LOCUS       XM_011537485            6595 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens MCF.2 cell line derived transforming
            sequence like (MCF2L), transcript variant X8, mRNA.
ACCESSION   XM_011537485
VERSION     XM_011537485.2
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000013.11) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Apr 5, 2022 this sequence version replaced XM_011537485.1.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6595
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="13"
     gene            1..6595
                     /gene="MCF2L"
                     /gene_synonym="ARHGEF14; DBS; OST"
                     /note="MCF.2 cell line derived transforming sequence like;
                     Derived by automated computational analysis using gene
                     prediction method: Gnomon. Supporting evidence includes
                     similarity to: 3 mRNAs, 76 ESTs, 572 long SRA reads, 4
                     Proteins, and 100% coverage of the annotated genomic
                     feature by RNAseq alignments, including 4 samples with
                     support for all annotated introns"
                     /db_xref="GeneID:23263"
                     /db_xref="HGNC:HGNC:14576"
                     /db_xref="MIM:609499"
     CDS             167..3712
                     /gene="MCF2L"
                     /gene_synonym="ARHGEF14; DBS; OST"
                     /codon_start=1
                     /product="guanine nucleotide exchange factor DBS isoform
                     X7"
                     /protein_id="XP_011535787.1"
                     /db_xref="GeneID:23263"
                     /db_xref="HGNC:HGNC:14576"
                     /db_xref="MIM:609499"
                     /translation="MRFWLRTEEMALEEMVQRLNAVSKHTDEIMHQDIVPLCAADIQD
                     QLKKRFAYLSGGRGQDGSPVITFPDYPAFSEIPDKEFQNVMTYLTSIPSLQDAGIGFI
                     LVIDRRRDKWTSVKASVLRIAASFPANLQLVLVLRPTGFFQRTLSDIAFKFNRDDFKM
                     KVPVIMLSSVPDLHGYIDKSQLTEDLGGTLDYCHSRWLCQRTAIESFALMVKQTAQML
                     QSFGTELAETELPNDVQSTSSVLCAHTEKKDKAKEDLRLALKEGHSVLESLRELQAEG
                     SEPSVNQDQLDNQATVQRLLAQLNETEAAFDEFWAKHQQKLEQCLQLRHFEQGFREVK
                     AILDAASQKIATFTDIGNSLAHVEHLLRDLASFEEKSGVAVERARALSLDGEQLIGNK
                     HYAVDSIRPKCQELRHLCDQFSAEIARRRGLLSKSLELHRRLETSMKWCDEGIYLLAS
                     QPVDKCQSQDGAEAALQEIEKFLETGAENKIQELNAIYKEYESILNQDLMEHVRKVFQ
                     KQASMEEVFHRRQASLKKLAARQTRPVQPVAPRPEALAKSPCPSPGIRRGSENSSSEG
                     GALRRGPYRRAKSEMSESRQGRGSAGEEEESLAILRRHVMSELLDTERAYVEELLCVL
                     EGYAAEMDNPLMAHLLSTGLHNKKDVLFGNMEEIYHFHNRIFLRELENYTDCPELVGR
                     CFLERMEDFQIYEKYCQNKPRSESLWRQCSDCPFFQECQRKLDHKLSLDSYLLKPVQR
                     ITKYQLLLKEMLKYSRNCEGAEDLQEALSSILGILKAVNDSMHLIAITGYDGNLGDLG
                     KLLMQGSFSVWTDHKRGHTKVKELARFKPMQRHLFLHEKAVLFCKKREENGEGYEKAP
