LOCUS       XM_047442122            9772 bp    mRNA    linear   PRI 26-AUG-2024
DEFINITION  PREDICTED: Homo sapiens methyl-CpG binding protein 2 (MECP2),
            transcript variant X9, mRNA.
ACCESSION   XM_047442122
VERSION     XM_047442122.1
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000023.11) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9772
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="X"
     gene            1..9772
                     /gene="MECP2"
                     /gene_synonym="AUTSX3; MRX16; MRX79; MRXS13; MRXSL; PPMX;
                     RS; RTS; RTT"
                     /note="methyl-CpG binding protein 2; Derived by automated
                     computational analysis using gene prediction method:
                     Gnomon. Supporting evidence includes similarity to: 21
                     ESTs, 1599 long SRA reads, 1 Protein, and 100% coverage of
                     the annotated genomic feature by RNAseq alignments,
                     including 104 samples with support for all annotated
                     introns"
                     /db_xref="GeneID:4204"
                     /db_xref="HGNC:HGNC:6990"
                     /db_xref="MIM:300005"
     CDS             187..978
                     /gene="MECP2"
                     /gene_synonym="AUTSX3; MRX16; MRX79; MRXS13; MRXSL; PPMX;
                     RS; RTS; RTT"
                     /codon_start=1
                     /product="methyl-CpG-binding protein 2 isoform X3"
                     /protein_id="XP_047298078.1"
                     /db_xref="GeneID:4204"
                     /db_xref="HGNC:HGNC:6990"
                     /db_xref="MIM:300005"
                     /translation="MPFQTSPGGKAEGGGATTSTQVMVIKRPGRKRKAEADPQAIPKK
                     RGRKPGSVVAAAAAEAKKKAVKESSIRSVQETVLPIKKRKTRETVSIEVKEVVKPLLV
                     STLGEKSGKGLKTCKSPGRKSKESSPKGRSSSASSPPKKEHHHHHHHSESPKAPVPLL
                     PPLPPPPPEPESSEDPTSPPEPQDLSSSVCKEEKMPRGGSLESDGCPKEPAKTQPAVA
                     TAATAAEKYKHRGEGERKDIVSSSMPRPNREEPVDSRTPVTERVS"
ORIGIN      
        1 cagtccccag ggaaaagcct ttcgctctaa agtggagttg attgcgtact tcgaaaagct
       61 ccaggaactg gcagaggccg gggacgcccc aaagggagcg gcaccacgag acccaaggcg
      121 gccacgtcag agggtgtgca ggtgaaaagg gtcctggaga aaagtcctgg gaagctcctt
      181 gtcaagatgc cttttcaaac ttcgccaggg ggcaaggctg aggggggtgg ggccaccaca
      241 tccacccagg tcatggtgat caaacgcccc ggcaggaagc gaaaagctga ggccgaccct
      301 caggccattc ccaagaaacg gggccgaaag ccggggagtg tggtggcagc cgctgccgcc
      361 gaggccaaaa agaaagccgt gaaggagtct tctatccgat ctgtgcagga gaccgtactc
      421 cccatcaaga agcgcaagac ccgggagacg gtcagcatcg aggtcaagga agtggtgaag
      481 cccctgctgg tgtccaccct cggtgagaag agcgggaaag gactgaagac ctgtaagagc
      541 cctgggcgga aaagcaagga gagcagcccc aaggggcgca gcagcagcgc ctcctcaccc
      601 cccaagaagg agcaccacca ccatcaccac cactcagagt ccccaaaggc ccccgtgcca
