LOCUS       XM_011517627            8980 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens mitochondrial fission regulator 1 (MTFR1),
            transcript variant X3, mRNA.
ACCESSION   XM_011517627
VERSION     XM_011517627.4
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000008.11) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Apr 5, 2022 this sequence version replaced XM_011517627.3.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8980
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="8"
     gene            1..8980
                     /gene="MTFR1"
                     /gene_synonym="CHPPR; FAM54A2"
                     /note="mitochondrial fission regulator 1; Derived by
                     automated computational analysis using gene prediction
                     method: Gnomon. Supporting evidence includes similarity
                     to: 11 ESTs, 63 long SRA reads, and 87% coverage of the
                     annotated genomic feature by RNAseq alignments, including
                     8 samples with support for all annotated introns"
                     /db_xref="GeneID:9650"
                     /db_xref="HGNC:HGNC:29510"
                     /db_xref="MIM:619414"
     CDS             396..1511
                     /gene="MTFR1"
                     /gene_synonym="CHPPR; FAM54A2"
                     /codon_start=1
                     /product="mitochondrial fission regulator 1 isoform X1"
                     /protein_id="XP_011515929.1"
                     /db_xref="GeneID:9650"
                     /db_xref="HGNC:HGNC:29510"
                     /db_xref="MIM:619414"
                     /translation="MLGWIKRLIRMVFQQVGVSMQSVLWSRKPYGSSRSIVRKIGTNL
                     SLIQCPRVQFQINSHATEWSPSHPGEDAVASFADVGWVAKEEGECSARLRTEVRSRPP
                     LQDDLLFFEKAPSRQISLPDLSQEEPQLKTPALANEEALQKICALENELAALRAQIAK
                     IVTQQEQQNLTAGDLDSTTFGTIPPHPPPPPPPLPPPALGLHQSTSAVDLIKERREKR
                     ANAGKTLVKNNPKKPEMPNMLEILKEMNSVKLRSVKRSEQDVKPKPVDATDPAALIAE
                     ALKKKFAYRYRSDSQDEVEKGIPKSESEATSERVLKRLVKVRTCWTRRPMANPTEDKF
                     ISLKRIRTMTKTIQTTIIHGRKYCGIYIIKWLRSFFC"
     polyA_site      8980
                     /gene="MTFR1"
                     /gene_synonym="CHPPR; FAM54A2"
                     /experiment="COORDINATES: polyA evidence [ECO:0006239]"
ORIGIN      
        1 cccaggctgg agtgcagtgg cgtgatctgg gctcgataca acctccacct cccagctgcc
       61 tgccttggcc ccccaaagtg cggagattgc agcctctgcc cggccgccac cccgtctggg
      121 aagtgaggag cgtctctgcc tggccgccca tcgtctggga tgtgaggagc ctctctgcct
      181 ggctgcccag tctgggatgt gaggagcgtc tctgcccggc cgccccatct gagaagtgag
      241 gagaccctct gcctggcaac cgccccgtct gagaagtgag gagcccctcc gcccggcagc
      301 cacaccgtct gagaatgtgt tttatggacc atgtgctgct atgtatgcct gaagaagtac
      361 ttgaaatgca aatttgggga gactttgcca tataaatgct tggctggatt aagcgcctaa
      421 ttaggatggt ttttcaacaa gttggagtaa gcatgcaatc ggtactttgg tctaggaagc
      481 catatggttc gtctcgaagt atcgtaagga aaattggtac taatttgtct ctgattcagt
      541 gtccaagagt tcagtttcag attaacagcc atgcaacaga atggagtccc agccacccag
      601 gagaggatgc agtggcgtct tttgctgatg ttggatgggt agccaaagaa gaaggagagt
      661 gttcagcaag actaaggaca gaggtcagat caaggccacc ccttcaggat gaccttcttt
      721 tctttgagaa ggccccaagc agacagattt ccttaccaga cttgtctcaa gaagagcctc
      781 agctgaagac cccagcgctg gcaaatgagg aagcactgca gaagatttgc gctctcgaaa
