LOCUS       NM_138799               7622 bp    mRNA    linear   PRI 02-FEB-2025
DEFINITION  Homo sapiens membrane bound glycerophospholipid O-acyltransferase 2
            (MBOAT2), transcript variant 1, mRNA.
ACCESSION   NM_138799 XM_938724
VERSION     NM_138799.4
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 7622)
  AUTHORS   Yu,X., Tong,H., Chen,J., Tang,C., Wang,S., Si,Y., Wang,S. and
            Tang,Z.
  TITLE     CircRNA MBOAT2 promotes intrahepatic cholangiocarcinoma progression
            and lipid metabolism reprogramming by stabilizing PTBP1 to
            facilitate FASN mRNA cytoplasmic export
  JOURNAL   Cell Death Dis 14 (1), 20 (2023)
   PUBMED   36635270
  REMARK    GeneRIF: CircRNA MBOAT2 promotes intrahepatic cholangiocarcinoma
            progression and lipid metabolism reprogramming by stabilizing PTBP1
            to facilitate FASN mRNA cytoplasmic export.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7622)
  AUTHORS   Zhou,X., Liu,K., Cui,J., Xiong,J., Wu,H., Peng,T. and Guo,Y.
  TITLE     Circ-MBOAT2 knockdown represses tumor progression and glutamine
            catabolism by miR-433-3p/GOT1 axis in pancreatic cancer
  JOURNAL   J Exp Clin Cancer Res 40 (1), 124 (2021)
   PUBMED   33832516
  REMARK    GeneRIF: Circ-MBOAT2 knockdown represses tumor progression and
            glutamine catabolism by miR-433-3p/GOT1 axis in pancreatic cancer.
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 7622)
  AUTHORS   Gijon,M.A., Riekhof,W.R., Zarini,S., Murphy,R.C. and Voelker,D.R.
  TITLE     Lysophospholipid acyltransferases and arachidonate recycling in
            human neutrophils
  JOURNAL   J Biol Chem 283 (44), 30235-30245 (2008)
   PUBMED   18772128
REFERENCE   4  (bases 1 to 7622)
  AUTHORS   Tamaki,H., Shimada,A., Ito,Y., Ohya,M., Takase,J., Miyashita,M.,
            Miyagawa,H., Nozaki,H., Nakayama,R. and Kumagai,H.
  TITLE     LPT1 encodes a membrane-bound O-acyltransferase involved in the
            acylation of lysophospholipids in the yeast Saccharomyces
            cerevisiae
  JOURNAL   J Biol Chem 282 (47), 34288-34298 (2007)
   PUBMED   17890783
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC112723.3 and AC012495.9.
            
            On Nov 23, 2018 this sequence version replaced NM_138799.3.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1803617.166388.1,
                                           SRR1803613.131308.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA1965299,
                                           SAMEA1966682 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000305997.8/ ENSP00000302177.3
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-145               AC112723.3         66392-66536         c
            146-291             AC112723.3         21349-21494         c
            292-369             AC112723.3         6039-6116           c
            370-465             AC012495.9         184833-184928       c
            466-521             AC012495.9         164230-164285       c
            522-576             AC012495.9         158723-158777       c
            577-760             AC012495.9         153242-153425       c
            761-953             AC012495.9         149320-149512       c
            954-1057            AC012495.9         144658-144761       c
            1058-1122           AC012495.9         140382-140446       c
