LOCUS       NM_018657               4969 bp    mRNA    linear   PRI 02-APR-2024
DEFINITION  Homo sapiens myoneurin (MYNN), transcript variant 1, mRNA.
ACCESSION   NM_018657
VERSION     NM_018657.5
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 4969)
  AUTHORS   Mou,S.I., Sultana,T., Chatterjee,D., Faruk,M.O. and Hosen,M.I.
  TITLE     Comprehensive characterization of coding and non-coding single
            nucleotide polymorphisms of the Myoneurin (MYNN) gene using
            molecular dynamics simulation and docking approaches
  JOURNAL   PLoS One 19 (1), e0296361 (2024)
   PUBMED   38165846
  REMARK    GeneRIF: Comprehensive characterization of coding and non-coding
            single nucleotide polymorphisms of the Myoneurin (MYNN) gene using
            molecular dynamics simulation and docking approaches.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4969)
  AUTHORS   Haenig,C., Atias,N., Taylor,A.K., Mazza,A., Schaefer,M.H., Russ,J.,
            Riechers,S.P., Jain,S., Coughlin,M., Fontaine,J.F., Freibaum,B.D.,
            Brusendorf,L., Zenkner,M., Porras,P., Stroedicke,M., Schnoegl,S.,
            Arnsburg,K., Boeddrich,A., Pigazzini,L., Heutink,P., Taylor,J.P.,
            Kirstein,J., Andrade-Navarro,M.A., Sharan,R. and Wanker,E.E.
  TITLE     Interactome Mapping Provides a Network of Neurodegenerative Disease
            Proteins and Uncovers Widespread Protein Aggregation in Affected
            Brains
  JOURNAL   Cell Rep 32 (7), 108050 (2020)
   PUBMED   32814053
REFERENCE   3  (bases 1 to 4969)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   4  (bases 1 to 4969)
  AUTHORS   Polat,F., Yilmaz,M. and Budak Diler,S.
  TITLE     The Association of MYNN and TERC Gene Polymorphisms and Bladder
            Cancer in a Turkish Population
  JOURNAL   Urol J 16 (1), 50-55 (2019)
   PUBMED   30120764
  REMARK    GeneRIF: there may exist an association between a combination of
            MYNN rs10936599 and TERC rs2293607 polymorphisms and development of
            bladder cancer in Turkish population.
            Publication Status: Online-Only
REFERENCE   5  (bases 1 to 4969)
  AUTHORS   Speedy,H.E., Di Bernardo,M.C., Sava,G.P., Dyer,M.J., Holroyd,A.,
            Wang,Y., Sunter,N.J., Mansouri,L., Juliusson,G., Smedby,K.E.,
            Roos,G., Jayne,S., Majid,A., Dearden,C., Hall,A.G.,
            Mainou-Fowler,T., Jackson,G.H., Summerfield,G., Harris,R.J.,
            Pettitt,A.R., Allsup,D.J., Bailey,J.R., Pratt,G., Pepper,C.,
            Fegan,C., Rosenquist,R., Catovsky,D., Allan,J.M. and Houlston,R.S.
  TITLE     A genome-wide association study identifies multiple susceptibility
            loci for chronic lymphocytic leukemia
  JOURNAL   Nat Genet 46 (1), 56-60 (2014)
   PUBMED   24292274
REFERENCE   6  (bases 1 to 4969)
  AUTHORS   Guey,L.T., Garcia-Closas,M., Murta-Nascimento,C., Lloreta,J.,
            Palencia,L., Kogevinas,M., Rothman,N., Vellalta,G., Calle,M.L.,
            Marenne,G., Tardon,A., Carrato,A., Garcia-Closas,R., Serra,C.,
            Silverman,D.T., Chanock,S., Real,F.X. and Malats,N.
