LOCUS       NM_032424               4103 bp    mRNA    linear   PRI 19-SEP-2024
DEFINITION  Homo sapiens Myb/SANT DNA binding domain containing 4 with
            coiled-coils (MSANTD4), transcript variant 1, mRNA.
ACCESSION   NM_032424 XM_370653
VERSION     NM_032424.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 4103)
  AUTHORS   Huttlin,E.L., Bruckner,R.J., Navarrete-Perea,J., Cannon,J.R.,
            Baltier,K., Gebreab,F., Gygi,M.P., Thornock,A., Zarraga,G., Tam,S.,
            Szpyt,J., Gassaway,B.M., Panov,A., Parzen,H., Fu,S., Golbazi,A.,
            Maenpaa,E., Stricker,K., Guha Thakurta,S., Zhang,T., Rad,R.,
            Pan,J., Nusinow,D.P., Paulo,J.A., Schweppe,D.K., Vaites,L.P.,
            Harper,J.W. and Gygi,S.P.
  TITLE     Dual proteome-scale networks reveal cell-specific remodeling of the
            human interactome
  JOURNAL   Cell 184 (11), 3022-3040 (2021)
   PUBMED   33961781
REFERENCE   2  (bases 1 to 4103)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   3  (bases 1 to 4103)
  AUTHORS   Huttlin,E.L., Bruckner,R.J., Paulo,J.A., Cannon,J.R., Ting,L.,
            Baltier,K., Colby,G., Gebreab,F., Gygi,M.P., Parzen,H., Szpyt,J.,
            Tam,S., Zarraga,G., Pontano-Vaites,L., Swarup,S., White,A.E.,
            Schweppe,D.K., Rad,R., Erickson,B.K., Obar,R.A., Guruharsha,K.G.,
            Li,K., Artavanis-Tsakonas,S., Gygi,S.P. and Harper,J.W.
  TITLE     Architecture of the human interactome defines protein communities
            and disease networks
  JOURNAL   Nature 545 (7655), 505-509 (2017)
   PUBMED   28514442
REFERENCE   4  (bases 1 to 4103)
  AUTHORS   Simpson,J.C., Wellenreuther,R., Poustka,A., Pepperkok,R. and
            Wiemann,S.
  TITLE     Systematic subcellular localization of novel proteins identified by
            large-scale cDNA sequencing
  JOURNAL   EMBO Rep 1 (3), 287-292 (2000)
   PUBMED   11256614
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            DA796698.1, AB058729.1, AP000813.4 and AI127319.1.
            
            On Nov 23, 2018 this sequence version replaced NM_032424.2.
            
            Transcript Variant: This variant (1) represents the longest
            transcript. All five variants encode the same protein.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AB058729.1, SRR1803614.13309.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN03267750, SAMN03267764
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000301919.9/ ENSP00000304713.4
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-13                DA796698.1         48-60
            14-816              AB058729.1         1-803
            817-817             AP000813.4         79745-79745         c
            818-968             AB058729.1         805-955
            969-969             AP000813.4         79593-79593         c
            970-1629            AB058729.1         957-1616
            1630-1630           AP000813.4         69038-69038         c
            1631-4015           AB058729.1         1618-4002
            4016-4082           AI127319.1         11-77               c
            4083-4103           AP000813.4         66220-66240         c
FEATURES             Location/Qualifiers
     source          1..4103
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="11"
                     /map="11q22.3"
     gene            1..4103
                     /gene="MSANTD4"
                     /gene_synonym="KIAA1826"
                     /note="Myb/SANT DNA binding domain containing 4 with
                     coiled-coils"
                     /db_xref="GeneID:84437"
