LOCUS       NM_024761               6487 bp    mRNA    linear   PRI 11-FEB-2025
DEFINITION  Homo sapiens MOB kinase activator 3B (MOB3B), mRNA.
ACCESSION   NM_024761
VERSION     NM_024761.5
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 6487)
  AUTHORS   Elkholi,I.E., Boulais,J., Thibault,M.P., Phan,H.D., Robert,A.,
            Lai,L.B., Faubert,D., Smith,M.J., Gopalan,V. and Cote,J.F.
  TITLE     Mapping the MOB proteins' proximity network reveals a unique
            interaction between human MOB3C and the RNase P complex
  JOURNAL   J Biol Chem 299 (9), 105123 (2023)
   PUBMED   37536630
REFERENCE   2  (bases 1 to 6487)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   3  (bases 1 to 6487)
  AUTHORS   Joung,J., Engreitz,J.M., Konermann,S., Abudayyeh,O.O.,
            Verdine,V.K., Aguet,F., Gootenberg,J.S., Sanjana,N.E., Wright,J.B.,
            Fulco,C.P., Tseng,Y.Y., Yoon,C.H., Boehm,J.S., Lander,E.S. and
            Zhang,F.
  TITLE     Genome-scale activation screen identifies a lncRNA locus regulating
            a gene neighbourhood
  JOURNAL   Nature 548 (7667), 343-346 (2017)
   PUBMED   28792927
  REMARK    Erratum:[Nature. 2017 Sep 20;549(7672):418. doi:
            10.1038/nature24009.. PMID: 28933431]
REFERENCE   4  (bases 1 to 6487)
  AUTHORS   Kim,E.A., Kim,Y.H., Kang,H.W., Yoon,H.Y., Kim,W.T., Kim,Y.J.,
            Yun,S.J., Moon,S.K., Choi,Y.H., Kim,I.Y., Lee,S.C. and Kim,W.J.
  TITLE     Lower Levels of Human MOB3B Are Associated with Prostate Cancer
            Susceptibility and Aggressive Clinicopathological Characteristics
  JOURNAL   J Korean Med Sci 30 (7), 937-942 (2015)
   PUBMED   26130958
  REMARK    GeneRIF: low levels of hMOB3B are closely associated with
            aggressive clinicopathologic features in patients with prostate
            cancer. The results suggest that hMOB3B may act as a tumor
            suppressor in human prostate cancer.
REFERENCE   5  (bases 1 to 6487)
  AUTHORS   Kerns,S.L., Stone,N.N., Stock,R.G., Rath,L., Ostrer,H. and
            Rosenstein,B.S.
  TITLE     A 2-stage genome-wide association study to identify single
            nucleotide polymorphisms associated with development of urinary
            symptoms after radiotherapy for prostate cancer
  JOURNAL   J Urol 190 (1), 102-108 (2013)
   PUBMED   23376709
REFERENCE   6  (bases 1 to 6487)
  AUTHORS   Trynka,G., Zhernakova,A., Romanos,J., Franke,L., Hunt,K.A.,
            Turner,G., Bruinenberg,M., Heap,G.A., Platteel,M., Ryan,A.W., de
            Kovel,C., Holmes,G.K., Howdle,P.D., Walters,J.R., Sanders,D.S.,
            Mulder,C.J., Mearin,M.L., Verbeek,W.H., Trimble,V., Stevens,F.M.,
            Kelleher,D., Barisani,D., Bardella,M.T., McManus,R., van Heel,D.A.
            and Wijmenga,C.
  TITLE     Coeliac disease-associated risk variants in TNFAIP3 and REL
            implicate altered NF-kappaB signalling
  JOURNAL   Gut 58 (8), 1078-1083 (2009)
   PUBMED   19240061
  REMARK    GeneRIF: Observational study of gene-disease association. (HuGE
            Navigator)
REFERENCE   7  (bases 1 to 6487)
  AUTHORS   Venkatesan,K., Rual,J.F., Vazquez,A., Stelzl,U., Lemmens,I.,
            Hirozane-Kishikawa,T., Hao,T., Zenkner,M., Xin,X., Goh,K.I.,
            Yildirim,M.A., Simonis,N., Heinzmann,K., Gebreab,F., Sahalie,J.M.,
            Cevik,S., Simon,C., de Smet,A.S., Dann,E., Smolyar,A.,
            Vinayagam,A., Yu,H., Szeto,D., Borick,H., Dricot,A., Klitgord,N.,
            Murray,R.R., Lin,C., Lalowski,M., Timm,J., Rau,K., Boone,C.,
            Braun,P., Cusick,M.E., Roth,F.P., Hill,D.E., Tavernier,J.,
            Wanker,E.E., Barabasi,A.L. and Vidal,M.
