LOCUS       XM_047430223            6502 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens MCF.2 cell line derived transforming
            sequence like (MCF2L), transcript variant X16, mRNA.
ACCESSION   XM_047430223
VERSION     XM_047430223.1
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000013.11) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6502
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="13"
     gene            1..6502
                     /gene="MCF2L"
                     /gene_synonym="ARHGEF14; DBS; OST"
                     /note="MCF.2 cell line derived transforming sequence like;
                     Derived by automated computational analysis using gene
                     prediction method: Gnomon. Supporting evidence includes
                     similarity to: 3 mRNAs, 78 ESTs, 586 long SRA reads, 3
                     Proteins, and 100% coverage of the annotated genomic
                     feature by RNAseq alignments, including 20 samples with
                     support for all annotated introns"
                     /db_xref="GeneID:23263"
                     /db_xref="HGNC:HGNC:14576"
                     /db_xref="MIM:609499"
     CDS             167..3619
                     /gene="MCF2L"
                     /gene_synonym="ARHGEF14; DBS; OST"
                     /codon_start=1
                     /product="guanine nucleotide exchange factor DBS isoform
                     X14"
                     /protein_id="XP_047286179.1"
                     /db_xref="GeneID:23263"
                     /db_xref="HGNC:HGNC:14576"
                     /db_xref="MIM:609499"
                     /translation="MRFWLRTEEMALEEMVQRLNAVSKHTDEIMHQDIVPLCAADIQD
                     QLKKRFAYLSGGRGQDGSPVITFPDYPAFSEIPDKEFQNVMTYLTSIPSLQDAGIGFI
                     LVIDRRRDKWTSVKASVLRIAASFPANLQLVLVLRPTGFFQRTLSDIAFKFNRDDFKM
                     KVPVIMLSSVPDLHGYIDKSQLTEDLGGTLDYCHSRWLCQRTAIESFALMVKQTAQML
                     QSFGTELAETELPNDVQSTSSVLCAHTEKKDKAKEDLRLALKEGHSVLESLRELQAEG
                     SEPSVNQDQLDNQATVQRLLAQLNETEAAFDEFWAKHQQKLEQCLQLRHFEQGFREVK
                     AILDAASQKIATFTDIGNSLAHVEHLLRDLASFEEKSGVAVERARALSLDGEQLIGNK
                     HYAVDSIRPKCQELRHLCDQFSAEIARRRGLLSKSLELHRRLETSMKWCDEGIYLLAS
                     QPVDKCQSQDGAEAALQEIEKFLETGAENKIQELNAIYKEYESILNQDLMEHVRKVFQ
                     KQASMEEVFHRRQASLKKLAARQTRPVQPVAPRPEALAKSPCPSPGIRRGSENSSSEG
                     GALRRGPYRRAKSEMSESRQGRGSAGEEEESLAILRRHVMSELLDTERAYVEELLCVL
                     EGYAAEMDNPLMAHLLSTGLHNKKDVLFGNMEEIYHFHNRIFLRELENYTDCPELVGR
                     CFLERMEDFQIYEKYCQNKPRSESLWRQCSDCPFFQECQRKLDHKLSLDSYLLKPVQR
                     ITKYQLLLKEMLKYSRNCEGAEDLQEALSSILGILKAVNDSMHLIAITGYDGNLGDLG
                     KLLMQGSFSVWTDHKRGHTKVKELARFKPMQRHLFLHEKAVLFCKKREENGEGYEKAP
