LOCUS       NM_002457              15574 bp    mRNA    linear   PRI 01-OCT-2024
DEFINITION  Homo sapiens mucin 2, oligomeric mucus/gel-forming (MUC2), mRNA.
ACCESSION   NM_002457 XM_370601
VERSION     NM_002457.5
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 15574)
  AUTHORS   Zhu,X., Li,Y., Tian,X., Jing,Y., Wang,Z., Yue,L., Li,J., Wu,L.,
            Zhou,X., Yu,Z., Zhang,Y., Guan,F., Yang,M. and Zhang,B.
  TITLE     REGgamma Mitigates Radiation-Induced Enteritis by Preserving Mucin
            Secretion and Sustaining Microbiome Homeostasis
  JOURNAL   Am J Pathol 194 (6), 975-988 (2024)
   PUBMED   38423356
  REMARK    GeneRIF: REGgamma Mitigates Radiation-Induced Enteritis by
            Preserving Mucin Secretion and Sustaining Microbiome Homeostasis.
REFERENCE   2  (bases 1 to 15574)
  AUTHORS   Recktenwald,C.V., Karlsson,G., Garcia-Bonete,M.J., Katona,G.,
            Jensen,M., Lymer,R., Backstrom,M., Johansson,M.E.V., Hansson,G.C.
            and Trillo-Muyo,S.
  TITLE     The structure of the second CysD domain of MUC2 and role in mucin
            organization by transglutaminase-based cross-linking
  JOURNAL   Cell Rep 43 (5), 114207 (2024)
   PUBMED   38733585
  REMARK    GeneRIF: The structure of the second CysD domain of MUC2 and role
            in mucin organization by transglutaminase-based cross-linking.
REFERENCE   3  (bases 1 to 15574)
  AUTHORS   Monno,M., Ogiri,M., Seishima,R., Suzuki,Y., Hattori,K., Matsui,S.,
            Shigeta,K., Okabayashi,K. and Kitagawa,Y.
  TITLE     POFUT1 and PLAGL2 are characteristic markers of mucinous colorectal
            cancer associated with MUC2 expression
  JOURNAL   Cell Biochem Funct 42 (2), e3989 (2024)
   PUBMED   38500386
  REMARK    GeneRIF: POFUT1 and PLAGL2 are characteristic markers of mucinous
            colorectal cancer associated with MUC2 expression.
REFERENCE   4  (bases 1 to 15574)
  AUTHORS   Saha,A., Gavert,N., Brabletz,T. and Ben-Ze'ev,A.
  TITLE     An Increase in Mucin2 Expression Is Required for Colon Cancer
            Progression Mediated by L1
  JOURNAL   Int J Mol Sci 24 (17), 13418 (2023)
   PUBMED   37686224
  REMARK    GeneRIF: An Increase in Mucin2 Expression Is Required for Colon
            Cancer Progression Mediated by L1.
            Publication Status: Online-Only
REFERENCE   5  (bases 1 to 15574)
  AUTHORS   Moehle,C., Ackermann,N., Langmann,T., Aslanidis,C., Kel,A.,
            Kel-Margoulis,O., Schmitz-Madry,A., Zahn,A., Stremmel,W. and
            Schmitz,G.
  TITLE     Aberrant intestinal expression and allelic variants of mucin genes
            associated with inflammatory bowel disease
  JOURNAL   J Mol Med (Berl) 84 (12), 1055-1066 (2006)
   PUBMED   17058067
  REMARK    GeneRIF: Aberrant intestinal expression and allelic variant MUC2 is
            associated with inflammatory bowel disease.
REFERENCE   6  (bases 1 to 15574)
  AUTHORS   Gum,J.R. Jr., Hicks,J.W., Toribara,N.W., Rothe,E.M., Lagace,R.E.
            and Kim,Y.S.
  TITLE     The human MUC2 intestinal mucin has cysteine-rich subdomains
            located both upstream and downstream of its central repetitive
            region
  JOURNAL   J Biol Chem 267 (30), 21375-21383 (1992)
   PUBMED   1400449
REFERENCE   7  (bases 1 to 15574)
  AUTHORS   Xu,G., Huan,L., Khatri,I., Sajjan,U.S., McCool,D., Wang,D.,
            Jones,C., Forstner,G. and Forstner,J.
  TITLE     Human intestinal mucin-like protein (MLP) is homologous with rat
            MLP in the C-terminal region, and is encoded by a gene on
            chromosome 11 p 15.5
  JOURNAL   Biochem Biophys Res Commun 183 (2), 821-828 (1992)
   PUBMED   1550588
REFERENCE   8  (bases 1 to 15574)
  AUTHORS   Toribara,N.W., Gum,J.R. Jr., Culhane,P.J., Lagace,R.E., Hicks,J.W.,
            Petersen,G.M. and Kim,Y.S.
  TITLE     MUC-2 human small intestinal mucin gene structure. Repeated arrays
            and polymorphism
  JOURNAL   J Clin Invest 88 (3), 1005-1013 (1991)
   PUBMED   1885763
REFERENCE   9  (bases 1 to 15574)
  AUTHORS   Jany,B.H., Gallup,M.W., Yan,P.S., Gum,J.R., Kim,Y.S. and
            Basbaum,C.B.
  TITLE     Human bronchus and intestine express the same mucin gene
  JOURNAL   J Clin Invest 87 (1), 77-82 (1991)
   PUBMED   1985113
REFERENCE   10 (bases 1 to 15574)
  AUTHORS   Griffiths,B., Matthews,D.J., West,L., Attwood,J., Povey,S.,
            Swallow,D.M., Gum,J.R. and Kim,Y.S.
  TITLE     Assignment of the polymorphic intestinal mucin gene (MUC2) to
            chromosome 11p15
  JOURNAL   Ann Hum Genet 54 (4), 277-285 (1990)
   PUBMED   1980995
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from MH593786.1.
            
            On Feb 28, 2023 this sequence version replaced NM_002457.4.
            
            Summary: This gene encodes a member of the mucin protein family.
            Mucins are high molecular weight glycoproteins produced by many
            epithelial tissues. The protein encoded by this gene is secreted
            and forms an insoluble mucous barrier that protects the gut lumen.
            The protein polymerizes into a gel of which 80% is composed of
            oligosaccharide side chains by weight. The protein features a
            central domain containing tandem repeats rich in threonine and
            proline that varies between 50 and 115 copies in different
            individuals. Downregulation of this gene has been observed in
            patients with Crohn disease and ulcerative colitis. [provided by
            RefSeq, Oct 2016].
