LOCUS       NM_001100878            3265 bp    mRNA    linear   PRI 04-APR-2024
DEFINITION  Homo sapiens maestro heat like repeat family member 6 (MROH6),
            mRNA.
ACCESSION   NM_001100878 XM_925979 XM_937463
VERSION     NM_001100878.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 3265)
  AUTHORS   Bussow,K., Cahill,D., Nietfeld,W., Bancroft,D., Scherzinger,E.,
            Lehrach,H. and Walter,G.
  TITLE     A method for global protein expression and antibody screening on
            high-density filters of an arrayed cDNA library
  JOURNAL   Nucleic Acids Res 26 (21), 5007-5008 (1998)
   PUBMED   9776767
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC067930.7, BX341537.2, BM148864.1, CD579780.2, AL040647.1,
            DN831781.1, DB003146.1 and BC029031.1.
            
            On Nov 23, 2018 this sequence version replaced NM_001100878.1.
            
            ##Evidence-Data-START##
            RNAseq introns :: mixed sample support SAMEA1965299, SAMEA1966682
                              [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000398882.8/ ENSP00000381857.3
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-14                AC067930.7         110924-110937       c
            15-182              BX341537.2         1-168
            183-249             BM148864.1         183-249
            250-683             BX341537.2         235-668
            684-793             CD579780.2         240-349
            794-1101            AL040647.1         85-392
            1102-1587           DN831781.1         37-522
            1588-1854           DB003146.1         222-488
            1855-1912           BC029031.1         511-568
            1913-1913           AC067930.7         105963-105963       c
            1914-2001           BC029031.1         570-657
            2002-3265           AC067930.7         104357-105620       c
FEATURES             Location/Qualifiers
     source          1..3265
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="8"
                     /map="8q24.3"
     gene            1..3265
                     /gene="MROH6"
                     /gene_synonym="C8orf73"
                     /note="maestro heat like repeat family member 6"
                     /db_xref="GeneID:642475"
                     /db_xref="HGNC:HGNC:27814"
     exon            1..352
                     /gene="MROH6"
                     /gene_synonym="C8orf73"
                     /inference="alignment:Splign:2.1.0"
     CDS             59..2218
                     /gene="MROH6"
                     /gene_synonym="C8orf73"
                     /codon_start=1
                     /product="maestro heat-like repeat-containing protein
                     family member 6"
                     /protein_id="NP_001094348.1"
                     /db_xref="CCDS:CCDS47928.1"
                     /db_xref="GeneID:642475"
                     /db_xref="HGNC:HGNC:27814"
                     /translation="MAGGVWGRSRAREAPVGALTLTALTEGIRARQGQPQGPPSAGPQ
                     PKSWEVKPEAEPQTQALTAPSEAEPGRGATVPEAGSEPCSLNSALEPAPEGPHQVPQS
                     SWEEGVLADLALYTAACLEEAGFAGTQATVLTLSSALEARGERLEDQVHALVRGLLAQ
                     VPSLAEGRPWRAALRVLSALALEHARDVVCALLPRSLPADRVAAELWRSLSRNQRVNG
                     QVLVQLLWALKGASGPEPQALAATRALGEMLAVSGCVGATRGFYPHLLLALVTQLHKL
                     ARSPCSPDMPKIWVLSHRGPPHSHASCAVEALKALLTGDGGRMVVTCMEQAGGWRRLV
                     GAHTHLEGVLLLASAMVAHADHHLRGLFADLLPRLRSADDPQRLTAMAFFTGLLQSRP