      661 ctgctcccac ccctgccccc acctccacct gagcccgaga gctccgagga ccccaccagc
      721 ccccctgagc cccaggactt gagcagcagc gtctgcaaag aggagaagat gcccagagga
      781 ggctcactgg agagcgacgg ctgccccaag gagccagcta agactcagcc cgcggttgcc
      841 accgccgcca cggccgcaga aaagtacaaa caccgagggg agggagagcg caaagacatt
      901 gtttcatcct ccatgccaag gccaaacaga gaggagcctg tggacagccg gacgcccgtg
      961 accgagagag ttagctgact ttacacggag cggattgcaa agcaaaccaa caagaataaa
     1021 ggcagctgtt gtctcttctc cttatgggta gggctctgac aaagcttccc gattaactga
     1081 aataaaaaat attttttttt ctttcagtaa acttagagtt tcgtggcttc agggtgggag
     1141 tagttggagc attggggatg tttttcttac cgacaagcac agtcaggttg aagacctaac
     1201 cagggccaga agtagctttg cacttttcta aactaggctc cttcaacaag gcttgctgca
     1261 gatactactg accagacaag ctgttgacca ggcacctccc ctcccgccca aacctttccc
     1321 ccatgtggtc gttagagaca gagcgacaga gcagttgaga ggacactccc gttttcggtg
     1381 ccatcagtgc cccgtctaca gctcccccag ctccccccac ctcccccact cccaaccacg
     1441 ttgggacagg gaggtgtgag gcaggagaga cagttggatt ctttagagaa gatggatatg
     1501 accagtggct atggcctgtg cgatcccacc cgtggtggct caagtctggc cccacaccag
     1561 ccccaatcca aaactggcaa ggacgcttca caggacagga aagtggcacc tgtctgctcc
     1621 agctctggca tggctaggag gggggagtcc cttgaactac tgggtgtaga ctggcctgaa
     1681 ccacaggaga ggatggccca gggtgaggtg gcatggtcca ttctcaaggg acgtcctcca
     1741 acgggtggcg ctagaggcca tggaggcagt aggacaaggt gcaggcaggc tggcctgggg
     1801 tcaggccggg cagagcacag cggggtgaga gggattccta atcactcaga gcagtctgtg
     1861 acttagtgga caggggaggg ggcaaagggg gaggagaaga aaatgttctt ccagttactt
     1921 tccaattctc ctttagggac agcttagaat tatttgcact attgagtctt catgttccca
     1981 cttcaaaaca aacagatgct ctgagagcaa actggcttga attggtgaca tttagtccct
     2041 caagccacca gatgtgacag tgttgagaac tacctggatt tgtatatata cctgcgcttg
     2101 ttttaaagtg ggctcagcac atagggttcc cacgaagctc cgaaactcta agtgtttgct
     2161 gcaattttat aaggacttcc tgattggttt ctcttctccc cttccatttc tgccttttgt
     2221 tcatttcatc ctttcacttc tttcccttcc tccatcctcc tccttcctag ttcatccctt
     2281 ctcttccagg cagccgcggt gcccaaccac acttgtcggc tccagtcccc agaactctgc
     2341 ctgccctttg tcctcctgct gccagtacca gccccaccct gttttgagcc ctgaggaggc
     2401 cttgggctct gctgagtccg acctggcctg tctgtgaaga gcaagagagc agcaaggtct
     2461 tgctctccta ggtagccccc tcttccctgg taagaaaaag caaaaggcat ttcccaccct
     2521 gaacaacgag ccttttcacc cttctactct agagaagtgg actggaggag ctgggcccga
     2581 tttggtagtt gaggaaagca cagaggcctc ctgtggcctg ccagtcatcg agtggcccaa
     2641 caggggctcc atgccagccg accttgacct cactcagaag tccagagtct agcgtagtgc
     2701 agcagggcag tagcggtacc aatgcagaac tcccaagacc cgagctggga ccagtacctg
     2761 ggtccccagc ccttcctctg ctcccccttt tccctcggag ttcttcttga atggcaatgt
     2821 tttgcttttg ctcgatgcag acagggggcc agaacaccac acatttcact gtctgtctgg
     2881 tccatagctg tggtgtaggg gcttagaggc atgggcttgc tgtgggtttt taattgatca