            
            Sequence Note: This gene contains a variable number of tandem
            repeats, estimated to vary between 50-115 repeat units in the human
            genome.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            RNAseq introns :: partial sample support SAMEA1968540, SAMEA2142348
                              [ECO:0000350]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000713550.1/ ENSP00000518846.1
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-104               MH593786.1         71614-71717
            105-375             MH593786.1         72391-72661
            376-490             MH593786.1         74338-74452
            491-581             MH593786.1         74836-74926
            582-691             MH593786.1         75007-75116
            692-902             MH593786.1         75196-75406
            903-1028            MH593786.1         76398-76523
            1029-1146           MH593786.1         77021-77138
            1147-1285           MH593786.1         77217-77355
            1286-1396           MH593786.1         77614-77724
            1397-1466           MH593786.1         77813-77882
            1467-1604           MH593786.1         78161-78298
            1605-1769           MH593786.1         78389-78553
            1770-1864           MH593786.1         79027-79121
            1865-1991           MH593786.1         79328-79454
            1992-2247           MH593786.1         79804-80059
            2248-2300           MH593786.1         80290-80342
            2301-2401           MH593786.1         80481-80581
            2402-2553           MH593786.1         80982-81133
            2554-2692           MH593786.1         81471-81609
            2693-2803           MH593786.1         82484-82594
            2804-2983           MH593786.1         82676-82855
            2984-3223           MH593786.1         82987-83226
            3224-3380           MH593786.1         84185-84341
            3381-3512           MH593786.1         84618-84749
            3513-3660           MH593786.1         85440-85587
            3661-3704           MH593786.1         87077-87120
            3705-3908           MH593786.1         87522-87725
            3909-3926           MH593786.1         88212-88229
            3927-12719          MH593786.1         88820-97612
            12720-12917         MH593786.1         98344-98541
            12918-13141         MH593786.1         98810-99033
            13142-13316         MH593786.1         99343-99517
            13317-13564         MH593786.1         100004-100251
            13565-13748         MH593786.1         100861-101044
            13749-13977         MH593786.1         101368-101596
            13978-14156         MH593786.1         102320-102498
            14157-14226         MH593786.1         102890-102959
            14227-14327         MH593786.1         103098-103198
            14328-14359         MH593786.1         103443-103474
            14360-14537         MH593786.1         104670-104847
            14538-14642         MH593786.1         105234-105338
            14643-14683         MH593786.1         105588-105628
            14684-14806         MH593786.1         105757-105879
            14807-14905         MH593786.1         106132-106230
            14906-15034         MH593786.1         106865-106993
            15035-15074         MH593786.1         107231-107270
            15075-15201         MH593786.1         107485-107611
            15202-15574         MH593786.1         107720-108092
FEATURES             Location/Qualifiers
     source          1..15574
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="11"
                     /map="11p15.5"
     gene            1..15574
                     /gene="MUC2"
                     /gene_synonym="MLP; MUC-2; SMUC"
                     /note="mucin 2, oligomeric mucus/gel-forming"
                     /db_xref="GeneID:4583"
                     /db_xref="HGNC:HGNC:7512"
                     /db_xref="MIM:158370"
     exon            1..104
                     /gene="MUC2"
                     /gene_synonym="MLP; MUC-2; SMUC"
                     /inference="alignment:Splign:2.1.0"
     CDS             29..15421
                     /gene="MUC2"
                     /gene_synonym="MLP; MUC-2; SMUC"
                     /note="mucin 2, intestinal/tracheal"
                     /codon_start=1
                     /product="mucin-2 precursor"
                     /protein_id="NP_002448.5"
                     /db_xref="GeneID:4583"
                     /db_xref="HGNC:HGNC:7512"
                     /db_xref="MIM:158370"
                     /translation="MGLPLARLAAVCLALSLAGGSELQTEGRTRNHGHNVCSTWGNFH
                     YKTFDGDVFRFPGLCDYNFASDCRGSYKEFAVHLKRGPGQAEAPAGVESILLTIKDDT
                     IYLTRHLAVLNGAVVSTPHYSPGLLIEKSDAYTKVYSRAGLTLMWNREDALMLELDTK
                     FRNHTCGLCGDYNGLQSYSEFLSDGVLFSPLEFGNMQKINQPDVVCEDPEEEVAPASC
                     SEHRAECERLLTAEAFADCQDLVPLEPYLRACQQDRCRCPGGDTCVCSTVAEFSRQCS
                     HAGGRPGNWRTATLCPKTCPGNLVYLESGSPCMDTCSHLEVSSLCEEHRMDGCFCPEG
                     TVYDDIGDSGCVPVSQCHCRLHGHLYTPGQEITNDCEQCVCNAGRWVCKDLPCPGTCA
                     LEGGSHITTFDGKTYTFHGDCYYVLAKGDHNDSYALLGELAPCGSTDKQTCLKTVVLL
                     ADKKKNVVVFKSDGSVLLNELQVNLPHVTASFSVFRPSSYHIMVSMAIGVRLQVQLAP
                     VMQLFVTLDQASQGQVQGLCGNFNGLEGDDFKTASGLVEATGAGFANTWKAQSSCHDK
                     LDWLDDPCSLNIESANYAEHWCSLLKKTETPFGRCHSAVDPAEYYKRCKYDTCNCQNN
                     EDCLCAALSSYARACTAKGVMLWGWREHVCNKDVGSCPNSQVFLYNLTTCQQTCRSLS
                     EADSHCLEGFAPVDGCGCPDHTFLDEKGRCVPLAKCSCYHRGLYLEAGDVVVRQEERC
                     VCRDGRLHCRQIRLIGQSCTAPKIHMDCSNLTALATSKPRALSCQTLAAGYYHTECVS
