LOCUS       XM_047445528            5789 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens membrane associated ring-CH-type finger 7
            (MARCHF7), transcript variant X17, mRNA.
ACCESSION   XM_047445528
VERSION     XM_047445528.1
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000002.12) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5789
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="2"
     gene            1..5789
                     /gene="MARCHF7"
                     /gene_synonym="AXO; AXOT; MARCH-VII; MARCH7; RNF177"
                     /note="membrane associated ring-CH-type finger 7; Derived
                     by automated computational analysis using gene prediction
                     method: Gnomon. Supporting evidence includes similarity
                     to: 5 mRNAs, 25 ESTs, 1420 long SRA reads, 3 Proteins, and
                     98% coverage of the annotated genomic feature by RNAseq
                     alignments, including 59 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:64844"
                     /db_xref="HGNC:HGNC:17393"
                     /db_xref="MIM:613334"
     CDS             158..2104
                     /gene="MARCHF7"
                     /gene_synonym="AXO; AXOT; MARCH-VII; MARCH7; RNF177"
                     /codon_start=1
                     /product="E3 ubiquitin-protein ligase MARCHF7 isoform X3"
                     /protein_id="XP_047301484.1"
                     /db_xref="GeneID:64844"
                     /db_xref="HGNC:HGNC:17393"
                     /db_xref="MIM:613334"
                     /translation="MESKPSRIPRRISVQPSSSLSARMMSGSRGSSLNDTYHSRDSSF
                     RLDSEYQSTSASASASPFQSAWYSESEITQGARSRSQNQQRDHDSKRPKLSCTNCTTS
                     AGRNVGNGLNTLSDVQDRVPSYSQGARPKENSMSTLQLNTSSTNHQLPSEHQTILSSR
                     DSRNSLRSNFSSRESESSRSNTQPGFSYSSSRDEAPIISNSERVVSSQRPFQESSDNE
                     GRRTTRRLLSRIASSMSSTFFSRRSSQDSLNTRSLNSENSYVSPRILTASQSRSNVPS
                     ASEVPDNRASEASQGFRFLRRRWGLSSLSHNHSSESDSENFNQESEGRNTGPWLSSSL
                     RNRCTPLFSRRRREGRDESSRIPTSDTSSRSHIFRRESNEVVHLEAQNDPLGAAANRP
                     QASAASSSATTGGSTSDSAQGGRNTGISGILPGSLFRFAVPPALGSNLTDNVMITVDI
                     IPSGWNSADGKSDKTKSAPSRDPERLQKIKESLLLEDSEEEEGDLCRICQMAAASSSN
                     LLIEPCKCTGSLQYVHQDCMKKWLQAKINSGSSLEAVTTCELCKEKLELNLEDFDIHE
                     LHRAHANEQAEYEFISSGLYLVVLLHLCEQSFSDMMGNTNEPSTRVRFINLARTLQAH
                     MEDLETSEDDSEEDGDHNRTFDIA"
ORIGIN      
        1 ggttctgcgc cggatccggg agaggggcgg gcgccattgt gcttcgctgc cgactgcatt
       61 tcctcagtca cgggcctaga actccaagga gaaaggcggc ggaattcatg atttgttcct
      121 gtagctgaaa catacattga atgaaaaatc tttaagaatg gagtctaaac cttcaaggat
      181 tccaagaaga atttctgttc aaccttccag ctccttaagt gctaggatga tgtctggaag
      241 cagaggaagt agtttaaatg atacctatca ctcaagagac tcttcattta gattggattc
      301 tgaatatcag tctacatcag catcagcatc tgcgtcacca tttcaatctg catggtatag
      361 tgaatctgag ataactcagg gagcacgctc aagatcgcag aaccagcaac gggatcatga
      421 ttcaaaaaga cctaaacttt cctgtacaaa ctgtactacc tcagctggga gaaatgttgg
      481 aaatggttta aacacattat cagatgttca agacagagtt ccttcatatt cacaaggagc
      541 aagaccaaaa gaaaactcaa tgagcacttt acagttgaat acatcatcca caaaccacca
