LOCUS       NM_173489               5280 bp    mRNA    linear   PRI 23-AUG-2024
DEFINITION  Homo sapiens maestro heat like repeat family member 2B (MROH2B),
            mRNA.
ACCESSION   NM_173489
VERSION     NM_173489.5
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 5280)
  AUTHORS   Stanger,S.J., Law,E.A., Jamsai,D., O'Bryan,M.K., Nixon,B.,
            McLaughlin,E.A., Aitken,R.J. and Roman,S.D.
  TITLE     A novel germ cell protein, SPIF (sperm PKA interacting factor), is
            essential for the formation of a PKA/TCP11 complex that undergoes
            conformational and phosphorylation changes upon capacitation
  JOURNAL   FASEB J 30 (8), 2777-2791 (2016)
   PUBMED   27105888
REFERENCE   2  (bases 1 to 5280)
  AUTHORS   Kallio,S.P., Jakkula,E., Purcell,S., Suvela,M., Koivisto,K.,
            Tienari,P.J., Elovaara,I., Pirttila,T., Reunanen,M., Bronnikov,D.,
            Viander,M., Meri,S., Hillert,J., Lundmark,F., Harbo,H.F.,
            Lorentzen,A.R., De Jager,P.L., Daly,M.J., Hafler,D.A., Palotie,A.,
            Peltonen,L. and Saarela,J.
  TITLE     Use of a genetic isolate to identify rare disease variants: C7 on
            5p associated with MS
  JOURNAL   Hum Mol Genet 18 (9), 1670-1683 (2009)
   PUBMED   19221116
  REMARK    GeneRIF: Observational study of gene-disease association. (HuGE
            Navigator)
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BF979306.1, BC034600.1, AC114967.2, BC052962.1, CR749346.1,
            BC044937.1 and AK128183.1.
            
            On Nov 24, 2018 this sequence version replaced NM_173489.4.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC052962.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA1968540,
                                           SAMEA1968968 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000399564.5/ ENSP00000382476.4
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-36                BF979306.1         6-41
            37-520              BC034600.1         1-484
            521-521             AC114967.2         163068-163068       c
            522-1060            BC034600.1         486-1024
            1061-1061           AC114967.2         154932-154932       c
            1062-1830           BC052962.1         1023-1791
            1831-1975           CR749346.1         732-876
            1976-1984           BC044937.1         310-318
            1985-2352           AK128183.1         451-818
            2353-2432           BC044937.1         825-904
            2433-4025           BC052962.1         2394-3986
            4026-4026           BC044937.1         2498-2498
            4027-5279           AK128183.1         2493-3745
            5280-5280           BC044937.1         3932-3932
FEATURES             Location/Qualifiers
     source          1..5280
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="5"
                     /map="5p13.1"
     gene            1..5280
                     /gene="MROH2B"
                     /gene_synonym="HEATR7B2; SPIF"
                     /note="maestro heat like repeat family member 2B"
                     /db_xref="GeneID:133558"
                     /db_xref="HGNC:HGNC:26857"
                     /db_xref="MIM:620930"
     exon            1..518
                     /gene="MROH2B"
                     /gene_synonym="HEATR7B2; SPIF"
                     /inference="alignment:Splign:2.1.0"
     CDS             491..5248