                     GCVCPDGLMDDGRGGCVVEKECPCVHNNDLYSSGAKIKVDCNTCTCKRGRWVCTQAVC
                     HGTCSIYGSGHYITFDGKYYDFDGHCSYVAVQDYCGQNSSLGSFSIITENVPCGTTGV
                     TCSKAIKIFMGRTELKLEDKHRVVIQRDEGHHVAYTTREVGQYLVVESSTGIIVIWDK
                     RTTVFIKLAPSYKGTVCGLCGNFDHRSNNDFTTRDHMVVSSELDFGNSWKEAPTCPDV
                     STNPEPCSLNPHRRSWAEKQCSILKSSVFSICHSKVDPKPFYEACVHDSCSCDTGGDC
                     ECFCSAVASYAQECTKEGACVFWRTPDLCPIFCDYYNPPHECEWHYEPCGNRSFETCR
                     TINGIHSNISVSYLEGCYPRCPKDRPIYEEDLKKCVTADKCGCYVEDTHYPPGASVPT
                     EETCKSCVCTNSSQVVCRPEEGKILNQTQDGAFCYWEICGPNGTVEKHFNICSITTRP
                     STLTTFTTITLPTTPTTFTTTTTTTTPTSSTVLSTTPKLCCLWSDWINEDHPSSGSDD
                     GDRETFDGVCGAPEDIECRSVKDPHLSLEQLGQKVQCDVSVGFICKNEDQFGNGPFGL
                     CYDYKIRVNCCWPMDKCITTPSPPTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTT
                     TPSPPITTTTTPPPTTTPSPPISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTP
                     PPTTTPSPPTTTPITPPASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTS
                     TTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTT
                     TPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPP
                     ITTTTTPPPTTTPSSPITTTPSPPTTTMTTPSPTTTPSSPITTTTTPSSTTTPSPPPT
                     TMTTPSPTTTPSPPTTTTTTLPPTTTSSPLTTTPLPPSITPPTFSPFSTTTPTTPCVP
                     LCNWTGWLDSGKPNFHKPGGDTELIGDVCGPGWAANISCRATMYPDVPIGQLGQTVVC
                     DVSVGLICKNEDQKPGGVIPMAFCLNYEINVQCCECVTQPTTMTTTTTENPTPTPITT
                     TTTVTPTPTPTSTQSTTPTPITTTNTVTPTPTPTGTQTPTPTPITTTTTMVTPTPTIT
                     STQTPTPTPITTTTVTPTPTPTSTQRTTPTSITTTTTVTPTPTPTGTQTPTTTPITTT
                     TTVTPTPTPTGTQTPTTTPISTTTTVTPTPTPTGTQTLTPTPITTTTTVTPTPTPTGT
                     QTPTSTPITTTTTVTPTPTPTGTQTPTLTPITTTTTVTPTPTPTGTQTPTTTPITTTT
                     TVTPTPTPTGTKSTTPTSITTTTMVTPTPPPTGTQTPTTTPITTTTTVTPTPTPTGTQ
                     TPTPTPITTTTTVTPTPTPTGTQTPTSTPITTNTTVTPTPTPTGTPSTTLTPITTTTT
                     VTPTPTPTGTQTPTSTPISTTTMVTPTPTPTGTQTPTPTPISTTTTVTPTPTPTGTQT
                     PTPTPITTTTTVTPTPTPTGTQTPTSTPITTTTTVTPTPTPTGTQTPTTTPITTNTTV
                     TPTPTPTGTQTPTTVLITTTTTMTPTPTPTSTKSTTVTPITTTTTVTPTPTPTGTQST
                     TLTPITTTTTVTPTPTPTGIQTPTTTPISTTTTVTPTPTPTGTQTPTSTPITTTTTVT
                     PTPTPTGTQTPTSTPISTTTTVTPTATPTGTQTPTLTPITTTTTVTPTPTPTGTKSTT
                     PTSITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTPTPITTTTTVTP
                     TPTPTSTQTPTSTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQAPTP
                     TAITTTTTGTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQSPTPTAITTTTTVTPT
                     PTPTGTQTPTTTPITTTTTVTPTPTPTGTQSTTLTPITTTTTVTPTPTPTGTQTPTST
                     PITTTITVTPTPTPTGTQTPTPTPISTTTTVTPTPTPTGTQTPTSTPITTTTTVTPTP
                     TPTGTQTPTTTPISTTTTVTPTPTPTGTQTPTSTPITTTTTVTPTPTPTGTQTPTTTP
                     ISTTTTVTPTPTPTGTQTPTSTPITTTTTVTPTPTPTGTQTPTPTPITTTTTVTPTPT
                     PTGTQTPTSTPITTTTTVTPTPTPTGTQTPTPTPITTTTTVTPTPTPTGTQTPTPTPI
                     TTTTTVTPTPTPTGTQTPTSTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP
                     TGTQSTTLTPITTTTTVTPTPTPTGTQTPTSTPITTITTVTPTPTPTGTQTPTPTPIS
                     TTTTVTPTPTPTGTQTPTMTPITTTTTVTPTPTPTGTQTPTTTPISTTTTVTPTPTPT
                     GTQTPTSTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQSTTLTPITT
                     TTTVTPTPTPTGTQTPTPTPISTTTTVTPTPTPTGTQTPTMTPITTTTTVTPTPTPTG
                     TQTPTTTPISTTTTVTPTPTPTGTQTPRSTPITTTTKVTPTPTPTGTQTPTPTPITTT
                     TTVTPTPTPTGTQAPTPAAITTTSTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT
                     QSTTLTPITTTTTVTPTPTPTGTQTPTSTPITTTTTVTPTPTPTGTQTPTPTPISTTS
                     TVTPTPTPTGTQTPTMTPITTTTTVTPTPTPTGTQTPTTTPISTTTTVTPTPTPTGTQ
                     NPTSTPITTTTTVTPTPTPTGTQTPTMTPITTTTTVTPTPTPTGTQAPTPTAITTTTT
                     VTPTPTPTGTQTPTTTPITTTTTVTPTPIPTGTQSTTLTPITTTTTVTPTPTPTGTQT
                     PTPIPISTTTTVTPTPTPTGTQTPTMTPITTTTTVTPTPTPTGTQTPTTTPISTTTTV
                     TPTPTPTGTQTPTSTPITTTTTVTPTPIPTGTQTPTTTPITTTTTVTPTPTPTGTQAP
                     TPTAITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPIPTGTQSTTLTPITTTTTVT
                     PTPTPTSTQTPTPTPISTTTTVTPTPTPTGTQTPTMTPITTTTTVTPTPTPTGTQTPT
                     TTPISTTTTVTPTPTPTGTQTPTSTPITTTTTVTPTPTSTGTQTPTTTPITTTTTVTP
                     TPTPTGTQAPTPTAITTTSTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQSPTP
                     TAITTTTTVTPTPTPTGTQTPTSTPITTTTTVTPTPTPTGTQTPTPTPISTTTTVTPT
                     PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTVLITTTTTMTPTPTPTSTKSTTVT
                     PITTTTTVTATPTPTGTQTPTMIPISTTTTVTPTPTPTTGSTGPPTHTSTAPIAELTT
                     SNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTSTAPPSTPTAPTTTSGGHTLS
                     PPPSTTTSPPGTPTRGTTTGSSSAPTPSTVQTTTTSAWTPTPTPLSTPSIIRTTGLRP
                     YPSSVLICCVLNDTYYAPGEEVYNGTYGDTCYFVNCSLSCTLEFYNWSCPSTPSPTPT
                     PSKSTPTPSKPSSTPSKPTPGTKPPECPDFDPPRQENETWWLCDCFMATCKYNNTVEI
                     VKVECEPPPMPTCSNGLQPVRVEDPDGCCWHWECDCYCTGWGDPHYVTFDGLYYSYQG
                     NCTYVLVEEISPSVDNFGVYIDNYHCDPNDKVSCPRTLIVRHETQEVLIKTVHMMPMQ
                     VQVQVNRQAVALPYKKYGLEVYQSGINYVVDIPELGVLVSYNGLSFSVRLPYHRFGNN
                     TKGQCGTCTNTTSDDCILPSGEIVSNCEAAADQWLVNDPSKPHCPHSSSTTKRPAVTV
                     PGGGKTTPHKDCTPSPLCQLIKDSLFAQCHALVPPQHYYDACVFDSCFMPGSSLECAS
                     LQAYAALCAQQNICLDWRNHTHGACLVECPSHREYQACGPAEEPTCKSSSSQQNNTVL
                     VEGCFCPEGTMNYAPGFDVCVKTCGCVGPDNVPREFGEHFEFDCKNCVCLEGGSGIIC
                     QPKRCSQKPVTHCVEDGTYLATEVNPADTCCNITVCKCNTSLCKEKPSVCPLGFEVKS
