:Splign:2.1.0"
     exon            1839..2016
                     /gene="MYOF"
                     /gene_synonym="FER1L3; HAE7"
                     /inference="alignment:Splign:2.1.0"
     exon            2017..2141
                     /gene="MYOF"
                     /gene_synonym="FER1L3; HAE7"
                     /inference="alignment:Splign:2.1.0"
     exon            2142..2248
                     /gene="MYOF"
                     /gene_synonym="FER1L3; HAE7"
                     /inference="alignment:Splign:2.1.0"
     exon            2249..2441
                     /gene="MYOF"
                     /gene_synonym="FER1L3; HAE7"
                     /inference="alignment:Splign:2.1.0"
     exon            2442..2597
                     /gene="MYOF"
                     /gene_synonym="FER1L3; HAE7"
                     /inference="alignment:Splign:2.1.0"
     exon            2598..2729
                     /gene="MYOF"
                     /gene_synonym="FER1L3; HAE7"
                     /inference="alignment:Splign:2.1.0"
     exon            2730..2893
                     /gene="MYOF"
                     /gene_synonym="FER1L3; HAE7"
                     /inference="alignment:Splign:2.1.0"
     exon            2894..3008
                     /gene="MYOF"
                     /gene_synonym="FER1L3; HAE7"
                     /inference="alignment:Splign:2.1.0"
     exon            3009..3114
                     /gene="MYOF"
                     /gene_synonym="FER1L3; HAE7"
                     /inference="alignment:Splign:2.1.0"
     exon            3115..3260
                     /gene="MYOF"
                     /gene_synonym="FER1L3; HAE7"
                     /inference="alignment:Splign:2.1.0"
     exon            3261..3434
                     /gene="MYOF"
                     /gene_synonym="FER1L3; HAE7"
                     /inference="alignment:Splign:2.1.0"
     exon            3435..3543
                     /gene="MYOF"
                     /gene_synonym="FER1L3; HAE7"
                     /inference="alignment:Splign:2.1.0"
     exon            3544..3621
                     /gene="MYOF"
                     /gene_synonym="FER1L3; HAE7"
                     /inference="alignment:Splign:2.1.0"
     exon            3622..3803
                     /gene="MYOF"
                     /gene_synonym="FER1L3; HAE7"
                     /inference="alignment:Splign:2.1.0"
     exon            3804..3962
                     /gene="MYOF"
                     /gene_synonym="FER1L3; HAE7"
                     /inference="alignment:Splign:2.1.0"
     exon            3963..4061
                     /gene="MYOF"
                     /gene_synonym="FER1L3; HAE7"
                     /inference="alignment:Splign:2.1.0"
     exon            4062..4223
                     /gene="MYOF"
                     /gene_synonym="FER1L3; HAE7"
                     /inference="alignment:Splign:2.1.0"
     exon            4224..4389
                     /gene="MYOF"
                     /gene_synonym="FER1L3; HAE7"
                     /inference="alignment:Splign:2.1.0"
     exon            4390..4466
                     /gene="MYOF"
                     /gene_synonym="FER1L3; HAE7"
                     /inference="alignment:Splign:2.1.0"
     exon            4467..4478
                     /gene="MYOF"
                     /gene_synonym="FER1L3; HAE7"
                     /inference="alignment:Splign:2.1.0"
     exon            4479..4577
                     /gene="MYOF"
                     /gene_synonym="FER1L3; HAE7"
                     /inference="alignment:Splign:2.1.0"
     exon            4578..4703
                     /gene="MYOF"
                     /gene_synonym="FER1L3; HAE7"
