LOCUS       NM_001199172            4560 bp    mRNA    linear   PRI 06-APR-2024
DEFINITION  Homo sapiens alpha-1,6-mannosylglycoprotein
            6-beta-N-acetylglucosaminyltransferase B (MGAT5B), transcript
            variant 3, mRNA.
ACCESSION   NM_001199172
VERSION     NM_001199172.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 4560)
  AUTHORS   Nagai,K., Muto,Y., Miura,S., Takahashi,K., Naruse,Y., Hiruta,R.,
            Hashimoto,Y., Uzuki,M., Haga,Y., Fujii,R., Ueda,K., Kawaguchi,Y.,
            Fujii,M. and Kitazume,S.
  TITLE     Brain-specific glycosylation enzyme GnT-IX maintains levels of
            protein tyrosine phosphatase receptor PTPRZ, thereby mediating
            glioma growth
  JOURNAL   J Biol Chem 299 (9), 105128 (2023)
   PUBMED   37543361
  REMARK    GeneRIF: Brain-specific glycosylation enzyme GnT-IX maintains
            levels of protein tyrosine phosphatase receptor PTPRZ, thereby
            mediating glioma growth.
REFERENCE   2  (bases 1 to 4560)
  AUTHORS   Kamada,Y., Kida,S., Hirano,K.I., Yamaguchi,S., Suzuki,A.,
            Hashimoto,C., Kimura,A., Sato,M., Fujii,H., Sobajima,T.,
            Yamamoto,A., Ebisutani,Y., Takamatsu,S., Shinzaki,S., Yoshida,Y.,
            Yamada,M., Nagasaka,H., Takehara,T. and Miyoshi,E.
  TITLE     Hepatic aberrant glycosylation by N-acetylglucosaminyltransferase V
            accelerates HDL assembly
  JOURNAL   Am J Physiol Gastrointest Liver Physiol 311 (5), G859-G868 (2016)
   PUBMED   27659420
  REMARK    GeneRIF: we found a strong correlation between serum GnT-V activity
            and HDL-C concentration in human subjects
REFERENCE   3  (bases 1 to 4560)
  AUTHORS   Manichaikul,A., Hoffman,E.A., Smolonska,J., Gao,W., Cho,M.H.,
            Baumhauer,H., Budoff,M., Austin,J.H., Washko,G.R., Carr,J.J.,
            Kaufman,J.D., Pottinger,T., Powell,C.A., Wijmenga,C., Zanen,P.,
            Groen,H.J., Postma,D.S., Wanner,A., Rouhani,F.N., Brantly,M.L.,
            Powell,R., Smith,B.M., Rabinowitz,D., Raffel,L.J., Hinckley
            Stukovsky,K.D., Crapo,J.D., Beaty,T.H., Hokanson,J.E.,
            Silverman,E.K., Dupuis,J., O'Connor,G.T., Boezen,H.M., Rich,S.S.
            and Barr,R.G.
  TITLE     Genome-wide study of percent emphysema on computed tomography in
            the general population. The Multi-Ethnic Study of Atherosclerosis
            Lung/SNP Health Association Resource Study
  JOURNAL   Am J Respir Crit Care Med 189 (4), 408-418 (2014)
   PUBMED   24383474
REFERENCE   4  (bases 1 to 4560)
  AUTHORS   Korekane,H., Park,J.Y., Matsumoto,A., Nakajima,K., Takamatsu,S.,
            Ohtsubo,K., Miyamoto,Y., Hanashima,S., Kanekiyo,K., Kitazume,S.,
            Yamaguchi,Y., Matsuo,I. and Taniguchi,N.
  TITLE     Identification of ectonucleotide pyrophosphatase/phosphodiesterase
            3 (ENPP3) as a regulator of N-acetylglucosaminyltransferase GnT-IX
            (GnT-Vb)
  JOURNAL   J Biol Chem 288 (39), 27912-27926 (2013)
   PUBMED   23960081
  REMARK    GeneRIF: ENPP3 is a regulator of N-acetylglucosaminyltransferase
            GnT-IX (GnT-Vb)
REFERENCE   5  (bases 1 to 4560)
  AUTHORS   Lambert,B., Vandeputte,J., Remacle,S., Bergiers,I., Simonis,N.,
            Twizere,J.C., Vidal,M. and Rezsohazy,R.
