LOCUS       NM_024871               2064 bp    mRNA    linear   PRI 12-FEB-2025
DEFINITION  Homo sapiens MAP6 domain containing 1 (MAP6D1), mRNA.
ACCESSION   NM_024871
VERSION     NM_024871.4
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 2064)
  AUTHORS   Gory-Faure,S., Windscheid,V., Brocard,J., Montessuit,S.,
            Tsutsumi,R., Denarier,E., Fukata,Y., Bosc,C., Delaroche,J.,
            Collomb,N., Fukata,M., Martinou,J.C., Pernet-Gallay,K. and
            Andrieux,A.
  TITLE     Non-microtubular localizations of microtubule-associated protein 6
            (MAP6)
  JOURNAL   PLoS One 9 (12), e114905 (2014)
   PUBMED   25526643
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2064)
  AUTHORS   Gory-Faure,S., Windscheid,V., Bosc,C., Peris,L., Proietto,D.,
            Franck,R., Denarier,E., Job,D. and Andrieux,A.
  TITLE     STOP-like protein 21 is a novel member of the STOP family,
            revealing a Golgi localization of STOP proteins
  JOURNAL   J Biol Chem 281 (38), 28387-28396 (2006)
   PUBMED   16837464
  REMARK    GeneRIF: This paper describes the conserved domains, localization
            and function of the mouse MAP6D1 protein. It also compared the
            sequences of the related proteins in mouse, human and other
            species.
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from AK022810.1 and BC006434.1.
            
            On Nov 30, 2019 this sequence version replaced NM_024871.3.
            
            Summary: This gene encodes a protein highly similar to the mouse
            MAP6 domain containing 1 protein, which is related to the STOP
            proteins. Based on the study of the mouse protein, the encoded
            protein may function as a calmodulin-regulated neuronal protein
            that binds and stabilizes microtubules but also associates with the
            Golgi membranes through N-terminal palmitoylation. [provided by
            RefSeq, Oct 2008].
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC006434.1, AK022810.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1968540, SAMEA1968832
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000318631.8/ ENSP00000314560.4
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1317              AK022810.1         1-1317
            1318-2064           BC006434.1         1311-2057
FEATURES             Location/Qualifiers
     source          1..2064
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="3"
                     /map="3q27.1"
     gene            1..2064
                     /gene="MAP6D1"
                     /gene_synonym="MAPO6D1; SL21"
                     /note="MAP6 domain containing 1"
                     /db_xref="GeneID:79929"
                     /db_xref="HGNC:HGNC:25753"
                     /db_xref="MIM:610593"
     exon            1..431
                     /gene="MAP6D1"
                     /gene_synonym="MAPO6D1; SL21"
                     /inference="alignment:Splign:2.1.0"
     CDS             31..630
                     /gene="MAP6D1"
                     /gene_synonym="MAPO6D1; SL21"
                     /note="21 kDa STOP-like protein; STOP-Like protein 21 kD"
                     /codon_start=1
                     /product="MAP6 domain-containing protein 1"
                     /protein_id="NP_079147.1"
                     /db_xref="CCDS:CCDS3247.1"
                     /db_xref="GeneID:79929"
                     /db_xref="HGNC:HGNC:25753"
                     /db_xref="MIM:610593"
                     /translation="MAWPCISRLCCLARRWNQLDRSDVAVPLTLHGYSDLDSEEPGTG