      601 attgccttct gaacatcaga ccatactaag ttctagggac tccagaaatt ctttaagatc
      661 aaatttttct tcaagagaat cagaatcttc ccgaagcaat acgcagcctg gattttctta
      721 cagttcaagt agagatgaag ccccaatcat aagcaattca gaaagggttg tttcatctca
      781 aagaccattt caagaatctt ctgacaatga aggtaggcgg acaacgagga gattgctgtc
      841 acgcatagct tctagcatgt catctacttt tttttcacga agatctagtc aggattcctt
      901 gaatacaaga tcattgaatt ctgaaaattc ttacgtttct ccaagaatct tgacagcttc
      961 acagtcccgt agtaatgtac catcagcttc tgaagttccc gataataggg catctgaagc
     1021 ttctcaggga tttcgatttc ttaggcgaag atggggtttg tcatctctta gccacaatca
     1081 tagctctgag tcagattcag aaaattttaa ccaagaatct gaaggtagaa atacaggacc
     1141 atggttatct tcctcactta gaaatagatg cacacctttg ttctctagaa ggaggcgaga
     1201 gggaagagat gaatcttcaa ggatacctac ctctgataca tcatctagat ctcatatttt
     1261 tagaagagaa tcaaatgaag tggttcacct tgaagcacag aatgatcctc ttggagctgc
     1321 tgccaacaga ccacaagcat ctgcagcatc aagcagtgcc acaacaggtg gctctacatc
     1381 agattcggct caaggtggaa gaaatacagg aatatcaggg attcttcctg gttccttatt
     1441 ccggtttgca gtccctccag cacttgggag taatttgacc gacaatgtca tgatcacagt
     1501 agatattatt ccttcaggtt ggaattcagc tgatggtaaa agtgataaaa ctaaaagtgc
     1561 gccttcaaga gatccagaaa gattgcagaa aataaaagag agcctccttt tagaggactc
     1621 agaagaagaa gaaggtgact tatgtagaat ttgtcaaatg gcagctgcat catcatctaa
     1681 tttgctgata gagccatgca agtgcacagg aagtttgcag tatgtccacc aagactgtat
     1741 gaaaaagtgg ttacaggcca aaattaactc tggttcttca ttagaagctg taaccacctg
     1801 tgaactatgt aaagagaagt tggagcttaa cctggaggat tttgatattc atgaactaca
     1861 tagagctcat gcaaatgaac aagctgagta tgagtttatc agctctggtc tctacctagt
     1921 ggtgttattg cacttgtgcg aacaaagctt ttctgatatg atgggaaata caaatgaacc
     1981 aagcacacgt gtccgattta ttaaccttgc aagaactctt caggcacata tggaagatct
     2041 cgaaacttca gaggatgatt ccgaagaaga cggagaccat aacaggacat ttgatattgc
     2101 ctaacttcat ataagacaga tggatgatct gtgaacataa gtgtttatta aaaatggcaa
     2161 ttaaatataa attacttttg tgggggaatg cctaataaat acattgacta tatataaaat
     2221 gaatatatac atacacatgt atgcctgtat atatatattc attctccagt gttgctgaat
     2281 taaaattctg ctggactttt taacatagca aatccgatgt ttataaactg gtaatcaaaa
     2341 aggttttttc ttttaggtga gtgggaaagt attacccttg ttttaaatat ctaagcaatg
     2401 cctatcaacc cttttttgtg ttatgattac tgtagtcata tttatgaaaa aaggtttgtg
     2461 ttttactctt gctagtgaga aaagtgggac aaaatatact tttgaaataa aatgctatat
     2521 ggcacctaat tattttttct tttaaaatgc cttaagttgc agtctcattt tgataatcat
     2581 ttgcttccag tgtttaaaaa ttaaaaaaag aatggggaga aggttatgag aagagcatta
     2641 ttaagtttcc aaatttaatt tgaattccaa attcacctag caataaaatc taatttttaa
     2701 aaagtatata aatataaaat gtataaatga tggatagatt tttgtattga tttgcaaaat
     2761 gcagattata tttgataggc tatagtatgt agatattcct tttaggaata ttacagctgt
     2821 aaattatatg agacttgcca gtcaaatgct atttggttta aaaaaattat tgcaatctca
     2881 agttaatgga atatttttaa atcccacatt cagagtttaa aacactggtt ttcaatgtgt
     2941 tttttagtgt tgtcacttgt ttatagataa atatataaat aacctgtttg gatcctggtc
     3001 ctttttaact gttccttggt aattctgagc atttatttga tgacttaata tttttcacta
     3061 cctttggaga acagatgaac attattcacc atgaatggat ctatactgtg tggtcatgag
     3121 ttgtgtatac ttccataaca ctgtattttt cttctgtcag tacccttagg atacacttta