     2941 gttttcatgt gggatcccat ctttttaacc tctgttcagg aagtccttat ctagctgcat
     3001 atcttcatca tattggtata tccttttctg tgtttacaga gatgtctctt atatctaaat
     3061 ctgtccaact gagaagtacc ttatcaaagt agcaaatgag acagcagtct tatgcttcca
     3121 gaaacaccca caggcatgtc ccatgtgagc tgctgccatg aactgtcaag tgtgtgttgt
     3181 cttgtgtatt tcagttattg tccctggctt ccttactatg gtgtaatcat gaaggagtga
     3241 aacatcatag aaactgtcta gcacttcctt gccagtcttt agtgatcagg aaccatagtt
     3301 gacagttcca atcagtagct taagaaaaaa ccgtgtttgt ctcttctgga atggttagaa
     3361 gtgagggagt ttgccccgtt ctgtttgtag agtctcatag ttggactttc tagcatatat
     3421 gtgtccattt ccttatgctg taaaagcaag tcctgcaacc aaactcccat cagcccaatc
     3481 cctgatccct gatcccttcc acctgctctg ctgatgaccc ccccagcttc acttctgact
     3541 cttccccagg aagggaaggg gggtcagaag agagggtgag tcctccagaa ctcttcctcc
     3601 aaggacagaa ggctcctgcc cccatagtgg cctcgaactc ctggcactac caaaggacac
     3661 ttatccacga gagcgcagca tccgaccagg ttgtcactga gaagatgttt attttggtca
     3721 gttgggtttt tatgtattat acttagtcaa atgtaatgtg gcttctggaa tcattgtcca
     3781 gagctgcttc cccgtcacct gggcgtcatc tggtcctggt aagaggagtg cgtggcccac
     3841 caggcccccc tgtcacccat gacagttcat tcagggccga tggggcagtc gtggttggga
     3901 acacagcatt tcaagcgtca ctttatttca ttcgggcccc acctgcagct ccctcaaaga
     3961 ggcagttgcc cagcctcttt cccttccagt ttattccaga gctgccagtg gggcctgagg
     4021 ctccttaggg ttttctctct atttccccct ttcttcctca ttccctcgtc tttcccaaag
     4081 gcatcacgag tcagtcgcct ttcagcaggc agccttggcg gtttatcgcc ctggcaggca
     4141 ggggccctgc agctctcatg ctgcccctgc cttggggtca ggttgacagg aggttggagg
     4201 gaaagcctta agctgcagga ttctcaccag ctgtgtccgg cccagttttg gggtgtgacc
     4261 tcaatttcaa ttttgtctgt acttgaacat tatgaagatg ggggcctctt tcagtgaatt
     4321 tgtgaacagc agaattgacc gacagctttc cagtacccat ggggctaggt cattaaggcc
     4381 acatccacag tctcccccac ccttgttcca gttgttagtt actacctcct ctcctgacaa
     4441 tactgtatgt cgtcgagctc cccccaggtc tacccctccc ggccctgcct gctggtgggc
     4501 ttgtcatagc cagtgggatt gccggtcttg acagctcagt gagctggaga tacttggtca
     4561 cagccaggcg ctagcacagc tcccttctgt tgatgctgta ttcccatatc aaaagacaca
     4621 ggggacaccc agaaacgcca catcccccaa tccatcagtg ccaaactagc caacggcccc
     4681 agcttctcag ctcgctggat ggcggaagct gctactcgtg agcgccagtg cgggtgcaga
     4741 caatcttctg ttgggtggca tcattccagg cccgaagcat gaacagtgca cctgggacag
     4801 ggagcagccc caaattgtca cctgcttctc tgcccagctt ttcattgctg tgacagtgat
     4861 ggcgaaagag ggtaataacc agacacaaac tgccaagttg ggtggagaaa ggagtttctt
     4921 tagctgacag aatctctgaa ttttaaatca cttagtaagc ggctcaagcc caggagggag
     4981 cagagggata cgagcggagt cccctgcgcg ggaccatctg gaattggttt agcccaagtg
     5041 gagcctgaca gccagaactc tgtgtccccc gtctaaccac agctcctttt ccagagcatt
     5101 ccagtcaggc tctctgggct gactgggcca ggggaggtta caggtaccag ttctttaaga
     5161 agatctttgg gcatatacat ttttagcctg tgtcattgcc ccaaatggat tcctgtttca