                     /db_xref="HGNC:HGNC:29383"
     exon            1..1279
                     /gene="MSANTD4"
                     /gene_synonym="KIAA1826"
                     /inference="alignment:Splign:2.1.0"
     exon            1280..1891
                     /gene="MSANTD4"
                     /gene_synonym="KIAA1826"
                     /inference="alignment:Splign:2.1.0"
     CDS             1430..2467
                     /gene="MSANTD4"
                     /gene_synonym="KIAA1826"
                     /note="Myb/SANT-like DNA-binding domain containing 4 with
                     coiled-coils"
                     /codon_start=1
                     /product="myb/SANT-like DNA-binding domain-containing
                     protein 4"
                     /protein_id="NP_115800.1"
                     /db_xref="CCDS:CCDS31663.1"
                     /db_xref="GeneID:84437"
                     /db_xref="HGNC:HGNC:29383"
                     /translation="MKQLKRKRKSNFSVQETQTLLKEITKRKEVIFSKQLNTTINVMK
                     RMAWEEIAQCVNAVGEGEQRTGTEVKRRYLDWRALMKRKRMKANIKLVGSGFPLPSSD
                     LDDSLTEEIDEKIGFRNDANFDWQNVADFRDAGGSLTEVKVEEEERDPQSPEFEIEEE
                     EEMLSSVIPDSRRENELPDFPHIDEFFTLNSTPSRSAYDEPHLLVNIEKQKLELEKRR
                     LDIEAERLQVEKERLQIEKERLRHLDMEHERLQLEKERLQIEREKLRLQIVNSEKPSL
                     ENELGQGEKSMLQPQDIETEKLKLERERLQLEKDRLQFLKFESEKLQIEKERLQVEKD
                     RLRIQKEGHLQ"
     exon            1892..4103
                     /gene="MSANTD4"
                     /gene_synonym="KIAA1826"
                     /inference="alignment:Splign:2.1.0"
     regulatory      4077..4082
                     /regulatory_class="polyA_signal_sequence"
                     /gene="MSANTD4"
                     /gene_synonym="KIAA1826"
                     /note="hexamer: AATAAA"
     polyA_site      4082
                     /gene="MSANTD4"
                     /gene_synonym="KIAA1826"
                     /note="major polyA site"
ORIGIN      
        1 ctacccccct tggggcgacc gtggggaggt gccgccgggg tcgcaggtga gcggttctat
       61 gctggaggag gcggccaggg aagcggcggc tccgtgacca gtgggtgccc tcgcagtggg
      121 tagggtcccg gaggggtcag cggcaattgg cgcaacgctt gctgccgggt ttggtccaag
      181 ggctgcgacg tagcgggact gcacgctcgg gagaagtgcc acgcgcgtct gtcgcctgac
      241 cggggaggct ggggagggcc caggccacgg aaacaagact gcagaagttt ctgggcactc
      301 agtcgggact ctcatttaat acccagagag aggagatctt ccaggttgcc ccgactccca
      361 ccgggactcc taccagcagc aacctcatca ttgtggccga ggcaggtgcg cgcccctgct
      421 cccctgggtg gccttccggg agcccagtct aactcgattc ttcccagggg ctctttttgg
      481 acggtcccaa aggaggcagc gggagggagg tgaaagatac tttgataacc gtcgacccat
      541 aagtatactt gttatgcacc taccacgagt tttagagaag aacatacttt ttggcaggga
      601 agtgaatccc ctataagaat ataggggagg ggaaagccac actttaaaga gaatttgggt
      661 agggtttgat attgtagatt tgtgatgctt ttcttcttga actgcttaac taatttaccc
      721 tcaaattttt ttgatccgga acttgccgtc tggtttttct cagacttctt aattctgact
      781 tatcatgaag tatctaggaa cttcattctc aagttttagt gcttgtaaaa agttgcctgg
      841 ttatattatg ccattggcag tacatcatct tcacaaggat tacgtaagtg aactacatct
      901 cattcctgtt tccaactagt gaagaacgat tgtgaaatgg gattttagaa aatggctgtt
      961 ctctgtgatt gggcatagaa ggtttgtaag ttttagagac tgcagctgtt gaatcctttc
     1021 tgctaagaga gcgatgacag gcaatagaaa agggatagtg tttgacatct aaaatgacat
     1081 attttcacat tttatgaggt gttatatccc cagcaccaaa aatagtgcct ttcacacagt
     1141 aggagctcag taagtatttt ttgaggaaat tattggggaa tgaatggatg gtagaaaacc
     1201 caagcttctg ttacttggat accggcatat aaaggagagg acaggaagac aaacatttct