                     SYSYKQSLNMAAVGITENVKGDAKKFEIWYNAREEVYIVQAPTPEIKAAWVNEIRKVL
                     TSQLQACREASQHRALEQSQSLPLPAPTSTSPSRGNSRNIKKLEERKTDPLSLEGYVS
                     SAPLTKPPEKGKDDTVTSSASESSALSRKRFTLQGFANLKGQKASPTSPDKKAKRHEV
                     KSDPTPFGVRGWSKTSHSLEAPEDDGGWSSAEEQINSSDAEEDGGLGPKKLVPGKYTV
                     VADHEKGGPDALRVRSGDVVELVQEGDEGLWYVRDPTTGKEGWVPASSLSVRLGPSGS
                     AQCLSSSESSPGSAVLSNSSSCSEGGQAPFSDLQG"
ORIGIN      
        1 gcggaaccaa tcctgggcag ggaggcggcg gctggaggct gaaagcgctg ccgtggcccc
       61 ctccccgcct ccgccgcgcc ccctccgcac tcgcacggcc ccacccgcag gcgccccccg
      121 tgcggaggaa gcggatctgc caggatcatt tttgttgtgt cggaggatga ggttttggct
      181 gaggactgaa gagatggcct tggaagaaat ggtgcagaga ttaaatgcgg tttccaagca
      241 cacggatgaa atcatgcacc aggacatcgt cccgctctgt gctgccgaca tccaggacca
      301 gctaaagaag cgctttgctt acctgtccgg tgggcggggg caggacggaa gcccggttat
      361 caccttccct gactacccgg ccttcagcga gattccggac aaggagttcc agaatgtcat
      421 gacctacctc accagcatcc ccagcctgca ggacgctggc atcggattca tcctggtgat
      481 agaccggcga cgggacaaat ggacctccgt gaaggcgtcc gtcctgcgca tcgcagcatc
      541 tttcccggca aacctgcagc tcgtcctcgt gcttcgcccg acgggttttt tccaaaggac
      601 tctctccgac atcgctttca aattcaatag agatgacttt aagatgaagg tgccggtcat
      661 aatgctgagc tccgtaccag acttacacgg ttacatcgat aagtcgcagc tgaccgagga
      721 cctgggtggg accctggact actgccactc ccggtggctg tgccagcgca cggccatcga
      781 aagtttcgcc ctcatggtga agcagacggc tcagatgctg cagtccttcg ggaccgagct
      841 ggctgaaaca gagctgccca atgacgtcca gtcgacaagc tcagtgctgt gtgcgcacac
      901 agagaagaag gacaaggcga aggaggattt gaggctggca ctgaaagagg ggcacagtgt
      961 cctggagagc ctcagggagc tgcaggctga gggctcagag cccagtgtga accaggacca
     1021 gcttgacaac caggccaccg tgcagaggct cctggcccag ctgaacgaaa ccgaggctgc
     1081 cttcgatgag ttctgggcaa agcatcagca gaaactggag cagtgtctgc agctccggca
     1141 ctttgagcag ggcttccggg aggtcaaagc catcttggac gcagcgtccc agaagatagc
     1201 aaccttcaca gacatcggca acagcctggc gcatgtggag cacctgctga gggacctggc
     1261 cagcttcgag gagaaatcag gcgtggccgt ggagagggcc cgggccctgt ctctggacgg
     1321 cgagcagctc attgggaaca agcactacgc ggtagactcc atccgcccaa agtgccagga
     1381 gctccggcac ctctgtgacc agttctctgc ggagatcgca aggaggaggg ggctgctcag
     1441 caagtccctg gagctgcacc gccgcctgga gacgtccatg aagtggtgtg atgaagggat
     1501 ttacctgctg gcctcacaac ctgtggacaa gtgccagtcc caggacggcg cggaggctgc
     1561 cctccaggaa atcgagaagt ttttggagac cggtgcggaa aataagatcc aggagctcaa
     1621 cgcgatttac aaggaatacg aatccatcct caaccaagat ctcatggagc acgtgcgaaa
     1681 ggtcttccag aagcaggcaa gcatggagga ggtgttccac cgcaggcagg ccagcctgaa
     1741 gaagctggcg gccaggcaga cgcggcccgt gcagccggtg gcccccagac ccgaggcact
     1801 ggcaaagtcg ccctgcccct ccccaggcat tcggcgaggc tctgagaact ccagctccga
     1861 gggcggtgcg ctccggagag ggccctaccg gagggccaag agtgagatga gtgagagccg