                     KMVPGRCCPFYWCESKGVCVHGNAEYQPGSPVYSSKCQDCVCTDKVDNNTLLNVIACT
                     HVPCNTSCSPGFELMEAPGECCKKCEQTHCIIKRPDNQHVILKPGDFKSDPKNNCTFF
                     SCVKIHNQLISSVSNITCPNFDASICIPGSITFMPNGCCKTCTPRNETRVPCSTVPVT
                     TEVSYAGCTKTVLMNHCSGSCGTFVMYSAKAQALDHSCSCCKEEKTSQREVVLSCPNG
                     GSLTHTYTHIESCQCQDTVCGLPTGTSRRARRSPRHLGSG"
     exon            105..375
                     /gene="MUC2"
                     /gene_synonym="MLP; MUC-2; SMUC"
                     /inference="alignment:Splign:2.1.0"
     exon            376..490
                     /gene="MUC2"
                     /gene_synonym="MLP; MUC-2; SMUC"
                     /inference="alignment:Splign:2.1.0"
     exon            491..581
                     /gene="MUC2"
                     /gene_synonym="MLP; MUC-2; SMUC"
                     /inference="alignment:Splign:2.1.0"
     exon            582..691
                     /gene="MUC2"
                     /gene_synonym="MLP; MUC-2; SMUC"
                     /inference="alignment:Splign:2.1.0"
     exon            692..902
                     /gene="MUC2"
                     /gene_synonym="MLP; MUC-2; SMUC"
                     /inference="alignment:Splign:2.1.0"
     exon            903..1028
                     /gene="MUC2"
                     /gene_synonym="MLP; MUC-2; SMUC"
                     /inference="alignment:Splign:2.1.0"
     exon            1029..1146
                     /gene="MUC2"
                     /gene_synonym="MLP; MUC-2; SMUC"
                     /inference="alignment:Splign:2.1.0"
     exon            1147..1285
                     /gene="MUC2"
                     /gene_synonym="MLP; MUC-2; SMUC"
                     /inference="alignment:Splign:2.1.0"
     exon            1286..1396
                     /gene="MUC2"
                     /gene_synonym="MLP; MUC-2; SMUC"
                     /inference="alignment:Splign:2.1.0"
     exon            1397..1466
                     /gene="MUC2"
                     /gene_synonym="MLP; MUC-2; SMUC"
                     /inference="alignment:Splign:2.1.0"
     exon            1467..1604
                     /gene="MUC2"
                     /gene_synonym="MLP; MUC-2; SMUC"
                     /inference="alignment:Splign:2.1.0"
     exon            1605..1769
                     /gene="MUC2"
                     /gene_synonym="MLP; MUC-2; SMUC"
                     /inference="alignment:Splign:2.1.0"
     exon            1770..1864
                     /gene="MUC2"
                     /gene_synonym="MLP; MUC-2; SMUC"
                     /inference="alignment:Splign:2.1.0"
     exon            1865..1991
                     /gene="MUC2"
                     /gene_synonym="MLP; MUC-2; SMUC"
                     /inference="alignment:Splign:2.1.0"
     exon            1992..2247
                     /gene="MUC2"
                     /gene_synonym="MLP; MUC-2; SMUC"
                     /inference="alignment:Splign:2.1.0"
     exon            2248..2300
                     /gene="MUC2"
                     /gene_synonym="MLP; MUC-2; SMUC"
                     /inference="alignment:Splign:2.1.0"
     exon            2301..2401
                     /gene="MUC2"
                     /gene_synonym="MLP; MUC-2; SMUC"
                     /inference="alignment:Splign:2.1.0"
     exon            2402..2553
                     /gene="MUC2"
                     /gene_synonym="MLP; MUC-2; SMUC"
                     /inference="alignment:Splign:2.1.0"
     exon            2554..2692
                     /gene="MUC2"
                     /gene_synonym="MLP; MUC-2; SMUC"
                     /inference="alignment:Splign:2.1.0"
     exon            2693..2803
                     /gene="MUC2"
                     /gene_synonym="MLP; MUC-2; SMUC"
                     /inference="alignment:Splign:2.1.0"
     exon            2804..2983
                     /gene="MUC2"
                     /gene_synonym="MLP; MUC-2; SMUC"
                     /inference="alignment:Splign:2.1.0"
     exon            2984..3223
                     /gene="MUC2"
                     /gene_synonym="MLP; MUC-2; SMUC"
                     /inference="alignment:Splign:2.1.0"
     exon            3224..3380
                     /gene="MUC2"
                     /gene_synonym="MLP; MUC-2; SMUC"
                     /inference="alignment:Splign:2.1.0"
     exon            3381..3512
                     /gene="MUC2"
                     /gene_synonym="MLP; MUC-2; SMUC"
                     /inference="alignment:Splign:2.1.0"
     exon            3513..3660
                     /gene="MUC2"
                     /gene_synonym="MLP; MUC-2; SMUC"
                     /inference="alignment:Splign:2.1.0"
     exon            3661..3704
                     /gene="MUC2"
                     /gene_synonym="MLP; MUC-2; SMUC"
                     /inference="alignment:Splign:2.1.0"
     exon            3705..3908
                     /gene="MUC2"
                     /gene_synonym="MLP; MUC-2; SMUC"
                     /inference="alignment:Splign:2.1.0"
     exon            3909..3926
                     /gene="MUC2"
                     /gene_synonym="MLP; MUC-2; SMUC"
                     /inference="alignment:Splign:2.1.0"
     exon            3927..12719
                     /gene="MUC2"
                     /gene_synonym="MLP; MUC-2; SMUC"
                     /inference="alignment:Splign:2.1.0"
     exon            12720..12917
                     /gene="MUC2"
                     /gene_synonym="MLP; MUC-2; SMUC"
                     /inference="alignment:Splign:2.1.0"
     exon            12918..13141
                     /gene="MUC2"
                     /gene_synonym="MLP; MUC-2; SMUC"