  TITLE     An empirical framework for binary interactome mapping
  JOURNAL   Nat Methods 6 (1), 83-90 (2009)
   PUBMED   19060904
REFERENCE   8  (bases 1 to 6487)
  AUTHORS   Liu,C., Batliwalla,F., Li,W., Lee,A., Roubenoff,R., Beckman,E.,
            Khalili,H., Damle,A., Kern,M., Furie,R., Dupuis,J., Plenge,R.M.,
            Coenen,M.J., Behrens,T.W., Carulli,J.P. and Gregersen,P.K.
  TITLE     Genome-wide association scan identifies candidate polymorphisms
            associated with differential response to anti-TNF treatment in
            rheumatoid arthritis
  JOURNAL   Mol Med 14 (9-10), 575-581 (2008)
   PUBMED   18615156
REFERENCE   9  (bases 1 to 6487)
  AUTHORS   Uhl,G.R., Liu,Q.R., Drgon,T., Johnson,C., Walther,D., Rose,J.E.,
            David,S.P., Niaura,R. and Lerman,C.
  TITLE     Molecular genetics of successful smoking cessation: convergent
            genome-wide association study results
  JOURNAL   Arch Gen Psychiatry 65 (6), 683-693 (2008)
   PUBMED   18519826
  REMARK    GeneRIF: Clinical trial and genome-wide association study of
            gene-disease association, gene-environment interaction, and
            pharmacogenomic / toxicogenomic. (HuGE Navigator)
REFERENCE   10 (bases 1 to 6487)
  AUTHORS   Wang,A.G., Yoon,S.Y., Oh,J.H., Jeon,Y.J., Kim,M., Kim,J.M.,
            Byun,S.S., Yang,J.O., Kim,J.H., Kim,D.G., Yeom,Y.I., Yoo,H.S.,
            Kim,Y.S. and Kim,N.S.
  TITLE     Identification of intrahepatic cholangiocarcinoma related genes by
            comparison with normal liver tissues using expressed sequence tags
  JOURNAL   Biochem Biophys Res Commun 345 (3), 1022-1032 (2006)
   PUBMED   16712791
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from BF511468.1, DB266074.1,
            AK023266.1, AL163192.6 and CN260547.1.
            
            On Nov 23, 2018 this sequence version replaced NM_024761.4.
            
            Summary: The protein encoded by this gene shares similarity with
            the yeast Mob1 protein. Yeast Mob1 binds Mps1p, a protein kinase
            essential for spindle pole body duplication and mitotic checkpoint
            regulation. This gene is located on the opposite strand as the
            interferon kappa precursor (IFNK) gene. [provided by RefSeq, Jul
            2008].
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1803611.192260.1,
                                           SRR1803611.67106.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA2153946, SAMN03267773
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000262244.6/ ENSP00000262244.5
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-33                BF511468.1         39-71
            34-616              DB266074.1         1-583
            617-1391            AK023266.1         584-1358
            1392-6242           AL163192.6         4753-9603           c
            6243-6487           CN260547.1         336-580
FEATURES             Location/Qualifiers
     source          1..6487
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="9"
                     /map="9p21.2"
     gene            1..6487
                     /gene="MOB3B"
                     /gene_synonym="C9orf35; MOB1D; MOBKL2B"
                     /note="MOB kinase activator 3B"
                     /db_xref="GeneID:79817"
                     /db_xref="HGNC:HGNC:23825"
                     /db_xref="MIM:617652"
     exon            1..260
                     /gene="MOB3B"
                     /gene_synonym="C9orf35; MOB1D; MOBKL2B"