      841 atgaacttgc tgctctcaga gctcagattg ccaaaattgt gacccagcag gagcagcaaa
      901 atctcactgc aggtgactta gattctacca catttggtac cataccacca caccctccac
      961 ctcccccacc gcccctgcct ccccctgcac tggggctcca ccaaagtaca tctgctgttg
     1021 atctgattaa agaacgaaga gagaaaagag ccaatgctgg aaagactttg gttaagaaca
     1081 atccaaagaa acctgaaatg ccaaatatgc tagagatcct taaagagatg aacagtgtaa
     1141 aacttcggtc agtgaagagg tcagagcaag atgtgaagcc caagccagtg gatgctactg
     1201 accctgctgc cctcatagca gaggctctga aaaagaaatt tgcttatcgg tatcgaagtg
     1261 atagccaaga tgaagttgaa aaaggaattc caaagtctga atcagaggcc acctcagaga
     1321 gagtgttgaa aagactcgtt aaagtcagaa cctgctggac aagaaggcct atggcaaatc
     1381 ctactgaaga taaatttata agccttaaga gaataaggac tatgacaaaa acaatccaaa
     1441 ccacaataat tcatggtagg aaatattgtg gcatctacat aataaaatgg ttgaggtcct
     1501 tcttttgtta attttgaggc ctataattgc tccttaactg gtcaggtatc ttagatatca
     1561 gctggctcac aggagaatgt atcttcataa tataaaccca aacgttgctt ataataaact
     1621 gtacatataa aaaatcttaa aagaaaagtt caatattgca atatagatgt ctaatttcta
     1681 ggtaaattta gtaaacagaa tatgttcaac atggagaaaa tcacactcca gaaataagtt
     1741 aaaaatattt caacatctaa aaaaaaattc agcagcaccc acagatacag cacatagaag
     1801 aaattaaaaa attatgaata gttttaataa ataacactaa tatcatatgt ctttaacctg
     1861 ttgatatcga tctccctcta tattttaagc tctctctctc tttaaaaaga cctgaccctg
     1921 ggtaaagggt agaggatgga tcaaagaaca gataatcctg gctgggcgca cgcagtggct
     1981 cacgcggtgg ctcacgcatg taatcccagc actttgggag gccagggcgg gcggatcacc
     2041 tgaggtaaga gttcgagacc agcctggcca acatggtgaa accccatctc tactaaaaat
     2101 acaaaggtta gccaggcgtg gtggtgggtg cctgtaatcc cagctacttg ggaggctgag
     2161 gcaggagaat cgcttgaacc tggaaggtgg aggctgcagt gagccacgat tgagccactg
     2221 cactccagcc tgggcaacag atcgagactc cgagactcca tctctcaaaa aaaaaaaaaa
     2281 aaaaaaaaag aagaagaaga aagaaggaaa tatcctgaaa gcagggataa cggttagtta
     2341 ggagaatacc agaacaacct cagacagtgg tgataaatga ctggttcaag gagaataaga
     2401 gataacgagg cagaaaagag atgaatagaa taggctatgt aagcatacaa aaacccaaag
     2461 gatttaatga gactggattt aagcaatgaa agaacagaaa gagacaacaa ttttacaaca
     2521 gggaaattaa cagtgagttt aggataaaag taaacaggtg cagaaaataa gtgggttgag
     2581 gagctgtaag cagagaacat tctagcttta atgaatttaa tacacatatc cagaattttg
     2641 caatcagaac acctagaaac tatttttatt tcagcatgca tgtaaatttt tgtatcatta
     2701 gggaaaatag tcttattttt aattctatac aaggtagagg gcacattata gtctttcaaa
     2761 gcttcagtac ctctgaaggt ttaaacacat cctgcaaggt tgctttagtg tttgtatctt
     2821 tgccaagtct gagattatag gaagtgaatg ggtttgtggc ataaatcaca aattcctaat
     2881 ccaaggaact tcacagggaa gaagaggggt aaaaaaggac aactttgcct ccaggtaaat
     2941 aaactactga tatcttcaac tagtgcaagg gagaaaggaa ataccccaca aggaagaaac
     3001 cttaagattc ataactggaa ataaaagaag gataatcctc ctggtcatta agtccaaggc
     3061 agctcaactt tactgtgcat aaactcaagc ctagggttaa actggccagg tgcggtggtt
     3121 catgcctgta atcccagcac tttgggaggc caaggcaggc agatcacttg aggtcaggag
     3181 ttcaagacca gtctgaccaa tatggtgaaa ccctatcttt aataaaaata caaaaaaaaa
     3241 ttagccaggt gtggtggcac acacctgtaa tcccagctac ttgggaggct gaggtgggag
     3301 aatcacttga acctgggaga cggaggctgc agtgagctga gatcgtgcca ctgcactcca
     3361 gcctgggcga cagattgaga ctctgtctca aaaaaaaaaa ttaagaaaaa gttttgtaag
     3421 ctaactcctg cagagaacaa gttcaggcta atgtttagga caatcagagg agtcagtgga
     3481 agaagggaag gcctgaagat gactaacaga ttttagtcat agcaggagca cgtgctcatt