                     /inference="alignment:Splign:2.1.0"
     exon            13142..13316
                     /gene="MUC2"
                     /gene_synonym="MLP; MUC-2; SMUC"
                     /inference="alignment:Splign:2.1.0"
     exon            13317..13564
                     /gene="MUC2"
                     /gene_synonym="MLP; MUC-2; SMUC"
                     /inference="alignment:Splign:2.1.0"
     exon            13565..13748
                     /gene="MUC2"
                     /gene_synonym="MLP; MUC-2; SMUC"
                     /inference="alignment:Splign:2.1.0"
     exon            13749..13977
                     /gene="MUC2"
                     /gene_synonym="MLP; MUC-2; SMUC"
                     /inference="alignment:Splign:2.1.0"
     exon            13978..14156
                     /gene="MUC2"
                     /gene_synonym="MLP; MUC-2; SMUC"
                     /inference="alignment:Splign:2.1.0"
     exon            14157..14226
                     /gene="MUC2"
                     /gene_synonym="MLP; MUC-2; SMUC"
                     /inference="alignment:Splign:2.1.0"
     exon            14227..14327
                     /gene="MUC2"
                     /gene_synonym="MLP; MUC-2; SMUC"
                     /inference="alignment:Splign:2.1.0"
     exon            14328..14359
                     /gene="MUC2"
                     /gene_synonym="MLP; MUC-2; SMUC"
                     /inference="alignment:Splign:2.1.0"
     exon            14360..14537
                     /gene="MUC2"
                     /gene_synonym="MLP; MUC-2; SMUC"
                     /inference="alignment:Splign:2.1.0"
     exon            14538..14642
                     /gene="MUC2"
                     /gene_synonym="MLP; MUC-2; SMUC"
                     /inference="alignment:Splign:2.1.0"
     exon            14643..14683
                     /gene="MUC2"
                     /gene_synonym="MLP; MUC-2; SMUC"
                     /inference="alignment:Splign:2.1.0"
     exon            14684..14806
                     /gene="MUC2"
                     /gene_synonym="MLP; MUC-2; SMUC"
                     /inference="alignment:Splign:2.1.0"
     exon            14807..14905
                     /gene="MUC2"
                     /gene_synonym="MLP; MUC-2; SMUC"
                     /inference="alignment:Splign:2.1.0"
     exon            14906..15034
                     /gene="MUC2"
                     /gene_synonym="MLP; MUC-2; SMUC"
                     /inference="alignment:Splign:2.1.0"
     exon            15035..15074
                     /gene="MUC2"
                     /gene_synonym="MLP; MUC-2; SMUC"
                     /inference="alignment:Splign:2.1.0"
     exon            15075..15201
                     /gene="MUC2"
                     /gene_synonym="MLP; MUC-2; SMUC"
                     /inference="alignment:Splign:2.1.0"
     exon            15202..15574
                     /gene="MUC2"
                     /gene_synonym="MLP; MUC-2; SMUC"
                     /inference="alignment:Splign:2.1.0"
     regulatory      15554..15559
                     /regulatory_class="polyA_signal_sequence"
                     /gene="MUC2"
                     /gene_synonym="MLP; MUC-2; SMUC"
                     /note="hexamer: AATAAA"
     polyA_site      15574
                     /gene="MUC2"
                     /gene_synonym="MLP; MUC-2; SMUC"
                     /note="major polyA site"
ORIGIN      
        1 gcaacccaca ccgcccctgc cagccaccat ggggctgcca ctagcccgcc tggcggctgt
       61 gtgcctggcc ctgtctttgg cagggggctc ggagctccag acagagggca gaacccgaaa
      121 ccacggccac aacgtctgca gcacctgggg caacttccac tacaagacct tcgacgggga
      181 cgtcttccgc ttccccggcc tctgcgacta caacttcgcc tccgactgcc gaggctccta
      241 caaggaattt gctgtgcacc tgaagcgggg tccgggccag gctgaggccc ccgccggggt
      301 ggagtccatc ctgctgacca tcaaggatga caccatctac ctcacccgcc acctggctgt
      361 gcttaacggg gccgtggtca gcaccccgca ctacagcccc gggctgctca ttgagaagag
      421 cgatgcctac accaaagtct actcccgcgc cggcctcacc ctcatgtgga accgggagga
      481 tgcactcatg ctggagctgg acactaagtt ccggaaccac acctgtggcc tctgcgggga
      541 ctacaacggc ctgcagagct attcagaatt cctctctgac ggcgtgctct tcagtcccct
      601 ggagtttggg aacatgcaga agatcaacca gcccgatgtg gtgtgtgagg atcccgagga
      661 ggaggtggcc cccgcatcct gctccgagca ccgcgccgag tgtgagaggc tgctgaccgc
      721 cgaggccttc gcggactgtc aggacctggt gccgctggag ccgtatctgc gcgcctgcca
      781 gcaggaccgc tgccggtgcc cgggcggtga cacctgcgtc tgcagcaccg tggccgagtt
      841 ctcccgccag tgctcccacg ccggcggccg gcccgggaac tggaggaccg ccacgctctg
      901 ccccaagacc tgccccggga acctggtgta cctggagagc ggctcgccct gcatggacac
      961 ctgctcacac ctggaggtga gcagcctgtg cgaggagcac cgcatggacg gctgtttctg
     1021 cccagaaggc accgtatatg acgacatcgg ggacagtggc tgcgttcctg tgagccagtg
     1081 ccactgcagg ctgcacggac acctgtacac accgggccag gagatcacca atgactgcga
     1141 gcagtgtgtc tgtaacgctg gccgctgggt gtgcaaagac ctgccctgcc ccggcacctg
     1201 tgccctggaa ggcggctccc acatcaccac cttcgatggg aagacgtaca ccttccacgg
     1261 ggactgctac tatgtcctgg ccaagggtga ccacaacgat tcctacgctc tcctgggcga
     1321 gctggccccc tgtggctcca cagacaagca gacctgcctg aagacggtgg tgctgctggc
     1381 tgacaagaag aagaatgtgg tggtcttcaa gtccgatggc agtgtactgc tcaacgagct
     1441 gcaggtgaac ctgccccacg tgaccgcgag cttctctgtc ttccgcccgt cttcctacca
     1501 catcatggtg agcatggcca ttggcgtccg gctgcaggtg cagctggccc cagtcatgca
     1561 actctttgtg acactggacc aggcctccca ggggcaggtg cagggcctct gcgggaactt
     1621 caacggcctg gaaggtgacg acttcaagac ggccagcggg ctggtggagg ccacgggggc
     1681 cggctttgcc aacacctgga aggcacagtc aagctgccat gacaagctgg actggttgga
     1741 cgatccctgc tccctgaaca tcgagagcgc caactacgcc gagcactggt gctccctcct