                     /inference="alignment:Splign:2.1.0"
     exon            261..876
                     /gene="MOB3B"
                     /gene_synonym="C9orf35; MOB1D; MOBKL2B"
                     /inference="alignment:Splign:2.1.0"
     CDS             459..1109
                     /gene="MOB3B"
                     /gene_synonym="C9orf35; MOB1D; MOBKL2B"
                     /note="monopolar spindle 1 binding, MOB1, domain
                     containing; mps one binder kinase activator-like 2B; mob1
                     homolog 2b; MOB1, Mps One Binder kinase activator-like 2B;
                     MOB kinase activator-like 2B"
                     /codon_start=1
                     /product="MOB kinase activator 3B"
                     /protein_id="NP_079037.3"
                     /db_xref="CCDS:CCDS6520.1"
                     /db_xref="GeneID:79817"
                     /db_xref="HGNC:HGNC:23825"
                     /db_xref="MIM:617652"
                     /translation="MSIALKQVFNKDKTFRPKRKFEPGTQRFELHKRAQASLNSGVDL
                     KAAVQLPSGEDQNDWVAVHVVDFFNRINLIYGTICEFCTERTCPVMSGGPKYEYRWQD
                     DLKYKKPTALPAPQYMNLLMDWIEVQINNEEIFPTCVGVPFPKNFLQICKKILCRLFR
                     VFVHVYIHHFDRVIVMGAEAHVNTCYKHFYYFVTEMNLIDRKELEPLKEMTSRMCH"
     exon            877..1079
                     /gene="MOB3B"
                     /gene_synonym="C9orf35; MOB1D; MOBKL2B"
                     /inference="alignment:Splign:2.1.0"
     exon            1080..6487
                     /gene="MOB3B"
                     /gene_synonym="C9orf35; MOB1D; MOBKL2B"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2545..2550
                     /regulatory_class="polyA_signal_sequence"
                     /gene="MOB3B"
                     /gene_synonym="C9orf35; MOB1D; MOBKL2B"
                     /note="hexamer: ATTAAA"
     polyA_site      2565
                     /gene="MOB3B"
                     /gene_synonym="C9orf35; MOB1D; MOBKL2B"
     regulatory      6466..6471
                     /regulatory_class="polyA_signal_sequence"
                     /gene="MOB3B"
                     /gene_synonym="C9orf35; MOB1D; MOBKL2B"
                     /note="hexamer: AATAAA"
     polyA_site      6487
                     /gene="MOB3B"
                     /gene_synonym="C9orf35; MOB1D; MOBKL2B"
                     /note="major polyA site"
ORIGIN      
        1 agtcgagccc cggccggctg cgcggcgcgc tgggtgcatg agggggctgc tccggagcga
       61 cggcggctgc agctggagcc aggcgctcgc ccgtccgccg gttggctcgc cgggacctcg
      121 cgcaccggcg gcagagtccc ttgcgtggat tggcaagcga cgccccacct gccccgagct
      181 caccattttc tttcgcgctg gctgcagctg acccggcgaa gggagccgac cgggccctgg
      241 gctggaggta aaaccccacg gaaagaacat gaggttccct tggaaatcat tcaagaggaa
      301 gatggaaggg gctgtttaga agagcttaaa agctacaggc tgtaagactg gggcctgagt
      361 gctggcagtg gaaaacactg ttgggctgtg atctctccct gaaaagttcc aggtgccttt
      421 tcgcttcctg caaaagaaag gaagcgaaag agaagaccat gtccatagcc ctgaagcagg
      481 tattcaacaa ggacaagacc ttccgaccca agaggaaatt tgaacctggc acacagaggt
      541 ttgagctgca caaacgggct caggcatccc tcaactcggg tgtggacctg aaggcggctg
      601 tgcagttgcc cagtggggag gaccagaatg actgggtggc agtacatgtg gtggacttct
      661 tcaatcggat caacctcatc tatggcacca tctgtgagtt ctgcaccgag cggacctgtc
      721 ctgtgatgtc agggggcccc aaatatgagt atcggtggca ggatgatctc aagtataaga
      781 agccaacagc gctgccagct ccccagtaca tgaaccttct tatggattgg attgaggttc
      841 agatcaacaa cgaggaaata tttccaacat gcgtgggtgt tcccttccca aagaacttcc