     1261 ggaaatggct tttatccagg aattatccag actgccttgc cactagatga atggaagaca
     1321 atgatttgaa ctaagggcca gcaaagaatt atccctggtt tttgtgcttt gcagcattcc
     1381 tcaaattgtt ttcacatctc ttaccataaa aactgcattg aaattgaaaa tgaagcagtt
     1441 gaaaagaaaa aggaaaagca attttagtgt tcaagaaact cagacccttt tgaaagaaat
     1501 tacgaaaagg aaagaagtca ttttttccaa gcagctcaat acaacaatta atgtgatgaa
     1561 gcgaatggct tgggaagaga ttgcacagtg tgtgaatgct gtaggagaag gagaacagag
     1621 gacagggaca gaggtgaaaa gaaggtacct tgactggcga gcacttatga agagaaagag
     1681 gatgaaggcc aacattaagc tggttggttc aggatttccc cttccctcct ctgatttgga
     1741 tgactctctc actgaagaga tagatgaaaa gattggattc cgaaatgatg caaattttga
     1801 ctggcaaaat gtggcagatt tcagggatgc aggtggatcc ttaactgagg tcaaggtgga
     1861 agaggaagaa agggatccgc agagtcctga atttgaaatt gaggaggagg aagaaatgtt
     1921 gtcatccgtc ataccagatt ccaggagaga aaatgaactt cccgatttcc cccacattga
     1981 tgagtttttt acccttaact caacaccatc tagatctgca tatgatgagc ctcatttgct
     2041 cgtaaatatt gagaaacaga aactagagtt ggaaaaacga cgactggata tcgaggccga
     2101 aaggctgcag gtagaaaagg aacgcctaca aatcgagaaa gagaggctgc ggcatttaga
     2161 catggaacat gagcggcttc agctagagaa ggagcggctg cagattgaaa gagaaaagtt
     2221 gaggttacag atagtcaatt cagagaaacc gtccttggaa aatgaacttg gtcaaggaga
     2281 aaaatccatg cttcaaccac aggacataga aacagagaag ttaaaacttg agcgagaacg
     2341 cttgcaactg gaaaaggata ggctgcagtt tttgaagttt gaatctgaga agctgcagat
     2401 tgaaaaggaa cgcttacagg tagagaaaga cagacttcga attcagaaag aaggacactt
     2461 gcagtgattt ttccaggctt ccatttagca aatgtttgaa aactctagat ttttctcata
     2521 tcaggtgata taatgatggt tgctggatta gctgtggttt cttgtctaat gtcagtgttc
     2581 agtaggaaaa agttatatgt ggataactgt atgcctaagt agtatataaa agctgtgccc
     2641 tagcgtaaac agtatagcag aaacttactg tgctggactc tttaccttat aatattacat
     2701 agagtcttgt attgtctgtg tacccagagt ttacaattat gtccatataa aattctagcc
     2761 cagaagttct catctggggt agattttggc cttcagaaga ccaatttggt gatgtctgga
     2821 gacatgttgg gttgtcaaaa ctggggtggg gaaaaggttg ctactgtgca atgcatacct
     2881 cctcaacacc cccccacact cagtaaagaa ttttccaacc caaaatatca ttagtcctga
     2941 ggttgagaaa ccctgtccta gcctaactgt gtacctctat agctatgttt tatagtttta
     3001 gaatattaaa acctcagata tttatgtggg taggtactta aatggccaaa aactttaact
     3061 atgaaatgtt actgtgtagt atattgaata taggaagtga tgaagattat aggtatttta
     3121 ttcccatgtt tccatctata aatagccttc tcagattcag aaaacaatac agagaacatc
     3181 agaaattttc taaaatgggt cactttgaaa agaattcttt ttctcactat taatgcttta
     3241 gaagcaagac gcaattttaa agctttagtt ccttttcttt cagtcattgt cttagtttgg
     3301 gtacaaaaat gtcatttcag taatgtactg aaatcttata agtgaatagt tgaagctagt
     3361 aaaaatgata ccagtataaa aatggtactt gtagtccatg agcttgaacc caatgactga
     3421 ttgtttgact tttaaaataa gtaatagcag ccatttggga gtagggggta ggtggggaag
     3481 atgtactccg tatcaaataa taatgatgtt gaaataatga tagtaggtat gtattatgga
     3541 ttggagaagc acttattaca ctatctaacc taatatgtag aacaattctt gagagttgta
     3601 tctgtcgtta tttctgaatg tgaagctcag agaagtgaca cagagtaaat ggctgatctt
     3661 ctatattgta gtatattttg tccttccctc ttccctgagg aacaaagcac gtatctttag
     3721 tctctttgat atttattctg agaccaaggg cttgcttgac ctgatgattt tccttcagct
     3781 ctctgaaggt gctttttcca caatccaagt gattctgata cacactaaag ttgagaatca
     3841 ctgcactaga tcactttgtg ttttctgatt ttcaaggttg atacgtagct ttaatacagc
     3901 tcttctgttg acagttatta ctttaatttt gcatttgttc cttgtaagaa tggctggaaa
     3961 ctgtgtgttg acatttgagg atgggtatgc aaggaaaaaa tatacttctg tttacttact
     4021 ctgactttga aatagtgtta tttttctata tctgaaataa atgcttctac catagaaata
     4081 aatttgccta tactatctga gaa
//