  CONSRTM   EPICURO/Spanish Bladder Cancer Study investigators
  TITLE     Genetic susceptibility to distinct bladder cancer subphenotypes
  JOURNAL   Eur Urol 57 (2), 283-292 (2010)
   PUBMED   19692168
  REMARK    GeneRIF: Observational study of gene-disease association. (HuGE
            Navigator)
REFERENCE   7  (bases 1 to 4969)
  AUTHORS   Hosgood,H.D. 3rd, Menashe,I., Shen,M., Yeager,M., Yuenger,J.,
            Rajaraman,P., He,X., Chatterjee,N., Caporaso,N.E., Zhu,Y.,
            Chanock,S.J., Zheng,T. and Lan,Q.
  TITLE     Pathway-based evaluation of 380 candidate genes and lung cancer
            susceptibility suggests the importance of the cell cycle pathway
  JOURNAL   Carcinogenesis 29 (10), 1938-1943 (2008)
   PUBMED   18676680
  REMARK    GeneRIF: Observational study of gene-disease association. (HuGE
            Navigator)
REFERENCE   8  (bases 1 to 4969)
  AUTHORS   Nanjundan,M., Nakayama,Y., Cheng,K.W., Lahad,J., Liu,J., Lu,K.,
            Kuo,W.L., Smith-McCune,K., Fishman,D., Gray,J.W. and Mills,G.B.
  TITLE     Amplification of MDS1/EVI1 and EVI1, located in the 3q26.2
            amplicon, is associated with favorable patient prognosis in ovarian
            cancer
  JOURNAL   Cancer Res 67 (7), 3074-3084 (2007)
   PUBMED   17409414
REFERENCE   9  (bases 1 to 4969)
  AUTHORS   Cifuentes-Diaz,C., Bitoun,M., Goudou,D., Seddiqi,N., Romero,N.,
            Rieger,F., Perin,J.P. and Alliel,P.M.
  TITLE     Neuromuscular expression of the BTB/POZ and zinc finger protein
            myoneurin
  JOURNAL   Muscle Nerve 29 (1), 59-65 (2004)
   PUBMED   14694499
REFERENCE   10 (bases 1 to 4969)
  AUTHORS   Alliel,P.M., Seddiqi,N., Goudou,D., Cifuentes-Diaz,C., Romero,N.,
            Velasco,E., Rieger,F. and Perin,J.P.
  TITLE     Myoneurin, a novel member of the BTB/POZ-zinc finger family highly
            expressed in human muscle
  JOURNAL   Biochem Biophys Res Commun 273 (1), 385-391 (2000)
   PUBMED   10873615
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from BX648128.1, AC078795.19 and
            DB134736.1.
            
            On Jun 2, 2019 this sequence version replaced NM_018657.4.
            
            Summary: This gene encodes a member of the BTB/POZ and zinc finger
            domain-containing protein family that are involved in the control
            of gene expression. Alternative splicing results in multiple
            transcript variants and a pseudogene has been identified on
            chromosome 14. [provided by RefSeq, Jun 2010].
            
            Transcript Variant: This variant (1) encodes the longer isoform
            (A). Both variants 1 and 2 encode the same protein (isoform A).