     1801 gaagaagaca gagaccccct ttggcaggtg ccactcggct gtggaccctg ctgagtatta
     1861 caagaggtgc aaatatgaca cgtgtaactg tcagaacaat gaggactgcc tgtgcgccgc
     1921 cctgtcctcc tacgcgcgcg cctgcaccgc caagggcgtc atgctgtggg gctggcggga
     1981 gcatgtctgc aacaaggatg tgggctcctg ccccaactcg caggtcttcc tgtacaacct
     2041 gaccacctgc cagcagacct gccgctccct ctccgaggcc gacagccact gtctcgaggg
     2101 ctttgcgcct gtggacggct gcggctgccc tgaccacacc ttcctggacg agaagggccg
     2161 ctgcgtaccc ctggccaagt gctcctgtta ccaccgcggt ctctacctgg aggcggggga
     2221 tgtggtcgtc aggcaggaag aacgatgtgt gtgccgggat gggcggctgc actgtaggca
     2281 gatccggctg atcggccaga gctgcacggc cccaaagatc cacatggact gcagcaacct
     2341 gactgcactg gccacctcga agccccgagc cctcagctgc cagacgctgg ccgccggcta
     2401 ttaccacaca gagtgtgtca gtggctgtgt gtgccccgac gggctgatgg atgacggccg
     2461 gggtggctgc gtggtggaga aggaatgccc ttgcgtccat aacaacgacc tgtattcttc
     2521 cggcgccaag atcaaggtgg actgcaatac ctgcacctgc aagagaggac gctgggtgtg
     2581 cacccaggct gtgtgccatg gcacctgctc catttacggg agtggccact acatcacctt
     2641 tgatgggaag tactacgact ttgacggaca ctgctcctac gtggctgttc aggactactg
     2701 cggccagaac tcctcactgg gctcattcag catcatcacc gagaacgtcc cctgtggcac
     2761 tacgggcgtc acctgctcca aggccatcaa gatcttcatg gggaggacgg agctgaagtt
     2821 ggaagacaag caccgtgtgg tgatccagcg tgatgagggt caccacgtgg cctacaccac
     2881 gcgggaggtg ggccagtacc tggtggtgga gtccagcacg ggcatcatcg tcatctggga
     2941 caagaggacc accgtgttca tcaagctggc tccctcctac aagggcaccg tgtgtggcct
     3001 gtgtgggaac tttgaccacc gctccaacaa cgacttcacc acgcgggacc acatggtggt
     3061 gagcagcgag ctggacttcg ggaacagctg gaaggaggcc cccacctgcc cagatgtgag
     3121 caccaacccc gagccctgca gcctgaaccc gcaccgccgc tcctgggccg agaagcagtg
     3181 cagcatcctc aaaagcagcg tgttcagcat ctgccacagc aaggtggacc ccaagccctt
     3241 ctacgaggcc tgtgtgcacg actcgtgctc ctgtgacacg ggtggggact gtgagtgctt
     3301 ctgctctgcc gtggcctcct acgcccagga gtgtaccaaa gagggggcct gcgtgttctg
     3361 gaggacgccg gacctgtgcc ccatattctg cgactactac aaccctccgc atgagtgtga
     3421 gtggcactat gagccatgtg ggaaccggag cttcgagacc tgcaggacca tcaacggcat
     3481 ccactccaac atctccgtgt cctacctgga gggctgctac ccccggtgcc ccaaggacag
     3541 gcccatctat gaggaggatc tgaagaagtg tgtcactgca gacaagtgtg gctgctatgt
     3601 cgaggacacc cactacccac ctggagcatc ggttcccacc gaggagacct gcaagtcctg
     3661 cgtgtgtacc aactcctccc aagtcgtctg caggccggag gaaggaaaga ttcttaacca
     3721 gacccaggat ggcgccttct gctactggga gatctgtggc cccaacggga cggtggagaa
     3781 gcacttcaac atctgttcca ttacgacacg cccgtccacc ctgaccacct tcaccaccat
     3841 caccctcccc accaccccca ccaccttcac cactaccacc accaccacca ccccgacctc
     3901 cagcacagtt ttatcaacaa ctccgaagct gtgctgcctc tggtctgact ggatcaatga
     3961 ggaccacccc agcagtggca gcgacgacgg tgaccgagaa acatttgatg gggtctgcgg
     4021 ggcccctgag gacatcgagt gcaggtcggt caaggatccc cacctcagct tggagcagct
     4081 aggccagaag gtgcagtgtg atgtctctgt tgggttcatt tgcaagaatg aagaccagtt
     4141 tggaaatgga ccatttggac tgtgttacga ctacaagata cgtgtcaatt gttgctggcc
     4201 catggataag tgtatcacca ctcccagccc tccaactacc actcccagcc ctccaccaac
     4261 cagcacgacc acccttccac caaccaccac ccccagccct ccaaccacca ccacaaccac
     4321 ccctccacca accaccaccc ccagccctcc aataaccacc acgaccaccc ctccaccaac
     4381 caccactccc agccctccaa taagcaccac aaccacccct ccaccaacca ccactcccag
     4441 ccctccaacc accactccca gccctccaac caccactccc agccctccaa caaccaccac
     4501 aaccacccct ccaccaacca ccactcccag ccctccaacg actacgccca tcactccacc
     4561 agccagcact accacccttc caccaaccac cactcccagc cctccaacaa ccaccacaac
     4621 cacccctcca ccaaccacca ctcccagtcc tccaacgact acgcccatca ctccaccaac
     4681 cagcactact acccttccac caaccaccac tcccagccct ccaccaacca ccacaaccac
     4741 ccctccacca accaccactc ccagccctcc aacaaccacc actcccagtc ctccaacaat
     4801 caccacaacc acccctccac caaccaccac tcccagccct ccaacaacga ccacaaccac
     4861 ccctccacca accaccactc ccagccctcc aacgactaca cccatcactc caccaaccag
     4921 cactaccacc cttccaccaa ccaccactcc cagccctcca ccaaccacca caaccacccc
     4981 tccaccaacc accactccca gccctccaac aaccaccact cccagccctc caataaccac
     5041 cacaaccacc cctccaccaa ccaccactcc cagctctcca ataaccacca ctcccagccc
     5101 tccaacaacc accatgacca ccccttcacc aaccaccacc cccagctctc caataaccac
     5161 cacaaccacc ccttcctcaa ctaccactcc cagccctcca ccaaccacca tgaccacccc
     5221 ttcaccaacc accactccca gccctccaac aaccaccacg accacccttc caccaaccac
     5281 cacttccagc cctctaacaa ctactcctct acctccatca ataactcctc ctacattttc
     5341 accattctca acgacaaccc ctactacccc atgcgtgcct ctctgcaatt ggactggctg
     5401 gctggattct ggaaaaccca actttcacaa accaggtgga gacacagaat tgattggaga
     5461 cgtctgtgga ccaggctggg cagctaacat ctcttgcaga gccaccatgt atcctgatgt
     5521 tcccattgga cagcttggac aaacagtggt gtgtgatgtc tctgtggggc tgatatgcaa
     5581 aaatgaagac caaaagccag gtggggtcat ccctatggcc ttctgcctca actacgagat
     5641 caacgttcag tgctgtgagt gtgtcaccca acccaccacc atgacaacca ccaccacaga
     5701 gaacccaact ccgacaccaa tcaccaccac cactacggtg accccaaccc caacacccac
     5761 cagcacacag agtacaacac caacacccat caccaccacc aatacggtaa ccccaacccc
     5821 aacccccact ggcacacaga ccccaacccc gacacccatc accaccacca ccactatggt
     5881 gaccccaacc ccaacaatca ccagcacaca gaccccaacc ccgacaccca tcaccaccac
     5941 tacggtgacc ccaaccccaa cacccaccag cacacagaga acaacaccga catccatcac
     6001 caccaccacc acggtgaccc caaccccaac acccaccggc acacagaccc caaccacgac
     6061 acccatcacc accaccacca cggtgacccc aaccccaaca cccaccggca cacagacccc
     6121 aacaacgaca cccatcagca ccaccaccac ggtgacccca accccaacac ccactggaac
     6181 acagacccta accccaacac ccatcaccac caccactacg gtgaccccaa cccctacacc
     6241 caccggcaca cagaccccaa catcgacacc catcaccacc accactacgg tgaccccaac
     6301 accaacaccc actggcacac agaccccaac cctgacaccc atcaccacca ccactacggt
     6361 gaccccaacc ccaacaccca ccggcacaca gaccccaacc acgacaccca tcaccaccac