                     /gene="MROH2B"
                     /gene_synonym="HEATR7B2; SPIF"
                     /note="HEAT repeat family member B2; HEAT
                     repeat-containing protein 7B2; HEAT repeat family member
                     7B2; sperm PKA-interacting factor"
                     /codon_start=1
                     /product="maestro heat-like repeat-containing protein
                     family member 2B"
                     /protein_id="NP_775760.3"
                     /db_xref="CCDS:CCDS47202.1"
                     /db_xref="GeneID:133558"
                     /db_xref="HGNC:HGNC:26857"
                     /db_xref="MIM:620930"
                     /translation="MTLSTEESIEMFGDINLTLGMLNKEDIVNKEDIYSHLTSVIQNT
                     DILDDAIVQRLIYYASKDMRDNNMLREIRMLAGEVLVSLAAHDFNSVMYEVQSNFRIL
                     ELPDEFVVLALAELATSYVSQSIPFMMMTLLTMQTMLRLAEDERMKGTFCIALEKFSK
                     AIYKYVNHWRDFPYPRLDANRLSDKIFMLFWYIMEKWAPLASPMQTLSIVKAHGPTVS
                     LLLHREDFRGYALGQVPWLLNQYKDKEIDFHVTQSLKQILTAAVLYDIGLPRSLRRSI
                     FINLLQQICRAPEPPVKENEMKASSCFLILAHSNPGELMEFFDEQVRSNNEAIRVGIL
                     TLLRLAVNADEPRLRDHIISIERTVKIVMGDLSTKVRNSVLLLIQTMCEKSYIEAREG
                     WPLIDYVFSQFATLNRNLEKPVKTNFHENEKEEESVRETSLEVLKTLDPLVIGMPQVL
                     WPRILTFVVPAEYTEALEPLFSIIRILIMAEEKKQHSAKESTALVVSTGAVKLPSPQQ
                     LLARLLVISMPASLGELRGAGAIGLLKILPEIIHPKLVDLWKTRLPELLQPLEGKNIS
                     TVLWETMLLQLLKESLWKISDVAWTIQLTQDFKQQMGSYSNNSTEKKFLWKALGTTLA
                     CCQDSDFVNSQIKEFLTAPNQLGDQRQGITSILGYCAENHLDIVLKVLKTFQNQEKFF
                     MNRCKSLFSGKKSLTKTDVMVIYGAVALHAPKKQLLSRLNQDIISQVLSLHGQCSQVL
                     GMSVMNKDMDLQMSFTRSITEIGIAVQDAEDQGFQFSYKEMLIGYMLDFIRDEPLDSL
                     ASPIRWKALIAIRYLSKLKPQLSLQDHLNILEENIRRLLPLPPLENLKSEGQTDKDKE
                     HIQFLYERSMDALGKLLKTMMWDNVNAEDCQEMFNLLQMWLVSQKEWERERAFQITAK
                     VLTNDIEAPENFKIGSLLGLLAPHSCDTLPTIRQAAASSTIGLFYIKGIHLEVERLQG
                     LQEGLESDDVQVQIKISSKIAKIVSKFIPNEEILMFLEEMLDGLESLNPTCTKACGIW
                     MITVLKQQGAALEDQLLEILGTIYHHMPVLRQKEESFQFILEAISQIASFHMDTVVVN
                     LLQKPLPFDRDTKTLWKALAEKPASSGKLLQALIDKLETELEDDIARVEAISVACAMY
                     EVISMGTSVTGLYPELFTLLLKLVSCTLGQKMLTCPWSHRRHVMQQGEQQQIPDPCRL
                     STATLKCLQAQAMREGLAKESDEGDNLWTLLSSPSTHHIGVCSLARSMAVWQHGVILD
                     IMEQLLSSLTSSSENYRITGAAFFSELMKEPILWKHGNLRNVLILMDQSAWDSNATLR
                     QMAIRGLGNTASGAPHKVKKHKQLMLESIIRGLYHLARTEVVCESLKALKKILELLTD
                     RDVSFYFKEIVLQTRTFFEDEQDDVRLTAIFLFEDLAPLTGRRWKIFFAEEIKKSLIS
                     FLLHLWDPNPKIGVACRDVLMVCIPFLGLQELYGVLDRLLDQDLPRARDFYRQFCVKL
                     AKKNQEILWILHTHSFTFFTSTWEVIRSAAVKLTDAVVLNLTSQYVELLDREQLTTRL
                     QALRQDPCISVQRAAEAALQTLLRRCKETSIPL"
     exon            519..580
                     /gene="MROH2B"
                     /gene_synonym="HEATR7B2; SPIF"
                     /inference="alignment:Splign:2.1.0"
     exon            581..691
                     /gene="MROH2B"
                     /gene_synonym="HEATR7B2; SPIF"
                     /inference="alignment:Splign:2.1.0"
     exon            692..851
                     /gene="MROH2B"
                     /gene_synonym="HEATR7B2; SPIF"
                     /inference="alignment:Splign:2.1.0"
     exon            852..950