     3541 tctctgatta gatcacattt cacaaaacac actagattac aatttcaaaa agaattccaa
     3601 gctgtgtgat aagcagaacc tattataagc agcaaagaat aatgcatttt tctctattaa
     3661 aaaaaactcc tctaaattat attaccatgg tggcttaaag agacatattc ttgttttgta
     3721 ataactatag gaccaagtct atagcaagag tccattttca actacaactt acacatttgt
     3781 caccttttat gaacagcatg atgagatcga gaggataatc tgctgctctt aacactgagc
     3841 tgcctccagt gttctaaata ccatactaca aagcttccac atcactggat caggatataa
     3901 gtatagatac caaaacctca agcccggttc tgcttcatat taatttgaac catttttttg
     3961 tcattaagtt tcatttatta tccaatttga ccttctttat ctcttaaaag gaatatttaa
     4021 cccatttatc tttattacta acattgatat gtttggtctt ccttctcttg tcttttagat
     4081 ttattttatt tgctcctggt ttcctagtga tttagatagt acatatccta ttttaatttc
     4141 attagagata cttctaacaa tctaatcatt tttaatgtcc ctctcccact aaaacgtccc
     4201 attatgcccc ctatttaaaa cttctaacag ttatattttt cgaattctct tattttacta
     4261 aattcagtga atgttagggg gtaggctgga gactccaaat acaattgtac atttctttat
     4321 acaaatatca atatttagac ttaactcttt tactgatttc cttacccaca gccaatcctt
     4381 atttattgca ataccaaaac atacttttac ttaaactttc caatgagcaa tacgttcaca
     4441 tgagtcaaaa ttcaaaaggt ctacaactaa gtttctttcc cctcccatct cctcaagcca
     4501 cccagtttct atcctggaag caaccaatgt tatcagtttc tgctacgtta ttgcagaaaa
     4561 actatgtatt gaatcatcct tgcttccttt tctaaaacaa ccccactatc gctgaagtat
     4621 tactctttcg tgctgttgga aatcctcatg ctaataaata tttttaaaag attttttgta
     4681 ctgacattta tagtgagaat attataaaaa gttatatttg ctttataaaa ttactctgaa
     4741 tggttccctc tttataatca gaaagtttaa agagctttga aactaatcat caatctttta
     4801 aagatcttaa ataatttgcc tataaaattc tctggccctc aggcttttag agagataact
     4861 cttacacaac tttctctaac atattggttc tcaggagtct ttcgcactct taaaaattat
     4921 tgacaaccca aataacttta actttatatg ggttatagct atcaatattt accacagaaa
     4981 ttaagtattt accatagaaa ttaaattttt aatatttaaa tatttagtta atttaaaaat
     5041 atataaaaca aaatttattt gaaaatatct aatggctaaa tattgtttaa atttatttaa
     5101 aaaatttatt actataaacc cataacatgt aacataaata acatttttat taaaaataac
     5161 tatattttcc aaaacaaaga aaaatttaat gagaaacgtc cggctgtttc tcatatctgc
     5221 taatacactg aatttactga gacatcacac atcatgcagc cttggaaaac tccactgtat
     5281 ccttgagaga gaataaaagc aaaaaaggca aataacatct tagtattacg atgaaaatag
     5341 ttttaacctc acagaccgca ctttaagtac tgctggatta atttatgttt tctacattca
     5401 gttctgataa actgtaattt ttaagaaaat tttctggatc atacaagtgt tcaaatatat
     5461 ttttggggtc aagcaaaata gtccatttcg attcttatat tttctcttta tctgtggtgt
     5521 tttcccctct tagtttttga gtatgcacgt tagctccatt caatctttaa gttagctagc
     5581 aacttatctc ttttattgca aacaaccagc tcttagttac agagttctac ttttatttta
     5641 gtttactagt tcattgattg ctgtttttta tctttaacaa ctactttatc ttttcttagt
     5701 gtattttgat attatttttc taatttcttg agttggacta cttagttgac ttatttcatt
     5761 ctttctcatt tatgaatata agtatttttt aaggctatga attttcctgc aagcactgca
     5821 ttagctgaat ttcatagatt ttcccatcta gtctttaatt atcacgtttt tatggtctac
     5881 ctctttgacc caagaagtac ttatttcaga atttgaaaaa tttccaggtg gccaggcctt
     5941 tttgttttct agctttgcta ttaatttcta gtatcagtga tcctacgtcc tctgtcagtt
     6001 gcctctctta tttcttccct tttctttgag acgaagtctc gctctgtagc caaggcttga
     6061 gtgaagtggt gtgatcttgg ctaactgcaa cctccgcctc ccaggttcga gtgattctcc
     6121 tgcctcagcc tcctgagtgg ctgggattac aggcacgcac cactgcacct ggctaatttt
     6181 tactattttt agtagagatg gagtttcacc atgttggcca ggctggtctt aaactcctga