            1123-1255           AC012495.9         138802-138934       c
            1256-1407           AC012495.9         136825-136976       c
            1408-7622           AC012495.9         128902-135116       c
FEATURES             Location/Qualifiers
     source          1..7622
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="2"
                     /map="2p25.1"
     gene            1..7622
                     /gene="MBOAT2"
                     /gene_synonym="LPAAT; LPCAT; LPCAT4; LPEAT; LPLAT 2;
                     LPLAT13; OACT2"
                     /note="membrane bound glycerophospholipid
                     O-acyltransferase 2"
                     /db_xref="GeneID:129642"
                     /db_xref="HGNC:HGNC:25193"
                     /db_xref="MIM:611949"
     exon            1..145
                     /gene="MBOAT2"
                     /gene_synonym="LPAAT; LPCAT; LPCAT4; LPEAT; LPLAT 2;
                     LPLAT13; OACT2"
                     /inference="alignment:Splign:2.1.0"
     CDS             71..1633
                     /gene="MBOAT2"
                     /gene_synonym="LPAAT; LPCAT; LPCAT4; LPEAT; LPLAT 2;
                     LPLAT13; OACT2"
                     /EC_number="2.3.1.51"
                     /EC_number="2.3.1.23"
                     /EC_number="2.3.1.n7"
                     /note="isoform 1 is encoded by transcript variant 1;
                     O-acyltransferase (membrane bound) domain containing 2;
                     lysophospholipid acyltransferase 2; lyso-PA
                     acyltransferase; lyso-PE acyltransferase; membrane bound
                     O-acyltransferase domain containing 2; lysophosphatidic
                     acid acyltransferase; 1-acylglycerophosphate
                     O-acyltransferase; lysophosphatidylethanolamine
                     acyltransferase; 1-acylglycerophosphoethanolamine
                     O-acyltransferase; membrane-bound O-acyltransferase
                     domain-containing protein 2; lyso-PC acyltransferase;
                     lyso-PC acyltransferase 4; lysophospholipid
                     acyltransferase 13; lysophosphatidylcholine
                     acyltransferase; lysophosphatidylcholine acyltransferase
                     4; 1-acylglycerophosphate O-acyltransferase MBOAT2;
                     1-acylglycerophosphocholine O-acyltransferase MBOAT2;
                     1-acylglycerophosphoethanolamine MBOAT2 O-acyltransferase"
                     /codon_start=1
                     /product="lysophospholipid acyltransferase 2 isoform 1"
                     /protein_id="NP_620154.2"
                     /db_xref="CCDS:CCDS1660.1"
                     /db_xref="GeneID:129642"
                     /db_xref="HGNC:HGNC:25193"
                     /db_xref="MIM:611949"
                     /translation="MATTSTTGSTLLQPLSNAVQLPIDQVNFVVCQLFALLAAIWFRT
                     YLHSSKTSSFIRHVVATLLGLYLALFCFGWYALHFLVQSGISYCIMIIIGVENMHNYC
                     FVFALGYLTVCQVTRVYIFDYGQYSADFSGPMMIITQKITSLACEIHDGMFRKDEELT
                     SSQRDLAVRRMPSLLEYLSYNCNFMGILAGPLCSYKDYITFIEGRSYHITQSGENGKE
                     ETQYERTEPSPNTAVVQKLLVCGLSLLFHLTICTTLPVEYNIDEHFQATASWPTKIIY
                     LYISLLAARPKYYFAWTLADAINNAAGFGFRGYDENGAARWDLISNLRIQQIEMSTSF
                     KMFLDNWNIQTALWLKRVCYERTSFSPTIQTFILSAIWHGVYPGYYLTFLTGVLMTLA