                     TARLLREEVILERLLTWQGDPEPTVRWLGLLGLGHLALNRRKVRHVSTLLPALLGALG
                     EGDARLVGAALGALRRLLLRPRAPVRLLSAELGPRLPPLLDDTRDSIRASAVGLLGTL
                     VRRGRGGLRLGLRGPLRKLVLQSLVPLLLRLHDPSRDAAESSEWTLARCDHAFCWGLL
                     EELVTVAHYDSPEALSHLCCRLVQRYPGHVPNFLSQTQGYLRSPQDPLRRAAAVLIGF
                     LVHHASPGCVNQDLLDSLFQDLGRLQSDPKPAVAAAAHVSAQQVAMLARARGCPRGPR
                     LLRIAPRPARPPPVFADSPFQRRSVAGRWGCSGPRRA"
     exon            353..505
                     /gene="MROH6"
                     /gene_synonym="C8orf73"
                     /inference="alignment:Splign:2.1.0"
     exon            506..660
                     /gene="MROH6"
                     /gene_synonym="C8orf73"
                     /inference="alignment:Splign:2.1.0"
     exon            661..778
                     /gene="MROH6"
                     /gene_synonym="C8orf73"
                     /inference="alignment:Splign:2.1.0"
     exon            779..963
                     /gene="MROH6"
                     /gene_synonym="C8orf73"
                     /inference="alignment:Splign:2.1.0"
     exon            964..1101
                     /gene="MROH6"
                     /gene_synonym="C8orf73"
                     /inference="alignment:Splign:2.1.0"
     exon            1102..1216
                     /gene="MROH6"
                     /gene_synonym="C8orf73"
                     /inference="alignment:Splign:2.1.0"
     exon            1217..1360
                     /gene="MROH6"
                     /gene_synonym="C8orf73"
                     /inference="alignment:Splign:2.1.0"
     exon            1361..1534
                     /gene="MROH6"
                     /gene_synonym="C8orf73"
                     /inference="alignment:Splign:2.1.0"
     exon            1535..1702
                     /gene="MROH6"
                     /gene_synonym="C8orf73"
                     /inference="alignment:Splign:2.1.0"
     exon            1703..1822
                     /gene="MROH6"
                     /gene_synonym="C8orf73"
                     /inference="alignment:Splign:2.1.0"
     exon            1823..1925
                     /gene="MROH6"
                     /gene_synonym="C8orf73"
                     /inference="alignment:Splign:2.1.0"
     exon            1926..1991
                     /gene="MROH6"
                     /gene_synonym="C8orf73"
                     /inference="alignment:Splign:2.1.0"
     exon            1992..3265
                     /gene="MROH6"
                     /gene_synonym="C8orf73"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3244..3249
                     /regulatory_class="polyA_signal_sequence"
                     /gene="MROH6"
                     /gene_synonym="C8orf73"
                     /note="hexamer: AATAAA"
     polyA_site      3265
                     /gene="MROH6"
                     /gene_synonym="C8orf73"
                     /note="major polyA site"
ORIGIN      
        1 agtcctgggc acaacttcgc aggaggagca gcggcaggtg ctgcaggcaa gggccgccat
       61 ggctgggggt gtgtggggcc ggagccgggc ccgggaggct cccgtggggg ctctaaccct
      121 gacagcactg actgaaggaa tccgggccag gcaggggcag ccccagggac ccccttccgc
      181 aggccctcag cccaagtcct gggaggtcaa acctgaggct gagccacaga cccaggcact
      241 caccgccccc tctgaggcag agcctggacg tggggccacc gtccctgaag ctggcagcga
      301 gccctgctcc ctcaacagtg ccctggaacc agcccctgag gggccccacc aggttcccca
      361 gagttcctgg gaggagggag ttcttgccga cctcgcgttg tacacggctg cctgcctgga
      421 ggaggctggc tttgcaggga cccaggcgac agtgctcacc ctgtcctcag ccctggaggc