     6241 cctcaggtga tccacctgcc tcggctttcc aaagtgctag attacgggcg tgagccacca
     6301 tgcccggcct cttccctttt ctttgtagca aaagtctcta aaagagttgt ttatacttgc
     6361 tatatctaat tcccatcttt ctgttctctc ttaaattcac tttaatttca ggcttcccct
     6421 acaccatatc cacattgcta aatcaatgtt attgatttag cattcctcat cttacctgaa
     6481 ttatcagcat aatttggcaa agttaatcaa ccaaaatttg atttttttta atgcatggtg
     6541 tgaacagggt ccaagattca cttgatttag tgaaattgct atttctaccc attgcattat
     6601 ttatcttcta cctacttcat taccacactt gtcacaaatc aaatatccat atatgtgtgg
     6661 gttatttctg gattctatag tatgccttta ttctattgtc agtccttgaa ttaacatcac
     6721 cttgacttaa ttattattgt ttataataag tttgatatct atgagatgta aactccataa
     6781 tttcattctt cttcctaatt gtcttggcta ttcttggagc tgggattttt tcactgtgat
     6841 ttcactaaac ctatacagat caatttagga aagaagaaaa actggcatct ttaaatactg
     6901 aatcctccaa tccataaata acagtatata tatttctatt taagttatct ttaatttttc
     6961 tatgtaatca cttacagttt tctatgtaga gttatacata tctttagtta gatttatccc
     7021 tacatatttg atgtttcttg atacaaattc aaattatata ttatgttaat tttgtcactg
     7081 ttactttaca gaactcccac tacgtactga ctttgtatcc aggaaaactg ctaacttcac
     7141 ttattaatcc taacaatttt ctaagtacat aactatgtca tccataaaaa tgatactttt
     7201 tcttttctag tccttatact tttcatttct ttttcttgca ttactatact ggccagaacc
     7261 tctgaaacaa tactgaatag gaaagatgat gaaagatatt cttgatttct catcgcagaa
     7321 agaatgtttt aatattgcgc attaaatatg atgtttgcta tgggttttgt agctaatgtt
     7381 tcagactgtt taagtttttc tctgttccta gcttgctcag aattataaga aagaacaaat
     7441 actcaatttt atcaaatgct tttttttttt tttttttttt tgagacagag ttttgttctt
     7501 gttgcccaga ctggagtgca atgcaatcct ggctaaccgc aacctctgcc tcctgggttc
     7561 aagcgattct cctgcctcgg cctcccaagt agctgggatt acaggcatgc accaccacgc
     7621 ctggctaatt ttgtattttt agtagagacg gggtttctct atgttggtca ggctggtctc
     7681 gaactcccga cctcagatga tccgcccgcc tcagcctccc aaagtgctgg gattacaagc
     7741 gtgagccaca acttttctcc tttattttat taatatagtg aattacactg attgattttt
     7801 cactgttaaa ccaatcttat attcctggaa aaatactaat taggtcaaaa tatattaatt
     7861 ctccctttgt gttatagata taatttgata atatgttatt taggatgttt cctctatatt
     7921 catgagcgat ttggctgtta ttttttgttc tttccacaac cttgtcatgt tgtagtatca
     7981 agattacatg ctagccttac gtaacaaatt gtgaagtgta tccttttcag agtttgtgga
     8041 tgatattttt agtttgacag tttatttttt tctagcacat cagagctatt tttcctttgt
     8101 cttctacctt tttagtttct gtggaaaatg aaaccatctg tttctggcaa tctcataatt
     8161 gctcctttga aagtaatact ccactacccc tcattacttt taattctttg tctttgattt
     8221 tggttttcat agttatactc tggtacactt aggtgtgatt ttcttttaat gttactctgc
     8281 ttgagattta taatacttcc tgaatctgtc ccttaatgtc ttttaccaac ttctagagat
     8341 ttctcagcca ttgcttcttt aaagactgct cctgctacat ttttccctct cctctccttc
     8401 taggacctta attacttttt caaaacattt tgtgccagat tacagatggg agattaaaaa
     8461 ggttttgacc ttgcatccct ttgacaacca gggttgggag agggctgtgt cttccctcca
     8521 tgaccctgag caagctgtgt gacacagctc atcaacagaa tatggaaatg cgatgttatg
     8581 ccagggtctg ggcccagatc ttcagacact atgagtcctc acacttcctc tttcttgaaa
     8641 tgcttgctct gggagaaagt agctgccatg taattagtcc aactacccta agacttccct
     8701 gagactgcca tttatggaga gagaaaaatg ttggcaccac acctaagagt gcagaagcca
     8761 tcttggaggt tccagccctg gaagatgaca tgagatggac caaggccctg gacataaggc
     8821 tccagtgtca ccatcccagc catttttaag ctgtctgaac cattccaatc aaagaccaag
     8881 acactgtaga gcacaagcaa gccaaacttg atatataccc tgactgaatt cctgattctc
     8941 ggaatcatga gcattaaaaa tagtggttat tttatgccaa
//