     5221 agttcacacc tgcagattct aggacctgtg tcctagactt cagggagtca gctgtttcta
     5281 gagttcctac catggagtgg gtctggagga cctgcccggt gggggggcag agccctgctc
     5341 cctccgggtc ttcctactct tctctctgct ctgacgggat ttgttgattc tctccatttt
     5401 ggtgtctttc tcttttagat attgtatcaa tctttagaaa aggcatagtc tacttgttat
     5461 aaatcgttag gatactgcct cccccagggt ctaaaattac atattagagg ggaaaagctg
     5521 aacactgaag tcagttctca acaatttaga aggaaaacct agaaaacatt tggcagaaaa
     5581 ttacatttcg atgtttttga atgaatacga gcaagctttt acaacagtgc tgatctaaaa
     5641 atacttagca cttggcctga gatgcctggt gagcattaca ggcaagggga atctggaggt
     5701 agccgacctg aggacatggc ttctgaacct gtcttttggg agtggtatgg aaggtggagc
     5761 gttcaccagt gacctggaag gcccagcacc accctccttc ccactcttct catcttgaca
     5821 gagcctgccc cagcgctgac gtgtcaggaa aacacccagg gaactaggaa ggcacttctg
     5881 cctgaggggc agcctgcctt gcccactcct gctctgctcg cctcggatca gctgagcctt
     5941 ctgagctggc ctctcactgc ctccccaagg ccccctgcct gccctgtcag gaggcagaag
     6001 gaagcaggtg tgagggcagt gcaaggaggg agcacaaccc ccagctcccg ctccgggctc
     6061 cgacttgtgc acaggcagag cccagaccct ggaggaaatc ctacctttga attcaagaac
     6121 atttggggaa tttggaaatc tctttgcccc caaaccccca ttctgtccta cctttaatca
     6181 ggtcctgctc agcagtgaga gcagatgagg tgaaaaggcc aagaggtttg gctcctgccc
     6241 actgatagcc cctctccccg cagtgtttgt gtgtcaagtg gcaaagctgt tcttcctggt
     6301 gaccctgatt atatccagta acacatagac tgtgcgcata ggcctgcttt gtctcctcta
     6361 tcctgggctt ttgttttgct ttttagtttt gcttttagtt tttctgtccc ttttatttaa
     6421 cgcaccgact agacacacaa agcagttgaa tttttatata tatatctgta tattgcacaa
     6481 ttataaactc attttgcttg tggctccaca cacacaaaaa aagacctgtt aaaattatac
     6541 ctgttgctta attacaatat ttctgataac catagcatag gacaagggaa aataaaaaaa
     6601 gaaaaaaaag aaaaaaaaac gacaaatctg tctgctggtc acttcttctg tccaagcaga
     6661 ttcgtggtct tttcctcgct tctttcaagg gctttcctgt gccaggtgaa ggaggctcca
     6721 ggcagcaccc aggttttgca ctcttgtttc tcccgtgctt gtgaaagagg tcccaaggtt
     6781 ctgggtgcag gagcgctccc ttgacctgct gaagtccgga acgtagtcgg cacagcctgg
     6841 tcgccttcca cctctgggag ctggagtcca ctggggtggc ctgactcccc cagtcccctt
     6901 cccgtgacct ggtcagggtg agcccatgtg gagtcagcct cgcaggcctc cctgccagta
     6961 gggtccgagt gtgtttcatc cttcccactc tgtcgagcct gggggctgga gcggagacgg
     7021 gaggcctggc ctgtctcgga acctgtgagc tgcaccaggt agaacgccag ggaccccaga
     7081 atcatgtgcg tcagtccaag gggtcccctc caggagtagt gaagactcca gaaatgtccc
     7141 tttcttctcc cccatcctac gagtaattgc atttgctttt gtaattctta atgagcaata
     7201 tctgctagag agtttagctg taacagttct ttttgatcat ctttttttaa taattagaaa
     7261 caccaaaaaa atccagaaac ttgttcttcc aaagcagaga gcattataat caccagggcc
     7321 aaaagcttcc ctccctgctg tcattgcttc ttctgaggcc tgaatccaaa agaaaaacag
     7381 ccataggccc tttcagtggc cgggctaccc gtgagccctt cggaggacca gggctggggc
     7441 agcctctggg cccacatccg gggccagctc cggcgtgtgt tcagtgttag cagtgggtca