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1803612.35341.1,
                                           SRR1660803.96190.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1965299, SAMEA1966682
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000349841.10/ ENSP00000326240.4
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1288              BX648128.1         332-1619
            1289-1289           AC078795.19        119832-119832       c
            1290-2803           BX648128.1         1621-3134
            2804-4404           AC078795.19        111401-113001       c
            4405-4969           DB134736.1         1-565
FEATURES             Location/Qualifiers
     source          1..4969
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="3"
                     /map="3q26.2"
     gene            1..4969
                     /gene="MYNN"
                     /gene_synonym="OSZF; SBBIZ1; ZBTB31; ZNF902"
                     /note="myoneurin"
                     /db_xref="GeneID:55892"
                     /db_xref="HGNC:HGNC:14955"
                     /db_xref="MIM:606042"
     exon            1..67
                     /gene="MYNN"
                     /gene_synonym="OSZF; SBBIZ1; ZBTB31; ZNF902"
                     /inference="alignment:Splign:2.1.0"
     exon            68..364
                     /gene="MYNN"
                     /gene_synonym="OSZF; SBBIZ1; ZBTB31; ZNF902"
                     /inference="alignment:Splign:2.1.0"
     CDS             99..1931
                     /gene="MYNN"
                     /gene_synonym="OSZF; SBBIZ1; ZBTB31; ZNF902"
                     /note="isoform A is encoded by transcript variant 1; zinc
                     finger protein with BTB/POZ domain; zinc finger and BTB
                     domain-containing protein 31"
                     /codon_start=1
                     /product="myoneurin isoform A"
                     /protein_id="NP_061127.1"
                     /db_xref="CCDS:CCDS3207.1"
                     /db_xref="GeneID:55892"
                     /db_xref="HGNC:HGNC:14955"
                     /db_xref="MIM:606042"
                     /translation="MQYSHHCEHLLERLNKQREAGFLCDCTIVIGEFQFKAHRNVLAS
                     FSEYFGAIYRSTSENNVFLDQSQVKADGFQKLLEFIYTGTLNLDSWNVKEIHQAADYL
                     KVEEVVTKCKIKMEDFAFIANPSSTEISSITGNIELNQQTCLLTLRDYNNREKSEVST
                     DLIQANPKQGALAKKSSQTKKKKKAFNSPKTGQNKTVQYPSDILENASVELFLDANKL
                     PTPVVEQVAQINDNSELELTSVVENTFPAQDIVHTVTVKRKRGKSQPNCALKEHSMSN
                     IASVKSPYEAENSGEELDQRYSKAKPMCNTCGKVFSEASSLRRHMRIHKGVKPYVCHL
                     CGKAFTQCNQLKTHVRTHTGEKPYKCELCDKGFAQKCQLVFHSRMHHGEEKPYKCDVC
                     NLQFATSSNLKIHARKHSGEKPYVCDRCGQRFAQASTLTYHVRRHTGEKPYVCDTCGK
                     AFAVSSSLITHSRKHTGEKPYICGICGKSFISSGELNKHFRSHTGERPFICELCGNSY
                     TDIKNLKKHKTKVHSGADKTLDSSAEDHTLSEQDSIQKSPLSETMDVKPSDMTLPLAL
                     PLGTEDHHMLLPVTDTQSPTSDTLLRSTVNGYSEPQLIFLQQLY"
     exon            365..1158
                     /gene="MYNN"
                     /gene_synonym="OSZF; SBBIZ1; ZBTB31; ZNF902"
