LOCUS       NM_052967               1260 bp    mRNA    linear   PRI 07-FEB-2024
DEFINITION  Homo sapiens MAS1 proto-oncogene like, G protein-coupled receptor
            (MAS1L), mRNA.
ACCESSION   NM_052967
VERSION     NM_052967.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1260)
  AUTHORS   Gembardt,F., Grajewski,S., Vahl,M., Schultheiss,H.P. and Walther,T.
  TITLE     Angiotensin metabolites can stimulate receptors of the Mas-related
            genes family
  JOURNAL   Mol Cell Biochem 319 (1-2), 115-123 (2008)
   PUBMED   18636314
  REMARK    GeneRIF: Mas, MrgD, and MRG mediated Ang IV-stimulated AA release
            that was highest for Mas. While Ang III activated Mas and MrgX2,
            Ang II stimulated AA release via Mas and MRG.
REFERENCE   2  (bases 1 to 1260)
  AUTHORS   Dong,X., Han,S., Zylka,M.J., Simon,M.I. and Anderson,D.J.
  TITLE     A diverse family of GPCRs expressed in specific subsets of
            nociceptive sensory neurons
  JOURNAL   Cell 106 (5), 619-632 (2001)
   PUBMED   11551509
REFERENCE   3  (bases 1 to 1260)
  AUTHORS   Monnot,C., Weber,V., Stinnakre,J., Bihoreau,C., Teutsch,B.,
            Corvol,P. and Clauser,E.
  TITLE     Cloning and functional characterization of a novel mas-related
            gene, modulating intracellular angiotensin II actions
  JOURNAL   Mol Endocrinol 5 (10), 1477-1487 (1991)
   PUBMED   1723144
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BC095511.1 and BC101176.2.
            
            On Aug 2, 2016 this sequence version replaced NM_052967.1.
            
            ##Evidence-Data-START##
            Transcript is intronless :: BC095511.1 [ECO:0000345]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000377127.4/ ENSP00000366331.3
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-54                BC095511.1         12-65
            55-1191             BC101176.2         1-1137
            1192-1260           BC095511.1         1203-1271
FEATURES             Location/Qualifiers
     source          1..1260
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="6"
                     /map="6p22.1"
     gene            1..1260
                     /gene="MAS1L"
                     /gene_synonym="dJ994E9.2; MAS-L; MRG"
                     /note="MAS1 proto-oncogene like, G protein-coupled
                     receptor"
                     /db_xref="GeneID:116511"
                     /db_xref="HGNC:HGNC:13961"
                     /db_xref="MIM:607235"
     exon            1..1260
                     /gene="MAS1L"
                     /gene_synonym="dJ994E9.2; MAS-L; MRG"
                     /inference="alignment:Splign:2.1.0"
     CDS             55..1191
                     /gene="MAS1L"
                     /gene_synonym="dJ994E9.2; MAS-L; MRG"
                     /note="mas-related G protein-coupled MRG; MAS-R;
                     MAS1-like; MAS1 oncogene-like"
                     /codon_start=1
                     /product="mas-related G-protein coupled receptor MRG"
                     /protein_id="NP_443199.1"
                     /db_xref="CCDS:CCDS4661.1"
                     /db_xref="GeneID:116511"
                     /db_xref="HGNC:HGNC:13961"
                     /db_xref="MIM:607235"
                     /translation="MVWGKICWFSQRAGWTVFAESQISLSCSLCLHSGDQEAQNPNLV
                     SQLCGVFLQNETNETIHMQMSMAVGQQALPLNIIAPKAVLVSLCGVLLNGTVFWLLCC
                     GATNPYMVYILHLVAADVIYLCCSAVGFLQVTLLTYHGVVFFIPDFLAILSPFSFEVC
                     LCLLVAISTERCVCVLFPIWYRCHRPKYTSNVVCTLIWGLPFCINIVKSLFLTYWKHV
                     KACVIFLKLSGLFHAILSLVMCVSSLTLLIRFLCCSQQQKATRVYAVVQISAPMFLLW
                     ALPLSVAPLITDFKMFVTTSYLISLFLIINSSANPIIYFFVGSLRKKRLKESLRVILQ
                     RALADKPEVGRNKKAAGIDPMEQPHSTQHVENLLPREHRVDVET"
ORIGIN      
        1 atggaccact gctcctgact gtgatgttgt ggcccactca ggtcccagca ccccatggtc
       61 tgggggaaaa tttgctggtt cagccagagg gctggatgga cagtgtttgc tgagtcacag
      121 atatctctct catgtagcct ttgtctccac agtggtgacc aggaggcaca gaacccaaac
      181 ctggtatctc agctctgtgg cgtctttctt caaaatgaga cgaatgaaac catacatatg
      241 cagatgagca tggcagtggg acagcaggcc ctgcccttga atatcattgc ccccaaggct
      301 gtgctggtct ccctctgtgg ggtcttattg aatggcactg tcttctggct gctttgctgt
      361 ggggccacga atccctacat ggtatacatc ctccacctgg tcgctgctga cgtgatctat
      421 ctttgctgct cggcagtggg gttcttacag gtgactctgc taacttatca tggagtcgtg
      481 ttttttatcc ctgatttcct ggccatattg tctcccttct cctttgaggt gtgtctctgt
      541 ctcctggtgg ccatcagcac agagcggtgt gtgtgtgtcc tcttccccat ctggtacaga
      601 tgccaccgcc caaaatacac atctaatgtt gtctgcaccc tcatctgggg cctgcctttt
      661 tgcatcaaca tagtaaaatc acttttccta acttactgga aacatgtaaa ggcatgtgtc
      721 atatttctaa agctttctgg gctcttccat gctatccttt cacttgtgat gtgtgtgtcg
      781 agtctgactc tactcattag attcctgtgc tgctcccagc agcaaaaggc caccagggtc
      841 tatgcggtgg tgcagatctc ggcccccatg ttcctactct gggccctacc cctgagcgtg
      901 gcacccctca taacagattt caaaatgttt gtcaccacct cctatttaat ttccttgttc
      961 ctcattataa acagcagcgc caaccctatc atttatttct ttgtggggag cctcagaaag
     1021 aaaaggctga aggaatctct cagagtgatt ctccaacggg cgttagcaga taagccagag
     1081 gtggggagga acaaaaaggc agctggcatc gacccaatgg agcaaccaca ctctactcag
     1141 catgtggaga accttcttcc cagggagcac agggtcgatg tggaaacata atttcccaca
     1201 tctgagctgg ggaattgtac acatagtaac ccagcctgtt ctgcatcata aggctgctgc
//