     3181 aaacacctta aggtctgatg ttatggcaac aaactacttt ttcaaaccta aataggaacc
     3241 atgtaatttc tcaaaagtga ttgaacagtt tgcccacact tagtttgttg gtcttatgta
     3301 aaacattggc tcaaaataaa gtacacactg atttatttta ctgtttgaaa tgtttccttt
     3361 taaactggtg ctcaaagaag acatcagact tcataaccaa gaattttatt acaatttcaa
     3421 atctcatttt aagcaataat ataaatgttc taaaacattt gctcacctct tgccagttac
     3481 ctttgcattg tctgtcttaa agcaaaaata taaaatttaa gggtggtagt tttaatatat
     3541 tctgtgggtc ctaagggatg ctttgaattt gaagtatata tacttttaat aaaattcagt
     3601 atgacagttg tcttctgctt aacccataaa actttattta aaaaatttaa ctagatggta
     3661 caaaacattc attggtatgc acataattct gtatagtttt gttattaaat gctaaatgac
     3721 agtgataaca atggcttaag ctttacagta ttcttgtagt tccctagtac cacttagtat
     3781 ttaaatattg tcatattagc ttcagattat catgtaaatg acggtagagg aataagagaa
     3841 aaggctttca ttggttatca gttttaaatt ctgaacaaaa gagaccatac actgctcact
     3901 acaagaatgc aattttctaa gaaaatgtag tttaaaatgt tattctgaat atctgccaaa
     3961 gaattatatt gttattacta gctagaacca agatgttgaa gaaagcagtt tctacattct
     4021 ggatgtagta aacaagcctg cctgtgtaat ccaattatct cttcactaat gagtagataa
     4081 ggtgcctgtt atagatgttc tggtatataa agaaaaaatg taggccaagt gtggtggctc
     4141 acgcatgtaa tcccagcact ttgggagacc aaggtgggtg gatcacttga ggtcaggagt
     4201 ttgagaccag cccagtcaat atggcgaaac cccgtctcta ccaaaaatac aaaaagttag
     4261 ctgggtgtgg tgacagatgt ctgtggtccc agctactaag gaggctgagg caggagaatt
     4321 gcttgaaaac ctgcaaggcg gagattggag agagccaaga tcgagccact gcactgtagc
     4381 ctgggcagca cagtgagact ccatcatata tatatatata gcacttcatt accagaggcc
     4441 tcttggcctg ttgaaaaatg aaaccaaata ttgaaaatta aatcagagtt taaagcagct
     4501 attttggaag agctgccatt aggtagaaag tatcaaaatg tacaaaagaa agttgtatgg
     4561 gagttgagtg gaaggtagga tttaagagca gcactgccca ataaaacttc ctataatgaa
     4621 aatgttctat aatgtatgtt gcccagtaca gtagccacta accacctgtg atttgaacac
     4681 ttgacaatgt ggctaatgta attcgaaaac tggattttaa actaaattta cttaaatagc
     4741 ctcatgtggc tagtggctca ttggacattg tagttgtaga cgtttgagac tgttggtttt
     4801 aagttggact taatcacttt cctacccaaa ttctaccact cctttaagaa ctcctttaga
     4861 actcttttag ttcacataat acgccatatt ttttttactg tgcctgtagt tcttcaagga
     4921 gtggtacaat ttgggtagga aaaccaggca ggaattccag ggtagtgttc aatattgaca
     4981 ttagtaatag tctatcaata ataaaataga catctcaatc actatacaaa atctcagaaa
     5041 tgtaaagctc ttacagagca tgcttgtgct tgtgtaacag ctggtgtaat gcctgcattt
     5101 tcagtaccat gtagccgcac tgttaatagt tttctatcac tttttagtta ctcatgtctc
     5161 attaatgata gtgccattaa ttgtgatgag tgttttcgat tcatgtggtc aataaaaaga
     5221 gactacacaa gctggaactt tgttgccatt agtcaagcta gtgagatagt atatctatct
     5281 atctccccag aagaaagtaa gataattgat ggggtgtgga ttcagaagag ggattacttt
     5341 tctttgagcc tcagacttct agacagtata cttcagtcag taatggacca catatagaac
     5401 agtgtttcct tagtagacca tatttttact gtaccttttc tatatttaga tacacaaata
     5461 ttgtgttaca attgtctgca gtattcagca cagtaacatg ctgtgtaggt ttgggacaaa
     5521 ataggctcta ccatctgggt ttgtgtaaat acaagctgat tttcacacaa gattccctaa
     5581 ctatgcattt cttagaacgt atccccattg ataagtgata cgtgactaat ttacgtgaaa
     5641 tttatacatt ctttatcttt cctgtttttg gtttattgat ggtgaggaaa attactcgtt
     5701 tcagcttttt cattttttta ctccccaaat gattttcacc tttttcttaa aatgtacaat
     5761 aaatgcactg aaaactttga tcactgtca
//
