LOCUS       XM_047433047            2563 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens MAPK interacting serine/threonine kinase 1
            (MKNK1), transcript variant X9, mRNA.
ACCESSION   XM_047433047
VERSION     XM_047433047.1
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000001.11) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2563
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="1"
     gene            1..2563
                     /gene="MKNK1"
                     /gene_synonym="MNK1"
                     /note="MAPK interacting serine/threonine kinase 1; Derived
                     by automated computational analysis using gene prediction
                     method: Gnomon. Supporting evidence includes similarity
                     to: 26 ESTs, 278 long SRA reads, 4 Proteins, and 100%
                     coverage of the annotated genomic feature by RNAseq
                     alignments, including 70 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:8569"
                     /db_xref="HGNC:HGNC:7110"
                     /db_xref="MIM:606724"
     CDS             286..1395
                     /gene="MKNK1"
                     /gene_synonym="MNK1"
                     /codon_start=1
                     /product="MAP kinase-interacting serine/threonine-protein
                     kinase 1 isoform X5"
                     /protein_id="XP_047289003.1"
                     /db_xref="GeneID:8569"
                     /db_xref="HGNC:HGNC:7110"
                     /db_xref="MIM:606724"
                     /translation="MVTGGGRRSGGAGPLTPCQESLKIIEKQAGHSRSRVFREVETLY
                     QCQGNKNILELIEFFEDDTRFYLVFEKLQGGSILAHIQKQKHFNEREASRVVRDVAAA
                     LDFLHTKGIAHRDLKPENILCESPEKVSPVKICDFDLGSGMKLNNSCTPITTPELTTP
                     CGSAEYMAPEVVEVFTDQATFYDKRCDLWSLGVVLYIMLSGYPPFVGHCGADCGWDRG
                     EVCRVCQNKLFESIQEGKYEFPDKDWAHISSEAKDLISKLLVRDAKQRLSAAQVLQHP
                     WVQGQAPEKGLPTPQVLQRNSSTMDLTLFAAEAIALNRQLSQHEENELAEEPEALADG
                     LCSMKLSPPCKSRLARRRALAQAGRGEDRSPPTAL"
ORIGIN      
        1 ctagcaccgc ctcttccgcg ttctcggagg agcgatctgc aggtaggggt gcgcgcgacc
       61 gctccccggc gggagccagc gaaggtttcc atgtcagagg ccgatggaga actgaagatt
      121 gccacctacg cacaaaggcc attgagacac ttcgtgtagc tggaagacac caacttcctg
      181 acaggagctt tatttcattt gggatttcaa gtttacagat ggtatcttct caaaagttgg
      241 aaaaacctat agagatgggc agtagcgaac cccttcccat cgcagatggt gacaggagga
      301 ggaagaagaa gcggaggggc cgggccactg actccttgcc aggaaagttt gaagatcatc
      361 gagaaacaag cagggcacag tcggagtagg gtgtttcgag aggtggagac gctgtatcag
      421 tgtcagggaa acaagaacat tttggagctg attgagttct ttgaagatga cacaaggttt
      481 tacttggtct ttgagaaatt gcaaggaggt tccatcttag cccacatcca gaagcaaaag
      541 cacttcaatg agcgagaagc cagccgagtg gtgcgggacg ttgctgctgc ccttgacttc
      601 ctgcatacca aaggcattgc tcatcgtgat ctgaaaccag aaaatatatt gtgtgaatct
      661 ccagaaaagg tgtctccagt gaaaatctgt gactttgact tgggcagtgg gatgaaactg
      721 aacaactcct gtacccccat aaccacacca gagctgacca ccccatgtgg ctctgcagaa
      781 tacatggccc ctgaggtagt ggaggtcttc acggaccagg ccacattcta cgacaagcgc
      841 tgtgacctgt ggagcctggg cgtggtcctc tacatcatgc tgagtggcta cccacccttc
      901 gtgggtcact gcggggccga ctgtggctgg gaccggggcg aggtctgcag ggtgtgccag
      961 aacaagctgt ttgaaagcat ccaggaaggc aagtatgagt ttcctgacaa ggactgggca
     1021 cacatctcca gtgaagccaa agacctcatc tccaagctcc tggtgcgaga tgcaaagcag
     1081 agacttagcg ccgcccaagt tctgcagcac ccatgggtgc aggggcaagc tccagaaaag
     1141 ggactcccca cgccgcaagt cctccagagg aacagcagca caatggacct gacgctcttc
     1201 gcagctgagg ccatcgccct taaccgccag ctatctcagc acgaagagaa cgaactagca
     1261 gaggagccag aggcactagc tgatggcctc tgctccatga agctttcccc tccctgcaag
     1321 tcacgcctgg cccggagacg ggccctggcc caggcaggcc gtggtgaaga caggagcccg
     1381 cccacagcac tctgaaatgc tccagtcaca ccttataggc cctaggcctg gccaggcatt
     1441 gtcccctgga aacctgtgtg gctaaagtct gctgagcagg cagcagcctc tgctctgtgg
     1501 ctccattcag gctttttcat ctacgaaggc cctgaggttc ccatcaaccc ccatttccct
     1561 agggtcctgg aggaaaaagc tttttccaaa ggggttgtct ttgaaaagga aagcaatcac
     1621 ttctcacttt gcataattgc ctgcagcagg aacatctctt cactgggctc cacctgctca
     1681 cccgcctgca gatctgggat ccagcctgct ctcaccgctg tagctgtggc ggctggggct
     1741 gcagcctgca gggagaagca agaagcatca gttgacagag gctgccgaca cgtgcctctt
     1801 ccctctcttc tctgtcaccc tcctctggcg gtccttccac cttcctctgt cctccggatg
     1861 tcctctttgc ccgtcttctc ccttggctga gcaaagccat cccctcaatt cagggaaggg
     1921 caaggagcct tcctcattca ggaaatcaaa tcagtcttcc ggtctgcagc acggaaaagc
     1981 acataatctt tctttgctgt gactgaaatg tatccctcgt ttatcatccc ctttgtttgt
     2041 gattgctgct aaagtcagta gtatcgtttt tttaaaaaaa aagtttggtg tttttaacca
     2101 tgctgttcca gcaaagatga taccttaaac tcccactgca agcccatgaa cttcccagag
     2161 agtggaacgg cttgctcttc tttctagaat gtccatgcac ttgggtttta atcagcagtt
     2221 ccctattatt ctgattttaa gctgttcctg tgatgaactt agagacagca tcggtgtctg
     2281 ctgctgtgtc cccaggtctt gtgtgggtgg cacagatctg ggcagttaga tagtgctctg
     2341 tgcctaaggt gaagccacac tagggtgaag cctcacttcc ctgtttgagc aatgcagtgc
     2401 ctgctgcccg tgtgcatgaa ggtacagcca ttcagataag tggaactatt gagttacata
     2461 aagaaaatag atttgcattt gtcaggcaga cgtttataca acaccacggt gcttttatac
     2521 attgtgctta ttttaataaa actgaaattc tatgtgtggc cta
//