     6421 cactacggtg accccaaccc caacacccac cggcacaaag agtacaaccc cgacatccat
     6481 caccaccacc actatggtga ccccaacccc accacccact ggcacacaga ccccaaccac
     6541 gacacccatc accaccacca ctacggtgac cccaacccca acacccaccg gcacacagac
     6601 cccaaccccg acacccatca ccaccaccac cacggtgacc ccaaccccaa cacccaccgg
     6661 cacacagacc ccaacatcga cacccatcac caccaacact acggtgaccc caaccccaac
     6721 accaaccggc acaccgagta caaccctgac acccatcacc accaccacta cggtgacccc
     6781 aaccccaaca cccaccggca cacagacccc aacatcgaca cccatcagca ccaccactat
     6841 ggtgacccca accccaacac ccaccggcac acagacccca acccctacac ccatctccac
     6901 caccactacg gtgaccccaa ccccaacacc caccggcaca cagaccccaa ccccgacacc
     6961 catcaccacc accaccacgg tgaccccaac cccaacaccc accggcacac agaccccaac
     7021 atcgacaccc atcaccacca ccactacggt gaccccaacc ccaacaccca ccggcacaca
     7081 gaccccaacc acgacaccca tcaccaccaa caccacggtg accccaaccc cgacacccac
     7141 cggcacacag accccaacca cggtactcat caccaccacc actacgatga caccaacccc
     7201 aacacccacc agcacaaaga gtacaaccgt gacacccatc accaccacca ctactgtgac
     7261 cccaacccca acacccaccg gcacacagag tacaaccctg acacccatca ccaccaccac
     7321 tacggtgacc ccaaccccaa cacccaccgg catacagacc ccaacaacga cacccatcag
     7381 caccaccacc accgtgaccc caaccccaac acccaccggc acacagaccc caacatcgac
     7441 acccatcacc accaccacta cggtgacccc aacccctaca cccactggca cacagacccc
     7501 aacatcgaca cccatcagca ccaccactac ggtgacccca acagcaacac ccaccggcac
     7561 acagacccca accctgacac ccatcaccac caccactacg gtgaccccaa ccccaacacc
     7621 caccggcaca aagagtacaa ccccgacatc catcaccacc accactacgg tgaccccaac
     7681 cccaacaccc actggcacac agaccccaac cacgacaccc atcaccacca ccaccacggt
     7741 gaccccaacc ccaacaccca ccggcacaca gaccccaacc ccgacaccca tcaccaccac
     7801 caccacggtg accccaaccc caacacccac cagcacacag accccaacat cgacacccat
     7861 caccaccacc actacggtga ccccaacccc aacacccact ggcacacaga ccccaaccac
     7921 gacacccatt accacgacca ccacggtgac cccaacccca acacccaccg gcacacaggc
     7981 cccaacccca acagccatca ccaccaccac tacggggacc ccaaccccaa cacccaccgg
     8041 cacacagacc ccaaccacga cacccatcac caccaccact acggtgacac caaccccaac
     8101 acccaccggc acacagtccc caaccccaac agccatcacc accaccacta cggtgacccc
     8161 aaccccaaca cccaccggca cacagacccc aaccacgaca cccatcacca ccaccaccac
     8221 ggtgacccca accccgacac ccaccggcac acagagtaca accctgacac ccatcaccac
     8281 caccaccacg gtgacaccaa ccccaacacc cactggcaca cagaccccaa catcgacacc
     8341 catcaccacc accattacgg tgaccccaac cccaacaccc accggcacac agaccccaac
     8401 cccgacaccc atctccacca ccactacggt gaccccaacc ccaacaccca ccggcacaca
     8461 gaccccaaca tcgacaccca tcaccaccac caccacggtg accccaaccc caacacccac
     8521 cggcacacag accccaacaa cgacacccat cagcaccacc accacggtga ccccaacccc
     8581 aacacccacc ggcacacaga ccccaacatc gacacccatc accaccacca ccacggtgac
     8641 cccaacccca acacccaccg gcacacagac cccaaccacg acacccatca gcaccaccac
     8701 cacggtgacc ccaaccccaa cacccaccgg cacacagacc ccaacatcga cacccatcac
     8761 caccaccacc acggtgaccc caaccccaac acccaccggc acacagaccc caaccccgac
     8821 acccatcacc accaccacca cggtgacccc aaccccaaca cccaccggca cacagacccc
     8881 aacatcgaca cccatcacca ccaccaccac ggtgacccca accccaacac ccaccggcac
     8941 acagacccca accccgacac ccatcaccac caccaccacg gtgaccccaa ccccaacacc
     9001 caccggcaca cagaccccaa ccccgacacc catcaccacc accaccacgg tgaccccaac
     9061 cccaacaccc accggcacac agaccccaac atcgacaccc atcaccacca ccactacggt
     9121 gaccccaacc ccaacaccca ccggcacaca gaccccaacc acgacaccca tcaccaccac
     9181 caccacggtg accccaaccc caacacccac tggcacacag agtacaaccc tgacacccat
     9241 caccaccacc accacggtga caccaacccc aacacccacc ggcacacaga ccccaacatc
     9301 gacacccatc accaccatca ctacggtgac cccaacccca acacccaccg gcacacagac
     9361 cccaaccccg acacccatct ccaccaccac tacagtgacc ccaaccccaa cacccaccgg
     9421 cacacagacc ccaaccatga cacccatcac caccaccacc acggtgaccc caaccccaac
     9481 acccaccggc acacagaccc caacaacgac acccatcagc accaccacca cggtgacccc
     9541 aaccccaaca cccaccggca cacagacccc aacatcgaca cccatcacca ccaccactac
     9601 ggtgacccca accccaacac ccaccggcac acagacccca accacgacac ccatcaccac
     9661 caccaccacg gtgaccccaa ccccaacacc caccggcaca cagagtacaa ccctgacacc
     9721 catcaccacc accaccacgg tgacaccaac cccaacaccc accggcacac agaccccaac
     9781 cccgacaccc atctccacca ccactacggt gaccccaacc ccaacaccca ccggcacaca
     9841 gaccccaacc atgacaccca tcaccaccac caccacggtg accccaaccc caacacccac
     9901 cggcacacag accccaacaa cgacacccat cagcaccacc accacggtga ccccaacccc
     9961 aacacccacc ggcacacaga ccccaagatc gacacccatc accaccacca ctaaggtgac
    10021 cccaacccca acacccaccg gcacacagac cccaaccccg acacccatca ccaccaccac
    10081 cacggtgacc ccaaccccaa cacccactgg cacacaggcc ccaaccccag cagccatcac
    10141 caccaccagt acggtgaccc caaccccaac acccaccggc acacagaccc caaccacgac
    10201 acccatcacc accaccacca cggtgacccc aaccccaaca cccaccggca cacagagtac
    10261 aaccctgaca cccatcacca ccaccaccac ggtgacacca accccaacac ccaccggcac
    10321 acagacccca acatcgacac ccatcaccac caccactacg gtgaccccaa ccccaacacc
    10381 caccggcaca cagaccccaa ccccgacacc catctccacc accagtacgg tgaccccaac
    10441 cccaacaccc accggcacac agaccccaac catgacaccc atcaccacca ccaccacggt
    10501 gaccccaacc ccaacaccca ccggcacaca gaccccaaca acgacaccca tcagcaccac
    10561 caccacggtg accccaaccc caacacccac cggcacacag aacccaacat cgacacccat
    10621 caccaccacc actacggtga ccccaacccc aacacccacc ggcacacaga ccccaaccat
    10681 gacacccatc accaccacca ccacggtgac cccaacccca acacccactg gcacacaggc
    10741 cccaacccca acagccatca ccaccaccac tacggtgacc ccaaccccaa cacccaccgg
    10801 cacacagacc ccaaccacga cacccatcac caccaccacc acggtgaccc caaccccaat
    10861 acccaccggc acacagagta caaccctgac acccatcacc accaccacca cggtgacacc
    10921 aaccccaaca cccaccggca cacagacccc aaccccgata cccatctcca ccaccactac
