LOCUS       XM_047434508            4763 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens methenyltetrahydrofolate synthetase domain
            containing (MTHFSD), transcript variant X19, mRNA.
ACCESSION   XM_047434508
VERSION     XM_047434508.1
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000016.10) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4763
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="16"
     gene            1..4763
                     /gene="MTHFSD"
                     /note="methenyltetrahydrofolate synthetase domain
                     containing; Derived by automated computational analysis
                     using gene prediction method: Gnomon. Supporting evidence
                     includes similarity to: 1 mRNA, 2 ESTs, 27 long SRA reads,
                     and 98% coverage of the annotated genomic feature by
                     RNAseq alignments, including 1 sample with support for all
                     annotated introns"
                     /db_xref="GeneID:64779"
                     /db_xref="HGNC:HGNC:25778"
                     /db_xref="MIM:616820"
     CDS             170..799
                     /gene="MTHFSD"
                     /codon_start=1
                     /product="methenyltetrahydrofolate synthase
                     domain-containing protein isoform X15"
                     /protein_id="XP_047290464.1"
                     /db_xref="GeneID:64779"
                     /db_xref="HGNC:HGNC:25778"
                     /db_xref="MIM:616820"
                     /translation="MESQNLADFPRPVHHRIPNFKGASHAAEQLPRLQAFKTARTIKV
                     NPDAPQKSARFFVLESKKTLLVPTPRLRTGLFNKITPPPGATKDILRKCATSQGVRNY
                     SVPIGLDSRVLVDLVVVGSVAVSEKGWRIGKGEGYADLEYAMMVSMGAVSKETPVVTI
                     VHDCQVVDIPEELVEEHDITVDYILTPTRVIATGCKRPKPMGITWFKIR"
     polyA_site      4763
                     /gene="MTHFSD"
                     /experiment="COORDINATES: polyA evidence [ECO:0006239]"
ORIGIN      
        1 actacgcgcc agaacctgcg ccgggaagcg tcgcacagcg actgcatcac catggagccg
       61 agggcaggtg gggggcctgg cggggctccg gggcggctgg gaatggggag ggacagccgg
      121 gaccgtaggt gtctccaaac aggacatacg tgaacaaatt tggggctaca tggaatcaca
      181 aaatttagct gactttcccc gacctgttca tcacaggata cccaacttta agggcgcttc
      241 tcatgctgcc gagcaactcc cacgcttgca ggcgttcaaa acggccagga ccattaaagt
      301 aaatcctgat gccccccaga aaagtgctcg cttcttcgtc cttgaaagca aaaaaacatt
      361 gttggttcca acaccacgac tgagaacggg attgtttaat aagatcacac caccccctgg
      421 ggcaactaaa gacatcttga gaaaatgtgc cacctctcag ggtgtgagga actacagtgt
      481 ccccataggc ttggactcca gagtcctcgt ggatttagtt gtggtgggat ccgtcgccgt
      541 ttctgaaaaa ggctggagaa tcgggaaggg agaaggctac gccgatctgg aatatgccat
      601 gatggtatcc atgggcgccg tcagcaagga gacgccggtg gtcaccatcg tccacgactg
      661 ccaggtcgtg gacatccctg aagagcttgt tgaggagcac gacatcactg tggactacat
      721 cctcactcca accagagtca tcgccacagg ctgcaagcgc ccaaagccaa tgggaatcac
      781 ctggttcaag attaggtaat ggcacaggtt gcaaattagt ctgcagtagg agtttgaccc
      841 tgcaaatcag cctgtaggtt atgatgctgt ctctgctggc aaacagccag aattactgag
      901 aagacatttg tgcttcgtgt ggacaaaact actggtcaaa taagcatacg tgtccacgtc
      961 tcccattctt taatcccaaa tcattcaccg tttgaatccc tcctttgggc atggaaaatt
     1021 aacaacatca cctctaagga tgaacacaga atacctgctg cttttgccac agcccagccg
     1081 ggactttccc tgcaggtgtc ctgggcaggc actgctgggg actcccaggt gtgcactcct
     1141 cggttggccg ctgatgaacg cagagggaac agcctttgta acccagagtg tatgggcggc
     1201 cctctaagcg caccaggagc actgggaaag aaggtggtca ctgctcttcc aggaaatgaa
     1261 aatatccctt gatgtctttc ttaagagtct ttcacttggg aactctggtc cacagcttcc
     1321 ttgtaagtgg aagccaatgc acgagacaga gcataaggct ggcggctcct cagagccgag
     1381 aacagggatg gtgggaaggt tgcacaaggg cattagccac agcgaagctg ctggcagtcc
     1441 ctctaggcct gcgcgtcata gaaggggccc attgcagccg tattaggggg agcctggaca
     1501 gcctcctctg gcagagagct aggaacagcc tggttacatt ctgaagattt taactagaaa