                     /inference="alignment:Splign:2.1.0"
     exon            1159..1318
                     /gene="MYNN"
                     /gene_synonym="OSZF; SBBIZ1; ZBTB31; ZNF902"
                     /inference="alignment:Splign:2.1.0"
     exon            1319..1497
                     /gene="MYNN"
                     /gene_synonym="OSZF; SBBIZ1; ZBTB31; ZNF902"
                     /inference="alignment:Splign:2.1.0"
     exon            1498..1581
                     /gene="MYNN"
                     /gene_synonym="OSZF; SBBIZ1; ZBTB31; ZNF902"
                     /inference="alignment:Splign:2.1.0"
     exon            1582..1668
                     /gene="MYNN"
                     /gene_synonym="OSZF; SBBIZ1; ZBTB31; ZNF902"
                     /inference="alignment:Splign:2.1.0"
     exon            1669..4969
                     /gene="MYNN"
                     /gene_synonym="OSZF; SBBIZ1; ZBTB31; ZNF902"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2052..2057
                     /regulatory_class="polyA_signal_sequence"
                     /gene="MYNN"
                     /gene_synonym="OSZF; SBBIZ1; ZBTB31; ZNF902"
                     /note="hexamer: AGTAAA"
     polyA_site      2079
                     /gene="MYNN"
                     /gene_synonym="OSZF; SBBIZ1; ZBTB31; ZNF902"
                     /note="major polyA site"
     regulatory      2393..2398
                     /regulatory_class="polyA_signal_sequence"
                     /gene="MYNN"
                     /gene_synonym="OSZF; SBBIZ1; ZBTB31; ZNF902"
                     /note="hexamer: AATAAA"
     polyA_site      2422
                     /gene="MYNN"
                     /gene_synonym="OSZF; SBBIZ1; ZBTB31; ZNF902"
     regulatory      2782..2787
                     /regulatory_class="polyA_signal_sequence"
                     /gene="MYNN"
                     /gene_synonym="OSZF; SBBIZ1; ZBTB31; ZNF902"
                     /note="hexamer: AATAAA"
     polyA_site      2806
                     /gene="MYNN"
                     /gene_synonym="OSZF; SBBIZ1; ZBTB31; ZNF902"
     regulatory      3717..3722
                     /regulatory_class="polyA_signal_sequence"
                     /gene="MYNN"
                     /gene_synonym="OSZF; SBBIZ1; ZBTB31; ZNF902"
                     /note="hexamer: ATTAAA"
     polyA_site      3753
                     /gene="MYNN"
                     /gene_synonym="OSZF; SBBIZ1; ZBTB31; ZNF902"
     regulatory      4318..4323
                     /regulatory_class="polyA_signal_sequence"
                     /gene="MYNN"
                     /gene_synonym="OSZF; SBBIZ1; ZBTB31; ZNF902"
                     /note="hexamer: AATAAA"
     polyA_site      4340
                     /gene="MYNN"
                     /gene_synonym="OSZF; SBBIZ1; ZBTB31; ZNF902"
     regulatory      4405..4410
                     /regulatory_class="polyA_signal_sequence"
                     /gene="MYNN"
                     /gene_synonym="OSZF; SBBIZ1; ZBTB31; ZNF902"
                     /note="hexamer: TATAAA"
     polyA_site      4431
                     /gene="MYNN"
                     /gene_synonym="OSZF; SBBIZ1; ZBTB31; ZNF902"
