LOCUS       NM_001105569            1339 bp    mRNA    linear   PRI 03-AUG-2024
DEFINITION  Homo sapiens mesogenin 1 (MSGN1), mRNA.
ACCESSION   NM_001105569 XM_292850 XM_939861
VERSION     NM_001105569.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1339)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   2  (bases 1 to 1339)
  AUTHORS   Yin,Y., Morgunova,E., Jolma,A., Kaasinen,E., Sahu,B.,
            Khund-Sayeed,S., Das,P.K., Kivioja,T., Dave,K., Zhong,F.,
            Nitta,K.R., Taipale,M., Popov,A., Ginno,P.A., Domcke,S., Yan,J.,
            Schubeler,D., Vinson,C. and Taipale,J.
  TITLE     Impact of cytosine methylation on DNA binding specificities of
            human transcription factors
  JOURNAL   Science 356 (6337) (2017)
   PUBMED   28473536
REFERENCE   3  (bases 1 to 1339)
  AUTHORS   Vaquerizas,J.M., Kummerfeld,S.K., Teichmann,S.A. and Luscombe,N.M.
  TITLE     A census of human transcription factors: function, expression and
            evolution
  JOURNAL   Nat Rev Genet 10 (4), 252-263 (2009)
   PUBMED   19274049
  REMARK    Review article
REFERENCE   4  (bases 1 to 1339)
  AUTHORS   Yoon,J.K., Moon,R.T. and Wold,B.
  TITLE     The bHLH class protein pMesogenin1 can specify paraxial mesoderm
            phenotypes
  JOURNAL   Dev Biol 222 (2), 376-391 (2000)
   PUBMED   10837126
  REMARK    GeneRIF: Described the cloning, expression and function of the
            mouse and frog mesogenin 1.
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC093731.2.
            
            On May 17, 2019 this sequence version replaced NM_001105569.2.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript is intronless :: SRR1803617.389370.1, SRR1163655.45040.1
                                        [ECO:0000345]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000281047.4/ ENSP00000281047.3
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1339              AC093731.2         61390-62728
FEATURES             Location/Qualifiers
     source          1..1339
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="2"
                     /map="2p24.2"
     gene            1..1339
                     /gene="MSGN1"
                     /gene_synonym="MSOG; pMsgn1"
                     /note="mesogenin 1"
                     /db_xref="GeneID:343930"
                     /db_xref="HGNC:HGNC:14907"
                     /db_xref="MIM:612209"
     exon            1..1339
                     /gene="MSGN1"
                     /gene_synonym="MSOG; pMsgn1"
                     /inference="alignment:Splign:2.1.0"
     CDS             60..641
                     /gene="MSGN1"
                     /gene_synonym="MSOG; pMsgn1"
                     /note="pMesogenin1; paraxial mesoderm-specific mesogenin1"
                     /codon_start=1
                     /product="mesogenin-1"
                     /protein_id="NP_001099039.1"
                     /db_xref="CCDS:CCDS42657.1"
                     /db_xref="GeneID:343930"
                     /db_xref="HGNC:HGNC:14907"
                     /db_xref="MIM:612209"
                     /translation="MDNLRETFLSLEDGLGSSDSPGLLSSWDWKDRAGPFELNQASPS
                     QSLSPAPSLESYSSSPCPAVAGLPCEHGGASSGGSEGCSVGGASGLVEVDYNMLAFQP
                     THLQGGGGPKAQKGTKVRMSVQRRRKASEREKLRMRTLADALHTLRNYLPPVYSQRGQ
                     PLTKIQTLKYTIKYIGELTDLLNRGREPRAQSA"
ORIGIN      
        1 ggcagaattt tctttctcac ttgccaggga gccattcctt ctgcagctgt ctcgcaggca
       61 tggacaacct gcgcgagact ttcctcagcc tcgaggatgg cttgggctcc tctgacagcc
      121 ctggcctgct gtcttcctgg gactggaagg acagggcagg gccctttgag ctgaatcagg
      181 cctccccctc tcagagcctt tccccggctc catcgctgga atcctattct tcttctccct
      241 gtccagctgt ggctgggctg ccctgtgagc acggcggggc cagcagtggg ggcagcgaag
      301 gctgcagtgt cggtggggcc agtggcctgg tagaggtgga ctacaatatg ttagctttcc
      361 agcccaccca ccttcagggc ggtggtggcc ccaaggccca gaagggcacc aaagtcagga
      421 tgtctgtcca gcggaggcgg aaagccagcg agagggagaa gctcaggatg aggaccttgg
      481 cagatgccct gcacaccctc cggaattacc tgccacctgt ctacagccag agaggccagc
      541 ctctcaccaa gatccagaca ctcaagtaca ccatcaagta catcggggaa ctcacagacc
      601 tccttaaccg cggcagagag cccagagccc agagcgcgtg agctccatcc ggggaaactg
      661 accggttcca gcctcctgag caggagtaga ggagttttga agacctggat atcttattga
      721 acaatgatcg gcgtagagtg atttttatgt agtaagcctg ataatcttgt gatctgaaaa
      781 accctaaggg aattcacatg taacctgttg gacccaccag aacacttacc tgccagatga
      841 gcagagactt tcacctccag ttttttccac ccatctggga ggctcatcct ttgcaaacag
      901 acagattatt ttgcccttct ctgtctgttc aaggtatttt aaagggtcag tgattttaaa
      961 tgcatttttt tcaataatgt aaaagtgtta atctcttgcc attttggcgt tgagaccttt
     1021 tcttctgttg ctaacaaaac ctgtattttg tataggatcc agtgtgatat ctggattctt
     1081 atttagaaag atttgtgcca agtaaagggc tttagtgctc ctgttttcat ttcgtgtgta
     1141 tatgtgtgtg tgtttgtgtt tgactgaaat catgctgttg cagggaccaa aatcacttaa
     1201 atgcggaagg cactggtgtc atgataaatg gaaagtcaca ggcagacagg ctaagttaag
     1261 acagtgaaga ttccaaaagc cagagcctcc tcttcacagg caaacagctt gtgtgacagg
     1321 gaaggagggt acggggagg
//
