LOCUS       XM_047433026            2620 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens MAPK interacting serine/threonine kinase 1
            (MKNK1), transcript variant X4, mRNA.
ACCESSION   XM_047433026
VERSION     XM_047433026.1
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000001.11) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2620
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="1"
     gene            1..2620
                     /gene="MKNK1"
                     /gene_synonym="MNK1"
                     /note="MAPK interacting serine/threonine kinase 1; Derived
                     by automated computational analysis using gene prediction
                     method: Gnomon. Supporting evidence includes similarity
                     to: 2 mRNAs, 31 ESTs, 346 long SRA reads, 20 Proteins, and
                     100% coverage of the annotated genomic feature by RNAseq
                     alignments, including 6 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:8569"
                     /db_xref="HGNC:HGNC:7110"
                     /db_xref="MIM:606724"
     CDS             178..1452
                     /gene="MKNK1"
                     /gene_synonym="MNK1"
                     /codon_start=1
                     /product="MAP kinase-interacting serine/threonine-protein
                     kinase 1 isoform X2"
                     /protein_id="XP_047288982.1"
                     /db_xref="GeneID:8569"
                     /db_xref="HGNC:HGNC:7110"
                     /db_xref="MIM:606724"
                     /translation="MVSSQKLEKPIEMGSSEPLPIADGDRRRKKKRRGRATDSLPGKF
                     EDMYKLTSELLGEGAYAKVQGAVSLQNGKEYAVKIIEKQAGHSRSRVFREVETLYQCQ
                     GNKNILELIEFFEDDTRFYLVFEKLQGGSILAHIQKQKHFNEREASRVVRDVAAALDF
                     LHTKGIAHRDLKPENILCESPEKVSPVKICDFDLGSGMKLNNSCTPITTPELTTPCGS
                     AEYMAPEVVEVFTDQATFYDKRCDLWSLGVVLYIMLSGYPPFVGHCGADCGWDRGEVC
                     RVCQNKLFESIQEGKYEFPDKDWAHISSEAKDLISKLLVRDAKQRLSAAQVLQHPWVQ
                     GQAPEKGLPTPQVLQRNSSTMDLTLFAAEAIALNRQLSQHEENELAEEPEALADGLCS
                     MKLSPPCKSRLARRRALAQAGRGEDRSPPTAL"
ORIGIN      
        1 tttaaaggct cctgcctgtg tggatggctg tccacaggga aaggtttcca tgtcagaggc
       61 cgatggagaa ctgaagattg ccacctacgc acaaaggcca ttgagacact tcgtgtagct
      121 ggaagacacc aacttcctga caggagcttt atttcatttg ggatttcaag tttacagatg
      181 gtatcttctc aaaagttgga aaaacctata gagatgggca gtagcgaacc ccttcccatc
      241 gcagatggtg acaggaggag gaagaagaag cggaggggcc gggccactga ctccttgcca
      301 ggaaagtttg aagatatgta caagctgacc tctgaattgc ttggagaggg agcctatgcc
      361 aaagttcaag gtgccgtgag cctacagaat ggcaaagagt atgccgtcaa aatcatcgag
      421 aaacaagcag ggcacagtcg gagtagggtg tttcgagagg tggagacgct gtatcagtgt
      481 cagggaaaca agaacatttt ggagctgatt gagttctttg aagatgacac aaggttttac
      541 ttggtctttg agaaattgca aggaggttcc atcttagccc acatccagaa gcaaaagcac
      601 ttcaatgagc gagaagccag ccgagtggtg cgggacgttg ctgctgccct tgacttcctg
      661 cataccaaag gcattgctca tcgtgatctg aaaccagaaa atatattgtg tgaatctcca
      721 gaaaaggtgt ctccagtgaa aatctgtgac tttgacttgg gcagtgggat gaaactgaac
      781 aactcctgta cccccataac cacaccagag ctgaccaccc catgtggctc tgcagaatac
      841 atggcccctg aggtagtgga ggtcttcacg gaccaggcca cattctacga caagcgctgt
      901 gacctgtgga gcctgggcgt ggtcctctac atcatgctga gtggctaccc acccttcgtg
      961 ggtcactgcg gggccgactg tggctgggac cggggcgagg tctgcagggt gtgccagaac
     1021 aagctgtttg aaagcatcca ggaaggcaag tatgagtttc ctgacaagga ctgggcacac
     1081 atctccagtg aagccaaaga cctcatctcc aagctcctgg tgcgagatgc aaagcagaga
     1141 cttagcgccg cccaagttct gcagcaccca tgggtgcagg ggcaagctcc agaaaaggga
     1201 ctccccacgc cgcaagtcct ccagaggaac agcagcacaa tggacctgac gctcttcgca
     1261 gctgaggcca tcgcccttaa ccgccagcta tctcagcacg aagagaacga actagcagag
     1321 gagccagagg cactagctga tggcctctgc tccatgaagc tttcccctcc ctgcaagtca
     1381 cgcctggccc ggagacgggc cctggcccag gcaggccgtg gtgaagacag gagcccgccc
     1441 acagcactct gaaatgctcc agtcacacct tataggccct aggcctggcc aggcattgtc
     1501 ccctggaaac ctgtgtggct aaagtctgct gagcaggcag cagcctctgc tctgtggctc
     1561 cattcaggct ttttcatcta cgaaggccct gaggttccca tcaaccccca tttccctagg
     1621 gtcctggagg aaaaagcttt ttccaaaggg gttgtctttg aaaaggaaag caatcacttc
     1681 tcactttgca taattgcctg cagcaggaac atctcttcac tgggctccac ctgctcaccc
     1741 gcctgcagat ctgggatcca gcctgctctc accgctgtag ctgtggcggc tggggctgca
     1801 gcctgcaggg agaagcaaga agcatcagtt gacagaggct gccgacacgt gcctcttccc
     1861 tctcttctct gtcaccctcc tctggcggtc cttccacctt cctctgtcct ccggatgtcc
     1921 tctttgcccg tcttctccct tggctgagca aagccatccc ctcaattcag ggaagggcaa
     1981 ggagccttcc tcattcagga aatcaaatca gtcttccggt ctgcagcacg gaaaagcaca
     2041 taatctttct ttgctgtgac tgaaatgtat ccctcgttta tcatcccctt tgtttgtgat
     2101 tgctgctaaa gtcagtagta tcgttttttt aaaaaaaaag tttggtgttt ttaaccatgc
     2161 tgttccagca aagatgatac cttaaactcc cactgcaagc ccatgaactt cccagagagt
     2221 ggaacggctt gctcttcttt ctagaatgtc catgcacttg ggttttaatc agcagttccc
     2281 tattattctg attttaagct gttcctgtga tgaacttaga gacagcatcg gtgtctgctg
     2341 ctgtgtcccc aggtcttgtg tgggtggcac agatctgggc agttagatag tgctctgtgc
     2401 ctaaggtgaa gccacactag ggtgaagcct cacttccctg tttgagcaat gcagtgcctg
     2461 ctgcccgtgt gcatgaaggt acagccattc agataagtgg aactattgag ttacataaag
     2521 aaaatagatt tgcatttgtc aggcagacgt ttatacaaca ccacggtgct tttatacatt
     2581 gtgcttattt taataaaact gaaattctat gtgtggccta
//