     1561 agtagcaaca aatgaagtca tcggacacgt taggtgaata tatcctccta cagaaaagca
     1621 aaccaaactc agccagggtt cctgagggtc agcactgtgg gggagggagg gcatcggggg
     1681 cttcgctgtt tgtcgagacc ctcttccagg aaagtcactg tttatgaggc ctcagcaaga
     1741 atctcagact tttcaaaggc catctctcat tttgggtcct gtgttctcag tttcaccacc
     1801 tgataatccc tttgcatggt cagaggaaat cagtcacttt ctacagctcc cagtgtttct
     1861 gttttagtct cgctagccat gcagccaaag tgagtttcat caacatttgt tgggagaaaa
     1921 aaaaaatctc taaattccat taaagagttt gaatgtggaa ggcggacagt tcagtgctag
     1981 gttataatat tgtttcaaat tgactttggc aaatatttgg catacctctc catgatatta
     2041 tagtgatagg tttataggtt tataggtttt agaatctaag aatttacctc ttggctatct
     2101 tactggaata tctgggatgc attatagatc tcttgatgaa ggatgtgaag gaagtacaaa
     2161 ctgccttttc ttcacccatt ttcaatacgc aaagacagtt cagcatctaa ttccctggcc
     2221 tttgttccac ctttccagta gttgacgtcc tgccctgtct tacagaccag tctaatacac
     2281 gctctgtttg agtgcagtta ctgtaaacag cgcatctcct tgattgacca tcaacatccg
     2341 gtgggctctt ctcagcttgt gtctcatgat tttaaagaaa ggaaaccagg tggccagtga
     2401 gtgtattgct gagtttagca gtcaagagtt tcccacttca tagctctatc tgtaacttcc
     2461 aacacactct ccaagccctc tcgtttgtct tagaaataaa ggcagtgcat gtagaatgcc
     2521 caggacgatg cttgggagca tggccgcagt caacatcact gtcgcaaatg cgaggtaggc
     2581 tgttaataaa gttgagaaat cttcctggac gccatgcatg tttcttcttt ctctgtgctg
     2641 ctggcagaat tcttaggatg gtccttctgg gtagctcact gagccaagat ggggtcctgc
     2701 acgtgtctcc ctatggccac gggttgtacc tctcagtgga ggacaaggag agaaaggcac
     2761 tgaccccggc tctccagccc tttggctgct ccataccgcc tgtgaccatg caggtgcttt
     2821 gcagagaccc cccacaagta gccgttgttc ttcctcctcc atatcatctt cagcaaagga
     2881 agcctggtag ggttgggtaa ggggcttaaa atgcattcca gcactctgca ccctcatcag
     2941 aaactttctg gcaggaagag agagaggtac agagacattc cccagaaggc tctgcttttg
     3001 ctcctccttt ctagaaggca cattgtctgc tctgtcctcg tgtgctcttc tgtctctggg
     3061 ggcgatcgcc tcacccacag acccgtgaaa ctcagggtga cttggccaca tccaaaccac
     3121 aagatgcata gccgctgctg ccccatctcc cagtcaccgt accctgaaaa cccaggactc
     3181 cctgaacccc tagctacacc aaggatctct gccaggctgg agatggtacc agagacctgg
     3241 gcctgaagct ggaacgtggt cctgaacctc tgggcagttc gtccagctcc attgatcttc
     3301 tgatccttgg agacagtcgt gcgatgtctc tccctgtgac agccgtgtgt caggtagtct
     3361 gtagtgggct gagagccatt tggctgcctc agctctgtgc cgtagcaaac cgaaaatggc
     3421 tgaagccctg gacccgctag tgtcgagcag ccctggccac tgaccagtgc ctgcccttgt
     3481 cgggagtgaa atgcagagtc ccagccagct cccagggctg agtggtgtcc tatgagtcac
     3541 tgacaacaga agaacggaac ttcctgttga gacccgtggt cacctgctgg acccgagtga
     3601 gcacctggac agcagcagca ggtgaagcct ctgtggggag acccgggtct gccactgccg
     3661 ccgccaccct ggaagctctg ttctgcccaa gctgcacctg gaccgtggag acccaccaca
     3721 ccattgtagt gtttccctag agctggcctg agctgggggc aggaatgata tatgttaaga
     3781 ataccttgga gacagagagg aatggtagga catggctaca gactccagaa cctcaactgt
     3841 gccgaaggca aggccagcct gagtgggaga ctgagggctc aggagaagcc actcgggcac
     3901 ccacaagcct gtggtccccg tcaccagacc cacaaaccag agggcctttt ggcctttgcc
     3961 cagtggaagg actgtcagtc acacacatct tctcacccgt cctgtgctcc tcaccatcag
     4021 cacatggctc ctgattacca cggggttggc gaggacacca tagaccaagg cccgtgcatc
     4081 tgactttcct gggtcaactc atttgctcct taatgaggga aactggattc ttccagagcc
     4141 acgctcgtgc ttatactcaa ggaaacaatt ctgtagcttt caaagcatgg cccgctcttc
     4201 cccacacagc ctgctgggga gtgtggttct cagatggcca cagtatgctg catgatctac
     4261 agatacctca agaaaaagga tttgagaaca gggctcctct gtgagcagca gtcctgggac
     4321 agcaaagccc aatttcagat cccgcataaa acacaattgt tctctgcaaa taatgcagct
     4381 aactgtgaac caacccctac ccacaactgg gccagtatgt ttagagagct gagagaggct
     4441 ttcattgaaa aagaattact gtatttgacc tgataattta ccttctagga atcagtccta
     4501 gagaaatatg tagaaattca gataaggact tatctgaatc tctatagaag acatgcagtg
     4561 ccttaaaatg ggggtggggg gagtccattt aagtgcatac agctttttaa agaatatttt
     4621 gtggcaggag aaagtgcatg tggtataaag tagaaaaggc acgatatgat attatacatg
     4681 cttgatatgg aatttcatat tctgctcatg ttaaagggca gagagaaaag acggcgagga
     4741 aatacagcag aatattaaca gta
//