                     SYSYKQSLNMAAVGITENVKGDAKKFEIWYNAREEVYIVQAPTPEIKAAWVNEIRKVL
                     TSQLQACREASQHRALEQSQSLPLPAPTSTSPSRGNSRNIKKLEERKTDPLSLEGYVS
                     SAPLTKPPEKGKASPTSPDKKAKRHEVKSDPTPFGVRGWSKTSHSLEAPEDDGGWSSA
                     EEQINSSDAEEDGGLGPKKLVPGKYTVVADHEKGGPDALRVRSGDVVELVQEGDEGLW
                     YVRDPTTGKEGWVPASSLSVRLGPSGSAQCLSSSESSPGSAVLSNSSSCSEGGQAPFS
                     DLQG"
ORIGIN      
        1 gcggaaccaa tcctgggcag ggaggcggcg gctggaggct gaaagcgctg ccgtggcccc
       61 ctccccgcct ccgccgcgcc ccctccgcac tcgcacggcc ccacccgcag gcgccccccg
      121 tgcggaggaa gcggatctgc caggatcatt tttgttgtgt cggaggatga ggttttggct
      181 gaggactgaa gagatggcct tggaagaaat ggtgcagaga ttaaatgcgg tttccaagca
      241 cacggatgaa atcatgcacc aggacatcgt cccgctctgt gctgccgaca tccaggacca
      301 gctaaagaag cgctttgctt acctgtccgg tgggcggggg caggacggaa gcccggttat
      361 caccttccct gactacccgg ccttcagcga gattccggac aaggagttcc agaatgtcat
      421 gacctacctc accagcatcc ccagcctgca ggacgctggc atcggattca tcctggtgat
      481 agaccggcga cgggacaaat ggacctccgt gaaggcgtcc gtcctgcgca tcgcagcatc
      541 tttcccggca aacctgcagc tcgtcctcgt gcttcgcccg acgggttttt tccaaaggac
      601 tctctccgac atcgctttca aattcaatag agatgacttt aagatgaagg tgccggtcat
      661 aatgctgagc tccgtaccag acttacacgg ttacatcgat aagtcgcagc tgaccgagga
      721 cctgggtggg accctggact actgccactc ccggtggctg tgccagcgca cggccatcga
      781 aagtttcgcc ctcatggtga agcagacggc tcagatgctg cagtccttcg ggaccgagct
      841 ggctgaaaca gagctgccca atgacgtcca gtcgacaagc tcagtgctgt gtgcgcacac
      901 agagaagaag gacaaggcga aggaggattt gaggctggca ctgaaagagg ggcacagtgt
      961 cctggagagc ctcagggagc tgcaggctga gggctcagag cccagtgtga accaggacca
     1021 gcttgacaac caggccaccg tgcagaggct cctggcccag ctgaacgaaa ccgaggctgc
     1081 cttcgatgag ttctgggcaa agcatcagca gaaactggag cagtgtctgc agctccggca
     1141 ctttgagcag ggcttccggg aggtcaaagc catcttggac gcagcgtccc agaagatagc
     1201 aaccttcaca gacatcggca acagcctggc gcatgtggag cacctgctga gggacctggc
     1261 cagcttcgag gagaaatcag gcgtggccgt ggagagggcc cgggccctgt ctctggacgg
     1321 cgagcagctc attgggaaca agcactacgc ggtagactcc atccgcccaa agtgccagga
     1381 gctccggcac ctctgtgacc agttctctgc ggagatcgca aggaggaggg ggctgctcag
     1441 caagtccctg gagctgcacc gccgcctgga gacgtccatg aagtggtgtg atgaagggat
     1501 ttacctgctg gcctcacaac ctgtggacaa gtgccagtcc caggacggcg cggaggctgc
     1561 cctccaggaa atcgagaagt ttttggagac cggtgcggaa aataagatcc aggagctcaa
     1621 cgcgatttac aaggaatacg aatccatcct caaccaagat ctcatggagc acgtgcgaaa
     1681 ggtcttccag aagcaggcaa gcatggagga ggtgttccac cgcaggcagg ccagcctgaa
     1741 gaagctggcg gccaggcaga cgcggcccgt gcagccggtg gcccccagac ccgaggcact
     1801 ggcaaagtcg ccctgcccct ccccaggcat tcggcgaggc tctgagaact ccagctccga
     1861 gggcggtgcg ctccggagag ggccctaccg gagggccaag agtgagatga gtgagagccg
     1921 gcagggccgc ggctcagcgg gggaggagga ggaaagcctg gccatcctgc gcaggcacgt