ORIGIN      
        1 ggtgacgtcc tcccaagatg gcggagacag agtgaagaaa ctgtgttccc cccttgggtt
       61 gctatcgatc aagggtaaaa ttccattctg atatcaaaat gcagtattcg caccactgtg
      121 agcacctttt agagagactg aacaaacagc gggaagcagg ttttctctgt gactgtacca
      181 tagtgattgg ggaattccag tttaaagctc ataggaatgt gctggcctcc tttagtgagt
      241 attttggtgc gatctacaga agcacttctg agaacaatgt ctttcttgat cagagtcagg
      301 tgaaggctga tggatttcag aaactgttgg agtttatata cacaggaact ttaaatcttg
      361 acagttggaa tgttaaagaa attcatcagg ctgctgacta tctcaaagtg gaagaggtgg
      421 tcactaaatg caaaataaag atggaagatt ttgcttttat tgctaatcct tcttctacag
      481 agatatctag tattactgga aacattgaat tgaatcaaca gacttgtctt cttactctgc
      541 gagattataa taatcgagag aaatcagaag tatctacaga tttgattcag gcaaatccta
      601 aacaaggcgc gttagcgaaa aagtcatctc aaacgaaaaa gaagaagaag gctttcaact
      661 ccccgaaaac agggcagaat aaaacagtgc aatatcccag tgacatctta gagaatgcat
      721 ctgttgaatt attcctagat gcaaataaac tgcccacacc tgtagtagaa caagttgcac
      781 aaataaatga taattcagaa ctcgagttga catcagttgt ggaaaatact tttccagcac
      841 aagatattgt gcacactgtt acagtgaaac ggaaacgtgg aaaatcacag ccaaactgtg
      901 ctctgaaaga acactctatg tctaatatag ccagcgtcaa gagtccttat gaggcggaga
      961 actccgggga agagctggat cagaggtatt ccaaggccaa gccaatgtgt aacacatgtg
     1021 ggaaagtgtt ttcagaagcc agcagtttga gaaggcacat gagaatacat aaaggagtca
     1081 aaccttacgt ctgccactta tgtggaaagg catttaccca atgtaaccag ctgaaaacgc
     1141 atgtaagaac tcatacaggt gagaagccat acaaatgtga attgtgtgat aaaggatttg
     1201 ctcagaaatg tcagctagtc ttccatagtc gcatgcatca tggtgaagaa aaaccctata
     1261 aatgtgatgt atgcaactta cagtttgcaa cttctagcaa tctcaagatt catgcaagga
     1321 agcatagtgg agagaagcca tatgtctgtg ataggtgtgg acagagattt gctcaagcca
     1381 gcacactgac ctatcatgtc cgtaggcata ctggagaaaa gccttatgta tgtgatacct
     1441 gtgggaaggc atttgctgtc tctagttctc ttatcactca ttctcgaaaa catacaggtg
     1501 aaaaaccata catatgtggt atttgtggga aaagttttat ttcctcagga gagctcaaca
     1561 aacactttcg gtcccataca ggagaaagac catttatctg cgaattatgt ggaaattctt
     1621 acacagatat taaaaattta aagaagcaca aaacaaaagt ccattctggt gcagataaaa
     1681 ctctagactc cagtgcagag gatcatactt tgagtgaaca ggattccata caaaaaagtc
     1741 ctttatcaga aactatggat gtgaagcctt ctgatatgac tttaccatta gctcttccac
     1801 ttgggactga ggaccatcac atgcttctgc ctgtcacgga tactcagtct cctacatcag
     1861 atacattgtt gaggtcaact gtgaatgggt attcagaacc acagttgatt tttttacaac
     1921 aattatactg actttgtaag gaatatggaa ttgctaagat atcattggta gcaaacatct
     1981 ctggtaaggt gcatatattc atattaaatt cccattcatt tgagttgtga ccattatttt
     2041 tcattcactg aagtaaaagc acctgatgct gcatcacaac tgcaatgttt gtttttattt
     2101 ttggctttat gtctatactc cacagagagc tttttaagta atgaattatg tagcactatt
     2161 ttgggtggat gagttttatt ttcttttaaa gctgccttaa ttccattttt attttgcatt
     2221 ttagaattgc ccttcattta ctaaatcagc cagttaatgt gattcagttg tgacctgtgg
     2281 gattttaaaa ttttcctgcc ctcataattt aagcaaaatc cacgatagta tcagcccaag
     2341 agtgtgttgc tatttgtaag ccccatggat caatacataa actatgcata aaaataaaat
     2401 ttcatatttt cgctcgtaaa aatttaggcg ctgaataaga attgtgctat ttctctatta
