LOCUS       NM_001391940             663 bp    mRNA    linear   PRI 02-APR-2024
DEFINITION  Homo sapiens myocilin opposite strand (MYOCOS), transcript variant
            2, mRNA.
ACCESSION   NM_001391940
VERSION     NM_001391940.1
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            Z98750.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            CDS exon combination :: HY206565.1 [ECO:0000331]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000637642.2/ ENSP00000490820.1
            RefSeq Select criteria :: based on manual assertion, conservation,
                                      expression, longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-90                Z98750.1           32704-32793
            91-228              Z98750.1           34302-34439
            229-663             Z98750.1           36915-37349
FEATURES             Location/Qualifiers
     source          1..663
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="1"
                     /map="1q24.3"
     gene            1..663
                     /gene="MYOCOS"
                     /note="myocilin opposite strand"
                     /db_xref="GeneID:110806290"
                     /db_xref="HGNC:HGNC:53429"
     exon            1..90
                     /gene="MYOCOS"
                     /inference="alignment:Splign:2.1.0"
     exon            91..228
                     /gene="MYOCOS"
                     /inference="alignment:Splign:2.1.0"
     CDS             134..376
                     /gene="MYOCOS"
                     /codon_start=1
                     /product="myocilin opposite strand protein"
                     /protein_id="NP_001378869.1"
                     /db_xref="CCDS:CCDS91106.1"
                     /db_xref="GeneID:110806290"
                     /db_xref="HGNC:HGNC:53429"
                     /translation="MAQKSLANNSINLPYKDLTSEVTRRRVTMITRKEIITQKSDEAK
                     EMLSHLDLEQAPPPHRTYLTVPPAPPPSPAEDPTVS"
     exon            229..663
                     /gene="MYOCOS"
                     /inference="alignment:Splign:2.1.0"
     regulatory      646..651
                     /regulatory_class="polyA_signal_sequence"
                     /gene="MYOCOS"
                     /note="hexamer: AATAAA"
     polyA_site      663
                     /gene="MYOCOS"
                     /note="major polyA site"
ORIGIN      
        1 atgacagaaa gctcttcccc tgctctgccc ccaagaccca tcctctccct gcgacatctg
       61 tggagatttc tcaaggacac ggctccaggg gtgcagtaac tttaaattcc tcaaatcccc
      121 tgagtgcaag gccatggctc agaaaagcct tgcaaacaac agcattaatc tcccctacaa
      181 ggacttgacc tccgaggtaa ccaggcgccg agtcaccatg atcacaagaa aagagataat
      241 tacccagaaa agtgatgaag ctaaggagat gctctcccac ttggatttgg agcaagcccc
      301 tccccctcac aggacctacc tcacagtacc tcctgcccca cctccttctc cagctgagga
      361 tcccacggtc tcctaagatg taaaacttat tttgaagtga attcttacac agaactccag
      421 aaaacagttt cagtggcatt cttgaggttt gtcttagaag actcttgaag atctttgttc
      481 tttcctattt ttcttcacct agaaccacca tagagcatgg tttacccttg ctaatagact
      541 tagtcatttt tggtttttta atccaagtct ctgatatgat atgcatatat tttgatcttt
      601 atgttatgct atagaactgt tgctgtagtc agttgtattt aaattaataa acagttatca
      661 ggc
//