  TITLE     Protein interactions of the transcription factor Hoxa1
  JOURNAL   BMC Dev Biol 12, 29 (2012)
   PUBMED   23088713
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 4560)
  AUTHORS   Inamori,K., Mita,S., Gu,J., Mizuno-Horikawa,Y., Miyoshi,E.,
            Dennis,J.W. and Taniguchi,N.
  TITLE     Demonstration of the expression and the enzymatic activity of
            N-acetylglucosaminyltransferase IX in the mouse brain
  JOURNAL   Biochim Biophys Acta 1760 (4), 678-684 (2006)
   PUBMED   16413118
  REMARK    GeneRIF: following human GnT-IX and GnT-V transfection in COS
            cells, antibody specifically recognized GnT-IX, but not GnT-V, in
            the Golgi apparatus
REFERENCE   7  (bases 1 to 4560)
  AUTHORS   Inamori,K., Endo,T., Gu,J., Matsuo,I., Ito,Y., Fujii,S.,
            Iwasaki,H., Narimatsu,H., Miyoshi,E., Honke,K. and Taniguchi,N.
  TITLE     N-Acetylglucosaminyltransferase IX acts on the GlcNAc beta 1,2-Man
            alpha 1-Ser/Thr moiety, forming a 2,6-branched structure in brain
            O-mannosyl glycan
  JOURNAL   J Biol Chem 279 (4), 2337-2340 (2004)
   PUBMED   14617637
REFERENCE   8  (bases 1 to 4560)
  AUTHORS   Guo,H.B., Lee,I., Kamar,M. and Pierce,M.
  TITLE     N-acetylglucosaminyltransferase V expression levels regulate
            cadherin-associated homotypic cell-cell adhesion and intracellular
            signaling pathways
  JOURNAL   J Biol Chem 278 (52), 52412-52424 (2003)
   PUBMED   14561752
  REMARK    GeneRIF: N-linked beta(1,6) branching has a role in cell-cell
            adhesion, cellular motility and neoplasm invasiveness
REFERENCE   9  (bases 1 to 4560)
  AUTHORS   Kaneko,M., Alvarez-Manilla,G., Kamar,M., Lee,I., Lee,J.K.,
            Troupe,K., Zhang,Wj., Osawa,M. and Pierce,M.
  TITLE     A novel beta(1,6)-N-acetylglucosaminyltransferase V (GnT-VB)(1)
  JOURNAL   FEBS Lett 554 (3), 515-519 (2003)
   PUBMED   14623122
REFERENCE   10 (bases 1 to 4560)
  AUTHORS   Inamori,K., Endo,T., Ide,Y., Fujii,S., Gu,J., Honke,K. and
            Taniguchi,N.
  TITLE     Molecular cloning and characterization of human GnT-IX, a novel
            beta1,6-N-acetylglucosaminyltransferase that is specifically
            expressed in the brain
  JOURNAL   J Biol Chem 278 (44), 43102-43109 (2003)
   PUBMED   12941944
  REMARK    GeneRIF: GnT-IX is responsible for the synthesis of a unique
            oligosaccharide structure in the brain
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC016168.18, AB235153.1, BC063862.1 and AW191036.1.
            
            On Jun 2, 2019 this sequence version replaced NM_001199172.1.