     1981 gatgagcgag ctcctggaca cagaacgggc ctacgtggag gagctgctgt gcgtcctgga
     2041 gggctacgcc gcggagatgg ataacccact gatggctcac ctcctgtcaa caggccttca
     2101 caacaagaag gatgttttgt ttggaaacat ggaggaaatc tatcacttcc acaacaggat
     2161 attcctcagg gagctggaaa actacactga ctgcccagaa ctggttggaa gatgctttct
     2221 ggagaggatg gaagatttcc agatctatga gaagtactgt cagaacaagc cccgctctga
     2281 gagcctgtgg agacagtgct ccgactgccc gtttttccag gaatgccaga gaaagctgga
     2341 ccacaagctg agcctggact cctacctgct gaagccagtg cagaggatca ccaagtacca
     2401 gctgctgctc aaggaaatgc tgaaatacag caggaactgc gagggggctg aggacctgca
     2461 ggaggcgctg agctccatcc tgggcatcct gaaggccgtg aacgactcca tgcacctcat
     2521 cgctatcacc ggctatgacg ggaatctcgg cgacctgggc aagctgctga tgcagggctc
     2581 gttcagcgtc tggaccgacc acaagagggg ccacaccaag gtgaaggagc tggccaggtt
     2641 caagcccatg cagcggcacc tgttcctgca cgagaaggca gtgctcttct gcaagaagag
     2701 ggaggagaat ggggaggggt atgagaaagc tccctcctac agctacaagc agtccttaaa
     2761 catggctgcc gttggcatta cggagaacgt gaagggagat gctaagaagt tcgagatctg
     2821 gtacaacgcg cgcgaggagg tctacatcgt ccaggcgcca actcctgaga ttaaagccgc
     2881 gtgggtgaat gaaattcgga aagtgctgac cagccagctg caggcttgta gagaagccag
     2941 ccagcaccgg gcgctggagc agtcacagag cctgcccctg ccggccccga ccagcaccag
     3001 tccctcaaga ggaaactcaa ggaacatcaa gaagctggaa gaaaggaaaa cagaccccct
     3061 aagcctggag ggatacgtca gctcagcgcc actgacaaag ccccccgaaa agggcaaagc
     3121 ttctcctacc agtcctgaca aaaaagccaa gcggcatgaa gtaaagagcg acccgactcc
     3181 ctttggtgtg cgaggttgga gcaaaacgtc ccactcactg gaggcacctg aggacgacgg
     3241 gggctggtca agtgcagagg agcagattaa ctcgtccgac gcagaggagg acggcgggtt
     3301 gggccccaag aagctggttc caggtaaata cacggtcgtg gcggaccacg agaagggagg
     3361 ccccgatgcg ctgcgcgtga ggagcgggga cgtggtggag ctggtgcagg agggcgacga
     3421 gggcctctgg tacgtcaggg acccgaccac tggcaaggag ggctgggtgc cggccagcag
     3481 cctgtccgtc cggctcggcc cgtccggctc ggcccagtgc ctgagcagct cagagtcgag
     3541 cccggggtcg gccgtgctga gcaactcgtc cagctgcagc gagggcggcc aggccccctt
     3601 ctccgacctg caggggtagc gcggcctcgg cgccggagac ccgcgcgctg tctggggctg
     3661 cggtggcgtg gggagggcgc ggcccccgga cgccccgagg aaggggcacc tcaccgcccc
     3721 cacccagagc gcctggccgt gcgggctgca gaggacccct ccggggcaga ggcaggttcc
     3781 acggaagacc ccggcccgct ggggcttccc cggagactcc agagcccaca gaggaggggc
     3841 cgcagggaac agccccgggc ggcaggcgcc gggcagcggc atctcgtcct ggctccaccg
     3901 tgctgcttct gcctctggac ggtgctttca ggggacgcgc ggaccgtggt ggagctgctt
     3961 ccggagaagt ggaggatcct ctggccaacg gcctgaggag agcggggcac ggggtctctt
     4021 tagcttttac aagttttagg attttttcaa gcagggatca atcccgtggc cattttttgt
     4081 ggtactttgg cctcaattct tcaccaggaa tcactgtgtt tacatgaaat gacaatttga
     4141 tactgtattt gatagaaaac tatttttttg ttaccggggt ttacatagaa gcacgttgtt
     4201 tataccacta agtgactttg ggggggctct cccatggaaa cggatggcac tccctgaagc
