LOCUS       XM_047448733            1387 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens major facilitator superfamily domain
            containing 1 (MFSD1), transcript variant X2, mRNA.
ACCESSION   XM_047448733
VERSION     XM_047448733.1
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq; includes ab initio.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000003.12) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
            
            ##RefSeq-Attributes-START##
            ab initio :: 14% of CDS bases
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1387
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="3"
     gene            1..1387
                     /gene="MFSD1"
                     /gene_synonym="Minerva; SMAP4"
                     /note="major facilitator superfamily domain containing 1;
                     Derived by automated computational analysis using gene
                     prediction method: Gnomon. Supporting evidence includes
                     similarity to: 1 mRNA, 47 ESTs, 40 long SRA reads, 3
                     Proteins, and 87% coverage of the annotated genomic
                     feature by RNAseq alignments, including 137 samples with
                     support for all annotated introns"
                     /db_xref="GeneID:64747"
                     /db_xref="HGNC:HGNC:25874"
                     /db_xref="MIM:619976"
     CDS             278..1384
                     /gene="MFSD1"
                     /gene_synonym="Minerva; SMAP4"
                     /codon_start=1
                     /product="lysosomal dipeptide transporter MFSD1 isoform
                     X2"
                     /protein_id="XP_047304689.1"
                     /db_xref="GeneID:64747"
                     /db_xref="HGNC:HGNC:25874"
                     /db_xref="MIM:619976"
                     /translation="MIILLPFRLKLNEWGTIIFSCFVCIGQVVFALGGIFNAFWLMEF
                     GRFVFGIGGESLAVAQNTYAVSWFKGKELNLVFGLQLSMARIGSTVNMNLMGWLYSKI
                     EALLGSAGHTTLGITLMIGGITCILSLICALALAYLDQRAERILHKEQGKTGEVIKLT
                     DVKDFSLPLWLIFIICVCYYVAVFPFIGLGKVFFTEKFGFSSQAASAINSVVYVISAP
                     MSPVFGLLVDKTGKNIIWVLCAVAATLVSHMMLAFTMWNPWIAMCLLGLSYSLLACAL
                     WPMVAFVVPEHQLGTAYGFMQSIQNLGLAIISIIAGMILDSRGYLFLEVFFIACVSLS
                     LLSVVLLYLVNRAQGGNLNYSARQREEIKFSHTE"
     polyA_site      1387
                     /gene="MFSD1"
                     /gene_synonym="Minerva; SMAP4"
                     /experiment="COORDINATES: polyA evidence [ECO:0006239]"
ORIGIN      
        1 agtcatgtga ccgccgtctt gacagtgttc cacgggcgct gcttcctgcc tgggtttgga
       61 gttgtcacca ctttcccctc tccgtctcct gcgggcgcaa tggaggagga ggatgaggaa
      121 gcgcgggcgc tcctggcagg cggccctgac gaggccgaca gaggtgcccc ggccgcccct
      181 ggagccctgc cggccctctg cgaccccagt cgcctggcgc accggctttt ggtgctgtta
      241 ctgatgtgct tccttggctt tggcagctat ttttgctatg ataatcctgc tgcccttcag
      301 actcaagtta aacgaatggg gcacaatcat ttttagctgc tttgtttgca ttggacaggt
      361 tgtttttgcc ctgggtggaa tatttaatgc tttttggctg atggaatttg gaagatttgt
      421 atttgggatt ggtggcgagt ccttagcagt tgcccagaat acatatgctg tgagctggtt
      481 taaaggcaaa gaattaaacc tggtgtttgg acttcaactt agcatggcta gaattggaag
      541 tacagtaaac atgaacctca tgggatggct gtattctaag attgaagctt tgttaggttc
      601 tgctggtcac acaaccctcg ggatcacact tatgattggg ggtataacgt gtattctttc
      661 actaatctgt gccttggctc ttgcctactt ggatcagaga gcagagagaa tccttcataa
      721 agaacaagga aaaacaggtg aagttattaa attaactgat gtaaaggact tctccttacc
      781 cctgtggctt atatttatca tctgtgtctg ctattatgtt gctgtgttcc cttttattgg
      841 acttgggaaa gttttcttta cagagaaatt tggattttct tcccaggcag caagtgcaat
      901 taacagtgtt gtatatgtca tatcagctcc catgtccccg gtgtttgggc tcctggtgga
      961 taaaacaggg aagaacatca tctgggttct ttgcgcagta gcagccactc ttgtgtccca
     1021 catgatgctg gcctttacga tgtggaaccc ttggattgct atgtgtcttc tgggactctc
     1081 ctactcattg cttgcctgtg cattgtggcc aatggtggca tttgtagttc ctgaacatca
     1141 gctgggaact gcatatggct tcatgcagtc cattcagaat cttgggttgg ccatcatttc
     1201 catcattgct ggtatgatac tggattctcg ggggtatttg tttttggaag tgttcttcat
     1261 tgcctgtgtt tctttgtcac ttttatctgt ggtcttactc tatttggtga atcgtgccca
     1321 gggtgggaac ctaaattatt ctgcaagaca aagggaagaa ataaaatttt cccatactga
     1381 gtaagta
//