            
            Transcript Variant: This variant (3) differs in the 5' UTR and
            coding sequence and contains an alternate in-frame exon compared to
            variant 2. The resulting isoform (3) has a shorter and distinct
            N-terminus and lacks an internal 2 aa segment compared to isoform
            2.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AB235153.1, AB109185.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA2145743, SAMEA2148093
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000569840.7/ ENSP00000456037.2
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-312               AC016168.18        147529-147840       c
            313-3239            AB235153.1         261-3187
            3240-4548           BC063862.1         892-2200
            4549-4556           AW191036.1         9-16                c
            4557-4560           AC016168.18        65851-65854         c
FEATURES             Location/Qualifiers
     source          1..4560
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="17"
                     /map="17q25.2"
     gene            1..4560
                     /gene="MGAT5B"
                     /gene_synonym="GnT-IX; GnT-VB"
                     /note="alpha-1,6-mannosylglycoprotein
                     6-beta-N-acetylglucosaminyltransferase B"
                     /db_xref="GeneID:146664"
                     /db_xref="HGNC:HGNC:24140"
                     /db_xref="MIM:612441"
     exon            1..694
                     /gene="MGAT5B"
                     /gene_synonym="GnT-IX; GnT-VB"
                     /inference="alignment:Splign:2.1.0"
     CDS             627..3005
                     /gene="MGAT5B"
                     /gene_synonym="GnT-IX; GnT-VB"
                     /EC_number="2.4.1.155"
                     /note="isoform 3 is encoded by transcript variant 3;
                     N-acetylglucosaminyltransferase IX;
                     beta(1,6)-N-acetylglucosaminyltransferase V; mannosyl
                     (alpha-1,6-)-glycoprotein
                     beta-1,6-N-acetyl-glucosaminyltransferase, isoenzyme B;
                     mannosyl (alpha-1,6-)-glycoprotein
                     beta-1,6-N-acetyl-glucosaminyltransferase, isozyme B;
                     hGnTVb; glcNAc-T Vb; N-acetylglucosaminyl-transferase Vb;
                     mannoside acetylglucosaminyltransferase 5B;
                     alpha-mannoside beta-1,6-N-acetylglucosaminyltransferase
                     B"
                     /codon_start=1
                     /product="alpha-1,6-mannosylglycoprotein
                     6-beta-N-acetylglucosaminyltransferase B isoform 3"
                     /protein_id="NP_001186101.1"
                     /db_xref="CCDS:CCDS59299.1"
                     /db_xref="GeneID:146664"
                     /db_xref="HGNC:HGNC:24140"
                     /db_xref="MIM:612441"
                     /translation="MITVNPDGKIMVRRCLVTLRPFRLFVLGIGFFTLCFLMTSLGGQ
                     FSARRLGDSPFTIRTEVMGGPESRGVLRKMSDLLELMVKRMDALARLENSSELHRAGG
                     DLHFPADRMPPGAGLMERIQAIAQNVSDIAVKVDQILRHSLLLHSKVSEGRRDQCEAP
                     SDPKFPDCSGKVEWMRARWTSDPCYAFFGVDGTECSFLIYLSEVEWFCPPLPWRNQTA
                     AQRAPKPLPKVQAVFRSNLSHLLDLMGSGKESLIFMKKRTKRLTAQWALAAQRLAQKL