     4261 tccctggtca caggtggatg aaaacgtgtc cgtgggtgac atcaggtggt gtctccacca
     4321 ccaaaagcag ttagaagcca aggagattcc tttatctacc tagggttcat tttcaaaaga
     4381 aaatttaaac tataatttaa acaattaacg ttcttttcta caaaaaaaat gcagggactt
     4441 gattttttta aagagcttca ctgaattagg atatttttat tgcttttaaa gaaaatacaa
     4501 agatgcagtt tctgcagggt gtggcgtgga ccagtgctgc cgaccatagc tcagagagcc
     4561 ctgcccctgc ctcactgcac tgcagcctcc tcggaggccg cacctccact ccactcccca
     4621 cgcgccccct gcctcccacc caggtccacc tgccacctgg tgaccacctt gagtacagaa
     4681 gtgaaagtgg ggagagtatt ttattcaagt cacagcagaa ctggaaaaaa actcttctgt
     4741 tttaccaact tcttgtgttt cagaaacata ttctgttcaa aacttttgaa gccctttcgg
     4801 tgtctagtct gcagatgttt ttgtatgtgt gcacctctga ccatgtgtgt acatatgtgt
     4861 cttgctggaa aggacatatt cgctgtcccc gtgctgctgg gagggccgcc tcacagcctc
     4921 acggttccca gccccagcac agtggaggca ggcgtggctg cattcccctc acgctaccct
     4981 cccagcggct tgtagccgtc actggccaga cctccagggt gcggaatcaa ataggaagca
     5041 tgcagagact cggcagcttt tcctctgatg tgtaagttat ttggaacgcg tgctgtgtcc
     5101 cgcgatgtcc ctgatgtact gtgcaggcgc ggtgcctccg tctcgtcgca cagctgcgcg
     5161 cccttgtgtg accctcccca taaaggcact ttacagcttc atgtttcatc cactgtcact
     5221 tttttttaac tgctgatgta aatggaattt taaaagcaga gttctttatt gtatggatga
     5281 cgtttgaata aatatcagca actcctgcca tctgcctttg tctgtcaaga cacagaacgt
     5341 ctcagcagtc ggggtttcca gggccgcagt gcactgtgct tgcacatggt aagtcattgt
     5401 tgggacggaa aagaagccgg cagtgggcag ggcccagcgt gcggctcagg caccgagcaa
     5461 ccgctttgct ttcttctgtc agacggcgat gatgacaaaa tagcaacaag gttgtgcgtg
     5521 tcagaaacgc aaaggcagca gaggaagcgt agtggaacca ttacagaatc acaatgcagc
     5581 cgacactctc cagaccagaa aagggagcat aaagaaaggg tattgatcca atagaagaag
     5641 ggaagggtgg agaaagggga aagcatggtt aacaggaaac aacatgtaac ggaagagaca
     5701 gcccagatgt gtctggctca caacagacgt gatcatgtta tgctggcctg gaagagcatc
     5761 ggatcagacg tgacaagtca ctgcttagag accatcaagc aaatttatat atagattgga
     5821 gatttaaaat aaaagaagac agaacagaca aacaccataa gaaagctggt gtagcagtat
     5881 cgatgacctg aaatgggatt caggacagtt catagagtaa agggggctgc gtggcaatca
     5941 ggaactcata agccactgac tataaagctc aaaacacagc aaagttggca gtcggcagac
     6001 agcaatgttg actgtcatga aaagtgatcc ctgtttgccc ctaaacgtag agaaatctgc
     6061 gttattttcc agcacacatg gagcacaaac aaaatatttg caaaacaatg ggaagatcat
     6121 tgaaacactg tttggcaatt taaaagcttg tttctaactc acgggatgcg ggcagtctgc
     6181 tctctagaac tggacagcgt gcacagagcc acgggaggga gcagccacgg ccagctcaga
     6241 ttggtgtcga cagcttagtg gtgtctgatt ttatacatga caaaatgaac gagttaacca
     6301 tttaagccaa aaaaataaga ctagcgtaac ccaaagaaag tatttaaata cttctgtcaa
     6361 ttaggacagt tgagaaaaga gaataacaaa atcaaaagca aaactcaaac tttgtacctg
     6421 aaaaatctaa taaaactgac taatttatag aaaacctaag aaactccata tcaaataaaa
     6481 aattttaaat atgagagaac ca
//
