LOCUS       NM_001397496             703 bp    mRNA    linear   PRI 08-APR-2024
DEFINITION  Homo sapiens MCTS family member 2 (MCTS2), mRNA.
ACCESSION   NM_001397496
VERSION     NM_001397496.1
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 703)
  AUTHORS   Kolarova,J., Tangen,I., Bens,S., Gillessen-Kaesbach,G., Gutwein,J.,
            Kautza,M., Rydzanicz,M., Stephani,U., Siebert,R., Ammerpohl,O. and
            Caliebe,A.
  TITLE     Array-based DNA methylation analysis in individuals with
            developmental delay/intellectual disability and normal molecular
            karyotype
  JOURNAL   Eur J Med Genet 58 (8), 419-425 (2015)
   PUBMED   26003415
REFERENCE   2  (bases 1 to 703)
  AUTHORS   Wood,A.J., Roberts,R.G., Monk,D., Moore,G.E., Schulz,R. and
            Oakey,R.J.
  TITLE     A screen for retrotransposed imprinted genes reveals an association
            between X chromosome homology and maternal germ-line methylation
  JOURNAL   PLoS Genet 3 (2), e20 (2007)
   PUBMED   17291163
REFERENCE   3  (bases 1 to 703)
  AUTHORS   Nandi,S., Shi,B., Perreault,J. and Gartenhaus,R.B.
  TITLE     Characterization of the MCT-1 pseudogene: identification and
            implication of its location in a highly amplified region of
            chromosome 20
  JOURNAL   Biochim Biophys Acta 1759 (5), 234-239 (2006)
   PUBMED   16815567
  REMARK    GeneRIF: A pseudogene for MCT-1 (PsiMCT-1) that is located on
            chromosome 20q11.2 was identified.
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL110115.38.
            
            Summary: This locus represents a retrogene copy of MCTS1
            (GeneID:28985) and contains an ORF similar to that parent gene.
            This locus is situated in a differentially methylated region (DMR)
            and transcripts in this region are imprinted. [provided by RefSeq,
            Nov 2021].
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript is intronless :: DR003643.1, AL538980.3 [ECO:0000345]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000394552.4/ ENSP00000496921.1
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-703               AL110115.38        20977-21679
FEATURES             Location/Qualifiers
     source          1..703
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="20"
                     /map="20q11.21"
     gene            1..703
                     /gene="MCTS2"
                     /gene_synonym="MCTS2P; PSIMCT-1"
                     /note="MCTS family member 2"
                     /db_xref="GeneID:100101490"
                     /db_xref="HGNC:HGNC:49760"
                     /db_xref="MIM:620406"
     exon            1..703
                     /gene="MCTS2"
                     /gene_synonym="MCTS2P; PSIMCT-1"
                     /inference="alignment:Splign:2.1.0"
     CDS             126..671
                     /gene="MCTS2"
                     /gene_synonym="MCTS2P; PSIMCT-1"
                     /note="malignant T cell amplified sequence 1 pseudogene;
                     malignant T cell amplified sequence 2, pseudogene; MCTS
                     family member 2, pseudogene"
                     /codon_start=1
                     /product="malignant T-cell-amplified sequence 2"
                     /protein_id="NP_001384425.1"
                     /db_xref="CCDS:CCDS93025.1"
                     /db_xref="GeneID:100101490"
                     /db_xref="HGNC:HGNC:49760"
                     /db_xref="MIM:620406"
                     /translation="MFKKFDEKESVSNCIQLKTSVIKGIKSQLVEQFPGIEPWLNQIM
                     PKKDPVKIVRCHEHTEILTVSGELLFFRQRKGPFCPTLRLLHKYPFILPHQQVDKGAI
                     KFVLSGANIMCPGLTSPGAKLYPAAVDTIVAVTAEGKQHALCVGVMKMSAEDIEKVNK
                     GIGIENIHYLNDGLWHMKTYK"
ORIGIN      
        1 agcgacaacg gctctgaccg tctggcaggc cgcgtggcgc ccgcgccggc cttcctgcag
       61 gggactccac cggagccttg ccaattccgt ttgtttccct gttgtcgccc gcttcaccct
      121 ggatcatgtt caagaagttt gatgaaaagg aaagtgtgtc caactgcatc cagttgaaaa
      181 cgtcagttat taagggcatt aagagccaac tggtagagca atttccaggt attgaaccat
      241 ggcttaatca aatcatgcct aagaaagatc ctgtcaaaat agtccgatgc cacgaacata
      301 cagaaatcct taccgtaagt ggggaattat tgttttttag acaaagaaag gggccttttt
      361 gtccaactct aaggttgctt cacaaatacc cttttatcct gccacaccag caggttgata
      421 aaggagctat caaatttgta ctcagtggcg caaatattat gtgtccaggt ttaacttctc
      481 ctggagctaa gctgtaccct gctgcagtag atacgattgt agcagtcaca gcggaaggaa
      541 aacagcatgc tctgtgtgtt ggggtcatga agatgtctgc agaagatatt gagaaagtca
      601 acaaaggaat tggcattgaa aatatccatt atttaaatga tgggctgtgg cacatgaaga
      661 catataaatg agcctcagaa ggaatgcatt tggggggcta aat
//