                     GATQRDQKQILVHIGFLTEESGDVFSPRVLKGGPLGEMVQWADILTALYVLGHGLRVT
                     VSLKELQSNLGVPPGRGSCPLTMPLPFDLIYTDYHGLQQMKRHMGLSFKKYRCRIRVI
                     DTFGTEPAYNHEEYATLHGYRTNWGYWNLNPKQFMTMFPHTPDNSFMGFVSEELNETE
                     KRLIKGGKASNMAVVYGKEASIWKLQGKEKFLGILNKYMEIHGTVYYESQRPPEVPAF
                     VKNHGLLPQPEFQQLLRKAKLFIGFGFPYEGPAPLEAIANGCIFLQSRFSPPHSSLNH
                     EFFRGKPTSREVFSQHPYAENFIGKPHVWTVDYNNSEEFEAAIKAIMRTQVDPYLPYE
                     YTCEGMLERIHAYIQHQDFCRAPDPALPEAHAPQSPFVLAPNATHLEWARNTSLAPGA
                     WPPAHALRAWLAVPGRACTDTCLDHGLICEPSFFPFLNSQDAFLKLQVPCDSTESEMN
                     HLYPAFAQPGQECYLQKEPLLFSCAGSNTKYRRLCPCRDFRKGQVALCQGCL"
     exon            695..807
                     /gene="MGAT5B"
                     /gene_synonym="GnT-IX; GnT-VB"
                     /inference="alignment:Splign:2.1.0"
     exon            808..955
                     /gene="MGAT5B"
                     /gene_synonym="GnT-IX; GnT-VB"
                     /inference="alignment:Splign:2.1.0"
     exon            956..1071
                     /gene="MGAT5B"
                     /gene_synonym="GnT-IX; GnT-VB"
                     /inference="alignment:Splign:2.1.0"
     exon            1072..1145
                     /gene="MGAT5B"
                     /gene_synonym="GnT-IX; GnT-VB"
                     /inference="alignment:Splign:2.1.0"
     exon            1146..1316
                     /gene="MGAT5B"
                     /gene_synonym="GnT-IX; GnT-VB"
                     /inference="alignment:Splign:2.1.0"
     exon            1317..1481
                     /gene="MGAT5B"
                     /gene_synonym="GnT-IX; GnT-VB"
                     /inference="alignment:Splign:2.1.0"
     exon            1482..1651
                     /gene="MGAT5B"
                     /gene_synonym="GnT-IX; GnT-VB"
                     /inference="alignment:Splign:2.1.0"
     exon            1652..1783
                     /gene="MGAT5B"
                     /gene_synonym="GnT-IX; GnT-VB"
                     /inference="alignment:Splign:2.1.0"
     exon            1784..1917
                     /gene="MGAT5B"
                     /gene_synonym="GnT-IX; GnT-VB"
                     /inference="alignment:Splign:2.1.0"
     exon            1918..2048
                     /gene="MGAT5B"
                     /gene_synonym="GnT-IX; GnT-VB"
                     /inference="alignment:Splign:2.1.0"
     exon            2049..2054
                     /gene="MGAT5B"
                     /gene_synonym="GnT-IX; GnT-VB"
                     /inference="alignment:Splign:2.1.0"
     exon            2055..2210
                     /gene="MGAT5B"
                     /gene_synonym="GnT-IX; GnT-VB"
                     /inference="alignment:Splign:2.1.0"
     exon            2211..2357
                     /gene="MGAT5B"
                     /gene_synonym="GnT-IX; GnT-VB"
                     /inference="alignment:Splign:2.1.0"
     exon            2358..2474
                     /gene="MGAT5B"
                     /gene_synonym="GnT-IX; GnT-VB"
                     /inference="alignment:Splign:2.1.0"
     exon            2475..2549
                     /gene="MGAT5B"