     1921 gcagggccgc ggctcagcgg gggaggagga ggaaagcctg gccatcctgc gcaggcacgt
     1981 gatgagcgag ctcctggaca cagaacgggc ctacgtggag gagctgctgt gcgtcctgga
     2041 gggctacgcc gcggagatgg ataacccact gatggctcac ctcctgtcaa caggccttca
     2101 caacaagaag gatgttttgt ttggaaacat ggaggaaatc tatcacttcc acaacaggat
     2161 attcctcagg gagctggaaa actacactga ctgcccagaa ctggttggaa gatgctttct
     2221 ggagaggatg gaagatttcc agatctatga gaagtactgt cagaacaagc cccgctctga
     2281 gagcctgtgg agacagtgct ccgactgccc gtttttccag gaatgccaga gaaagctgga
     2341 ccacaagctg agcctggact cctacctgct gaagccagtg cagaggatca ccaagtacca
     2401 gctgctgctc aaggaaatgc tgaaatacag caggaactgc gagggggctg aggacctgca
     2461 ggaggcgctg agctccatcc tgggcatcct gaaggccgtg aacgactcca tgcacctcat
     2521 cgctatcacc ggctatgacg ggaatctcgg cgacctgggc aagctgctga tgcagggctc
     2581 gttcagcgtc tggaccgacc acaagagggg ccacaccaag gtgaaggagc tggccaggtt
     2641 caagcccatg cagcggcacc tgttcctgca cgagaaggca gtgctcttct gcaagaagag
     2701 ggaggagaat ggggaggggt atgagaaagc tccctcctac agctacaagc agtccttaaa
     2761 catggctgcc gttggcatta cggagaacgt gaagggagat gctaagaagt tcgagatctg
     2821 gtacaacgcg cgcgaggagg tctacatcgt ccaggcgcca actcctgaga ttaaagccgc
     2881 gtgggtgaat gaaattcgga aagtgctgac cagccagctg caggcttgta gagaagccag
     2941 ccagcaccgg gcgctggagc agtcacagag cctgcccctg ccggccccga ccagcaccag
     3001 tccctcaaga ggaaactcaa ggaacatcaa gaagctggaa gaaaggaaaa cagaccccct
     3061 aagcctggag ggatacgtca gctcagcgcc actgacaaag ccccccgaaa agggcaaaga
     3121 tgacacggtc actagctctg cctcagaaag ctctgcgctt tccagaaagc gctttaccct
     3181 gcagggtttt gctaacctca aaggtcagaa agcttctcct accagtcctg acaaaaaagc
     3241 caagcggcat gaagtaaaga gcgacccgac tccctttggt gtgcgaggtt ggagcaaaac
     3301 gtcccactca ctggaggcac ctgaggacga cgggggctgg tcaagtgcag aggagcagat
     3361 taactcgtcc gacgcagagg aggacggcgg gttgggcccc aagaagctgg ttccaggtaa
     3421 atacacggtc gtggcggacc acgagaaggg aggccccgat gcgctgcgcg tgaggagcgg
     3481 ggacgtggtg gagctggtgc aggagggcga cgagggcctc tggtacgtca gggacccgac
     3541 cactggcaag gagggctggg tgccggccag cagcctgtcc gtccggctcg gcccgtccgg
     3601 ctcggcccag tgcctgagca gctcagagtc gagcccgggg tcggccgtgc tgagcaactc
     3661 gtccagctgc agcgagggcg gccaggcccc cttctccgac ctgcaggggt agcgcggcct
     3721 cggcgccgga gacccgcgcg ctgtctgggg ctgcggtggc gtggggaggg cgcggccccc
     3781 ggacgccccg aggaaggggc acctcaccgc ccccacccag agcgcctggc cgtgcgggct
     3841 gcagaggacc cctccggggc agaggcaggt tccacggaag accccggccc gctggggctt
     3901 ccccggagac tccagagccc acagaggagg ggccgcaggg aacagccccg ggcggcaggc
     3961 gccgggcagc ggcatctcgt cctggctcca ccgtgctgct tctgcctctg gacggtgctt
     4021 tcaggggacg cgcggaccgt ggtggagctg cttccggaga agtggaggat cctctggcca
     4081 acggcctgag gagagcgggg cacggggtct ctttagcttt tacaagtttt aggatttttt
     4141 caagcaggga tcaatcccgt ggccattttt tgtggtactt tggcctcaat tcttcaccag
     4201 gaatcactgt gtttacatga aatgacaatt tgatactgta tttgatagaa aactattttt