     2461 atatattgtt agaaataact tttctaatga aacaaaaatg tttctcaaaa tctagaaaag
     2521 tgcatataaa tttttgttca tttagaactg agtattctgg agaaaaccaa tggtcagcac
     2581 ttttggtttg agttatctga gattgtattt tcaaaatgaa ttttaagtag atatttggtg
     2641 tttttatctt gtcaaagaca gtttcaaaat ttgattcagt ttatgtttta ttccgttcta
     2701 aaatattgga gatgaggaaa atgtacttga gttttgaaat attttggtaa gcctctctta
     2761 ctcctgttat gcacttttta aaataaatac tgaattccag aaagaatttt ctagatataa
     2821 acttaatgca tactagaaat cacttggctt ctaaatttgg tacattatat tgcataaaga
     2881 gttaagaaat taacctcaat tataagtaaa cattttgagt taccagaaag ccaactatag
     2941 ttaaatattt tatatctgag ttttctataa gtttggggtt tgttaatttt ataaattaaa
     3001 ccacaacttt tggtggtggt tgtagtttca caatggtcct tttccttcca aatgaatgta
     3061 gaaaattcgt tattatcctg atatttgcac cactcatccc catgccactt ttcccacata
     3121 ttaatttatt tcactgcctg atctttggat atgaaattat gagttccaca aagtcaattt
     3181 ttatagtgcc aatcaaacag catggtgata ttctttttct ttttttttcc ccccacaagg
     3241 ctgttgttca gtgtgagatg acatcatttc ttatttctgc catgctgtgg cttttttgtg
     3301 ttctgctttt aaactacacc tgtagtacag ttaatatgtt ttttattggt attgatttct
     3361 ttaattcatt aattttctct atttgggacc caagtcataa gaaccaatta gaggacataa
     3421 taaaaacact taatgcttgt agtctgtaga gatcttcacc atttcacagc acacacatta
     3481 ttttcataat aaattgccac tggtgggaca tgggactgac ttatttgaat agagtttgaa
     3541 ataccacctt tgtatgatgc aaacaatatt tgattatttt atctaagaaa tctatgcatg
     3601 tgtatcaagt taaaatagtg ggtttaaata caatttacaa agcattagaa tgttacctaa
     3661 tctcttctgg gttaaatgtg ataggaatgt attggaatgt gaagaaatta tagaaaatta
     3721 aaagactcag cctctttagg aagtttgcta aaatggagag gttatgttta atttatttat
     3781 atcttcgtta atccaagcat ctaatgaaca aaaaactgct acagtgacgt cataattcta
     3841 taagggcaat agttgccaaa tttcctctgg tattattagc attctgcctt tgcatagatt
     3901 agccttcaaa tttattattt ttagtattat ttgatacgat tgaagtggct aagattgatt
     3961 gagcttttct tgatcacatt ttctgcttct tagctaaagt aattttattt aaattgacat
     4021 ggcttgagtt gtcatcattt tctgctcttc tagaatgatg tgtagagaaa acttgaagat
     4081 actatccctt ctttggcatt cttctcttaa tgctatgcta ttatttatca taatatgcat
     4141 atatttagtt gtatctggta tcattctaac actcataact accattttag ttaagtccaa
     4201 ctttatattt gttacaatgc agtgttttgg gaaaggtcta ttagtaatta tttaagtatt
     4261 acatattttt atggaagtct ttagaaggtg aagatcttac tgagaaacta ttttctaaat
     4321 aaatttaatt ttcttttgta tttgtatcag atcatgccta ctgtatgtta gattttagac
     4381 tattttaaaa gaaaccgtag attatataaa aatttttttg ctgtttttaa atggcatttg
     4441 tcttatgttt aatttcacag gatgattttg atagacaaat tttagaaaac cttttttcaa
     4501 aggtaatggt tctatcagtt tcattccaac agtagctaat ttctgtgttt cagtcctaca
     4561 gaaattgtgt gagtagttga aataatgtac atgtactagt ttttttaagt attctaaata
     4621 gttctaacat ttaatgcata tcagaaacat gcttaagaaa taacaatatc caggcccacc
     4681 ccacctattg aatcagacag ttcccagggc atatatatgc tggggaagcc ccataggtga
     4741 ttttaatgta taccaaacat gtagagtctc actctgttgc ccaggctgga gtgcaatgac
     4801 gtgatctcag ctaactgcaa cctctgcctc ctggattcaa gcaattctcc ggcctcagcc
     4861 tcctgagtag ctggtactac aggtgcgcgc caccacacct gactaatttt tgttagagat
     4921 ggggtttcat tctgttggcc aggctggtct cgaactcctg acctcaggt
//