                     /gene_synonym="GnT-IX; GnT-VB"
                     /inference="alignment:Splign:2.1.0"
     exon            2550..2806
                     /gene="MGAT5B"
                     /gene_synonym="GnT-IX; GnT-VB"
                     /inference="alignment:Splign:2.1.0"
     exon            2807..4560
                     /gene="MGAT5B"
                     /gene_synonym="GnT-IX; GnT-VB"
                     /inference="alignment:Splign:2.1.0"
     regulatory      4522..4527
                     /regulatory_class="polyA_signal_sequence"
                     /gene="MGAT5B"
                     /gene_synonym="GnT-IX; GnT-VB"
                     /note="hexamer: AATAAA"
     polyA_site      4560
                     /gene="MGAT5B"
                     /gene_synonym="GnT-IX; GnT-VB"
                     /note="major polyA site"
ORIGIN      
        1 gctcggccgc ctcctccgag gaacaatgcg gcgcctccgg gcgtagcgtc gcgcggggcc
       61 ggacgccgga caccagagcg cgggcggcgg agccagcggg cgagagagcg cgcggcgggc
      121 gcgggttgcc ctcgtcgaga gccatgggcg cggcgcggcg cggggctgag gatcggcgcg
      181 gcccggaggc gctggggacc ggggcgcggg cccggggccg cctttagccg gcaccgaggg
      241 cgcggggccg gggatgaggg cgcccgccgc ggggagcccg tctgcgcgcc gcggcacctt
      301 cccgcccagc gagcgagccc gagcaggcag acgcgcggcc ggcggtctgg gggcgcgccg
      361 cctcccggtc cccaaaatgt gaagcgggga gggcggagac gcagagacgg cccggccggg
      421 cgccctcgcc gccctccggc agccgcgccg ctccctccgc tgcacgccca ggcctgagca
      481 gcgaggccac cgggccgcgc gctcccagct tcgctcggac gcggcttcgg cccgcagagg
      541 gttcgtggcc cggacgcggc gagagctggg cccaggacgg tgcgtccggc ctcgcccgcg
      601 gctgctcgca ccaacaagtt tgaacaatga tcaccgtcaa ccccgatggg aagataatgg
      661 tcagaagatg cctggtcacc ctgagaccct ttcggctttt tgtcctgggc atcggcttct
      721 tcactctctg cttcctgatg acgtctctgg gaggccagtt ctcggcccgg cgcctggggg
      781 actcgccatt caccatccgc acagaagtga tggggggccc cgagtcccgc ggcgtcctgc
      841 gcaagatgag cgacctgctg gagctgatgg tgaagcgcat ggacgcactg gccaggctgg
      901 agaacagcag tgagctgcac cgggccggcg gcgacctgca ctttcccgca gacaggatgc
      961 cccctggggc cggcctcatg gagcggatcc aggctattgc ccagaacgtc tccgacatcg
     1021 ctgtgaaggt ggaccagatc ctgcgccaca gtctgctcct gcacagcaag gtgtcagaag
     1081 gccggcggga ccagtgtgag gcacccagtg accccaagtt ccctgactgc tcagggaagg
     1141 tggagtggat gcgtgcccgc tggacctctg acccctgcta cgccttcttt ggggtggacg
     1201 gcaccgagtg ctccttcctc atctacctca gtgaggtcga gtggttctgc cccccgctgc
     1261 cctggaggaa ccagacggct gcccagaggg cacccaagcc cctccccaaa gtccaggcag
     1321 ttttccgaag caacctgtcc caccttctgg acctgatggg cagcgggaag gagtccctga
     1381 tcttcatgaa gaagcggacc aagaggctca cagcccagtg ggcgctggct gcccagcgcc
     1441 tggcacagaa gctgggggcc acccagaggg accagaagca gatcctggtc cacatcggct
     1501 tcctgacgga ggagtccggg gacgtgttca gccctcgggt cctgaagggc gggcccctag
     1561 gggagatggt gcagtgggcg gacattctga ctgcactcta tgtcctgggc catggcctgc
     1621 gggtcacagt ctccctgaag gagctgcaga gtaacttagg ggtaccgcca ggccggggaa
     1681 gctgcccgct caccatgccc ctgcccttcg acctcatcta caccgactac cacggcctgc
     1741 agcagatgaa gcggcacatg ggactctcct tcaagaagta ccggtgccga atcagggtca
     1801 tcgacacctt cgggacggaa cctgcgtaca accacgagga gtacgccacg ctgcacggct
     1861 accggaccaa ctggggctac tggaacctca accccaagca gttcatgacc atgtttcctc