     7501 tgatgctctt tcccacccag cctgggatag gggcagagga ggcgaggagg ccgttgccgc
     7561 tgatgtttgg ccgtgaacag gtgggtgtct gcgtgcgtcc acgtgcgtgt tttctgactg
     7621 acatgaaatc gacgcccgag ttagcctcac ccggtgacct ctagccctgc ccggatggag
     7681 cggggcccac ccggttcagt gtttctgggg agctggacag tggagtgcaa aaggcttgca
     7741 gaacttgaag cctgctcctt cccttgctac cacggcctcc tttccgtttg atttgtcact
     7801 gcttcaatca ataacagccg ctccagagtc agtagtcaat gaatatatga ccaaatatca
     7861 ccaggactgt tactcaatgt gtgccgagcc cttgcccatg ctgggctccc gtgtatctgg
     7921 acactgtaac gtgtgctgtg tttgctcccc ttccccttcc ttctttgccc tttacttgtc
     7981 tttctggggt ttttctgttt gggtttggtt tggtttttat ttctcctttt gtgttccaaa
     8041 catgaggttc tctctactgg tcctcttaac tgtggtgttg aggcttatat ttgtgtaatt
     8101 tttggtgggt gaaaggaatt ttgctaagta aatctcttct gtgtttgaac tgaagtctgt
     8161 attgtaacta tgtttaaagt aattgttcca gagacaaata tttctagaca ctttttcttt
     8221 acaaacaaaa gcattcggag ggagggggat ggtgactgag atgagagggg agagctgaac
     8281 agatgacccc tgcccagatc agccagaagc cacccaaagc agtggagccc aggagtccca
     8341 ctccaagcca gcaagccgaa tagctgatgt gttgccactt tccaagtcac tgcaaaacca
     8401 ggttttgttc cgcccagtgg attcttgttt tgcttcccct ccccccgaga ttattaccac
     8461 catcccgtgc ttttaaggaa aggcaagatt gatgtttcct tgaggggagc caggagggga
     8521 tgtgtgtgtg cagagctgaa gagctgggga gaatggggct gggcccaccc aagcaggagg
     8581 ctgggacgct ctgctgtggg cacaggtcag gctaatgttg gcagatgcag ctcttcctgg
     8641 acaggccagg tggtgggcat tctctctcca aggtgtgccc cgtgggcatt actgtttaag
     8701 acacttccgt cacatcccac cccatcctcc agggctcaac actgtgacat ctctattccc
     8761 caccctcccc ttcccagggc aataaaatga ccatggaggg ggcttgcact ctcttggctg
     8821 tcacccgatc gccagcaaaa cttagatgtg agaaaacccc ttcccattcc atggcgaaaa
     8881 catctcctta gaaaagccat taccctcatt aggcatggtt ttgggctccc aaaacacctg
     8941 acagcccctc cctcctctga gaggcggaga gtgctgactg tagtgaccat tgcatgccgg
     9001 gtgcagcatc tggaagagct aggcagggtg tctgccccct cctgagttga agtcatgctc
     9061 ccctgtgcca gcccagaggc cgagagctat ggacagcatt gccagtaaca caggccaccc
     9121 tgtgcagaag ggagctggct ccagcctgga aacctgtctg aggttgggag aggtgcactt
     9181 ggggcacagg gagaggccgg gacacactta gctggagatg tctctaaaag ccctgtatcg
     9241 tattcacctt cagtttttgt gttttgggac aattacttta gaaaataagt aggtcgtttt
     9301 aaaaacaaaa attattgatt gcttttttgt agtgttcaga aaaaaggttc tttgtgtata
     9361 gccaaatgac tgaaagcact gatatattta aaaacaaaag gcaatttatt aaggaaattt
     9421 gtaccatttc agtaaacctg tctgaatgta cctgtatacg tttcaaaaac accccccccc
     9481 cactgaatcc ctgtaaccta tttattatat aaagagtttg ccttataaat ttacataaaa
     9541 atgtccgttt gtgtcttttg ttgtaaaaat caagtgattt tttcataagg ttcttttact
     9601 attggaaaag atgggcagca cgcagtttta ttttattttt gtaagttttt taatacatgt
     9661 gaaagcaaag aatactcagc atgcctttct aagtgacgcg tttgcacctt ttgttgggaa
     9721 gtactgtatc ctgtgctgtt agcattctcg ataaatctct ctgtgaaagt ga
//