                     /gene="MROH2B"
                     /gene_synonym="HEATR7B2; SPIF"
                     /inference="alignment:Splign:2.1.0"
     exon            951..1105
                     /gene="MROH2B"
                     /gene_synonym="HEATR7B2; SPIF"
                     /inference="alignment:Splign:2.1.0"
     exon            1106..1246
                     /gene="MROH2B"
                     /gene_synonym="HEATR7B2; SPIF"
                     /inference="alignment:Splign:2.1.0"
     exon            1247..1339
                     /gene="MROH2B"
                     /gene_synonym="HEATR7B2; SPIF"
                     /inference="alignment:Splign:2.1.0"
     exon            1340..1409
                     /gene="MROH2B"
                     /gene_synonym="HEATR7B2; SPIF"
                     /inference="alignment:Splign:2.1.0"
     exon            1410..1523
                     /gene="MROH2B"
                     /gene_synonym="HEATR7B2; SPIF"
                     /inference="alignment:Splign:2.1.0"
     exon            1524..1597
                     /gene="MROH2B"
                     /gene_synonym="HEATR7B2; SPIF"
                     /inference="alignment:Splign:2.1.0"
     exon            1598..1720
                     /gene="MROH2B"
                     /gene_synonym="HEATR7B2; SPIF"
                     /inference="alignment:Splign:2.1.0"
     exon            1721..1834
                     /gene="MROH2B"
                     /gene_synonym="HEATR7B2; SPIF"
                     /inference="alignment:Splign:2.1.0"
     exon            1835..1991
                     /gene="MROH2B"
                     /gene_synonym="HEATR7B2; SPIF"
                     /inference="alignment:Splign:2.1.0"
     exon            1992..2032
                     /gene="MROH2B"
                     /gene_synonym="HEATR7B2; SPIF"
                     /inference="alignment:Splign:2.1.0"
     exon            2033..2174
                     /gene="MROH2B"
                     /gene_synonym="HEATR7B2; SPIF"
                     /inference="alignment:Splign:2.1.0"
     exon            2175..2218
                     /gene="MROH2B"
                     /gene_synonym="HEATR7B2; SPIF"
                     /inference="alignment:Splign:2.1.0"
     exon            2219..2326
                     /gene="MROH2B"
                     /gene_synonym="HEATR7B2; SPIF"
                     /inference="alignment:Splign:2.1.0"
     exon            2327..2443
                     /gene="MROH2B"
                     /gene_synonym="HEATR7B2; SPIF"
                     /inference="alignment:Splign:2.1.0"
     exon            2444..2551
                     /gene="MROH2B"
                     /gene_synonym="HEATR7B2; SPIF"
                     /inference="alignment:Splign:2.1.0"
     exon            2552..2704
                     /gene="MROH2B"
                     /gene_synonym="HEATR7B2; SPIF"
                     /inference="alignment:Splign:2.1.0"
     exon            2705..2731
                     /gene="MROH2B"
                     /gene_synonym="HEATR7B2; SPIF"
                     /inference="alignment:Splign:2.1.0"
     exon            2732..2851
                     /gene="MROH2B"
                     /gene_synonym="HEATR7B2; SPIF"
                     /inference="alignment:Splign:2.1.0"
     exon            2852..2931
                     /gene="MROH2B"
                     /gene_synonym="HEATR7B2; SPIF"