                     GAASRRGQPPAGARDSGRDVPLTQYQRDFGLWTTPAGPKDPPPGRGPGAGGRRGKSSA
                     QSSAPPAPGARGVYVLPIGDADAAAAVTTSYRQEFQAWTGVKPSRSTKTKPARVITTH
                     TSGWDSSPGAGFQVPEVRKKFTPNPSAIFQASAPRILNV"
     exon            432..549
                     /gene="MAP6D1"
                     /gene_synonym="MAPO6D1; SL21"
                     /inference="alignment:Splign:2.1.0"
     exon            550..2064
                     /gene="MAP6D1"
                     /gene_synonym="MAPO6D1; SL21"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2023..2028
                     /regulatory_class="polyA_signal_sequence"
                     /gene="MAP6D1"
                     /gene_synonym="MAPO6D1; SL21"
                     /note="hexamer: ATTAAA"
     polyA_site      2064
                     /gene="MAP6D1"
                     /gene_synonym="MAPO6D1; SL21"
                     /note="major polyA site"
ORIGIN      
        1 gggagcgggg cggcgggcgc cggggctggc atggcgtggc cctgtatcag ccgcctgtgc
       61 tgcctggcgc ggcgctggaa ccagctggac cgctccgacg tggcggtgcc gctcactctg
      121 cacggctact cggacctcga cagcgaggag ccgggcacgg gcggcgccgc ctcgcgcagg
      181 ggccagcctc ccgcgggcgc ccgggattcc ggccgggacg tgccgctcac tcagtaccag
      241 cgggacttcg gcttgtggac cacgcccgcc gggcccaagg atccgccgcc ggggcgcgga
      301 ccgggggcgg gcggccgcag gggcaaatcc tccgcgcagt cctccgcgcc acctgcgccc
      361 ggcgcccgcg gggtctacgt gctgcccatc ggcgacgcgg acgcggctgc agcagtgacc
      421 acgtcgtaca gacaggaatt ccaggcttgg actggagtga agccctcaag atccacaaag
      481 acaaaaccag cccgagtcat cacaacccac acttcgggat gggacagcag ccctggggcc
      541 ggcttccagg tcccagaggt gaggaagaag ttcactccta acccctccgc catctttcag
      601 gcctcagctc cccggattct caacgtgtga ctgcctgcac cgtgacacca tggctgccga
      661 caggacaggg ctggggagcg gcctcaggac ccactgccgc ggggctgggc gagagcatgg
      721 catgggcccc tgcgggaggg cacagcccct ctcaaagctg tcaccagggc caaagtgctg
      781 gtgtggagca gatgcaccga tggacttggc acacccagct cagcctcaag catcctcttg
      841 agaagcctgt ggaaggctcc tgcgttcgtt aactgccatc tggccgtctc tcagttttga
      901 aatctctgag gagcctgagg atcaagtcag ttgggaaccg aattggtcca tggaagctga
      961 ggaatgtgga cacatccggc ccttgaaaga accagttatg tccacttttg gtggatttcc
     1021 caggatgcgt gagcacttga ttaatttcat aacctacagt gagacccttg gctcttccta
     1081 caaatggccc ctgcagttga agctgttgga atcttgggcc gtcacctgca tgactcatgg
     1141 tgatgctgag tatccaggag gaaatttcca gaagaaacag accgtcagtc acgggcttcc
     1201 acttcacaga cctccttatg gccaagatga gcctcatgtt ttaacaaaac agttcttggg
     1261 attgaatgac tcacatttac cttgtgctag gttctaaaga ttgaatccac attttgttac
     1321 taatgatttt cccgctaaca taaggatgat gagcagggca ctatcataca cactggctga
     1381 gaactggaac tgtttttggg aaggtggcat ttgtctcatt ccctgaaata ccttaaaatg
     1441 tcctctacac caacccttcc gtctaccctg ctcacatgta cagtgacggg gaactcacca
     1501 ccttttgaag aggcagttca ttttctttgc aaagctctct cctaacttcc tccgtaaatt
     1561 ccagccagca tggccacatg ggtcacgcct ggtgccttca cacgtttgag gggtcttcgt
     1621 ctctttttaa agcttagagg tacaagctca ggacagtctt cagtaaggaa atttgtggat
     1681 ttccctttgg atctttcttc ctctccagcc cacaagtggc tctagtgaga cgagcattta
     1741 agctgcaggt ggtggcactc gggtctcaga gccaccagac gtgcaggtgg gacagtggtt
     1801 ccagctccga ctgcctgtca gcgtccctcc caggtgctag ccctggcagg cacagccctc
     1861 ccctcatgcc agcaaaggaa atgctcttga tgagaggctc gctttaaaga agcccaaagc
     1921 gtgtgcttat ccaaggggtt cagctattcc tgacttcacg gcttgcatgt ttgatttttc
     1981 taagagaaaa gaggctgcct gctgggtgtc tgtggaaatg agattaaaaa ctgtacaatc
     2041 tcagatttta ctaaaatgca aaaa
//
