LOCUS       NM_032366                797 bp    mRNA    linear   PRI 09-FEB-2024
DEFINITION  Homo sapiens methyltransferase like 26 (METTL26), transcript
            variant 1, mRNA.
ACCESSION   NM_032366
VERSION     NM_032366.5
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 797)
  AUTHORS   Oh,J.H., Yang,J.O., Hahn,Y., Kim,M.R., Byun,S.S., Jeon,Y.J.,
            Kim,J.M., Song,K.S., Noh,S.M., Kim,S., Yoo,H.S., Kim,Y.S. and
            Kim,N.S.
  TITLE     Transcriptome analysis of human gastric cancer
  JOURNAL   Mamm Genome 16 (12), 942-954 (2005)
   PUBMED   16341674
REFERENCE   2  (bases 1 to 797)
  AUTHORS   Daniels,R.J., Peden,J.F., Lloyd,C., Horsley,S.W., Clark,K.,
            Tufarelli,C., Kearney,L., Buckle,V.J., Doggett,N.A., Flint,J. and
            Higgs,D.R.
  TITLE     Sequence, structure and pathology of the fully annotated terminal 2
            Mb of the short arm of human chromosome 16
  JOURNAL   Hum Mol Genet 10 (4), 339-352 (2001)
   PUBMED   11157797
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            DB499720.1 and AK294482.1.
            
            On Nov 23, 2018 this sequence version replaced NM_032366.4.
            
            Transcript Variant: This variant (1) encodes isoform a.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BQ934893.1, SRR1163658.448529.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA1965299,
                                           SAMEA1966682 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000301686.13/ ENSP00000445926.2
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-3                 DB499720.1         62-64
            4-797               AK294482.1         1-794
FEATURES             Location/Qualifiers
     source          1..797
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="16"
                     /map="16p13.3"
     gene            1..797
                     /gene="METTL26"
                     /gene_synonym="C16orf13; JFP2"
                     /note="methyltransferase like 26"
                     /db_xref="GeneID:84326"
                     /db_xref="HGNC:HGNC:14141"
     exon            1..212
                     /gene="METTL26"
                     /gene_synonym="C16orf13; JFP2"
                     /inference="alignment:Splign:2.1.0"
     CDS             16..630
                     /gene="METTL26"
                     /gene_synonym="C16orf13; JFP2"
                     /note="isoform a is encoded by transcript variant 1;
                     UPF0585 protein C16orf13"
                     /codon_start=1
                     /product="methyltransferase-like 26 isoform a"
                     /protein_id="NP_115742.3"
                     /db_xref="CCDS:CCDS45368.1"
                     /db_xref="GeneID:84326"
                     /db_xref="HGNC:HGNC:14141"
                     /translation="MLVAAAAERNKDPILHVLRQYLDPAQRGVRVLEVASGSGQHAAH
                     FARAFPLAEWQPSDVDQRCLDSIAATTQAQGLTNVKAPLHLDVTWGWEHWGGILPQSL
                     DLLLCINMAHVSPLRCTEGLFRAAGHLLKPRALLITYGPYAINGKISPQSNVDFDLML
                     RCRNPEWGLRDTALLEDLGKASGLLLERMVDMPANNKCLIFRKN"
     exon            213..375
                     /gene="METTL26"
                     /gene_synonym="C16orf13; JFP2"
                     /inference="alignment:Splign:2.1.0"
     exon            376..435
                     /gene="METTL26"
                     /gene_synonym="C16orf13; JFP2"
                     /inference="alignment:Splign:2.1.0"
     exon            436..503
                     /gene="METTL26"
                     /gene_synonym="C16orf13; JFP2"
                     /inference="alignment:Splign:2.1.0"
     exon            504..582
                     /gene="METTL26"
                     /gene_synonym="C16orf13; JFP2"
                     /inference="alignment:Splign:2.1.0"
     exon            583..797
                     /gene="METTL26"
                     /gene_synonym="C16orf13; JFP2"
                     /inference="alignment:Splign:2.1.0"
     regulatory      775..780
                     /regulatory_class="polyA_signal_sequence"
                     /gene="METTL26"
                     /gene_synonym="C16orf13; JFP2"
                     /note="hexamer: AATAAA"
     polyA_site      797
                     /gene="METTL26"
                     /gene_synonym="C16orf13; JFP2"
                     /note="major polyA site"
ORIGIN      
        1 gttgttgctg ccgcgatgct ggtggcggcg gccgcggagc ggaacaagga tcccatcttg
       61 cacgtgctgc ggcagtacct ggatccggcc cagcgtggcg tccgcgtcct cgaggtggcc
      121 tcgggctccg gccagcacgc agcgcacttc gcgcgggcct tccccctggc cgagtggcag
      181 ccgtcggacg tggaccagcg ctgcctggac agcatcgcgg ccaccacgca agcccagggc
      241 ctgaccaacg tgaaggcccc gctacacctg gacgtgacgt ggggctggga gcactggggc
      301 gggatcctgc cacagtcgct ggacctgttg ctctgcatca acatggccca tgtcagcccc
      361 ctgcgctgca cggaggggct cttcagagca gcaggacacc tgctcaaacc cagggccctg
      421 ctcatcacct acgggcccta tgccatcaat gggaagatct ccccccagag caacgtggac
      481 tttgacctga tgctcagatg caggaaccca gaatgggggc ttcgggacac agccctcctg
      541 gaggacctgg gaaaggccag tggcctgctc ctggagagga tggtggacat gccagccaac
      601 aacaaatgcc tgatcttccg gaaaaactaa gcccctcctt cacccccgca cacctgcatc
      661 cctgccggag gctctgtgag gcacgaaccc tgcctcccta ggccggacct tgtggacgac
      721 agccccaccc agtctgtgct ctcagccgct ggccgaaggg cccagcctgc tcagaataaa
      781 gcatgtcctg ctgccgg
//