                     /inference="alignment:Splign:2.1.0"
     exon            2932..3067
                     /gene="MROH2B"
                     /gene_synonym="HEATR7B2; SPIF"
                     /inference="alignment:Splign:2.1.0"
     exon            3068..3163
                     /gene="MROH2B"
                     /gene_synonym="HEATR7B2; SPIF"
                     /inference="alignment:Splign:2.1.0"
     exon            3164..3253
                     /gene="MROH2B"
                     /gene_synonym="HEATR7B2; SPIF"
                     /inference="alignment:Splign:2.1.0"
     exon            3254..3374
                     /gene="MROH2B"
                     /gene_synonym="HEATR7B2; SPIF"
                     /inference="alignment:Splign:2.1.0"
     exon            3375..3472
                     /gene="MROH2B"
                     /gene_synonym="HEATR7B2; SPIF"
                     /inference="alignment:Splign:2.1.0"
     exon            3473..3625
                     /gene="MROH2B"
                     /gene_synonym="HEATR7B2; SPIF"
                     /inference="alignment:Splign:2.1.0"
     exon            3626..3783
                     /gene="MROH2B"
                     /gene_synonym="HEATR7B2; SPIF"
                     /inference="alignment:Splign:2.1.0"
     exon            3784..3910
                     /gene="MROH2B"
                     /gene_synonym="HEATR7B2; SPIF"
                     /inference="alignment:Splign:2.1.0"
     exon            3911..4098
                     /gene="MROH2B"
                     /gene_synonym="HEATR7B2; SPIF"
                     /inference="alignment:Splign:2.1.0"
     exon            4099..4239
                     /gene="MROH2B"
                     /gene_synonym="HEATR7B2; SPIF"
                     /inference="alignment:Splign:2.1.0"
     exon            4240..4354
                     /gene="MROH2B"
                     /gene_synonym="HEATR7B2; SPIF"
                     /inference="alignment:Splign:2.1.0"
     exon            4355..4501
                     /gene="MROH2B"
                     /gene_synonym="HEATR7B2; SPIF"
                     /inference="alignment:Splign:2.1.0"
     exon            4502..4684
                     /gene="MROH2B"
                     /gene_synonym="HEATR7B2; SPIF"
                     /inference="alignment:Splign:2.1.0"
     exon            4685..4840
                     /gene="MROH2B"
                     /gene_synonym="HEATR7B2; SPIF"
                     /inference="alignment:Splign:2.1.0"
     exon            4841..4972
                     /gene="MROH2B"
                     /gene_synonym="HEATR7B2; SPIF"
                     /inference="alignment:Splign:2.1.0"
     exon            4973..5075
                     /gene="MROH2B"
                     /gene_synonym="HEATR7B2; SPIF"
                     /inference="alignment:Splign:2.1.0"
     exon            5076..5141
                     /gene="MROH2B"
                     /gene_synonym="HEATR7B2; SPIF"
                     /inference="alignment:Splign:2.1.0"
     exon            5142..5280
                     /gene="MROH2B"
                     /gene_synonym="HEATR7B2; SPIF"
                     /inference="alignment:Splign:2.1.0"
     regulatory      5259..5264
                     /regulatory_class="polyA_signal_sequence"
                     /gene="MROH2B"
                     /gene_synonym="HEATR7B2; SPIF"