      901 ttcagatctg caagaagatc ctgtgccgcc ttttccgggt ctttgtccac gtctatatcc
      961 accacttcga ccgggtcatt gtgatgggtg cagaggccca tgtcaacacc tgctacaaac
     1021 acttctatta ctttgtcaca gagatgaacc tcatagaccg caaggagcta gagcctttga
     1081 aagaaatgac gagcaggatg tgtcactaat gctccacctc accctttgga agaaaggaaa
     1141 gctgtttcct cctggtgccc tgagcgggca ggaggtggac caccctggct gaaatgacac
     1201 acctactccc aggaacagca gaggtggagg caagcagtga ctcctgagag acattcccca
     1261 ctcactttgt gtgctcttaa ccttctgagt gctgctagcc cagacctgtg gacgaggcag
     1321 accacaacgt gaaagaagga ccagcccctt gaccgttctg gctggggaat tgtccacgag
     1381 gaagcctctg cacttccaca catggcacag ttctgcctgt gacctgccgc ctaagcttta
     1441 ctggaattca ggttttgaga ctgagatgcg tgttcgtatt tttccactta tctgtcttgt
     1501 cagctggccg acttctctgt gattggtttt ttaagtgccg ggtgaatttt ggacctctgg
     1561 atgtgcagca agtttttatg caataagcct tcctttcagg tctctaaaag ctcctgctct
     1621 gatctgtggt ttaacactgt gcagggctgt ggagctctga gacacctgaa cccctaccca
     1681 tcccctgcac ctccctactc tccctgccga ggcgtccata gcatttccct aataaatagt
     1741 tttatcaggg acactccatg gggtggcttg tctctgcccc aaacagggtc ttcacgttct
     1801 aactgcaggg aagagactgg ttactagcgt aaagctgaca agttaccagt tcacctgatc
     1861 agaatgtatt ttttataacc accatcattc cttgtctctt cagtggaaga tattctttcc
     1921 tgtttcccag aagagagaaa taaaagtcct aaataactaa gaatgatcag cgggagcgtt
     1981 gggcatgatt actgcagtgt ttgttcttta ttaaagacag ggagtcgtgg ctgtctctac
     2041 ataatactaa catttcagtg aaaaaagtac aattggttat ttggtacgtg tagatttaac
     2101 acccagacgg ctgacttgta accctcccca ctagccttct gagcatttaa acccagccgt
     2161 cattctctcc ccactccacg ctccccactc ctctgccacg ttatgttacg gcacaaaatt
     2221 aatttctgcc cctgtgattg ggccacggtt gccaaggtaa cagtggagct ggagctaact
     2281 tccttctttc atcctttcca atttttctat tccagaagac agtcagaata atgcattctg
     2341 tactacatcc tgccttttga aacctaaatg agttttcgtt gatgaaatgt tgccttctct
     2401 gattcattca caaaactgtg gtggttctga ccacctgtga cgaggggggt cataatactt
     2461 ccagtgatcc ttttaattta gcaaaatatt tgtcggtgga gggaagtaga taagaatgta
     2521 ttagtgtatt ttaaagtaat aatgattaaa gaataactaa atgactctga ttttgtttta
     2581 tcaatcataa tgtgttaaag ccctctgtgg ctgccacaaa agactagaat catgaaatct
     2641 ttgtccaagc taagaaaggg ctgtctctgt gggtacagtg gcattctctg ttgacctaac
     2701 caagcagcct gaaccttgct ttgtgtctcg taaaggtcat ctcacggaat ccaattgctg
     2761 ctacctcacc atgttgctgt gccctggtca acaataaaca tacttttgtc ccccttccta
     2821 agtaactttg agaggacaag ataggcaaag ttttttccct acatctcttt tggccaaaag
     2881 aatatctgac catcacagag atccagagaa cagaaacaag agcccctaag tcccagcctc
     2941 tgcaatacac agttaccaga tgggaatgca gcacagtggc acagagaggt aactacggag
     3001 cccatgccct ggaggaactc tgtagctgtg catcatggaa cgccacagga tttttacatt
     3061 aaaaagttga atatgttcct gcatttcagc agtgcataat cgagcaggag gctggaatct
     3121 ggagaccttt gttattcatt ctttttaagg ttatttttta ttaactgtgc atatgaaatt
     3181 tccactcaat ttaaaaatcc aaatcttttt aagcttcttg gaagaatttc ctcctgctta
     3241 tattgttaat tgcactaatg aactcttcta gggtaaattc tggcaaacta cccttttttt
     3301 ttttttaatc acagaatatt cctgttccca cagaactttg gcacattctg aagaaaatct
     3361 ctgcagtcaa tttttatctc ctctgcttga ctgcatctaa ctgttcatct ctgttataaa
     3421 tggagcttca gccctctggg tcagagactg acaaccctcc ttcttcttcc taacctgtcc
     3481 tactctcctt ctttttctgc tttcatttta attttgggaa attttaaagt aaaagtttca
     3541 aagttgaaag attatagtga gtacccttat gtcctttagt gcatcagttg ttaatgtttt
     3601 gccttgtttt cttttcttcc tttttttttt ttaagagaag gggtctctcc ctattttacc
     3661 caagctggcc ttgaacccct tgcctcaagt gagcttcaac cttagcctcc tgagtagcca