     1921 atacccccga caactccttc atgggcttcg tgtccgagga gctcaacgag acggagaagc
     1981 ggctcatcaa aggcggcaag gccagcaaca tggccgtggt gtacggcaag gaggcgagca
     2041 tctggaagct ccaggggaag gagaagttcc tgggcatcct gaacaaatac atggagatcc
     2101 atggcaccgt gtactacgag agccagcggc cccccgaggt gccagccttt gtgaagaacc
     2161 acggcctctt accgcagcct gagtttcagc agctgctgcg caaggccaaa ctcttcatcg
     2221 ggtttggctt cccctacgag ggccccgccc ccctggaggc catcgccaat ggttgcatct
     2281 tcctgcagtc ccgcttcagc ccgccccaca gctccctcaa ccacgagttc ttccgaggca
     2341 agcccacctc cagagaggtg ttctcccagc atccctacgc ggagaacttc atcggcaagc
     2401 cccacgtgtg gacagtcgac tacaacaact cagaggagtt tgaagcagcc atcaaggcca
     2461 ttatgagaac tcaggtagac ccctacctac cctacgagta cacctgcgag gggatgctgg
     2521 agcggatcca cgcctacatc cagcaccagg acttctgcag agctccagac cctgccctac
     2581 cagaggccca cgccccgcag agcccctttg tcctggcccc caatgccacc cacctcgagt
     2641 gggctcggaa caccagcttg gctcctgggg cctggccccc cgcgcacgcc ctgcgggcct
     2701 ggctggccgt gcctgggagg gcctgcaccg acacctgcct ggaccacggg ctaatctgtg
     2761 agccctcctt cttccccttc ctgaacagcc aggacgcctt cctcaagctg caggtgccct
     2821 gtgacagcac cgagtcggag atgaaccacc tgtacccggc gttcgcccag cctggccagg
     2881 agtgctacct gcagaaggag cctctgctct tcagctgcgc cggctccaac accaagtacc
     2941 gccggctctg cccctgccgc gacttccgca agggccaggt ggccttgtgc cagggctgtc
     3001 tgtgaatccg cctctgccgc cctgcctggc acccacgctg gctctctcct gccgcgggag
     3061 aaagcaccag caggttctga gccctggctg cttgtcctcc tcgcaacccc cccaggccgg
     3121 agcttccttc cttagccggg aagctggcag aggagagccg tgcccgggaa taggaggagg
     3181 cagcatgccg agcccctggg acctcccagg caggctccgg ttctctcctg gggactcaca
     3241 gaagcatcgt ggccaagcag gtgtcggact gctcagagtc cgcatggccc aggagcaggt
     3301 ggtcggaggc ccctggcttt gtgcaaggcc ggatctgggc caggtggcga aaggggccca
     3361 gtcgttcttg ggcccaggat ggggcctcta gacttgcaag ggagaggaac agggaccagg
     3421 ctgccccacg gtccctgaag ggtccaagga ggggccctcc ccatggccct ggagagtggg
     3481 cctgggtggt acctgctcca ggcagggaaa ctgggggctc gcccttctcc tgtgagggga
     3541 gccaggcaca cagggcccat tggtgtttgg gatgtggaca gaggggcagg gggctgggag
     3601 aaggctaagc cgaggggtcc tgtttgtgcc tccccttagt cccttccctc ccgatttccc
     3661 gattccccca ccctccctct acacttgagg accacagttg ggggtgtagg gaccacccag
     3721 accctggttg aattgtttct ctctcctgct tgttccaacc cttttcactc tgggcttctc
     3781 ccaaaaccca tcctggcatg acctgcaact ccaggtggtg gatttgttcc aaagcctcaa
     3841 tccctacccc ctccaagggg caggtttcca gtccagcctc agagatcagg ctctgggacc
     3901 cctgcctggg gggtggcctt catgcactag ccacttccgc aggtgctgac tcccgcactc
     3961 cctggcattt tttgcagaca agggcttggg atggaccctc agccccatgg tacgccctgc
     4021 ccagtttcca gttgccctgt ccacttaccc taggtagccc cccaccccat cagtgccgag
     4081 tccttgtccc tacctccagc ttcctccagc ctcaaaccgc ctctggatct agctgtcctt
     4141 ctccgagtgg cacgcctgcc ccaggatgcc ccctttccct cccccccatg cccagagccc
     4201 cgcctgcctc agcgggtcag gccttcagaa cactgccacc cacccagttt tataatcccg
     4261 ctccctctcc aggcaacccc acccaccagc ctaggcctgc tcctccaccc ttcccgggag
     4321 gcagccccgg gatgctgaga gttggtggag gggccaggct ggacgcttcc tgtgggagtc
     4381 ccctccagac ctggctggcc cctgcagcca cagaaaccac gatggcaaaa aatctcattg
     4441 gttctcaagg actaacctgt gggggaaagc aatagagaca ctctttttct ctcttttttt
     4501 taaagattta tttcttgaaa taataaatat tttattggga tgtgaggtgc agaagaggaa
//