                     ARAMRNNFRHYFIEPSQLKLFYDVITWIVTQVAISYTVVPFVLLSIKPSLTFYSSWYY
                     CLHILGILVLLLLPVKKTQRRKNTHENIQLSQSKKFDEGENSLGQNSFSTTNNVCNQN
                     QEIASRHSSLKQ"
     exon            146..291
                     /gene="MBOAT2"
                     /gene_synonym="LPAAT; LPCAT; LPCAT4; LPEAT; LPLAT 2;
                     LPLAT13; OACT2"
                     /inference="alignment:Splign:2.1.0"
     exon            292..369
                     /gene="MBOAT2"
                     /gene_synonym="LPAAT; LPCAT; LPCAT4; LPEAT; LPLAT 2;
                     LPLAT13; OACT2"
                     /inference="alignment:Splign:2.1.0"
     exon            370..465
                     /gene="MBOAT2"
                     /gene_synonym="LPAAT; LPCAT; LPCAT4; LPEAT; LPLAT 2;
                     LPLAT13; OACT2"
                     /inference="alignment:Splign:2.1.0"
     exon            466..521
                     /gene="MBOAT2"
                     /gene_synonym="LPAAT; LPCAT; LPCAT4; LPEAT; LPLAT 2;
                     LPLAT13; OACT2"
                     /inference="alignment:Splign:2.1.0"
     exon            522..576
                     /gene="MBOAT2"
                     /gene_synonym="LPAAT; LPCAT; LPCAT4; LPEAT; LPLAT 2;
                     LPLAT13; OACT2"
                     /inference="alignment:Splign:2.1.0"
     exon            577..760
                     /gene="MBOAT2"
                     /gene_synonym="LPAAT; LPCAT; LPCAT4; LPEAT; LPLAT 2;
                     LPLAT13; OACT2"
                     /inference="alignment:Splign:2.1.0"
     exon            761..953
                     /gene="MBOAT2"
                     /gene_synonym="LPAAT; LPCAT; LPCAT4; LPEAT; LPLAT 2;
                     LPLAT13; OACT2"
                     /inference="alignment:Splign:2.1.0"
     exon            954..1057
                     /gene="MBOAT2"
                     /gene_synonym="LPAAT; LPCAT; LPCAT4; LPEAT; LPLAT 2;
                     LPLAT13; OACT2"
                     /inference="alignment:Splign:2.1.0"
     exon            1058..1122
                     /gene="MBOAT2"
                     /gene_synonym="LPAAT; LPCAT; LPCAT4; LPEAT; LPLAT 2;
                     LPLAT13; OACT2"
                     /inference="alignment:Splign:2.1.0"
     exon            1123..1255
                     /gene="MBOAT2"
                     /gene_synonym="LPAAT; LPCAT; LPCAT4; LPEAT; LPLAT 2;
                     LPLAT13; OACT2"
                     /inference="alignment:Splign:2.1.0"
     exon            1256..1407
                     /gene="MBOAT2"
                     /gene_synonym="LPAAT; LPCAT; LPCAT4; LPEAT; LPLAT 2;
                     LPLAT13; OACT2"
                     /inference="alignment:Splign:2.1.0"
     exon            1408..7622
                     /gene="MBOAT2"
                     /gene_synonym="LPAAT; LPCAT; LPCAT4; LPEAT; LPLAT 2;
                     LPLAT13; OACT2"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2171..2176
                     /regulatory_class="polyA_signal_sequence"
                     /gene="MBOAT2"
                     /gene_synonym="LPAAT; LPCAT; LPCAT4; LPEAT; LPLAT 2;
                     LPLAT13; OACT2"
                     /note="hexamer: AATAAA"
     polyA_site      2192
                     /gene="MBOAT2"
                     /gene_synonym="LPAAT; LPCAT; LPCAT4; LPEAT; LPLAT 2;
                     LPLAT13; OACT2"