    10981 ggtgacccca accccaacac ccaccggcac acagacccca accatgacac ccatcaccac
    11041 caccaccacg gtgaccccaa ccccaacacc caccggcaca cagaccccaa caacgacacc
    11101 catcagcacc accaccacgg tgaccccaac cccaacaccc accggcacac agaccccaac
    11161 atcgacaccc atcaccacca ccactacggt gaccccaacc ccaataccca ccggcacaca
    11221 gaccccaacc acgacaccca tcaccaccac caccacggtg accccaaccc caacacccac
    11281 tggcacacag gccccaaccc caacagccat caccaccacc actacggtga ccccaacccc
    11341 aacacccacc ggcacacaga ccccaaccac gacacccatc accaccacca ccacggtgac
    11401 cccaacccca atacccaccg gcacacagag tacaaccctg acacccatca ccaccaccac
    11461 cacggtgaca ccaaccccaa cacccaccag cacacagacc ccaaccccga cacccatctc
    11521 caccaccact acggtgaccc caaccccaac acccaccggc acacagaccc caaccatgac
    11581 acccatcacc accaccacca cggtgacccc aaccccaaca cccaccggca cacagacccc
    11641 aacaacgaca cccatcagca ccaccaccac ggtgacccca accccaacac ccaccggcac
    11701 acagacccca acatcgacac ccatcaccac caccactaca gtgaccccaa ccccaacatc
    11761 caccggcaca cagaccccaa ccacgacacc catcaccacc accaccacgg tgaccccaac
    11821 cccaacaccc actggcacac aggccccaac cccaacagcc atcaccacca ccagtacggt
    11881 gaccccaacc ccaacaccca ccggcacaca gaccccaacc acgacaccca tcaccaccac
    11941 cactacggtg acaccaaccc caacacccac cggcacacag tccccaaccc caacagccat
    12001 caccaccacc actacggtga ccccaacccc aacacccacc ggcacacaga ccccaacatc
    12061 gacacccatc accaccacca ctacggtgac cccaacccca acacccaccg gcacacagac
    12121 cccaaccccg acacccatct ccaccaccac tacggtgacc ccaaccccaa cacccaccgg
    12181 cacacagacc ccaaccacga cacccatcac caccaccacc acggtgaccc caaccccgac
    12241 acccaccggc acacagaccc caaccacggt actcatcacc accaccacta cgatgacccc
    12301 aaccccaaca cccaccagca caaagagtac aaccgtgaca cccatcacca ccacaactac
    12361 ggtgaccgca accccaacac ccaccggcac acagacccca accatgatac ccatcagcac
    12421 caccactacg gtgaccccaa ccccaacacc caccactgga agcacggggc cccccaccca
    12481 cacaagcaca gcacccattg ctgagttgac cacatccaat cctccgcctg agtcctcaac
    12541 ccctcagacc tctcggtcca cctcttcccc tctcacggag tcaaccaccc ttctgagtac
    12601 cctaccacct gccattgaga tgaccagcac ggccccaccc tccacaccca cggcacccac
    12661 gaccacgagc ggaggccaca cactgtctcc accgcccagc accaccacgt cccctccagg
    12721 cacccccact cgcggtacca cgaccgggtc atcttcagcc cccaccccca gcactgtgca
    12781 gacgaccacc accagtgcct ggaccccaac gccgacccca ctctccacac ccagcatcat
    12841 caggaccaca ggcctgaggc cctacccttc ctctgtgctt atctgctgtg tcctgaacga
    12901 cacctactac gcaccaggtg aggaggtgta caacggcaca tacggagaca cctgttattt
    12961 cgtcaactgc tcactgagct gtacgttgga gttctataac tggtcctgcc catccacgcc
    13021 ctccccaaca cccacgccct ccaagtcgac gcccacgcct tccaagccat cgtccacgcc
    13081 ctccaagccg acgcccggca ccaagccccc cgagtgccca gactttgatc ctcccagaca
    13141 ggagaacgag acttggtggc tgtgcgactg cttcatggcc acgtgcaagt acaacaacac
    13201 ggtggagatc gtgaaggtgg agtgtgagcc gccgcccatg cccacctgct ccaacggcct
    13261 ccaacccgtg cgcgtcgagg accccgacgg ctgctgctgg cactgggagt gcgactgcta
    13321 ctgcacgggc tggggcgacc cgcactatgt caccttcgac ggactctact acagctacca
    13381 gggcaactgc acctacgtgc tggtggagga gatcagcccc tccgtggaca acttcggagt
    13441 ttacatcgac aactaccact gcgatcccaa cgacaaggtg tcctgtcccc gcaccctcat
    13501 cgtgcgccac gagacccagg aggtgctgat caagaccgtg catatgatgc ccatgcaggt
    13561 gcaggtgcag gtgaacaggc aggcggtggc actgccctac aagaagtacg ggctggaggt
    13621 gtaccagtct ggcatcaact acgtggtgga catccccgag ctgggtgtcc tcgtctccta
    13681 caatggcctg tccttctccg tcaggctgcc ctaccaccgg tttggcaaca acaccaaggg
    13741 ccagtgtggc acctgcacca acaccacctc cgacgactgc attctgccca gcggggagat
    13801 cgtctccaac tgtgaggctg cggctgacca gtggctggtg aacgacccct ccaagccaca
    13861 ctgcccccac agcagctcca cgaccaagcg cccggccgtc actgtgcccg ggggcggtaa
    13921 aacgacccca cacaaggact gcaccccatc tcccctctgc cagctcatca aggacagcct
    13981 gtttgcccag tgccacgcac tggtgccccc gcagcactac tacgatgcct gcgtgttcga
    14041 cagctgcttc atgccgggct cgagcctgga gtgcgccagt ctgcaggcct acgcagccct
    14101 ctgtgcccag cagaacatct gcctcgactg gcggaaccac acgcatgggg cctgcttggt
    14161 ggagtgccca tctcacaggg agtaccaggc ctgtggccct gcagaagagc ccacgtgcaa
    14221 atccagctcc tcccagcaga acaacacagt cctggtggaa ggctgcttct gtcctgaggg
    14281 caccatgaac tacgctcctg gctttgatgt ctgcgtgaag acctgcggct gtgtgggacc
    14341 tgacaatgtg cccagagagt ttggggagca cttcgagttc gactgcaaga actgtgtctg
    14401 cctggagggt ggaagtggca tcatctgcca acccaagagg tgcagccaga agcccgttac
    14461 ccactgcgtg gaagacggca cctacctcgc cacggaggtc aaccctgccg acacctgctg
    14521 caacattacc gtctgcaagt gcaacaccag cctgtgcaaa gagaagccct ccgtgtgccc
    14581 gctgggattc gaagtgaaga gcaagatggt gcctggaagg tgctgtcctt tctactggtg
    14641 tgagtccaag ggggtgtgtg ttcacgggaa tgctgagtac cagcccggtt ctccagttta
    14701 ttcctccaag tgccaggact gcgtgtgcac ggacaaggtg gacaacaaca ccctgctcaa
    14761 cgtcatcgcc tgcacccacg tgccctgcaa cacctcctgc agccctggct tcgaactcat
    14821 ggaggccccc ggggagtgct gtaagaagtg tgaacagacg cactgtatca tcaaacggcc
    14881 cgacaaccag cacgtcatcc tgaagcccgg ggacttcaag agcgacccga agaacaactg
    14941 cacattcttc agctgcgtga agatccacaa ccagctcatc tcgtccgtct ccaacatcac
    15001 ctgccccaac tttgatgcca gcatttgcat cccgggctcc atcacattca tgcccaatgg
    15061 atgctgcaag acctgcaccc ctcgcaatga gaccagggtg ccctgctcca ccgtccccgt
    15121 caccacggag gtttcgtacg ccggctgcac caagaccgtc ctcatgaatc attgctccgg
    15181 gtcctgcggg acatttgtca tgtactcggc caaggcccag gccctggacc acagctgctc
    15241 ctgctgcaaa gaggagaaaa ccagccagcg tgaggtggtc ctgagctgcc ccaatggcgg
    15301 ctcgctgaca cacacctaca cccacatcga gagctgccag tgccaggaca ccgtctgcgg
    15361 gctccccacc ggcacctccc gccgggcccg gcgctcccct aggcatctgg ggagcgggtg
    15421 agcggggtgg gcacagcccc cttcactgcc ctcgacagct ttacctcccc cggaccctct
    15481 gagcctccta agctcggctt cctctcttca gatatttatt gtctgagtct ttgttcagtc
    15541 cttgctttcc aataataaac tcagggggac atgc
//