                     /inference="alignment:Splign:2.1.0"
     exon            4704..4859
                     /gene="MYOF"
                     /gene_synonym="FER1L3; HAE7"
                     /inference="alignment:Splign:2.1.0"
     exon            4860..4951
                     /gene="MYOF"
                     /gene_synonym="FER1L3; HAE7"
                     /inference="alignment:Splign:2.1.0"
     exon            4952..5122
                     /gene="MYOF"
                     /gene_synonym="FER1L3; HAE7"
                     /inference="alignment:Splign:2.1.0"
     exon            5123..5271
                     /gene="MYOF"
                     /gene_synonym="FER1L3; HAE7"
                     /inference="alignment:Splign:2.1.0"
     exon            5272..5411
                     /gene="MYOF"
                     /gene_synonym="FER1L3; HAE7"
                     /inference="alignment:Splign:2.1.0"
     exon            5412..5500
                     /gene="MYOF"
                     /gene_synonym="FER1L3; HAE7"
                     /inference="alignment:Splign:2.1.0"
     exon            5501..5596
                     /gene="MYOF"
                     /gene_synonym="FER1L3; HAE7"
                     /inference="alignment:Splign:2.1.0"
     exon            5597..5738
                     /gene="MYOF"
                     /gene_synonym="FER1L3; HAE7"
                     /inference="alignment:Splign:2.1.0"
     exon            5739..5838
                     /gene="MYOF"
                     /gene_synonym="FER1L3; HAE7"
                     /inference="alignment:Splign:2.1.0"
     exon            5839..6029
                     /gene="MYOF"
                     /gene_synonym="FER1L3; HAE7"
                     /inference="alignment:Splign:2.1.0"
     exon            6030..6139
                     /gene="MYOF"
                     /gene_synonym="FER1L3; HAE7"
                     /inference="alignment:Splign:2.1.0"
     exon            6140..6287
                     /gene="MYOF"
                     /gene_synonym="FER1L3; HAE7"
                     /inference="alignment:Splign:2.1.0"
     exon            6288..6860
                     /gene="MYOF"
                     /gene_synonym="FER1L3; HAE7"
                     /inference="alignment:Splign:2.1.0"
     regulatory      6840..6845
                     /regulatory_class="polyA_signal_sequence"
                     /gene="MYOF"
                     /gene_synonym="FER1L3; HAE7"
                     /note="hexamer: AATAAA"
     polyA_site      6860
                     /gene="MYOF"
                     /gene_synonym="FER1L3; HAE7"
                     /note="major polyA site"
ORIGIN      
        1 gccttttccc cttccttgcc ctgggagaaa tcctcccttc actgggagag aacttctctc
       61 ccagggcggt gcgacccgga gctccagcgc cctagtctcc acttcgtttg ctgaaacttg
      121 ctttctacca gctaagaacc atgctgcgag tgattgtgga atctgccagc aatatcccta
      181 aaacgaaatt tggcaagccg gatcctattg tttctgtcat ttttaaggat gagaaaaaga
      241 aaacaaagaa agttgataat gaattgaacc ctgtctggaa tgagattttg gagtttgact
      301 tgaggggtat accactggac ttttcatctt cccttgggat tattgtgaaa gattttgaga
      361 caattggaca aaataaatta attggcacgg cgactgtagc cctgaaggac ctgactggtg
      421 accagagcag atccctgccg tacaagctga tctccctgct aaatgaaaaa gggcaagata
      481 ctggggccac cattgacttg gtgatcggct atgatccgcc ttctgctcca catccaaatg
      541 acctgagcgg gcccagcgtg ccaggcatgg gaggagatgg ggaagaagat gaaggtgatg
      601 aagacaggtt ggacaatgca gtcaggggcc ctgggcccaa ggggccagtt gggacggtgt
      661 cggaagctca gcttgctcgg aggctcacca aagtaaagaa cagccggcgg atgctgtcaa
      721 ataagccaca ggacttccag atccgcgtcc gagtgattga gggccgacag ttaagtggta
      781 acaacataag gcctgtggtc aaagttcacg tctgtggcca gacacaccga acaagaatca
      841 agagaggaaa caaccctttt tttgatgagt tgtttttcta caatgtcaac atgacccctt