                     /note="major polyA site"
     regulatory      7601..7606
                     /regulatory_class="polyA_signal_sequence"
                     /gene="MBOAT2"
                     /gene_synonym="LPAAT; LPCAT; LPCAT4; LPEAT; LPLAT 2;
                     LPLAT13; OACT2"
                     /note="hexamer: ATTAAA"
     polyA_site      7622
                     /gene="MBOAT2"
                     /gene_synonym="LPAAT; LPCAT; LPCAT4; LPEAT; LPLAT 2;
                     LPLAT13; OACT2"
                     /note="major polyA site"
ORIGIN      
        1 atcctcgtcg tcgcccggca cagcgcgagc gggcgagcgg cgcgggcggc cggagcgccg
       61 aggcccggcc atggccacca ccagcaccac gggctccacc ctgctgcagc ccctcagcaa
      121 cgccgtgcag ctgcccatcg accaggtcaa ctttgtagtg tgccaactct ttgccttgct
      181 agcagccatt tggtttcgaa cttatctaca ttcaagcaaa actagctctt ttataagaca
      241 tgtagttgct acccttttgg gcctttatct tgcacttttt tgctttggat ggtatgcctt
      301 acactttctt gtacaaagtg gaatttccta ctgtatcatg atcatcatag gagtggagaa
      361 catgcacaat tactgctttg tgtttgctct gggatacctc acagtgtgcc aagttactcg
      421 agtctatatc tttgactatg gacaatattc tgctgatttt tcaggcccaa tgatgatcat
      481 tactcagaag atcactagtt tggcttgcga aattcatgat gggatgtttc ggaaggatga
      541 agaactgact tcctcacaga gggatttagc tgtaaggcgc atgccaagct tactggagta
      601 tttgagttac aactgtaact tcatggggat cctggcaggc ccactttgct cttacaaaga
      661 ctacattact ttcattgaag gcagatcata ccatatcaca caatctggtg aaaatggaaa
      721 agaagagaca cagtatgaaa gaacagagcc atctccaaat actgcggttg ttcagaagct
      781 cttagtttgt gggctgtcct tgttatttca cttgaccatc tgtacaacat tacctgtgga
      841 gtacaacatt gatgagcatt ttcaagctac agcttcgtgg ccaacaaaga ttatctatct
      901 gtatatctct cttttggctg ccagacccaa atactatttt gcatggacgc tagctgatgc
      961 cattaataat gctgcaggct ttggtttcag agggtatgac gaaaatggag cagctcgctg
     1021 ggacttaatt tccaatttga gaattcaaca aatagagatg tcaacaagtt tcaagatgtt
     1081 tcttgataat tggaatattc agacagctct ttggctcaaa agggtgtgtt atgaacgaac
     1141 ctccttcagt ccaactatcc agacgttcat tctctctgcc atttggcacg gggtataccc
     1201 aggatattat ctaacgtttc taacaggggt gttaatgaca ttagcagcaa gagctatgag
     1261 aaataacttt agacattatt tcattgaacc ttcccaactg aaattatttt atgatgttat
     1321 aacatggata gtaactcaag tagcaataag ttacacagtt gtgccatttg tgcttctttc
     1381 tataaaacca tcactcacgt tttacagctc ctggtattat tgcctgcaca ttcttggtat
     1441 cttagtatta ttgttgttgc cagtgaaaaa aactcaaaga agaaagaata cacatgaaaa
     1501 cattcagctc tcacaatcca aaaagtttga tgaaggagaa aattctttgg gacagaacag
     1561 tttttctaca acaaacaatg tttgcaatca gaatcaagaa atagcctcga gacattcatc
     1621 actaaagcag tgatcgggaa ggctctgagg gctgtttttt ttttttgatg ttaacagaaa
     1681 ccaatcttag caccttttca aggggtttga gtttgttgga aaagcagtta actgggggga
     1741 aatggacagt tatagataag gaatttcctg tacaccagat tggaaatgga gtgaaacaag
     1801 ccctcccatg ccatgtctcc gtgggccacg ccttatgtaa gaatatttcc atatttcagt
     1861 gggcactccc aacctcagca cttgtccgta gggtcacacg cgtgccctgt tgctgaatgt
     1921 atgttgcgta tcccaaggca ctgaagaggt ggaaaaataa tcgtgtcaat ctggatgata
     1981 gagagaaatt aacttttcca aatgaatgtc ttgccttaaa ccctctattt cctaaaatat
     2041 tgttcctaaa tggtattttc aagtgtaata ttgtgagaac gctactgcag tagttgatgt
     2101 tgtgtgctgt aaaggatttt aggaggaatt tgaaacagga tatttaagag tgtggatatt
     2161 tttaaaatgc aataaacatc tcagtatttg aagggttttc ttaaagtatg tcaaatgact
