LOCUS       NM_001012417             949 bp    mRNA    linear   PRI 03-AUG-2024
DEFINITION  Homo sapiens membrane spanning 4-domains A13 (MS4A13), transcript
            variant 1, mRNA.
ACCESSION   NM_001012417
VERSION     NM_001012417.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 949)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   2  (bases 1 to 949)
  AUTHORS   Yu,B., Zheng,Y., Alexander,D., Manolio,T.A., Alonso,A.,
            Nettleton,J.A. and Boerwinkle,E.
  TITLE     Genome-wide association study of a heart failure related
            metabolomic profile among African Americans in the Atherosclerosis
            Risk in Communities (ARIC) study
  JOURNAL   Genet Epidemiol 37 (8), 840-845 (2013)
   PUBMED   23934736
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AP001034.5 and AY324188.1.
            
            On May 17, 2019 this sequence version replaced NM_001012417.2.
            
            Transcript Variant: This variant (1) encodes the longest isoform
            (1).
            
            ##Evidence-Data-START##
            Transcript exon combination :: AY324188.1, BC140799.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1968968, SAMEA2148874
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000378186.7/ ENSP00000367428.2
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-21                AP001034.5         108433-108453
            22-97               AY324188.1         1-76
            98-99               AP001034.5         108530-108531
            100-648             AY324188.1         79-627
            649-649             AP001034.5         118366-118366
            650-949             AY324188.1         629-928
FEATURES             Location/Qualifiers
     source          1..949
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="11"
                     /map="11q12.2"
     gene            1..949
                     /gene="MS4A13"
                     /note="membrane spanning 4-domains A13"
                     /db_xref="GeneID:503497"
                     /db_xref="HGNC:HGNC:16674"
     exon            1..216
                     /gene="MS4A13"
                     /inference="alignment:Splign:2.1.0"
     exon            217..332
                     /gene="MS4A13"
                     /inference="alignment:Splign:2.1.0"
     exon            333..473
                     /gene="MS4A13"
                     /inference="alignment:Splign:2.1.0"
     CDS             345..803
                     /gene="MS4A13"
                     /note="isoform 1 is encoded by transcript variant 1;
                     testis-expressed transmembrane-4 protein; testis-expressed
                     transmembrane protein 4; membrane-spanning 4-domains
                     subfamily A member 13"
                     /codon_start=1
                     /product="membrane-spanning 4-domains subfamily A member
                     13 isoform 1"
                     /protein_id="NP_001012417.2"
                     /db_xref="CCDS:CCDS31571.1"
                     /db_xref="GeneID:503497"
                     /db_xref="HGNC:HGNC:16674"
                     /translation="MIGIFHIFMWYFLLVLYMGQIKGAFGTYEPVTYKTGCTLWGIFF
                     IIAGVFLIRVTKYPTRSGIISTLIINIICIITTITAVTLTIIELSHFNSVSYRNYGQA
                     KLGREVSRILLFFYGLEFSIALTHSIYSCSNLFRRQNDLTSVTEEAESTP"
     exon            474..530
                     /gene="MS4A13"
                     /inference="alignment:Splign:2.1.0"
     exon            531..650
                     /gene="MS4A13"
                     /inference="alignment:Splign:2.1.0"
     exon            651..746
                     /gene="MS4A13"
                     /inference="alignment:Splign:2.1.0"
     exon            747..949
                     /gene="MS4A13"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gtcactccct gaggagcctg agagccggcc gggtgctggg ctcctggcta tccctgtgat
       61 ggtagctcag cgagatctgg ggacctggcg ctgagcgcgt tgccagccgg gatcttcctc
      121 ttcatctagg cctgggcgct ggcgtgagaa ctcggactgg gtcctggacg agcgcccccc
      181 gaaactcctt ggaaccttga acaagtaaaa tgcaggaagt ttgctaataa agacatcacc
      241 aaaggttaaa gagaaaatca tctagaggaa atgctggcag tatggcatgt gttctttaac
      301 aaatctctac agcagattct ctcgttttag ggactatcca gattatgatt ggcatctttc
      361 acattttcat gtggtacttt ctattggttt tgtatatggg acaaattaaa ggagcctttg
      421 gaacgtatga acctgtaact tacaaaacag gatgtacttt atggggaatt ttttttatca
      481 ttgcaggagt cttcctaata agagtaacaa agtatccgac tcgatctgga attataagta
      541 ctttaatcat aaacatcatc tgcataatta ctacaattac tgcagtaact ctaacaataa
      601 tagagttgtc tcattttaat tctgtgtcat acaggaatta tggacaagca aaacttggga
      661 gggaagtatc acgtatttta ctgttcttct acggtttgga attttctatt gcacttacac
      721 actcaatata cagctgttcc aatttgtttc gaagacaaaa tgatcttaca tctgttactg
      781 aggaagctga gagcactcct taaaaaccct agaaatatga gaattttgct gttgctgatg
      841 cctggtgtgg gtcctaatga tatctctgta taacaaagca gttacgaagc ctacagattt
      901 tgtgcaaaat aaaatacaaa caaggtgaat ttttctcctc attcaaaaa
//