                     /note="hexamer: AATAAA"
     polyA_site      5280
                     /gene="MROH2B"
                     /gene_synonym="HEATR7B2; SPIF"
                     /note="major polyA site"
ORIGIN      
        1 agttcatatg actgattttc actaagtgta acaatcaacg agttcaccat aaagcctttc
       61 ccaacatcag gacagtaaag caactactga aaaccattcc tgaatttgtg atcaatggac
      121 tcaagtttag ggagaggagc acctttggtc tgcaacaatg gtttgaatcc cagtctctaa
      181 ttacttcttt cccaaatact ctggtcacca aagggacaat atttggtgag atgcagccat
      241 tttgttggtt agcaggagtt cagacgcaag acaatgtcat agtggtagaa tacagtatca
      301 acttcaacag caagcccatc tctggaagct cccagaccat tgtgccaatc aagtggagga
      361 ggcactttca tttagagagg cttatgtgaa ccttatatga gaaacttgcc aacctgcctc
      421 tttgattttt tagccttact atttctaata cttaggtgct atcttttaga gaccctgaaa
      481 cagccaagac atgacactta gtacagagga atccatagag atgtttgggg atattaacct
      541 cactcttggc atgctgaaca aggaagatat tgttaacaag gaagacattt acagtcatct
      601 cacttctgtt attcagaata ctgacatctt ggatgatgca attgtccaac gattgattta
      661 ttatgcttct aaggatatga gagacaacaa tatgctcaga gaaatcagaa tgctagctgg
      721 tgaggttttg gtgtctcttg ctgcacatga tttcaactct gtgatgtatg aagtacaaag
      781 taacttcagg atcttagagc taccagatga attcgttgtg cttgccctgg ctgaattggc
      841 aaccagctat gtgtcccaga gtattccttt catgatgatg accctgctca ccatgcaaac
      901 catgctcagg ctggccgagg atgaaaggat gaaggggact ttctgtattg cccttgagaa
      961 attcagcaaa gccatttaca aatatgtcaa ccactggaga gattttccct accccagact
     1021 ggatgccaac cgactgtctg acaagatctt catgctgttc tggtatataa tggagaagtg
     1081 ggcccctttg gcctcaccca tgcagacttt gagcatcgtt aaggcccacg ggcccacggt
     1141 gagcttgctg ctgcatcggg aagacttccg tggatacgcc ctgggccagg tgccctggct
     1201 cctgaaccag tataaagaca aagagattga tttccatgtc actcagagcc taaaacaaat
     1261 actgactgca gcagttcttt atgacattgg ccttccaagg agcttgagaa gatccatctt
     1321 tatcaattta ctccagcaga tctgcagagc tccagagcct ccagtaaagg aaaatgaaat
     1381 gaaagcttca agctgttttc tcattctagc ccattccaat cctggagagc tgatggaatt
     1441 ttttgatgaa caagtaagaa gtaataatga agccattcga gtgggaatct tgactttgtt
     1501 aagattggct gtcaatgctg atgagcccag gttgagggat cacatcattt caatagaaag
     1561 aacagtcaaa atcgtcatgg gtgatctcag tacaaaagta agaaattctg ttcttctcct
     1621 catccaaacc atgtgtgaaa agtcctatat tgaagctcgg gaaggatggc cattgattga
     1681 ttatgtcttc tcccagtttg caacgttgaa caggaatctg gagaaaccag tgaaaactaa
     1741 ctttcatgag aatgaaaagg aagaggaatc tgtccgagaa acaagccttg aggtcttaaa
     1801 aaccctggac ccactggtca ttggaatgcc tcaggtgcta tggccaagga tcctgacttt
     1861 tgtggtacct gcagaataca cagaagctct ggagcccctg tttagtatca tcagaattct
     1921 gattatggca gaggagaaga agcagcacag tgccaaggag tcgacagcac ttgtcgtctc
     1981 tacaggagct gtgaaacttc cttcaccaca gcagctactg gccagacttc tggtaatatc
     2041 tatgcctgcc agtttagggg agttacgtgg ggctggtgca atagggcttt tgaagatact
     2101 gcctgagata attcacccaa aattggtaga cctatggaaa acacgtttac ctgagcttct
     2161 gcagcctctg gaaggaaaga acatcagtac cgttctatgg gaaaccatgc tgcttcagtt
     2221 gctcaaagaa tccttatgga agatcagtga tgtggcctgg accattcagc tgactcagga
     2281 tttcaaacag caaatgggca gttacagcaa taactccact gagaagaaat tcctttggaa
     2341 agccttggga accaccttag catgctgcca agattcagac tttgtaaact cacagattaa
     2401 ggagtttctg actgctccca accaactggg ggatcaaaga cagggaataa catctatttt
     2461 aggatactgt gccgagaacc atttggatat tgttttaaaa gttcttaaaa cattccaaaa
     2521 tcaggaaaag tttttcatga atcgatgtaa gagccttttt tctgggaaaa agagcctgac