      481 ccggggcgag cggttggagg accaggtgca tgctctggtg cgtgggctgc tggcgcaggt
      541 gcccagccta gcggagggga ggccctggag ggcggccctg cgagtgctga gcgcactggc
      601 cctggagcat gcgcgggacg tggtgtgtgc gctgctaccc cgctctctgc ccgccgatcg
      661 ggtagcagcc gagctctggc gcagcctaag ccgtaaccag cgtgtaaatg ggcaggtgct
      721 ggtgcaactg ctgtgggcgc tgaagggtgc ttcggggccg gagccccagg cactggcggc
      781 cacacgtgct cttggggaga tgctggctgt ttcgggctgc gtgggagcca cgaggggctt
      841 ctacccacat ctgctgcttg cgctggtcac acagctgcac aagctggccc gcagcccgtg
      901 ctcccccgac atgcccaaga tttgggttct gtcccaccga gggccaccac atagccatgc
      961 cagctgtgct gtggaggcct tgaaggcgct gctcaccggg gatggaggcc gcatggtggt
     1021 cacgtgcatg gagcaggcag gaggctggag gaggctggtg ggagcccaca cccacctgga
     1081 gggcgtcctg ctgctggcca gtgctatggt ggcacatgcc gaccaccacc tgcgaggcct
     1141 cttcgcagac ttgctccctc ggcttcgcag cgcggacgac ccgcagcgtc tcacggctat
     1201 ggccttcttc acagggctgt tgcagagccg gcccaccgca cggctcctgc gggaggaggt
     1261 catcctggag cgactcctca cctggcaggg agaccccgaa cccactgtgc gctggttggg
     1321 cctgctgggc ctgggccacc tcgcgctgaa tcgcaggaag gtgcggcacg tgagcacgct
     1381 gctgccggcg ctcctgggcg cactgggcga aggcgacgcg cggctcgtgg gtgcagcgct
     1441 gggcgccctg aggaggctcc tgctgcggcc ccgggcgcct gtgcggctcc tgagcgcgga
     1501 gctgggaccg cgcctccctc cgctactgga cgacacacgg gactcaatcc gcgcctcggc
     1561 cgtcgggctc cttgggactc tggtgcgccg gggccggggc gggctccggc tggggctccg
     1621 cggccccctg cggaagctgg tgctgcagag tctcgtgccg ctgctgctgc gcctgcatga
     1681 ccccagcagg gacgctgctg agagctcaga gtggaccctg gcccgctgtg accacgcctt
     1741 ttgctggggc ctgctggagg agttggtcac cgtggcccac tatgacagcc ccgaggccct
     1801 gagccacctc tgctgccgcc tggttcagcg atacccaggc cacgtgccca acttcctgag
     1861 ccagacccag ggctacctgc ggagtccaca ggaccccctg cgccgggcag ccgccgtgct
     1921 tataggcttc cttgtccacc acgccagccc cggctgtgtc aaccaggacc tgctggactc
     1981 cctgttccag gacctagggc gactgcagag cgaccccaag ccggctgtgg ccgcggcagc
     2041 gcacgtgtcc gctcagcagg tggcgatgct ggcccgtgcc cggggctgcc cccgcgggcc
     2101 ccgccttctc cgcatcgccc cgcgccccgc ccggccccca ccagtcttcg ccgacagccc
     2161 cttccagcgc cggagcgtcg cgggccgctg gggctgctcc ggaccccgcc gagcctgagg
     2221 ctcggggctg gggcccgagg gccagggtcc gactcgggca ccccacgcgc atagcagcct
     2281 gtccccgccc tgacggaggg gctccctggg cctggtgctg gacgccaatg ccctccccca
     2341 ccccccaccc ccgtgacccc tcttcaggca cccaccaccc tgatggtgac agagggggac
     2401 agccagcacc catctgtccc cgtcagggct cttgttctca cagccccctg gagcatgccc
     2461 catgccccaa ccttgggcct ggctcctggc ccagatggca cctggcctct tgagtctgct
     2521 gggggacccc aaagttggtg gtcccatagc ctgccctcct gggtctccac ctcatgcctg
     2581 gacaggacgc tgtggcctgt ccgggccttg gccagccctg cagctgcacc cccgatcctc
     2641 atccctcacc ccattccctg ccagcatcct aaggctcctg gcgggcatcc tctctgctca
     2701 aaattattga cctgtctccc ggccacacct gctgtgccct ctcagccagg ccatcatcac
     2761 cccctgttca ttatgtcagg cctcatggga gcctggcctt ctccagaagc tggccccggc
     2821 gtcctcccaa gctggaccac gtaggcccca gatcacacct gggggtccag atgtaggggt
     2881 cctgtgtgca cgcccaatca gaccgagcac ttgtgacact accccaacac ctctcccagg
     2941 gctgaatgag gaacgcgcca ctggacacat gaggaagagg ctgctctggg agctactgat
     3001 gctgtgacct cacctctctg gctttgggcg gcaggtccct gcacctagga tgcctgcctg
     3061 gaaatgtcct tgcattcgtg gcctccttca cagcctcctc ctcagagaag cctctgcgag
     3121 tgcacaggga gtgtgtgcag ccttgtgaag ggctgggacc acttgcccag actggggccc
     3181 ctcaggcaca ggcgtggggt cctactgacc tgtctcccca gctcccacac agaaagcatc
     3241 taaaataaac acacgtggat ggaaa
//