      901 ctgaattgat ggatgagatc atcagcatcc gggtttataa ttctcactct ctgcgggcag
      961 attgtctgat gggggaattt aagattgatg ttggatttgt ttatgatgaa cctggccatg
     1021 ctgtcatgag aaagtggctt cttctcaatg acccggaaga taccagttca ggttctaaag
     1081 gttatatgaa agtcagcatg tttgtcctgg gaaccggaga tgagcctcct cctgagagac
     1141 gagatcgtga taatgacagt gatgatgtgg agagtaattt gttactccct gctggcattg
     1201 ccctccggtg ggtgaccttc ttgctgaaaa tctaccgagc tgaggacatc ccccagatgg
     1261 atgatgcctt ctcacagaca gtaaaggaaa tatttggagg caatgcagat aagaaaaatc
     1321 tcgtggatcc ttttgtagaa gtttcctttg ctggaaaaaa ggtttgtaca aacataattg
     1381 agaaaaatgc aaacccagag tggaatcagg tcgtcaatct tcagatcaag tttccttcag
     1441 tgtgtgaaaa aataaaacta acaatatatg actgggaccg tcttactaaa aatgatgtag
     1501 ttggaacaac atatctacac ctctctaaaa ttgctgcctc tggtggggaa gtggaagatt
     1561 tctcatcttc gggaactggg gctgcatcat atacagtaaa cacaggagaa acagaggtag
     1621 gctttgttcc aacgtttgga ccttgttacc tgaatcttta tggaagcccc agagagtaca
     1681 cgggattccc agacccctat gatgagctga atactggaaa gggggaagga gttgcctaca
     1741 gaggcaggat cttggttgaa ttagccactt ttcttgagaa gacaccacca gataaaaagc
     1801 ttgagcccat ttcaaatgat gacctgctgg ttgttgagaa ataccagcga aggcggaagt
     1861 acagcctgtc tgccgtgttt cattcagcca ccatgttgca agatgttggt gaggccattc
     1921 agtttgaagt cagcattggg aactatggca acaagtttga caccacctgt aagcctttgg
     1981 catcaacaac tcagtacagc cgtgctgtat ttgatggcaa ctactattat tacttgcctt
     2041 gggcccacac caagccagtt gttaccctga cttcatactg ggaggatatt agtcatcgcc
     2101 tggatgcggt gaacactctc ctagctatgg cagaacggct gcaaacaaat atagaagctc
     2161 taaaatcagg gatacaaggt aaaattcctg caaaccagct ggctgaattg tggctgaagc
     2221 tgatagatga agttatagaa gacacgagat acacgttgcc tctcacagaa ggaaaagcca
     2281 acgtcacagt tctcgatact cagatccgaa agctgcggtc caggtctctc tcccaaatac
     2341 atgaggcggc tgtgaggatg aggtcggaag ccacagatgt gaagtccaca ctggcagaaa
     2401 ttgaggactg gcttgataaa ttaatgcagc tgactgaaga gccacagaac agcatgcctg
     2461 acatcatcat ctggatgatc cggggagaga agagactggc ctatgcacga attcccgcac
     2521 atcaggtctt gtactccacc agtggtgaga atgcatctgg aaaatactgt gggaaaaccc
     2581 aaaccatctt tctgaagtat ccacaggaga aaaacaacgg gccaaaggtg cctgtggagt
     2641 tgcgagtgaa catctggcta ggcttaagtg ctgtggagaa gaagtttaac agcttcgcag
     2701 aaggaacttt caccgtcttt gctgaaatgt atgaaaatca agctctcatg tttggaaaat
     2761 ggggtacttc tggattagta ggacgtcata agttttctga tgtcacagga aaaataaaac
     2821 tcaagaggga attttttctg cctccaaaag gctgggaatg ggaaggagag tggatagttg
     2881 atcctgaaag aagcttgctg actgaggcag atgcaggtca cacggagttc actgatgaag
     2941 tctatcagaa cgagagccgc taccccgggg gcgactggaa gccggccgag gacacctaca
     3001 cggatgcgaa cggcgataaa gcagcatcac ccagcgagtt gacttgtcct ccaggttggg
     3061 aatgggaaga tgatgcatgg tcttatgaca taaatcgagc ggtggatgag aaaggctggg
     3121 aatatggaat caccattcct cctgatcata agcccaaatc ctgggttgca gcagagaaaa
     3181 tgtaccacac tcatagacgg cgaaggctgg tccgaaaacg caagaaagat ttaacacaga
     3241 ctgcttcaag caccgcaagg gccatggagg aattgcaaga ccaagagggc tgggaatatg
     3301 cttctctaat tggctggaaa tttcactgga aacaacgtag ttcagatacc ttccgccgca
     3361 gacgctggag gagaaaaatg gctccttcag aaacacatgg tgcagctgcc atctttaaac
     3421 ttgaaggtgc ccttggggca gacactaccg aagatgggga tgagaagagc ctggagaaac
     3481 agaagcacag tgccaccact gtgttcggag caaacacccc cattgtttcc tgcaattttg
     3541 acagagtcta catctaccat ctgcgctgct atgtctatca agccagaaac ctcttggctt
     3601 tagataagga tagcttttca gatccatatg ctcatatctg tttcctccat cggagcaaaa
     3661 ccactgagat catccattca accctgaatc ccacgtggga ccaaacaatt atattcgatg
     3721 aagttgaaat ctatggggaa ccccaaacag ttctacagaa tccacccaaa gttatcatgg
     3781 aactttttga caatgaccaa gtgggcaaag atgaattttt aggacgaagc attttctctc
     3841 ctgtggtgaa actgaactca gaaatggaca tcacacccaa acttctctgg cacccagtaa