     4261 ttgttaccgg ggtttacata gaagcacgtt gtttatacca ctaagtgact ttgggggggc
     4321 tctcccatgg aaacggatgg cactccctga agctccctgg tcacaggtgg atgaaaacgt
     4381 gtccgtgggt gacatcaggt ggtgtctcca ccaccaaaag cagttagaag ccaaggagat
     4441 tcctttatct acctagggtt cattttcaaa agaaaattta aactataatt taaacaatta
     4501 acgttctttt ctacaaaaaa aatgcaggga cttgattttt ttaaagagct tcactgaatt
     4561 aggatatttt tattgctttt aaagaaaata caaagatgca gtttctgcag ggtgtggcgt
     4621 ggaccagtgc tgccgaccat agctcagaga gccctgcccc tgcctcactg cactgcagcc
     4681 tcctcggagg ccgcacctcc actccactcc ccacgcgccc cctgcctccc acccaggtcc
     4741 acctgccacc tggtgaccac cttgagtaca gaagtgaaag tggggagagt attttattca
     4801 agtcacagca gaactggaaa aaaactcttc tgttttacca acttcttgtg tttcagaaac
     4861 atattctgtt caaaactttt gaagcccttt cggtgtctag tctgcagatg tttttgtatg
     4921 tgtgcacctc tgaccatgtg tgtacatatg tgtcttgctg gaaaggacat attcgctgtc
     4981 cccgtgctgc tgggagggcc gcctcacagc ctcacggttc ccagccccag cacagtggag
     5041 gcaggcgtgg ctgcattccc ctcacgctac cctcccagcg gcttgtagcc gtcactggcc
     5101 agacctccag ggtgcggaat caaataggaa gcatgcagag actcggcagc ttttcctctg
     5161 atgtgtaagt tatttggaac gcgtgctgtg tcccgcgatg tccctgatgt actgtgcagg
     5221 cgcggtgcct ccgtctcgtc gcacagctgc gcgcccttgt gtgaccctcc ccataaaggc
     5281 actttacagc ttcatgtttc atccactgtc actttttttt aactgctgat gtaaatggaa
     5341 ttttaaaagc agagttcttt attgtatgga tgacgtttga ataaatatca gcaactcctg
     5401 ccatctgcct ttgtctgtca agacacagaa cgtctcagca gtcggggttt ccagggccgc
     5461 agtgcactgt gcttgcacat ggtaagtcat tgttgggacg gaaaagaagc cggcagtggg
     5521 cagggcccag cgtgcggctc aggcaccgag caaccgcttt gctttcttct gtcagacggc
     5581 gatgatgaca aaatagcaac aaggttgtgc gtgtcagaaa cgcaaaggca gcagaggaag
     5641 cgtagtggaa ccattacaga atcacaatgc agccgacact ctccagacca gaaaagggag
     5701 cataaagaaa gggtattgat ccaatagaag aagggaaggg tggagaaagg ggaaagcatg
     5761 gttaacagga aacaacatgt aacggaagag acagcccaga tgtgtctggc tcacaacaga
     5821 cgtgatcatg ttatgctggc ctggaagagc atcggatcag acgtgacaag tcactgctta
     5881 gagaccatca agcaaattta tatatagatt ggagatttaa aataaaagaa gacagaacag
     5941 acaaacacca taagaaagct ggtgtagcag tatcgatgac ctgaaatggg attcaggaca
     6001 gttcatagag taaagggggc tgcgtggcaa tcaggaactc ataagccact gactataaag
     6061 ctcaaaacac agcaaagttg gcagtcggca gacagcaatg ttgactgtca tgaaaagtga
     6121 tccctgtttg cccctaaacg tagagaaatc tgcgttattt tccagcacac atggagcaca
     6181 aacaaaatat ttgcaaaaca atgggaagat cattgaaaca ctgtttggca atttaaaagc
     6241 ttgtttctaa ctcacgggat gcgggcagtc tgctctctag aactggacag cgtgcacaga
     6301 gccacgggag ggagcagcca cggccagctc agattggtgt cgacagctta gtggtgtctg
     6361 attttataca tgacaaaatg aacgagttaa ccatttaagc caaaaaaata agactagcgt
     6421 aacccaaaga aagtatttaa atacttctgt caattaggac agttgagaaa agagaataac
     6481 aaaatcaaaa gcaaaactca aactttgtac ctgaaaaatc taataaaact gactaattta
     6541 tagaaaacct aagaaactcc atatcaaata aaaaatttta aatatgagag aacca
//