     2221 acaatccata gtgaaactgt aaacagtaat ggacgccaaa ttataggtag ctgattttgc
     2281 tggagagttt aattaccttg tgcagtcaaa gagcgcttcc agaaggaatc tcttaaaaca
     2341 taatgagagg tttggtaatg tgatatttta agcttattct ttttcttaaa agagagaggt
     2401 gacgaaggaa ggcaggaatg aagaagcact gcgtggcctc cggtggaatg cacggggcac
     2461 agccgcgact ctgcaggcag cttccccccc atgccagggc tctgcgccgt catgtgagac
     2521 ttaaaaaaaa agttgaatga cttcgtgata ctttggactt ctaaattaaa tttatcaggc
     2581 ataaattatg tagaattaga ggctttgaaa ataatactgg taggttgctc aaaggttttg
     2641 aaagagaaat cgctaggtag gttactatct ggctaatcca tttcttatcc ttgacaattt
     2701 aattcatatt tgggaaactt ttagggaaat gaaaaataaa agtcactgag tctgggtgac
     2761 attttttaag aataatataa attcagtttc aaactcttct cacattaaaa ttttgctgtg
     2821 aactcttact aaaatgagtt ttaggttctg taagtggaaa aatgtgcttt tattttatgg
     2881 gccattttta ccacaactaa tcttgccttg gattactaag catctcctgc gatcccacag
     2941 aggactgtgg tggccacagg agctgaaagc agaagagtgg gatttgatgc caggcagtgg
     3001 agtggcctca gccccagatt gtacctcctg ccctgtagga ggggaggggg caaagccttc
     3061 tgacttcacc tttgtttgac ctatgtatgg aacttacttt tactttttgc cttaaatttt
     3121 taatgaaatg caaattttct gtgatggggt tctctctctc tttttttcgg ggggtggagt
     3181 cactaataaa tttgcaaatg aagttaaaga caaggcaacc atctggctta tgctatataa
     3241 tacttcattt aaagaagaaa ggaaaagcaa atgcacttgc agcttttgag gtctcagcaa
     3301 aaatgggcat gtgtcttttt tgaagtttag aaatatccta atctattttt atttatctaa
     3361 aagtaagtgt tttccggctg ataaggctaa ccctacccag gaaaggattg ataactaaat
     3421 aaatttcctc tgttttccca tgcattgaaa ttatgttggc tgagcatggt ggctcacacc
     3481 tgtaatccta gcactttggg aggccgaggt gggcggatca cttgaggtca ggagttggag
     3541 accagcctgg ccaacgtggt gaatccccgt ctctactgaa aacacaaaaa ttagacgggc
     3601 atggtggcgc acacctgtaa tcccagctac ttgggaggct gaggcaggag aattgcttga
     3661 acctgggagg tggaggttgc agtgagctaa aattgtgcca ctgcactcca gcctgggtga
     3721 cagaggaaga ctccgtctca caaaaaaaaa aaaagaaaaa agaaattatg ccagctgttt
     3781 aatgtgagag aatagaaaga atgttcatgg aatgtacctg ccctgtaaaa tgtttgatca
     3841 ttttcattaa tgttgcagag aatccgactg ctattaagag aaagtgaaca aattaagaat
     3901 ttaaaagaca ggttcaggca tgtcataagt gaaaacaaga aggcttaata caaacttgtt
     3961 gggttttgtt cgtgtgtgtg tgtgtgtgtg tgtgtgtgtt tttttttggt tcagcctatc
     4021 tagccaccta caaataatca catttctgtt acctgaattt atttctcagc ctgtaaacct
     4081 tagtcactgt tacctgtttc ttgctcagtg aatatgatct tggcactgtc atctagaaag
     4141 caagatattt gattggtttt ctggttcctt cgaagataat aattccatat ccagtttgac
     4201 tgattttcat acccctgaat caactagtta ttttcatgaa atggtttttg gatatctctc
     4261 ctctagtttg gagaagtaat aatcacaaag attaatattt tgcttctagt acttacagta
     4321 gaagaatttt aaactggtac gtctactcct gttaaataga aaggggattc gttgtattat
     4381 gtgcttgctt ttttttaatc aatagaataa gattcaatgc atatttatgt tttatatttt
     4441 ccactattca ggtatcatga aatcactcta gagatgatca atcaacatca tatttatact
     4501 tttggttaat tatatactac tcagggaaaa aatgaacaaa aataactact catccttcaa
     4561 tttcattttc ttgaaacagt aagagtataa tttggtatgc ctcagctgtc accattttat
     4621 aagtggctca ttctgttctt aaagtaagta tttttattgg aactcagggt aattggggga
     4681 atttatttag cttctaaaat atccggcagg atagagaaga tttatttggc ttcaaaaatg
     4741 tctggtgacc acttctctta ttagccacta ctgcccattt gcttcaaaaa tatatttatt
     4801 ggtctccacc atgtgtgaca cacacaggat ttccaaacat accacttttg agaaaaatgt
     4861 gcagtaaaaa ggaggtttct agaaagtgac agtaactcac atttaagcac tagctgacct