     3901 tgaatggaga caaagcctgc ggggatgttc ttgtaactgc agagctgatt ctgaggggca
     3961 aggatggctc caaccttccc attcttcccc ctcaaagggc gccaaatcta tacatggtcc
     4021 cccaggggat caggcctgtg gtccagctca ctgccattga gattctagct tggggcttaa
     4081 gaaatatgaa aaacttccag atggcttcta tcacatcccc cagtcttgtt gtggagtgtg
     4141 gaggagaaag ggtggaatcg gtggtgatca aaaaccttaa gaagacaccc aactttccaa
     4201 gttctgttct cttcatgaaa gtgttcttgc ccaaggagga attgtacatg cccccactgg
     4261 tgatcaaggt catcgaccac aggcagtttg ggcggaagcc tgtcgtcggc cagtgcacca
     4321 tcgagcgcct ggaccgcttt cgctgtgacc cttatgcagg gaaagaggac atcgtcccac
     4381 agctcaaagc ctcccttctg tctgccccac catgccggga catcgttatc gaaatggaag
     4441 acaccaaacc attactggct tctaagctga cagaaaagga ggaagaaatc gtggactggt
     4501 ggagtaaatt ttatgcttcc tcaggggaac atgaaaaatg cggacagtat attcagaaag
     4561 gctattccaa gctcaagata tataattgtg aactagaaaa tgtagcagaa tttgagggcc
     4621 tgacagactt ctcagatacg ttcaagttgt accgaggcaa gtcggatgaa aatgaagatc
     4681 cttctgtggt tggagagttt aagggctcct ttcggatcta ccctctgccg gatgacccca
     4741 gcgtgccagc ccctcccaga cagtttcggg aattacctga cagcgtccca caggaatgca
     4801 cggttaggat ttacattgtt cgaggcttag agctccagcc ccaggacaac aatggcctgt
     4861 gtgaccctta cataaaaata acactgggca aaaaagtcat tgaagaccga gatcactaca
     4921 ttcccaacac tctcaaccca gtctttggca ggatgtacga actgagctgc tacttacctc
     4981 aagaaaaaga cctgaaaatt tctgtctatg attatgacac ctttacccgg gatgaaaaag
     5041 taggagaaac aattattgat ctggaaaacc gattcctttc ccgctttggg tcccactgcg
     5101 gcataccaga ggagtactgt gtttctggag tcaatacctg gcgagatcaa ctgagaccaa
     5161 cacagctgct tcaaaatgtc gccagattca aaggcttccc acaacccatc ctttccgaag
     5221 atgggagtag aatcagatat ggaggacgag actacagctt ggatgaattt gaagccaaca
     5281 aaatcctgca ccagcacctc ggggcccctg aagagcggct tgctcttcac atcctcagga
     5341 ctcaggggct ggtccctgag cacgtggaaa caaggacttt gcacagcacc ttccagccca
     5401 acatttccca gggaaaactt cagatgtggg tggatgtttt ccccaagagt ttggggccac
     5461 caggccctcc tttcaacatc acaccccgga aagccaagaa atactacctg cgtgtgatca
     5521 tctggaacac caaggacgtt atcttggacg agaaaagcat cacaggagag gaaatgagtg
     5581 acatctacgt caaaggctgg attcctggca atgaagaaaa caaacagaaa acagatgtcc
     5641 attacagatc tttggatggt gaagggaatt ttaactggcg atttgttttc ccgtttgact
     5701 accttccagc cgaacaactc tgtatcgttg cgaaaaaaga gcatttctgg agtattgacc
     5761 aaacggaatt tcgaatccca cccaggctga tcattcagat atgggacaat gacaagtttt
     5821 ctctggatga ctacttgggt ttcctagaac ttgacttgcg tcacacgatc attcctgcaa
     5881 aatcaccaga gaaatgcaga ttggacatga ttccggacct caaagccatg aaccccctta
     5941 aagccaagac agcctccctc tttgagcaga agtccatgaa aggatggtgg ccatgctacg
     6001 cagagaaaga tggcgcccgc gtaatggctg ggaaagtgga gatgacattg gaaatcctca
     6061 acgagaagga ggccgacgag aggccagccg ggaaggggcg ggacgaaccc aacatgaacc
     6121 ccaagctgga cttaccaaat cgaccagaaa cctccttcct ctggttcacc aacccatgca
     6181 agaccatgaa gttcatcgtg tggcgccgct ttaagtgggt catcatcggc ttgctgttcc
     6241 tgcttatcct gctgctcttc gtggccgtgc tcctctactc tttgccgaac tatttgtcaa
     6301 tgaagattgt aaagccaaat gtgtaacaaa ggcaaaggct tcatttcaag agtcatccag
     6361 caatgagaga atcctgcctc tgtagaccaa catccagtgt gattttgtgt ctgagaccac
     6421 accccagtag caggttacgc catgtcaccg agccccattg attcccagag ggtcttagtc
     6481 ctggaaagtc aggccaacaa gcaacgtttg catcatgtta tctcttaagt attaaaagtt
     6541 ttattttcta aagtttaaat catgtttttc aaaatatttt tcaaggtggc tggttccatt
     6601 taaaaatcat ctttttatat gtgtcttcgg ttctagactt cagcttttgg aaattgctaa
     6661 atagaattca aaaatctctg catcctgagg tgatatactt catatttgta atcaactgaa
     6721 agagctgtgc attataaaat cagttagaat agttagaaca attcttattt atgcccacaa
     6781 ccattgctat attttgtatg gatgtcataa aagtctattt aacctctgta atgaaactaa
     6841 ataaaaatgt ttcaccttta
//
