LOCUS       NM_001364674             841 bp    mRNA    linear   PRI 12-OCT-2024
DEFINITION  Homo sapiens methyl-CpG binding domain protein 3 like 2B (MBD3L2B),
            mRNA.
ACCESSION   NM_001364674
VERSION     NM_001364674.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 841)
  AUTHORS   Gaudet,P., Livstone,M.S., Lewis,S.E. and Thomas,P.D.
  TITLE     Phylogenetic-based propagation of functional annotations within the
            Gene Ontology consortium
  JOURNAL   Brief Bioinform 12 (5), 449-462 (2011)
   PUBMED   21873635
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC010606.7 and AC025278.5.
            
            On May 20, 2020 this sequence version replaced NM_001364674.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMEA1968968,
                              SAMN03465418 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000636986.2/ ENSP00000489619.1
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-79                AC010606.7         103729-103807
            80-590              AC010606.7         105430-105940
            591-841             AC025278.5         110396-110646       c
FEATURES             Location/Qualifiers
     source          1..841
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="19"
                     /map="19p13.2"
     gene            1..841
                     /gene="MBD3L2B"
                     /note="methyl-CpG binding domain protein 3 like 2B"
                     /db_xref="GeneID:729458"
                     /db_xref="HGNC:HGNC:53435"
     exon            1..79
                     /gene="MBD3L2B"
                     /inference="alignment:Splign:2.1.0"
     CDS             35..649
                     /gene="MBD3L2B"
                     /codon_start=1
                     /product="methyl-CpG-binding domain protein 3-like 2B"
                     /protein_id="NP_001351603.1"
                     /db_xref="CCDS:CCDS92501.1"
                     /db_xref="GeneID:729458"
                     /db_xref="HGNC:HGNC:53435"
                     /translation="MGEPAFTSFPSLPVLGKLKRNMMPWALQKKREIHMAKAHRRRAA
                     RSALPMRLTSCIFRRPVTRIRSHPDNQVRRRKGDEHLEKPQQLCAYRRLQALQPCSSQ
                     GEGSSPLHLESVLSILAPGTAGESLDRAGAERVRSPLEPTPGRFPAVAGGPTPGMGCQ
                     LPPPLSGQLVTPADIRRQARRVKKARERLAKALQADRLARRAEM"
     exon            80..841
                     /gene="MBD3L2B"
                     /inference="alignment:Splign:2.1.0"
     regulatory      820..825
                     /regulatory_class="polyA_signal_sequence"
                     /gene="MBD3L2B"
                     /note="hexamer: ATTAAA"
     polyA_site      841
                     /gene="MBD3L2B"
                     /note="major polyA site"
ORIGIN      
        1 caggagtggg gtcagcagga ggaactctac agctatggga gaacctgcgt tcacctcttt
       61 tccaagcctg cctgttctgg ggaagctcaa aaggaacatg atgccctggg ctttacagaa
      121 gaaacgagaa atccacatgg ccaaggccca tcggagacga gctgcgaggt ctgctctccc
      181 catgagactc accagctgca tcttccggag gccggtgaca aggatcaggt ctcatcctga
      241 caaccaggtc agacgcagaa aaggggacga gcacctggag aagccgcagc aactctgcgc
      301 ctaccggaga ctgcaggccc tgcagccctg cagcagccaa ggagaaggtt caagtccact
      361 gcatttggag agcgtcttaa gtatccttgc accggggacg gccggtgaat ctctggacag
      421 agctggtgct gagcgtgtgc gcagcccgct tgagcccacc cctgggcggt ttccagctgt
      481 ggcagggggg ccaaccccag gaatgggttg tcagctccca ccgcccctct ctggccaatt
      541 ggtgactcct gcagatatcc ggagacaggc caggagggtg aagaaagcca gggagagact
      601 ggccaaggcc ttgcaggcag acaggctggc caggcgggca gaaatgtgac aggtggatga
      661 agtgcaggag gagggggtgc tgagaagctg tggggtgtgg ccccgcagtt ggggggtgag
      721 tcagtgggga cagtcctggg ttttgaatcc ctatctttta atgcccgtcc tctttcctgc
      781 tatgaattgt cacactttgt acttccccac cagttcttta ttaaaagcat ttgaaaggca
      841 a
//