     4921 aggaggagac ctggatcttc attctggttc tgcctttcat gagacttaag acttggagga
     4981 gccacctgtc ctgtagaccc caagttcctc agccataagc aaacgggtta atcctaagag
     5041 ttcaggacca gttgggtgtc gtgaacggag ccattagcaa ggtctgtagg attcaaggac
     5101 ttgggcacat tcacagtcca cactattgtc atggtcattg acttactact tgagctcaaa
     5161 gccctgacat ttcaaaaggt tgtcatgata acagtgaaac ctctgaatcc cttaaatcag
     5221 aaggcatggc aacatacttt ttctactggc aatagctctt acaatgagtg tttcataatg
     5281 aaatagtctc tgctgaagaa aacatgtttt ccttttgctc tctctgcttt gttggtttct
     5341 gtgctgtgtg gaattggaga agatatatgc tctgaaatat tttatacaga ttactgacta
     5401 ctggacaggg tttaccacta tataacatct caaagttatt caaggatatt taaagcatat
     5461 ttagtttagt tacaccttat tttaaaccgc agaaaacaat agctttaaaa tttttgccat
     5521 taaaataatt ataaatttat acttttactc aaggactaga tcacagtttt aggacaaaaa
     5581 tctctcctat ttaaagttca taccttgtaa gtatttagtt tgtatattca tgaacaaatc
     5641 tggacattta tacttttttt gtttccttat caactgttca caattattag ttaattggtc
     5701 ttaacagttc tacattataa ttgaaagaaa aattacttga gaaaataatt gtttcagaat
     5761 agtgcctact atatctgtgt cagctaaaaa tttgtccaga gttttagata taagctagta
     5821 ttttgtggag ttttatccag gcgttaatag ttcttcctgg ctgaaattta atataggtgc
     5881 agaatcctaa ataacactgt gagatgtaat cttaactgcc ctcaatacct tataaaactg
     5941 ctgcatttaa cccagtgtgc atttaatgag tggctggtcg ttgatacact catcttagat
     6001 gctgaaattt ctgttttctc cagcccttgt aaaagtgggt ttcttgatga acgcgtgctc
     6061 ccaatgctga agcaaaagat ttgcatttaa ggagagaaat acaccctgaa atttgagttt
     6121 gaaagattag aacatagagg gtctctacag tgtttttctg caacaccaag tagtcaaatc
     6181 tatttataga aactctgatt acaacagaaa ttttaaaatg aaattttcca catcggtatt
     6241 ttgtaggaaa gctcttataa tcaatgctta agctgctttt tgaggctttt cttgtacaga
     6301 ggttgcagcc aattacattt taattggtag gctgctgaat aatgtttttg tatgttttaa
     6361 aataatattt attttaatag gttttttaac attatgcaaa tcccaataaa gaactgacac
     6421 gttccatagg ccattgactg ggaaattttg tgaaacacag cctaaataca cagtttttac
     6481 accaactaat ttgtcttgcc tttaaaactg attataactc ttctttaagt acaactttta
     6541 taaagaaaaa atacaacact aagactgtat gttctgtaaa ttatagtgtg atgacccatg
     6601 cagaaccgct gtctgaagct tactcagcga ttcatagcca tctccagcca tgttttatca
     6661 aatcacacac taaaaataaa tggaaatgct acagtgaaaa accaaaagtt acagagcaac
     6721 ataagtaaaa tgactaggca gtttcttagt aacatgtttg aaatgggaaa ggtgactgac
     6781 tgcctttcac cagagtctta gctgtttcac gttcactatt ttaggttaat tttcttggga
     6841 aatcaatttg aatattcccc cctgtccttt tgcattaaag gacgaaaata tatgttgaga
     6901 gtttgacaga ctttttaaat atgcctcttt cccaatttta tgtatttttg gttctgcgca
     6961 cacagattta tcaatgaagt acatttgcct ctggctttat cacaaggaaa aaggaatcaa
     7021 acattgaaca caaatgtgtt ccaaaccagt cttgtccatc ttgtcacttt tatgtgactg
     7081 ctcctctgaa ccagaagggg cacgatagaa ggccatagga atgaaagtaa atcattcagg
     7141 tgaagtgaga aattcttcca tatacagagt gaaaatgtgt gatttcattc ctgccttcct
     7201 ttaaacgttg tcttgatctc tgcctagtag tagttgagcc ctcagtcgcc caaacatgag
     7261 gagagaccca actccagcag ccagaattta gtatttacat ttgccttccc aagttgagaa
     7321 tagaatgtgg tgttctgtgc tttctgtttt tattattcca aaatattttt ttaaagaagt
     7381 gttatttttc aacagattca taaattagtt cctgatgtac ggtaaattaa aactcccact
     7441 gtgtcagtca aactgagatg tgctcatttc ataaccactc atttctagtc tgtcagagct
     7501 gcactggtgg cttattgctg gtttttaaag gtgtttttaa cttacatgta acatgtttag
     7561 gacatgtttt ttttttctaa tttgtgtgtc tttacaactg attaaacagt agtttaaaaa
     7621 ta
//