     2581 caagacagat gtcatggtca tctatggagc agtggccctc catgctccca agaagcaact
     2641 tctctccaga cttaatcaag atatcatatc ccaagtcctg tctcttcatg gccagtgctc
     2701 tcaggttctg ggcatgtctg tgatgaacaa ggacatggat ctgcaaatga gtttcacaag
     2761 aagcatcact gagattggca ttgctgtcca agatgctgag gatcaggggt tccagttttc
     2821 ctacaaggag atgctgattg gttacatgct ggacttcatt agagacgagc ccctggattc
     2881 cttagctagc cctattcggt ggaaagcctt aatcgccatt aggtatctca gtaaactgaa
     2941 acctcagctc tcactacaag accaccttaa cattcttgag gagaatattc ggaggctgct
     3001 gccccttcca cctctggaaa atctgaaaag tgaaggccag acagacaagg acaaggagca
     3061 cattcaattt ctctatgaac gatccatgga cgccctagga aaacttctga agaccatgat
     3121 gtgggataat gtgaatgcag aggactgtca agaaatgttt aatcttctcc aaatgtggct
     3181 tgtttcacaa aaagagtggg aaagagaaag agccttccag atcactgcga aagtgctgac
     3241 aaatgatatt gaggcaccag agaactttaa aattggttca ctgcttggac ttctggctcc
     3301 tcactcctgt gataccctgc ccaccatccg tcaggcggct gctagctcaa ctattggtct
     3361 gttctatata aaaggcattc acttggaagt ggaaagactg cagggtttgc aggaagggct
     3421 ggaaagtgat gacgtgcagg ttcagatcaa gatttcttct aaaatagcta agattgtcag
     3481 taagttcatc ccaaatgaag aaattctgat gttcctagag gaaatgctgg acggtctgga
     3541 gagcctcaac cccacttgta caaaggcctg tggcatatgg atgatcactg tcctgaagca
     3601 gcagggagct gctctggaag atcagctatt ggagatctta ggcacaatct accatcacat
     3661 gccagtcctc agacaaaaag aagaaagttt tcagttcatt ctagaagcca tctcccagat
     3721 agccagcttt cacatggata cagttgttgt caacctttta cagaagcctc tgccttttga
     3781 cagggacaca aagacattgt ggaaggcgct ggctgaaaag ccagcctcca gtgggaaact
     3841 cttgcaagcc ttaatagaca aactggagac tgagttagaa gatgacatcg ccagggttga
     3901 ggcaatttca gtggcctgtg ctatgtatga agtgatctca atgggcacct ctgtcaccgg
     3961 cttgtatcca gagctgttca ctctcctcct gaagctggtt agctgcacac tgggccagaa
     4021 gatgctcact tgtccctgga gccataggcg gcatgtgatg cagcagggag aacagcagca
     4081 gatcccagac ccctgcaggc tttcaactgc tactttaaaa tgtttgcaag cccaagccat
     4141 gagagaaggc cttgcaaagg aatctgatga gggggacaac ttatggactc tactcagcag
     4201 tcctagtacc caccacatag gcgtatgttc actggccagg agcatggcag tgtggcaaca
     4261 cggagtcata ctggacatca tggaacagct gctctcatct cttacctcct cctcggagaa
     4321 ctaccggata accggcgcag ctttcttctc tgagctcatg aaggaaccaa tcctttggaa
     4381 gcatgggaat ctgcgaaatg tgctgatctt gatggatcaa agtgcctggg actccaacgc
     4441 cactctgagg cagatggcca tccgagggct cggcaacaca gcatccgggg ctcctcacaa
     4501 ggtgaagaaa cataagcagt taatgctaga atctatcatc agaggcctgt atcacctagc
     4561 tcgcactgaa gtcgtctgtg aaagcttgaa ggctctaaaa aaaatcctgg agctgctgac
     4621 agaccgagac gtgagcttct acttcaagga aatagtgctg caaacaagga ccttctttga
     4681 agatgagcag gatgatgtga gattgactgc catcttctta tttgaggacc tggcacccct
     4741 aacaggaaga aggtggaaga ttttttttgc tgaagaaata aaaaagagcc tgatttcatt
     4801 ccttctgcac ctttgggatc ccaaccccaa gattggagtt gcttgccgtg atgtcttgat
     4861 ggtctgcatt ccctttttgg gcctccagga gctctatggg gtattagacc gtctccttga
     4921 tcaggatcta ccaagggcca gggatttcta caggcaattc tgtgtgaaac tggccaagaa
     4981 aaaccaggaa attctgtgga tcctccacac acactccttc accttcttca ccagcacctg
     5041 ggaggtgatc aggagtgcag ctgtcaaact cacagatgcc gttgttctca atttgaccag
     5101 ccaatatgtg gagttactag acagagaaca actgaccaca cgactccaag cacttcgtca
     5161 agatccgtgt attagtgtcc agagagcagc tgaggctgct ttgcaaaccc tcctgagaag
     5221 gtgtaaagag acaagcattc ctctgtaagc catcaagaaa taaactgctg gcttttccta
//