     3721 ggactatggc atgtaccacc gcacctgcct cacattttct ttctcactgt aaatacacat
     3781 tcttattctt gaaccttctg aaaataagtt gcagacatca tgaaaatgta aaatacttca
     3841 tcatattctt tcttttaata agagcattgt cctataaatc tgcaatattt tcacgcccat
     3901 gaaactgaac actgatactg cataaatcta atatatgatc catattcaaa attctccagt
     3961 tgtccccaaa atatccttta tagctgttta tttttaaatc caggatccaa tcaagaatta
     4021 tacgttatat gtagttgtca ttctcttttg tttcctttaa ttgattagag ttgccctttt
     4081 gtgtgtgtct gagtggtggg tggtggggtg gtgtttgtgt atgatgtgca gtgtgtgtgt
     4141 gtgtggtgtg tctttcatga cactgacatt attaaagagt tcaggcaagt ttgtggaatg
     4201 tcccacaatc tagacttttt tactgattgt ttcctcatta cgagatacag gttacatttt
     4261 ttttcccaag actgctacat gtgtgatgtt gtttccttac tactgcctca cctcaggaag
     4321 cacataatgt ctacttgtct cttttctgat attaggactg atcaggtgtt gtctgcctga
     4381 tccaatcatt atcaagttcc ataattcatt attaagctct gaaattcagg acacatacat
     4441 ttatagagtg tgaggctgtg catacgtaca ttcatccctt aatgttctca aggaggccca
     4501 ggatccccaa aatattataa gcattgcagt cagatgatat agcactagca aagcattcat
     4561 ccctttccat ataacaggag ggaggggaag aaggaagttt ccatgtgcag gcaatacgtg
     4621 agagcatggg caagtgagga tttgtatgct ccctgtagcc agaggtgaaa tattcaacgc
     4681 ttttattttt tctcccgtct tcaatgacct cccatttgga cccatagttt atttatagag
     4741 agcacacact ccctaattgt cagatggttt ttttgggaaa actcttagat agtacagtga
     4801 gttgtgaccc tccaaaggat cacaagtaca taaacagata caaagtattt atgtggtatt
     4861 aaaatttcat ggtgatggtg caagggagag atgattagga agaaaatgtc ttacacggct
     4921 gtaattgaga aatactgatc tagagtcatt tcctgcttct taaattgttc gttttctctt
     4981 ccctgggtat tttctcattt ccaaagaccc agagtctcag agccaggtta agtggaagaa
     5041 actttgagag gtttcttaat caattccttc tatctctcaa accatgccag taacttcctt
     5101 ggtgaaaaaa tctatactcc tctcacagtt cttcgggcat ggaaattcta tagcattctt
     5161 tggtataacc aacccactga accctccaca acatcttgaa ttccattcaa ctcgagctga
     5221 agtattcttt ttgagtttca gtatatcttt tctagtgtcc cacttttaga aaggtccaaa
     5281 gatgatatat aataagtgaa aatacaatta atcagagctt tatttgcata tccattaaat
     5341 atctgaaggc tattaccagt tgtgcttcag cctcctttcc cttgcaattc tcccagggtg
     5401 gcatcctcta cggagtcttg ttgctccatt gttgaccact gatgtaactc aacgtgaaac
     5461 cttcccaaag ctctccacat cactctctgt tatggctgtg accagcagtg aacatgaaaa
     5521 gaacttattt catgccttct ccaaactata ttgtttcttt gctaagtcca gacctgcttt
     5581 ttctacattt ataggttttc tattttaatc gccatgcaaa attctttatc atactcaatc
     5641 attttggttt atcttcctga cttcttacct ttaacatccc tgttaaagat tacactgttg
     5701 ttgtttcaaa aaaaaaaaaa aaaaaacctt aattggcaaa acattaaggg acttgaatag
     5761 aattacactt atctttttgt gctgatttat gtcaatccat cattctggtt attgatggaa
     5821 gcaaattgct tcctatgttc tctaaacctt atgtcccttc catactccat gagtaccaca
     5881 ctgggagaaa acaaaagcaa aaagattgtg ggaaaagtat agccattatc tttgaggaaa
     5941 tgtgtaccaa ggcacaatca ttaaaaggag ttggaggcat catttggttg acactgttgt
     6001 cattcttgtt ctgatcattt tggaccttga agaaattggt gattctctcc tagaattaga
     6061 caaacaaagt gtgtttggaa ataatgattg ttttcctgcc ttaaaaaata tattaacaga
     6121 aagcttttat aacaggctgt ttccctctgg acaggtatta attctgagta agaattttca
     6181 gtgactacat aaggatttgt gtaacttatg aaggaagagt ccatttctaa tcaaataatt
     6241 cgcctgtttt actagcttat agtgatctga tttcagaatt ttcctgtatc ttttttacat
     6301 acatcagaaa aagaaatgtt tactatattt ttggttccat ttatgattgt attaagcatt
     6361 tgactataag gaaaactaac aattaaatca attagaaaag caacataaaa ttaaatgata
     6421 tttaggaaat cagttatatg tgagcttggg tattcaaatg tcacaaataa aaagcatata
     6481 accatta
//
